CN106659674A - 用于调节皮脂分泌的微藻和植物提取物 - Google Patents
用于调节皮脂分泌的微藻和植物提取物 Download PDFInfo
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- CN106659674A CN106659674A CN201580042070.6A CN201580042070A CN106659674A CN 106659674 A CN106659674 A CN 106659674A CN 201580042070 A CN201580042070 A CN 201580042070A CN 106659674 A CN106659674 A CN 106659674A
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Abstract
Description
提取物编码 | 钙质角毛藻矮变型 | 假微型海链藻 | Monodus subterraneus | 微小绿球藻 |
甲醇 | 54% | 39% | 20% | 24% |
乙醇 | 22% | 27% | 7-10% | 16% |
异丙醇 | 10% | 15% | 6-9% | 10% |
乙酸乙酯 | 9-12% | 18% | 4% | 5-8% |
水 | 64% | 22% | 26% | 22% |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比 | 0 | 100.0 | 1.4 | |
0 | 辣椒素 | 5μM | 90.3 | 1.8 | p<0.01 |
1 | EtOH | 0.1μg/ml | 50.2 | 1.3 | p<0.01 |
2 | EtOH | 1.0μg/ml | 78.6 | 2.0 | p<0.01 |
3 | EtOH | 10.0μg/ml | 49.2 | 1.6 | p<0.01 |
4 | 水 | 0.1μg/ml | 51.8 | 1.1 | p<0.01 |
5 | 水 | 1.0μg/ml | 50.4 | 1.1 | p<0.01 |
6 | 水 | 10.0μg/ml | 68.0 | 1.0 | p<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比(DMSO) | 0 | 100.0 | 1.0 | |
0 | 5α-Avocuta | 0.1% | 82.4 | 1.6 | P<0.01 |
0 | AsebiolTM | 0.1% | 82.4 | 2.7 | P<0.01 |
9 | EtAc | 0.1μg/ml | 92.2 | 1.3 | P<0.05 |
10 | EtAc | 1.0μg/ml | 77.1 | 0.6 | P<0.01 |
11 | EtOH | 0.1μg/ml | 87.1 | 2.3 | P<0.01 |
12 | EtOH | 1.0μg/ml | 80.5 | 1.3 | P<0.01 |
13 | 水 | 0.1μg/ml | 81.4 | 2.0 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比(DMSO) | 0 | 100.0 | 1.7 | |
0 | 辣椒素 | 0 | 68.5 | 1.5 | P<0.01 |
14 | K–EtOH | 0.1μg/ml | 60.6 | 2.3 | P<0.01 |
15 | K–EtOH | 10μg/ml | 59.3 | 1.2 | P<0.01 |
16 | M–EtOH | 0.1μg/ml | 71.3 | 2.3 | P<0.01 |
17 | M–EtOH | 10μg/ml | 65.4 | 1.3 | P<0.01 |
18 | C–EtOH | 0.1μg/ml | 54.1 | 1.0 | P<0.01 |
19 | C–EtOH | 10μg/ml | 53.6 | 0.3 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比(DMSO) | 0 | 100.0 | 1.1 | |
0 | 辣椒素 | 0 | 59.2 | 0.7 | P<0.01 |
20 | K–EtOH | 0.1μg/ml | 58.0 | 1.2 | P<0.01 |
21 | K–EtOH | 10μg/ml | 59.2 | 0.9 | P<0.01 |
22 | M–EtOH | 0.1μg/ml | 67.9 | 0.9 | P<0.01 |
23 | M–EtOH | 10μg/ml | 52.8 | 0.6 | P<0.01 |
24 | C–EtOH | 0.1μg/ml | 56.1 | 0.5 | P<0.01 |
25 | C–EtOH | 10μg/ml | 64.8 | 0.9 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比 | 0 | 100.0 | 1.8 | |
0 | 辣椒素 | 0 | 91.9 | 1.5 | P<0.05 |
30 | ES–水 | 0.1μg/ml | 82.8 | 1.2 | P<0.01 |
31 | ES–水 | 10μg/ml | 87.5 | 1.8 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比 | 0 | 100.0 | 3.1 | |
32 | ES-EtOH | 0.1μg/ml | 114.0 | 2.9 | P<0.01 |
33 | ES-EtOH | 10μg/ml | 101.9 | 2.9 | n.s. |
34 | IC–EtOH | 10μg/ml | 71.8 | 1.1 | P<0.01 |
35 | IC–water | 0.1μg/ml | 87.5 | 1.9 | P<0.01 |
36 | IC–water | 10μg/ml | 80.3 | 1.4 | P<0.01 |
37 | SF-MeOH | 0.1μg/ml | 86.3 | 1.0 | P<0.01 |
38 | SF–MeOH | 10μg/ml | 76.1 | 1.9 | P<0.01 |
39 | SV–MeOH | 0.1μg/ml | 78.8 | 1.3 | P<0.01 |
40 | SV–MeOH | 10μg/ml | 73.6 | 1.6 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比 | 0 | 100.0 | 0.8 | |
0 | 辣椒素 | 5μM | 62.9 | 0.4 | P<0.01 |
41 | SF–EtOH | 0.1μg/ml | 91.8 | 1.2 | P<0.01 |
42 | SF–EtOH | 10μg/ml | 83.1 | 1.0 | P<0.01 |
43 | SV–EtOH | 0.1μg/ml | 60.4 | 0.3 | P<0.01 |
44 | SV–EtOH | 10μg/ml | 92.3 | 0.8 | P<0.01 |
实施例 | 样本 | 含量 | 均值 | 标准误差 | 统计显著性 |
0 | 对比 | 0 | 100.0 | 1.4 | |
0 | SF–水 | 0.1μg/ml | 116.7 | 4.3 | P<0.01 |
45 | SF–水 | 10μg/ml | 106.6 | 3.4 | n.s. |
46 | SV–水 | 0.1μg/ml | 88.1 | 2.8 | P<0.05 |
47 | SV–水 | 10μg/ml | 95.4 | 2.3 | n.s. |
48 | SV–EtOH | 0.1μg/ml | 81.8 | 1.4 | P<0.01 |
49 | SV–EtOH | 10μg/ml | 83.7 | 1.5 | P<0.01 |
50 | ES–EtOH | 0.1μg/ml | 155.6 | 5.3 | P<0.01 |
51 | ES–EtOH | 10μg/ml | 123.8 | 1.3 | P<0.01 |
52 | K–水 | 0.1μg/ml | 132.2 | 2.5 | P<0.01 |
53 | K–水 | 10μg/ml | 106.9 | 2.4 | n.s. |
Claims (13)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14179936 | 2014-08-05 | ||
EP14179936.1 | 2014-08-05 | ||
PCT/EP2015/067860 WO2016020339A2 (en) | 2014-08-05 | 2015-08-03 | Extracts of microalgae and plants for regulating sebum production |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106659674A true CN106659674A (zh) | 2017-05-10 |
Family
ID=51265605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201580042070.6A Pending CN106659674A (zh) | 2014-08-05 | 2015-08-03 | 用于调节皮脂分泌的微藻和植物提取物 |
Country Status (4)
Country | Link |
---|---|
US (2) | US10695387B2 (zh) |
EP (1) | EP3177305B1 (zh) |
CN (1) | CN106659674A (zh) |
WO (1) | WO2016020339A2 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109799270A (zh) * | 2019-02-18 | 2019-05-24 | 蔡涛 | 一种能有效提高对乙醇气体响应性能的敏感膜 |
CN111787935A (zh) * | 2018-02-28 | 2020-10-16 | 西姆莱斯股份公司 | 扁藻提取物 |
CN117298198A (zh) * | 2023-10-16 | 2023-12-29 | 山东悦翔生物有限公司 | 一种微藻的提取物应用于医疗的方法 |
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KR101922245B1 (ko) * | 2016-05-04 | 2018-11-27 | 주식회사 파이토코퍼레이션 | 염생식물 유래의 기능성이 강화된 탈염 영양 조성물과 그 제조방법 |
EP3562474A4 (en) * | 2017-01-01 | 2020-08-19 | Khalifa University of Science and Technology | COMPOSITIONS BASED ON HALOPHYTE PLANTS, AND METHODS OF USING THE LATTER |
IT201700090929A1 (it) * | 2017-08-07 | 2019-02-07 | Cutech S R L | Usi cosmetici e medici di estratti del fungo Coprinus comatus per la regolazione dell’unità pilo sebacea. |
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WO2023128883A1 (en) * | 2021-12-27 | 2023-07-06 | Yildiz Tekni̇k Üni̇versi̇tesi̇ | Composition containing microalgae extract for use in the treatment of seborrheic dermatitis |
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JP2010013373A (ja) * | 2008-07-02 | 2010-01-21 | Pola Chem Ind Inc | 角層細胞強化に好適な化粧料。 |
CN106176348A (zh) * | 2011-04-06 | 2016-12-07 | 玫琳凯有限公司 | 局部皮肤用组合物及处理皮肤的方法 |
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CN111787935A (zh) * | 2018-02-28 | 2020-10-16 | 西姆莱斯股份公司 | 扁藻提取物 |
CN109799270A (zh) * | 2019-02-18 | 2019-05-24 | 蔡涛 | 一种能有效提高对乙醇气体响应性能的敏感膜 |
CN117298198A (zh) * | 2023-10-16 | 2023-12-29 | 山东悦翔生物有限公司 | 一种微藻的提取物应用于医疗的方法 |
CN117298198B (zh) * | 2023-10-16 | 2024-03-01 | 山东悦翔生物有限公司 | 一种微藻的提取物及其应用 |
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US10695387B2 (en) | 2020-06-30 |
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WO2016020339A3 (en) | 2016-03-31 |
US20200353023A1 (en) | 2020-11-12 |
US11576938B2 (en) | 2023-02-14 |
US20170224751A1 (en) | 2017-08-10 |
EP3177305A2 (en) | 2017-06-14 |
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