CN106623204A - ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method - Google Patents

ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method Download PDF

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Publication number
CN106623204A
CN106623204A CN201710084043.6A CN201710084043A CN106623204A CN 106623204 A CN106623204 A CN 106623204A CN 201710084043 A CN201710084043 A CN 201710084043A CN 106623204 A CN106623204 A CN 106623204A
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CN
China
Prior art keywords
elisa plate
cleaning
lid
box body
plate
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Pending
Application number
CN201710084043.6A
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Chinese (zh)
Inventor
吴建国
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Individual
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Individual
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Priority to CN201710084043.6A priority Critical patent/CN106623204A/en
Publication of CN106623204A publication Critical patent/CN106623204A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Cleaning By Liquid Or Steam (AREA)

Abstract

The invention relates to an ELISA plate board cleaning machine provided with an automatic board beating device and a matched board cleaning method. The invention aims at solving the problem that people need to be involved in the prior art of board cleaning. The ELISA plate board cleaning machine comprises a box body and a cover body which sheathe each other, an ELISA plate placing cavity is arranged in the cover body, through holes with corresponding amount and size are formed corresponding to plate holes of the ELISA plate, an ELISA plate cleaning device is arranged in the box body, and the automatic board beating device is also arranged on the board cleaning machine; and the automatic board beating device comprises a power source and an intermittent vibration mechanism in control connection with the power source. The ELISA plate board cleaning machine provided by the invention has the beneficial effects that cleaning and board beating are integrated into a whole, the degree of automation is high, cleaning and swinging speed is high, and labour is saved.

Description

ELISA plate washing machine and supporting plate washing method with clappers device automatically
Technical field
The present invention relates to immunity inspection detection cleaning equipment, particularly a kind of ELISA plate washing with clappers device automatically Machine and supporting plate washing method.
Background technology
Enzyme linked immunological chemical experiment is widely used in the research of the multi-door subject such as medical science, biology and detection work. Need to change different reaction substrates in the immunoreaction process, therefore the cleaning as reaction vessel ELISA Plate just becomes instead Should Jing steps.
In enzyme linked immunological experiment and detection process, often by the use of ELISA Plate as reaction vessel and zymophore.During experiment Often add in each micropore by reaction reagent and by experiment sample, reacted in the environment of simulation human body temperature.Question response Reactant in the ELISA Plate micropore not reacted is washed away after end, is stayed and is reacted and combine the thing on micro-pore wall Matter, this process is referred to as board-washing.Just other reaction substrates can be added after board-washing, the experimentation of next step is carried out.Present each reality The board-washing process for testing room is typically completed in two steps, and the first step is to inject washing lotion repeatedly in micropore to be cleaned;Second step is clear Except the residual washing lotion in micropore;This step often needs experiment technical personnel manpower to have the final say, minimum to ensure micropore residual washing lotion.
Researcher is in long-term work it has been observed that either usually being needed using artificial board-washing or machine board-washing Manpower intervention, not only affects operating efficiency, and causes potential bio-safety hidden danger.
The content of the invention
The purpose of the present invention is exactly to solve the problems, such as that existing board-washing needs artificial participation, making whole board-washing process higher Effect, it is safer.The present invention provides a kind of energy in ELISA Plate cleaning process board-washing, the equipment of automatic clappers automatically.
To solve above-mentioned technical problem, the concrete scheme of the present invention is:
A kind of ELISA plate washing machine with clappers device automatically, including the box body and lid that are mutually set with, is provided with enzyme mark in lid The plate hole of plate placed cavity and correspondence ELISA Plate is provided with the corresponding through hole of number size, and ELISA Plate cleaning is provided with the box body Device, is additionally provided with clappers device automatically on the board-washing machine;The automatic clappers device includes power source and the power source control The intermittent percussion mechanism of system connection.
Preferably, the automatic clappers device is arranged on box body, including fulcrum is located at the lever and power above box body The intermittent drive that source drives, one end of the lever is provided with to tinker with uses counterweight, and the other end is in the intermittent transmission The lower section of wheel, is provided with fixation balladeur train between the box body and lid, fixation balladeur train or the lid are provided between box body and lid The hinged connection between box body.
Further, the intermittent rotating wheel includes annulus drive, is provided with the cylinder of the circular drive At least two arcuation driver plates for stretching out, the driver plate is tangent with the cylinder.
Or, the automatic clappers device includes being arranged on the support of fixed intermittence percussion mechanism on box body, it is described between Having a rest property percussion mechanism includes that the cross section that motor is driven is meniscate power transmission shaft, the lifting by power transmission shaft drive upwards Bar and the reset element that the elevating lever resets is driven when drive axis are to relevant position;The lid is fixed on elevating lever On, so that the elevating lever is able to drive lid movement.Hinged connection between lid and elevating lever.
Again or, the automatic clappers device is installed on the lid, including motor drive crank and rocker mechanism, its The hammer that vibrates is provided with below middle rocking bar, the box body is provided with carries out spacing spacing bucket to the hammer in-plane that vibrates.
Or, the automatic clappers device includes the balladeur train of fixed lid and suction on the lid being installed on the balladeur train Attached plate, is provided with electromagnetic adsorption element between the lid and the adsorption plate and elastic force gets rid of clearly element, one end of the balladeur train and institute State adsorption plate on lid to fix, the other end is fixed on box body.
Preferably, the ELISA Plate cleaning device includes cleaning sprayer corresponding with each through hole and is connected with cleaning sprayer Cleaning fluid liquid source.
A kind of plate washing method of the ELISA Plate being related to, using above-mentioned ELISA plate washing machine, comprises the steps:
(1)Dispose and position:ELISA Plate is installed on into the specified location in cleaning chamber, thereon each test hole lower section correspondence sets There is the delivery port of cleaning device;
(2)Cleaning:External cleaning fluid liquid source, a length of 5 when being carried out with hole by each test of the cleaning device to ELISA Plate The cleaning of~55s, the current direction Jing lower sections outlet pipe after cleaning flows out;
(3)Knockout plate:The intermittent knockout plate of 3 to 5 times is carried out to the cover plate that ELISA Plate is located using clappers device automatically, clear remnants are got rid of Moisture content.
The beneficial effects of the present invention is:
(1)A set of full-automatic instrument for integrating cleaning, having the final say is devised, without the need for manpower intervention in whole process, automation Degree is high, and clearance time is short, further avoids later stage cross-infection;
(2)Clappers device structure is simple, the timing vibrating to associated cleaning equipment is completed by intermittent movement, further to complete The process of knockout plate, the time is short, and momentum is big, is conveniently adjusted in later stage work and maintenance;
(3)Overall volume is little, is easy to transition and carries, wherein, plate beating mechanism can individually work independently, and adapt to various operation machines The board-washing machine of structure.
Description of the drawings
Fig. 1 is that the axle of a certain embodiment of the invention surveys direction structure schematic diagram;
Fig. 2 is the main view direction structure schematic diagram of structure shown in Fig. 1;
Fig. 3 be in Fig. 2 C to sectional view;
Fig. 4 be in Fig. 3 box portion D to sectional view;
Fig. 5 is the overlook direction structural representation of structure shown in Fig. 1;
Fig. 6 is the side-looking direction sectional view of structure shown in Fig. 1;
Fig. 7 is that the axle of another embodiment of the present invention surveys direction schematic diagram;
Fig. 8 is the main view direction structure schematic diagram of structure shown in Fig. 7;
Fig. 9 is the left view direction structure schematic diagram of structure shown in Fig. 7;
Figure 10 is the overlook direction structural representation of structure shown in Fig. 7;
Figure 11 is the principle schematic of the device of clappers automatically of the invention;
Figure 12 is that the axle of yet another embodiment of the invention surveys direction structure schematic diagram;
Figure 13 is the main view direction structure schematic diagram of structure shown in Figure 12;
Figure 14 is the left view direction structure schematic diagram of structure shown in Figure 12;
Figure 15 is the overlook direction structural representation of structure shown in Figure 12;
Figure 16 is the present invention and the axle of another embodiment surveys direction structure schematic diagram;
Figure 17 is the main view direction structure schematic diagram of structure shown in Figure 16;
Figure 18 be the present invention again or an embodiment drive mechanism schematic diagram;
Each component names in figure:1. box body;2. lid;3. ELISA Plate placed cavity;4. ELISA Plate;5. through hole;6. cleaning needle;7. clear Board-washing;9. outlet pipe;10. valve;11. water inlet pipes;12. chutes;13. slide blocks;14. cleaning bottom cavities;15. power sources;16. Lever;17. intermittent drives;18. counterweights;19. balladeur trains;20. supports;21. power transmission shafts;22. elevating levers;23. reset elements; 24. rocking bars;25. spacing buckets;26. cranks;Adsorption plate on 27. lids;28. elastic force get rid of clearly element;29. electromagnetic adsorption elements;30. Gripper shoe.
Specific embodiment
Embodiment 1:A kind of ELISA plate washing machine with clappers device automatically, referring to Fig. 1 to Fig. 6, including what is be mutually set with Box body 1 and lid 2, the plate hole of ELISA Plate placed cavity 3 and correspondence ELISA Plate 4 is provided with lid 2, and to be provided with number size corresponding The cleaning device of ELISA Plate 4 is provided with through hole 5, box body 1, clappers device automatically is additionally provided with board-washing machine;Automatically clappers device includes Power source 15 and the intermittent percussion mechanism of the control connection of power source 15.
Specifically, in the present embodiment, automatically clappers device is arranged on box body 1, including fulcrum is located at the thick stick of the top of box body 1 The intermittent drive 17 that bar 16 and power source 15 drive, one end of lever 16 is provided with tinkers with counterweight 18, and the other end is in The lower section of intermittent drive 17, is provided with fixation balladeur train 19 between box body and lid.
Intermittent rotating wheel includes annulus drive, is provided with least two in the cylinder of circular drive and stretches out Arcuation driver plate, driver plate is tangent with cylinder.
Intermittent rotating wheel includes annulus drive, is provided with least two in the cylinder of circular drive and stretches out Arcuation driver plate, driver plate is tangent with cylinder.
ELISA Plate cleaning device includes the cleaning fluid liquid being connected with the corresponding cleaning sprayer of each through hole 5 and with cleaning sprayer Source.
When work starts, lid vertical display ELISA Plate to insert rotate lid after ELISA Plate placed cavity down from above, Cleaned with reference to box body afterwards, knockout plate is carried out after cleaning process terminates, or lid through hole is put upward, correspondence insertion lid Again overall upset is placed in box body top after body, by carriage supports.
A kind of plate washing method of ELISA Plate, using ELISA plate washing machine, comprises the steps:
(1)Dispose and position:ELISA Plate 4 is installed on into the specified location in cleaning chamber, thereon each test hole lower section correspondence It is provided with the delivery port of cleaning device;
(2)Cleaning:External cleaning fluid liquid source, a length of 15s when being carried out with hole by each test of cleaning device to ELISA Plate 4 Cleaning, the current direction Jing lower sections outlet pipe 9 after cleaning flows out;
(3)Knockout plate:The intermittent knockout plate of 3 to 5 times is carried out to the cover plate that ELISA Plate 4 is located using clappers device automatically, gets rid of clear residual Remaining moisture content.
The cleaning process entirety time can be foreshortened to 15s by the design, meanwhile, different from centrifugation knockout plate conventional at this stage Upwards, method involved in the present invention plate hole in cleaning and knockout plate is downward, it is to avoid cross-infection between plate hole for plate hole.
Embodiment 2, working method is with embodiment 1, concrete difference, referring to Fig. 7 to Figure 11, device of having the final say automatically Including the support 20 of the fixed intermittence percussion mechanism on box body 1, intermittent percussion mechanism includes the horizontal stroke that motor is driven Section is meniscate power transmission shaft 21, be transmitted axle 21 drives elevating lever 22 upwards and when drive axis are to relevant position The reset element 23 for driving elevating lever 22 to reset;Lid is fixed on elevating lever, so that elevating lever 22 is able to drive lid 2 to move It is dynamic.In the course of work, by the interaction of power transmission shaft and reset element, the vibrations of lid are driven, cut with scissors between lid and elevating lever Connection is propped up, when work starts, lid vertical display, ELISA Plate to insert rotate lid after ELISA Plate placed cavity down from above, Cleaned with reference to box body afterwards, after cleaning process terminates, intermittent percussion mechanism is started working, and carries out knockout plate.
Embodiment 3, with embodiment 1, concrete difference is working method, and referring to Figure 12 to Figure 15, automatically clappers are filled Put and be installed on lid 2, including the crank and rocker mechanism that motor drives, the lower section of wherein rocking bar 24 is provided with the hammer that vibrates, on box body 1 Be provided with carries out spacing spacing bucket 25 to the hammer in-plane that vibrates.
Embodiment 4, with embodiment 1, concrete difference is working method, and referring to Figure 16 to Figure 17, automatically clappers are filled The balladeur train 19 and adsorption plate 27 on the lid being installed on balladeur train 19 including fixed lid 2 is put, between lid 2 and adsorption plate electricity is provided with Magnetic suck element 29 and elastic force get rid of clearly element 28, and one end and the adsorption plate on lid 27 of balladeur train are fixed, and the other end is fixed on box body 1 On.
Embodiment 5, working method is that lid 2 is provided with intermittent vibrator with embodiment 1, concrete difference.Knot Structure is simple, is easy to maintenance and changes.
Embodiment 6, working method is that ELISA Plate is set in gripper shoe 30 with embodiment 2, concrete difference, Fagging 30 is installed in lead column, and gripper shoe is provided with the hinged connection that can adjust ELISA Plate angle, makes the ELISA Plate when getting rid of clearly Level, vertically takes out when picking and placeing, and getting rid of clearly for the present embodiment is main by being connected with the crescent projection of motor and adjusting gripper shoe The back-moving spring of position, in real work, back-moving spring can be set in lead column, it is also possible to installed in other equivalent substitutes Position on.
It is last it should be noted that, above person is only section Example of the present invention, and is not used to limit the present invention, according to this Bright structure and feature, slightly modifications and winner, also should be included within the scope of the present invention.

Claims (10)

1. a kind of ELISA plate washing machine with automatically clappers device, it is characterised in that:Including the box body being mutually set with(1)And lid (2), lid(2)Inside it is provided with ELISA Plate placed cavity(3)And correspondence ELISA Plate(4)Plate hole to be provided with number size corresponding logical Hole(5), the box body(1)Inside it is provided with ELISA Plate(4)Cleaning device, is additionally provided with clappers device automatically on the board-washing machine;It is described Automatically clappers device includes power source(15)With the power source(15)The intermittent percussion mechanism of control connection.
2. as claimed in claim 1 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The automatic clappers Device is arranged on box body(1)On, including fulcrum is positioned at box body(1)The lever of top(16)And power source(15)The intermittence of drive Drive(17), the lever(16)One end be provided with to tinker with and use counterweight(18), the other end is in the intermittent drive (17)Lower section.
3. as claimed in claim 2 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The box body and lid Fixation balladeur train is provided between body(19)Or hinged connection between the lid and box body.
4. as claimed in claim 2 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:Described intermittent turn Driving wheel includes annulus drive, and in the cylinder of the circular drive at least two arcuation driver plates for stretching out are provided with, The driver plate is tangent with the cylinder.
5. as claimed in claim 1 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The automatic clappers Device includes being arranged on box body(1)The support of upper fixed intermittence percussion mechanism(20), the intermittent percussion mechanism includes electric The cross section that machine is driven is meniscate power transmission shaft(21), by the power transmission shaft(21)Drive elevating lever upwards(22)With work as The elevating lever is driven when drive axis are to relevant position(22)The reset element of reset(23);The lid is fixed on lifting On bar, so that the elevating lever(22)It is able to drive lid(2)It is mobile.
6. as claimed in claim 5 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The lid and liter Hinged connection between drop bar.
7. as claimed in claim 1 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The automatic clappers Device is installed on the lid(2)On, including the crank and rocker mechanism that motor drives, wherein rocking bar(24)Lower section be provided with and vibrate Hammer, the box body(1)Be provided with carries out spacing spacing bucket to the hammer in-plane that vibrates(25).
8. as claimed in claim 1 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The automatic clappers Device includes fixed lid(2)Balladeur train(19)Be installed on the balladeur train(19)On lid on adsorption plate(27), the lid Body(2)Electromagnetic adsorption element is provided with between the adsorption plate(29)Element is got rid of clearly with elastic force(28), one end of the balladeur train and institute State adsorption plate on lid(27)Fixed, the other end is fixed on box body(1)On.
9. as claimed in claim 1 with the ELISA plate washing machine of clappers device automatically, it is characterised in that:The ELISA Plate is clear Cleaning device includes and each through hole(5)Corresponding cleaning sprayer and the cleaning fluid liquid source being connected with cleaning sprayer.
10. a kind of plate washing method of ELISA Plate, using ELISA plate washing machine as claimed in claim 1, it is characterised in that include Following steps:
(1)Dispose and position:By ELISA Plate(4)The specified location being installed in cleaning chamber, thereon each test hole lower section is right The delivery port of cleaning device should be provided with;
(2)Cleaning:External cleaning fluid liquid source, by the cleaning device to ELISA Plate(4)Each test carry out duration with hole For the cleaning of 5~55s, the current direction Jing lower sections outlet pipe after cleaning(9)Flow out;
(3)Knockout plate:Using clappers device automatically to ELISA Plate(4)The cover plate at place carries out the intermittent knockout plate of 3 to 5 times, gets rid of clear Remaining moisture content.
CN201710084043.6A 2017-02-16 2017-02-16 ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method Pending CN106623204A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710084043.6A CN106623204A (en) 2017-02-16 2017-02-16 ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710084043.6A CN106623204A (en) 2017-02-16 2017-02-16 ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method

Publications (1)

Publication Number Publication Date
CN106623204A true CN106623204A (en) 2017-05-10

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CN201710084043.6A Pending CN106623204A (en) 2017-02-16 2017-02-16 ELISA plate board cleaning machine provided with automatic board beating device and matched board cleaning method

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1612561A1 (en) * 2004-07-02 2006-01-04 Roche Diagnostics GmbH Instrument for efficient treatment of analytical devices
CN202008481U (en) * 2011-03-23 2011-10-12 杭州埃夫朗生化制品有限公司 Multifunctional plate washing machine
CN202155327U (en) * 2011-05-18 2012-03-07 闫国超 ELISA plate washing machine
CN203786121U (en) * 2014-01-27 2014-08-20 北京亦庄国际诊断试剂技术有限公司 Automatic plate beating machine for enzyme-linked immunosorbent assay
CN204544895U (en) * 2014-10-31 2015-08-12 西南大学 A kind of floating seedling tray reciprocating vibrating type cleaning equipment
CN205797861U (en) * 2016-06-23 2016-12-14 郑州和济生物科技股份有限公司 A kind of full-automatic ELIAS microplate washer
CN206613779U (en) * 2017-02-16 2017-11-07 吴建国 ELISA plate washing machine with automatic clappers device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1612561A1 (en) * 2004-07-02 2006-01-04 Roche Diagnostics GmbH Instrument for efficient treatment of analytical devices
CN202008481U (en) * 2011-03-23 2011-10-12 杭州埃夫朗生化制品有限公司 Multifunctional plate washing machine
CN202155327U (en) * 2011-05-18 2012-03-07 闫国超 ELISA plate washing machine
CN203786121U (en) * 2014-01-27 2014-08-20 北京亦庄国际诊断试剂技术有限公司 Automatic plate beating machine for enzyme-linked immunosorbent assay
CN204544895U (en) * 2014-10-31 2015-08-12 西南大学 A kind of floating seedling tray reciprocating vibrating type cleaning equipment
CN205797861U (en) * 2016-06-23 2016-12-14 郑州和济生物科技股份有限公司 A kind of full-automatic ELIAS microplate washer
CN206613779U (en) * 2017-02-16 2017-11-07 吴建国 ELISA plate washing machine with automatic clappers device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
汝元功等: "《机械设计手册》", 31 December 1995, 高等教育出版社 *

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