CN106620615A - Drug used for treating xeronosus, and preparation method thereof - Google Patents

Abstract

The invention discloses a drug used for treating xeronosus, and a preparation method thereof. The drug is mainly prepared from radix rehmanniae, angelica sinensis, radix scrophulariae, rhizoma coptidis, cortex phellodendri, radix astragali, radix asparagi, radix ophiopogonis, rhizoma polygonati, semen sesami nigrum, lilium brownie, flos chrysanthemi, radix adenophorae, and mulberry at a certain weight ratio. The drug is capable of clearing heat and cooling blood, nourishing yin and moistening dryness, and promoting the production of body fluid to quench thirst; when the drug is used for treating xeronosus, effect is achieved quickly, curative effect is excellent, and no side effect is caused.

Description

One kind treats xerotic medicine and preparation method thereof

Technical field

The present invention relates to one kind treats xerotic medicine and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Axersises, are a kind of connective tissue diseases with keratitis sicca and stomatitis as main clinical manifestation.Common sympton There are eye dry, xerostomia, lossless, big dry stool etc., it is also possible to involve the multiple systems of whole body.Because Western medicine effectively fast treating cannot be dried Disease, therefore there is great demand to the xerotic Chinese medicine of effectively treatment in people, up to now, it has not been found that with regard to this The relevant report of invention.

The content of the invention

The present inventor have found effectively treatment drying finally according to the checking repeatedly of research and the clinical trial of theory of Chinese medical science The medicine of disease, so as to complete the present invention.

It is an object of the invention to provide one kind more effectively treats xerotic Chinese medicine composition.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention is to select Radix Rehmanniae, Radix Angelicae Sinensis, Radix Scrophulariae, Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Asparagi, Radix Ophiopogonis, Rhizoma Polygonati, black Semen Sesami, Bulbus Lilii, Flos Chrysanthemi, Radix Adenophorae, Fructus Mori, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Fructus Aurantii Immaturus, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Rhizoma Zingiberis Recenss, Fructus Jujubae, Flos Osmanthi Fragrantis, mountain Zhu Cornel, Semen Persicae, Semen Platycladi, Poria, Herba Asari, Radix Saposhnikoviae, Seem Lablab Album, Radix Trichosanthis, Rhizoma Polygonati Odorati crude drug are combined preparation, by these medicines Combination causes each efficacy of drugs to produce synergism such that it is able to effectively treatment axersises.Wherein it is because it from Radix Rehmanniae Nature and flavor are sweet, tremble with fear, and GUIXIN, liver and kidney channel have clearing away heat and cooling blood, and yin nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency labor Heat, Heat Diabetes is spitted blood, epistaxis, spot dermexanthesis.Its nature and flavor sweet, acrid, warm is because from Radix Angelicae Sinensis, enter the heart, liver, spleen channel have benefit Blood and blood, menstruction regulating and pain relieving, the function of moisturize laxation controls menoxenia, and amenorrhea stomachache ， mass in the abdomen knots are poly-, and metrorrhagia, headache due to deficiency of blood is dizzy Dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine is difficult just, weight, ulcer sores, incised wound, injury from falling down after bloody dysentery.It is because that its nature and flavor is bitter from Radix Scrophulariae, it is salty, It is cool, enter lung, kidney channel, there is YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances controls pyreticosis polydipsia, sends out speckle, hectic fever due to YIN-deficiency consumptive fever, and night sleeps not peaceful, from Antiperspirant night sweat, Tianjin hinder constipation, hematemesis and epistaxiss, laryngopharynx swelling and pain, carbuncle, scrofula.It is because that its nature and flavor is bitter from Rhizoma Coptidis, trembles with fear, enter the heart, Liver, stomach, large intestine channel, there is pathogenic fire purging, and dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacterium Dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis are told, are defeated in battle, hematochezia, quenching one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, carbuncle Sore, eczema, the burning hot wound of soup.It is because that its nature and flavor is bitter from Cortex Phellodendri, trembles with fear, enter kidney, bladder warp, there is heat clearing away, dampness, pathogenic fire purging, solution The function of poison, controls hematodiarrhoea, has loose bowels, and quenches one's thirst, and jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid are had blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, mesh It is red to swell and ache, aphtha of the mouth and tongue, sore swollen toxin.It is because that its nature and flavor is sweet from the Radix Astragali, tepor enters lung, spleen channel, raw to defend solid with beneficial Table, inducing diuresis to remove edema, poison holding, the function of granulation promoting controls spontaneous perspiration, and night sweat, arthralgia due to stagnation of blood, edema, carbuncle is not burst or burst and holds back long；Process with there is invigorating middle warmer The function of QI invigorating, controls the disease of internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.From Tianmen Winter is because its nature and flavor sweetness and bitterness, trembles with fear, and enters lung, kidney channel, there is YIN nourishing, moisturizes, lung heat clearing, and the function of pathogenic fire reducing controls fever due to yin deficiency, and cough is told Blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain is quenched one's thirst, constipation.From its property sweet and slightly bitter taste is because Radix Ophiopogonis, tremble with fear, enter lung, stomach, heart channel, have Nourishing YIN and moistening the lung, relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, clearly Yearningly, calentura Tianjin wound, dry mouth and throat, constipation.Its property sweet taste is because from Rhizoma Polygonati, enters spleen, lung, kidney channel, there is invigorating the spleen and replenishing QI, moistened Cardiopulmonary, the function of bone and muscle strengthening, governance wasting cold and heat, tuberculosis hemoptysis, body void lack of appetite after being ill, muscles and bones is weak, rheumatalgia, wind favus Disease.From Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, put down, and Return liver, kidney, large intestine channel have invigorating the liver and kidney, and benefiting essence-blood, intestine moistening is dry Function, controls and feels dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dry constipation of intestines.It is because that its nature and flavor is sweet micro- from Bulbus Lilii Hardship, puts down, and enter the heart, lung meridian have a nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, controls pulmonary tuberculosis chronic cough, cough and spit expectorant blood, and waste heat is not clear after calentura, Dysphoria palpitates with fear, staring spells, beriberi edema.Its nature and flavor sweetness and bitterness is because from Flos Chrysanthemi, it is cool, enter lung, Liver Channel has dispelling wind, and disappear heat, Improving eyesight, the function of removing toxic substances controls headache, dizziness, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.It is because that its nature and flavor is sweet from Radix Adenophorae, It is slightly cold, attaches to the lung and stomach meridians, there is nourishing YIN and clearing away lung-heat, resolving sputum, the function of QI invigorating controls lung-heat type cough, and deficiency of YIN phthisical cough, dry cough expectorant is sticked, and gas is cloudy not Foot, restlessness and fever with thirst.It is because that its nature and flavor is sweet from Fructus Mori, trembles with fear, enter liver, kidney channel has tonifying liver, and kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., grows the function of liquid, Hepatic and renal YIN deficiency is controlled, is quenched one's thirst, constipation, mesh is dark, tinnitus, scrofula, articular instability.Be because that its nature and flavor is pungent from the Radix Angelicae Dahuricae, temperature, enter lung, Spleen, stomach, there is wind-dispelling, and dampness, detumescence, the function of pain relieving controls headache, supraorbital bone pain, toothache, nasal sinusitis, cold-dampness stomachache, hemorrhoidal hamorrhage hemorrhoid Leakage, leucorrhea with red and white discharge, ulcer sores, skin is dry itches, scabies.Be because its property sweet taste from Radix Glycyrrhizae, enter spleen, stomach, lung meridian, have and Middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription is processed with weakness of the spleen and stomach is controlled, and lack of appetite, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease is coughed Cough, cardiopalmus shy carbuncle, and raw with laryngopharynx swelling and pain is controlled, peptic ulcer, ulcer sores solve poison of drug and alimentary toxicosis.From Fructus Aurantii Immaturus be because It is bitter for its nature and flavor, tremble with fear, enter spleen, stomach, there is dispelling the stagnated QI, painful abdominal mass is dissipated, expectorant is rushed down, the function of removing food stagnancy controls chest and abdomen swelling and pain, the thoracic obstruction, painful abdominal mass pain, expectorant Addiction, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.It is because that its nature and flavor is bitter from Radix Bupleuri, cool, enter liver, gallbladder meridian have Reconciling superficies and interior, soothing the liver, the function of yang invigorating controls alternate attack of chill and fever, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, Menoxenia, uterine prolapse.It is because that its nature and flavor is pungent from Rhizoma Chuanxiong, temperature, enter liver, gallbladder meridian have activating QI to alleviate the depression, and dispeiling pathogenic wind and removing dampness is living The function of blood and relieving pain, controls air-cooled headache rotation and swoons, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, carbuncle skin ulcer Infectionss.Its nature and flavor picric acid is because from the Radix Paeoniae Alba, cool, enter liver, spleen channel have nourishing blood to suppress the hyperactive liver, pain relieving in delaying, yin fluid astringing receives the function of antiperspirant, Control chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.It is because from Rhizoma Zingiberis Recenss Nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, and cure cold wind and cold, and vomiting, phlegm retention is breathed with cough, Distension, has loose bowels, the solution Rhizoma Pinelliae, Rhizoma Arisaematiss and ichthyophagy crab, birds and beasts meat poisoning.It is because that its nature and flavor is sweet from Fructus Jujubae, temperature enters spleen, stomach, has Spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid adjusts battalion to defend, and solves the function of poison of drug, controls insufficiency of stomach lack of appetite, and the weak loose stool of spleen, qi-blood-body fluid is not enough, and battalion defends not With, severe palpitation, woman hysteria.It is because that its nature and flavor is pungent from Flos Osmanthi Fragrantis, temperature has resolving sputum, and the function of dissipating blood stasis controls phlegm and retained fluid is breathed with cough, Hemorrhoidal hamorrhage dysentery, hernia abdominal mass, toothache, halitosis.Its nature and flavor acid is because from Fructus Corni, tepor enters liver and kidney channel, there is invigorating the liver and kidney, arresting seminal emission Gas, Gu the function of collapse, controls soreness of waist and knee joint, dizziness, tinnitus, sexual impotence, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart Shake scattered pulse.Its nature and flavor bitter sweet is because from Semen Persicae, is put down, enter the heart, liver, large intestine channel have blood stasis removing and clots absorbing, moisturize the function of sliding Jing, Controlling through closing ， mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.It is because from Semen Platycladi Nature and flavor are sweet, put down, and enter the heart, liver, spleen channel have tranquilizing by nourishing the heart, and the function of loosening bowel to relieve constipation controls palpitation with fear, insomnia, seminal emission, night sweat, constipation Function.Its property slightly sweet flavor is because from Poria, is put down, enter the heart, spleen, lung meridian there are an eliminating dampness and diuresises, beneficial spleen and stomach, mind tranquilizing and the heart calming Function, controls dysuria edema distending pain, and phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.It is because from Herba Asari Its nature and flavor is pungent, temperature, enters lung, kidney channel, there is wind-dispelling, and cold expelling, water-filling is opened function surreptitiously, controls air-cooled headache, and nasal sinusitis, pain relieving, phlegm retention is coughed It is inverse, rheumatic arthralgia.Its property acrid-sweet flavor is because from Radix Saposhnikoviae, temperature enters bladder, lung, spleen channel, delivers, wind-dispelling, wins wet, pain relieving Function, control affection of exogenous wind-cold, have a headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, extremity contraction urgency, tetanus.It is from Seem Lablab Album Because its nature and flavor is sweet, put down, enter spleen, stomach, there is nvigorating the spleen and in, the function of removing dampness of relieving summer heat controls heat-damp in summer vomiting and diarrhoea, insufficiency of the spleen vomiting, lack of appetite Chronic diarrhea, water retention is quenched one's thirst, leucorrhea with red and white discharge, infantile malnutrition.Its nature and flavor sweetness and bitterness acid is because from Radix Trichosanthis, it is cool, enter lung, stomach, have Promote the production of body fluid, quench the thirst, pathogenic fire reducing is moisturized, evacuation of pus, the function of detumescence, it is thirsty to control calentura, quenches one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula. It is because that its nature and flavor is sweet from Rhizoma Polygonati Odorati, puts down, enter lung, stomach has yin nourishing, moisturizes, relieving restlessness, the function of quenching the thirst, control calentura sun wound, coughs Cough, excessive thirst, deficient fever, rapid digestion of food is easily hungry, frequent micturition.

Specific embodiment

The drug dose of instant component is also that inventor summarizes what is drawn through groping in a large number, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

20-30 gram of Radix Rehmanniae, 20-30 gram of Radix Angelicae Sinensis, 20-30 gram of Radix Scrophulariae, 3-4 gram of Rhizoma Coptidis, 4-6 gram of Cortex Phellodendri, 15-25 gram of the Radix Astragali, day 10-15 gram of winter of door, 15 grams of Radix Ophiopogonis, Rhizoma Polygonati 15-25,15-30 gram of Semen Sesami Nigrum, 10-20 gram of Bulbus Lilii, 10-20 gram of Flos Chrysanthemi, Radix Adenophorae 7- 9 grams, 10-20 gram of Fructus Mori, 6-8 gram of the Radix Angelicae Dahuricae, 3-5 gram of Radix Glycyrrhizae, 6-8 gram of Fructus Aurantii Immaturus, 6-10 gram of Radix Bupleuri, 2-4 gram of Rhizoma Chuanxiong, 4-8 gram of the Radix Paeoniae Alba, 2-3 gram of Rhizoma Zingiberis Recenss, 10-20 gram of Fructus Jujubae, 2-3 gram of Flos Osmanthi Fragrantis, 2-4 gram of Fructus Corni, 4-8 gram of Semen Persicae, 4-8 gram of Semen Platycladi, 5-7 gram of Poria, 5-7 gram of Herba Asari, 5-7 gram of Radix Saposhnikoviae, 3-4 gram of Seem Lablab Album, 2-4 gram of Radix Trichosanthis, 5-7 gram of Rhizoma Polygonati Odorati.

Preferably：

24 grams of Radix Rehmanniae, 24 grams of Radix Angelicae Sinensis, 24 grams of Radix Scrophulariae, 4 grams of Rhizoma Coptidis, 5 grams of Cortex Phellodendri, 20 grams of the Radix Astragali, 15 grams of Radix Asparagi, Radix Ophiopogonis 13 Gram, Rhizoma Polygonati 20,20 grams of Semen Sesami Nigrum, 15 grams of Bulbus Lilii, 15 grams of Flos Chrysanthemi, 8 grams of Radix Adenophorae, 15 grams of Fructus Mori, 7 grams of the Radix Angelicae Dahuricae, 4 grams of Radix Glycyrrhizae, trifoliate orange Real 7 grams, 8 grams of Radix Bupleuri, 2 grams of Rhizoma Chuanxiong, 6 grams of the Radix Paeoniae Alba, 3 grams of Rhizoma Zingiberis Recenss, 12 grams of Fructus Jujubae, 3 grams of Flos Osmanthi Fragrantis, 3 grams of Fructus Corni, 6 grams of Semen Persicae, cedar seed 6 grams of core, 6 grams of Poria, 6 grams of Herba Asari, 6 grams of Radix Saposhnikoviae, 4 grams of Seem Lablab Album, 3 grams of Radix Trichosanthis, 6 grams of Rhizoma Polygonati Odorati.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Radix Rehmanniae：Crude drug is taken, impurity is removed, is cleaned, slightly moistened, cut sheet, be dried, weed out chip；

2nd, Radix Angelicae Sinensis：Impurity is picked, is cleaned, moistening slightly dries in the air, and section is dried；

3rd, Radix Scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；

4th, Rhizoma Coptidis：Impurity is picked, silt particle is cleaned, is run through, cut into slices, dried in the shade；

5th, Cortex Phellodendri：Impurity is picked, is washed, pulled out, run through, cut into slices or shredding, dried；

6th, the Radix Astragali：Net impurity is picked, the root head and hollow larger root of residual is removed, is soaked in water, pulled out, cut in time after running through Piece, dries；

7th, Radix Asparagi：Impurity is picked, water is cleaned, and moistening to inside and outside humidity is uniform, cutting, drying；

8th, Radix Ophiopogonis：Net impurity is picked, is soaked in water, pulled out, pump the heart after running through, then cleaned and dry；

9th, Rhizoma Polygonati：Clean soil, slightly moistens, section, dries；

10th, Semen Sesami Nigrum：Crude drug is taken, impurity is removed, chip is weeded out；

11st, Bulbus Lilii：Pick impurity, black lobe, ash disposal of winnowing with a dustpan bits；

12nd, Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；

13rd, Radix Adenophorae：Fibrous root is removed, is cleaned, scrape off rough bark, be dried；

14th, Fructus Mori：Wash, pick impurity, extract long handle, dry；

15th, the Radix Angelicae Dahuricae：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after moistening, cut Piece is dried；

16th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；

17th, Fructus Aurantii Immaturus：Net impurity is picked, is soaked in water to eighty per cant thoroughly, pulled out, moistened to interior without hard-core, section, dried；

18th, Radix Bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries after running through；

19th, Rhizoma Chuanxiong：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after moistening, be dried；

20th, the Radix Paeoniae Alba：Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, moisten uniform to inside and outside humidity, Section, is dried；

21st, Rhizoma Zingiberis Recenss：Impurity is picked, soil, used time section is cleaned；

22nd, Fructus Jujubae：Net impurity is picked, is dried；

23rd, Flos Osmanthi Fragrantis：Harvest when the 9-10 months bloom, dry in the shade, pick impurity；

24th, Fructus Corni：Clean, except removal core and impurity, dry；

25th, Semen Persicae：Duricrust impurity is removed, is put in boiling water pot and is boiled to crust microcreping, pulled out, in immersion cold water, kind of a skin is removed in stranding, is shone It is dry, winnow with a dustpan net；

26th, Semen Platycladi：Net impurity is picked, the shell of residual is removed and is planted skin；

27th, Poria：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；

28th, Herba Asari：Cleared impurity, is moistened with water spray, and timely cutting is dried；

29th, Radix Saposhnikoviae：Residual stem is removed, is soaked in water, pulled out, run through section, dried；

30th, Seem Lablab Album：Pick net impurity, put in boiling water and slightly boil, to plant skin heave, it is soft for degree, pull out, immersion cold water in, slough skin, Dry；

31st, Radix Trichosanthis：Impurity is picked, size block is separate, pulled out with blister about sixty percent thoroughly, moistening to inside and outside humidity is uniform, cuts Piece, dries, or washes, and pulls out, shines to extremely dry, is pounded fritter；

32nd, Rhizoma Polygonati Odorati：Impurity is removed, soil is cleaned, moistening to inside and outside humidity is uniform, section is dried.

2nd, prepare

1st, by the Radix Rehmanniae of the weight, Radix Angelicae Sinensis, Radix Scrophulariae, Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Asparagi, Radix Ophiopogonis, Rhizoma Polygonati, Semen Sesami Nigrum, hundred Conjunction, Flos Chrysanthemi, Radix Adenophorae, Fructus Mori, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Fructus Aurantii Immaturus, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Rhizoma Zingiberis Recenss, Fructus Jujubae, Flos Osmanthi Fragrantis, Fructus Corni, Semen Persicae, Semen Platycladi, Poria, Herba Asari, Radix Saposhnikoviae, Seem Lablab Album, Radix Trichosanthis, Rhizoma Polygonati Odorati medicine are put in decocting container, are added water for the first time 8 times and are measured, immersion After 60 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 30 minutes, filter to obtain first time decoction liquor, first time decoction liquor is fallen Enter in container；

2nd, the medicinal residues of filtration are added water 6 times and is measured, boiled by intense fire, then with filtration in 20 minutes is cooked by slow fire, second decoction liquor is fallen Enter in container；

3rd, will decoction liquor mixing and stirring twice, obtain final product admixing medical solutions, be divided into 4 doses and take.

Radix Rehmanniae has clearing away heat and cooling blood, yin nourishing in prescription, and the function of promoting the production of body fluid is monarch drug；Radix Asparagi YIN nourishing, moisturizes, lung heat clearing, drop Fire, Radix Trichosanthis promote the production of body fluid, and quench the thirst, and pathogenic fire reducing is moisturized, evacuation of pus, and the two is ministerial drug for detumescence, and three taste medicines play promoting the production of body fluid to quench thirst, YIN nourishing jointly The effect moisturized, treatment axersises effect comprehensively, and based on nourshing Yin and drynsessmoistening prescription, can effect a permanent cure；Semen Platycladi tranquilizing by nourishing the heart, loosening bowel to relieve constipation For adjuvant drug；Radix Glycyrrhizae and middle emergency, lung moistening, removing toxic substances, to make medicine, all medicines are to take stopgap measures to coordinating the actions of various ingredients in a prescription with being left.

Medicine of the present invention has a clearing away heat and cooling blood, nourshing Yin and drynsessmoistening prescription, the function of promoting the production of body fluid to quench thirst, for treating axersises, short treating period, Instant effect, non-relapse after healing, have no toxic side effect.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples are including this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and 15 per group, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept axersises out-patient totally 40 for medical treatment.

2nd, diagnostic criteria

Clinically, more than 80% patient has dry mouth symptom, this is because salivary gland secretion reduce institute extremely, xerostomia without saliva or few saliva, Dryness food can not be swallowed, needs drinking-water just can swallow, go out to need band water.Most of patient is because salivary glands secrete saliva subtracts It is few, make tooth lose moistening, rinsing and Nutrition for saliva, so as to the gradually blackening of tooth body, and in bulk come off, finally only stay Undesirable root；Due to this dental caries generation and lesion degree it is serious far beyond general dental caries, therefore be referred to as " rampant carieses ".About 40% Patient once had the medical history of the both sides parotid gland alternately and repeatedly enlargement, and annual outbreak is multiple, and slightly flu or fatigue causes outbreak.Picture of the tongue Performance is respectively provided with following features：Tongue light purple is deep red, or dark red, light red, such as minute surface, or crackle is crisscross such as gully, without Tianjin without Tongue, tongue body cripetura is difficult to outside extending port.Because of lacrimal secretion function reduction, patient feels two dry and astringent, few tear or adacryas, and emotion swashs Also can not cry when dynamic tear, eye has foreign body abrasive feel, or burn feeling, and eyelid is heavy, feeling has at the moment tentiform to cover, photophobia, Ophthalmalgia, the angle of recurrent exerbation, conjunctivitis, severe patient can occur corneal nebula, perforation of cornea, uveitiss or front layer empyema, skin Skin is dried, and dryness in the nasal cavity is coughed and tell gluing expectorant, is hard and dry without tears, vaginal dryness, dyspareunia etc..

3rd, Therapeutic Method

From above-mentioned medicament, take to patient, 2 times a day, each take 1 dose, early daily, evening respectively takes 1 time, is a treatment within 15 days Journey, continuously takes the 2-4 course for the treatment of.

4th, efficacy assessment standard

It is effective：Disease symptoms disappearance is dried, recovery from illness, body constitution recovers normal；

Take a turn for the better：It is dried disease symptoms to be clearly better, parotid gland enlargement is eliminated, the performance of tongue picture tends to normal, and body constitution is progressively recovered；

It is invalid：Improvement standard person is not reached.

5th, therapeutic outcome（See the table below）

In above-mentioned treatment, with Drug therapy people with xerosis of the present invention 40, as a result effective 30, obvious effective rate is 75%, is taken a turn for the better 7, improvement rate is 17.5%, and invalid 3, total effective rate is 92.5%.

Claims (3)

1. one kind treats xerotic medicine, it is characterised in that：It is made up of the crude drug in following amount ranges：

20-30 gram of Radix Rehmanniae, 20-30 gram of Radix Angelicae Sinensis, 20-30 gram of Radix Scrophulariae, 3-4 gram of Rhizoma Coptidis, 4-6 gram of Cortex Phellodendri, 15-25 gram of the Radix Astragali, day 10-15 gram of winter of door, 15 grams of Radix Ophiopogonis, Rhizoma Polygonati 15-25,15-30 gram of Semen Sesami Nigrum, 10-20 gram of Bulbus Lilii, 10-20 gram of Flos Chrysanthemi, Radix Adenophorae 7- 9 grams, 10-20 gram of Fructus Mori, 6-8 gram of the Radix Angelicae Dahuricae, 3-5 gram of Radix Glycyrrhizae, 6-8 gram of Fructus Aurantii Immaturus, 6-10 gram of Radix Bupleuri, 2-4 gram of Rhizoma Chuanxiong, 4-8 gram of the Radix Paeoniae Alba, Rhizoma Zingiberis Recenss 2-3 pieces, 10-20 piece of Fructus Jujubae, 2-3 gram of Flos Osmanthi Fragrantis, 2-4 gram of Fructus Corni, 4-8 gram of Semen Persicae, 4-8 gram of Semen Platycladi, 5-7 gram of Poria, 5-7 gram of Herba Asari, 5-7 gram of Radix Saposhnikoviae, 3-4 gram of Seem Lablab Album, 2-4 gram of Radix Trichosanthis, 5-7 gram of Rhizoma Polygonati Odorati.

2. medicine according to claim 1, wherein the consumption of each crude drug is：

24 grams of Radix Rehmanniae, 24 grams of Radix Angelicae Sinensis, 24 grams of Radix Scrophulariae, 4 grams of Rhizoma Coptidis, 5 grams of Cortex Phellodendri, 20 grams of the Radix Astragali, 15 grams of Radix Asparagi, Radix Ophiopogonis 13 Gram, Rhizoma Polygonati 20,20 grams of Semen Sesami Nigrum, 15 grams of Bulbus Lilii, 15 grams of Flos Chrysanthemi, 8 grams of Radix Adenophorae, 15 grams of Fructus Mori, 7 grams of the Radix Angelicae Dahuricae, 4 grams of Radix Glycyrrhizae, trifoliate orange Real 7 grams, 8 grams of Radix Bupleuri, 2 grams of Rhizoma Chuanxiong, 6 grams of the Radix Paeoniae Alba, 3, Rhizoma Zingiberis Recenss, 12 pieces of Fructus Jujubae, 3 grams of Flos Osmanthi Fragrantis, 3 grams of Fructus Corni, 6 grams of Semen Persicae, cedar seed 6 grams of core, 6 grams of Poria, 6 grams of Herba Asari, 6 grams of Radix Saposhnikoviae, 4 grams of Seem Lablab Album, 3 grams of Radix Trichosanthis, 6 grams of Rhizoma Polygonati Odorati.

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Radix Rehmanniae：Crude drug is taken, impurity is removed, is cleaned, slightly moistened, cut sheet, be dried, weed out chip；

（2）Radix Angelicae Sinensis：Impurity is picked, is cleaned, moistening slightly dries in the air, and section is dried；

（3）Radix Scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；

（4）Rhizoma Coptidis：Impurity is picked, silt particle is cleaned, is run through, cut into slices, dried in the shade；

（5）Cortex Phellodendri：Impurity is picked, is washed, pulled out, run through, cut into slices or shredding, dried；

（6）The Radix Astragali：Net impurity is picked, the root head and hollow larger root of residual is removed, is soaked in water, pulled out, cut in time after running through Piece, dries；

（7）Radix Asparagi：Impurity is picked, water is cleaned, and moistening to inside and outside humidity is uniform, cutting, drying；

（8）Radix Ophiopogonis：Net impurity is picked, is soaked in water, pulled out, pump the heart after running through, then cleaned and dry；

（9）Rhizoma Polygonati：Clean soil, slightly moistens, section, dries；

（10）Semen Sesami Nigrum：Crude drug is taken, impurity is removed, chip is weeded out；

（11）Bulbus Lilii：Pick impurity, black lobe, ash disposal of winnowing with a dustpan bits；

（12）Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；

（13）Radix Adenophorae：Fibrous root is removed, is cleaned, scrape off rough bark, be dried；

（14）Fructus Mori：Wash, pick impurity, extract long handle, dry；

（15）The Radix Angelicae Dahuricae：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after moistening, cut Piece is dried；

（16）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；

（17）Fructus Aurantii Immaturus：Net impurity is picked, is soaked in water to eighty per cant thoroughly, pulled out, moistened to interior without hard-core, section, dried；

（18）Radix Bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries after running through；

（19）Rhizoma Chuanxiong：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after moistening, be dried；

（20）The Radix Paeoniae Alba：Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, moisten uniform to inside and outside humidity, Section, is dried；

（21）Rhizoma Zingiberis Recenss：Impurity is picked, soil, used time section is cleaned；

（22）Fructus Jujubae：Net impurity is picked, is dried；

（23）Flos Osmanthi Fragrantis：Harvest when the 9-10 months bloom, dry in the shade, pick impurity；

（24）Fructus Corni：Clean, except removal core and impurity, dry；

（25）Semen Persicae：Duricrust impurity is removed, is put in boiling water pot and is boiled to crust microcreping, pulled out, in immersion cold water, kind of a skin is removed in stranding, is shone It is dry, winnow with a dustpan net；

（26）Semen Platycladi：Net impurity is picked, the shell of residual is removed and is planted skin；

（27）Poria：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；

（28）Herba Asari：Cleared impurity, is moistened with water spray, and timely cutting is dried；

（29）Radix Saposhnikoviae：Residual stem is removed, is soaked in water, pulled out, run through section, dried；

（30）Seem Lablab Album：Pick net impurity, put in boiling water and slightly boil, to plant skin heave, it is soft for degree, pull out, immersion cold water in, slough Skin, dries；

（31）Radix Trichosanthis：Impurity is picked, size block is separate, pulled out with blister about sixty percent thoroughly, moistening to inside and outside humidity is uniform, cuts Piece, dries, or washes, and pulls out, shines to extremely dry, is pounded fritter；

（32）Rhizoma Polygonati Odorati：Impurity is removed, soil is cleaned, moistening to inside and outside humidity is uniform, section is dried；

（Two）Prepare

（1）By the Radix Rehmanniae of the weight, Radix Angelicae Sinensis, Radix Scrophulariae, Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Asparagi, Radix Ophiopogonis, Rhizoma Polygonati, Semen Sesami Nigrum, Bulbus Lilii, Flos Chrysanthemi, Radix Adenophorae, Fructus Mori, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Fructus Aurantii Immaturus, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Rhizoma Zingiberis Recenss, Fructus Jujubae, Flos Osmanthi Fragrantis, Fructus Corni, Fructus Persicae Core, Semen Platycladi, Poria, Herba Asari, Radix Saposhnikoviae, Seem Lablab Album, Radix Trichosanthis, Rhizoma Polygonati Odorati medicine are put in decocting container, are added water for the first time 8 times and are measured, After immersion 60 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 30 minutes, filter to obtain first time decoction liquor, first time is decocted Liquid is poured in container；

2nd, the medicinal residues of filtration are added water 6 times and is measured, boiled by intense fire, then with filtration in 20 minutes is cooked by slow fire, second decoction liquor is fallen Enter in container；

3rd, will decoction liquor mixing and stirring twice, obtain final product admixing medical solutions, be divided into 4 doses and take.