CN106619854A - External traditional Chinese medicine composition for treating haemorrhoids - Google Patents
External traditional Chinese medicine composition for treating haemorrhoids Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract
The invention relates to the field of medicines, particularly to a traditional Chinese medicine composition for treating haemorrhoids. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30-60 parts of rheum officinale, 5-30 parts of short-pedicel aconite roots, 20-30 parts of sanguisorba officinalis and 1-10 parts of musk. The traditional Chinese medicine composition is small in use amount, good in medicinal effect and stable in treatment effect, and the disease does not reoccur and can be treated at one time. Sanguisorba officinalis and musk can be added according to illness situations, so that the effects of removing swelling, relieving pain, stopping itching, stopping bleeding and enriching blood, of the composition can be further improved.
Description
Technical field
The present invention relates to field of medicaments, specifically with regard to a kind of external medicine composition for treating hemorrhoid.
Background technology
Medical science indication hemorrhoid include internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, are the venous plexuses generations of anal orifice and rectal intestine bottom and anal mucosa
Varicose and a kind of chronic disease of one or more soft venous groups for being formed, account for 87.25% in anorectal disorder.It is any
Age can all fall ill, but with age, sickness rate gradually increases." ten male nine hemorrhoid ", the saying of " ten female, ten hemorrhoid " are have, is led to
Often recurrent exerbation, is difficult to cure.The risk factor of hemorrhoid is a lot, wherein constipation, long-term alcohol, take food a large amount of irritable foods and
Sitting standing for a long time is main inducing.
The medicine of existing treatment hemorrhoid is mainly oral medicine and medicine for external use, and oral medicine reach again disease by digesting and assimilating
Stove, onset time are long, according to individual physique difference, assimilation effect also difference, and it is reduced to be actually reached affected area drug effect,
And it is big to internal organs burden to take oral medicine, so as to can also increase the hemorrhoid state of an illness, so tending to use external patient more
Medicine.
A kind of patent of invention " Chinese medicine composition of external for treating hemorrhoids " of Application No. 2007100165502, discloses
Hemorrhoid are treated using the medicine prepared containing Chinese medicines such as Radix Sanguisorbae, Rhizoma Coptidis, but which requires more than 10 days healing times, and needed auxiliary
Help injection treatment.
A kind of patent of invention " external wash liquid for treating hemorrhoid " of Application No. 2013107046336, discloses employing and contains
Drug therapy hemorrhoid prepared by the Chinese medicines such as Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, but which needs the treatment of two courses for the treatment of fully recover, and each course for the treatment of is needed
5 days are taken, and its cure rate only has 87.8%.
The content of the invention
Undesirable for hemorrhoid external medicine composition Cure, treatment time is long, the various problems such as relapse rate is higher,
The present invention intends providing a kind of external medicine composition for treating hemorrhoid, overcomes the above difficult, with healing time it is short, cure after not
The features such as recurrence (or relapse rate is extremely low).
Specifically, the invention provides a kind of Chinese medicine composition for treating hemorrhoid, its raw material includes following weight proportion
Component：Radix Et Rhizoma Rhei 30-60 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-30 parts.In a specific embodiment of the invention, the raw material weight proportioning of soup processed for using
For Radix Et Rhizoma Rhei 40-55 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 10-25 parts.
Further, the raw material also includes Radix Sanguisorbae 20-30 parts.In a specific embodiment of the invention, Radix Sanguisorbae consumption
For 25-30 parts.
Further, the raw material also includes Moschus 1-10 parts.In a specific embodiment of the invention, Radix Sanguisorbae consumption is
25-30 parts.Moschus of the present invention can also be replaced with artificial Moschuss.
Further, the raw material also includes Rhizoma Coptidis 10-30 parts, Radix Sophorae Flavescentiss 20-30 parts, Radix Rubiae 10-30 parts, Rhizoma Smilacis Glabrae
The mixture of one or more component in 20-50 parts, Borneolum Syntheticum 1-15 parts.In a specific embodiment of the invention, Rhizoma Coptidis are
20-25 parts, Radix Sophorae Flavescentiss are 25-30 parts, Radix Rubiae is 20-25 parts, Rhizoma Smilacis Glabrae is 30-40 parts, Borneolum Syntheticum is 4-10 parts.
Present invention also offers a kind of external medicine composition for treating hemorrhoid, component of its raw material by following weight proportion
Composition：Radix Et Rhizoma Rhei 30-60 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-30 parts.
External medicine composition of the present invention, its dosage form are unguentum, powder, suppository or lotion, it is also possible to other
The external preparation form for the treatment of hemorrhoid.In each preparation of the present invention, corresponding customary adjuvant can be used according to agents area, such as be planted
Thing oil, mineral oil, vaseline, gelatin etc..
Present invention also offers the preparation method of the external medicine composition of above-mentioned treatment hemorrhoid, it is by the proportioning
The mixing of the medicated powder of raw material, water extract or/and ethanol extract, is prepared into external preparation, obtains final product.
Wherein, ethanol extract uses alcohols solvent and extracts preparation, and conventional alcohols solvent has ethanol, methanol, propanol, but
The application of ethanol is more extensive, and toxic and side effects are low, is the choice solvent for preparing ethanol extract in the present invention.Ethanol extraction includes
Using dehydrated alcohol and aquiferous ethanol, the aquiferous ethanol that concentration of alcohol is 5-95% is used in general production process as molten more
Agent, especially 20-95%, such as 20-40% ethanol, 50-80% ethanol, 95% ethanol.
The preparation of water extract, can be in various traditional extraction modes such as employing decoction, backflow, ultrasound, microwave-assisted；Ethanol extract
Preparation, can with adopt backflow, ultrasound, microwave-assisted, impregnate, ooze various traditional extraction modes such as clear.But, the system of each extract
It is standby, it is not limited to aforesaid way.
Heretofore described medicated powder, including the powder of conventional particle size size, also including superfine powder, modern study shows ultra micro
Powder has abolished plant cell walls, is more beneficial for the dissolution of effective ingredient, contributes to improving bioavailability.
In addition, the raw material used in the present composition, is not limited to crude drug, suitable processed product can also be used, at this
On the basis of disclosure of the invention formula, those skilled in the art utilize general knowledge known in this field and normal experiment means, just can be
In the case of creative ability need not being spent, select or/and checking obtains one or more processed product of Suitable therapeutic hemorrhoid.
Present invention also offers above-mentioned Chinese medicine composition prepares the application in medicine for treaching hemorrhoie.
Above-mentioned Chinese medicine composition is added other adjuvants and makes unguentum, powder, suppository, water preparation by the present invention.
In a specific embodiment of the invention, it is that compositionss are prepared into into ointment, smears perianal or anus daily
1-2 time in door, it is within 3-5 days a course for the treatment of.
Radix Et Rhizoma Rhei is cold in nature, cures mainly heat-clearing and toxic substances removing, promoting blood circulation and detumescence, constipation, furuncle swelling toxin；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is warm in nature, cures mainly
Dehumidification swelling, innominate toxic swelling, analgesia disappear silt.Both compatibilities primarily serve heat-clearing and toxic substances removing, detumescence promoting blood circulation, analgesia and disappear silt, defecation
Effect, can directly using both compatibe drugs to suffering from the hemorrhoid time is short, hematochezia is not severe patient, the cure rate in the course for the treatment of
Up to 95%.The formula is equally applicable to the patient being in a bad way, but reduction of patient pain is longer with respect to needing in the short time
Time, a course cure rate can reach 90%.
Radix Sanguisorbae cold nature, cure mainly removing heat from blood pathogenic fire purging, bloody dysentery have blood in stool, incised wound bleeding；Moschus is warm in nature, cures mainly promoting flow of QI and blood, carbuncle
Sore, ulcerative carbuncle are rotten long.Using Radix Et Rhizoma Rhei and Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), and compounding Radix Sanguisorbae and/or Moschus, the predominantly removing toxic substances of above pharmacodynamic feature
Removing heat from blood, skin ulcer, the dehumidifying analgesia of dispelling of subsiding a swelling.Radix Sanguisorbae, Moschus play auxiliary to wound hemostasis incrustation, rotten to the corn wound healing as accessory drugss and make
With.After adding this two medicines, the patient serious for hematochezia has good adjuvant treatment effect, quick-acting haemostatic powder, healing wound
Mouthful, general treatment duration can shorten 1-2 days, and cure rate is up to more than 96%.
In order to reach effectively treatment, treating both the principal and secondary aspects of a disease, medicine of the present invention also with Rhizoma Coptidis, Radix Sophorae Flavescentiss, Radix Rubiae, Rhizoma Smilacis Glabrae, Borneolum Syntheticum group
Close.This is because Rhizoma Coptidis are cold in nature, cure mainly removing toxic substances antibacterial, let out clearly blood poison；Radix Sophorae Flavescentiss are cold in nature, cure mainly heat-clearing and toxic substances removing, enteritis dysentery, parasite killing
It is antipruritic；Radix Rubiae is warm in nature, cures mainly cooling blood for hemostasis, dysentery anal fistula；Rhizoma Smilacis Glabrae is mild-natured, cures mainly antibacterial dehumidifying, malignant boil granulation promoting；Borneolum Syntheticum master dissipates
Stagnated fire, the deep heat of energy cure mainly parasite killing, hemorrhoid, energy myogenic pain relieving.Above five kinds of Chinese medicine focuses on hemostasia and promoting granulation, antibacterial, antipruritic solid de-,
Common assistant helps the work(of the monarch and his subjects.Rhizoma Coptidis, Radix Sophorae Flavescentiss, the addition of three accessory drugss of Radix Rubiae mainly improve wound circumference microbial environment, clearly
Thermal detoxification, antibacterial dehumidifying reduce wound infection；It is possible to additionally incorporate Rhizoma Smilacis Glabrae and can promote wound granulation, accelerate wound healing.
Add Borneolum Syntheticum mainly refrigerant sense to be brought in wound, mitigate patient pain's sense, while the effect of Borneolum Syntheticum can also have granulation promoting concurrently promotees
Enter wound healing.Typically can be shortened to 3-5 days according to need the adjustment adjuvant drug, treatment duration of conditions of patients, cure rate can
Up to more than 95%.
Beneficial effect of the present invention：
Raw material of the present invention is simple and easy to get, and Radix Et Rhizoma Rhei and the combination of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) compound recipe make Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) have better healing hemorrhoid
The effect of skin ulcer, with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) as monarch drug, patient uses rear instant effect, of the invention with 3-5 days as a course for the treatment of, through more than 20
The clinical practice in year, treats 1000 many cases of patient altogether, and effective percentage is only treated through one up to 100%, more than 90% patient
Journey can be fully recovered, and control recurrence rate after healing extremely low (only 1 recurs so far, and is spaced more than 10 years with last treatment), the
First use can greatly reduce bleeding, at one's leisure without the sense that comes off, to the intractable hemorrhoid equally spy with rapid healing
Point, a course for the treatment of can be cured.Drug dose prepared by Chinese medicine composition of the present invention is few, but drug effect is powerful, stable curative effect, the state of an illness
Not repeatedly.Radix Sanguisorbae, Moschus, Rhizoma Coptidis, Radix Sophorae Flavescentiss, Radix Rubiae, Rhizoma Smilacis Glabrae and Borneolum Syntheticum can be added according to the state of an illness, compositionss are further enhanced
Detumescence, pain relieving, it is antipruritic, stop blooding, enrich blood, admittedly take off effect.
Specific embodiment
With reference to embodiment, the present invention is further described.
Embodiment 1
Patient：Hu, 40 years old, man suffered from internal hemorrhoid 5 years, once did hemorrhoids operation, and various medicines for treatment are sent out repeatedly
Make, suffer untold misery.On April 10th, 2006, using 35 parts of medicine Radix Et Rhizoma Rhei of the present invention, 15 parts of treatments of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), a painting takes effect,
Medication was fully recovered after 4 days, pays a return visit, does not recur so far.
Embodiment 2
Patient：So-and-so is paid, 28 years old, man suffered from external hemorrhoid 3 years, and various medicines for treatment fail to eradicate.On June 7th, 2016, use
40 parts of medicine Radix Et Rhizoma Rhei of the present invention, 25 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), the treatment of 20 parts of Radix Sanguisorbae, 1 day pain of medication disappear, after medication 3 days
Fully recover, pay a return visit, do not recur so far.
Embodiment 3
Patient：Yao so-and-so, 60 years old, man suffered from internal hemorrhoid 8 years, and hemorrhoid are serious, had blood in stool serious, walk not in terms of.Various use
Medicine is not cured, recurrent exerbation.Calendar year 2001 September 23 days, is controlled using 60 parts of medicine Radix Et Rhizoma Rhei of the present invention, 30 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani)
Treat, after medication 3 days, pain disappears, symptom of conveniently having blood in stool substantially mitigates, and medication was fully recovered after 6 days, did not recurred so far.
Embodiment 4
Patient：Ma, 52 years old, man suffered from internal hemorrhoid 8 years, and hemorrhoid are serious, had blood in stool serious, walk not in terms of.Various use
Medicine is not cured, recurrent exerbation.Calendar year 2001 September 23 days, using 40 parts of medicine Radix Et Rhizoma Rhei of the present invention, 25 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Moschus moschiferouss
After fragrant 8 parts of treatments, medication 3 days, pain disappears, and symptom of conveniently having blood in stool substantially mitigates, and medication was fully recovered after 6 days, not multiple so far
Send out.
Embodiment 5
Patient：Text so-and-so, 59 years old, man, suffer from internal hemorrhoid 3 years, Jing is failed to respond to any medical treatment in many ways, agonizing.On March 23rd, 2011,
The use of 45 parts of medicine Radix Et Rhizoma Rhei of the present invention, 18 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Sanguisorbae is 28 parts, the treatment of 8 parts of Moschus, pain after medication 1 day
Disappear, the state of an illness is clearly better, and medication was fully recovered after 5 days, did not recurred so far.
Embodiment 6
Patient：Jiang so-and-so, 54 years old, female suffered from external hemorrhoid 2 years, and hemorrhoid are more serious.Various medications are not cured.In March, 2011
23 days, using 54 parts of medicine Radix Et Rhizoma Rhei of the present invention, 22 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Sanguisorbae be 24 parts, 18 parts of Radix Rubiae, 38 parts of Rhizoma Smilacis Glabrae, ice
After the treatment of 6 parts of piece, medication 1 day, pain disappears, and the state of an illness is clearly better, and medication was fully recovered after 4 days, did not recurred so far.
Embodiment 7
Patient：Luo, 42 years old, man suffered from internal hemorrhoid 6 years, and hemorrhoid are serious, hematochezia, had a strong impact on work, life.Using this
Did resection operation within 3 years before invention medicine, recurred again afterwards.On August 21st, 2016, using on 37 parts of medicine Radix Et Rhizoma Rhei of the present invention, snow
28 parts of Herba Achilleae, Radix Sanguisorbae are 20 parts, 7 parts of Moschus, 12 parts of Rhizoma Coptidis, the treatment of 25 parts of Radix Sophorae Flavescentiss, after medication 2 days, pain disappears, hematochezia
Symptom substantially mitigates, and medication was fully recovered after 5 days, did not recurred so far.
Embodiment 8
Patient：Song, 69 years old, female suffered from internal hemorrhoid up to 16 years, and hemorrhoid are serious, had blood in stool serious, on foot not aspect.It is various
Medication is not cured, and also once does resection operation, but postoperative recurrence recurrent exerbation soon.On November 13rd, 2004, use
60 parts of medicine Radix Et Rhizoma Rhei of the present invention, 20 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Sanguisorbae be 25 parts, 4 parts of Moschus, 25 parts of Rhizoma Coptidis, 26 parts of Radix Sophorae Flavescentiss, Radix Rubiae 18
After part, 40 parts of Rhizoma Smilacis Glabrae, the treatment of 10 parts of Borneolum Syntheticum, medication 3 days, pain disappears, and symptom of conveniently having blood in stool substantially mitigates, after medication 5 days
Fully recover, do not recur so far.
External medicine composition key agents of the present invention (in terms of parts by weight)：
According to the factor for suffering from each side such as feelings, medication subjective feeling of patient, can be treated using different pharmaceutical formula
Hemorrhoid, to obtaining that shorter treatment time, medication be more comfortable, rapid-onset and other effects, the above does not include all completely
Medication combination and patient's embodiment for being combined using these.
Although reference be made herein to invention has been described for explanatory embodiment of the invention, but above-described embodiment is only this
Invention preferably one of embodiment, embodiments of the present invention are simultaneously not restricted to the described embodiments, it should be appreciated that this area
Technical staff can be designed that a lot of other modifications and embodiment, and these modifications and embodiment will fall in disclosure
Spirit and spirit within.
Claims (10)
1. a kind of external medicine composition for treating hemorrhoid, it is characterised in that its raw material includes the component of following weight proportion：Greatly
Yellow 30-60 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-30 parts.
2. the external medicine composition of hemorrhoid is treated according to claim 1, it is characterised in that：Its raw material includes following weight
The component of proportioning：Radix Et Rhizoma Rhei 40-55 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 10-25 parts.
3. it is according to claim 1 or claim 2 treatment hemorrhoid external medicine composition, it is characterised in that the raw material also includes
Radix Sanguisorbae 20-30 parts.
4. the external medicine composition of hemorrhoid is treated according to claim 1-3 any one, it is characterised in that the raw material
Also include Moschus 1-10 parts.
5. the external medicine composition of hemorrhoid is treated according to claim 1-4 any one, it is characterised in that the raw material
Also include Rhizoma Coptidis 10-30 parts, Radix Sophorae Flavescentiss 20-30 parts, Radix Rubiae 10-30 parts, Rhizoma Smilacis Glabrae 20-50 parts, the one kind in Borneolum Syntheticum 1-15 parts or
The mixture of various ingredients.
6. the external medicine composition of hemorrhoid is treated according to claim 5, it is characterised in that the raw material also includes Rhizoma Coptidis
20-25 parts, Radix Sophorae Flavescentiss 25-30 parts, Radix Rubiae 20-25 parts, Rhizoma Smilacis Glabrae 30-40 parts, one or more component in Borneolum Syntheticum 4-10 parts
Mixture.
7. a kind of external medicine composition for treating hemorrhoid, it is characterised in that its raw material is made up of the component of following weight proportion：
Radix Et Rhizoma Rhei 30-60 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5-30 parts.
8. the external medicine composition according to claim 1-7 any one, it is characterised in that the dosage form of said composition
For unguentum, powder, suppository or lotion.
9. the preparation method of the external medicine composition of hemorrhoid is treated described in claim 1-8 any one, it is characterised in that：It
It is that the medicated powder of the raw material of the proportioning, water extract or/and ethanol extract are mixed, is prepared into external preparation, obtains final product.
10. application of the external medicine composition in medicine for treaching hemorrhoie is prepared as described in any one of claim 1-8.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611064331.7A CN106619854A (en) | 2016-11-28 | 2016-11-28 | External traditional Chinese medicine composition for treating haemorrhoids |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611064331.7A CN106619854A (en) | 2016-11-28 | 2016-11-28 | External traditional Chinese medicine composition for treating haemorrhoids |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110169993A (en) * | 2019-06-28 | 2019-08-27 | 刘克 | Complex composition containing Coelomactra antiquata and its preparation method and application |
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Application publication date: 20170510 |