CN106619843A - Method of preparing natural A/B liquid for relieving depression - Google Patents
Method of preparing natural A/B liquid for relieving depression Download PDFInfo
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- CN106619843A CN106619843A CN201611265249.0A CN201611265249A CN106619843A CN 106619843 A CN106619843 A CN 106619843A CN 201611265249 A CN201611265249 A CN 201611265249A CN 106619843 A CN106619843 A CN 106619843A
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- 239000007788 liquid Substances 0.000 title claims abstract description 101
- 238000000034 method Methods 0.000 title abstract description 8
- 239000000203 mixture Substances 0.000 claims abstract description 30
- 239000003814 drug Substances 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 108090000790 Enzymes Proteins 0.000 claims abstract description 16
- 102000004190 Enzymes Human genes 0.000 claims abstract description 16
- 235000005979 Citrus limon Nutrition 0.000 claims abstract description 14
- 244000131522 Citrus pyriformis Species 0.000 claims abstract description 14
- 238000001125 extrusion Methods 0.000 claims abstract description 14
- 229940076988 freshmint Drugs 0.000 claims abstract description 14
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 9
- 239000008367 deionised water Substances 0.000 claims abstract description 8
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 8
- 239000012153 distilled water Substances 0.000 claims abstract description 8
- 238000010025 steaming Methods 0.000 claims abstract description 3
- 238000002156 mixing Methods 0.000 claims description 17
- 238000013461 design Methods 0.000 claims description 15
- 229940088598 enzyme Drugs 0.000 claims description 15
- 230000002255 enzymatic effect Effects 0.000 claims description 12
- 230000001954 sterilising effect Effects 0.000 claims description 12
- 229940079593 drug Drugs 0.000 claims description 10
- 238000003801 milling Methods 0.000 claims description 9
- 235000003717 Boswellia sacra Nutrition 0.000 claims description 8
- 240000007551 Boswellia serrata Species 0.000 claims description 8
- 235000012035 Boswellia serrata Nutrition 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 8
- 238000000227 grinding Methods 0.000 claims description 8
- 240000008917 Glycyrrhiza uralensis Species 0.000 claims description 7
- 235000000554 Glycyrrhiza uralensis Nutrition 0.000 claims description 7
- 108010059892 Cellulase Proteins 0.000 claims description 6
- 229940106157 cellulase Drugs 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 6
- 238000010411 cooking Methods 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 6
- 239000002002 slurry Substances 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 238000007664 blowing Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 2
- 230000001815 facial effect Effects 0.000 abstract description 5
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 3
- 230000003001 depressive effect Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 239000006228 supernatant Substances 0.000 abstract 2
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- -1 centrifuged Substances 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- 230000007071 enzymatic hydrolysis Effects 0.000 abstract 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 239000013521 mastic Substances 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 239000000935 antidepressant agent Substances 0.000 description 6
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- 230000007774 longterm Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000001430 anti-depressive effect Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
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- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 208000020401 Depressive disease Diseases 0.000 description 2
- 239000004863 Frankincense Substances 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
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- 239000011159 matrix material Substances 0.000 description 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000002194 synthesizing effect Effects 0.000 description 2
- 206010010144 Completed suicide Diseases 0.000 description 1
- 208000034657 Convalescence Diseases 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 229940123445 Tricyclic antidepressant Drugs 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000164 antipsychotic agent Substances 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000009227 behaviour therapy Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008344 brain blood flow Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940125532 enzyme inhibitor Drugs 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000001771 mentha piperita Substances 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000001671 psychotherapy Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 229940076279 serotonin Drugs 0.000 description 1
- 229940126570 serotonin reuptake inhibitor Drugs 0.000 description 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
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Abstract
The invention discloses a method of preparing natural A/B liquid for relieving depression, and belongs to the technical field of medicine. The method comprises the steps that mastic, hanging fruit and similar traditional Chinese medicines are dried in a baking oven, after being ground, the ground substance and distilled water and mixed enzyme are stirred and enzymatic hydrolysis is conducted, the enzymolysis mixture and deionized water are cooked, cooled, ground into thick liquid, centrifuged, and a supernatant is obtained, then the supernatant and the activated clay are mixed and decolorized, and the volume is condensed, after sterilization and disinfection, solution A is obtained, then fresh mint leaves and licorice leaves are mixed to obtain the mixed leaves, then laid flat on a gauze pad, lemon slices are placed on the surfaces, after superheated steaming, the mixtures on the gauze are removed, extrusion liquid is obtained by extruding the remnant, after filtration and disinfection, solution B is obtained, and the natural A/B liquid for relieving depression is obtained. The effective components of the natural A/B liquid for relieving depression can be fully absorbed by the facial part and the neck part, oral administration is not necessary, and the psychological burden of patients with depressive order is alleviated.
Description
Technical field
The invention discloses a kind of preparation method of the natural A/B liquid for alleviating depression, belongs to the technology neck of medicine
Domain.
Background technology
With the continuous development of society, pressure of the people in work, study, life is increasing, so as to more and more
People generate the symptoms such as insomnia, depression, melancholy, neurasthenia, and this symptom has gradually tended to youngization.Depression is
Become an important public health problem in whole health field, the safety and Health of serious harm people.Depression is morbidity
The higher major disease of rate, it is a kind of common disease of psychiatric department, is counted according to the World Health Organization, and depression has become the world
4th big illness.Depressive patients are the people at highest risk for committing suiside, and are fallen ill to convalescence in patient, there is the danger of suicide all the time.Suppression
The identifying and diagnosing rate of strongly fragrant disease is very low, and only about 1/5～1/4 patient is correctly diagnosed.Effective cure rate of depression
Also very low, only about 1/4～1/3 patient obtains effective anti depressant therapy.Based on above reason, current antidepressant
Possess extensive market prospects.
But there is many defects in current depression medicine.The treatment method of depression can be divided into medicine and control
Treatment, psychotherapy, sociotherapy and behaviour therapy.Depression that is occurred frequently and being difficult to effect a radical cure gradually is constructing considerable antidepression
Medicine market, this one of the main reasons that exactly research and development of recent domestic Central nervous systemic drug are especially enlivened.Institute
It is divided to synthetic drug and the big class of natural drug two again with medicine.At present conventional synthesis class antidepressants species has monoamine to aoxidize
Enzyme inhibitor, tricyclic antidepressant, heterocyclic antidepressants, serotonin and NRI, go
Methylepinephrine and specific serotonin reuptake inhibitor.More than in addition to several big class, also much with certain antidepression work
Medicine is used for clinic, the medicine of various central neurotransmitter conduction functions is such as adjusted, while some antipsychotic drugs
There is antidepressant effect, auxiliary treatment can be made, the antidepression spectrum for synthesizing the most presence of antidepressants is narrow, but large side effects, medicine valency are high
With easily recurrence；Because the treatment of depression is a long-term process, long-term taking causes the toxic and side effect of medicine to increase.
The content of the invention
The technical problem to be solved：Antidepression spectrum for synthesizing the most presence of antidepressants is narrow, but pair is made
High with big, medicine valency, while the treatment of depression is a long-term process, long-term taking causes what the toxic and side effect of medicine increased
Defect, there is provided a kind of utilization frankincense, hang the pharmacology of fruit, Radix Angelicae Sinensis and red medicine, as brain blood circulation is promoted, increases
Brain oxygen supply, improves the matrix of the state of mind, and it is carried out to digest boiling extraction, working substance is obtained, as A liquid, then with peppermint
Leaf and Leaves of Glycyrrhiza Uralensis Fisch suppress the matrix of brain induction disease as refreshing the mind, and it is extracted, and obtain B liquid, are used for so as to be obtained
Alleviate depression natural A/B liquid, the present invention by frankincense, hang fruit etc. Chinese medicine be dried in an oven, after grinding will grinding
Thing is stirred enzymolysis with distilled water and mixed enzyme, secondly enzymolysis mixture and deionized water is carried out into boiling, cools down, defibrination,
Centrifugation, obtains upper liquid, then upper liquid is mixed into decolouring and concentration volume with atlapulgite, and sterilizing obtains A liquid, then will be new
Fresh mint leaf mixes with Leaves of Glycyrrhiza Uralensis Fisch must mix leaf, and be divided on pad of cotion, and lemon tablet is placed in into surface, and superheated steam blows
The mixture on gauze is removed afterwards, extrusion liquid is extruded residue to obtain, and is filtered and obtain after sterilization B liquid, you can must alleviate depression
Natural A/B liquid.The active ingredient of the natural A of the alleviation depression obtained by the present invention/B liquid fully can be absorbed by face and neck,
Without the need for oral, the burden at heart of patients with depression is reduced.
To solve above-mentioned technical problem, the present invention is using technical scheme as described below：
（1）Count by weight, take 40～50 parts of frankincenses, 30～35 parts hang fruit, 10～15 parts of Radix Angelicae Sinensis and 6～8 parts of red medicines, put
In entering baking oven, design temperature is 45～50 DEG C, is dried 5～6h, then dried object is put into grinding mill is ground with 200r/min
Mill, collects thing of milling, thing, distilled water and the mixed enzyme of milling in mass ratio 12:20:1～12:20:3 are put into enzymatic vessel, if
Constant temperature degree is 34～36 DEG C, with 120r/min stirring 5～7h of enzymolysis；The mixed enzyme be cellulase and pectase in mass ratio
2:1 mixes；
（2）After above-mentioned enzymolysis terminates, the enzymolysis mixture in enzymatic vessel is put into cooker, then enzyme is added in cooker
The deionized water of 2～3 times of mixture quality of solution, design temperature is 95～105 DEG C, and 9～12h of boiling naturally cools to room temperature, will
Cooking mixture is put into defibrination in fiberizer, collects slurries, and is put into centrifuge, and 10～15min is centrifuged with 1200r/min,
Collect upper liquid,
（3）Above-mentioned upper liquid is mixed into 10～15min of decolouring with the atlapulgite of above-mentioned upper liquid quality 10～15%, was carried out
Filter, collects destainer, and destainer is put into vacuum concentration pot, is concentrated into the 60～70% of original volume, collects concentrate and kills
Bacterium is sterilized, and obtains A liquid, standby；
（4）In mass ratio 1:1, take fresh mint leaf and fresh Leaves of Glycyrrhiza Uralensis Fisch is well mixed, mixing leaf is obtained, then uniformly divide in aqueous
Measure on the hospital gauze pad for 10～15%, hospital gauze mat thickness is 6～9cm, and hospital gauze pad is placed in container, is taken
The thickness of the quality such as fresh mint leaf is that the lemon tablet of 0.6～0.9cm is homogeneously disposed in mixing leaf surface, using 280 DEG C of overheated steamings
Vapour blows downwards 30～50min with 10L/min from 10～15cm directly over lemon tablet；
（5）After above-mentioned superheated steam blowing beam, the mixture on pad of cotion is removed, the residue in container is put into forcing press
In, extruded with 20MPa, extrusion liquid is collected, 5～7h is stood at extrusion liquid is placed in into 4 DEG C, filtered, collect filtered fluid
And sterilizing, B liquid is obtained, by step（3）Standby A liquid and B liquid presses equal-volume, respectively loaded on two aseptic bottles in, you can
For alleviating the natural A/B liquid of depression.
The present invention application process be：The natural A of the alleviation depression obtained by the present invention/B liquid needs respectively to use once sooner or later,
Daytime is first cleaned up face and neck using front, pours 10～15mLB liquid into the centre of the palm, is uniformly applied to face and neck
Portion, and soft 3～5min, then by 10～15mLA liquid are uniformly applied to face and neck again, and soft 3～5min, evening makes
Equally first face and neck cleaned up with front, 10～15mLA liquid is uniformly applied into face and neck, soft 5～
7min, after testing, after the natural A for alleviating depression/B liquid 2～3 weeks of the patient using present invention preparation, depression
Disease sends out rate and reduces by 70～80%, and harmless, and patient facial region is ruddy, energetic.
Compared with additive method, Advantageous Effects are the present invention：
（1）The natural A for alleviating depression/B liquid manufacture craft obtained by the present invention is simple, easy to use, and active ingredient
Can be fully absorbed by face and neck；
（2）The natural A for alleviating depression/B liquid obtained by the present invention has no toxic side effect to the patient for treating depression, can push away
Extensively use.
Specific embodiment
Count by weight, take 40～50 parts of frankincenses, 30～35 parts hang fruit, 10～15 parts of Radix Angelicae Sinensis and 6～8 parts of red medicines,
In being put into baking oven, design temperature is 45～50 DEG C, is dried 5～6h, then dried object is put into grinding mill is carried out with 200r/min
Mill, collect thing of milling, thing, distilled water and the mixed enzyme of milling in mass ratio 12:20:1～12:20:3 are put into enzymatic vessel,
Design temperature is 34～36 DEG C, with 120r/min stirring 5～7h of enzymolysis；The mixed enzyme is that cellulase and pectase press quality
Than 2:1 mixes；After above-mentioned enzymolysis terminates, the enzymolysis mixture in enzymatic vessel is put into cooker, then to cooker
Middle to add the deionized water for digesting 2～3 times of mixture quality, design temperature is 95～105 DEG C, 9～12h of boiling, natural cooling
To room temperature, cooking mixture is put into defibrination in fiberizer, collects slurries, and be put into centrifuge, with 1200r/min 10 are centrifuged
～15min, collect upper liquid, by above-mentioned upper liquid mix with the atlapulgite of above-mentioned upper liquid quality 10～15% decolourize 10～
15min, is filtered, and collects destainer, and destainer is put into vacuum concentration pot, is concentrated into the 60～70% of original volume, is received
Collection concentrate and sterilizing, obtain A liquid, standby；In mass ratio 1:1, take fresh mint leaf and fresh Leaves of Glycyrrhiza Uralensis Fisch is well mixed, obtain
Mixing leaf, then uniformly divide on the hospital gauze pad that water content is 10～15%, hospital gauze mat thickness is 6～9cm, and will
Hospital gauze pad is placed in container, and the thickness for taking the quality such as fresh mint leaf is that the lemon tablet of 0.6～0.9cm is homogeneously disposed in mixing
Leaf surface, 30～50min is blown downwards using 280 DEG C of superheated steams with 10L/min from 10～15cm directly over lemon tablet；Upper
After stating superheated steam blowing beam, the mixture on pad of cotion is removed, the residue in container is put into forcing press, with 20MPa
Extruded, collected extrusion liquid, 5～7h is stood at extrusion liquid is placed in into 4 DEG C, filtered, collected filtered fluid and sterilizing,
B liquid, standby A liquid and B liquid are pressed into equal-volume, respectively loaded on two aseptic bottles in, you can must be used to alleviate the day of depression
Right A/B liquid.
Example 1
Count by weight, take 40 parts of frankincenses, 30 parts hang fruit, 10 parts of Radix Angelicae Sinensis and 6 parts of red medicines, in being put into baking oven, design temperature
For 45 DEG C, 5h is dried, then dried object is put into grinding mill is milled with 200r/min, collection is milled thing, thing of milling, steamed
Distilled water and mixed enzyme in mass ratio 12:20:1 is put into enzymatic vessel, and design temperature is 34 DEG C, with 120r/min stirring enzymolysis 5h；
The mixed enzyme is cellulase and pectase in mass ratio 2:1 mixes；After above-mentioned enzymolysis terminates, by enzymatic vessel
Enzymolysis mixture is put into cooker, then addition digests the deionized water of 2 times of mixture quality in cooker, and design temperature is
95 DEG C, boiling 9h naturally cools to room temperature, and cooking mixture is put into defibrination in fiberizer, collects slurries, and is put into centrifuge
In, 10min is centrifuged with 1200r/min, upper liquid is collected, by the atlapulgite of above-mentioned upper liquid and above-mentioned upper liquid quality 10%
Mixing decolouring 10min, is filtered, and collects destainer, and destainer is put into vacuum concentration pot, is concentrated into original volume
60%, concentrate and sterilizing are collected, A liquid is obtained, it is standby；In mass ratio 1:1, take fresh mint leaf and the mixing of fresh Leaves of Glycyrrhiza Uralensis Fisch
Uniformly, mixing leaf is obtained, then is uniformly divided on the hospital gauze pad that water content is 10%, hospital gauze mat thickness is 6cm, and will
Hospital gauze pad is placed in container, and the thickness for taking the quality such as fresh mint leaf is homogeneously disposed in mixing leaf table for the lemon tablet of 0.6cm
Face, 30min is blown downwards using 280 DEG C of superheated steams with 10L/min from 10cm directly over lemon tablet；Blow in above-mentioned superheated steam
After end, the mixture on pad of cotion is removed, the residue in container is put into forcing press, extruded with 20MPa, collected
Extrusion liquid, at extrusion liquid is placed in into 4 DEG C 5h is stood, and is filtered, and collects filtered fluid and sterilizing, B liquid is obtained, by standby A
Liquid and B liquid press equal-volume, respectively loaded on two aseptic bottles in, you can must be used to alleviate the natural A/B liquid of depression.
The natural A of the alleviation depression obtained by the present invention/B liquid is needed sooner or later respectively using once, and daytime uses front first by face
Clean up with neck, pour 10mLB liquid into the centre of the palm, be uniformly applied to face and neck, and soft 3min, then inciting somebody to action
10mLA liquid is uniformly applied to face and neck, soft 3min, and equally first cleaned up face and neck using front in the evening,
10mLA liquid is uniformly applied into face and neck, soft 5min, after testing, patient uses prepared by the present invention to be used for
After alleviating the natural A/B liquid 2 weeks of depression, depression disease sends out rate and reduces by 70%, and harmless, and patient facial region is ruddy, essence
God is full.
Example 2
Count by weight, take 50 parts of frankincenses, 35 parts hang fruit, 15 parts of Radix Angelicae Sinensis and 8 parts of red medicines, in being put into baking oven, design temperature
For 50 DEG C, 6h is dried, then dried object is put into grinding mill is milled with 200r/min, collection is milled thing, thing of milling, steamed
Distilled water and mixed enzyme in mass ratio 12:20:3 are put into enzymatic vessel, and design temperature is 36 DEG C, with 120r/min stirring enzymolysis 7h；
The mixed enzyme is cellulase and pectase in mass ratio 2:1 mixes；After above-mentioned enzymolysis terminates, by enzymatic vessel
Enzymolysis mixture is put into cooker, then addition digests the deionized water of 3 times of mixture quality in cooker, and design temperature is
105 DEG C, boiling 12h naturally cools to room temperature, and cooking mixture is put into defibrination in fiberizer, collects slurries, and is put into centrifugation
In machine, 15min is centrifuged with 1200r/min, collects upper liquid, above-mentioned upper liquid is white with the activity of above-mentioned upper liquid quality 15%
Soil mixing decolouring 15min, is filtered, and collects destainer, and destainer is put into vacuum concentration pot, is concentrated into original volume
70%, concentrate and sterilizing are collected, A liquid is obtained, it is standby；In mass ratio 1:1, take fresh mint leaf and the mixing of fresh Leaves of Glycyrrhiza Uralensis Fisch
Uniformly, mixing leaf is obtained, then is uniformly divided on the hospital gauze pad that water content is 15%, hospital gauze mat thickness is 9cm, and will
Hospital gauze pad is placed in container, and the thickness for taking the quality such as fresh mint leaf is homogeneously disposed in mixing leaf table for the lemon tablet of 0.9cm
Face, 50min is blown downwards using 280 DEG C of superheated steams with 10L/min from 15cm directly over lemon tablet；Blow in above-mentioned superheated steam
After end, the mixture on pad of cotion is removed, the residue in container is put into forcing press, extruded with 20MPa, collected
Extrusion liquid, at extrusion liquid is placed in into 4 DEG C 7h is stood, and is filtered, and collects filtered fluid and sterilizing, B liquid is obtained, by standby A
Liquid and B liquid press equal-volume, respectively loaded on two aseptic bottles in, you can must be used to alleviate the natural A/B liquid of depression.
The natural A of the alleviation depression obtained by the present invention/B liquid is needed sooner or later respectively using once, and daytime uses front first by face
Clean up with neck, pour 15mLB liquid into the centre of the palm, be uniformly applied to face and neck, and soft 5min, then inciting somebody to action
15mLA liquid is uniformly applied to face and neck, soft 5min, and equally first cleaned up face and neck using front in the evening,
15mLA liquid is uniformly applied into face and neck, soft 7min, after testing, patient uses prepared by the present invention to be used for
After alleviating the natural A/B liquid 3 weeks of depression, depression disease sends out rate and reduces by 80%, and harmless, and patient facial region is ruddy, essence
God is full.
Example 3
Count by weight, take 45 parts of frankincenses, 33 parts hang fruit, 12 parts of Radix Angelicae Sinensis and 7 parts of red medicines, in being put into baking oven, design temperature
For 47 DEG C, 5.5h is dried, then dried object is put into grinding mill is milled with 200r/min, collection is milled thing, thing of milling,
Distilled water and mixed enzyme in mass ratio 12:20:2 are put into enzymatic vessel, and design temperature is 35 DEG C, are digested with 120r/min stirrings
6h；The mixed enzyme is cellulase and pectase in mass ratio 2:1 mixes；After above-mentioned enzymolysis terminates, by enzymatic vessel
In enzymolysis mixture be put into cooker, then in cooker add enzymolysis 2 times of mixture quality deionized water, setting temperature
Spend for 100 DEG C, boiling 10.5h naturally cools to room temperature, cooking mixture is put into defibrination in fiberizer, collect slurries, and put
In entering centrifuge, 103min is centrifuged with 1200r/min, upper liquid is collected, by above-mentioned upper liquid and above-mentioned upper liquid quality 12%
Atlapulgite mixing decolouring 13min, filtered, collect destainer, destainer is put into vacuum concentration pot, be concentrated into original
The 65% of volume, collects concentrate and sterilizing, obtains A liquid, standby；In mass ratio 1:1, take fresh mint leaf and fresh Radix Glycyrrhizae
Leaf is well mixed, and obtains mixing leaf, then uniformly divides on the hospital gauze pad that water content is 12%, and hospital gauze mat thickness is
7cm, and hospital gauze pad is placed in container, the thickness for taking the quality such as fresh mint leaf is homogeneously disposed in for the lemon tablet of 0.8cm
Mixing leaf surface, 40min is blown downwards using 280 DEG C of superheated steams with 10L/min from 13cm directly over lemon tablet；In above-mentioned mistake
After vapours blowing beam, the mixture on pad of cotion is removed, the residue in container is put into forcing press, carried out with 20MPa
Extruding, collects extrusion liquid, and at extrusion liquid is placed in into 4 DEG C 6h is stood, and is filtered, and collects filtered fluid and sterilizing, obtains B liquid,
Standby A liquid and B liquid are pressed into equal-volume, respectively loaded on two aseptic bottles in, you can must be used to alleviate the natural A/B of depression
Liquid.
The natural A of the alleviation depression obtained by the present invention/B liquid is needed sooner or later respectively using once, and daytime uses front first by face
Clean up with neck, pour 12mLB liquid into the centre of the palm, be uniformly applied to face and neck, and soft 4min, then inciting somebody to action
12mLA liquid is uniformly applied to face and neck, soft 4min, and equally first cleaned up face and neck using front in the evening,
12mLA liquid is uniformly applied into face and neck, soft 6min, after testing, patient uses prepared by the present invention to be used for
After alleviating the natural A/B liquid 3 weeks of depression, depression disease sends out rate and reduces by 75%, and harmless, and patient facial region is ruddy, essence
God is full.
Claims (1)
1. a kind of preparation method of the natural A/B liquid for alleviating depression, it is characterised in that be specifically prepared as：
（1）Count by weight, take 40～50 parts of frankincenses, 30～35 parts hang fruit, 10～15 parts of Radix Angelicae Sinensis and 6～8 parts of red medicines, put
In entering baking oven, design temperature is 45～50 DEG C, is dried 5～6h, then dried object is put into grinding mill is ground with 200r/min
Mill, collects thing of milling, thing, distilled water and the mixed enzyme of milling in mass ratio 12:20:1～12:20:3 are put into enzymatic vessel, if
Constant temperature degree is 34～36 DEG C, with 120r/min stirring 5～7h of enzymolysis；The mixed enzyme be cellulase and pectase in mass ratio
2:1 mixes；
（2）After above-mentioned enzymolysis terminates, the enzymolysis mixture in enzymatic vessel is put into cooker, then enzyme is added in cooker
The deionized water of 2～3 times of mixture quality of solution, design temperature is 95～105 DEG C, and 9～12h of boiling naturally cools to room temperature, will
Cooking mixture is put into defibrination in fiberizer, collects slurries, and is put into centrifuge, and 10～15min is centrifuged with 1200r/min,
Collect upper liquid,
（3）Above-mentioned upper liquid is mixed into 10～15min of decolouring with the atlapulgite of above-mentioned upper liquid quality 10～15%, was carried out
Filter, collects destainer, and destainer is put into vacuum concentration pot, is concentrated into the 60～70% of original volume, collects concentrate and kills
Bacterium is sterilized, and obtains A liquid, standby；
（4）In mass ratio 1:1, take fresh mint leaf and fresh Leaves of Glycyrrhiza Uralensis Fisch is well mixed, mixing leaf is obtained, then uniformly divide in aqueous
Measure on the hospital gauze pad for 10～15%, hospital gauze mat thickness is 6～9cm, and hospital gauze pad is placed in container, is taken
The thickness of the quality such as fresh mint leaf is that the lemon tablet of 0.6～0.9cm is homogeneously disposed in mixing leaf surface, using 280 DEG C of overheated steamings
Vapour blows downwards 30～50min with 10L/min from 10～15cm directly over lemon tablet；
（5）After above-mentioned superheated steam blowing beam, the mixture on pad of cotion is removed, the residue in container is put into forcing press
In, extruded with 20MPa, extrusion liquid is collected, 5～7h is stood at extrusion liquid is placed in into 4 DEG C, filtered, collect filtered fluid
And sterilizing, B liquid is obtained, by step（3）Standby A liquid and B liquid presses equal-volume, respectively loaded on two aseptic bottles in, you can
For alleviating the natural A/B liquid of depression.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109393613A (en) * | 2018-10-22 | 2019-03-01 | 安徽罗曼丝发制品有限公司 | A kind of means of defence extending wig service life |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042880A (en) * | 2014-07-10 | 2014-09-17 | 崇州市地龙海龙生物制品开发研究所 | Method for preparing preparation for treating insomnia |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104042880A (en) * | 2014-07-10 | 2014-09-17 | 崇州市地龙海龙生物制品开发研究所 | Method for preparing preparation for treating insomnia |
Cited By (1)
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| CN109393613A (en) * | 2018-10-22 | 2019-03-01 | 安徽罗曼丝发制品有限公司 | A kind of means of defence extending wig service life |
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