CN106619122A - Fully-closed sterile intelligent integrated pharmaceutical system - Google Patents

Fully-closed sterile intelligent integrated pharmaceutical system Download PDF

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Publication number
CN106619122A
CN106619122A CN201611012424.5A CN201611012424A CN106619122A CN 106619122 A CN106619122 A CN 106619122A CN 201611012424 A CN201611012424 A CN 201611012424A CN 106619122 A CN106619122 A CN 106619122A
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CN
China
Prior art keywords
separator
centrifugal cyclone
cyclone separator
fully
cyclone separators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611012424.5A
Other languages
Chinese (zh)
Inventor
刘振峰
杨春艳
赖小锋
易小禄
赖勇
黄建祥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yichun Wanshen Pharmaceutical Machinery Co Ltd
Original Assignee
Yichun Wanshen Pharmaceutical Machinery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Yichun Wanshen Pharmaceutical Machinery Co Ltd filed Critical Yichun Wanshen Pharmaceutical Machinery Co Ltd
Priority to CN201611012424.5A priority Critical patent/CN106619122A/en
Publication of CN106619122A publication Critical patent/CN106619122A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/40Heating or cooling means; Combinations thereof
    • A61J2200/42Heating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/21Pharmaceuticals, e.g. medicaments, artificial body parts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Cyclones (AREA)

Abstract

The invention discloses a fully-closed sterile intelligent integrated pharmaceutical system. The fully-closed sterile intelligent integrated pharmaceutical system comprises a raw material charging device, a gas generator, a sterilization separation device and a cleaning device. The sterilization separation device comprises a primary separator, a secondary separator and corresponding steam recoverers of the primary separator and the secondary separator. The separators are centrifugal cyclone separators. The system is characterized in that flow guiding separation spiral annular plates are arranged on the peripheral walls of the centrifugal cyclone separators in the axis direction of the centrifugal cyclone separators in a surrounding mode, and axial direction lines of inlets and outlets formed in the lower portions and the upper portions of the centrifugal cyclone separators respectively are tangent to rotating curves of the flow guiding separation spiral annular plates. Dust-free and sterile conveying of materials can be truly achieved, conveying efficiency is high, safety and reliability are achieved, primary and secondary pollution can be effectively avoided, the large-scale production degree of enterprises can be increased, and the quality and production efficiency of products can be improved.

Description

Full closed aseptic intelligent integral pharmacy system
Technical field
The present invention relates to a kind of pharmaceutical equipment technical field, more particularly to a kind of full closed aseptic intelligent integral pharmacy system System.
Background technology
The existing equipment for used by raw material medicinal powder, the sterilizing-drying of chemical powder, is batch (-type) multiple operation mixing system The independent production equipment made, needs to arrange a turnover equipment between each operation or is manually had enough to meet the need, and container and powder are multiple It is exposed so easily to make sterilizing complete to be dried the raw material exposure after cooling in atmosphere in the work environment, generate secondary Pollution, and so production efficiency is low, and labor strength is big, while large-scale production is limited to a certain extent, it is special Be not that amount of bacteria is exceeded, it is easy to produce secondary pollution and infection, seriously perplexed modern enterprise powder material production it is suitable Profit is carried out, so that seriously constraining the development of the scale intensive manufacture of enterprise.
The content of the invention
The purpose of the present invention is the problem existed for prior art, there is provided a kind of full closed aseptic intelligent integral pharmacy System.This full closed aseptic intelligent integral pharmacy system can be truly realized the dustless of material, asepticization conveying, transfer efficiency It is high, safe and reliable, can be prevented effectively from once and secondary pollution, enterprise scale production degree is improved, improve the quality of product And production efficiency.
Full closed aseptic intelligent integral pharmacy system of the present invention includes device for charging material, gas generator, sterilizing point From device, cleaning device, the sterilizing separator includes a separator and second separator and its corresponding Steam Recovery Device, the separator is a centrifugal cyclone separator, be it is characterized in that on described its perisporium of centrifugal cyclone separator along its axis side Spiral ring flat-plate is separated to water conservancy diversion is arranged with, the axle of the bottom of centrifugal cyclone separator and the entrance and exit on top is opened in respectively It is tangent with the rotating curve that the water conservancy diversion separates spiral ring flat-plate respectively to direction line.
The water conservancy diversion of the centrifugal cyclone separator separate spiral ring flat-plate its from external diameter side toward internal diameter side downward or upward Incline oblique.
The full closed aseptic intelligent integral pharmacy system of the present invention its each device such as control device, raw material for constituting system Charging apparatus, gas generator, sterilizing separator etc. adopt modularized design, can be had according to the different demands of client Targetedly multimode combination, plays the different technologies advantage of each submodule block system, is that client makes optimization system to measure Production decision, and itself automaticity of each submodule block system is higher, with production efficiency it is high, labour intensity is low, operation control The features such as system is intelligent.Its oil-free air pump, air heater can provide health, oil-free, aseptic, pressure for line production system The adjustable clean air source of temperature.
Its control device can automatic detection, adjustment, control cleaning agent process units is cleaned, meet it is extensive, The efficiency of long-time production.The design of cleaning device improves the security of product with application, saves the operating time, improves Efficiency, saving labour, guarantee safe operation, save water, steam equal energy source, and production equipment is capable of achieving maximization, Automated water Flat height.
Description of the drawings
Fig. 1 is one embodiment of the invention structural representation.Fig. 2 is that the example structure of air heater one in Fig. 1 is illustrated Figure.Fig. 3 is the example structure schematic diagram of cyclone separator one in Fig. 1.Figure 4 and 5 are respectively the cyclone separator in invention The structural representation of embodiment 2 and 3.Fig. 6 is the example structure schematic diagram of steam generator one in the present invention.
Specific embodiment
To have a better understanding of the present invention, accompanying drawing is combined by the following examples the principle and feature of the present invention are entered Row description, as shown in Figure 1-2, the system, control device, device for charging material, gas generator, sterilizing separator, cleaning Device etc., its control device includes manual overvide and intellectual automaton, and manual overvide includes corresponding Operation control platform, operational control cabinet.
Its device for charging material is arranged at described manual overvide side, and device for charging material includes raw material memory 10th, material lifting conveyer 11, control cabinet, feed hopper 13, described raw material memory 10, its port of export by pipeline with it is described Material lifting conveyer 11 inlet end connection, described material lifting conveyer 11, its exit end by pipeline with The inlet end connection of described feed hopper 13.Raw material memory 10 is connected with a material-pulverizing device 4.Material-pulverizing device A device for transporting objects can be connected between raw material memory 10.
The top of feed hopper 13 is provided with Butterworth Hatch, and its side is provided with stuff level switch, gas generator, and it is arranged at The bottom of the operation control platform of manual overvide, gas generator, including air pump 5, air heater 6, special-shaped t-bend 7a, steam generator 8, special-shaped t-bend 7a, its one end is provided with an import, another import, and the other end arranges outlet, described sky Its exit end of air pump 5 is connected by pipeline and corresponding control valve with the import of described air heater 6, described sky Air pump 5, it is specially oil-free air pump, described air heater 6, its exit end by corresponding threeway, pipeline and/or And corresponding control valve is connected with an import of special-shaped t-bend 7a;Described steam generator 8, its inlet end by pipeline, Corresponding to control the external steaming of valve, the exit end of steam generator 8 is by pipeline, corresponding control valve and special-shaped t-bend 7a Another import connection.
The air heater 6 includes that heating chamber 61, combustion chamber 62, combustion exhaust 63, combustion air intake 64, air enter Gas port 65, air exhaust port 66, fuel from combustion air intake into combustion chamber in burnt, the waste gas produced during burning is from combustion Burn exhaust outlet to discharge;Cold air enters temperature after the heat that combustion chamber is absorbed in heating chamber from air inlet and raises, then from sky Gas exhaust outlet is exported.
Sterilizing separator is arranged at manual overvide one end, and sterilizing separator includes rotary valve 14, special-shaped t-bend 7b, separator 18, separator 18 is a cyclone separator, and cyclone separator includes cyclone separator 18a, a secondary cyclone point It is described from device 18b, primary steam recover 22a, indirect steam recover 22b, filter 23a, an aflter-fillter 23b Mixing duct 15, its one end is connected with the port of export of rotary valve 14, the other end and a cyclone separator 18a inlet end Connection, described its upper outlet of cyclone separator 18a is by pipeline, corresponding control valve and primary steam recover 22a It is connected, described its top of primary steam recover 22a is provided with a filter 23a, and special-shaped t-bend 7b its one ends set Two imports and an outlet are equipped with, air duct 16 is by an import of special-shaped t-bend 7b, outlet and a cyclone separator 18a The threeway of lower outlet, corresponding control valve be connected with the inlet end of secondary cyclone separator 18b, secondary cyclone separator The upper outlet of 18b is connected by corresponding pipeline, control valve and indirect steam recover 22b.
Cyclone separator 18a and secondary cyclone separator 18b be cyclone separator, described indirect steam recover Its top of 22b is provided with aflter-fillter 23b.
It is arranged at the side of sterilizing separator to described cleaning device, and described cleaning device includes that support, heat are handed over Parallel operation 20, reflux pump 26, feed pump 29, pure water pot 1, acid solution tank 2, alkali liquid tank 3, peep hole, blow-down pipe, pressure gauge etc..Heat Exchanger 20, reflux pump 26 and feed pump 29 are arranged on corresponding support.Described heat exchanger 20 is heat-exchangers of the plate type.
Its cleaning flow container includes that the port of export of pure water pot 1, acid solution tank 2 and the/bottom of alkali liquid tank 3 passes through respectively corresponding three The inlet end connection of logical, control valve, pipeline and heat exchanger 20, its exit end of heat exchanger 20 is by pipeline and feed pump 29 inlet end connection.
The exit end of described feed pump 29 is by flexible pipe and the Butterworth Hatch on the top of feed hopper 13 of device for charging material Connection.The refluxing opening one end at the top of pure water pot 1, acid solution tank 2 and alkali liquid tank 3 is by threeway, corresponding control valve and pipe Road is connected with the port of export of reflux pump 26.
The arrival end of described reflux pump 26 is another with the special-shaped t-bend 7b of described sterilizing separator by flexible pipe Import connects, and described pure water pot 1, acid solution tank 2, the top of alkali liquid tank 3 are respectively arranged with peep hole, blow-down pipe, pressure gauge, The port of export of the feed hopper 13 of described device for charging material connects with the entrance point of the rotary valve 14 of described sterilizing separator Connect, described its one end of air duct 16 of sterilizing separator is heated by corresponding control valve with the air of gas generator The threeway connection of the exit end of device 6, one end of mixing duct 15 of described sterilizing separator and the abnormity of gas generator The outlet connection of threeway 7a.
During operation, powder material is put into raw material memory 10, transported material to by material lifting conveyer 11 Feed hopper 13, opens rotary valve 14, and powder material enters mixing duct, starts gas generator, and air pump 5 sends into air Air heater 6, what the steam and the Jing air heaters 6 of air pump 5 that special-shaped t-bend 7a produces steam generator 8 was heated Corresponding mixing duct is imported after air mixing, steam carries out high-temperature sterilization to powder material, while powder material is blown into one Secondary cyclone separator 18a, a cyclone separator 18a starts to be separated high-temperature steam and powder material, and high-temperature steam leads to The top duct of separator 18 is crossed into corresponding primary steam recover 22a, primary steam recover 18a carries out high-temperature steam Reclaim, filter, powder material is entered by the threeway of separator 18a bottoms and is sent to air heater 6, Jing by air pump 5 again The air of the heating of air heater 6 will be sent into secondary cyclone separator 18b, secondary cyclone through the powder material of first separation Powder material is carried out secondary separation by separator 18b, and the steam isolated enters indirect steam recover by corresponding pipeline 22b is reclaimed, filtered.
In the embodiment of the present invention 2, its cyclone separator is as shown in figure 3, including separator body 31, separator body 31 Inside there is the cyclonic separation chamber 32 that can make that the air-flow of dust-laden internally rotates, be provided with separator body 31 For the air-flow of dust-laden is introduced to cyclonic separation chamber entrance 33, after dust is by cyclonic separation by air-flow from described The exhaust outlet 35 discharged of cyclonic separation chamber and after dust is by cyclonic separation dust is discharged from cyclonic separation chamber 32 Ash port 34, entrance 33, exhaust outlet 35, ash port 34 are connected with the inside of cyclonic separation chamber 32.In the embodiment, rotation Wind disengagement chamber 32 includes top cyclonic separation chamber 36 and bottom cyclonic separation chamber 37, top cyclonic separation chamber 36 in internal diameter extremely The truncated cone-shaped tapered under above, both join for top cyclonic separation chamber 36 and bottom cyclonic separation chamber 37, and the two Cavity wall smoothly transits at the place of connecting.Exhaust outlet 35 is located at the upper end of top cyclonic separation chamber 36, and ash port 34 is located at down The bottom of portion's cyclonic separation chamber 37, air-flow rotates around first axle 38 in top cyclonic separation chamber 36, revolves in bottom Rotate around second axis 39 in wind disengagement chamber 37, first axle 37 is a straight line, second axis 39 and first axle 39 It is in the same plane and both intersect at a point.In the embodiment, second axis can be line or broken line or curve always, And first axle 38 is in the angle a more than 90 less than 180 ° in intersection with the tangent line of second axis 39 or second axis 39, In embodiment, second axis 39 are 115 ° for the angle a of a straight line, first axle 38 and second axis 39, second axis 39 Through the plane that the end face of ash port 24 is located, and the plane that second axis 39 are located with the end face of ash port 24 is in intersection Angle b be 85 °.
In the embodiment of the present invention 3, its separator is a circle as shown in figure 4, the separator is a centrifugal cyclone separator 41 It is arranged with water conservancy diversion on cylindricality, centrifugal cyclone separator 41 its housing internal perisporium from bottom to top and separates spiral ring flat-plate 42, opens up respectively Spiral is separated in the entrance 44 on the bottom of centrifugal cyclone separator 41 and top and the axial direction line of outlet 45 with water conservancy diversion respectively The rotating curve of ring flat-plate 42 is tangent so that the boiler smoke into centrifugal cyclone separator 41 is made from bottom to top in its inner chamber formation The flue dust of centrifugal rotational flow is separated so as to which smokeshade separates spiral shell from the hollow bulb and/or water conservancy diversion of centrifugal cyclone separator Rotation ring flat-plate is fallen into the collecting chamber 43 of its underpart.
In the embodiment of the present invention 4, its separator is as shown in figure 5, centrifugal cyclone separator 41 is in a truncated cone-shaped, its water conservancy diversion point Reduced diameter from bottom to top is from spiral ring flat-plate 42 and its housing.Remaining structure can be similar with above-described embodiment.Centrifugation The water conservancy diversion of cyclone separator separates spiral ring flat-plate from its external diameter(It is connected with its housing internal perisporium)Side is toward internal diameter(By its center Line)Side is downward or upper oblique, further to improve separating effect.
In the embodiment of the present invention 5, as shown in fig. 6, the steam generator of its gas generator includes housing, set in housing The calandria 51 put, steam flow channel, the two ends of steam flow channel are respectively water inlet 54 and go out to steam mouth 52.As shown in Fig. 3, Fig. 4, Steam flow channel is set to spirality stainless steel metal pipe(Spiral metal coil pipe), heating tube 53 is set to spirality(Spirally Metal coil pipe), heating tube coated by stainless steel metal pipe, and the direction of spiraling of heating tube and stainless steel metal pipe is mutually perpendicular to, plus Heat pipe is by metal tube clad.Metal tube is set to stainless steel tube.Steam generator can install temperature detect switch (TDS) and temperature sensor.
When steam generator works, aqueous water from water inlet enter stainless steel tube in, using stainless steel tube after, due to pipe Footpath limit, aqueous water can be caused quickly to heat vaporization, via helical pipe, fully complete heat transfer, finally by go out to steam mouth spray Go out steam.
In the embodiment 6 of the powder material sterilizing-drying conveying cleaning integral system of the present invention, its control device includes This intelligent controller of intelligent controller is a PLC.Sterilizing separator rotary valve 14 be electrically-controlled valve, electrically-controlled valve and Respectively electric signal is connected to PLC to the calandria of its steam heater.Intellectual automatically controlling is implemented by PLC.

Claims (2)

1. a kind of full closed aseptic intelligent integral pharmacy system, device for charging material, gas generator, sterilizing separator, Cleaning device, the sterilizing separator includes a separator and second separator and its corresponding Steam Recovery device, described Separator is a centrifugal cyclone separator, it is characterized in that being arranged with along its axis direction on described its perisporium of centrifugal cyclone separator Water conservancy diversion separates spiral ring flat-plate, and the axial direction line of the bottom of centrifugal cyclone separator and the entrance and exit on top is opened in respectively It is tangent with the rotating curve that the water conservancy diversion separates spiral ring flat-plate respectively.
2. full closed aseptic intelligent integral pharmacy system according to claim 1, is characterized in that the centrifugal cyclone is separated The water conservancy diversion of device separates spiral ring flat-plate, and it is inclined downward or upward obliquely from external diameter side toward internal diameter side.
CN201611012424.5A 2016-11-17 2016-11-17 Fully-closed sterile intelligent integrated pharmaceutical system Pending CN106619122A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611012424.5A CN106619122A (en) 2016-11-17 2016-11-17 Fully-closed sterile intelligent integrated pharmaceutical system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611012424.5A CN106619122A (en) 2016-11-17 2016-11-17 Fully-closed sterile intelligent integrated pharmaceutical system

Publications (1)

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CN106619122A true CN106619122A (en) 2017-05-10

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Country Status (1)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103394260A (en) * 2013-08-10 2013-11-20 江西卓尔金属设备集团有限公司 Smoke dust treating device
CN204220573U (en) * 2014-11-03 2015-03-25 天水华圆医疗器械有限公司 A kind of powder material sterilizing-drying transport cleaning integral system cleaning device
CN105621101A (en) * 2014-11-03 2016-06-01 天水华圆医疗器械有限公司 Powder material sterilization, drying, transportation and cleaning integrated system
CN206566222U (en) * 2016-11-17 2017-10-20 宜春万申制药机械有限公司 A kind of full closed aseptic intelligent integral pharmacy system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103394260A (en) * 2013-08-10 2013-11-20 江西卓尔金属设备集团有限公司 Smoke dust treating device
CN204220573U (en) * 2014-11-03 2015-03-25 天水华圆医疗器械有限公司 A kind of powder material sterilizing-drying transport cleaning integral system cleaning device
CN105621101A (en) * 2014-11-03 2016-06-01 天水华圆医疗器械有限公司 Powder material sterilization, drying, transportation and cleaning integrated system
CN206566222U (en) * 2016-11-17 2017-10-20 宜春万申制药机械有限公司 A kind of full closed aseptic intelligent integral pharmacy system

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