CN106617052A - Composition with effects of protecting liver and dispelling effect of alcohol and application thereof - Google Patents
Composition with effects of protecting liver and dispelling effect of alcohol and application thereof Download PDFInfo
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- CN106617052A CN106617052A CN201611056040.3A CN201611056040A CN106617052A CN 106617052 A CN106617052 A CN 106617052A CN 201611056040 A CN201611056040 A CN 201611056040A CN 106617052 A CN106617052 A CN 106617052A
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- mulberries
- resveratrol
- turmeric
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- 239000000203 mixture Substances 0.000 title claims abstract description 36
- 210000004185 liver Anatomy 0.000 title claims abstract description 27
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 230000000694 effects Effects 0.000 title abstract description 7
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- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 30
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- 150000002212 flavone derivatives Chemical class 0.000 claims description 26
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 claims description 26
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- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
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- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 claims description 2
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- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 206010008479 Chest Pain Diseases 0.000 abstract 1
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- OEGPRYNGFWGMMV-UHFFFAOYSA-N (3,4-dimethoxyphenyl)methanol Chemical compound COC1=CC=C(CO)C=C1OC OEGPRYNGFWGMMV-UHFFFAOYSA-N 0.000 description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 239000007767 bonding agent Substances 0.000 description 4
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- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 240000006859 Jasminum officinale Species 0.000 description 2
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- MKYBYDHXWVHEJW-UHFFFAOYSA-N N-[1-oxo-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propan-2-yl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(C(C)NC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 MKYBYDHXWVHEJW-UHFFFAOYSA-N 0.000 description 2
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- 235000015468 Lycium chinense Nutrition 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
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- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000002460 anti-migrenic effect Effects 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
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- 210000004556 brain Anatomy 0.000 description 1
- 244000309466 calf Species 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a composition with effects of protecting liver and dispelling an effect of alcohol. The composition comprises the following components in parts by weight: 5 to 10 parts of pueraria flavones, 10 to 20 parts of resveratrol, 5 to 10 parts of rhizoma curcumae longae, 20 to 40 parts of soya bean lecithin and 5 to 10 parts of mulberries. By taking the product provided by the invention, the body discomfort symbols after drinking, such as dizziness, migraine, blush, bad hangover, liver discomfort, chest distress and the like after drinking, of a user can be effectively relieved.
Description
Technical field
The present invention relates to functional food or health food, and in particular to one kind contains kudzu root flavone, resveratrol, with guarantor
Liver, the composition of antialcoholism action and its application.
Background technology
Spirits culture occupies an important position in the very long cultural and historical of China, and many refined scholars are in tasting good wine
The literature works of preciousness is left afterwards, scholars also create many wine that for example struggle against centered on drinking and write the poem, the wind such as play a drinking game
Refined game.Wine not only occupies important position, in the world as a kind of special culture carrier in the cultural and historical of China
Also the status of uniqueness is occupied in culture.Spirits culture has penetrated into the every field in human society life, to culture, politics,
Economy, medical treatment suffer from tremendous influence and effect.
In China, white wine is liked due to the mouthfeel of its special instrumentality and mellow fragrance by people, but mistake
Amount is drunk and can occur drunk, not only affects work, more injures body, especially liver.《The Yellow Emperor's Canon of Internal Medicine Plain Questions》In mention:Liver
Here person, organ of general, strategy go out.Liver is one of the five internal organs, main anger, in the courage of six internal organs each other table.The spiritual feelings will of liver and people,
Digest and assimilate, QI-blood circulation, aqueous metabolism, property and reproduction etc. it is closely bound up.The Tang Dynasty Aesculapius's SUN Si miao also once existed《Health is engraved》In
Mention " happy feelings of drinking with snacks, big drink is harmful to the health ".Excessive consumption of alcohol, alcohol can produce reaction to the body of people, stimulate brain and stomach, paralysis
Nerve, makes one the symptoms such as headache, dizziness, vomiting, obnubilation occur, and then makes one to forget oneself.In order to alleviate alcohol to human body
Injury, is developed various liver protections, solution alcohol product.Chinese traditional herbs extract has the excellent of uniqueness in terms of liver-protecting sobering up
Gesture, enjoys people to favor.
CN201310608410.X (CN103564573 A) discloses a kind of sobering up and be combined drink with the health care of nourishing the stomach liver protection
Material, it is formulated by the aqueous extract and a small amount of honey and vitamin C of 7 kinds of Chinese medicines.CN201410641639.8
(CN104435349 A) discloses the composition with facilitating alcohol metabolism and protecting liver effect, and it is by calf blood protein-removed extraction, northern winter worm
Summer grass, mulberries, the fruit of Chinese wolfberry, kudzu root extract composition.But above-mentioned health products come with some shortcomings part, such as raw material type it is excessive,
The problems such as complicated process of preparation, high cost.
The content of the invention
The mesh of the present invention is to overcome the deficiencies in the prior art, there is provided a kind of composition with liver protection, antialcoholism action.Use
Person can effectively alleviate uncomfortable symptom after drinking by taking the application product, such as dizziness after drinking, antimigraine, blush, difficulty of being still drank after a night
It is uncomfortable, uncomfortable in chest etc. by, liver.
The present invention is adopted the following technical scheme that and realizes above-mentioned purpose.
A kind of composition with liver protection, antialcoholism action, including the component of following weight portion:Kudzu root flavone 5-10 parts, in vain
Veratryl alcohol 10-20 parts, turmeric 5-10 parts, soybean lecithin 20-40 parts, mulberries 5-10 parts.
Used as an embodiment of the present invention, the composition includes the component of following weight portion:Kudzu root flavone 6-10 parts, in vain
Veratryl alcohol 12-18 parts, turmeric 5-9 parts, soybean lecithin 25-40 parts, mulberries 6-10 parts.
Used as another embodiment of the invention, the composition includes the component of following weight portion:Kudzu root flavone 6-9 parts,
Resveratrol 12-17 parts, turmeric 6-9 parts, soybean lecithin 28-37 parts, mulberries 7-10 parts.
Used as another embodiment of the invention, the composition includes the component of following weight portion:Kudzu root flavone 6-8 parts,
Resveratrol 12-15 parts, turmeric 5-6 parts, soybean lecithin 26-30 parts, mulberries 6-8 parts.
Used as another embodiment of the invention, the composition includes the component of following weight portion:Kudzu root flavone 7-8 parts,
Resveratrol 14-15 parts, turmeric 5-6 parts, soybean lecithin 26-27 parts, mulberries 6-7 parts.
In above-mentioned composition:The weight portion can be the field of medicaments such as μ g, mg, g, kg known to unit of weight, also may be used
To be its multiple, such as 1/10,1/100,10 times, 100 times.
The kudzu root flavone is the extract of plant elegant jessamine or Pachyrhizua angulatus, and wherein kudzu root flavone content is 2%-6%.The Pueraria lobota
Root flavones is commercially available to be commercially available.
The resveratrol is the extract of giant knotweed or grape, and wherein Resveratrol content is 10%-98%.
The turmeric is the rhizome of turmeric, wherein turmeric cellulose content more than 12%.
The soybean lecithin is the extract of soybean, wherein soybean lecithin content more than 60%.
The mulberries are the fruit ear that is dried of mulberry, wherein mulberries content more than 15%.
Composition of the present invention is to be mixed in proportion to obtain final product by each raw material.Concrete operations are those skilled in the art
The common process grasped.Various formulations, such as granule, pulvis, capsule, tablet can also be made by actual demand.
The present invention also provides application of the above-mentioned composition in functional food and health food.
The present invention also provides a kind of granular preparation containing above-mentioned composition, and it is obtained by the composition of following weight portion:The root of kudzu vine
Flavones 5-10 parts, resveratrol 10-20 parts, turmeric 5-10 parts, soybean lecithin 20-40 parts, mulberries 5-10 parts, prebiotics 50-
80 parts, binding agent;The consumption of the binding agent is the 2%-5% of remaining each component quality sum.
The binding agent is water or alcohol.The concentration of the alcohol is volume ratio 10%-95%.
Used as an embodiment of the present invention, the granular preparation is composed of the following components in parts by weight:Kudzu root flavone 6-10
Part, resveratrol 12-18 parts, turmeric 5-9 parts, soybean lecithin 25-40 parts, mulberries 6-10 parts, prebiotics 60-75 parts, bonding
Agent;The consumption of the binding agent is the 2%-5% of aforementioned component quality sum.
Used as another embodiment of the invention, the granular preparation is composed of the following components in parts by weight:Kudzu root flavone 6-9
Part, resveratrol 12-17 parts, turmeric 6-9 parts, soybean lecithin 28-37 parts, mulberries 7-10 parts, prebiotics 60-75 parts, bonding
Agent;The consumption of the binding agent is the 2%-5% of aforementioned component quality sum.
Used as another embodiment of the invention, the granular preparation includes the component of following weight portion:Kudzu root flavone 6-8
Part, resveratrol 12-15 parts, turmeric 5-6 parts, soybean lecithin 26-30 parts, mulberries 6-8 parts, prebiotics 60-75 parts, bonding
Agent;The consumption of the binding agent is the 2%-5% of aforementioned component quality sum.
Used as another embodiment of the invention, the granular preparation includes the component of following weight portion:Kudzu root flavone 7-8
Part, resveratrol 14-15 parts, turmeric 5-6 parts, soybean lecithin 26-27 parts, mulberries 6-7 parts, prebiotics 60-75 parts, bonding
Agent;The consumption of the binding agent is the 2%-5% of aforementioned component quality sum.
The prebiotics (Probiotics) is isomalto-oligosaccharide, FOS or xylo-oligosaccharide.
Present invention also offers the preparation method of above-mentioned granular preparation, the method is comprised the following steps:
1) prebiotics is pulverized and sieved, chooses fine powder under 40-80 mesh sieves;According to proportioning weigh kudzu root flavone, resveratrol,
Turmeric, soybean lecithin, mulberries, prebiotics fine powder, are well mixed;
2) add water or alcohol as binding agent in the fine powder for mixing, make the particle of 10-60 mesh, be in temperature
It is dried under conditions of 40-60 DEG C, minute drying time 30-90, dispenses, obtains final product.
The composition and its preparation that the present invention is provided has advantages below:
1st, the present invention makes various composition with kudzu root flavone, resveratrol, turmeric, soybean lecithin, mulberries as primary raw material
Reasonable formula, cooperate with shared, by number of ways, at many levels reach the health care of liver-protecting sobering up, are applicable to bad life
The hepatic injury crowd that custom or excessive consumption of alcohol are caused.
2nd, after the preparation that the present invention is provided is reconstituted, color coordination, sweet mouthfeel is moderate, and has the distinctive perfume (or spice) of plant extracts
Gas.
3rd, experiment is passed through, the composition of present invention offer and the volunteer of preparation are taken in discovery, have a headache after excessive consumption of alcohol,
The situations such as dizziness, vomiting, liver discomfort be improved significantly, it is efficient to reach more than 80%.
Specific embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.In following examples:
Kudzu root flavone used is the extract of elegant jessamine, and wherein kudzu root flavone content is 2%-6%, and purchased from Tianjin benefit life is built again
Thing Technology Co., Ltd..
Resveratrol used is the extract of giant knotweed or grape, and wherein Resveratrol content is 10%-98%, purchased from Tianjin
Yi Beijian Bioisystech Co., Ltd.
Turmeric used is the rhizome of turmeric, wherein turmeric cellulose content more than 12%, and building biotechnology again purchased from Tianjin benefit has
Limit company.
Soybean lecithin used is extract of soybean, wherein soybean lecithin content more than 60%, is built again purchased from Tianjin benefit
Bioisystech Co., Ltd.
Mulberries used are dried fruit ear, wherein mulberries content more than 15% for mulberry, and building biotechnology again purchased from Tianjin benefit has
Limit company.
Embodiment 1:
Formula:Kudzu root flavone 6kg, resveratrol 12kg, turmeric 5kg, soybean lecithin 29kg, mulberries 8kg.
Embodiment 2:
Formula:Kudzu root flavone 7kg, resveratrol 12kg, turmeric 5kg, soybean lecithin 30kg, mulberries 6kg.
Embodiment 3:
Formula:Kudzu root flavone 7kg, resveratrol 14kg, turmeric 5kg, soybean lecithin 27kg, mulberries 7kg.
Embodiment 4:
Formula:Kudzu root flavone 8kg, resveratrol 15kg, turmeric 5kg, soybean lecithin 26kg, mulberries 6kg.
Comparative example 1:
Formula:Resveratrol 17kg, turmeric 9kg, soybean lecithin 26kg, mulberries 8kg.
Comparative example 2:
Formula:Kudzu root flavone 17kg, turmeric 8kg, soybean lecithin 34kg, mulberries 9kg.
Comparative example 3:
The existing formula sobered up with nourishing the stomach liver protection:Pachyrhizua angulatus 2000g, honey raisin tree 2000g, FI puerariae 1800g, dark plum 1500g, Buddha's hand
2500g, galangal 1500g, Radix Glycyrrhizae 2000g, honey 2000g and vitamin C 1000g.
Comparative example 4
Formula:Kudzu root flavone 4kg, resveratrol 10kg, turmeric 5kg, soybean lecithin 36kg, mulberries 5kg.
Comparative example 4
Formula:Kudzu root flavone 11kg, resveratrol 9kg, turmeric 5kg, soybean lecithin 29kg, mulberries 6kg.
Granular preparation containing embodiment 1-4 and the composition of comparative example 1-4 is obtained using this area usual manner, its
Middle auxiliary material binding agent is the 3% of active component weight sum.
Experimental example 1:Prove the experiment with anti-aging beauty-care effect of the present invention
1st, crowd selects:
Choose 30~50 years old, Jing is often treated with courtesy, excessive consumption of alcohol crowd, each 180 people of men and women.
2nd, experiment packet
320 volunteers take respectively the product that embodiment 1-4 and comparative example 1-4 are provided, 40 will in 360 volunteers
Hope person does not take any product before and after drinking, used as blank control group.
3rd, experimental technique:According to taking dose, respectively take once before and after drinking every time, each 5g preparations continuously take 3
Month.
4th, experimental result:It is shown in Table 1
Table 1:Physical condition after excessive consumption of alcohol
The result of table 1 shows:
Tested through 3 months, the volunteer of blank control group, headache, vomiting, liver discomfort situation are without bright after excessive consumption of alcohol
It is aobvious to improve;
1 group of embodiment:Have 24 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 60%;
2 groups of embodiment:Have 26 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 65%;
3 groups of embodiment:Have 30 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 75%;
4 groups of embodiment:Have 34 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 85%.
1 group of comparative example:Have 22 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 55%.
2 groups of comparative example:Have 17 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 42.5%.
3 groups of comparative example:Have 19 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 47.5%.
4 groups of comparative example:Have 20 volunteers have a headache after excessive consumption of alcohol, vomit, liver discomfort situation be improved significantly,
It is efficient to reach 50%.
As a result show, the volunteer for taking composition of the present invention uncomfortable situation after drinking improves efficient bright
Aobvious is higher than other contrast groups, illustrates that between composition each component of the present invention synergy can be played, and is being alleviated after drinking not
Suitable aspect obtains remarkable result.
Although above with a general description of the specific embodiments the present invention is described in detail,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, without departing from theon the basis of the spirit of the present invention these modifications or improvements, belong to the scope of protection of present invention.
Claims (10)
1. a kind of composition with liver protection, antialcoholism action, it is characterised in that including the component of following weight portion:Kudzu root flavone
5-10 parts, resveratrol 10-20 parts, turmeric 5-10 parts, soybean lecithin 20-40 parts, mulberries 5-10 parts.
2. composition according to claim 1, it is characterised in that the composition includes the component of following weight portion:Pueraria lobota
Root flavones 6-10 parts, resveratrol 12-18 parts, turmeric 5-9 parts, soybean lecithin 25-40 parts, mulberries 6-10 parts.
3. composition according to claim 1, it is characterised in that the composition includes the component of following weight portion:Pueraria lobota
Root flavones 6-8 parts, resveratrol 12-15 parts, turmeric 5-6 parts, soybean lecithin 26-30 parts, mulberries 6-8 parts.
4. composition according to claim 1, it is characterised in that the composition includes the component of following weight portion:Pueraria lobota
Root flavones 7-8 parts, resveratrol 14-15 parts, turmeric 5-6 parts, soybean lecithin 26-27 parts, mulberries 6-7 parts.
5. application of the arbitrary composition of claim 1-4 in functional food and health food.
6. application according to claim 5, it is characterised in that formulation made by the composition is granule, pulvis, glue
Wafer, tablet.
7. a kind of granular preparation containing the arbitrary composition of claim 1-4, it is characterised in that by following weight portion into
Divide and be obtained:Kudzu root flavone 5-10 parts, resveratrol 10-20 parts, turmeric 5-10 parts, soybean lecithin 20-40 parts, mulberries 5-10
Part, prebiotics 50-80 parts, binding agent;The consumption of the binding agent is the 2%-5% of remaining each component quality sum.
8. granular preparation according to claim 7, it is characterised in that the binding agent is water or alcohol;The alcohol
Concentration is volume ratio 10%-95%.
9. granular preparation according to claim 7, it is characterised in that the prebiotics is isomalto-oligosaccharide, oligomeric fruit
Sugar or xylo-oligosaccharide.
10. the preparation method of granular preparation described in a kind of claim 7-9, it is characterised in that comprise the steps:
1) prebiotics is pulverized and sieved, chooses fine powder under 40-80 mesh sieves;Kudzu root flavone, resveratrol, ginger are weighed according to proportioning
Huang, soybean lecithin, mulberries, prebiotics fine powder, are well mixed;
2) add water or alcohol as binding agent in the fine powder for mixing, make the particle of 10-60 mesh, be 40- in temperature
It is dried under conditions of 60 DEG C, minute drying time 30-90, dispenses, obtains final product.
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CN201611056040.3A CN106617052A (en) | 2016-11-23 | 2016-11-23 | Composition with effects of protecting liver and dispelling effect of alcohol and application thereof |
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CN201611056040.3A CN106617052A (en) | 2016-11-23 | 2016-11-23 | Composition with effects of protecting liver and dispelling effect of alcohol and application thereof |
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Cited By (1)
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CN111375049A (en) * | 2018-12-29 | 2020-07-07 | 辽宁上药好护士药业(集团)有限公司 | Composition for relieving alcoholism and protecting liver as well as preparation method and application thereof |
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CN103385520A (en) * | 2012-05-11 | 2013-11-13 | 张灵芝 | Solid beverage containing Radix Puerariae |
CN103385510A (en) * | 2013-08-05 | 2013-11-13 | 句容茅宝葛业有限公司 | Preparation method for kudzu vine root and mulberry compounded anti-alcoholism beverage |
CN105250997A (en) * | 2015-09-18 | 2016-01-20 | 青岛佰福得科技有限公司 | Composition used for dispelling effects of alcohol and protecting liver, and preparation method thereof |
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CN1895340A (en) * | 2006-06-23 | 2007-01-17 | 易青 | Sobering-up composition |
CN101451097A (en) * | 2007-11-28 | 2009-06-10 | 天津太平洋制药有限公司 | Liver and health preserving wine containing low polyxylose and preparation method thereof |
CN103385520A (en) * | 2012-05-11 | 2013-11-13 | 张灵芝 | Solid beverage containing Radix Puerariae |
CN103385510A (en) * | 2013-08-05 | 2013-11-13 | 句容茅宝葛业有限公司 | Preparation method for kudzu vine root and mulberry compounded anti-alcoholism beverage |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN111375049A (en) * | 2018-12-29 | 2020-07-07 | 辽宁上药好护士药业(集团)有限公司 | Composition for relieving alcoholism and protecting liver as well as preparation method and application thereof |
CN111375049B (en) * | 2018-12-29 | 2023-04-07 | 辽宁上药好护士药业(集团)有限公司 | Composition for relieving alcoholism and protecting liver as well as preparation method and application thereof |
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