CN106614764A - Fly killing agent containing macleaya cordata and cyromazine - Google Patents
Fly killing agent containing macleaya cordata and cyromazine Download PDFInfo
- Publication number
- CN106614764A CN106614764A CN201611159465.7A CN201611159465A CN106614764A CN 106614764 A CN106614764 A CN 106614764A CN 201611159465 A CN201611159465 A CN 201611159465A CN 106614764 A CN106614764 A CN 106614764A
- Authority
- CN
- China
- Prior art keywords
- cyromazine
- macleaya cordata
- fly
- weight
- killing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
- A01N43/68—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms with two or three nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pest Control & Pesticides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to the technical field of veterinary drugs and discloses a fly killing agent containing macleaya cordata and cyromazine. Macleaya cordata and cyromazine are used as active components of the fly killing agent; according to percentage by weight, the weight percentage range of macleaya cordata is 1-5%, and the weight percentage range of cyromazine is 1-10%; in macleaya cordata, the weight percentage of sanguinarine is not less than 1.50%; the total weight percentage of sanguinarine and chelerythrine is not less than 2.25%. Macleaya cordata and cyromazine are matched in use; the cyromazine is used while a certain amount of chelerythrine is added, so that the effects of killing and controlling flies can be improved; the consumption of cyromazine is reduced; the influence on animal organism and environment is reduced; the effects of killing and controlling flies of the fly killing agent are greatly improved; the consumption of cyromazine is effectively reduced; drug pollution and residue can be reduced; the fly killing agent also has the advantages of accelerating parturition, reducing feed conversion ratio, improving animal parturition performance and reducing feeding cost, and has a wide application prospect in the animal farming industry.
Description
Technical field
The present invention relates to the technical field of veterinary drug, more particularly to the fly spray containing macleaya cordata and cyromazine.
Background technology
Fly is one of four pests, and it not only pollutes environment, and is the carrier of virus and bacterium, the numerous disease of the mankind
All there is direct relation with the flies such as fly.In plant, the anti-system of flies is the work of an arduousness and complexity, and medicine is controlled
It is an important means, but the toxicity of the fly spray of the overwhelming majority is larger, and the medicine environmental pollution using rear residual is serious,
Even change the ecosystem.And, most of fly spray is all harmful, has seriously threatened the health of the mankind.
Cyromazine belongs to insecticide, and for controlling the breeding of fly larvae in animal house, cyromazine can suppress dipteron
Mesh larva casts off a skin, particularly the 1st phase larval molting, makes fly maggot breeding be obstructed, and can also prevent the fly larva of a tapeworm or the cercaria of a schistosome dead from casting off a skin.Ring third
The use of ammonia piperazine can substantially reduce ammonia level in hen house, substantially improve its feeding environment, also, the work of cyromazine
Property composition can decompose in soil, environmentally safe, belong to high-efficiency environment friendly medicament.Cyromazine is considered as having no at the beginning of use
The resistance to the action of a drug, can control multiresistance fly strain, and not affected by cross-resistance, can use safely in broiler chicken, breeder, laying hen, pig,
People and animals are had no adverse effects by the animals such as ox, sheep, do not injure fly maggot natural enemy, and are classified as most low toxicity by the World Health Organization (WHO)
Property material.
But, with cyromazine widely using in animal husbandry, it is resistance to that fly has gradually started generation to cyromazine
The property of medicine, causes its addition in feed increasing.During raising, cyromazine spice concentration reaches 25mg/kg, can increase dynamic
Thing feed consumption；More than 1000mg/kg feeds for a long time, then animal may be made very few and dead because ingesting.And, it is substantial amounts of to make
Also there is medicament residue problem with cyromazine, the chicken manure of feeding cyromazine is applied on soil can be affected more than 9 tons of per hectares
The growth of plant.
The content of the invention
It is an object of the invention to provide the fly spray containing macleaya cordata and cyromazine, it is intended to solve ring of the prior art
Third ammonia piperazine fly spray increases because of the excessive and caused medicament residue of addition, feed consumption, or even causes asking for animal dead
Topic.
The present invention is achieved in that the fly spray containing macleaya cordata and cyromazine, and its active component is macleaya cordata and ring
Third ammonia piperazine, calculates in percentage by weight, and the weight percentage ranges of the macleaya cordata are 1%-5%, the cyromazine
Weight percentage ranges are 1%-10%；Bring back described, the percentage by weight of sanguinarine is no less than 1.50%, sanguinarine
2.25% is no less than with the total weight percent of Chelerythrine.
Further, the fly spray containing macleaya cordata and cyromazine is prepared as solid pharmaceutical preparation or liquid by adding auxiliary material
Body preparation.
Further, the solid pharmaceutical preparation containing macleaya cordata and the fly spray of cyromazine is pre-mixing agent or granule.
Further, the liquid preparation containing macleaya cordata and the fly spray of cyromazine is emulsion.
Macleaya cordata has anti-inflammation, appetizing, somatotrophic effect, and there is contained alkaloid desinsection and diseases prevention etc. to act on,
Can make paralysis after fly maggot first excitement and dead, and fly blow can be suppressed to hatch.The going out containing macleaya cordata and cyromazine that the present invention is provided
Fly agent, is to be combined together macleaya cordata and cyromazine, and both Synergistics not only can effectively reduce cyromazine and use
Measure, greatly improve and kill fly control fly effect, reduce drug contamination and residual, reduction to animal body and the injury to environment, and,
Breeding performonce fo animals can also be improved, feedstuff-meat ratio is reduced, is reduced animal feeding cost, there is wide application in animal farming industry
Prospect.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that specific embodiment described herein is not used to only to explain the present invention
Limit the present invention.
It is described in detail below in conjunction with realization of the specific embodiment to the present invention.
The fly spray containing macleaya cordata and cyromazine that the present embodiment is provided, for controlling fly and fly eradication, and can reduce
Impact to animal body and environment.
In the present embodiment, the main active containing macleaya cordata and the fly spray of cyromazine is macleaya cordata and the ammonia of ring third
Piperazine, calculates in percentage by weight, and the weight percentage ranges of macleaya cordata are 1%-5%, the percentage by weight model of cyromazine
Enclose for 1%-10%, wherein, the total weight percent of sanguinarine and Chelerythrine in bringing back is no less than 2.25%, its
In, the percentage by weight of sanguinarine is no less than 1.50%.
In the fly spray containing macleaya cordata and cyromazine of above-mentioned offer, contained macleaya cordata has anthelmintic action and kills
Nematode acts on, and also has suppression effect to some bacterial fungus.Macleaya cordata kills maggot effect, and fly blow can be suppressed to hatch, also, wins
Maggot effect is most strong with leaf and pericarp effect for killing of returning, leaf and pericarp have it is stronger kill bright effect, stem takes second place, and root is most weak, its effect
Do not fail because being dried, active ingredient may be alkaloid, and the anti-inflammation composition of macleaya cordata is ethoxysanguinarine and ethoxy
Base blood bends the red alkali of dish.The sulfate of macleaya cordata total alkaloid has local anaesthesia to act on, similar to the effect of procaine hydrochloride.From
The concentration range of the Biflorine that above-mentioned fly spray is isolated is 0.5 μ g/ml-1.0 μ g/ml, is had significantly to isolated uterine
Contraction.
In fly spray containing macleaya cordata and cyromazine, cyromazine belongs to insecticide, for controlling fly children in animal house
The breeding of worm.Cyromazine can suppress casting off a skin for Diptera larvae, particularly the 1st phase larval molting, make fly maggot breeding be obstructed,
The fly larva of a tapeworm or the cercaria of a schistosome can also be prevented dead from casting off a skin.Cyromazine can control multiresistance fly strain without the resistance to the action of a drug, and not receive cross-resistance
Affect.Cyromazine in the world extensively apply nearly 20 years, so far without any resistance to the action of a drug report, can use safely in broiler chicken,
In the animals such as breeder, laying hen, pig, ox, sheep, people, animal are had no adverse effects, do not injure fly maggot natural enemy, by world health group
Knit (WHO) and be classified as minimum toxicant.Cyromazine can substantially reduce ammonia level in hen house, substantially improve its feeding
Environment.The active component of cyromazine can decompose in soil, environmentally safe, belong to high-efficiency environment friendly medicament.
The fly spray containing macleaya cordata and cyromazine of above-mentioned offer, it uses cooperatively macleaya cordata and cyromazine, and two
Person plays a role together, a certain amount of macleaya cordata is added while using cyromazine and is greatly improved the effect for killing fly control fly
Really, it is possible to reduce cyromazine is used, to animal body and the impact to environment so that fly spray kills fly control fly effect significantly
Lifted, effectively reduce the usage amount of cyromazine, reduce drug contamination and residual, and, also with the effect that promotes production, reduce
The advantages such as feedstuff-meat ratio, raising breeding performonce fo animals, reduction feeding cost, have broad application prospects in animal farming industry.
In the present embodiment, fly spray is prepared into solid pharmaceutical preparation by adding appropriate auxiliary material, for example can be pre-mixing agent or
Person's granule；Liquid preparation can also be prepared into by adding appropriate auxiliary material, the liquid preparation can be emulsion.
Various preparations containing macleaya cordata and the fly spray of cyromazine presented below：
Embodiment one：Pre-mixing agent
Accurately weigh 1 weight portion cyromazine, 2 weight portion macleaya cordata, balance of silica, by equivalent progressively increase method mixing
Uniformly, collection is obtained final product.
Embodiment two：Granule
Accurately weigh 2 weight portion cyromazines, 1 weight portion macleaya cordata, 2 weight portion sodium carboxymethylcelluloses, 10 weight portions
Dextrin, 10 weight portion water, balance of lactose, granulation is obtained final product.
Embodiment three：Emulsion
2 weight portion cyromazines, 5 weight portion macleaya cordata, 58 weight portion ethyl oleates are accurately weighed, uniform mixing, 2 weight
The Tween-80 of part, balance of water is obtained final product in high-pressure homogeneous emulsification.
In order to absolutely prove the present embodiment provide the beneficial effect containing macleaya cordata and the fly spray of cyromazine, by with
The present invention will be further described for lower test example.
Test example one：The test of feeding effect containing macleaya cordata and the fly spray of cyromazine.
Test objective：Whether that verifies the fly spray containing macleaya cordata and cyromazine has growth promoting function.
Test products：Trial drug：The fly spray of pre-mixing agent is prepared as according to embodiment one；Control drug：1% ring third
Ammonia piperazine pre-mixing agent (is provided) by Foshan Zheng Dian Bioisystech Co., Ltd.
Test method：
Select 100 suitable healthy chickens of 3 age in days body weight to be experimental animal, 5 groups are randomly divided into, respectively by embodiment side
Fly spray test group (1-2), 1% cyromazine pre-mixing agent control group (3-4) and blank control group (5) prepared by formula one, per group
20, it is grouped and disposition is shown in Table 1.On-test, claims the body weight of chicken with the end of, calculates the average weight gain of every chicken.
The test of table 1 packet and process
2nd, result of the test：It is shown in Table 2.
The each feeding with medicine effect of table 2 compares
As shown in Table 2：1st, the average weight gain of 2 groups of chickens is apparently higher than 3,4,5 groups, and 2 groups of weightenings are higher than 1 group, and 4 combinations 5
Group difference is not obvious, shows the fly spray containing macleaya cordata and cyromazine that pre-mixing agent is prepared as by present embodiment of the present invention
Really there is the effect for promoting growth of animal.
Test example two：Fly eradication containing macleaya cordata and the fly spray of cyromazine, control fly effect test.
The species and life habit of fly, common fly has housefly, latrine fly, lucilia sericata, major part gold in people's life
Fly, sarcophaga melanura etc..Fly all one's life can divide four-stage, i.e., from the beginning of adult flies mate and oviposit, through ovum->Larva (maggot)->
Pupa->The process of adult flies, this process is only needed 10 days or so, can be shortened when temperature is high.Fly once mates can lay eggs throughout one's life, and one
Only female fly can lay eggs 5-6 time throughout one's life, every time spawning 100-150, and this more than 100 ovum are changed into adult flies after ten days, so one
Fly all one's life can breed thousands of flies.
Test objective：Fly eradication of the checking containing macleaya cordata and the fly spray of cyromazine, control fly effect.
Test products：Trial drug：The fly spray of pre-mixing agent is prepared as according to embodiment one；Control drug：1% ring third
Ammonia piperazine pre-mixing agent (is provided) by Foshan Zheng Dian Bioisystech Co., Ltd.
Test method：The excrement of the chicken after each group of the packet transaction of table 1 feeds 5-7 days is pressed in collection, and it is laid in respectively
In disk, after putting where dark humidity open storage 3 days, closed 10 days with valance, observe the production and living condition of fly, system
The fly quantity that meter grows.
The fly quantity that the different disposal method of table 3 grows compares
2nd, result of the test：It is shown in Table 3.
As shown in Table 3, what the excrement of the chicken for being fed with the fly spray that pre-mixing agent is prepared as by embodiment one was cultivated
Fly quantity shows the present invention containing macleaya cordata and ring third considerably less than 1% cyromazine pre-mixing agent control group and blank control group
Ammonia piperazine fly spray has and good kills fly control fly effect.
Presently preferred embodiments of the present invention is the foregoing is only, not to limit the present invention, all essences in the present invention
Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.
Claims (4)
1. the fly spray of macleaya cordata and cyromazine is contained, it is characterised in that its active component is macleaya cordata and cyromazine, according to
Percentage by weight is calculated, and the weight percentage ranges of the macleaya cordata are 1%-5%, the percentage by weight model of the cyromazine
Enclose for 1%-10%；Bring back described, the percentage by weight of sanguinarine is no less than 1.50%, sanguinarine and Chelerythrine
Total weight percent be no less than 2.25%.
2. the fly spray containing macleaya cordata and cyromazine as claimed in claim 1, it is characterised in that described containing macleaya cordata and ring
The fly spray of the third ammonia piperazine is prepared as solid pharmaceutical preparation or liquid preparation by adding auxiliary material.
3. the fly spray containing macleaya cordata and cyromazine as claimed in claim 2, it is characterised in that described containing macleaya cordata and ring
The solid pharmaceutical preparation of the fly spray of the third ammonia piperazine is pre-mixing agent or granule.
4. the fly spray containing macleaya cordata and cyromazine as claimed in claim 2, it is characterised in that described containing macleaya cordata and ring
The liquid preparation of the fly spray of the third ammonia piperazine is emulsion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611159465.7A CN106614764A (en) | 2016-12-15 | 2016-12-15 | Fly killing agent containing macleaya cordata and cyromazine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611159465.7A CN106614764A (en) | 2016-12-15 | 2016-12-15 | Fly killing agent containing macleaya cordata and cyromazine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106614764A true CN106614764A (en) | 2017-05-10 |
Family
ID=58822725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611159465.7A Pending CN106614764A (en) | 2016-12-15 | 2016-12-15 | Fly killing agent containing macleaya cordata and cyromazine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106614764A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939067A (en) * | 2019-04-11 | 2019-06-28 | 厦门汇承科技有限公司 | Water-soluble cyromazine pre-mixing agent for animals of one kind and preparation method thereof |
| CN115633681A (en) * | 2022-12-21 | 2023-01-24 | 山东国邦药业有限公司 | Cyromazine water-soluble granules and preparation method and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1256873A (en) * | 1998-12-15 | 2000-06-21 | 安庆市茁壮农药有限公司 | Application of macleaya cordata in pesticide preparation |
| CN1386417A (en) * | 2001-05-22 | 2002-12-25 | 王玉万 | Antiparasitic mixture and pre-mixture containing cyromazine and macrolide insect repellents |
| CN101015303A (en) * | 2006-12-25 | 2007-08-15 | 洪云飞 | Plant mosquito-fly pesticide |
| CN101664036A (en) * | 2009-08-26 | 2010-03-10 | 郑州后羿制药有限公司 | Cyromazine liquid preparation and preparation method thereof |
| CN101953380A (en) * | 2010-05-27 | 2011-01-26 | 江苏点金石凹土研究开发有限公司 | Attapulgite maggot-killing powder |
-
2016
- 2016-12-15 CN CN201611159465.7A patent/CN106614764A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1256873A (en) * | 1998-12-15 | 2000-06-21 | 安庆市茁壮农药有限公司 | Application of macleaya cordata in pesticide preparation |
| CN1386417A (en) * | 2001-05-22 | 2002-12-25 | 王玉万 | Antiparasitic mixture and pre-mixture containing cyromazine and macrolide insect repellents |
| CN101015303A (en) * | 2006-12-25 | 2007-08-15 | 洪云飞 | Plant mosquito-fly pesticide |
| CN101664036A (en) * | 2009-08-26 | 2010-03-10 | 郑州后羿制药有限公司 | Cyromazine liquid preparation and preparation method thereof |
| CN101953380A (en) * | 2010-05-27 | 2011-01-26 | 江苏点金石凹土研究开发有限公司 | Attapulgite maggot-killing powder |
Non-Patent Citations (2)
| Title |
|---|
| 王诚，: "灭蝇胺——环丙氨嗪灭蝇效果试验", 《养猪》 * |
| 袁涛忠 等，: "博落回杀灭蝇蛆效果的实验观察", 《中国寄生虫学与寄生虫病杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939067A (en) * | 2019-04-11 | 2019-06-28 | 厦门汇承科技有限公司 | Water-soluble cyromazine pre-mixing agent for animals of one kind and preparation method thereof |
| CN115633681A (en) * | 2022-12-21 | 2023-01-24 | 山东国邦药业有限公司 | Cyromazine water-soluble granules and preparation method and application thereof |
| CN115633681B (en) * | 2022-12-21 | 2023-02-28 | 山东国邦药业有限公司 | Cyromazine water-soluble granules and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| James et al. | Biomedical applications of poisonous plant research | |
| DE69908626T2 (en) | ORAL COMBINATION OF LUFENURON AND NITENPYRAM AGAINST FLAE | |
| EP0255803A1 (en) | Process for the prevention of re-infestation of dogs and cats by fleas | |
| US20120071531A1 (en) | Use of Fungicides for the Treatment of Fish Mycoses | |
| McTier et al. | Evaluation of the effects of selamectin against adult and immature stages of fleas (Ctenocephalides felis felis) on dogs and cats | |
| CN107969445A (en) | A kind of Chinese herbal medicine pesticide | |
| CN101450055A (en) | Soluble powder for treating livestock and poultry bacterial infection and parasitic disease | |
| CN106614764A (en) | Fly killing agent containing macleaya cordata and cyromazine | |
| Anziani et al. | Persistent activity of doramectin and ivermectin in the prevention of cutaneous myiasis in cattle experimentally infested with Cochliomyia hominivorax | |
| KR100236586B1 (en) | 1-[n-(halo-3-pyridylmethyl)]-n-methylamino-2-nitroethylene derivatives for use against fleas on pets | |
| EP3288391B1 (en) | Feed supplement additive | |
| CN101297650A (en) | Agent for preventing and controlling ectoparasite of animals | |
| CN101966197A (en) | Composition for treating bovine severe compound parasitic infection and preparation method thereof | |
| KR20190035860A (en) | Composition comprising Dundtinia plagurans | |
| Sethi et al. | Evaluation of xanthotoxol for central nervous system activity | |
| CN106362058A (en) | Traditional Chinese medicine bath agent for treating duck/goose feather lice and preparation method | |
| CN107157944A (en) | A kind of expelling parasite tablet for animals containing phagostimulant | |
| CN104997805B (en) | A kind of dry powder formulations for preventing and treating saprolegniasis of aquatic animals and its application | |
| CN1784958B (en) | Semi-wild stocking method of musk deers | |
| CN111265538A (en) | Application of periplocin in preparing medicine for killing fish ectoparasite | |
| KR101614814B1 (en) | Composition for controlling house dust mites | |
| CN105145642A (en) | Nematicidal granules containing fosthiazate | |
| CN109329293A (en) | A kind of insecticide acaricide composition containing butene-fipronil and matrine | |
| Gladkih et al. | Prevention of transport stress in the realization of the adaptive potential of pigs | |
| CN106212489A (en) | Pyrifluquinazon and bistrifluron complex composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170510 |
|
| RJ01 | Rejection of invention patent application after publication |