CN1066062C - Medicine for gastroenteritic diseases and its preparation process - Google Patents
Medicine for gastroenteritic diseases and its preparation process Download PDFInfo
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- CN1066062C CN1066062C CN98113858A CN98113858A CN1066062C CN 1066062 C CN1066062 C CN 1066062C CN 98113858 A CN98113858 A CN 98113858A CN 98113858 A CN98113858 A CN 98113858A CN 1066062 C CN1066062 C CN 1066062C
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- rhizoma
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- fructus aurantii
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Abstract
The present invention discloses a medicine for treating gastrointestinal diseases and a preparation method thereof. The medicine has high curative ratio and conspicuous effect, and mainly comprises immature bitter orange, bitter orange, bletilla tuber, cuttlefish bone, etc.
Description
The present invention relates to a kind of medicine for the treatment of gastrointestinal disease and preparation method thereof.
Gastrointestinal disease such as gastric and duodenal ulcers, acute or chronic gastritis, superficial gastritis, abdominal distention, acid regurgitation, stomachache belong to commonly encountered diseases, do not have the medicine of a kind of cure rate height, instant effect in the prior art.
The purpose of this invention is to provide a kind of cure rate height, medicine of significant treatment gastrointestinal disease and preparation method thereof takes effect.
Technical scheme of the present invention is:
A kind of medicine for the treatment of gastrointestinal disease, its recipe ingredient and content thereof following (by weight):
Fructus Aurantii Immaturus: Fructus Aurantii: the Pseudobulbus Bletillae (Rhizoma Bletillae): Endoconcha Sepiae: Rhizoma Coptidis: Radix Scutellariae: Rhizoma Pinelliae Preparata: Bulbus Fritillariae Thunbergii: Rhizoma Zingiberis: Cortex Magnoliae Officinalis: Radix Ginseng: Rhizoma Atractylodis Macrocephalae preparata: Fructus Jujubae: Radix Glycyrrhizae: Ranitidine (ranitidine)=2-10: 2-12: 1-5: 1-5: 1-4: 1-4: 0.6-2: 0.6-3: 0.6-3: 1-3: 1-3: 1-3: 1-2: 4: 0.01-0.03.
Preparation method is as follows:
1, get 75% ethanol and make solvent, Fructus Aurantii Immaturus, Fructus Aurantii are put in the hermetic container, it is an amount of to add ethanol, floods 48 hours, and getting supernatant thereafter, to make tincture standby.
2, Endoconcha Sepiae is put in the clear water and soaked 7-10 days, cleans to there not being stench flavor, dries.
3, Endoconcha Sepiae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Coptidis, Radix Scutellariae, Rhizoma Pinelliae Preparata, Bulbus Fritillariae Thunbergii, Rhizoma Zingiberis, Cortex Magnoliae Officinalis, Radix Ginseng, Rhizoma Atractylodis Macrocephalae preparata, Fructus Jujubae, Radix Glycyrrhizae were soaked two hours, add suitable quantity of water and decoct (slow fire behind the first intense fire) three times (about three hours), get supernatant after the filtration, put another and decoct and to continue in container to decoct, and add Fructus Aurantii Immaturus (shell) tincture and together decoct to moisture and all volatilize, water content is no more than 5% (weight ratio), become thick paste or dried paste, crushed after being dried is crossed 120 mesh sieves, and is standby.
4, with lixiviate, medicine after the pulverizing and Ranitidine put in the trough type mixing machine, fully mix.
For commonly encountered diseases such as gastric and duodenal ulcers, acute or chronic gastritis, superficial gastritis, abdominal distention, acid regurgitation, stomachaches, answer regulating the stomach and sending down the abnormal ascending QI, relieving gastric hyperacidity to alleviate stomachache, relieving accumulation of pathogens to remove painful abdominal mass.Fructus Aurantii Immaturus in the prescription, the Fructus Aurantii toil is slightly cold, and the former hardship is let out hot loosing, and the power of circulation of qi promoting is more violent, expands consumer product dredge stasis so the energy dispelling the stagnated QI removes; Latter's drug effect relaxes, and removes based on promoting the circulation of QI to alleviate the stagnation in middle-JIAO and expands, and the two compatibility is we's monarch drug altogether; Endoconcha Sepiae, Bulbus Fritillariae Thunbergii have the effect of convergence, antacid, pain relieving, and it is the ministerial drug of side that Pseudobulbus Bletillae (Rhizoma Bletillae) astringing to arrest bleeding, reducing swelling and alleviating pain three share the merit that becomes auxiliary altogether; Rhizoma Coptidis, Radix Scutellariae bitter cold are fallen and are let out except that its heat, and Rhizoma Pinelliae Rhizoma Zingiberis Xin Wenkai ties cold expelling, Cortex Magnoliae Officinalis promoting the circulation of QI to remove dampness removing food stagnancy, Radix Ginseng, Rhizoma Atractylodis Macrocephalae the spleen strengthening and damp drying, Fructus Jujubae Radix Glycyrrhizae invigorating the spleen and replenishing QI with in become assistant to make it merit altogether; To reach regulating the stomach and sending down the abnormal ascending QI, relieving gastric hyperacidity to alleviate stomachache, relieving accumulation of pathogens removes the effect of painful abdominal mass.
Advantage of the present invention and good effect are:
To gastrointestinal disease such as gastric and duodenal ulcers, acute or chronic gastritis, superficial gastritis, abdominal distention, acid regurgitation, stomachaches, the cure rate height takes effect significantly, side effect is little, reasonable recipe, and can be made into multiple dosage form, the convenient use, preparation method is easy, is convenient to large-scale industrial production.
Below in conjunction with embodiment the present invention is done further detailed description:
Embodiment 1 component and content thereof following (by weight):
Fructus Aurantii Immaturus: Fructus Aurantii: the Pseudobulbus Bletillae (Rhizoma Bletillae): Endoconcha Sepiae: Rhizoma Coptidis: Radix Scutellariae: Rhizoma Pinelliae Preparata: Bulbus Fritillariae Thunbergii: Rhizoma Zingiberis: Cortex Magnoliae Officinalis: Radix Ginseng: Rhizoma Atractylodis Macrocephalae preparata: Fructus Jujubae: Radix Glycyrrhizae: Ranitidine (ranitidine)=2: 2: 1: 1: 1: 1: 0.6: 0.6: 0.6: 1: 1: 1: 1: 4: 0.01.
Embodiment 2 components and content thereof following (by weight):
Fructus Aurantii Immaturus: Fructus Aurantii: the Pseudobulbus Bletillae (Rhizoma Bletillae): Endoconcha Sepiae: Rhizoma Coptidis: Radix Scutellariae: Rhizoma Pinelliae Preparata: Bulbus Fritillariae Thunbergii: Rhizoma Zingiberis: Cortex Magnoliae Officinalis: Radix Ginseng: Rhizoma Atractylodis Macrocephalae preparata: Fructus Jujubae: Radix Glycyrrhizae: Ranitidine (ranitidine)=10: 12: 5: 5: 4: 4: 2: 3: 3: 3: 3: 3: 2: 4: 0.03.
Embodiment 3 components and content thereof following (by weight):
Fructus Aurantii Immaturus: Fructus Aurantii: the Pseudobulbus Bletillae (Rhizoma Bletillae): Endoconcha Sepiae: Rhizoma Coptidis: Radix Scutellariae: Rhizoma Pinelliae Preparata: Bulbus Fritillariae Thunbergii: Rhizoma Zingiberis: Cortex Magnoliae Officinalis: Radix Ginseng: Rhizoma Atractylodis Macrocephalae preparata: Fructus Jujubae: Radix Glycyrrhizae: Ranitidine (ranitidine)=6: 7: 3: 3: 2.5: 2.5: 1.3: 1.8: 1.8: 2: 2: 2: 1.5: 4: 0.02.
Preparation method is as follows:
1, get 75% ethanol and make solvent, Fructus Aurantii Immaturus, Fructus Aurantii are put in the hermetic container, it is an amount of to add ethanol, floods 48 hours, and getting supernatant thereafter, to make tincture standby.
2, Endoconcha Sepiae is put in the clear water and soaked 7-10 days, cleans to there not being stench flavor, dries.
3, with Endoconcha Sepiae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Coptidis, Radix Scutellariae, Rhizoma Pinelliae Preparata, Bulbus Fritillariae Thunbergii, soaked two hours in Rhizoma Zingiberis Recens, Cortex Magnoliae Officinalis, Radix Ginseng, Rhizoma Atractylodis Macrocephalae preparata, Fructus Jujubae, Radix Glycyrrhizae, add suitable quantity of water and decoct (slow fire behind the first intense fire) three times (about three hours), get supernatant after the filtration, put another and decoct and to continue in container to decoct, and add Fructus Aurantii Immaturus (shell) tincture and together decoct to moisture and all volatilize, water content is no more than 5% (weight ratio), become thick paste or dried paste, crushed after being dried is crossed 120 mesh sieves, and is standby.
4, with lixiviate, medicine after the pulverizing and Ranitidine put in the trough type mixing machine, are filled in the O# capsule after fully mixing.The content of Ranitidine in every capsules (ranitidine) must not be above 50 milligrams.
Instructions of taking:
Oral, a day clothes secondary is once obeyed 3, and the patient with slight symptoms can be cut down according to the circumstance or be followed the doctor's advice and take.
Its treatment rule of prescription of making a general survey of the Chinese traditional treatment the spleen-stomach disease is mostly with soothing the liver strong (reason) spleen, and invigorating spleen to remove dampness (dampness), invigorating the spleen and regulating the stomach are main, its used medicine is also mostly to be to strengthen the spleen and stomach or the agent of soothing the liver reason spleen, and the composition of prescription of the present invention is filled a prescription from it, effect, and curing mainly all has its original novel part.
The first, it both had been not limited to the method for capturing of Zhang Zihe, also was different from the opinion of Lee east wall tonifying the spleen and stomach, but at this traditional Chinese medical science disease of gastric abscess, in conjunction with the understanding of modern medicine to the gastric and duodenal ulcers disease, the old complaint of directly hitting, utilization regulating the stomach and sending down the abnormal ascending QI, relieving gastric hyperacidity to alleviate stomachache in the legislation, relieving accumulation of pathogens removes painful abdominal mass; Prescription is reused Fructus Aurantii Immaturus on forming, and Fructus Aurantii removes painful abdominal mass to reach the dispelling the stagnated QI removing food stagnancy; With Bulbus Fritillariae Thunbergii, Endoconcha Sepiae, Pseudobulbus Bletillae (Rhizoma Bletillae) relieving gastric hyperacidity to alleviate stomachache, detumescence and promoting granulation; The assistant Rhizoma Coptidis, the cold and heat of letting out stomach fall in bitter cold such as Radix Scutellariaes etc. first, and second the modern medicine science has recognized that Rhizoma Coptidis its berberine (berberine) composition after extracting has killing and suppresses the effect of campylobacter pyloridis; Radix Ginseng, Rhizoma Atractylodis Macrocephalae preparata, Fructus Jujubae, Radix Glycyrrhizae Preparata to alleviate, prevent the sending an expedition against too of monarch, minister, adjuvant drug, reinforcement and elimination in combination as messenger drug, bring out the best in each other.
The second, the Chinese medicine and western medicine compatibility is applied to treat the another big characteristics that gastric abscess is this side simultaneously.
Gastric abscess, be diseases such as modern medicine indication gastric and duodenal ulcers, acute or chronic gastritis, skin ulcer and gastritis, and pathogen disturbing the stomach and intestines, intermingling cold and heat, due to the lifting imbalance, and modern medicine discovering in recent years thought, the formation of gastric and duodenal ulcers disease is due to campylobacter pyloridis corrodes, thereby the inventor in clinical practice in conjunction with oneself for many years in the experience of treatment gastropathy, scientifically, learn wildly from other's strong points neatly, learn something in history and mud not, on the basis of inheriting, discard the dross and select the essence; Organically Chinese medicine and pharmacy and present-day medical knowledge are combined, be used to instruct clinical practice to obtain good effect.For example: the Fructus Aurantii Immaturus among this side, Fructus Aurantii is extracted the effect that fluid extract has inhibition histamine of making through processing; It is more satisfactory antacid that Endoconcha Sepiae is rich in calcium carbonate, berberine in the Rhizoma Coptidis has killing and suppresses to colonize in the effect of campylobacter pyloridis in the intestines and stomach, Ranitidine has the effect of competitive inhibition histamine and H2 receptors bind, and adds the healing that Ranitidine 50mg to 150mg compatibility can promote gastric and duodenal ulcers effectively in adult's oral dose each time.The Chinese medicine and western medicine compatibility is jointly in treatment stomach sending down the abnormal ascending QI, relieving accumulation of pathogens removes painful abdominal mass, tonifying the spleen and stomach, QI invigorating and in effect, use Ranitidine not only to improve clinical efficacy but also can reduce or eliminate it and take the untoward reaction that human body is caused for a long time in right amount, exactly according to different disease types simultaneously.
Creativeness of the present invention further will illustrate in clinical report.
Claims (1)
1. product for the treatment of gastrointestinal disease is characterized in that it is formed by the feedstock production of following consumption proportion: Fructus Aurantii Immaturus: Fructus Aurantii: the Pseudobulbus Bletillae (Rhizoma Bletillae): Endoconcha Sepiae: Rhizoma Coptidis: Radix Scutellariae: Rhizoma Pinelliae Preparata: Bulbus Fritillariae Thunbergii: Rhizoma Zingiberis: Cortex Magnoliae Officinalis: Radix Ginseng: Rhizoma Atractylodis Macrocephalae preparata: Fructus Jujubae: Radix Glycyrrhizae: ranitidine=(2-10): (2-12): (1-5): (1-5): (1-4): (1-4): (0.6-2): (0.6-3): (0.6-3): (1-3): (1-3): (1-3): (1-2): 4: (0.01-0.03).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98113858A CN1066062C (en) | 1998-03-24 | 1998-03-24 | Medicine for gastroenteritic diseases and its preparation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98113858A CN1066062C (en) | 1998-03-24 | 1998-03-24 | Medicine for gastroenteritic diseases and its preparation process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1198948A CN1198948A (en) | 1998-11-18 |
| CN1066062C true CN1066062C (en) | 2001-05-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN98113858A Expired - Fee Related CN1066062C (en) | 1998-03-24 | 1998-03-24 | Medicine for gastroenteritic diseases and its preparation process |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1299756C (en) * | 2005-09-05 | 2007-02-14 | 郑巨安 | Stomach-benefiting medicine and its prepn |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100488559C (en) * | 2005-09-30 | 2009-05-20 | 中国科学院长春应用化学研究所 | Preparation of Chinese medicinal composition for treating chronic atrophic gastritis |
| CN101450192B (en) * | 2007-07-28 | 2011-03-23 | 马希文 | Medicine of heat syndrome of acid regurgitation disease |
| CN103536764A (en) * | 2013-10-14 | 2014-01-29 | 臧云彩 | Traditional Chinese medicine used for treating digestive system ulcer |
| CN111228405B (en) * | 2020-03-31 | 2022-08-23 | 张京平 | A Chinese medicinal composition for treating gastrointestinal diseases, and its preparation method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092297A (en) * | 1993-03-13 | 1994-09-21 | 张逢彪 | A kind of medicine for the treatment of stomach, duodenal ulcer |
-
1998
- 1998-03-24 CN CN98113858A patent/CN1066062C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092297A (en) * | 1993-03-13 | 1994-09-21 | 张逢彪 | A kind of medicine for the treatment of stomach, duodenal ulcer |
Non-Patent Citations (1)
| Title |
|---|
| 《实用中西医结合杂志》，第9卷第1期 1996.1.1 阮华良等:"中西医结合治疗消化性溃疡19例疗效观察" * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1299756C (en) * | 2005-09-05 | 2007-02-14 | 郑巨安 | Stomach-benefiting medicine and its prepn |
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| Publication number | Publication date |
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| CN1198948A (en) | 1998-11-18 |
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