CN1772202A - Gastrointestinal disease treating medicine and its production process - Google Patents
Gastrointestinal disease treating medicine and its production process Download PDFInfo
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- CN1772202A CN1772202A CNA2005100470648A CN200510047064A CN1772202A CN 1772202 A CN1772202 A CN 1772202A CN A2005100470648 A CNA2005100470648 A CN A2005100470648A CN 200510047064 A CN200510047064 A CN 200510047064A CN 1772202 A CN1772202 A CN 1772202A
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Abstract
The medicine for treating gastrointestinal diseases is prepared with 11 kinds of Chinese medicinal materials, including bletilla tuber, cuttlebone, chicken's gizzard membrane, egg shell, frankincense, etc in certain weight proportion. The preparation process of the medicine includes the following steps: preparing fine powder with 7 kinds of Chinese medicinal materials; alcohol percolating 2 kinds of Chinese medicinal materials to obtain the first extractum; water decocting 2 kinds of Chinese medicinal materials to obtain the second extractum; and mixing the fine powder, the first extractum and the second extractum to obtain the medicine. The medicine of the present invention has obvious curative effect on gastroduodenal ulcer, gastritis, stomachache and other gastrointestinal diseases and no toxic side effect.
Description
Technical field:
The present invention relates to medical science, a kind of medicine and production technology thereof for the treatment of gastrointestinal disease is provided especially.
Background technology:
In the prior art, the medicine of treatment gastropathy is a lot, and drug effect has nothing in common with each other but be close substantially.People expect the medicine of diseases such as the novel syndrome of stagnation of QI that is used for the treatment of gastric abscess and syndrome of blood stasis, gastric and duodenal ulcers, chronic gastritis.Require to meet the correlated quality standard-required fully, processing technology is advantages of simple more, and effect is more stable and good.
Summary of the invention:
The purpose of this invention is to provide a kind of medicine and production technology thereof for the treatment of gastrointestinal disease.
The invention provides a kind of medicine for the treatment of gastrointestinal disease, it is characterized in that: its medicine by following compositions and corresponding mass umber content makes:
Pseudobulbus Bletillae (Rhizoma Bletillae): 50～75; Endoconcha Sepiae: 50～75; Rhizoma Cyperi: 50～75; The Radix Astragali: 50～75; The Radix Paeoniae Alba: 50～75; Radix Notoginseng: 50～75; Endothelium Corneum Gigeriae Galli: 30～46; Ovum crusta Gallus domesticus (parching to brown): 0.2～2; Olibanum: 25～40; Myrrha: 10～20; Pulvis Fumi Carbonisatus: 8～18.
A kind of medicine production technology for the treatment of gastrointestinal disease as mentioned above of the present invention is characterized in that:
Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus made fine powder respectively or mix after make fine powder together; Preferably: before Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus being made fine powder, raw material is made processing only; Carry out sterilization treatment after making fine powder.
Rhizoma Cyperi and Radix Notoginseng are used ethanol percolation, with the thick extractum of percolate simmer down to.Preferably: Rhizoma Cyperi and Radix Notoginseng are made into coarse powder earlier with before the ethanol percolation, use ethanol moistening then, specific operation process can be: selecting 1～3 times of weight, concentration for use is 50～95% ethanol, and the moistening time is 0.5～5 hour.Rhizoma Cyperi and Radix Notoginseng packed into carry out in the percolation jar preferably before the percolation soaking into ethanol then with ethanol is moistening earlier, soak into that to select concentration for use be 50～95% ethanol, infiltrating time is 5～70 hours (preferred 10～30 hours).
With the concrete operations of carrying out percolation in the percolation jar of packing into of Rhizoma Cyperi and Radix Notoginseng be: with 2～10 times of drug weight, concentration be 50～95% ethanol once or be divided into 2～16 times and in the percolation jar, add.The percolation flow velocity per hour is preferably 0.005～0.04 cubic metre, concentrates after then above-mentioned percolate being filtered and makes thick extractum.Method for optimizing: residue medicinal residues behind the percolation are decocted with water 1～3 time, add 2～10 times of weight of water at every turn, each decocting time is 0.5～5 hour, then above-mentioned decocting liquid is filtered the thick extractum of back simmer down to.Described thick extractum preferably under 55～65 ℃ of conditions relative density be 1.1～1.2.
The Radix Astragali, the Radix Paeoniae Alba are decocted with water, with decocting liquid simmer down to thick paste; The preferred process method: it is 1～6 time that the Radix Astragali, the Radix Paeoniae Alba are decocted with water number of times, and each amount of water is 3～20 times of drug weight.Further preferably: the Radix Astragali, the Radix Paeoniae Alba are decocted with water 3 times, add 8～12 times of weight of water first, soaked 2～4 hours, boil and boil 2～4 hours; For the second time add 6～10 times of weight of water, decocted 1.5～3 hours; Add 4～8 times of weight of water for the third time, decocted 0.5～2 hour, then decocting liquid is filtered back simmer down to thick paste.Described thick paste preferably under 55～65 ℃ of conditions relative density be 1.2～1.25.
The thick extractum that will obtain by Rhizoma Cyperi, Radix Notoginseng and merge then by the thick paste that the Radix Astragali, the Radix Paeoniae Alba obtain, and add the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, can make medicine.Preferred process method: above two kinds of thick pastes are merged, and add mix homogeneously behind the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, we can make different disposal according to the needs of different dosage form then, are exemplified below:
To write out a prescription Chinese crude drug through all extracting or extracting section, and other pulverizing medicinal materials concentrates, and drying is made granule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make soft capsule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make powder or capsule; The Chinese crude drug of will writing out a prescription is made pill through operations such as extraction or pulverizing; Chinese crude drug extract or medicated powder and the suitable substrate of will writing out a prescription is made suppository; To write out a prescription Chinese crude drug fine powder and an amount of the adhesive stickiness of medical material itself (or utilize) made the lozenge of regulation shape.
Function of the present invention cures mainly:
Benefiting stomach and stopping pain, clots absorbing hemostasis, antacid.Be mainly used in the syndrome of stagnation of QI and the syndrome of blood stasis of gastric abscess, stomach, duodenal ulcer, chronic gastritis, upper gastrointestinal hemorrhage.
The invention belongs to a clinical line medication, the qi depression to blood stasis that reveals at clinical gastropathy multilist in the side and due to stomach lose moisten foster so that the positive QI-insufficiency of taste and lose the merit of transporting and transforming nutrients from foodstuff, the acid regurgitation belch is subjected to evil the criminal oh.Take benefiting stomach and stopping pain, clots absorbing hemostasis, controlled sour rule of treatment, simultaneously, from symptomatic treatment in acute condition, the dispensing of radical treatment in chronic case principle.
The present invention is directed to gastroxia and be and cause a therefore crux of sick main diseases such as gastric ulcer, Fang Zhongxuan Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae are monarch drug, control its mark, with astringing to arrest bleeding, antacid, to hold back skin ulcer be first main points, Pseudobulbus Bletillae (Rhizoma Bletillae) can promote the renewal of gastric mucosal cell and the healing of mucosa, quickens gastric secretion, prevent that H+ from bleeding back, Endoconcha Sepiae is intended to get that its merit specially restrains, the characteristic of relieving gastric hyperacidity to alleviate stomachache, makes the ulcer kitchen range avoid the erosion of gastric acid, so that it heals early.
Then throwing Rhizoma Cyperi, the Radix Astragali, the Radix Paeoniae Alba, Radix Notoginseng is ministerial drug, with promoting QI circulation for relieving depression, nourishing blood for regulating menstruation, the dissipating blood stasis hemostasis, expelling pus and promoting granulation is strengthened the therapeutic effect of monarch drug, simultaneously again with its circulation of qi promoting, invigorate blood circulation, dissipating blood stasis, pain relieving be purpose, Zhi Qiben is second main points.The Radix Astragali is set upright QI invigorating, promoting pus discharge and tissue regeneration strengthening.Reach eliminating evil and just do not hinder, convergence and do not stay heresy improves local nutrition, gastric acid inhibitory secretion, inflammation is oozed out, promote to organize wound repair, delay gastric emptying and help neutralization and the dilution of food and antiacid medicine, the little hardship of Rhizoma Cyperi acrid in the mouth gastric acid, the property partially the temperature, go into liver and tri-jiao channel, the relieving distension of regulating the flow of vital energy, the spleen strengthening and damp drying.Radix Paeoniae Alba benefiting QI and nourishing blood, strengthening vital QI to eliminate pathogenic factors, pseudo-ginseng blood-circulation-invigovating blood stasis dispelling, hemostasia and promoting granulation, healing up sore and relieving pain.
Throw Endothelium Corneum Gigeriae Galli, Olibanum, Myrrha in the side again, be adjuvant drug, strengthen the monarch and his subjects' medicine promoting blood circulation and stopping pain, detumescence and promoting granulation, hold back the effect of skin ulcer, Endothelium Corneum Gigeriae Galli invigorating the stomach and promoting digestion, the pain relieving of Olibanum Myrrha promoting flow of QI and blood.Ovum crusta Gallus domesticus (parching to brown), Pulvis Fumi Carbonisatus are messenger drug, Ovum crusta Gallus domesticus (parching to brown) antacid, Pulvis Fumi Carbonisatus hemostasis, removing food stagnancy.
Full side establishes the rule of treatment because of specimen, selects medicine rigorous and motivated, and the emergency of making a distinction between the important and the lesser one is degree of having respectively, faces the kind medicine of disease good recipe beneficence.
The corresponding experiment of the present invention shows:
Test through pharmacology pharmacodynamic: Weikang capsule for curing gastric disease has vital energy regualting and blood circulation-promoting, antacid, analgesic effect preferably; can improve the pH value of gastric juice effectively; reduce pepsin activity; the protection gastric mucosa is removed stimulation and the erosion of gastric acid to ulcer surface; remove the coat of the stomach muscle spasm; alleviate stomachache rapidly, dwindle the ulcer area, promote stomach and duodenal tissue regeneration that good effect is arranged.
Weikang capsule for curing gastric disease also has the QI invigorating of setting upright simultaneously, nourishes blood, and improves local nutrition, blood-activating analgetic, and blood activating and promoting tissue regeneration, promoting digestion and removing stagnation is removed gastric acid, distension, the effect of symptoms such as burning.
To the treatment gastric and duodenal ulcers, gastritis, stomachache, gastrorrhagia and hyperchlorhydria, stomach, abdominal distention gas, diseases such as food stagnation have significant curative effect.The present invention examines or check through toxicology, has no side effect.
The present invention can keep the medicine active ingredient to greatest extent, and curative effect of medication is demonstrated fully.Prove that through clinic trial effective percentage improves greatly, cure rate has also reached unprecedented height.
The present invention has treating both the principal and secondary aspects of a disease in terms of existing technologies, suddenly takes stopgap measures, slow effecting a permanent cure, and based on antacid, be good for the stomach, the merit of function of spleen and stomach regulating fortuneization, the flavour of a drug input is reasonable, keen-witted and capable, evident in efficacy.
The specific embodiment:
Embodiment 1
A kind of medicine for the treatment of gastrointestinal disease, its medicine by following compositions and corresponding mass umber content makes: Pseudobulbus Bletillae (Rhizoma Bletillae): 50～75; Endoconcha Sepiae: 50～75; Rhizoma Cyperi: 50～75; The Radix Astragali: 50～75; The Radix Paeoniae Alba: 50～75; Radix Notoginseng: 50～75; Endothelium Corneum Gigeriae Galli: 30～46; Ovum crusta Gallus domesticus (parching to brown): 0.2～2; Olibanum: 25～40; Myrrha: 10～20; Pulvis Fumi Carbonisatus: 8～18.
Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus made fine powder respectively or mix after make fine powder together;
Rhizoma Cyperi and Radix Notoginseng are used ethanol percolation, with the thick extractum of percolate simmer down to;
The Radix Astragali, the Radix Paeoniae Alba are decocted with water, with decocting liquid simmer down to thick paste;
The thick extractum that will obtain by Rhizoma Cyperi, Radix Notoginseng and merge then by the thick paste that the Radix Astragali, the Radix Paeoniae Alba obtain, and add the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, mix homogeneously, we can make different disposal according to the needs of different dosage form then:
To write out a prescription Chinese crude drug through all extracting or extracting section, and other pulverizing medicinal materials concentrates, and drying is made granule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make soft capsule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make powder or capsule; The Chinese crude drug of will writing out a prescription is made pill through operations such as extraction or pulverizing; Chinese crude drug extract or medicated powder and the suitable substrate of will writing out a prescription is made suppository; To write out a prescription Chinese crude drug fine powder and an amount of the adhesive stickiness of medical material itself (or utilize) made the lozenge of regulation shape.
Embodiment 2
A kind of medicine for the treatment of gastrointestinal disease, its medicine by following compositions and corresponding mass umber content makes: Pseudobulbus Bletillae (Rhizoma Bletillae): 50～75; Endoconcha Sepiae: 50～75; Rhizoma Cyperi: 50～75; The Radix Astragali: 50～75; The Radix Paeoniae Alba: 50～75; Radix Notoginseng: 50～75; Endothelium Corneum Gigeriae Galli: 30～46; Ovum crusta Gallus domesticus (parching to brown): 0.2～2; Olibanum: 25～40; Myrrha: 10～20; Pulvis Fumi Carbonisatus: 8～18.
The medicine production technology of described treatment gastrointestinal disease is as follows:
Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus made fine powder respectively or mix after make fine powder together; Before Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus being made fine powder, raw material is made processing only; Carry out sterilization treatment after making fine powder.
Rhizoma Cyperi and Radix Notoginseng are made coarse powder earlier, use ethanol moistening then: selecting 1～3 times of weight, concentration for use is 50～95% ethanol, and the moistening time is 0.5～5 hour; Then Rhizoma Cyperi and Radix Notoginseng are packed into and soak into ethanol in the percolation jar, soak into that to select concentration for use be 50～95% ethanol, infiltrating time is 5～70 hours (preferred 10～30 hours); Then Rhizoma Cyperi and Radix Notoginseng are used ethanol percolation: with 2～10 times of drug weight, concentration be 50～95% ethanol once or be divided into 2～16 times and in the percolation jar, add, the percolation flow velocity per hour is preferably 0.005～0.04 cubic metre, concentrates after then above-mentioned percolate being filtered and makes thick extractum.Residue medicinal residues behind the percolation are decocted with water 1～3 time, add 2～10 times of weight of water at every turn, each decocting time is 0.5～5 hour, then above-mentioned decocting liquid is filtered the thick extractum of back simmer down to.Alkali liquor can be treated to thick extractum with percolate.(the above processing procedure of Rhizoma Cyperi and Radix Notoginseng can be carried out separately, thicker extractum is merged at last; Also can handle together after both mixing.) described thick extractum preferably under 55～65 ℃ of conditions relative density be 1.1～1.2.
The Radix Astragali, the Radix Paeoniae Alba are decocted with water 1～6 time, and each amount of water is 3～20 times of drug weight.Preferably: the Radix Astragali, the Radix Paeoniae Alba are decocted with water 3 times, add 8～12 times of weight of water first, soaked 2～4 hours, boil and boil 2～4 hours; For the second time add 6～10 times of weight of water, decocted 1.5～3 hours; Add 4～8 times of weight of water for the third time, decocted 0.5～2 hour, then decocting liquid is filtered back simmer down to thick paste.(the above processing procedure of the Radix Astragali, the Radix Paeoniae Alba can be carried out separately, thick paste is merged at last again; Also can handle together after both mixing.) described thick paste preferably under 55～65 ℃ of conditions relative density be 1.2～1.25.
The thick extractum that will obtain by Rhizoma Cyperi, Radix Notoginseng and merge then by the thick paste that the Radix Astragali, the Radix Paeoniae Alba obtain, and add the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, mix homogeneously, we can be according to the needs of different dosage form then, make different disposal, be exemplified below:
To write out a prescription Chinese crude drug through all extracting or extracting section, and other pulverizing medicinal materials concentrates, and drying is made granule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make soft capsule; To write out a prescription Chinese crude drug through all or part of pulverizing, and other parts are extracted, and make powder or capsule; The Chinese crude drug of will writing out a prescription is made pill through operations such as extraction or pulverizing; Chinese crude drug extract or medicated powder and the suitable substrate of will writing out a prescription is made suppository; To write out a prescription Chinese crude drug fine powder and an amount of the adhesive stickiness of medical material itself (or utilize) made the lozenge of regulation shape.
Claims (10)
1, a kind of medicine for the treatment of gastrointestinal disease is characterized in that: its medicine by following compositions and corresponding mass umber content makes:
Pseudobulbus Bletillae (Rhizoma Bletillae): 50～75; Endoconcha Sepiae: 50～75; Rhizoma Cyperi: 50～75; The Radix Astragali: 50～75; The Radix Paeoniae Alba: 50～75; Radix Notoginseng: 50～75; Endothelium Corneum Gigeriae Galli: 30～46; Ovum crusta Gallus domesticus (parching to brown): 0.2～2; Olibanum: 25～40; Myrrha: 10～20; Pulvis Fumi Carbonisatus: 8～18.
2, a kind of medicine production technology for the treatment of gastrointestinal disease according to claim 1 is characterized in that:
Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus are made fine powder;
Rhizoma Cyperi and Radix Notoginseng are used ethanol percolation, with the thick extractum of percolate simmer down to;
The Radix Astragali, the Radix Paeoniae Alba are decocted with water, with decocting liquid simmer down to thick paste;
Then above two kinds of thick pastes are merged, and add the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, can make described medicine.
3, according to the medicine production technology of the described treatment gastrointestinal disease of claim 2, it is characterized in that:
Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus are made fine powder before raw material is made processing only; Carry out sterilization treatment after making fine powder.
4, according to the medicine production technology of the described treatment gastrointestinal disease of claim 2, it is characterized in that:
Rhizoma Cyperi and Radix Notoginseng are made into coarse powder earlier with before the ethanol percolation, use ethanol moistening then, specific operation process is: selecting 1～3 times of weight, concentration for use is 50～95% ethanol, and the moistening time is 0.5～5 hour.
5, according to the medicine production technology of the described treatment gastrointestinal disease of claim 4, it is characterized in that:
Rhizoma Cyperi and Radix Notoginseng packed into carry out soaking into ethanol then with ethanol is moistening earlier before the percolation in the percolation jar; It is 50～95% ethanol that concentration is selected in infiltration for use, and infiltrating time is 5～70 hours (preferred 10～30 hours).
6, according to the medicine production technology of claim 4 or 5 described treatment gastrointestinal disease, it is characterized in that:
With the concrete operations of carrying out percolation in the percolation jar of packing into of Rhizoma Cyperi and Radix Notoginseng be: with 2～10 times of drug weight, concentration be 50～95% ethanol once or be divided into 2～16 times and in the percolation jar, add.
7, according to the medicine production technology of the described treatment gastrointestinal disease of claim 6, it is characterized in that:
Residue medicinal residues behind the percolation are decocted with water 1～3 time, add 2～10 times of weight of water at every turn, each decocting time is 0.5～5 hour, then above-mentioned decocting liquid is filtered the thick extractum of back simmer down to.
8, according to the medicine production technology of the described treatment gastrointestinal disease of claim 2, it is characterized in that:
It is 1～6 time that the Radix Astragali, the Radix Paeoniae Alba are decocted with water number of times, and each amount of water is 3～20 times of drug weight.
9, according to the medicine production technology of the described treatment gastrointestinal disease of claim 8, it is characterized in that: the Radix Astragali, the Radix Paeoniae Alba are decocted with water 3 times, add 8～12 times of weight of water first, soaked 2～4 hours, boil and boil 2～4 hours; For the second time add 6～10 times of weight of water, decocted 1.5～3 hours; Add 4～8 times of weight of water for the third time, decocted 0.5～2 hour, then decocting liquid is filtered back simmer down to thick paste.
10, according to the medicine production technology of the described treatment gastrointestinal disease of claim 2, it is characterized in that: the thick extractum that will obtain by Rhizoma Cyperi, Radix Notoginseng and merge by the thick paste that the Radix Astragali, the Radix Paeoniae Alba obtain, and add the fine powder of making by Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae, Endothelium Corneum Gigeriae Galli, Ovum crusta Gallus domesticus (parching to brown), Olibanum, Myrrha, Pulvis Fumi Carbonisatus, promptly make described medicine behind the mix homogeneously.
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| CNA2005100470648A CN1772202A (en) | 2005-08-18 | 2005-08-18 | Gastrointestinal disease treating medicine and its production process |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306093B (en) * | 2008-06-06 | 2012-05-30 | 王丽城 | Decoction for treating esophagus cancer haematemesis |
| CN103478714A (en) * | 2013-09-22 | 2014-01-01 | 许春银 | Diet therapy composition for treating upper gastrointestinal hemorrhage |
-
2005
- 2005-08-18 CN CNA2005100470648A patent/CN1772202A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306093B (en) * | 2008-06-06 | 2012-05-30 | 王丽城 | Decoction for treating esophagus cancer haematemesis |
| CN103478714A (en) * | 2013-09-22 | 2014-01-01 | 许春银 | Diet therapy composition for treating upper gastrointestinal hemorrhage |
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