CN106577863A - Traditional Chinese medicine disinfectant and preparation method thereof - Google Patents
Traditional Chinese medicine disinfectant and preparation method thereof Download PDFInfo
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- CN106577863A CN106577863A CN201611077808.5A CN201611077808A CN106577863A CN 106577863 A CN106577863 A CN 106577863A CN 201611077808 A CN201611077808 A CN 201611077808A CN 106577863 A CN106577863 A CN 106577863A
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- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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Abstract
The invention discloses a traditional Chinese medicine disinfectant and a preparation method of the traditional Chinese medicine disinfectant, and belongs to the field of traditional Chinese medicines. The disinfectant is mainly prepared from the following raw materials by weight: 3-15 parts of radix bupleuri, 2-12 parts of mint, 3-10 parts of cortex phellodendri, 2-9 parts of hyperforin perforatum, 4-8 parts of areca-nut, 1-10 parts of radix ophiopogonis, 4-9 parts of herba houttuyniae, 3-11 parts of rhizoma coptidis, 4-11 parts of honeysuckle, 5-10 parts of liquorice, 2-8 parts of euphorbia kansui, 3-9 parts of cortex albiziae, 2-6 parts of radix ophiopogonis, 3-7 parts of fructus cnidii, 2-8 parts of Japanese cayratia herb, 5-8 parts of folium artemisiae argyi, and 300-600 parts of ethanol solution. The selected medicines of the traditional Chinese medicine disinfectant are compatible, the traditional Chinese medicine disinfectant has the advantages of high bactericidal ability and high stability, and in addition, the preparation method of the disinfectant is simple, the operation is convenient, and the traditional Chinese medicine disinfectant and the preparation method of the traditional Chinese medicine disinfectant are higher in application value.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Traditional Chinese medicine disinfectant and preparation method thereof.
Background technology
Disinfectant solution is used to kill the pathogenic microorganism on communication media, pathogenic microorganism is eliminated with outside human body, cuts off
The route of transmission of infectious disease, reaches the purpose of control infectious disease.The commonly used peracetic acid soln of hospital or chlorine-containing disinfection liquid spray
Spill sterilization.But, these disinfectant solution major parts are formed by the mutual proportioning of chemical composition, and life-time service is easy to make antibacterial
Resistance is produced, Disinfection Effect is reduced, and chemical composition more or less can all there are some to injure human body, life-time service, unavoidably
Can human body be caused to damage.
Traditional medicine of the Chinese medicine as China, with effect is strong, instant effect, lasting medicine, and no toxic and side effects.Cause
This, invents a kind of Traditional Chinese medicine disinfectant and is of great significance for hospital's tool that carries out disinfection.
The content of the invention
It is instant invention overcomes the shortcoming of above-mentioned technical problem, there is provided a kind of Traditional Chinese medicine disinfectant and preparation method thereof, selected
Medical material compatibility is suitable, strong with sterilizing ability, the strong advantage of stability.
To realize above-mentioned technical purpose, technical scheme is as follows：
A kind of Traditional Chinese medicine disinfectant, is mainly made up of the raw material of following weight portion：Radix Bupleuri 3-15 parts, Herba Menthae 2-12 parts, Cortex Phellodendri
3-10 parts, Herba Hyperici perforati 2-9 parts, Semen Arecae 4-8 parts, 1-10 parts Radix Ophiopogonis, Herba Houttuyniae 4-9 parts, Rhizoma Coptidis 3-11 parts, Flos Lonicerae 4-11
Part, Radix Glycyrrhizae 5-10 parts, Radix Kansui 2-8 parts, Cortex Albiziae 3-9 parts, 2-6 parts Radix Ophiopogonis, Fructus Cnidii 3-7 parts, Herba Cayatiae Japonicae 2-8 parts, Folium Artemisiae Argyi 5-8
Part and ethanol solution 300-600 parts.
Further, the Traditional Chinese medicine disinfectant is mainly made up of the raw material of following weight portion：Radix Bupleuri 4-12 parts, Herba Menthae 3-10
Part, Cortex Phellodendri 4-9 parts, Herba Hyperici perforati 3-8 parts, Semen Arecae 5-7 parts, 2-9 parts Radix Ophiopogonis, Herba Houttuyniae 5-8 parts, Rhizoma Coptidis 4-10 parts, Flos Lonicerae
5-10 parts, Radix Glycyrrhizae 6-9 parts, Radix Kansui 3-7 parts, Cortex Albiziae 4-8 parts, 3-5 parts Radix Ophiopogonis, Fructus Cnidii 4-6 parts, Herba Cayatiae Japonicae 3-7 parts, Folium Artemisiae Argyi
6-7 parts and ethanol solution 400-550 parts.
Further, the Traditional Chinese medicine disinfectant is mainly made up of the raw material of following weight portion：5 parts of Radix Bupleuri, 4 parts of Herba Menthae, Huang
5 parts of cypress, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, 6 parts of Flos Lonicerae, 7 parts of Radix Glycyrrhizae, Radix Kansui 4
450 parts of part, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution.
Further, the Traditional Chinese medicine disinfectant is mainly made up of the raw material of following weight portion：5 parts of Radix Bupleuri, 4 parts of Herba Menthae, Huang
5 parts of cypress, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, 6 parts of Flos Lonicerae, 7 parts of Radix Glycyrrhizae, Radix Kansui 4
500 parts of part, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution.
Further, the ethanol solution is the ethanol solution that volume fraction is 40-75%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 150-170 mesh thin
Powder, it is standby；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 7-15 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, add the distilled water of 200-500 parts, stirring
Uniform filtering, obtains liquor B, standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
The distilled water of 200-300 parts is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cold by cooler
But, coolant is collected, obtains final product the disinfectant solution.
Chinese crude drug details in the present invention is as follows：
Radix Bupleuri：Bitter in the mouth, cold nature；Return liver warp, gallbladder meridian.Reconciling superficies and interior, soothing the liver yang invigorating, for cold, fever, alternate attack of chill and fever,
Distending pain in the chest and hypochondrium, menoxenia, modern medicine study confirm that Radix Bupleuri has antiviral effect, and infected by influenza, Aerugo are false single
Born of the same parents bacterium, tulase have strong inhibitory action.
Herba Menthae, acrid in the mouth are cool.Enter lung meridian, Liver Channel.Can dispelling wind and heat pathogens, head clearing, sore-throat relieving rash, soothing the liver circulation of qi promoting.For outer
Sense wind heat, headache, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, sore scabies, urticaria, epidemic febrile disease from the beginning of, rubella itch, stagnation of QI due to depression of the liver,
Hypochondriac pain uncomfortable in chest.Pharmacological evaluation shows that Herba Menthae decoct is to diphtheria corynebacterium, escherichia coli, golden yellow staphylococcus, Shi Shi and Fu Shi dysentery
Bacillus, Bacillus proteuss, vibrio cholera, Bacillus typhi, bacillus pyocyaneus and tubercule bacillus etc. have obvious inhibitory action, to violet
The tinea funguses such as trichophyton, microsporon audouini and star-like slave card bacterium are also inhibited.
Cortex Phellodendri, bitter in the mouth are cold in nature.Kidney channel, bladder, large intestine channel.Can heat-clearing and toxic substances removing, purging intense heat eliminating dampness.Cure mainly acute bacterial dysentery
The inflammation such as disease, acute enteritises, acute icterohepatitises, urinary system infection.Burning hot wound, otitis media, acute conjunctivitiss are controlled in external
Deng.Pharmacological evaluation shows that Cortex Phellodendri has obvious inhibitory action to bacillus pyocyaneus, Bacillus proteuss etc..
Herba Hyperici perforati：Sweet in the mouth, slight bitter, are slightly cold.GUIXIN, lung, stomach.Can Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, relieving restlessness that clears away heart-fire.It is main
Control consumption of body fluid caused by febrile disease, vexed, thirsty, dry pharynx lung-heat, cough, pulmonary tuberculosis.Modern medicine study confirms that Herba Hyperici perforati decoct is to dysentery
Bacillus, Bacillus typhi, vibrio cholera, escherichia coli, Bacillus proteuss, bacillus pyocyaneus and staphylococcuses, streptococcus have suppression to make
With antimicrobial spectrum is also wider.
Semen Arecae, it is bitter in the mouth, pungent, it is warm in nature；Return stomach, large intestine channel；Killing insect and eliminating accumulation, sending down the abnormal ascending QI water-filling, preventing the attack (or recurrence) of malaria.For cestode, ascarid, Rhizoma Zingiberis Recens
Piece parasitosis, abdominal pain due to worm stagnation are stagnant to let out dysentery, tenesmus, edema tinea pedis, malaria.Modern medicine study confirms that Semen Arecae has anti-true
Bacterium, the effect of virus, infusion in vitro have a different degrees of inhibitory action to dermatophytess such as trichophytons, decoct and
Flooding agent infected by influenza has certain inhibitory action.
Radix Ophiopogonis, sweet in the mouth, slight bitter are slightly cold.GUIXIN, lung, stomach；Can Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, relieving restlessness that clears away heart-fire.Cure mainly heat
Sick impairment of body fluid, vexed, thirsty, dry pharynx lung-heat, cough, pulmonary tuberculosis.Modern medicine study confirms that Radix Ophiopogonis is to diphtheria corynebacterium, hemolytic
Streptococcus and staphylococcus aureuses have inhibitory action.
Herba Houttuyniae, acrid in the mouth, cold nature；Return lung Jing.Heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, wind syndrome of head, migratory arthralgia.《Do not record》Record：" support
Liver and gall, except cold and heat, kill tapeworm, treat wind syndrome of head, brain invasion by pathogenic cold, only excessive thirst, tonifying for the deficiency, Sheng Yinqi.”
Rhizoma Coptidis, bitter in the mouth are cold in nature, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.For retention of damp-heat in the interior, the intestines and stomach is damp and hot, vomit, rush down
Dysentery etc..Modern medicine study confirms that Rhizoma Coptidis are to staphylococcus aureuses, Hemolytic streptococcuss, streptococcus pneumoniae, the double balls of meningitiss
Bacterium, dysentery bacterium and anthrax bacillus etc. are respectively provided with inhibitory action.Decoct infected by influenza and hepatitis B virus etc. also have inhibitory action.
Flos Lonicerae, sweet in the mouth, slight bitter, delicate fragrance are pungent, tremble with fear.Return lung, stomach, the heart, large intestine channel.There are heat-clearing and toxic substances removing, the work(of dispelling wind and heat pathogens
Effect.The effective ingredient of Flos Lonicerae is chlorogenic acid, is a kind of antibiotic substance of natural wide spectrum, can play sterilization, effect of antiinflammatory.
Radix Glycyrrhizae, sweet in the mouth are put down, nontoxic.Enter spleen, stomach, lung meridian.Invigorating middle warmer and replenishing QI, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, tune
With all medicines.Main asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat
Swell and ache；Ulcerative carbuncle swells and ache；Infantile carbuncle；And medicine, alimentary toxicosis.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, expectorant of coughing
Many, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
Radix Kansui, bitter in the mouth are cold in nature；Returns spleen Jing, lung meridian, kidney channel, bladder warp, large intestine channel, small intestine meridian.Edema is cured mainly, ascites is stayed
Drink blocked-up chest, epilepsy are breathed with cough, sphincter disturbance.Modern medicine study confirms that Radix Kansui is to streptococcus pneumoniae escherichia coli, dysentery bacterium
And anthrax bacillus etc. are respectively provided with inhibitory action.
Cortex Albiziae, sweet in the mouth are mild-natured；Thoughts of returning home warp, Liver Channel.Which has resolving depression of calming the nerves, promoting blood circulation eliminating carbuncle, bactericidal antiphlogistic antineoplastic
Effect.
Radix Ophiopogonis, sweet in the mouth, slight bitter, cold nature.GUIXIN, lung, stomach.For dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, Tianjin
Wound is thirsty, Heat Diabetes, vexed insomnia, dry constipation of intestines, and modern medicine study confirms, has certain suppression to anthrax bacillus Radix Ophiopogonis
Effect.
Fructus Cnidii, acrid in the mouth, hardship are warm in nature.Return kidney channel.External treatment vulval eczema, married woman's pruritus vulvae, trichomonal vaginitis, eczema scabies
Tinea, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, impotence due to deficiency of the kidney, uterus cold infertile.Modern medicine study confirms that Fructus Cnidii has antibacterial and diseases prevention
Mechanism.
Herba Cayatiae Japonicae, also known as Herba Rubi blinii, cold in nature, bitter in the mouth, acid.Thoughts of returning home warp, Liver Channel, stomach.Modern pharmacological research shows its tool
There are antiviral, antiinflammatory, removing toxic substances, antibacterial.
Folium Artemisiae Argyi, it is warm in nature, bitter in the mouth, pungent.Return liver warp, spleen channel, kidney channel, make with antitussive, eliminating the phlegm, antibacterial, calm, shock etc.
With modern medicine study confirms, Folium Artemisiae Argyi has significantly to tubercule bacillus, staphylococcus aureuses, bacillus pyocyaneus and hepatitis B virus etc.
Killing action.
In summary, Traditional Chinese medicine disinfectant of the invention has the advantage that：
The disinfection of Chinese drug medicinal liquid of the present invention is formed by clinic tests and repeated verification configuration, meets the reason of Chinese medicine
By each raw material is mutually cooperateed with, and the advantage of each ingredient is fully played.Formula used by the Traditional Chinese medicine disinfectant is former
In material, with Radix Bupleuri, Herba Menthae, Cortex Phellodendri, Herba Hyperici perforati and Folium Artemisiae Argyi as monarch drug, the function with sterilizing is the Traditional Chinese medicine disinfectant
In to sterilize, anti-infective effective ingredient；With Semen Arecae, Radix Ophiopogonis, Herba Houttuyniae, Rhizoma Coptidis, Flos Lonicerae, Radix Glycyrrhizae, Radix Kansui, Cortex Albiziae,
Radix Ophiopogonis, Fructus Cnidii and Herba Cayatiae Japonicae be accessory drugss, the effect with antibacterial, antiinflammatory, increase monarch drug antiinflammatory effect；With ethanol solution it is
Adjuvant drug, Jing after alcohol solution dipping, the effective ingredient in medicine is leached out each component Chinese crude drug, and ethanol solution can
Penetrate in antibacterial body, make the protein coagulating of composition antibacterial, given full play to present invention sterilization, the drug effect of antiviral.This
Invention formulation composition has taken into full account the antibacterial spectrum signature of each composition so that the antimicrobial spectrum of each composition defines complementary action, disappears
The overall antimicrobial spectrum of venom is extensive, to antibacterial, funguses, actinomycetes, mycete, spore, mycoplasma, chlamydia, rickettsia etc.
All there is the killing effect of protrusion.Additionally, disinfectant solution of the present invention is obtained using pure natural raw material, in the environment using will not be to people
Body is damaged, will not toxic side effect, it is adaptable to used in the sterilizing of hospital.
Specific embodiment
The following examples can help those skilled in the art that the present invention is more completely understood, but cannot be with any
Mode limits the present invention.
Embodiment 1
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:3 parts of Radix Bupleuri, 2 parts of Herba Menthae, Huang
3 parts of cypress, 2 parts of Herba Hyperici perforati, 4 parts of Semen Arecae, 1 part of Radix Ophiopogonis, 4 parts of Herba Houttuyniae, 3 parts of Rhizoma Coptidis, 4 parts of Flos Lonicerae, 5 parts of Radix Glycyrrhizae, Radix Kansui 2
300 parts of part, 3 parts of Cortex Albiziae, 2 parts of Radix Ophiopogonis, 3 parts of Fructus Cnidii, 2 parts of Herba Cayatiae Japonicae, 5 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 40%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 150- mesh fine powders,
It is standby；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, alcohol solution dipping is added after 7 days, after boiling 2 hours, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 200 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
200 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
Embodiment 2
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:15 parts of Radix Bupleuri, 12 parts of Herba Menthae,
10 parts of Cortex Phellodendri, 9 parts of Herba Hyperici perforati, 8 parts of Semen Arecae, 10 parts of Radix Ophiopogonis, 9 parts of Herba Houttuyniae, 11 parts of Rhizoma Coptidis, 11 parts of Flos Lonicerae, 10 parts of Radix Glycyrrhizae,
600 parts of 8 parts of Radix Kansui, 9 parts of Cortex Albiziae, 6 parts of Radix Ophiopogonis, 7 parts of Fructus Cnidii, 8 parts of Herba Cayatiae Japonicae, 8 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 75%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 170 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 15 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 500 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
300 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
Embodiment 3
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:4 parts of Radix Bupleuri, 3 parts of Herba Menthae, Huang
4 parts of cypress, 3 parts of Herba Hyperici perforati, 5 parts of Semen Arecae, 2 parts of Radix Ophiopogonis, 5 parts of Herba Houttuyniae, 4 parts of Rhizoma Coptidis, 5 parts of Flos Lonicerae, 6 parts of Radix Glycyrrhizae, Radix Kansui 3
400 parts of part, 4 parts of Cortex Albiziae, 3 parts of Radix Ophiopogonis, 4 parts of Fructus Cnidii, 3 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 40%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 170 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 9 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 500 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
300 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
Embodiment 4
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:12 parts of Radix Bupleuri, 10 parts of Herba Menthae,
It is 9 parts of Cortex Phellodendri, 8 parts of Herba Hyperici perforati, 7 parts of Semen Arecae, 9 parts of Radix Ophiopogonis, 8 parts of Herba Houttuyniae, 10 parts of Rhizoma Coptidis, 10 parts of Flos Lonicerae, 9 parts of Radix Glycyrrhizae, sweet
Then 550 parts of 7 parts, 8 parts of Cortex Albiziae, 5 parts of Radix Ophiopogonis, 6 parts of Fructus Cnidii, 7 parts of Herba Cayatiae Japonicae, 7 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 75%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 150 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 10 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 200 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
200 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
Embodiment 5
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:5 parts of Radix Bupleuri, 4 parts of Herba Menthae, Huang
5 parts of cypress, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, 6 parts of Flos Lonicerae, 7 parts of Radix Glycyrrhizae, Radix Kansui 4
450 parts of part, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 55%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 160 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 8 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 300 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
250 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
Embodiment 6
A kind of Traditional Chinese medicine disinfectant, mainly makes (every part of 1g) by the raw material of following weight portion:5 parts of Radix Bupleuri, 4 parts of Herba Menthae, Huang
5 parts of cypress, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, 6 parts of Flos Lonicerae, 7 parts of Radix Glycyrrhizae, Radix Kansui 4
500 parts of part, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution.
Wherein, the ethanol solution is ethanol solution that volume fraction is 65%.
The present invention also provides a kind of preparation method of Traditional Chinese medicine disinfectant, and the method comprises the steps：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 150 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in into appearance
In device, add alcohol solution dipping after 15 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added 400 parts of distilled water, stir
Filter, obtain liquor B, it is standby；
(5) by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4),
280 parts of distilled water is added, after stirring and dissolving is uniform, boiling point is heated to, and is kept boiling, steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
For the disinfection effect of the Traditional Chinese medicine disinfectant of the checking present invention, antibacterial reality is carried out to the Traditional Chinese medicine disinfectant now
Test：
1st, experimental strain：Select two representative strains of hospital, escherichia coli and Pseudomonas aeruginosa.
2nd, bacterium culture medium：Nutrient agar and nutrient broth medium.
3rd, bacteriostatic experiment is divided into experimental group and matched group, and experimental group is the Traditional Chinese medicine disinfectant of the present invention, and matched group was selected
Fluoroacetic acid disinfectant solution.
4th, specific experiment step：
(1) preparation of bacterium solution：Above two strain is inoculated on two agar culture mediums respectively, 48 is cultivated at 35 DEG C
Hour, it is inoculated in two fresh nutrient broth mediums respectively from picking colonies typical in above-mentioned agar culture medium respectively,
At 35 DEG C, 15 hours are cultivated, it is standby；
(2) Traditional Chinese medicine disinfectant of the present invention and each 70ml of peracetic acid disinfectant are taken, is respectively placed in cut-back tank, to its point
Not Xi Shi 25 times, by above two dilution liquor be placed in two containers respectively, be placed under aseptic condition, it is standby；
(3) experimental strain by above-mentioned steps (1) through 15 hours of nutrient broth culture is divided with aseptic nutrient broth
Not Xi Shi 70 times, every kind of strain is sub-packed in two culture dishs, is respectively labeled as matched group and experimental group；
(4) dilute solution of two parts of Traditional Chinese medicine disinfectants of the invention obtained by above-mentioned steps (2) is respectively dropped into into experimental group
Culture dish, two parts of peracetic acid disinfectant dilute solutions are respectively dropped into matched group culture dish.
5th, laboratory observation measurement：
Above-mentioned experiment is observed, two groups of strains is observed and is measured strain revolution mark concrete outcome, and it is specific as follows
Table：
6th, after observation measurement is finished, above-mentioned culture dish is placed in standing under aseptic condition two days later, two groups of bacterium colonies are observed
Breeding situation：
Follow-up observation finds that matched group bacterium colony continues breeding, and experimental group bacterium colony is unchanged.
7th, experimental result：
In sum, Traditional Chinese medicine disinfectant of the present invention has excellent bactericidal effect, wherein, using the Chinese medicine of the present invention
Disinfectant solution carries out disinfection sterilization, and escherichia coli and Pseudomonas aeruginosa area of colony are respectively than being reduced using peracetic acid disinfectant
23.7% and 29.3%.The sterilization of matched group disinfectant solution is much larger than from the experimental group sterilizing ability of Traditional Chinese medicine disinfectant of the present invention
Ability, and all kinds of strains can be suppressed to continue breeding.It can be seen that the disinfection of Chinese drug formula of liquid of the present invention has certain originality, its
In mutually association increases the effect of sterilizing between each sufficient taste medicine.
Traditional Chinese medicine disinfectant of the present invention and preparation method thereof, can not only effectively sterilize, prevent pathogen transmission, and described
The preparation method of disinfectant solution is simple, easy to operate, with preferable using value.
Described above is the detailed description for preferably possible embodiments of the invention, but embodiment is not limited to this
Bright patent claim, the equal change completed under the technical spirit suggested by all present invention or modification change, all should belong to
In the covered the scope of the claims of the present invention.
Claims (6)
1. a kind of Traditional Chinese medicine disinfectant, it is characterised in that be mainly made up of the raw material of following weight portion：Radix Bupleuri 3-15 parts, Herba Menthae 2-
12 parts, Cortex Phellodendri 3-10 parts, Herba Hyperici perforati 2-9 parts, Semen Arecae 4-8 parts, 1-10 parts Radix Ophiopogonis, Herba Houttuyniae 4-9 parts, Rhizoma Coptidis 3-11 parts, gold
Flos Lonicerae 4-11 parts, Radix Glycyrrhizae 5-10 parts, Radix Kansui 2-8 parts, Cortex Albiziae 3-9 parts, 2-6 parts Radix Ophiopogonis, Fructus Cnidii 3-7 parts, Herba Cayatiae Japonicae 2-8
Part, Folium Artemisiae Argyi 5-8 parts and ethanol solution 300-600 parts.
2. a kind of Traditional Chinese medicine disinfectant according to claim 1, it is characterised in that the main raw material system by following weight portion
Into：Radix Bupleuri 4-12 parts, Herba Menthae 3-10 parts, Cortex Phellodendri 4-9 parts, Herba Hyperici perforati 3-8 parts, Semen Arecae 5-7 parts, 2-9 parts Radix Ophiopogonis, Herba Houttuyniae 5-
8 parts, Rhizoma Coptidis 4-10 parts, Flos Lonicerae 5-10 parts, Radix Glycyrrhizae 6-9 parts, Radix Kansui 3-7 parts, Cortex Albiziae 4-8 parts, 3-5 parts Radix Ophiopogonis, Fructus Cnidii
4-6 parts, Herba Cayatiae Japonicae 3-7 parts, Folium Artemisiae Argyi 6-7 parts and ethanol solution 400-550 parts.
3. a kind of Traditional Chinese medicine disinfectant according to claim 1, it is characterised in that the main raw material system by following weight portion
Into：5 parts of Radix Bupleuri, 4 parts of Herba Menthae, 5 parts of Cortex Phellodendri, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, gold silver
Spend 6 parts, 7 parts of Radix Glycyrrhizae, 4 parts of Radix Kansui, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution
450 parts.
4. a kind of Traditional Chinese medicine disinfectant according to claim 1, it is characterised in that the main raw material system by following weight portion
Into：5 parts of Radix Bupleuri, 4 parts of Herba Menthae, 5 parts of Cortex Phellodendri, 4 parts of Herba Hyperici perforati, 6 parts of Semen Arecae, 3 parts of Radix Ophiopogonis, 6 parts of Herba Houttuyniae, 5 parts of Rhizoma Coptidis, gold silver
Spend 6 parts, 7 parts of Radix Glycyrrhizae, 4 parts of Radix Kansui, 5 parts of Cortex Albiziae, 4 parts of Radix Ophiopogonis, 5 parts of Fructus Cnidii, 5 parts of Herba Cayatiae Japonicae, 6 parts of Folium Artemisiae Argyi and ethanol solution
500 parts.
5. a kind of Traditional Chinese medicine disinfectant according to claim 1, it is characterised in that the ethanol solution for volume fraction is
The ethanol solution of 40-75%.
6. the preparation method according to a kind of arbitrary described Traditional Chinese medicine disinfectant of claim 1-5, it is characterised in that including following step
Suddenly：
(1) above-mentioned raw materials are weighed by weight, it is standby；
(2) will be placed in mortar after Herba Menthae, Semen Arecae, Rhizoma Coptidis, Radix Kansui and Folium Artemisiae Argyi microwave drying and grind, cross 150-170 mesh fine powders, it is standby
With；
(3) Radix Bupleuri, Cortex Phellodendri, Herba Hyperici perforati, Radix Ophiopogonis, Herba Houttuyniae, Flos Lonicerae, Radix Glycyrrhizae, Fructus Cnidii and Herba Cayatiae Japonicae are placed in container,
Add alcohol solution dipping after 7-15 days, filter, obtain filtrate A, it is standby；
(4) Cortex Albiziae, Radix Ophiopogonis are placed in mortar and are ground with the micro- stir-fry of slow fire, added the distilled water of 200-500 parts, stir
Filter, obtain liquor B, it is standby；
(5), by the fine powder obtained by step (2), after mixing with the liquor B obtained by the filtrate A obtained by step (3), step (4), add
The distilled water of 200-300 parts, after stirring and dissolving is uniform, is heated to boiling point, and keeps boiling, and steam is cooled down by cooler, is received
Collection coolant, obtains final product the disinfectant solution.
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| CN107596417A (en) * | 2017-09-26 | 2018-01-19 | 北京健租宝科技有限公司 | Sterilization method and thimerosal of a kind of medicine equipment and preparation method thereof |
| CN108402110A (en) * | 2018-04-02 | 2018-08-17 | 重庆康元水处理设备有限责任公司 | A kind of disinfection agent prescription and preparation method thereof |
| CN108576081A (en) * | 2018-01-24 | 2018-09-28 | 合肥华盖生物科技有限公司 | A kind of medical equipment environment-friendly type Chinese medicine antiseptic and preparation method thereof |
| CN111280187A (en) * | 2020-03-11 | 2020-06-16 | 沧州佳和生物科技有限公司 | Compound traditional Chinese medicine disinfectant and preparation method thereof |
| CN111937911A (en) * | 2020-08-05 | 2020-11-17 | 亳州益智健康产业有限公司 | Traditional Chinese medicine disinfectant and preparation method thereof |
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| CN111937911A (en) * | 2020-08-05 | 2020-11-17 | 亳州益智健康产业有限公司 | Traditional Chinese medicine disinfectant and preparation method thereof |
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