CN106511910A

CN106511910A - Traditional Chinese medicine ointment for treating gout, and preparation method thereof

Info

Publication number: CN106511910A
Application number: CN201611257278.2A
Authority: CN
Inventors: 薛均来; 牛东铎; 薛铭铎; 赵树华; 万学文; 谢湘春; 方美善
Original assignee: Jilin University
Current assignee: Jilin University
Priority date: 2016-12-30
Filing date: 2016-12-30
Publication date: 2017-03-22

Abstract

The invention provides a traditional Chinese medicine ointment for treating gout, and a preparation method thereof. The traditional Chinese medicine ointment comprises traditional Chinese medicine extracts and ointment bases, wherein the Chinese medicine extracts are prepared from the following raw materials in parts by mass: 6-8 parts of rhizoma homalomenae, 1-3 parts of rhizoma curcumae longae, 4-5 parts of radix angelicae sinensis, 2-4 parts of erythrina indica lam, 2-3 parts of caulis sinomenii, 1-2 parts of radix stephaniae tetrandrae, 1-3 parts of acanthopanax trifoliatus(l.)merr, 2-3 parts of herba callicarpae pedunculatae, 2-3 parts of ramulus cinnamomi, 0-3 parts of radix scrophulariae, 3-6 parts of original radix glycyrrhizae, 2-3 parts of radix linderae, and 2-3 parts of rhizoma panacis majoris. The traditional Chinese medicine ointment is prepared by comprising the following steps: heating, standing, filtering, mixing and the like, the technology is simple, the prepared ointment has no toxic and side effects, is fast in effect, difficult to recur, has the efficacies of removing wind and dispelling cold, promoting blood circulation to arrest pain, and activating collaterals, achieves excellent treatment effects on the problems of redness, swelling, fever, pain and the like caused by gout, and is especially applicable to treatment of chronic gout.

Description

It is a kind of to treat Chinese medicinal ointment of gout and preparation method thereof

Technical field

The present invention relates to treat the technical field of Chinese medicine of gout, and in particular to a kind of Chinese medicinal ointment for treating gout and its Preparation method.

Background technology

Gout is a kind of as purine metabolic disturbance, blood uric acid increase, and causes uric acid crystal to be deposited on joint and joint week Enclose the caused characteristic arthritis of tissue.Gout can be divided into two big class of constitutional and Secondary cases according to cause of disease difference.Constitutional pain Wind refers on the basis of other diseases are excluded, due to caused by congenital purine metabolic disturbance and (or) uric acid excretion disorder；After Send out property gout to refer to and be secondary to underexcretion, myeloproliferative disease and chemotherapy of tumors institute caused by kidney disease or some drugses Uricopoiesis are caused to increase.In China, the sickness rate of gout is in rising trend in recent years, and China general population prevalence is about 1.14%, wherein TaiWan, China and In The Area of Qingdao is gout district occurred frequently, and more than 18 years old TaiWan, China aborigines prevalence is about 11.7%.The current kind of antigout drug is commonly used clinically seldom at present, clinical treatment is mainly with Colchicine, nonsteroidal anti-inflammatory Medicine, hormone, promotion urate excretion medicine (such as probenecid, sulfinpyrazone and Benzbromarone) and suppression uric acid synthetic drug (allopurinol) are It is main, but these medicines are all defective in treatment：Weak curative effect, large side effects, and cure the symptoms, not the disease, it is discontinued, becomes which The bottleneck of clinical practice.

The content of the invention

For above-mentioned problem, the present invention propose it is a kind of treat Chinese medicinal ointment of gout and preparation method thereof, by The steps such as heating, standing, filtration, mixing are obtained, and process is simple, obtained unguentum are without any side effects, instant effect, are difficult multiple Send out, there is expelling wind and cold, promoting blood circulation and stopping pain, tendons relaxing and meridians dredging, to pain wind-induced red, swollen, hot, pain the problems such as have it is excellent Therapeutic effect, be particularly well-suited to the treatment of chronic gout.

In order to realize above-mentioned purpose, the present invention adopts following technical scheme：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：It is Rhizoma Homalomenae 6-8 parts, Rhizoma Curcumae Longae 1-3 parts, Radix Angelicae Sinensis 4-5 parts, Cortex erythrinae 2-4 parts, Caulis Sinomenii 2-3 parts, anti- Own 1-2 parts, thorn Acanthopanan trifoliatus (L.) Merr. 1-3 parts, Folium Callicarpae Formosanae 2-3 parts, Ramulus Cinnamomi 2-3 parts, Radix Achyranthis 0-3 parts, Radix Glycyrrhizae 3-6 parts, Radix Linderae 2-3 parts, Pestalotia funera 2-3 parts.

Preferably, Chinese medicine extract is made up of following mass fraction：Rhizoma Homalomenae 7-8 parts, Rhizoma Curcumae Longae 2-3 parts, Radix Angelicae Sinensis 4.5-5 Part, Cortex erythrinae 3-4 parts, Caulis Sinomenii 2.5-3 parts, Radix Stephaniae Tetrandrae 1.6-2 parts, thorn Acanthopanan trifoliatus (L.) Merr. 2-3 parts, Folium Callicarpae Formosanae 2.5-3 parts, Ramulus Cinnamomi 2.8-3 Part, Radix Achyranthis 2-3 parts, Radix Glycyrrhizae 5-6 parts, Radix Linderae 2.5-3 parts, Pestalotia funera 2.5-3 parts.

Preferably, ointment base includes that mass ratio is 4:3 Oleum Terebinthinae and eucalyptus oil.

Preferably, the preparation method of the Chinese medicinal ointment of gout is treated, preparation process is as follows：

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 3-5 times of quality, first under the conditions of 95-105 DEG C in cleaning backward raw material Heating 5-15min, is then cooled to 75-90 DEG C of heating 40-60min；While hot by crushing Chinese medicine raw materials, treat which naturally cools to room It is slowly added to ethanol after temperature thereto, it is stirring while adding, stand 8-10h；40-60 DEG C of heating 20min is warming up to again, while hot mistake Filter, retains filtrate, and adds the ethanol water of 2-3 times of quality in filtering residue, carries out post bake, and filtered while hot retains filter Liquid；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.15-1.17g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

By Chinese medicine extract and appropriate ointment base, water heating blending, the Chinese medicinal ointment for the treatment of gout after stirring, is obtained final product Agent.

Preferably, step 1) in the addition of ethanol be 1-1.2 times of clear water addition.

Preferably, step 1) in ethanol water alcohol content be 40%.

Preferably, step 1) in post bake be specially 50 DEG C of heating-up temperature, heat time heating time 35-45min.

Due to using above-mentioned technical scheme, the invention has the beneficial effects as follows：The present invention is with Rhizoma Homalomenae, Caulis Sinomenii, pittosporum tobira Based on skin expelling wind and dampness, relaxing muscles and tendons and activating QI and blood in the collateral, it is aided with heat-clearing and toxic substances removing, hemostasis promoting blood circulation, the Pestalotia funera of anti-inflammatory and antalgic, Folium Callicarpae Formosanae, thorn Acanthopanan trifoliatus (L.) Merr. Deng medicine, Caulis Sinomenii, Cortex erythrinae coordinate Radix Angelicae Sinensis, Radix Stephaniae Tetrandrae reducing swelling and alleviating pain, promoting blood circulation qi-restoratives, Rhizoma Curcumae Longae, Ramulus Cinnamomi blood-activating and qi-promoting, only stimulate the menstrual flow Bitterly, expelling cold and relieving exterior syndrome, Radix Linderae warming kidney for dispelling cold, antibacterial spasmolytic, Radix Glycyrrhizae mediation property of medicine, through the overall situation.

The present invention by heating, stand, filter, the step such as mixing is obtained, process is simple, prepare it is easy, obtained unguentum without Any toxic and side effects, instant effect are difficult recurrence, have functions that expelling wind and cold, promoting blood circulation and stopping pain, tendons relaxing and meridians dredging, gout is caused Red, swollen, hot, pain the problems such as there is excellent therapeutic effect, be particularly well-suited to the treatment of chronic gout.

In the present invention, ointment base is, using existing conventional technology of preparing, in addition to including Oleum Terebinthinae and eucalyptus oil, also to wrap Conventional substrate and additive, such as cosolvent, emulsifying agent, thickening agent, preservative, antioxidant, penetration enhancer etc. is included, substrate is Greasing base, such as vaseline, lanoline, liquid paraffin, Cera Flava etc..

Specific embodiment

For making purpose, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention, Technical scheme in the embodiment of the present invention is clearly and completely described.Based on embodiments of the invention, the common skill in this area The every other embodiment obtained under the premise of creative work is not made by art personnel, belongs to the model of present invention protection Enclose.

Embodiment 1：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：6.7 parts of Rhizoma Homalomenae, 2 parts of Rhizoma Curcumae Longae, 4 parts of Radix Angelicae Sinensis, 3.5 parts of Cortex erythrinae, 2.5 parts of Caulis Sinomenii, Radix Stephaniae Tetrandrae 1.3 Part, 2 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2.2 parts of Folium Callicarpae Formosanae, 2.5 parts of Ramulus Cinnamomi, 1.6 parts of Radix Achyranthis, 5 parts of Radix Glycyrrhizae, 2.4 parts of the Radix Linderae, Pestalotia funera 2.5 Part.

The preparation method of the Chinese medicinal ointment for the treatment of gout, preparation process are as follows：

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 3 times of quality, first heat under the conditions of 98 DEG C in cleaning backward raw material 5min, is then cooled to 75 DEG C of heating 55min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1.1 times of clear water quality, it is stirring while adding, stand 8h；Be warming up to again 45 DEG C heating 20min, filtered while hot, Retain filtrate, and in filtering residue add 2 times of quality 40% ethanol water, heat 40min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.15g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 2：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：7.2 parts of Rhizoma Homalomenae, 1.5 parts of Rhizoma Curcumae Longae, 4.3 parts of Radix Angelicae Sinensis, 3.8 parts of Cortex erythrinae, 2.8 parts of Caulis Sinomenii, Radix Stephaniae Tetrandrae 1.4 parts, thorn 1.8 parts of Acanthopanan trifoliatus (L.) Merr., 2.3 parts of Folium Callicarpae Formosanae, 2.4 parts of Ramulus Cinnamomi, 1 part of Radix Achyranthis, 4 parts of Radix Glycyrrhizae, 2.5 parts of the Radix Linderae, Pestalotia funera 2.3 part.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 4 times of quality, first heat under the conditions of 100 DEG C in cleaning backward raw material 10min, is then cooled to 80 DEG C of heating 50min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1 times of clear water quality, it is stirring while adding, stand 8.5h；60 DEG C of heating 20min are warming up to again, and filtered while hot is protected Reserved filtrate, and in filtering residue add 3 times of quality 40% ethanol water, heat 45min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.16g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 3：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：7.8 parts of Rhizoma Homalomenae, 1.2 parts of Rhizoma Curcumae Longae, 4.5 parts of Radix Angelicae Sinensis, 4 parts of Cortex erythrinae, 3 parts of Caulis Sinomenii, 1 part of Radix Stephaniae Tetrandrae, 2.5 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2.8 parts of Folium Callicarpae Formosanae, 2.6 parts of Ramulus Cinnamomi, 2 parts of Radix Achyranthis, 4.5 parts of Radix Glycyrrhizae, 2 parts of the Radix Linderae, 2 parts of Pestalotia funera.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 4 times of quality, first heat under the conditions of 105 DEG C in cleaning backward raw material 15min, is then cooled to 80 DEG C of heating 60min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1 times of clear water quality, it is stirring while adding, stand 9h；50 DEG C of heating 20min are warming up to again, and filtered while hot retains Filtrate, and add in filtering residue 3 times of quality 40% ethanol water, heat 40min under the conditions of 50 DEG C, filtered while hot, Retain filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.16g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 4：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：7.5 parts of Rhizoma Homalomenae, 2.2 parts of Rhizoma Curcumae Longae, 5 parts of Radix Angelicae Sinensis, 2.5 parts of Cortex erythrinae, 2 parts of Caulis Sinomenii, Radix Stephaniae Tetrandrae 1.5 Part, 3 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2.5 parts of Folium Callicarpae Formosanae, 2.8 parts of Ramulus Cinnamomi, 0.5 part of Radix Achyranthis, 6 parts of Radix Glycyrrhizae, 2 parts of the Radix Linderae, 3 parts of Pestalotia funera.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 5 times of quality, first heat under the conditions of 100 DEG C in cleaning backward raw material 15min, is then cooled to 90 DEG C of heating 45min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1.2 times of clear water quality, it is stirring while adding, stand 9h；Be warming up to again 50 DEG C heating 20min, filtered while hot, Retain filtrate, and in filtering residue add 3 times of quality 40% ethanol water, heat 40min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.17g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 5：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：6 parts of Rhizoma Homalomenae, 2.5 parts of Rhizoma Curcumae Longae, 4.4 parts of Radix Angelicae Sinensis, 2 parts of Cortex erythrinae, 2.5 parts of Caulis Sinomenii, 2 parts of Radix Stephaniae Tetrandrae, 1 part of Acanthopanan trifoliatus (L.) Merr. of thorn, 3 parts of Folium Callicarpae Formosanae, 3 parts of Ramulus Cinnamomi, 3 parts of Radix Achyranthis, 5 parts of Radix Glycyrrhizae, 2.4 parts of the Radix Linderae, 3 parts of Pestalotia funera.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 5 times of quality, first heat under the conditions of 102 DEG C in cleaning backward raw material 10min, is then cooled to 90 DEG C of heating 50min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1.2 times of clear water quality, it is stirring while adding, stand 10h；Be warming up to again 40 DEG C heating 20min, filtered while hot, Retain filtrate, and in filtering residue add 2 times of quality 40% ethanol water, heat 35min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.17g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 6：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：8 parts of Rhizoma Homalomenae, 3 parts of Rhizoma Curcumae Longae, 4.8 parts of Radix Angelicae Sinensis, 3 parts of Cortex erythrinae, 2.2 parts of Caulis Sinomenii, 1.8 parts of Radix Stephaniae Tetrandrae, 1.5 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2.5 parts of Folium Callicarpae Formosanae, 2.8 parts of Ramulus Cinnamomi, 0 part of Radix Achyranthis, 4 parts of Radix Glycyrrhizae, 2.8 parts of the Radix Linderae, 2.5 parts of Pestalotia funera.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 5 times of quality, first heat under the conditions of 95 DEG C in cleaning backward raw material 8min, is then cooled to 85 DEG C of heating 50min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1 times of clear water quality, it is stirring while adding, stand 10h；60 DEG C of heating 20min are warming up to again, and filtered while hot is protected Reserved filtrate, and in filtering residue add 2 times of quality 40% ethanol water, heat 35min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.15g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 7：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：7 parts of Rhizoma Homalomenae, 2 parts of Rhizoma Curcumae Longae, 4.6 parts of Radix Angelicae Sinensis, 2.2 parts of Cortex erythrinae, 2.6 parts of Caulis Sinomenii, Radix Stephaniae Tetrandrae 1.6 Part, 2.4 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2 parts of Folium Callicarpae Formosanae, 2.6 parts of Ramulus Cinnamomi, 2.5 parts of Radix Achyranthis, 3.5 parts of Radix Glycyrrhizae, 3 parts of the Radix Linderae, Pestalotia funera 2.7 Part.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 3 times of quality, first heat under the conditions of 100 DEG C in cleaning backward raw material 5min, is then cooled to 75 DEG C of heating 60min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1.1 times of clear water quality, it is stirring while adding, stand 9.5h；45 DEG C of heating 20min are warming up to again, while hot mistake Filter, retain filtrate, and in filtering residue add 2 times of quality 40% ethanol water, heat 40min under the conditions of 50 DEG C, take advantage of Heat filtering, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.15g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Embodiment 8：

A kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, wherein Chinese medicine extract by Following mass fraction is made：6.5 parts of Rhizoma Homalomenae, 1 part of Rhizoma Curcumae Longae, 4 parts of Radix Angelicae Sinensis, 4 parts of Cortex erythrinae, 2.8 parts of Caulis Sinomenii, 1.5 parts of Radix Stephaniae Tetrandrae, 2 parts of Acanthopanan trifoliatus (L.) Merr. of thorn, 2.7 parts of Folium Callicarpae Formosanae, 2 parts of Ramulus Cinnamomi, 1.2 parts of Radix Achyranthis, 3 parts of Radix Glycyrrhizae, 2.6 parts of the Radix Linderae, 2.6 parts of Pestalotia funera.

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 4 times of quality, first heat under the conditions of 95 DEG C in cleaning backward raw material 12min, is then cooled to 85 DEG C of heating 50min；While hot by crushing Chinese medicine raw materials, delay after which naturally cools to room temperature thereto The slow ethanol for adding 1.1 times of clear water quality, it is stirring while adding, stand 10h；Be warming up to again 55 DEG C heating 20min, filtered while hot, Retain filtrate, and in filtering residue add 3 times of quality 40% ethanol water, heat 45min under the conditions of 50 DEG C, while hot mistake Filter, retains filtrate；Merge filtrate twice, reclaim ethanol, and be concentrated into 1.16g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

Clinical effectiveness case：

1) treat patient

2014-2016 treats patient 73, wherein male patient 56,48 years old mean age, average illness year history altogether 4.5 year；Female patient 17,44 years old mean age, average illness year history 3.2 years.

2) Therapeutic Method

Chinese medicinal ointment prepared by Example 1, it is daily to be respectively once applied in swollen joint sore spot sooner or later, first use before specifically smearing Handss are gently rubbed to heating slightly, are repasted with Chinese medicinal ointment of the present invention.

3) diagnostic criteria

Referring in particular to《Chinese medical disease Standardization of diagnosis and curative effect》.

4) treat standard

Cure：Redness and swelling of joints, pain disappear, and blood uric acid is normal, and 3 months after being discontinued in without rebound phenomenon.

Effectively：Redness and swelling of joints, pain substantially mitigate, and blood uric acid declines.

It is invalid：, without substantially mitigation, blood uric acid is unchanged for redness and swelling of joints, pain.

5) therapeutic outcome

After above-mentioned Therapeutic Method 15 days, male patient's effective percentage is 91%, female patient effective percentage 88%, 27 days Afterwards, man, female patient effective percentage are up to 100%, continuous to be discontinued using after 45-70 days, tracking observation, and man, female patient are without multiple It was found that as.

6) case introduction

Case 1：Patient's Mr. Wang, Taizhou of Zhejiang people are 45 years old, ill 1 year, the prolonged and repeated red and swollen, pain of left foot toe joint, Attempted various antiinflammatory, analgesic invalid, Chinese medicinal ointment of the present invention was used in November, 2013, red and swollen regression, pain after 8 days Significantly mitigate, pain disappears after 25 days, blood uric acid tends to normal, be discontinued after continuously smearing 40 days, 3 after tracking and monitoring drug withdrawal Month, without rebound phenomenon.Later stage follow-up, without recurrence.

Case 2：Patient Zhao Xiansheng, Zhanjiang people are 62 years old, ill 5 years, and the long-term hurt like hell of both legs knee joint is red and swollen Substantially, scorching hot convulsion is often felt like, limitation of activity uses Chinese medicinal ointment of the present invention in March, 2014, red and swollen after 15 days to disappear, Pain mitigates, and after 30 days, joint mobility strengthens, and after 45 days, without obvious pain, after 50 days, blood uric acid tends to normal, Can normal activity, after 65 days be discontinued, tracking and monitoring be discontinued after 3 months, without rebound phenomenon.Later stage follow-up, without recurrence.

Above example only to illustrate technical scheme, rather than a limitation；Although with reference to the foregoing embodiments The present invention has been described in detail, it will be understood by those within the art that：Which still can be to aforementioned each enforcement Technical scheme described in example is modified, or carries out equivalent to which part technical characteristic；And these modification or Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.

Claims

1. a kind of Chinese medicinal ointment for treating gout, which is made up of Chinese medicine extract and ointment base, it is characterised in that the Chinese medicine Extract is made up of following mass fraction：Rhizoma Homalomenae 6-8 parts, Rhizoma Curcumae Longae 1-3 parts, Radix Angelicae Sinensis 4-5 parts, Cortex erythrinae 2-4 parts, Caulis Sinomenii 2- 3 parts, Radix Stephaniae Tetrandrae 1-2 parts, thorn Acanthopanan trifoliatus (L.) Merr. 1-3 parts, Folium Callicarpae Formosanae 2-3 parts, Ramulus Cinnamomi 2-3 parts, Radix Achyranthis 0-3 parts, Radix Glycyrrhizae 3-6 parts, the Radix Linderae 2-3 parts, Pestalotia funera 2-3 parts.

2. the Chinese medicinal ointment for the treatment of gout according to claim 1, which is made up of Chinese medicine extract and ointment base, and which is special Levy and be, the Chinese medicine extract is made up of following mass fraction：Rhizoma Homalomenae 7-8 parts, Rhizoma Curcumae Longae 2-3 parts, Radix Angelicae Sinensis 4.5-5 parts, sea Cortex paulowniae 3-4 parts, Caulis Sinomenii 2.5-3 parts, Radix Stephaniae Tetrandrae 1.6-2 parts, thorn Acanthopanan trifoliatus (L.) Merr. 2-3 parts, Folium Callicarpae Formosanae 2.5-3 parts, Ramulus Cinnamomi 2.8-3 parts, soil Radix Achyranthis Bidentatae 2-3 parts, Radix Glycyrrhizae 5-6 parts, Radix Linderae 2.5-3 parts, Pestalotia funera 2.5-3 parts.

3. it is according to claim 1 and 2 treatment gout Chinese medicinal ointment, it is characterised in that：The ointment base includes matter Amount is than being 4:3 Oleum Terebinthinae and eucalyptus oil.

4. it is according to claim 1 and 2 treatment gout Chinese medicinal ointment preparation method, it is characterised in that preparation process It is as follows：

1) preparation of Chinese medicine extract

Powder weighs raw material by weight, adds the clear water of 3-5 times of quality, first heat under the conditions of 95-105 DEG C in cleaning backward raw material 5-15min, is then cooled to 75-90 DEG C of heating 40-60min；While hot by crushing Chinese medicine raw materials, after which naturally cools to room temperature Ethanol is slowly added to thereto, it is stirring while adding, stand 8-10h；40-60 DEG C of heating 20min is warming up to again, and filtered while hot is protected Reserved filtrate, and the ethanol water of 2-3 times of quality is added in filtering residue, post bake is carried out, filtered while hot retains filtrate；Close And filtrate twice, ethanol is reclaimed, and is concentrated into 1.15-1.17g/ml, obtain final product Chinese medicine extract；

2) preparation of Chinese medicinal ointment

By Chinese medicine extract and appropriate ointment base, water heating blending, the Chinese medicinal ointment for the treatment of gout after stirring, is obtained final product.

5. it is according to claim 4 treatment gout Chinese medicinal ointment preparation method, it is characterised in that：Step 1) in ethanol Addition be 1-1.2 times of clear water addition.

6. it is according to claim 4 treatment gout Chinese medicinal ointment preparation method, it is characterised in that：Step 1) in ethanol In aqueous solution, alcohol content is 40%.

7. it is according to claim 4 treatment gout Chinese medicinal ointment preparation method, it is characterised in that：Step 1) in it is secondary Heating be specially 50 DEG C of heating-up temperature, heat time heating time 35-45min.