CN106511845A - 养心脾阿胶组合物及其制备方法 - Google Patents
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- CN106511845A CN106511845A CN201710024771.8A CN201710024771A CN106511845A CN 106511845 A CN106511845 A CN 106511845A CN 201710024771 A CN201710024771 A CN 201710024771A CN 106511845 A CN106511845 A CN 106511845A
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Abstract
养心脾阿胶组合物及其制备方法,属于保健食品技术领域。由以下重量份的原料组成:百合5~10份、茯苓5~10份、莲子5~10份、炒麦芽17~22份、小麦28~32份、牡蛎5~10份、栀子9~12份、酸枣仁9~12份、枸杞9~12份、大枣5~15份、龙眼肉5~15份、黑芝麻10~20份、核桃10~20份、阿胶10~70份,黄酒10~70份。该养心脾阿胶组合物对于心脾两虚引起的心烦、失眠、大便稀溏、头晕、面色萎黄、食欲不振、心慌、多汗、月经不调、腰膝酸软均有较好的疗效,见效快,且无副作用。
Description
技术领域
养心脾阿胶组合物及其制备方法,属于保健食品技术领域。
背景技术
心脾两虚是心血不足,脾气虚弱所致的病症。多由饮食不节,劳倦伤脾,或久病失调及慢性出血,或思虑过度暗耗阴血等引起。心血不足,脾气虚弱所致,临床以心悸失眠,纳差腹胀,便溏出血为主要表现的症。心脾两虚症,广义包括心脾气虚,心脾阴虚,心脾气阴两虚等几种类型。由于心主血,脾主运化,所以临床的心脾两虚症以心血不足,脾气虚弱者为常见。本证常见于有心悸怔忡、失眠多梦、食少、大便稀溏、倦怠乏力、或见崩漏、便血、皮下出血、舌淡、脉细弱、虚劳、健忘、眩晕、血症,以及西医的神经官能症、贫血、心律失常、心肌炎等疾病。心脾两虚证除具备血液的病变(血虚、出血)外,尚有消化功能失职的表现,缘由脾气虚所致。若脾气虚损,制水无权,水湿泛滥,聚湿成痰,则形成痰饮、水气,蒙蔽心窍或上凌于心的病理转归,表现为神志不清,喉中痰鸣的癫症、痫证或心悸、水肿症。
申请人在研究中发现:心脾两虚,是困扰人们的常见疾病,以上病症给患者的工作和生活带来较大的痛苦。现有技术中多采用药物治疗,其治疗周期较长、治疗费用昂贵、药物多存在毒副作用,且治愈率和有效率较低,病症难以根治。
发明内容
本发明要解决的技术问题是:克服现有技术的不足,提供养心脾阿胶组合物及其制备方法,该养心脾阿胶组合物对于心脾两虚引起的心烦、失眠、大便稀溏、头晕、面色萎黄、食欲不振、心慌、多汗、月经不调、腰膝酸软均有较好的疗效,见效快,且无副作用。
本发明解决其技术问题所采用的技术方案是:该养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合5~10份、茯苓5~10份、莲子5~10份、炒麦芽17~22份、小麦28~32份、牡蛎5~10份、栀子9~12份、酸枣仁9~12份、枸杞9~12份、大枣5~15份、龙眼肉5~15份、黑芝麻10~20份、核桃10~20份、阿胶10~70份,黄酒10~70份。
该养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合6~8份、茯苓7~9份、莲子7~9份、炒麦芽19~21份、小麦29~31份、牡蛎6~8份、栀子10~11份、酸枣仁10~11份、枸杞7~9份、大枣8~10份、龙眼肉8~10份、黑芝麻14~18份、核桃12~15份、阿胶15~50份,黄酒15~100份。
该养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合7份、茯苓8份、莲子8份、炒麦芽20份、小麦30份、牡蛎7份、栀子10.5份、酸枣仁11份、枸杞8份、大枣9~9.5份、龙眼肉9~9.5份、黑芝麻16~17份、核桃13~14份、阿胶20~40份,黄酒40~120份。
所述的阿胶和黄酒按照质量比1:1添加。
该养心脾阿胶组合物的制备方法,其特征在于,制备成阿胶糕,包括以下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2~3次,每次2~3h,过滤合并提取液,浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒浸泡溶解,获得混合液;
3)将黑芝麻和核桃在烘烤至酥脆;将混合液煮沸、熬制呈黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,即得。
所述的烘烤至酥脆的具体操作为:将黑芝麻和核桃分别在80~100℃下烘烤至含水率低于7%。
所述的熬制呈黏稠膏体的具体操作为:将混合液加热至100~120℃,至混合液含水率15~25%时停止加热,获得黏稠膏体。
或者,该养心脾阿胶组合物的制备方法,其特征在于,制备成阿胶冲剂,包括以下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2~3次,每次2~3h,过滤合并提取液,浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,倒入黄酒浸泡溶解,浓缩、干燥得阿胶粉;
3)按重量份配比称取大枣、龙眼肉、黑芝麻和核桃分别脱水、粉碎过100~500目筛,混合均匀,得细粉;将浸膏粉、阿胶粉和细粉混合,干燥、过100~500目筛、灭菌得阿胶冲剂。
步骤3)所述的脱水的具体操作为:在80~100℃下烘烤至含水率低于7%,或者,采用真空冷冻干燥至含水率低于7%。
申请人对于本发明的说明如下:
百合,味甘、微苦、微寒。归心、肺经。功能主治:养阴润肺;清心安神。主阴虚久嗽;痰中带血;热病后期;余热未清,或情志不遂所致的虚烦惊悸、失眠多梦、精神恍惚;痈肿;湿疮。药理作用:镇咳祛痰作用、镇静作用、滋阴润肺作用、强壮作用、抗癌作用。
莲子,味甘、涩,性平。归脾、肾、心经。功效主治:补脾止泻,止带,益肾涩精,养心安神。用于脾虚泄泻,带下,遗精,心悸失眠。本发明中所用莲子为去除莲芯后的莲子,莲芯过于苦涩,不宜作为口服阿胶制品的添加剂。
茯苓,味甘、淡,性平。归心、肺、脾、肾经。利水渗湿,健脾,宁心用于水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠。药理作用:利尿作用;抗菌作用;对消化系统的影响。
炒麦芽,味甘,平。归脾、胃经。功能主治:行气消食,回乳,健脾开胃,退乳消胀。用于食积不消,脘腹胀痛,脾虚食少,乳汁郁积,乳房胀痛,妇女断乳。
小麦,味甘;性凉。归心;脾;肾经功能主治:养心;益肾;除热;止渴。主脏躁;烦热;消渴;泄利;痈肿;外伤出血;烫伤。药理作用:镇痛及抗病毒作用,从小麦中提取的脂多糖静脉注射或灌胃,均可抑制醋酸引起的小鼠扭体反应,有显着的镇痛作用,脂多糖可激活巨噬细胞而发挥抗病毒作用,临床上对各种疱疹患者有效。
牡蛎,味咸湿,性凉。入肝、肾经。功能主治:敛阴,潜阳,止汗,涩精,化痰,软坚。治惊痫,眩晕,自汗,盗汗,遗精,淋浊,崩漏,带下,瘰疬,瘿瘤。用于惊悸失眠,眩晕耳鸣,瘰疠痰核,瘕痞块,自汗盗汗,遗精崩带,胃痛泛酸。煅牡蛎收敛固涩。用于自汗盗汗,遗精崩带,胃痛吞酸。
栀子,苦;寒。归心;肝;肺;胃;三焦经。功能主治:泻火除烦;清热利湿;凉血解毒。主热病心烦;肝火目赤;头痛;湿热黄疳;淋症;叶血衄血;血痢尿血;口舌生疮;疮疡肿毒;扭伤肿痛。药理作用:利胆作用;镇静、降压作用;抗微生物作用。
酸枣仁,性味甘,平。入心、脾、肝、胆经。功能主治:养肝,宁心,安神,敛汗。治虚烦不眠,惊悸怔忡,烦渴,虚汗。药理作用:镇静、催眠作用;镇痛、抗惊厥、降温作用;对心血管系统的影响;对烧伤的影响。
龙眼肉,甘,温。归心、脾经。功能主治:补益心脾,养血安神。用于气血不足,心悸怔忡,健忘失眠,血虚萎黄。
枸杞,甘,平。归肝、肾经。功能主治:滋补肝肾,益精明目。用于虚劳精亏,腰膝酸痛,眩晕耳鸣,内热消渴,血虚萎黄,目昏不明。枸杞具有抗脂肪肝的作用、拟胆碱样作用。
黑芝麻,为胡麻科芝麻的黑色种子,含有大量的脂肪和蛋白质,还含有糖类、维生素A、维生素E、卵磷脂、微量元素(钙、铁、铬)。有健胃、保肝、促进红细胞生长的作用,同时可以增加体内黑色素,有利于头发生长。
核桃,性味甘,温。归肾、肺、大肠经。功能主治:补肾,温肺,润肠。用于腰膝酸软,阳痿遗精,虚寒喘嗽,大便秘结。
大枣,甘平,无毒,主心腹邪气,安中,养脾气,平胃气,通九窍,助十二经,补少气,少津液、身中不足,大惊,四肢重,和百药,久服轻身延年,能令出汗、抗过敏、除腥臭、怪味、宁心安神、益智健脑、增强食欲。对防治心血管疾病、急慢性肝炎、肝硬化、贫血、过敏性紫癜有较好的疗效。优选的,本发明中所用的大枣为去核去皮后的大枣(即枣肉部分),大枣的枣核和枣皮即使经开水冲泡或沸煮碎后依然硬度较高,患者吞咽时口感粗粝,加入后影响患者服用的积极性。
阿胶,味甘,性平。归肺、肝、肾经。功能主治:补血滋阴,润燥,止血。用于血虚萎黄,眩晕心悸,肌痿无力,心烦不眠,虚风内动,肺燥咳嗽,劳嗽咯血,吐血尿血,便血崩漏,妊娠胎漏。优选的,所述的阿胶为两年陈胶、三年陈胶或四年陈胶。优选的,阿胶为山东东阿阿胶股份有限公司生产的阿胶。三年陈胶的意思是生产日期为三年前的阿胶,例如16年1月使用阿胶作为原料时,需使用生产日期为12年1月至14年1月期间的阿胶。
黄酒,味苦、辛,性温,入足厥阴肝、足少阳胆经。黄酒辛温升发,温血脉而消寒涩,阳虚火败,营卫冷滞者宜之,尤宜女子,故胎产诸方,多用黄酒。
优选的,所诉的枸杞为黑枸杞,所述的小麦为黑小麦。黑小麦和黑枸杞中富含花青素,能够清除人体内的自由基、提高免疫力,延缓衰老,消炎抗菌的功效。
与现有技术相比,本发明的养心脾阿胶组合物及其制备方法所具有的有益效果是:
1、本发明的养心脾阿胶组合物对于心脾两虚引起的心烦、失眠、大便稀溏、头晕、面色萎黄、食欲不振、心慌、多汗、月经不调、腰膝酸软均有较好的疗效,见效快,且无副作用。申请人设计了本发明的养心脾阿胶组合物,该养心脾阿胶组合物以口服的方式服用,食疗兼顾,达到了治疗目的,并且长期服用无毒副作用。经申请人临床统计,以1个月为一个疗程,服用至2~3个疗程(2~3个月)显效,服用至6个疗程(6个月)治愈,对于心脾两虚引起的心烦、失眠、大便稀溏、头晕、面色萎黄、食欲不振、心慌、多汗、月经不调、腰膝酸软治愈率达到95~100%,有效率达到100%。
2、本发明的养心脾阿胶组合物的制备方法简便易行,服用方便。申请人设计了两种不同的制备方法,将本发明组合物制成阿胶糕或阿胶冲剂,既便于口服食用,其制备方法又提高了药效。养心脾阿胶组合物制成的阿胶糕,采用加水90~95℃热回流提取的方式对百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞进行提取, 获得富含药效成分的浸膏粉,既减小了药物的体积,又浓缩的药效,同时改善了阿胶组合物的食用口感。
具体实施方式
实施例1~6是本发明的养心脾阿胶组合物及其制备方法的具体实施例,其中实施例1为最佳实施方式。实施例1~6所用的阿胶为山东东阿阿胶股份有限公司生产的三年陈胶。实施例中所用黑枸杞为青海产,所用红枸杞为宁夏产。所用黄酒为即墨黄酒厂生产的焦香型即墨黄酒。
实施例1
由以下重量份的原料制成:百合7份、茯苓8份、莲子8份、炒麦芽20份、小麦30份、牡蛎7份、栀子10.5份、酸枣仁11份、枸杞8份、大枣9份、龙眼肉9份、黑芝麻17份、核桃13、阿胶25份,黄酒25份;所用枸杞为黑枸杞,所用小麦为黑小麦;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取3次,每次2h,过滤合并提取液,减压浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒在5~25℃浸泡溶解,获得混合液;
3)将黑芝麻和核桃在分别在80~90℃下烘烤至含水率低于7%;将混合液煮沸、100~110℃加热,至混合液含水率15~25%时停止加热,获得黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,得阿胶糕。
实施例2
由以下重量份的原料制成:百合8份、茯苓7份、莲子9份、炒麦芽19份、小麦31份、牡蛎6份、栀子11份、酸枣仁10份、枸杞9份、大枣8份、龙眼肉10份、黑芝麻14份、核桃15份、阿胶15份,黄酒15份;所用枸杞为黑枸杞,所用小麦为黑小麦;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2次,每次3h,过滤合并提取液,减压浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒在5~25℃浸泡溶解,获得混合液;
3)将黑芝麻和核桃在分别在80~90℃下烘烤至含水率低于7%;将混合液煮沸、100~110℃加热,至混合液含水率15~25%时停止加热,获得黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,得阿胶糕。
实施例3
由以下重量份的原料制成:百合6份、茯苓9份、莲子7份、炒麦芽21份、小麦29份、牡蛎8份、栀子10份、酸枣仁11份、枸杞7份、大枣10份、龙眼肉8份、黑芝麻18份、核桃12份、阿胶50份,黄酒50份;所用枸杞为黑枸杞,所用小麦为黑小麦;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2次,每次2h,过滤合并提取液,减压浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒在5~25℃浸泡溶解,获得混合液;
3)将黑芝麻和核桃在分别在80~90℃下烘烤至含水率低于7%;将混合液煮沸、110~120℃加热,至混合液含水率15~25%时停止加热,获得黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,得阿胶糕。
实施例4
由以下重量份的原料制成:百合5份、茯苓10份、莲子5份、炒麦芽22份、小麦28份、牡蛎10份、栀子9份、酸枣仁12份、枸杞9份、大枣15份、龙眼肉5份、黑芝麻20份、核桃10份、阿胶50份,黄酒50份;所用枸杞为红枸杞,所用小麦为黑小麦;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2次,每次2h,过滤合并提取液,减压浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒在5~25℃浸泡溶解,获得混合液;
3)将黑芝麻和核桃在分别在80~90℃下烘烤至含水率低于7%;将混合液煮沸、110~120℃加热,至混合液含水率15~25%时停止加热,获得黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,得阿胶糕。
实施例5
由以下重量份的原料制成:百合10份、茯苓5份、莲子10份、炒麦芽17份、小麦32份、牡蛎5份、栀子12份、酸枣仁9份、枸杞12份、大枣5份、龙眼肉15份、黑芝麻10份、核桃20份、阿胶20份,黄酒20份;所用枸杞为黑枸杞,所用小麦为黄小麦;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2~3次,每次2~3h,过滤合并提取液,常压加热浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒在5~25℃浸泡溶解,获得混合液;
3)将黑芝麻和核桃在分别在90~100℃下烘烤至含水率低于7%;将混合液煮沸、100~110℃加热,至混合液含水率15~25%时停止加热,获得黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,得阿胶糕。
实施例6
本实施例的配方同实施例1;
制备方法按如下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取3次,每次2h,过滤合并提取液,减压浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,倒入黄酒在5~25℃浸泡溶解,浓缩、干燥得阿胶粉;
3)按重量份配比称取大枣、龙眼肉、黑芝麻和核桃分别在80~90℃下烘烤至含水率小于7%、粉碎过400目筛,混合均匀,得细粉;将浸膏粉、阿胶粉和细粉混合,干燥、过400目筛、灭菌得阿胶冲剂。
对比例
对比例1~3为申请人为了对比本发明的营养粉而设计的对比实施例。
对比例1
本对比例的配方和工艺与实施例1相同,区别在于:本对比例中将实施例1中的黑枸杞、黑芝麻、黑小麦对应替换为红枸杞、白芝麻、黄小麦。
对比例2
本对比例的配方和工艺与实施例1相同,区别在于:本对比例中阿胶替换为福牌阿胶。
对比例3
本对比例的配方和工艺与实施例1相同,区别在于:本对比例中未添加牡蛎、栀子和酸枣仁。
临床实践总结
以下为本发明的养心脾阿胶组合物可治疗的病症,以及病症的症状表现。
心脾两虚:心烦、心悸怔忡、失眠多梦、多汗、健忘、头晕、食欲不振、腹胀、大便稀溏、崩漏、便血、皮下出血、舌淡、脉细弱、面色萎黄、倦怠乏力、腰部与膝部酸软无力。
月经不调:月经延后、月经量少色淡、闭经,手足冰冷,面色萎黄、精神倦怠、腰部与膝部酸软无力。
临床诊疗报告
本发明的养心脾阿胶组合物的用法用量:
当本发明的养心脾阿胶组合物制成阿胶糕时,一日2次,每次服用15~20g,需饭前食用,服用期间忌食生冷、油炸、辛辣食物。1个月为一个疗程,疗程与疗程之间可连续服用。
当本发明的当本发明的养心脾阿胶组合物制成阿胶冲剂时,一日2次,每次服用10~15g,需饭前食用,服用期间忌食生冷、油炸、辛辣食物。需饭前食用,服用期间忌食生冷、油炸、辛辣食物。1个月为一个疗程,疗程与疗程之间可连续服用。
申请人分别对每个实施例获得的养心脾阿胶组合物进行临床诊疗。为了减小变量,对每个实施例临床诊疗时,心脾两虚病症选取100例患者进行统计,其中患者年龄20~40岁,男女各占50%;月经不调病症选取100例患者进行统计,患者年龄20~40岁,均为女性患者。疗效判断标准:依上述症状的改善状况将疗效分为治愈、显效和无效,按照前述病症分类使用有效效果所述的疗程内,总有效率为治愈率与显效率之和。连续使用6个疗程(6个月)后统计每个实施例的病例诊疗效果,对比例1~3的临床治疗方式同实施例1~6,统计结果如表1~9所示:
表1实施例1养心脾阿胶组合物的病例统计
。
表2实施例2养心脾阿胶组合物的病例统计
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表3实施例3养心脾阿胶组合物的病例统计
。
表4实施例4养心脾阿胶组合物的病例统计
。
表5实施例5养心脾阿胶组合物的病例统计
。
表6实施例6养心脾阿胶组合物的病例统计
。
表7对比例1组合物的病例统计
。
表8对比例2组合物的病例统计
。
表9对比例3组合物的病例统计
。
通过表1~9可看出,服用6个疗程后,实施例1~6的治愈率达到95~100%,有效率达到97~100%,证明多数患者在服用本发明的养心脾阿胶组合物后,其所患病症出现明显改善。
以上所述,仅是本发明的较佳实施例而已,并非是对本发明作其它形式的限制,任何熟悉本专业的技术人员可能利用上述揭示的技术内容加以变更或改型为等同变化的等效实施例。但是凡是未脱离本发明技术方案内容,依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与改型,仍属于本发明技术方案的保护范围。
Claims (9)
1.养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合5~10份、茯苓5~10份、莲子5~10份、炒麦芽17~22份、小麦28~32份、牡蛎5~10份、栀子9~12份、酸枣仁9~12份、枸杞9~12份、大枣5~15份、龙眼肉5~15份、黑芝麻10~20份、核桃10~20份、阿胶10~70份,黄酒10~70份。
2.根据权利要求1所述的养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合6~8份、茯苓7~9份、莲子7~9份、炒麦芽19~21份、小麦29~31份、牡蛎6~8份、栀子10~11份、酸枣仁10~11份、枸杞7~9份、大枣8~10份、龙眼肉8~10份、黑芝麻14~18份、核桃12~15份、阿胶15~50份,黄酒15~100份。
3.根据权利要求1所述的养心脾阿胶组合物,其特征在于,由以下重量份的原料组成:百合7份、茯苓8份、莲子8份、炒麦芽20份、小麦30份、牡蛎7份、栀子10.5份、酸枣仁11份、枸杞8份、大枣9~9.5份、龙眼肉9~9.5份、黑芝麻16~17份、核桃13~14份、阿胶20~40份,黄酒40~120份。
4.根据权利要求1所述的养心脾阿胶组合物,其特征在于:所述的阿胶和黄酒按照质量比1:1添加。
5.权利要求1~3任意一项所述的养心脾阿胶组合物的制备方法,其特征在于,制备成阿胶糕,包括以下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2~3次,每次2~3h,过滤合并提取液,浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,加入浸膏粉,倒入黄酒浸泡溶解,获得混合液;
3)将黑芝麻和核桃在烘烤至酥脆;将混合液煮沸、熬制呈黏稠膏体,加入大枣、龙眼肉、黑芝麻和核桃,搅拌均匀,趁热倒入模具中,冷却脱模获得坯体,切割坯体,即得。
6.根据权利要求5所述的养心脾阿胶组合物的制备方法,其特征在于:所述的烘烤至酥脆的具体操作为:将黑芝麻和核桃分别在80~100℃下烘烤至含水率低于7%。
7.根据权利要求5所述的养心脾阿胶组合物的制备方法,其特征在于:所述的熬制呈黏稠膏体的具体操作为:将混合液加热至100~120℃,至混合液含水率15~25%时停止加热,获得黏稠膏体。
8.权利要求1~3任意一项所述的养心脾阿胶组合物的制备方法,其特征在于,制备成阿胶冲剂,包括以下步骤:
1)百合、茯苓、莲子、炒麦芽、小麦、牡蛎、栀子、酸枣仁和枸杞混合,加水,90~95℃热回流提取2~3次,每次2~3h,过滤合并提取液,浓缩、干燥、破碎得浸膏粉;
2)按重量份配比称取阿胶,倒入黄酒浸泡溶解,浓缩、干燥得阿胶粉;
3)按重量份配比称取大枣、龙眼肉、黑芝麻和核桃分别脱水、粉碎过100~500目筛,混合均匀,得细粉;将浸膏粉、阿胶粉和细粉混合,干燥、过100~500目筛、灭菌得阿胶冲剂。
9.根据权利要求8所述的养心脾阿胶组合物的制备方法,其特征在于:步骤3)所述的脱水的具体操作为:在80~100℃下烘烤至含水率低于7%,或者,采用真空冷冻干燥至含水率低于7%。
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