CN106511594A - Traditional Chinese medicine composition for treating insomnia - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating insomnia. The traditional Chinese medicine composition is characterized by being made of the following Chinese herbal medicines in parts by weight: 30-100 parts of gynostemma pentaphylla, 30-50 parts of keels, 10-30 parts of radix rehmanniae, 40-50 parts of magnets, 15-25 parts of wild jujube seeds, 15-20 parts of roasted polygala tenuifolia, 20-25 parts of schisandra chinensis and 5 parts of licorice.

Description

A kind of Chinese traditional medicine composition for treating insomnia disease

Technical field

The invention belongs to traditional Chinese medicine in treating insomnia disease technical field, and in particular to eight kinds of Chinese herbal medicines as raw material make for The decoction for the treatment of insomnia disease.

Background technology

Insomnia is referred to cannot fall asleep or cannot keep sleep state, cause not having enough sleep.Hinder also known as falling asleep and maintaining to sleep Hinder, be that a variety of causes causes difficulty falling asleep, Depth of sleep or frequency be too short, early awakening and the length of one's sleep not enough or of poor quality etc., be A kind of common disease.

Insomnia often brings greatly pain and psychological burden to patient, can cause body because of abuse insomnia drug again Body is otherwise uncomfortable.

The clinical manifestation of vigilance disorders shape

1st, poor sleeping quality：Although many patients can fall asleep, can feeling that sleep can not be recovered from fatigue, after waking up, still there is sense of fatigue.

2nd, sleep sensory disturbance：The sense of reality of sleep insuffience, although many patients can fall into a profound sleep, believes firmly oneself after waking up Do not fall asleep, and the people of chummery or spouse are we were telling you he is snoring always.

3rd, the shallow easy daydream of sleep：Patient's self-induction sleeps unreal, a night all seemingly sleep it is non-sleep, one close one's eyes be exactly dream, one has Sound is just waken up, some early awakenings, no matter what time falling asleep, the three in the morning is accurate awake, falls asleep again and is more difficult to, have to stare to daybreak after waking up, Insomnia patientses both know about, and are most painful when can't fall asleep.Patient Jing also often has nightmares, from terrified thrilling dream Wake up with a start in border, in a cold sweat, nervous palpitaition, pale complexion dare not again be fallen asleep.This is also the performance of insomnia.

4th, difficulty falling asleep：Toss about in bed, time for falling asleep postpones 1-3 hour than ever, patient says original also very tired, also wants to Sleep, it is exactly to can't fall asleep that can lie on a bed, and that what is tossed about thinks some things topsy-turvy, and calm not get off, the length of one's sleep is bright It is aobvious to reduce.Some patients are to feel sleepy daytime, drowsy, listless, night excited egersis, study, have a meeting, attend class and beat Doze, see that TV is leaned against on sofa just sleeping, toward on bed once lying and spiritual can say.

Pathology and disease mechanism

Sleep is divided into two periods according to electroencephalogram, electromyogram change, i.e., non-fast dynamic phase (HREM) and the rapid eye movement period of sleeping (REM) when, the phase is moved in non-fast dormancy, Muscle tensility is reduced, and without obvious eye movement, electroencephalogram shows slowly and synchronously, and this phase is waken up Then feel drowsiness.During rapid eye movement period, Muscle tensility is substantially reduced, and quick horizontal eye movement occurs, and electroencephalogram shows and class during awakening As state, this wakes up phase, Clear consciousness, and without taediumvitae, colourful dream occurs in this phase.

Modern medicine study finds that brain stem tail end has very important relation with sleep, it is considered to be the institute of sleep center Cause hypersomnia in, various excitant pathologies in this position, and the sleep that causes of destructive pathology is reduced.It has further been found that sleep When have the participation of nervus centralis media, stimulate serotoninergic neuron or injection 5-HTP, non-rapid eye movement period can be produced Sleep, and Serotonin Antagonist is given, produce sleep and reduce.Using norepinephrine antagonistic, then rapid eye movement sleep subtracts It is few, and norepinephrine excitomotor is given, rapid eye movement sleep increases.

The reason for which is common is as follows：

1. the insomnia caused by mental element：Stress, anxiety, fear, excitement etc. can cause of short duration insomnia, be mainly into Sleep difficult and easily wake up with a start, after mental element is released, insomnia can improve.Neurasthenia patient often tells difficulty of falling asleep, and sleep is not Show that the length of one's sleep is not reduced in deep, dreaminess, but EEG, and the time and number of times awakened increased, this kind of disease People often has the symptom such as headache, dizziness, forgetful, weak, emotional.Show early awakening more the insomnia of depression or sleep is not deep, brain electricity Figure is traced and shows that the awakening time is obviously prolonged.Mania performance is fallen asleep difficult even egersis whole night.Schizophrenia is because being vainly hoped Impact can show difficulty falling asleep and enter sleep not deeply.

2. the insomnia that Physical factors cause：Pain that various physical diseases cause, sufferings, nasal obstruction, expiratory dyspnea, asthma, Cough, frequent micturition, Nausea and vomiting, abdominal distension, diarrhoea, palpitaition etc. can cause fall asleep difficulty and depth of sleeping.

3. physiologic factor：As the change of living and working environment arrives strange land, unused environment, drink strong tea coffee etc. with first Can cause insomnia, after short-term regulation insomnia can improve.

4. the insomnia that drug factors cause：Reserpine, amphetamine, thyroxine, caffeine, aminophylline etc. can cause mistake Insomnia after dormancy, drug withdrawal can disappear.

5. brain dispersivity pathology：Slow poisoning, endocrine system disease, Nutrition and Metabolism obstacle, cerebral arteriovenous malformation etc. it is various because The brain dispersivity pathology that element causes, insomnia are often early symptom, and the performance length of one's sleep is reduced, interruption is easily waken up, the sound sleep phase disappears, The drowsiness and disturbance of consciousness is may occur in which during aggravation.

Doctor trained in Western medicine clinical treatment is generally the application of hypnotic sedative agent.

Traditional Chinese medicine in treating insomnia disease is typically controlled by following differentiation of symptoms and signs for classification of syndrome opinion：

1. liver depression forming fire symptom：It is insomnia, mood being irritable and getting angry easily, do not feel like eating, thirst and liking drink, hot eyes day are bitter, dark urine, Constipation.Blue or green red, yellow tongue fur, stringy and rapid pulse.

Syndrome analysis：Sorrow raged impairing liver, liver lose bar and reach, and qi depression transforming into fire, disturbing the mind upwards are then insomnia；Liver-qi attacking stomach does not then think drink Food；Liver depression forming fire surveys being irritable and getting angry easily；Irascibility takes advantage of stomach, stomach energy then thirst and liking drink；Disturb on burning hot, therefore hot eyes mouth is general；Dark urine, greatly Constipation is tied；Tongue is red, and yellow tongue fur, wiry and frequent pulse are thermal image.

2. symptom is disturbed in phlegm heat：It is insomnia, vexed, excessive sputum and oppression feeling over the chest dislikes food heating installation, nausea and acid regurgitation, bitter taste, heaviness of the head with dazzle.Tongue It is greasy and yellow, slippery and rapid pulse.

Syndrome analysis：Place food is stagnated, and product is wet into phlegm, because of disease heat, disturbs then dysphoria and insomnia in phlegm heat；Phlegm wet heap soil or fertilizer over and around the roots is held back in, Functional activity of QI being not smooth, it is stomach Qi rising, therefore see uncomfortable in chest, dislike food heating installation or evil of vomitting；Clear sun is covered, therefore heaviness of the head with dazzle；Yellow and greasy fur, slippery and rapid pulse is That what is stopped in phlegm heat, place food levies.

3. fire excess from yin deficiency symptom：Dysphoria and insomnia, palpitation and restlessness, dizziness and tinnitus are forgetful, and soreness of the loins and nocturnal emission is dysphoria in chestpalms-soles, dry Tianjin is few.Tongue is red, thready rapid pulse.

Syndrome analysis：The deficiency of the kidney yin, it is impossible to above meet at the heart, hyperactivity of heart-liver fire, abnormal heat disturb god, therefore dysphoria and insomnia, palpitation and restlessness； Kidney essense loss, brain are hollow, therefore dizzy, tinnitus, it is forgetful；Lose and support the then soreness of waist in waist mansion；Essence closes not solid, so nocturnal emission；Dry mouth and lack of saliva, It is dysphoria in chestpalms-soles；Tongue is red, thready rapid pulse be it is fire excess from yin deficiency as.

4. insufficiency of heart and spleen symptom；Dreaming often and waking easily, palpitation and amnesia are had a dizzy spell, and lassitude of the limbs and mind distastes for food, lustreless complexion. Tongue is weak, tongue are thin, and arteries and veins is thin and delicate.

Syndrome analysis：Heart spleen virtual loss, blood not nourishing heart are had ants in one's pants, therefore dreaming often and waking easily, forgetful, palpitaition；Deficiency of qi and blood, no Can on give in brain, lucid yang failing to raise, therefore have a dizzy spell；The deficiency of blood is not flourish, therefore lustreless complexion, tongue is weak；Board loses strong fortune, then distaste for food； The few deficiency of vital energy of blood, therefore lassitude of the limbs and mind, deficient and weak pulse.

5. heart and gallbladder deficiency of vital energy symptom：It is insomnia dreaminess, it is easy to wake up with a start, timidity and palpitation is when anything crops up susceptible to fright, shortness of breath and lassitude, clear abundant urine. Tongue is weak, small and wiry pulse.Syndrome analysis：Have a guilty conscience then confused and worried, milk-livered then susceptible to fright and fear, therefore dreaming often and waking easily, palpitaition are susceptible to fright；Shortness of breath is tired It is idle, clear abundant urine for the deficiency of vital energy as；Tongue is weak, small and wiry pulse are the performance of insufficiency of vital energy and blood.

Open source information shows, the traditional Chinese medical science presses above-mentioned disease medication, and principle of reatment is tonifying heart and spleen, nourishing blood and tranquilization；Nourishing Yin and falling fire, Clearing away the heart fire and tranquillizing；Restoring normal coordination between heart and kidney；Soothing the liver nourishing blood and tranquilization；Beneficial gas are relieving convulsion, tranquilizing the mind；Reducing phlegm and fever, mental-tranquilization；It is stagnant with stomachization Deng. meanwhile, also aid in following method integrated treatment：The sick relaxation therapy of insomnia, the sick anion therapy of insomnia, foot disease balneation of having a sleepless night The general effects such as method, the sick tonic therapy of insomnia are relatively good.

The content of the invention：

The present invention is aiming at the defect of the doctor trained in Western medicine clinical treatment present situation of above-mentioned insomnia, tcm clinical practice and carries out dialectical controlling again Treat and unified treatment standard cannot be provided and invent a kind of to the effective Chinese traditional medicine composition of various clinical syndromes, the Chinese traditional medicine composition Can efficiently and effectively relieving insomnia, be effectively increased rapid-eye-movement sleep's time of patient and his family, reduce patient to sedative hypnotic drug according to Rely, have no adverse reaction, herbal medicine that is harmless and constituting the Chinese medicine is simple and easy to get.

The present invention technical solution be：A kind of Chinese traditional medicine composition for treating insomnia, it is characterised in that it is by following heavy Decoction made by the Chinese herbal medicine of amount part proportioning：

Gynostemma pentaphylla 30-100, keel 30-50, radix rehmanniae recen 10-30, magnetite 40-50, spina date seed 15-25, honey-fried RADIX POLYGALAE 15-20, Fruit of Chinese magnoliavine 20-25, Radix Glycyrrhizae 5.During treatment insomnia disease, by above-mentioned weight, part proportioning, it is decocted in water for oral dose, it is daily one.

The important feature of the present invention is the nutrient content enriched in medicament, each raw material components ingredient of the invention and work( Can cure mainly as follows：

Gynostemma pentaphylla：Seven leaf courages, Pentapanax leschenaultii etc. are called, and are originated in drought each province, Shaanxi are mainly distributed in China Flat interest, Structure, Hunan, Hubei, Yunnan, Guangxi etc. save, and the herbal medicine is sweet, and slight bitter is cold in nature, enters lung, the heart, kidney channel.It is modern Medical research shows that gynostemma pentaphylla contains the gynosaponin of abundant similar panaxoside and the amino acids thing abundanter than ginseng Matter, it is clinical to confirm which has anti-aging effects, human body cell vigor can be strengthened, enhanced metabolism, improve organism metabolism, raising is exempted from Epidemic disease function, dispelling fatigue improve the adaptability to changes of body, improve the health care of sleep, and the Clinical pharmacological efficiency such as improve a poor appetite.Tcm clinical practice is total Knot thinks that gynostemma pentaphylla is the good medicine of eliminating inflammation and expelling toxin, with benefiting qi for tranquillization, hypotensive, preventing phlegm from forming and stopping coughing, it is clearing heat and detoxicating the effect of, the people Between be called " mystery " " elixir grass, be usually used in the diseases such as poliosis, high fat of blood, headache, insomnia.

Keel：Call five OS DRACONISs, green grass or young cropsization keel, white keel etc..This product is ancient times mammal, such as rhinoceros class, deer class, ox Class, as the Skeletal Fossils of class etc..The flavour of a drug are sweet, puckery, mild-natured.Enter liver and kidney channel.Modern medicine study shows, the suspension of keel Yellow Jackets hypnosis rate can be dramatically increased, is shown with certain sedation.Tcm clinical practice is summarized and is thought, keel are to calm the nerves Astringent or styptic treatment for spontaneous sweating good medicine, only lose with tranquilizing mind, controlling nocturnal emission with astringent drugs, calming the liver, myogenic sore the effects such as.It is usually used in palpitation and being susceptible to fright, has a sleepless night The diseases such as dreaminess.

Magnetite：For oxide-based mineral spinelle race magnetic iron ore, main (Fe304) containing ferroso-ferric oxide.Jing after excavation, remove Miscellaneous stone is formed.The ground such as Hebei, Shandong are distributed in, the flavour of a drug are salty, cold in nature, enter liver, the heart, kidney channel.Tcm clinical practice is summarized and is thought：Magnetite It is with tranquillizing the mind by relieving convulsion, calming the liver, hearing-improing and eyesight improving, effect that gas of receiving is relievingd asthma.It is usually used in insomnia of palpitating with fear, has a dizzy spell, depending on thing dusk Flower, Hiccough and deaf, kidney deficiency asthma.

The dried rhizome of rehmannia：Another name ground marrow, mountain cigarette root etc., are the rhizomes of scrophulariaceae rehmannia glutinosa plant or bosom celebrating glutinous rehmannia, are dried and be used as medicine The referred to as dried rhizome of rehmannia, has product all over China, and prepared rhizome of rehmannia is the Preparation process product of the dried rhizome of rehmannia, and the herbal medicine is sweet, cold in nature.Enter the heart, liver, kidney Jing.Modern pharmacological research shows that radix rehmanniae recen has the effect of the propagation for promoting marrow hemopoietic stem cells, promotes blood clotting and liter High peripheral leukocytes, strengthen immunologic function, liver protection, reduce the effect such as blood sugar, diuresis.Tcm clinical practice thinks that the dried rhizome of rehmannia is that cool blood is grown Cloudy good medicine, with clearing heat and cooling blood, yin-nourishing, the effect promoted the production of body fluid, can be used for the diseases such as pyreticosis, tongue polydipsia.

Spina date seed：Another name jujube kernel, jujube nucleus, mountain jujube benevolence etc..Pulp, nucleocapsid are gone by Rhamnaceae arbor wild jujube ripening fruits, Seed is collected, is dried and is formed.The ground such as Henan, Hebei are originated in mainly, the flavour of a drug, property are sweet, taste is put down.The thoughts of returning home, spleen, liver, gallbladder channel.It is modern Medical research shows that spina date seed contains the medicinal ingredients such as abundant jujuboside betulic acid, betulin, and these compositions are demonstrate,proved It is real that there is the pharmacological action for improving the health care of sleep.Tcm clinical practice is summarized and is thought, spina date seed is the good medicine that nourishing the liver is allayed excitement, with nourishing the liver, rather Effect of heart and tranquilizing mind, arrest sweating.Flat liver and qi is can be used to, is moistened the lung and nourish yin, middle benefit gas dampness removing holds back gas hidroschesis, and beneficial will is breathed out surely, hearing-improing and eyesight improving Deng.

Honey-fried RADIX POLYGALAE：Call little careless, thin grass, Chicken Drumsticks, Roots of Polygala tenuifolia, line tea etc..The province such as Shaanxi, China, Shanxi is originated from mainly Part, it is herbaceos perennial.Honey-fried RADIX POLYGALAE is to decoct out fried liquid by broken Radix Glycyrrhizae, and concentration adds net polygala root again, simmers in water to soup It is sucked, takes out drying and form, the flavour of a drug is bitter, pungent, warm in nature.Enter the heart, lung, kidney channel.Modern medicine study shows that honey-fried RADIX POLYGALAE contains Saponin, can get two kinds of sapogenin crystallizations, presenegenin A and presenegenin B after hydrolysis.Clinical testing confirms which has Calm, sleeping pharmacological action.Tcm clinical practice is summarized and is thought, polygala root has tranquilize the mind and promote the intelligence, eliminating the phlegm, Xie Yu.Palpitation with fear can be controlled, is good for Forget, have a sleepless night,.It is usually used in insomnia and dreamful sleep, forgetful palpitation with fear that breakdown of the normal physiological coordination between the heart and the kidney causes, it is wandering to wait disease.

The fruit of Chinese magnoliavine：The distant five tastes of another name, the western five tastes, in addition to Xinjiang, Qinghai, each province is distributed and cultivates for China.Five Taste is divided into two kinds of south, north, and drug effect is the same.The taste herbal medicine taste is sour, sweet, warm in nature.Enter lung, the heart, kidney channel.Modern medicine study table Bright, fruit of Chinese magnoliavine water decoction contains abundant organic acid, vitamin, flavonoids, phytosterol and lignan, because lignan has Potent reactivation, so the fruit of Chinese magnoliavine has can lower the Clinical pharmacological efficiencies such as tired physical fatigue sense, sedation.TCM Bed is summarized and is thought, the fruit of Chinese magnoliavine is the Chinese medicine of famous kidney calming, has nourishing strong, astringe the lung only cough, nourishing generate fluid, kidney calming Effect, can be used for the diseases such as insomnia forgetfulness.

Example：Patient Liu, female, 44 years old, ancient Chinese prose township of Dahua Yao Nationality Autonomous County Yi He people from villages, main suit's insomnia were nearly more than 3 Month, medical on April 25th, 2016, since readme 3 months, dreaming often and waking easily, palpitation and amnesia are had a dizzy spell, lassitude of the limbs and mind, diet Tasteless, daytime, spirit was prosperous, and personality is more irritable, cold perspiration.Have a medical check-up and see lustreless complexion.Body is more fat, and tongue is weak, tongue are thin, and arteries and veins is thin and delicate, Heel has tenderness, thready rapid pulse.Tongue is thin white.Once the sedatives such as amber, cortex albiziae were taken invalid.Auxiliary examination：Routine blood test (one), urine Conventional (one)；Electrocardiogram (one)；Cranium brain CT examination image is without exception, clarify a diagnosis for：Insomnia disease.Then gynostemma pentaphylla 80 is issued, dragon Bone 50, radix rehmanniae recen 25, magnetite 45, spina date seed, 20, honey-fried RADIX POLYGALAE 18, the fruit of Chinese magnoliavine 20, Radix Glycyrrhizae 5.In grams, 7 doses are issued, is cured Patient and his family are advised, is decocted in water for oral dose, it is daily one.When patient and his family two examine, insomnia has been alleviated, and can no longer take hypnotic sedative agent can Normal to sleep, doctor's advice patient and his family are gone to a doctor as early as possible if any discomfort.

Claims (1)

1. the invention belongs to traditional Chinese medicine in treating insomnia disease technical field, and in particular to made for controlling with eight kinds of Chinese herbal medicines as raw material Treat the Chinese traditional medicine composition of insomnia disease, it is characterised in that it is made up of the Chinese herbal medicine of following weight parts proportioning：Gynostemma pentaphylla 30-100, dragon Bone 30-50, radix rehmanniae recen 10-30, magnetite 40-50, spina date seed 15-25, honey-fried RADIX POLYGALAE 15-20, fruit of Chinese magnoliavine 20-25, Radix Glycyrrhizae 5.