CN106492033A - A kind of treat medicine of chronic rhinitiss and preparation method thereof - Google Patents

A kind of treat medicine of chronic rhinitiss and preparation method thereof Download PDF

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CN106492033A
CN106492033A CN201611113567.5A CN201611113567A CN106492033A CN 106492033 A CN106492033 A CN 106492033A CN 201611113567 A CN201611113567 A CN 201611113567A CN 106492033 A CN106492033 A CN 106492033A
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冉兆斌
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Abstract

The invention discloses a kind of treat medicine of chronic rhinitiss and preparation method thereof, which is mainly prepared from according to a certain weight ratio by Gypsum Fibrosum, Radix Codonopsis, Flos Magnoliae, Radix Glycyrrhizae, Folium Mori, Semen Cuscutae, Spica Prunellae, the Radix Angelicae Dahuricae, Folium Eriobotryae, Flos Lonicerae, Radix Saposhnikoviae, Rhizoma Ligustici, Herba Centipedae, Semen Sojae Preparatum, Stigma Croci, Folium Perillae, Herba Houttuyniae, medicine of the present invention has expelling pathogenic wind and restoring the functions of orifices in face, open lung qi dispersing gas, lowering the adverse-rising QI to resolve phlegm, with middle emergency, lung moistening is detoxified, the function of spleen reinforcing stomach reinforcing, for treating chronic rhinitiss instant effect, good effect, do not recur.

Description

A kind of treat medicine of chronic rhinitiss and preparation method thereof
Technical field
The present invention relates to a kind of treat medicine of chronic rhinitiss and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Chronic rhinitiss are the chronic inflammatory diseases of nasal mucosa and Submucosa.It is mainly characterized by inflammation continue more than three months or Recurrent exerbation, protracted course of disease, intermission can not also recover normal, and without clear and definite pathogenic microorganism, with different degrees of nose Plug, secretions increase, tunica mucosa nasi swelling such as thickens at the obstacle.The traditional Chinese medical science then thinks that chronic rhinitiss and deficiency of both the splenic and pulmonary QI, lung-heat accumulate product, gas Stagnant blood stasis is relevant.Due to western medicine large side effects, therefore people are very big to the Chinese medicine presence of effectively treatment chronic rhinitiss Demand, up to now, it has not been found that with regard to the present invention relevant report.
Content of the invention
The present inventor have found effectively treatment chronic finally according to the research and the checking repeatedly of clinical trial of theory of Chinese medical science The medicine of rhinitis, so that complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment chronic rhinitiss.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select Gypsum Fibrosum, Radix Codonopsis, Flos Magnoliae, Radix Glycyrrhizae, Folium Mori, Semen Cuscutae, Spica Prunellae, the Radix Angelicae Dahuricae, Folium Eriobotryae, gold Flos Lonicerae, Radix Saposhnikoviae, Rhizoma Ligustici, Herba Centipedae, Semen Sojae Preparatum, Stigma Croci, Folium Perillae, Herba Houttuyniae, Radix Platycodoniss, Fructus Gardeniae, Radix Scutellariae, Herba Lophatheri, company Stick up, Radix Adenophorae, Herba Menthae, Herba Epimedii, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, Cortex Mori, Fructus Arctii, Herba Ephedrae, Semen Armeniacae Amarum are combined preparation, by these Drug regimen causes each efficacy of drugs to produce synergism such that it is able to effectively treatment chronic rhinitiss.Wherein, from Gypsum Fibrosum be because For its property acrid-sweet flavor, tremble with fear, enter lung, stomach, raw with having expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst to control calentura high fever and do not move back, vexed god Dusk, delirium go mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach headache due to fire-evil, toothache, hyperactivity of toxic heat, spot dermexanthesis, and dispute is given birth to Skin ulcer, forges deposited promoting tissue regeneration and ulcer healing, and external treatment ulcer sores are burst and do not withdrawn, the burning hot wound of soup.It is because that its nature and flavor is sweet from Radix Codonopsis, puts down, enter Handss, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, and control weakness of the spleen and stomach, and deficiency of both QI and blood, fatigue and lack of strength, lack of appetite are thirsty, Chronic diarrhea, proctoptosis.It is because that its nature and flavor is pungent from Flos Magnoliae, temperature enters lung, stomach, has a wind-dispelling, sensible function, controls headache, nasal sinusitis, Obstructed, the toothache of nasal obstruction.Its property sweet taste is because from Radix Glycyrrhizae, enters spleen, stomach, lung meridian, had and middle emergency, lung moistening, detoxified, reconciled The function of all medicines, processs with weakness of the spleen and stomach is controlled, and lack of appetite, loose stool of suffering from abdominal pain, overstrain generate heat, and consumptive lung disease is coughed, cardiopalmus, shy carbuncle, raw with controlling pharynx Larynx swells and ache, peptic ulcer, ulcer sores, solves poison of drug and alimentary toxicosis.Its nature and flavor bitter sweet is because from Folium Mori, tremble with fear, enter lung, Liver Channel, has expelling wind and clearing away heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens to generate heat, and headache, conjunctival congestion are thirsty, cough due to lung-heat, migratory arthralgia, urticaria, Lower limb elephatiasis.Its property acrid-sweet flavor is because from Semen Cuscutae, is put down, is entered liver and kidney channel, have invigorating the liver and kidney, beneficial marrow, the work(of improving eyesight Can, soreness of waist and knee joint to be controlled, is passed out semen, is quenched one's thirst, dripping urination, mesh are dark.Its nature and flavor toil is because from Spica Prunellae, is trembled with fear, enter liver, gallbladder Through, there are liver heat removing, the function of eliminating stagnation to control scrofula, goiter, acute mastitis, breast carcinoma, mesh pearl nyctalgia, photophobia are shed tears, and the vertigo, mouth eye are askew Tiltedly, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.It is because that its nature and flavor is pungent from the Radix Angelicae Dahuricae, temperature, Enter lung, spleen, stomach, have a wind-dispelling, dampness, detumescence, the function of pain relieving control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-dampness stomachache, Intestines wind anal fistula, leucorrhea with red and white discharge, ulcer sores, skin is dry itches, scabies.It is because that its nature and flavor is bitter from Folium Eriobotryae, cool, return lung, stomach Through having lung heat clearing stomach function regulating, lowering the adverse-rising QI to resolve phlegm to control lung-heat phlegmatic cough, hemoptysis, epistaxis, stomach energy is vomitted the sound of vomiting.Its nature and flavor is because from Flos Lonicerae Sweet, tremble with fear, enter lung, stomach, have heat clearing away, the function of removing toxic substances to control warm disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Choosing Its property acrid-sweet flavor is because with Radix Saposhnikoviae, temperature enters bladder, lung, spleen channel, delivers, wind-dispelling wins wet, the function of pain relieving, controls diseases caused by exogenous pathogenic factor wind Cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, extremity contraction urgency, tetanus.It is because that its nature and flavor is pungent from Rhizoma Ligustici, Temperature, returns bladder warp, has cold expelling wind-dispelling, and the function of removing damp and stopping pain, for anemofrigid cold, mountain peak top pain.From Herba Centipedae be because Pungent for its nature and flavor, temperature enters meridian of Hand-TAI YIN edema caused by disorder of QI, has wind-dispelling, cold expelling to win wet, removing nebula, and the function of stuffy nose relieving plug cures cold, asthma of cold-type, Sore throat, pertussis, eruptive disease are suffered from abdominal pain, amebic dysentery, malaria, infantile malnutrition with diarrhea, nasal sinusitis, polyp, and corneal nebula is puckery to itch, ecthyma, scabies, traumatic injury.Choosing It is because that its nature and flavor is bitter with Semen Sojae Preparatum, trembles with fear, enter lung, stomach, have and induce sweat, relieving restlessness, Xuan Yu, the function of removing toxic substances is controlled typhoid disease, trembled with fear Heat, headache are fidgety, uncomfortable in chest.It is because that its nature and flavor is sweet from Stigma Croci, puts down, enter the heart, Liver Channel has blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens Function, controls troubled thoughts pent-up, and chest and diaphragm painful abdominal mass is vexed, spits blood, and typhoid fever goes mad, and shies and is afraid of in a trance, and women's amenorrhea, postnatal blood stasis are suffered from abdominal pain, fall flutter swollen Bitterly.It is because that its nature and flavor is pungent from Folium Perillae, temperature enters lung, spleen channel, delivers, cold expelling, qi-regulating, and the function of battalion, and cure cold wind Cold, fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen, frequent fetal movement, and can solving toxin of fish and crab.Its nature and flavor is because from Herba Houttuyniae Pungent, to tremble with fear, enter meridian of Hand-TAI YIN, have a heat-clearing and toxic substances removing, the function of inducing diuresis to remove edema controls pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, Leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.Its nature and flavor toil is because from Radix Platycodoniss, is put down, is entered lung, stomach, have out Lung qi dispersing gas, the function of eliminating the phlegm evacuation of pus control exogenous cough, and laryngopharynx swelling and pain, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery are suffered from abdominal pain.From Fructus Gardeniae It is because that its nature and flavor is bitter, trembles with fear that enter the heart, liver, lung, stomach have a heat clearing away, calentura restlessness of asrhenia type and insomnia is controlled in pathogenic fire purging, the function of removing heat from blood, jaundice, Gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, and epistaxis, dysentery, hematuria, pathopyretic ulcer are sprained and swollen and ache.Its property is because from Radix Scutellariae Bitter in the mouth is trembled with fear, and enters cardiopulmonary, gallbladder, large intestine channel, has removing the relative excess fire, except damp and hot, the function of arresting bleeding and miscarriage prevention, controls high fever excessive thirst, cough due to lung-heat.Choosing Its property slightly sweet flavor is because with Herba Lophatheri, is trembled with fear, enter the heart kidney two warp has clearing away heart-fire, heat clearing away and restlessness relieving, the function of diuresis to control calentura mouth Yearningly, vexed, hot urination, stranguria with turbid discharge, erosion of the oral mucosa tongue boil, gingival swelling and pain.It is because that its nature and flavor is bitter from Fructus Forsythiae, cool, enter the heart, liver, gallbladder Through, there is heat clearing away, detoxify, eliminating stagnation, the function of detumescence control warm, erysipelas, macule, large carbuncle pyogenic infections, scrofula, urine leaching closes.From south Radix Adenophorae (Radix Glehniae) is because that its nature and flavor is sweet, is slightly cold, attaches to the lung and stomach meridians, and has nourishing YIN and clearing away lung-heat, resolving sputum, the function of QI invigorating to control lung-heat type cough, the deficiency of YIN Phthisical cough, dry cough expectorant are sticked, deficiency of both vital energy and Yin, restlessness and fever with thirst.It is because that its nature and flavor is pungent from Herba Menthae, cool, enter lung, Liver Channel, have dispelling wind, dissipate Heat, wards off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, sore scabies, addiction Rash.Its property acrid-sweet flavor is because from Herba Epimedii, temperature enters liver and kidney channel, has kidney invigorating and YANG supporting, the function of expelling wind and removing dampness to control sexual impotence not Lift, dribbling urination, muscles and bones contraction urgency, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.Its nature and flavor is because from the Rhizoma Atractylodis Macrocephalae Bitter sweet, temperature, enters spleen, stomach, has a spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, the few gas of asthenia are empty Swollen, to have loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria are dizzy, and spontaneous perspiration, nausea are uneasy.From being because its nature and flavor Radix Ophiopogonis Sweet slight bitter, trembles with fear, enters lung, stomach, heart channel, have nourishing YIN and moistening the lung, relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid to control dryness of the lung dry cough, spits blood, coughs up Blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, clear thirsty, calentura Tianjin is hindered, dry mouth and throat, constipation.It is because that its nature and flavor is sweet from Cortex Mori, Cold, enter lung, spleen channel, have eliminating pathogen from the lung for relieving asthma, the function of line water detumescence to control dyspnea and cough due to lung-heat, spit blood, edema, tinea pedis, dysuria.Choosing It is because that its nature and flavor is worked hard with Fructus Arctii, cool, enter lung, stomach, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating to control wind Heat cough, laryngopharynx swelling and pain, macule are impermeable, and rubella is had an itch, carbuncle sore tumefacting virus.From Herba Ephedrae be because its nature and flavor work hard, temperature, enter lung, Bladder warp, has diaphoresis, relievings asthma, the function of diuretic, controls typhoid fever table reality, and fever with chills is lossless, headache nasal obstruction, arthralgia, cough Asthma, edema due to wind pathogen edema, dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella itch.It is because that its nature and flavor is bitter from Semen Armeniacae Amarum, temperature, Poisonous, enter lung, large intestine channel, have expelling phlegm for arresting cough, relieving asthma, the function of intestine moistening controls exogenous cough, dyspnea with fullness of the chest, sore throat, dry constipation of intestines.
Specific embodiment
The drug dose of instant component is also that inventor is drawn through groping in a large number to summarize, and the consumption of each component is following heavy All there is in the range of amount preferable curative effect:
10-20 gram of Gypsum Fibrosum, 5-15 gram of Radix Codonopsis, 10-20 gram of Flos Magnoliae, 7-12 gram of Radix Glycyrrhizae, 5-15 gram of Folium Mori, 10-20 gram of Semen Cuscutae, summer 10-20 gram of hay, 10-15 gram of the Radix Angelicae Dahuricae, 10-20 gram of Folium Eriobotryae, 5-15 gram of Flos Lonicerae, 5-15 gram of Radix Saposhnikoviae, 5-15 gram of Rhizoma Ligustici, goose is not 5-15 gram of food grass, 10-20 gram of Semen Sojae Preparatum, 5-10 gram of Stigma Croci, 5-15 gram of Folium Perillae, 10-20 gram of Herba Houttuyniae, 5-15 gram of Radix Platycodoniss, 10-20 gram of Fructus Gardeniae, 5-15 gram of Radix Scutellariae, 5-15 gram of Herba Lophatheri, 5-15 gram of Fructus Forsythiae, 10-20 gram of Radix Adenophorae, 5-15 gram of Herba Menthae, excessive sheep 10-15 gram of the leaves of pulse plants, 5-15 gram of the Rhizoma Atractylodis Macrocephalae, 5-15 gram of Radix Ophiopogonis, 10-15 gram of Cortex Mori, 5-15 gram of Fructus Arctii, 3-9 gram of Herba Ephedrae, Semen Armeniacae Amarum 10- 15 grams.
Preferably:
15 grams of Gypsum Fibrosum, 10 grams of Radix Codonopsis, 15 grams of Flos Magnoliae, 9 grams of Radix Glycyrrhizae, 10 grams of Folium Mori, 15 grams of Semen Cuscutae, 15 grams of Spica Prunellae, the Radix Angelicae Dahuricae 12 Gram, 15 grams of Folium Eriobotryae, 10 grams of Flos Lonicerae, 10 grams of Radix Saposhnikoviae, 10 grams of Rhizoma Ligustici, 10 grams of Herba Centipedae, 15 grams of Semen Sojae Preparatum, 8 grams of Stigma Croci, 10 grams of Folium Perillae, 15 grams of Herba Houttuyniae, 10 grams of Radix Platycodoniss, 15 grams of Fructus Gardeniae, 10 grams of Radix Scutellariae, 10 grams of Herba Lophatheri, 10 grams of Fructus Forsythiae, Radix Adenophorae 15 Gram, 10 grams of Herba Menthae, 12 grams of Herba Epimedii, 10 grams of the Rhizoma Atractylodis Macrocephalae, 10 grams of Radix Ophiopogonis, 12 grams of Cortex Mori, 10 grams of Fructus Arctii, 6 grams of Herba Ephedrae, Semen Armeniacae Amarum 12 Gram.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Gypsum Fibrosum:Miscellaneous stone is removed, soil is cleaned, is broken into fritter;
2nd, Radix Codonopsis:Reed, section or cutting is run through after clean silt, is dried;
3rd, Flos Magnoliae:Net branch stalk impurity is picked, use is smashed to pieces;
4th, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, cut into slices, airing;
5th, Folium Mori:Impurity is picked, stranding is broken, winnows with a dustpan destemming, weeds out spare;
6th, Semen Cuscutae:Cross square-bottomed bamboo basket and remove impurity, clean, dry;
7th, Spica Prunellae:Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out;
8th, the Radix Angelicae Dahuricae:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after moistening, section Dry;
9th, Folium Eriobotryae:Fine hair is brushed away, is washed, slightly moistened, shredding is dried;
10th, Flos Lonicerae:Silt is weeded out, net impurity is picked;
11st, Radix Saposhnikoviae:Residual stem is removed, is soaked in water, pulled out, run through section, dry;
12nd, Rhizoma Ligustici:Crude drug is taken, impurity is removed, size stepping, wash quickly are net, run through, and cut into slices, dry;
13rd, Herba Centipedae:Net impurity is picked, cutting is dried;
14th, Semen Sojae Preparatum:Original is used as medicine;
15th, Stigma Croci:Net impurity is picked, stem and leaf, base of a fruit head is removed, is dried;
16th, Folium Perillae:Net impurity is picked, is dried;
17th, Herba Houttuyniae:Impurity is removed, undesirable root is removed, cutting is cleaned, is dried;
18th, Radix Platycodoniss:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dry;
19th, Fructus Gardeniae:Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends;
20th, Radix Scutellariae:Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiled water with cold water and pull out, cut into slices, dry;
21st, Herba Lophatheri:Impurity and root is picked, cutting is dried;
22nd, Fructus Forsythiae:Net impurity is picked, stranding is opened, except discarding stalk;
23rd, Radix Adenophorae:Fibrous root is removed, is cleaned, is scraped off rough bark, dried;
24th, Herba Menthae:Pick net impurity, remove undesirable root, first by leaf tremble lower separately put, stem is sprayed clear water then, rear cutting is run through, is shone Dry, then with leaf and even;
25th, Herba Epimedii:Net impurity is picked, destemming, shredding weeds out chip;
26th, the Rhizoma Atractylodis Macrocephalae:Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dry;
27th, Radix Ophiopogonis:Net impurity is picked, is soaked in water, pulled out, after running through, pump the heart, then cleaned and dry;
28th, Cortex Mori:Grey bits are brushed away, is cleaned, is run through rear shredding, dry;
29th, Fructus Arctii:Impurity is picked, spare is weeded out;
30th, Herba Ephedrae:Impurity is picked, most woody stems and undesirable root is removed, is washed, cutting after micro- profit is dried;
31st, Semen Armeniacae Amarum:Net impurity is picked, is put in boiling water and is slightly boiled, skin microcreping of waiting rises and pulls out, in leaching cold water, sloughed kind of a skin, dry, winnowed with a dustpan net.
2nd, prepare
1st, by processing after Gypsum Fibrosum, Radix Codonopsis, Flos Magnoliae, Radix Glycyrrhizae, Folium Mori, Semen Cuscutae, Spica Prunellae, the Radix Angelicae Dahuricae, Folium Eriobotryae, Flos Lonicerae, anti- Wind, Rhizoma Ligustici, Herba Centipedae, Semen Sojae Preparatum, Stigma Croci, Folium Perillae, Herba Houttuyniae, Radix Platycodoniss, Fructus Gardeniae, Radix Scutellariae, Herba Lophatheri, Fructus Forsythiae, Nansha Ginseng, Herba Menthae, Herba Epimedii, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, Cortex Mori, Fructus Arctii, Herba Ephedrae, Semen Armeniacae Amarum are put in decocting container, add water 8 times for the first time Amount, after soaking 100 minutes, fries by intense fire to boil and rises, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, will be for the first time Decoction liquor is poured in container;
2nd, the medicinal residues of filtration are added 6 times of amounts, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.
In prescription, Flos Magnoliae has wind-dispelling, sensible, controls nasal sinusitis, and obstructed function of having a stuffy nose is monarch drug;Folium Eriobotryae lung heat clearing stomach function regulating, sending down the abnormal ascending QI Expectorant;Radix Platycodoniss have out lung qi dispersing gas, and the function of eliminating the phlegm evacuation of pus, the two are ministerial drug, and three taste medicines play wind-dispelling jointly, sensible, open lung qi dispersing gas, Lung heat clearing stomach function regulating, the effect of lowering the adverse-rising QI to resolve phlegm, treatment chronic rhinitiss effect comprehensively, and with expelling pathogenic wind and restoring the functions of orifices in face, open lung qi dispersing gas, and lowering the adverse-rising QI to resolve phlegm is Master can be effected a permanent cure, and Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription, solve the function of poison of drug and alimentary toxicosis for adjuvant drug, the Rhizoma Atractylodis Macrocephalae Have a spleen reinforcing, stomach reinforcing, dampness, and in function for making medicine, be to take stopgap measures with remaining all medicines.
Medicine of the present invention has expelling pathogenic wind and restoring the functions of orifices in face, opens lung qi dispersing gas, lowering the adverse-rising QI to resolve phlegm, and middle emergency, and lung moistening is detoxified, spleen reinforcing stomach reinforcing Function, for treating chronic rhinitiss, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, and these test examples include this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0 2.5kg of body weight are divided to two groups, 15 per group, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept chronic rhinitiss out-patient totally 27 for medical treatment.
2nd, diagnostic criteria
Classical symptom is that many nasal mucus of pus tears mostly are purulence or viscous purulence, yellow or yellow green, and how much indefinite measure, and flows to throat more It is more common in odontogenic maxillary sinusitis in portion, there is stink one side person.Nasal obstruction:Weight, how because of nasal decongestion swelling and secretions Caused by increasing, nasal obstruction can often cause temporary olfactory disorder.Headache:Dull pain or head sense of heaviness are often shown as, daytime is heavy, night Gently.As pus tears flow into pharyngeal and long-term use mouth breathing, chronic pharyngitiss symptom, such as abundant expectoration, foreign body sensation or dry pharynx pain etc. is often accompanied by. If affecting pharyngotympanic tube, can also there are the symptoms such as tinnitus, deafness.
3rd, Therapeutic Method
From above-mentioned medicament, take to patient, each take 1 dose, early daily, evening respectively takes 1 time, is within 7 days a course for the treatment of, continuously takes With 3 courses for the treatment of.
4th, efficacy assessment standard
Effective:Chronic rhinitiss symptom disappears, and body constitution recovers normal, recovery from illness;
Take a turn for the better:Patient has a stuffy nose, and pus tears, the symptom mitigation of headache, chronic rhinitiss symptom are clearly better, and body constitution is progressively recovered;
Invalid:Improvement standard person is not reached.
5th, therapeutic outcome(See the table below)
In above-mentioned treatment, with Drug therapy chronic rhinitiss patient of the present invention 27, as a result effective 22, obvious effective rate is 81.48%, take a turn for the better 3, improvement rate is 11.11%, and invalid 2, total effective rate is 92.59%.

Claims (3)

1. a kind of medicine for treating chronic rhinitiss, it is characterised in that:It is made up of the crude drug in following weight range:
10-20 gram of Gypsum Fibrosum, 5-15 gram of Radix Codonopsis, 10-20 gram of Flos Magnoliae, 7-12 gram of Radix Glycyrrhizae, 5-15 gram of Folium Mori, 10-20 gram of Semen Cuscutae, summer 10-20 gram of hay, 10-15 gram of the Radix Angelicae Dahuricae, 10-20 gram of Folium Eriobotryae, 5-15 gram of Flos Lonicerae, 5-15 gram of Radix Saposhnikoviae, 5-15 gram of Rhizoma Ligustici, goose is not 5-15 gram of food grass, 10-20 gram of Semen Sojae Preparatum, 5-10 gram of Stigma Croci, 5-15 gram of Folium Perillae, 10-20 gram of Herba Houttuyniae, 5-15 gram of Radix Platycodoniss, 10-20 gram of Fructus Gardeniae, 5-15 gram of Radix Scutellariae, 5-15 gram of Herba Lophatheri, 5-15 gram of Fructus Forsythiae, 10-20 gram of Radix Adenophorae, 5-15 gram of Herba Menthae, excessive sheep 10-15 gram of the leaves of pulse plants, 5-15 gram of the Rhizoma Atractylodis Macrocephalae, 5-15 gram of Radix Ophiopogonis, 10-15 gram of Cortex Mori, 5-15 gram of Fructus Arctii, 3-9 gram of Herba Ephedrae, Semen Armeniacae Amarum 10- 15 grams.
2. medicine according to claim 1, the consumption of wherein each crude drug is:
15 grams of Gypsum Fibrosum, 10 grams of Radix Codonopsis, 15 grams of Flos Magnoliae, 9 grams of Radix Glycyrrhizae, 10 grams of Folium Mori, 15 grams of Semen Cuscutae, 15 grams of Spica Prunellae, the Radix Angelicae Dahuricae 12 Gram, 15 grams of Folium Eriobotryae, 10 grams of Flos Lonicerae, 10 grams of Radix Saposhnikoviae, 10 grams of Rhizoma Ligustici, 10 grams of Herba Centipedae, 15 grams of Semen Sojae Preparatum, 8 grams of Stigma Croci, 10 grams of Folium Perillae, 15 grams of Herba Houttuyniae, 10 grams of Radix Platycodoniss, 15 grams of Fructus Gardeniae, 10 grams of Radix Scutellariae, 10 grams of Herba Lophatheri, 10 grams of Fructus Forsythiae, Radix Adenophorae 15 Gram, 10 grams of Herba Menthae, 12 grams of Herba Epimedii, 10 grams of the Rhizoma Atractylodis Macrocephalae, 10 grams of Radix Ophiopogonis, 12 grams of Cortex Mori, 10 grams of Fructus Arctii, 6 grams of Herba Ephedrae, Semen Armeniacae Amarum 12 Gram.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Gypsum Fibrosum:Miscellaneous stone is removed, soil is cleaned, is broken into fritter;
(2)Radix Codonopsis:Reed, section or cutting is run through after clean silt, is dried;
(3)Flos Magnoliae:Net branch stalk impurity is picked, use is smashed to pieces;
(4)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, cut into slices, airing;
(5)Folium Mori:Impurity is picked, stranding is broken, winnows with a dustpan destemming, weeds out spare;
(6)Semen Cuscutae:Cross square-bottomed bamboo basket and remove impurity, clean, dry;
(7)Spica Prunellae:Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out;
(8)The Radix Angelicae Dahuricae:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after moistening, cut Piece is dried;
(9)Folium Eriobotryae:Fine hair is brushed away, is washed, slightly moistened, shredding is dried;
(10)Flos Lonicerae:Silt is weeded out, net impurity is picked;
(11)Radix Saposhnikoviae:Residual stem is removed, is soaked in water, pulled out, run through section, dry;
(12)Rhizoma Ligustici:Crude drug is taken, impurity is removed, size stepping, wash quickly are net, run through, and cut into slices, dry;
(13)Herba Centipedae:Net impurity is picked, cutting is dried;
(14)Semen Sojae Preparatum:Original is used as medicine;
(15)Stigma Croci:Net impurity is picked, stem and leaf, base of a fruit head is removed, is dried;
(16)Folium Perillae:Net impurity is picked, is dried;
(17)Herba Houttuyniae:Impurity is removed, undesirable root is removed, cutting is cleaned, is dried;
(18)Radix Platycodoniss:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dry;
(19)Fructus Gardeniae:Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends;
(20)Radix Scutellariae:Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiled water with cold water and pull out, cut into slices, dry;
(21)Herba Lophatheri:Impurity and root is picked, cutting is dried;
(22)Fructus Forsythiae:Net impurity is picked, stranding is opened, except discarding stalk;
(23)Radix Adenophorae:Fibrous root is removed, is cleaned, is scraped off rough bark, dried;
(24)Herba Menthae:Pick net impurity, remove undesirable root, first by leaf tremble lower separately put, stem is sprayed clear water then, rear cutting is run through, is shone Dry, then with leaf and even;
(25)Herba Epimedii:Net impurity is picked, destemming, shredding weeds out chip;
(26)The Rhizoma Atractylodis Macrocephalae:Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dry;
(27)Radix Ophiopogonis:Net impurity is picked, is soaked in water, pulled out, after running through, pump the heart, then cleaned and dry;
(28)Cortex Mori:Grey bits are brushed away, is cleaned, is run through rear shredding, dry;
(29)Fructus Arctii:Impurity is picked, spare is weeded out;
(30)Herba Ephedrae:Impurity is picked, most woody stems and undesirable root is removed, is washed, cutting after micro- profit is dried;
(31)Semen Armeniacae Amarum:Net impurity is picked, is put in boiling water and is slightly boiled, skin microcreping of waiting rises and pulls out, in leaching cold water, sloughed kind of a skin, dry, winnow with a dustpan Only;
(Two)Prepare
(1)Gypsum Fibrosum, Radix Codonopsis, Flos Magnoliae, Radix Glycyrrhizae, Folium Mori, Semen Cuscutae, Spica Prunellae, the Radix Angelicae Dahuricae, Folium Eriobotryae, Flos Lonicerae after by processing, anti- Wind, Rhizoma Ligustici, Herba Centipedae, Semen Sojae Preparatum, Stigma Croci, Folium Perillae, Herba Houttuyniae, Radix Platycodoniss, Fructus Gardeniae, Radix Scutellariae, Herba Lophatheri, Fructus Forsythiae, Nansha Ginseng, Herba Menthae, Herba Epimedii, the Rhizoma Atractylodis Macrocephalae, Radix Ophiopogonis, Cortex Mori, Fructus Arctii, Herba Ephedrae, Semen Armeniacae Amarum are put in decocting container, are added water 8 times and are measured, immersion After 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is fallen Enter in container;
(2)The medicinal residues of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and is taken.
CN201611113567.5A 2016-12-07 2016-12-07 A kind of treat medicine of chronic rhinitiss and preparation method thereof Withdrawn CN106492033A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169784A (en) * 2013-03-02 2013-06-26 赵明叶 Traditional Chinese medicine for treating rhinitis
CN104474174A (en) * 2014-11-27 2015-04-01 李坤 Medicine for treating rhinitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169784A (en) * 2013-03-02 2013-06-26 赵明叶 Traditional Chinese medicine for treating rhinitis
CN104474174A (en) * 2014-11-27 2015-04-01 李坤 Medicine for treating rhinitis and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张芯诚等: "鼻炎平治疗慢性鼻炎110例疗效观察", 《新中医》 *

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