CN106491889A - A kind of Chinese medicine composition for treating the change of cervical erosion sample and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating the change of cervical erosion sample and preparation method thereof Download PDF

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Publication number
CN106491889A
CN106491889A CN201611164074.4A CN201611164074A CN106491889A CN 106491889 A CN106491889 A CN 106491889A CN 201611164074 A CN201611164074 A CN 201611164074A CN 106491889 A CN106491889 A CN 106491889A
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cervical erosion
chinese medicine
medicine composition
selfheal
erosion sample
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朱秀玲
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HUOSHAN COUNTY HOSPITAL OF CHINESE MEDICINE
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HUOSHAN COUNTY HOSPITAL OF CHINESE MEDICINE
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Publication of CN106491889A publication Critical patent/CN106491889A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
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  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
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Abstract

The invention discloses a kind of Chinese medicine composition for treating the change of cervical erosion sample, is made up of following bulk drugs, the weight portion of each component is：Gypsum 8 10, borax 46, borneol 23, carbonized hair 68, dragon's blood 68, frankincense 35, myrrh 35, selfheal 15 20.The Chinese medicine composition that the treatment cervical erosion sample of the present invention changes, plays the integrally-regulated advantage of herbal mixture, can effectively play synergy, the effect of playing clearing heat and promoting diuresis, putrefaction-removing granulation-promoting, cures mainly cervical erosion sample and changes sequelae, good effect, instant effect, expense are low, without any side effects.

Description

A kind of Chinese medicine composition for treating the change of cervical erosion sample and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating the change of cervical erosion sample and its preparation Method.
Background technology
Cervical erosion is the modal pathology form of cervicitis, is modal one kind in gynecological disease. its harmfulness can To affect pregnancy, cause to miscarry, even result in cervical carcinogenesis etc..The symptom of cervical erosion:Leucorrhea increasing, itching of vulva pain, lower abdomen And it is waist and sacrum pain, frequent micturition or dysuria, infertile.As the symptom of cervical erosion is not substantially so there is a lot of people to ignore it Presence.For the treatment method of cervical erosion has a lot, moderate, moderate and severe cervical can adopt physical method, but thing Reason treatment is larger to the injury of patient.It is not fine more than the general effect of western medicine, and symptom in short-term can only be treated, it is impossible to root Control, large side effects.
The present invention provides a kind of pure Chinese medicine prescription, and treatment cervical erosion sample changes, and effect is good, and instant effect, expense are low, substantially Without toxic and side effect.
Content of the invention
The invention discloses a kind of treat the Chinese medicine composition that cervical erosion sample changes, this Chinese medicine composition has heat-clearing profit The effect of wet, putrefaction-removing granulation-promoting, treatment cervical erosion sample, change, good effect, instant effect.
The technical solution used in the present invention is as follows：
A kind of Chinese medicine composition for treating the change of cervical erosion sample, it is characterised in that be made up of following bulk drugs, the weight of each component Measuring part is：Gypsum 8-10, borax 4-6, borneol 2-3, carbonized hair 6-8, dragon's blood 6-8, frankincense 3-5, myrrh 3-5, selfheal 15- 20.
The Chinese medicine composition that described treatment cervical erosion sample changes, it is characterised in that be made up of following bulk drugs, each group Point weight portion be：Gypsum 9, borax 5, borneol 3, carbonized hair 7, dragon's blood 7, frankincense 4, myrrh 4, selfheal 18.
The preparation method of the Chinese medicine composition that described treatment cervical erosion sample changes, it is characterised in that including following step Suddenly：
（1）Each component raw material is weighed by formula rate；
（2）Selfheal in formula is crushed, then crosses 60 mesh sieves, add in meal meal quality 4-6% honey, 1% Fructus hordei germinatus powder, 1% black bean powder, 150% pure water, prepare culture medium, and in 121 DEG C of 20 min that sterilize, after cooling, by 1% Inoculum concentration inoculating lactobacillus acidophilus, press 2% inoculum concentration inoculation yeast, temperature be 35-36 DEG C under conditions of, ferment 24-36h, After fermentation ends, dry under the conditions of 50-55 DEG C, obtain selfheal yeast powder；
（3）To step（2）The 8-10 times of alcohol reflux that measures is added to extract in the selfheal yeast powder for obtaining 2-3 time, each 3-4h is closed And filtrate, obtaining the extract that ferments, decompression recycling ethanol is to must ferment extraction thick paste without alcohol taste；
（4）Alcohol reflux extract after the dregs of a decoction and formula in the mixing of remaining bulk drug, then plus the 10-15 times of decocting that measures boils 2- 3 times, each 1-1.5h is filtered, merging filtrate；
（5）By step（3）The medicinal extract of acquisition is added to step（4）Filtrate in, be sufficiently mixed uniform, obtain leaching liquor.
Usage and dosage：A day three times, first clean affected part every time with warm water, then rinsed with 30-50ml leaching liquors again and suffered from Place, general 6-7 days is a course for the treatment of.
Beneficial effect
The Chinese medicine composition that the treatment cervical erosion sample of the present invention changes, plays the integrally-regulated advantage of herbal mixture, can be effective Synergy is played, the effect of play heat-clearing, antibacterial, blood stasis removing analgesic, clearing damp, myogenic sore, is cured mainly after cervical erosion sample changes Disease is lost, good effect, instant effect, expense are low, without any side effects.Through the treatment of 180 patients, total effective rate is 94.6%, effectively or uterine neck I-III degree erosion sample can be cured change, improve minimal invasive treatment.Effective 82.2%, effective 12.4%, nothing Effect 5.4%.
Specific embodiment
A kind of Chinese medicine composition for treating the change of cervical erosion sample, is made up of following bulk drugs, the weight of each component（g） For：
Gypsum 9, borax 5, borneol 3, carbonized hair 7, dragon's blood 7, frankincense 4, myrrh 4, selfheal 18.
Preparation method：
（1）Each component raw material is weighed by formula rate；
（2）Selfheal in formula is crushed, then crosses 60 mesh sieves, add in meal meal quality 4-6% honey, 1% Fructus hordei germinatus powder, 1% black bean powder, 150% pure water, prepare culture medium, and in 121 DEG C of 20 min that sterilize, after cooling, by 1% Inoculum concentration inoculating lactobacillus acidophilus, press 2% inoculum concentration inoculation yeast, temperature be 35-36 DEG C under conditions of, ferment 24-36h, After fermentation ends, dry under the conditions of 50-55 DEG C, obtain selfheal yeast powder；
（3）To step（2）The 8-10 times of alcohol reflux that measures is added to extract in the selfheal yeast powder for obtaining 2-3 time, each 3-4h is closed And filtrate, obtaining the extract that ferments, decompression recycling ethanol is to must ferment extraction thick paste without alcohol taste；
（4）Alcohol reflux extract after the dregs of a decoction and formula in the mixing of remaining bulk drug, then plus the 10-15 times of decocting that measures boils 2- 3 times, each 1-1.5h is filtered, merging filtrate；
（5）By step（3）The medicinal extract of acquisition is added to step（4）Filtrate in, be sufficiently mixed uniform, obtain leaching liquor.
Usage and dosage：A day three times, first clean affected part every time with warm water, then rinsed with 30-50ml leaching liquors again and suffered from Place, general 6-7 days is a course for the treatment of.
Model case
1. patient Song：Leucorrhea increasing remaining, diagnosis in a week：Cervicitis（Uterine neck III degree is rotten to the corn）, give the prescription vagina drug applying one week After fully recover, follow-up April is without recurrence.
2. patient Zhang：Leucorrhea increasing color is yellow more than 2 months, diagnosis：Cervicitis（Uterine neck I degree is rotten to the corn）, give on the prescription vagina Medicine was fully recovered after 1 week, and follow-up 2 months is without without recurrence.
3. patient Wang：Leucorrhea increasing color is yellow more than 1 year, diagnosis：Cervicitis (uterine neck II-III degree is rotten to the corn), gives the prescription cloudy Road is clearly better after adding medicine to 2 weeks, and uterine neck I degree is rotten to the corn.Follow-up does not increase for 2 months.
4th, patient Sun：Pruritus vulvue, leucorrhea increasing more than 1 year, diagnose repeatedly：Vaginitis, cervicitis（Uterine neck III degree is rotten Rotten）, give the prescription vagina drug applying to be clearly better after one week, uterine neck I degree is rotten to the corn, and follow-up does not increase for 2 months, continues 2 treatments of medication afterwards Journey, recovery from illness, follow-up half a year is without recurrence.

Claims (3)

1. a kind of treat cervical erosion sample change Chinese medicine composition, it is characterised in that be made up of following bulk drugs, each component Weight portion is：Gypsum 8-10, borax 4-6, borneol 2-3, carbonized hair 6-8, dragon's blood 6-8, frankincense 3-5, myrrh 3-5, selfheal 15- 20.
2. the Chinese medicine composition that treatment cervical erosion sample according to claim 1 changes, it is characterised in that by following raw materials according Medicine is constituted, and the weight portion of each component is：Gypsum 9, borax 5, borneol 3, carbonized hair 7, dragon's blood 7, frankincense 4, myrrh 4, selfheal 17.
3. the preparation method of the Chinese medicine composition that treatment cervical erosion sample as claimed in claim 1 changes, it is characterised in that bag Include following steps：
（1）Each component raw material is weighed by formula rate；
（2）Selfheal in formula is crushed, then crosses 60 mesh sieves, add in meal meal quality 4-6% honey, 1% Fructus hordei germinatus powder, 1% black bean powder, 150% pure water, prepare culture medium, and in 121 DEG C of 20 min that sterilize, after cooling, by 1% Inoculum concentration inoculating lactobacillus acidophilus, press 2% inoculum concentration inoculation yeast, temperature be 35-36 DEG C under conditions of, ferment 24-36h, After fermentation ends, dry under the conditions of 50-55 DEG C, obtain selfheal yeast powder；
（3）To step（2）The 8-10 times of alcohol reflux that measures is added to extract in the selfheal yeast powder for obtaining 2-3 time, each 3-4h is closed And filtrate, obtaining the extract that ferments, decompression recycling ethanol is to must ferment extraction thick paste without alcohol taste；
（4）Alcohol reflux extract after the dregs of a decoction and formula in the mixing of remaining bulk drug, then plus the 10-15 times of decocting that measures boils 2- 3 times, each 1-1.5h is filtered, merging filtrate；
（5）By step（3）The thick paste of acquisition is added to step（4）Filtrate in, be sufficiently mixed uniform.
CN201611164074.4A 2016-12-16 2016-12-16 A kind of Chinese medicine composition for treating the change of cervical erosion sample and preparation method thereof Pending CN106491889A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109157594A (en) * 2018-11-26 2019-01-08 西安百世惠众生物工程有限公司 A kind of pure Chinese medicinal preparation and preparation method thereof for treating fibroid and cervical erosion

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109157594A (en) * 2018-11-26 2019-01-08 西安百世惠众生物工程有限公司 A kind of pure Chinese medicinal preparation and preparation method thereof for treating fibroid and cervical erosion

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Application publication date: 20170315