CN106491793A - A kind of treat medicine of appendicitis and preparation method thereof - Google Patents
A kind of treat medicine of appendicitis and preparation method thereof Download PDFInfo
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Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/355—Lonicera (honeysuckle)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a kind of treat medicine of appendicitis and preparation method thereof, which is mainly prepared from according to a certain weight ratio by honeysuckle, the coptis, the root of large-flowered skullcap, golden cypress, cape jasmine, Ligusticum wallichii, the capsule of weeping forsythia, medicine of the present invention has clearing heat and detoxicating, excess fire is rushed down, except damp and hot, replenishing and activating blood, the function of promote breath and open depression, for treating appendicitis instant effect, good effect does not recur.
Description
Technical field
The present invention relates to a kind of treat medicine of appendicitis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Appendicitis is because of many factors and the inflammatory that formed changes, and is surgical common disease, with the most common, the Nan Xingduo of youth
In women.The traditional Chinese medical science then thinks that appendicitis and stagnation of QI-blood, endoretention of damp heat are accumulated with pass in heat toxin.Due to western medicine large side effects,
Therefore there is great demand to the Chinese medicine of effectively treatment appendicitis in people, up to now, it has not been found that with regard to this
Bright relevant report.
Content of the invention
The present inventor have found effectively treatment appendix finally according to the research and the checking repeatedly of clinical testing of theory of traditional Chinese medical science
Scorching medicine, so that complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment appendicitis.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select honeysuckle, the coptis, the root of large-flowered skullcap, golden cypress, cape jasmine, Ligusticum wallichii, the capsule of weeping forsythia, rheum officinale, angelica medicament to enter
Prepared by row combination, cause each efficacy of drugs to produce synergy these drug regimens such that it is able to effectively treatment appendicitis.
Wherein it is because that its nature and flavor is sweet from honeysuckle, trembles with fear, enter lung, stomach, have heat-clearing, the function of removing toxic substances to control warm disease heating, heat toxin blood
Dysentery, large carbuncle, pyogenic infections, scrofula, anal fistula.It is because that its nature and flavor is bitter from the coptis, trembles with fear, enter the heart, liver, stomach, large intestine channel has purging intense heat, dry
Wet, removing toxic substances, the function of desinsection, row heat toxin, typhoid fever when controlling, heat is contained vexed, and feeling of fullness is vomitted inverse, bacillary dysentery, and heat rushes down stomachache, pulmonary tuberculosis, tell,
Nosebleed, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, abscess of throat, pinkeye, aphtha, skin sore, eczema, the burning hot wound of soup.Choosing
It is because that its nature and flavor is bitter with the root of large-flowered skullcap, trembles with fear, enter the heart, lung, courage, large intestine channel have and rush down excess fire, except damp and hot, stop blooding, antiabortive function is controlled
High fever polydipsia, cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea are told, are defeated in battle, collapse, are leaked, red eye, swell pain, fetal irritability, carbuncle swells furunculosis.
It is because that its nature and flavor is bitter from golden cypress, trembles with fear, enter lung, stomach, kidney channel, have nourishing Yin and falling fire, the function of moisturize laxation to control dysphoria with smothery sensation and quench one's thirst,
Hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.It is because that its nature and flavor is bitter from cape jasmine, trembles with fear, enter the heart, liver, lung, stomach
Through, there are heat-clearing, purging intense heat, the function of cool blood to control pyreticosis restlessness of asrhenia type and insomnia, jaundice, gonorrhoea are quenched one's thirst, hot eyes, pharyngalgia, spit blood, bleeding from five sense organs or subcutaneous tissue,
Bloody flux, hematuria, pathopyretic ulcer are sprained and are swollen and ache.It is because that its nature and flavor is pungent from Ligusticum wallichii, temperature, enter liver, gallbladder channel have promote breath and open depression, dispel
Wind-dryness is wet, the function of promoting blood circulation and stopping pain, controls air-cooled headache rotation and swoons, and hypochondriac pain abdomen aches, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block
Bitterly, ulcer sores.It is because that its nature and flavor is bitter from the capsule of weeping forsythia, cool, enter the heart, liver, gallbladder channel have heat-clearing, detoxifies, dissipating bind, the work(of detumescence
Can, control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.It is because that its nature and flavor is bitter, cold from rheum officinale, enters stomach, big
, there is the poison that purges heat in intestines, liver footpath, and break and stagnate, and the function of row hemostasis controls real heat constipation, and delirious speech is gone mad, dyspepsia feeling of fullness, and dysentery is from the beginning of inner
Weight after urgency, stasis of blood menopause closes, and lump in the abdomen is gathered, when the hot epidemic disease of row, sudden and violent swelling ophthalmalgia spits blood, and bleeding from five sense organs or subcutaneous tissue, yang jaundice, oedema, stranguria with turbid discharge are urinated red, large carbuncle
Pyogenic infections, furunculosis, burn.Its nature and flavor sweet, acrid, warm is because from Radix Angelicae Sinensis, enter the heart, liver, the spleen channel have replenishing and activating blood, menstruation regulating to stop
Bitterly, the function of moisturize laxation, controls irregular menstruation, and Amenorrhea is suffered from abdominal pain, and lump in the abdomen knot is poly-, and uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness are difficult
Just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.
Specific embodiment
The drug dose of instant component is also that inventor is drawn through groping in a large number to summarize, and the consumption of each component is following heavy
All there is in the range of amount preferable curative effect：
25-35 gram of honeysuckle, 20-30 gram of the coptis, 20-30 gram of the root of large-flowered skullcap, 20-30 gram of golden cypress, 17-21 gram of cape jasmine, Ligusticum wallichii 17-21
Gram, 17-21 gram of the capsule of weeping forsythia, 10-15 gram of rheum officinale, 4-8 gram of Radix Angelicae Sinensis.
Preferably：
30 grams of honeysuckle, 25 grams of the coptis, 25 grams of the root of large-flowered skullcap, 25 grams of golden cypress, 19 grams of cape jasmine, 19 grams of Ligusticum wallichii, 19 grams of the capsule of weeping forsythia, rheum officinale l3
Gram, 6 grams of Radix Angelicae Sinensis.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, honeysuckle：Silt is weeded out, net impurity is picked；
2nd, the coptis：Impurity is picked, silt particle is cleaned, is run through, cut into slices, dry in the shade；
3rd, the root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dry；
4th, golden cypress：Impurity is picked, is washed, pulled out, run through, cut into slices or chopping, dry；
5th, cape jasmine：Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends；
6th, Ligusticum wallichii：Impurity is picked, is separated large and small, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried；
7th, the capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
8th, rheum officinale：Net impurity is picked, size stepping, vexed profit are uniform to inside and outside humidity, cut into slices or are cut into small pieces, dry；
9th, Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried.
2nd, prepare
1st, the honeysuckle of the weight, the coptis, the root of large-flowered skullcap, golden cypress, cape jasmine, Ligusticum wallichii, the capsule of weeping forsythia, rheum officinale, Radix Angelicae Sinensis are put into decocting container
Interior, add water for the first time 6 times and measure, after soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain for the first time
Decoction liquor, first time decoction liquor is poured in container；
2nd, the dregs of a decoction of filtration are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
3rd, will decoction liquor mixing and stirring twice, be divided into 2 doses and take.
There is heat-clearing with honeysuckle in prescription, the function of removing toxic substances is monarch drug in a prescription；The root of large-flowered skullcap rushes down excess fire, except damp and hot；Radix Angelicae Sinensis is enriched blood work
Blood, menstruction regulating and pain relieving, the function of moisturize laxation, the two is ministerial drug, and three taste medicines play clearing heat and detoxicating jointly, rush down excess fire, except damp and hot, mend
Blood is invigorated blood circulation, the effect of moisturize laxation, and treatment appendicitis effect comprehensively, and with clearing heat and detoxicating, rushes down excess fire, except damp and hot, replenishing and activating blood
Based on can effect a permanent cure, the coptis has a purging intense heat, eliminating dampness, removing toxic substances, and the function of desinsection is adjutant, and Ligusticum wallichii has promote breath and open depression, the work(for dispelling pathogenic wind and remove dampness
Can be for making medicine, remaining all medicines are to take stopgap measures.
Medicine of the present invention has clearing heat and detoxicating, rushes down excess fire, and except damp and hot, replenishing and activating blood, the function of promote breath and open depression, for treating
Appendicitis, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, and these test examples include this
The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention：
Rabbit 30 is taken, male and female dual-purpose, 2.0 2.5kg of body weight are divided to two groups, 15 per group, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage
Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad
Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept appendicitis out-patient totally 33 for medical treatment.
2nd, diagnostic criteria
Classical symptom is stomachache, reflectivity gastrospasm, indigestion, fever, tension of abdominal muscle, abdominal tenderness etc..
3rd, treatment method
From above-mentioned medicament, take to patient, each take 1 dose, early daily, evening respectively takes 1 time, is within 7 days a course for the treatment of, continuously takes
With 2 courses for the treatment of.
4th, efficacy assessment standard
Effective：Appendicitis symptom disappears, and physique recovers normal, recovery from illness；
Take a turn for the better：Patient suffers from abdominal pain, indigestion, and the phenomenon such as gastrospasm tension of abdominal muscle mitigates, and appendicitis symptom is clearly better, physique by
Step is recovered；
Invalid：Improvement standard person is not reached.
5th, treatment results（See the table below）
In above-mentioned treatment, with drug therapy Appendicitis Patients of the present invention 33, as a result effective 29, obvious effective rate is 87.88%,
Take a turn for the better 3, improvement rate is 9.09%, and invalid 1, total effective rate is 96.97%.
Claims (3)
1. a kind of medicine for treating appendicitis, it is characterised in that：It is made up of the bulk drug in following weight range：
25-35 gram of honeysuckle, 20-30 gram of the coptis, 20-30 gram of the root of large-flowered skullcap, 20-30 gram of golden cypress, 17-21 gram of cape jasmine, Ligusticum wallichii 17-21
Gram, 17-21 gram of the capsule of weeping forsythia, 10-15 gram of rheum officinale, 4-8 gram of Radix Angelicae Sinensis.
2. medicine according to claim 1, the consumption of wherein each bulk drug is：
30 grams of honeysuckle, 25 grams of the coptis, 25 grams of the root of large-flowered skullcap, 25 grams of golden cypress, 19 grams of cape jasmine, 19 grams of Ligusticum wallichii, 19 grams of the capsule of weeping forsythia, rheum officinale l3
Gram, 6 grams of Radix Angelicae Sinensis.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Honeysuckle：Silt is weeded out, net impurity is picked；
（2）The coptis：Impurity is picked, silt particle is cleaned, is run through, cut into slices, dry in the shade；
（3）The root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dry；
（4）Golden cypress：Impurity is picked, is washed, pulled out, run through, cut into slices or chopping, dry；
（5）Cape jasmine：Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends；
（6）Ligusticum wallichii：Impurity is picked, is separated large and small, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried；
（7）The capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
（8）Rheum officinale：Net impurity is picked, size stepping, vexed profit are uniform to inside and outside humidity, cut into slices or are cut into small pieces, dry；
（9）Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
（Two）Prepare
（1）The honeysuckle of the weight, the coptis, the root of large-flowered skullcap, golden cypress, cape jasmine, Ligusticum wallichii, the capsule of weeping forsythia, rheum officinale, Radix Angelicae Sinensis are put into decocting container
Interior, add water 6 times and measure, after soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain decoction for the first time
Liquid, first time decoction liquor is poured in container；
（2）The dregs of a decoction of filtration are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；
（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 2 doses and is taken.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611145051.9A CN106491793A (en) | 2016-12-13 | 2016-12-13 | A kind of treat medicine of appendicitis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611145051.9A CN106491793A (en) | 2016-12-13 | 2016-12-13 | A kind of treat medicine of appendicitis and preparation method thereof |
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| CN201611145051.9A Withdrawn CN106491793A (en) | 2016-12-13 | 2016-12-13 | A kind of treat medicine of appendicitis and preparation method thereof |
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| Country | Link |
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2016
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Application publication date: 20170315 |