CN106491785A - Easypro mixture of stomach and preparation method thereof - Google Patents

Easypro mixture of stomach and preparation method thereof Download PDF

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Publication number
CN106491785A
CN106491785A CN201611257025.5A CN201611257025A CN106491785A CN 106491785 A CN106491785 A CN 106491785A CN 201611257025 A CN201611257025 A CN 201611257025A CN 106491785 A CN106491785 A CN 106491785A
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parts
radix
stomach
mixture
raw material
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王登华
焦玉峰
焦守正
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

Mixture and preparation method thereof the present invention relates to a kind of stomach relaxes, in terms of parts by weight, raw material composition is as follows:10 50 parts of Fructus Crataegi, 10 30 parts of the Radix Aucklandiae, 10 30 parts of Radix Glehniae, 6 12 parts of Radix Bupleuri, 6 20 parts of the Radix Paeoniae Alba, 6 12 parts of Fructus Aurantii, 6 12 parts of Radix Glycyrrhizae Preparata, 10 30 parts of Rhizoma Corydalis, 6 20 parts of Cortex Magnoliae Officinalis, 3 10 parts of Pericarpium Citri Reticulatae, 9 30 parts of Poria, 39 parts of Rhizoma Coptidis, 36 parts of Fructus Evodiae.The present invention solves the full pain of gastrointestinal account, and pareordia is burnt, general acid regurgitation water, noisy centrifugation, supports account back, and two coerce account pain, and the problem of inappetence, have functions that strengthening the spleen stopping leak, mind tranquilizing and the heart calming.Formula has no toxic side effect, the factor for affecting gastrointestinal function is nursed one's health comprehensively, so as to lift human body itself combined immune power, and by adjusting the microcirculation of gastrointestinal tract and surrounding organ, the natural division of gastrointestinal tract mucous cell is promoted more to newly arrive and reach the spontaneous recovery of inflammation, effect is more longlasting, and relapse rate is lower.

Description

Easypro mixture of stomach and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese medicine technology, is related to easypro mixture of a kind of stomach and preparation method thereof.
Background technology:
Doctor trained in Western medicine thinks to cause the common disease of stomachache to have:1. gastric ulcer:The pain of gastric ulcer patient with eat relevant, generally Once the sensation that stomach of eating has distending pain, stomachache in going up after meal at once, or there are Nausea and vomiting, food stagnation sense, the time of disease may Very long;Pain is regular, such as suffer from cold, angry, eaten irritable food after show effect.If women, also stand when and The characteristics of tired postemphasis, that, will consider gastroptosis.
2. duodenal ulcer:The patient of duodenal ulcer often occurs stomachache, or even midnight pain when starvation Wake up, eat something and can alleviate, often have acid regurgitation phenomenon.Pain is to the right in upper abdomen, has the rhythm and pace of moving things.
3. chronic gastritiss:The pain majority of chronic gastritiss is least rule, and its outbreak variable interval both may be by spirit Anxiety causes, it is also possible to relevant with dyspepsia.Show as glutted after meal or glutted all day, belch but not acid regurgitation, have no appetite, Body weight gradually mitigates, and complexion is slightly pale or burnt hair.
Clinical western medicine has omeprazole, ranitidine, sucralfate, motilium, amoxicillin, metronidazole to wait clinic Curative effect can be with, but high recurrence rate, or even long-term taking hepatorenal damage is obvious.
Content of the invention
Mixture and preparation method thereof it is an object of the invention to provide a kind of stomach relaxes, solves the full pain of gastrointestinal account, and pareordia is burnt Burn, account back is supportted in general acid regurgitation water, noisy centrifugation, two side of body accounts pains, and the problem of inappetence, with strengthening the spleen stopping leak, mind tranquilizing and the heart calming Effect.Formula has no toxic side effect, and the factor for affecting gastrointestinal function is nursed one's health comprehensively, comprehensively exempts from so as to lift human body itself Epidemic disease power, and by adjusting the microcirculation of gastrointestinal tract and surrounding organ, promote the natural division of gastrointestinal tract mucous cell more to newly arrive and reach Into the spontaneous recovery of inflammation, effect is more longlasting, and relapse rate is lower.
The easypro mixture for the treatment of stomach, in terms of parts by weight, raw material composition is as follows:
Fructus Crataegi 10-50 parts, Radix Aucklandiae 10-30 parts, Radix Glehniae 10-30 parts, Radix Bupleuri 6-12 parts, Radix Paeoniae Alba 6-20 parts, Fructus Aurantii 6-12 Part, Radix Glycyrrhizae Preparata 6-12 parts, Rhizoma Corydalis 10-30 parts, Cortex Magnoliae Officinalis 6-20 part, Pericarpium Citri Reticulatae 3-10 parts, Poria 9-30 parts, Rhizoma Coptidis 3-9 parts, Wu Zhu Cornel 3-6 parts.
Raw material first steeps 25-35 minutes with clear water, and then slow fire boils 25-30 minutes, pours out first time medicine juice, reheats water Boil 25-35 minutes, then go out medicine juice for the second time, two parts of medicine juice be combined make decoction or
Excipient is added to make the 4-6mm watered pills to -300 mesh of 120 mesh raw material micronizing.
Excipient is starch.
The preparation method of decoction is preferably as follows step:Raw material first steeps 30 minutes with clear water, and then slow fire boils 30 minutes, Go out first time medicine juice, reheat decocting in water and boil 30 minutes, then go out medicine juice for the second time, two parts of medicine juice are combined and make decoction.
Wherein, the drug action mechanism in the present invention is as follows:
Cortex Magnoliae Officinalis, Rhizoma Corydalis promoting flow of QI and blood relieve the pain, and disappear completely except account is monarch, and Radix Bupleuri, Fructus Aurantii, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata are minister depressed liver-energy dispersing and QI regulating Emergency relieves the pain and helps monarch to eliminate primary symptom, irritability adjust smooth, taste from and, Fructus Crataegi, Radix Aucklandiae digestion-promoting spleen-invigorating ascending gastric qi, Radix Glehniae is from clinic Know from experience mainly to the moon effect of lung stomach substantially, nourishing YIN and moistening the lung stomach clearing away heat and promoting production of body fluid, Pericarpium Citri Reticulatae disappear account preventing or arresting vomiting, qi-regulating appetizing, Poria diuretic Dehumidifying mind tranquilizing and the heart calming, strengthening the spleen stopping leak.Rhizoma Coptidis, Fructus Evodiae match cure mainly hot-tempered, incoordination between the liver and stomach and cause have a stomach-ache, noisy, general acid regurgitation Water, lets out clearly heart gastric heat, the effect of cool liver gallbladder.
Usage and dosage:In two times orally the morning and evening was each once, one after each meal in one day for decoction.The each 9g of the watered pill, takes 23 daily Secondary.
During medication, clothes raw food is avoided pungent.
Stomach of the present invention relaxes mixture and preparation method thereof for treating medicament of gastrointestinal and preparation method thereof.
Therapeutic outcome:
Clinical treatment of the present invention 100, complete cure rate 90%, remission rate 7% do not cure 3%.
Treatment standard:
Recovery from illness:Clinical symptoms all disappear, and barivm meal fluoroscopy (screem) or gastroscopy show without exception.
Take a turn for the better:Cardinal symptom substantially mitigates, and improvement in various degree occur in barivm meal fluoroscopy (screem) or gastroscopy.
Invalid:Cardinal symptom is not alleviated or occurs increasing in original degree in various degree.
It is exemplified below several model cases:
Case 1
Slowly certain, female, 53 years old, Yan Ya towns Shuan Quan people from villages
Gastralgia 10 days, because conflicting after anger with neighbours, starts to have a stomach-ache, and not account is not ached in belch pneumoperitoneum portion, after diet There is the vexed sense of painful abdominal mass, eat gastral cavilty portion sense of discomfort after raw food at ordinary times, two just adjust, and sleep can.Light red tongue tongue has petechia.
With stomach 3 doses of recoveries from illness of easypro mixture, pay a return visit after half a year and do not recur.
Case 2
Chen, man, 14 years old, student, Yan Ya towns Dong Bai valleys people from village
Gastralgia 8 months, often sense pain of gastric cavity is with nausea, bitter taste, afternoon 17:00-19:00 abdomen pain can increase, after having a meal Abdomen pain increases, at ordinary times easily acid regurgitation, centrifugation, abdominal distention, every time greedy cool after have a stomach-ache and increase, two just adjust, and appetite is poor, sleep can, light red tongue tongue Thick in vain, thready and stringy pulse moistens.
After taking easypro 6 doses of the mixture of stomach, pain of gastric cavity mitigates, and still has abdominal distention, bitter taste to subtract feelings, then after taking 9 doses, pain of gastric cavity is alleviated, food It is intended to take a turn for the better, body weight increases 2.5kg earlier above, reaches recovery from illness, pays a return visit after half a year and do not recur.
Case 3
Zhu, man, 63 years old, Yan Yazhujia families people from village
Gastralgia 5 years, often has erratic behavior abdomen to ache, at ordinary times implication weight, likes sweet food over 5 years, without hunger sensation, appetite can. Two just adjust, and light red tongue tongue is partially dry, and stringy pulse is long.
After taking easypro 3 doses of the mixture of stomach, during further consultation, have a stomach-ache alleviation, and implication mitigates again, gives the easypro mixture micronizing of stomach to 120 - 300 mesh of mesh adds excipient to make the 4-6mm watered pills, and each 9g is twice a day, bfore meals.During medication, avoid clothes raw food pungent, After taking one month, all diseases disappear, and reach recovery from illness.
It is below clinical comparison case summary:
2011-2016, clinical observation 100 in 5 years, gastroscope chronic gastritiss, Peptic Ulcers, wherein 50 are given Mono- group of bismuth potassium citrate 240mg+ amoxicillin 750mg+ metronidazole 400mg+ omeprazoles 20mg is given to take, two times a day (on Afternoon is each 1 time), 7-14 days be a course for the treatment of, after a course for the treatment of terminates, then individually take bismuth potassium citrate 6 weeks, dosage and administration with front Face is identical.Other 50 give Chinese medicine of the present invention and take, and most short takes 6 doses, and most long takes 4-8 weeks, by clinical observation Contrast, Western medicine relapse rate are of a relatively high, and cure rate is low, large side effects.
Compared with prior art, the invention has the advantages that:
The present invention solves the full pain of gastrointestinal account, and pareordia is burnt, general acid regurgitation water, noisy centrifugation, supports account back, two side of body accounts Pain, the problem of inappetence, have functions that strengthening the spleen stopping leak, mind tranquilizing and the heart calming.Doctor trained in Western medicine gastric ulcer, chronic gastritiss, duodenum are burst Infectionss, gastroptosis, atrophic gastritis.
The formula that the easypro mixture of stomach is adopted is without any side effects, and clinical efficacy is notable.To affect gastrointestinal function because Element is nursed one's health comprehensively, so as to lift human body itself combined immune power, and by adjusting the microcirculation of gastrointestinal tract and surrounding organ, The natural division of gastrointestinal tract mucous cell is promoted more to newly arrive and reach the spontaneous recovery of inflammation, effect is more longlasting, and relapse rate is lower, particularly For cureless patron, and the patient that there is irreversible external factor has good therapeutic effect.
Specific embodiment
With reference to embodiment, the present invention is further illustrated.
Embodiment 1
In terms of parts by weight, raw material composition is as follows:
20 parts of Fructus Crataegi, 15 parts of the Radix Aucklandiae, 15 parts of Radix Glehniae, 10 parts of Radix Bupleuri, 12 parts of the Radix Paeoniae Alba, 8 parts of Fructus Aurantii, 10 parts of Radix Glycyrrhizae Preparata prolong 20 parts of Rhizoma Corydalis, 12 parts of Cortex Magnoliae Officinalis, 5 parts of Pericarpium Citri Reticulatae, 22 parts of Poria, 7 parts of Rhizoma Coptidis, 5 parts of Fructus Evodiae.
Treatment stomach relaxes the preparation method of mixture, and raw material first steeps 30 minutes with clear water, and then slow fire boils 30 minutes, pours out the Medicine juice, reheats decocting in water and boils 30 minutes, then go out medicine juice for the second time, and two parts of medicine juice are combined and make decoction.
Embodiment 2
In terms of parts by weight, raw material composition is as follows:
10 parts of Fructus Crataegi, 30 parts of the Radix Aucklandiae, 30 parts of Radix Glehniae, 6 parts of Radix Bupleuri, 20 parts of the Radix Paeoniae Alba, 6 parts of Fructus Aurantii, 12 parts of Radix Glycyrrhizae Preparata, Rhizoma Corydalis 30 parts of rope, 6 parts of Cortex Magnoliae Officinalis, 10 parts of Pericarpium Citri Reticulatae, 30 parts of Poria, 3 parts of Rhizoma Coptidis, 3 parts of Fructus Evodiae.
Treatment stomach relaxes the preparation method of mixture, and raw material first steeps 30 minutes with clear water, and then slow fire boils 30 minutes, pours out the Medicine juice, reheats decocting in water and boils 30 minutes, then go out medicine juice for the second time, and two parts of medicine juice are combined and make decoction.
Embodiment 3
In terms of parts by weight, raw material composition is as follows:
50 parts of Fructus Crataegi, 10 parts of the Radix Aucklandiae, 10 parts of Radix Glehniae, 12 parts of Radix Bupleuri, 6 parts of the Radix Paeoniae Alba, 12 parts of Fructus Aurantii, 6 parts of Radix Glycyrrhizae Preparata, Rhizoma Corydalis 10 parts of rope, 20 parts of Cortex Magnoliae Officinalis, 3 parts of Pericarpium Citri Reticulatae, 9 parts of Poria, 9 parts of Rhizoma Coptidis, 6 parts of Fructus Evodiae.
Above-mentioned raw materials micronizing is added excipient to make 4 to 120 mesh, 300 mesh by the preparation method of the easypro mixture for the treatment of stomach The 6mm watered pills, 9g are every time, twice a day, bfore meals.During medication, clothes raw food is avoided pungent.
Excipient is starch.

Claims (3)

1. stomach relax mixture, it is characterised in that in terms of parts by weight, raw material composition as follows:
Fructus Crataegi 10-50 parts, Radix Aucklandiae 10-30 parts, Radix Glehniae 10-30 parts, Radix Bupleuri 6-12 parts, Radix Paeoniae Alba 6-20 parts, Fructus Aurantii 6-12 parts are processed Radix Glycyrrhizae 6-12 parts, Rhizoma Corydalis 10-30 parts, Cortex Magnoliae Officinalis 6-20 part, Pericarpium Citri Reticulatae 3-10 parts, Poria 9-30 parts, Rhizoma Coptidis 3-9 parts, Fructus Evodiae 3-6 Part.
2. the preparation method of the easypro mixture of stomach described in a kind of claim 1, it is characterised in that raw material is first divided with clear water bubble 25-35 Clock, then slow fire boil 25-30 minutes, pour out first time medicine juice, reheat decocting in water boiling 25-35 minutes, then second drug Juice, two parts of medicine juice be combined make decoction or
Excipient is added to make the 4-6mm watered pills to -300 mesh of 120 mesh raw material micronizing.
3. stomach according to claim 2 relax mixture preparation method, it is characterised in that excipient is starch.
CN201611257025.5A 2016-12-30 2016-12-30 Easypro mixture of stomach and preparation method thereof Pending CN106491785A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108837098A (en) * 2018-09-05 2018-11-20 李新江 Stomach jinx's Traditional Chinese medicine capsule preparation

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN108837098A (en) * 2018-09-05 2018-11-20 李新江 Stomach jinx's Traditional Chinese medicine capsule preparation

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Application publication date: 20170315