CN106491651B

CN106491651B - A kind of compound concocting method of pizzle

Info

Publication number: CN106491651B
Application number: CN201610916181.1A
Authority: CN
Inventors: 庞克坚; 吴志豪; 郭瑶
Original assignee: Hotan Uygur Pharmaceutical Ltd By Share Ltd
Current assignee: Hotan Uygur Pharmaceutical Ltd By Share Ltd
Priority date: 2016-10-20
Filing date: 2016-10-20
Publication date: 2019-04-26
Anticipated expiration: 2036-10-20
Also published as: CN106491651A

Abstract

The invention discloses a kind of compound concocting methods of pizzle, and described method includes following steps: Step 1: pretreatment of raw material；Step 2: ultrasonic vacuum impregnates；Step 3: freezing；Step 4: low-temperature vacuum microwave is dry；Step 5: crushing；Step 6: hot wind-it is infrared-microwave drying；Step 7: packaging.

Description

A kind of compound concocting method of pizzle

Technical field

The present invention relates to drug manufacture fields, and in particular to a kind of compound concocting method of pizzle.

Background technique

Pizzle is common Uygur's medicinal material, is bovid ox Bos taurus domesticus Gmelin or yak The drying penis of ox Bos grunniens Linnaeus, is recorded in " Drug Standard of Ministry of Public Health of the Peoples Republic of China Uygur Medicine fascicle " (1999), there is kidney tonifying warm stomach, the effect of hernia is controlled in establishing-Yang.For lumbago due to the kidney deficiency, cold stomachache, sexual hypoesthesia and The treatment of hernia, the pizzle in preparation frequently with natural drying are used as medicine, since pizzle matter is tough and tensile, are not easily broken, it is difficult to it crushes, and And pizzle contain a large amount of fat, save it is improper easily cause to go mouldy, damage by worms, and generate mildew.Therefore frying is commonly used in the market Method covers mildew, and fried concocting method, which results in, holds a greater amount of vegetable oil in pizzle, and the more summer is easy to breathe out and become.

The collagen content of pizzle is up to 98% rich in androgen, protein, fat, can kidney tonifying help sun, cure mainly kidney deficiency The diseases such as impotence, spermatorrhea, soreness and weakness of waist and knees.Modern study proves that animal viscera on biochemical characteristic and constituent structure also there are many with People's similarity, and in terms of have the characteristics that many similar, therefore have to the corresponding organ-tissue of human body Pharmacological action, this is " dirty with dirty benefit " theory.

It is few using pizzle as the product of raw material on the market at present, it is mostly to cook.And directly edible pizzle is substantially not The macromolecular structure of the original protein of pizzle can be changed, such product is difficult to be inhaled by human body as a kind of macromolecular compound It receives and utilizes.

Pizzle is that a kind of nutritive value is higher, a kind of food favorite for people since ancient times.Pizzle is warm-natured, sweet in flavor It is salty, can tonifying kidney and benefiting sperm, cold dispelling establishing-Yang, contained androgen can stimulate the hematopoiesis function of marrow, enhance the disease resistance of human body, due to Its nutritive value is high, referred to as: " public tonic ", amino acid necessary to its protein and human body rich in.But it cuts Only currently, the eating method of people have it is following several: first, being that block after pizzle wash clean, will be cut into and add rock sugar to stew to eat；Its Two, it is that the pizzle after processing steeps use with high spirit；Third, being to be sent out with water or with fry dried food ingredients, be subsequently used for cooking, entertain the guests at a banquet It is used, these methods show that it is all not easy to human consumption and absorbs according to various data.

Freeze-drying is that the processing of nearly all moisture is got rid of from substance from order to save substance.Freeze-drying ( Referred to as it is lyophilized) it is by frozen matter, reduces its temperature and increase heat so that the chilled water in substance is become by distillation It is realized at gas.

In recent years, microwave energy has been proposed for accelerated freezing drying processing.Different from the heat that conduction provides, microwave The outer layer that energy breaks through substance comes so that inside warms and increases rate of sublimation.In such a manner, microwave energy Time and energy needed for freeze-drying potentially being reduced.However, being freeze-dried the use of microwave under required temperature and pressure Propose some challenges, including due to caused by thermal runaway a possibility that damage of product.By using humble wave energy, with more Long drying time is cost, can be minimized these effects.

Microwave drying has the characteristics that liter temperature is fast, rate of drying is fast, free of contamination, preferably kills in addition, microwave also has Worm, fungistatic effect, but microwave is easily assembled at tip, so that material heating is uneven, constrains its answering on medicine is dry With with development.Application No. is 201310568675.1, a kind of entitled Chinese patent application of the concocting method of pizzle is public A kind of method for having opened microwave drying pizzle product, but the method for microwave drying that this application is recorded, drying effect is poor, dry Product moisture content is high, and is not easy in conjunction with other nutrient raw materials.

Summary of the invention

Aiming at the shortcomings in the prior art, the purpose of the present invention is to provide a kind of compound concocting method of pizzle, can have The raising pizzle drying of effect, crushing effect, obtain the pizzle product for being rich in multiple element.

To achieve the goals above, the technical solution adopted by the present invention is that:

A kind of compound concocting method of pizzle, described method includes following steps:

Step 1: pretreatment of raw material；

Step 2: ultrasonic vacuum impregnates；

Step 3: freezing；

Step 4: low-temperature vacuum microwave is dry；

Step 5: crushing；

Step 6: hot wind-it is infrared-microwave drying；

Step 7: packaging.

Wherein, the step 1 includes the following steps:

Step 1) splits pizzle, rejects surrounding fascia and fat, removes impurity removing, is cleaned with clear water；

Pizzle once purged in step 1) is put into container by step 2), is separately added into citric acid 10-15ml/kg, white Wine 15-20ml/kg and ice water 2-3kg/kg impregnates 4-5 hours, and cleaning, draining are spare；

Step 3), the pizzle for obtaining step 2) are put into another container, then are separately added into sodium bicarbonate 1-5g/kg, salt 2~5kg/kg of 1-5g/kg and pure water impregnates 3-4 hours under the conditions of water temperature is 25-27 DEG C, and cleaning, draining are spare；

Step 4), the pizzle for obtaining step 3) carry out 10-30 seconds in far infrared sterilizer, then carry out high temperature again Sterilizing sets sterilising temp range as 120-130 DEG C, is 120-130 DEG C in temperature, and pressure is that 0.2~0.3MPa condition is divided into Surely sterilizing duration range is 30-40 minutes, and the pizzle after sterilizing is quickly cooled down；

Step 5), the pizzle for obtaining step 4), which are placed in water, impregnate 1-24 hours, its water content is made to reach 30- 50%；

Step 6), the pizzle for obtaining step 5) are cut into the disk of 5-7mm thickness.

Wherein, the step 2 includes the following steps:

Step 7), the pizzle slice that step 6) is obtained and dipping slurry, are sliced: dipping slurry=(30- according to pizzle 60): 100 weight ratio is put into closed container；

The vacuum pump that step 8), opening are connect with closed container, extracts the gas in closed container out, in closed container Pizzle slice carries out vacuumizing dipping；Keep container inner pressure constant, 30-60 minutes, meanwhile, in vacuum-pumping container, formed Ultrasonic activation；Ultrasonic power is 500W, ultrasonic time 5min；

Step 9), stopping vacuumize, and restoring the air pressure in closed container is atmospheric pressure, take out and cut by the pizzle of dipping Piece drains, spare.

Wherein, the step 3 includes the following steps:

The pizzle drained slice sealing is placed in constant temperature 1-2h in -15 to -10 DEG C of refrigerator by step 10), is then taken out, It is placed in vacuum freeze drier, is first refrigerated to -40~-50 DEG C with the cooling rate of 5-10 DEG C/min, keep 2-4h, then again It is placed on cryostat 3h in the freezer that library temperature is -32~-36 DEG C.

Wherein, the step 4 includes the following steps:

The pizzle piece that step 10) obtains is placed in vacuum microwave dryer and is dried by step 11), drying temperature 5 DEG C -15 DEG C, drying time 10-20min, for vacuum degree control in 5.0~10kPa, microwave power is 200-400W, obtains drying Pizzle piece.

Wherein, the step 5 includes the following steps:

Pizzle after vacuum drying is crushed to 400 mesh or more in super-micro wall-broken grinder by step 12)；Again to smashed In pizzle powder, the ethyl alcohol of 1.1-1.5 times of pizzle powder weight is added, the concentration of the ethyl alcohol is 40-50%, then by super Sound wave continuous flow cell crusher, supersonic frequency 15-40KHz, power 1000-3000W, flow is 15Kg to suspension per hour, Obtained broken pizzle powder suspension, it is dry, pizzle fine powder is obtained, it is spare.

Wherein, the step 6 includes the following steps:

Step 13), the pizzle fine powder for obtaining step 12), in drying chamber carry out hot wind-it is infrared-microwave drying, hot wind 60~80 DEG C of temperature, 0.10~0.25W/cm of far infrared radiation intensity², microwave heating first stage power is 200~300W, the Two-stage power is 300~400W, and phase III power is 200~300W, conveyor belt speed 1-2m/min, is recycled 5-8 times；It will Pizzle fine powder is dried to moisture content under infrared, microwave environment less than 5%, and pizzle dry powder is obtained.

Wherein, the raw material composition and weight proportion of the dipping slurry are as follows:

5-10 parts of fructus lycii, 5-8 parts of ginseng, 5-7 parts of cordyceps sinensis, 3-6 parts of ganoderma lucidum, 1-2 parts of actinolite, sheep fire leaf 2-3 Part, 1-3 parts of nutmeg, 2-3 parts of Radix Codonopsis, 2-4 parts of the root of Dahurain angelica, 3-4 parts of longan, 4-9 parts of jujube, 10-15 parts of Herba Epimedii, 2-5 parts of Radix Glycyrrhizae, 10-15 parts of Schisandra chinensis, 10-20 parts of rhizoma polygonati, 10-20 parts of deer bone, 1-5 parts of mulberry fruit, 10-15 parts of raspberry, 1-5 parts of cortex cinnamomi, black snake 5-10 parts, 5-10 parts of hippocampus, 1-5 parts of Radix Angelicae Sinensis, 5-15 parts of Chinese yam, 100-200 parts of deionized water；By above-mentioned solid material through powder Broken, grinding crosses 200 meshes, takes minus mesh, be mixed evenly with deionized water, be heated to 40-50 DEG C, constant temperature 30-40min, Then it is down to room temperature, is filtered, taking filtrate is to impregnate slurry.

Wherein, the step 7 packaging specifically:

Pizzle dry powder obtained in step 13) is measured and is packed, carries out pasteurize 10-15 minutes to get finished product.

It is preferred that the raw material composition and weight proportion of the dipping slurry are as follows:

6 parts of fructus lycii, 7 parts of ginseng, 5 parts of cordyceps sinensis, 4 parts of ganoderma lucidum, 1 part of actinolite, 3 parts of sheep fire leaf, 2 parts of nutmeg, party Join 2 parts, 3 parts of the root of Dahurain angelica, 4 parts of longan, 8 parts of jujube, 12 parts of Herba Epimedii, 3 parts of Radix Glycyrrhizae, 11 parts of Schisandra chinensis, 19 parts of rhizoma polygonati, deer bone 16 Part, 3 parts of mulberry fruit, 13 parts of raspberry, 2 parts of cortex cinnamomi, black 7 parts of snake, 8 parts of hippocampus, 4 parts of Radix Angelicae Sinensis, 12 parts of Chinese yam, 150 parts of deionized water.

Pizzle, property is sweet, flat, nontoxic, major function: kidney tonifying, establishing-Yang, strengthening the essence, control strain, waist and knee, kidney deficiency, deafness, ear Ring, impotence, uterus cold infertile control general debility, control married woman's deficiency of blood.

Rhizoma polygonati, nature and flavor, Gan Ping, nontoxic, channel tropism, enter spleen, lung, kidney knot, function cure mainly, tonifying middle-Jiao and Qi, moistening herat and lung, strengthening tendons Bone, governance wasting fever and chills, tuberculosis hemoptysis, after being ill physically weak deficiency of food, muscles and bones is weak, rheumatalgia pain, wind favus disease.

Mulberry fruit, property is sweet, cold, nontoxic, function the major functions: tonifying liver, kidney-nourishing, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow liquid, control the deficiency of liver-yin and kidney-yin, quench one's thirst, constipation, Mesh is dark, deafness, tinnitus, scrofula, articular instability, miscarriage prevention.

Raspberry, nature and flavor, sweet, sour, nontoxic, function controls scrofula carbuncle, purified blood the major functions: enrich blood, is green blood, clearing heat and detoxicating Liquid.

Ginseng, take a tonic or nourishing food to build up one's health the five internal organs, strong spirit, determine soul, stop palpitate with fear, improving eyesight happily, brain healthy, control all chronic diseases marked by deficiency of vital energy of men and women, It reinforces vital energy, promote the production of body fluid to quench thirst.

Cortex cinnamomi, property is pungent, sweet, hot, function the major functions: supplementing Yuanyang, warming spleen and stomach, except stagnant, promoting blood circulation, control the Yang-function insufficiency of kidneyzang, limb cold Weak pulse, yang depletion collapse, abdominal pain diarrhoea, cold hernia renal mass, waist and knee crymodynia, menostasis, negative subcutaneous ulcer, streamer, the floating more, heat in the upper and cold in the lower of empty sun etc..

Fructus lycii, property is sweet, flat, and function controls liver-kidney Yin deficiency, dizziness, dizzy, the more tears of blurred vision, cough the major functions: nourshing kidney, moistening lung, improving eyesight It coughs, quench one's thirst, pass out semen.

Chinese yam, property is sweet, flat, function the major functions: strengthening the spleen and tonifying the lung, reinforce the kidney, control spleen deficiency let out, protracted dysentery, cough due to consumptive disease, quench one's thirst, pass out semen, Leukorrhagia, frequent urination etc..

Black snake: property is sweet, flat, and function controls rheumatoid arthritis stubborn, skin numbness, tuberculous osteoarthropathy, bone the major functions: wind-damp dispelling, degrading the channel The necrosis of stock head, rubeola scabies, leprosy tetanus, infantile paralysis etc..

Beneficial effect

1, it is used in the present invention using plurality of Chinese material as dipping slurry, during processing pizzle, passes through innovation Method, Chinese medicine composition is used in combination with pizzle, the various valuable component contents of the product of acquisition are above existing The pizzle product that method obtains.Wherein, in obtained final pizzle dry powder, deer bone, pizzle etc. are monarch drug in a prescription, tonifying kidney and strengthening yang；With Rhizoma polygonati, mulberry fruit etc. are ministerial drug, tonifying middle-Jiao and Qi, moistening herat and lung, strengthening the bones and muscles；It is adjutant with raspberry, ginseng, cortex cinnamomi etc., assistant pizzle, deer The power of the kidney tonifying of bone；It is to make medicine with black snake, root of Dahurain angelica etc., drug effect is made to go directly each internal organs.

2, the present invention organically combines two technologies of microwave drying and vacuum drying, has given full play to microwave drying and vacuum Dry respective advantage, under vacuum conditions, microwave energy quickly heats from inside to outside, holds that the heat transfer of moisture relatively Easily, therefore drying time greatly shortens, and production efficiency is improved, and energy consumption is substantially reduced, and optimization obtains micro-wave vacuum Optimum process.The effective component that the implementation of the technique can be effectively retained in pizzle reduces the loss of chemical component, when shortening dry Between, production efficiency is improved, and microwave itself can play the role of sterilizing, be conducive to the storage of pizzle.

Detailed description of the invention

Fig. 1 is influence of the different concocting methods to the content of testosterone in pizzle.

Specific embodiment

Embodiment 1

Step 1: pretreatment of raw material；

Step 2: ultrasonic vacuum impregnates；

Step 3: freezing；

Step 4: low-temperature vacuum microwave is dry；

Step 5: crushing；

Step 6: hot wind-it is infrared-microwave drying；

Step 7: packaging.

Wherein, the step 1 includes the following steps:

Pizzle once purged in step 1) is put into container by step 2), is separately added into citric acid 12ml/kg, white wine 17ml/kg and ice water 3kg/kg impregnates 4 hours, and cleaning, draining are spare；

Step 3), the pizzle for obtaining step 2) are put into another container, then are separately added into sodium bicarbonate 4g/kg, salt 3g/ Kg and pure water 3kg/kg impregnates 4 hours under the conditions of water temperature is 26 DEG C, and cleaning, draining are spare；

Step 4), the pizzle for obtaining step 3) carry out 20 seconds in far infrared sterilizer, then carry out high temperature again and go out Bacterium sets sterilising temp range as 120-130 DEG C, when temperature is 120-130 DEG C, and pressure sets sterilizing under the conditions of being 0.3MPa Long range is 30-40 minutes, and the pizzle after sterilizing is quickly cooled down；

Step 5), the pizzle for obtaining step 4), which are placed in water, impregnate 14 hours, its water content is made to reach 35%；

Step 6), the pizzle for obtaining step 5) are cut into the disk of 6mm thickness.

Wherein, the step 2 includes the following steps:

Step 7), the pizzle slice that step 6) is obtained and dipping slurry, are sliced: dipping slurry=50:100 according to pizzle Weight ratio be put into closed container；

The vacuum pump that step 8), opening are connect with closed container, extracts the gas in closed container out, in closed container Pizzle slice carries out vacuumizing dipping；Keep container inner pressure constant, 50 minutes, meanwhile, in vacuum-pumping container, form ultrasound Wave vibration；Ultrasonic power is 500W, ultrasonic time 5min；

Wherein, the step 3 includes the following steps:

The pizzle drained slice sealing is placed in constant temperature 2h in -12 DEG C of refrigerator by step 10), is then taken out, is placed in vacuum In freeze drier, -45 DEG C first are refrigerated to the cooling rate of 6 DEG C/min, keeps 2-4h, being then placed on library temperature again is -33 DEG C freezer in cryostat 3h.

Wherein, the step 4 includes the following steps:

The pizzle piece that step 10) obtains is placed in vacuum microwave dryer and is dried by step 11), drying temperature 8 DEG C, drying time 15min, for vacuum degree control in 7kPa, microwave power is 300W, obtains dried bull penis piece.

Wherein, the step 5 includes the following steps:

Pizzle after vacuum drying is crushed to 400 mesh or more in super-micro wall-broken grinder by step 12)；Again to smashed In pizzle powder, 1.2 times of pizzle powder weight of ethyl alcohol is added, the concentration of the ethyl alcohol is 45%, then connects by ultrasonic wave Afterflow biomixer, supersonic frequency 20KHz, power 2000W, flow is 15Kg to suspension per hour, and what is obtained is broken Pizzle powder suspension, it is dry, pizzle fine powder is obtained, it is spare.

Wherein, the step 6 includes the following steps:

Step 13), the pizzle fine powder for obtaining step 12), in drying chamber carry out hot wind-it is infrared-microwave drying, hot wind Temperature 70 C, far infrared radiation intensity 0.2W/cm², microwave heating first stage power is 250W, and second stage power is 350W, phase III power are 250W, conveyor belt speed 2m/min, are recycled 6 times；By pizzle fine powder under infrared, microwave environment Drying, less than 4%, obtains pizzle dry powder to moisture content.

6 parts of fructus lycii, 7 parts of ginseng, 5 parts of cordyceps sinensis, 4 parts of ganoderma lucidum, 1 part of actinolite, 3 parts of sheep fire leaf, 2 parts of nutmeg, party Join 2 parts, 3 parts of the root of Dahurain angelica, 4 parts of longan, 8 parts of jujube, 12 parts of Herba Epimedii, 3 parts of Radix Glycyrrhizae, 11 parts of Schisandra chinensis, 19 parts of rhizoma polygonati, deer bone 16 Part, 3 parts of mulberry fruit, 13 parts of raspberry, 2 parts of cortex cinnamomi, black 7 parts of snake, 8 parts of hippocampus, 4 parts of Radix Angelicae Sinensis, 12 parts of Chinese yam, 150 parts of deionized water； Above-mentioned solid material is crushed, is ground, 200 meshes is crossed, takes minus mesh, be mixed evenly with deionized water, be heated to 45 DEG C, then constant temperature 35min is down to room temperature, filtering, and taking filtrate is to impregnate slurry.

Wherein, the step 7 packaging specifically:

Pizzle dry powder obtained in step 13) is measured and is packed, carries out pasteurize 12 minutes to get finished product.

Embodiment 2

Step 1: pretreatment of raw material；

Step 2: ultrasonic vacuum impregnates；

Step 3: freezing；

Step 4: low-temperature vacuum microwave is dry；

Step 5: crushing；

Step 6: hot wind-it is infrared-microwave drying；

Step 7: packaging.

Wherein, the step 1 includes the following steps:

Pizzle once purged in step 1) is put into container by step 2), is separately added into citric acid 15ml/kg, white wine 20ml/kg and ice water 3kg/kg impregnates 5 hours, and cleaning, draining are spare；

Step 3), the pizzle for obtaining step 2) are put into another container, then are separately added into sodium bicarbonate 5g/kg, salt 5g/ Kg and pure water 5kg/kg impregnates 4 hours under the conditions of water temperature is 27 DEG C, and cleaning, draining are spare；

Step 4), the pizzle for obtaining step 3) carry out 30 seconds in far infrared sterilizer, then carry out high temperature again and go out Bacterium sets sterilising temp range as 120-130 DEG C, when temperature is 120-130 DEG C, and pressure sets sterilizing under the conditions of being 0.3MPa Long range is 30-40 minutes, and the pizzle after sterilizing is quickly cooled down；

Step 5), the pizzle for obtaining step 4), which are placed in water, impregnate 24 hours, its water content is made to reach 50%；

Step 6), the pizzle for obtaining step 5) are cut into the disk of 7mm thickness.

Wherein, the step 2 includes the following steps:

Step 7), the pizzle slice that step 6) is obtained and dipping slurry, are sliced: dipping slurry=60:100 according to pizzle Weight ratio be put into closed container；

The vacuum pump that step 8), opening are connect with closed container, extracts the gas in closed container out, in closed container Pizzle slice carries out vacuumizing dipping；Keep container inner pressure constant, 60 minutes, meanwhile, in vacuum-pumping container, form ultrasound Wave vibration；Ultrasonic power is 500W, ultrasonic time 5min；

Wherein, the step 3 includes the following steps:

The pizzle drained slice sealing is placed in constant temperature 2h in -10 DEG C of refrigerator by step 10), is then taken out, is placed in vacuum In freeze drier, -50 DEG C first are refrigerated to the cooling rate of 10 DEG C/min, keeps 4h, being then placed on library temperature again is -36 DEG C Freezer in cryostat 3h.

Wherein, the step 4 includes the following steps:

The pizzle piece that step 10) obtains is placed in vacuum microwave dryer and is dried by step 11), drying temperature 15 DEG C, drying time 20min, vacuum degree control 10kPa, microwave power is 400W, obtains dried bull penis piece.

Wherein, the step 5 includes the following steps:

Pizzle after vacuum drying is crushed to 400 mesh or more in super-micro wall-broken grinder by step 12)；Again to smashed In pizzle powder, 1.5 times of pizzle powder weight of ethyl alcohol is added, the concentration of the ethyl alcohol is 50%, then connects by ultrasonic wave Afterflow biomixer, supersonic frequency 40KHz, power 3000W, flow is 15Kg to suspension per hour, and what is obtained is broken Pizzle powder suspension, it is dry, pizzle fine powder is obtained, it is spare.

Wherein, the step 6 includes the following steps:

Step 13), the pizzle fine powder for obtaining step 12), in drying chamber carry out hot wind-it is infrared-microwave drying, hot wind 80 DEG C of temperature, far infrared radiation intensity 0.25W/cm², microwave heating first stage power is 300W, and second stage power is 400W, phase III power are 300W, conveyor belt speed 2m/min, are recycled 8 times；By pizzle fine powder under infrared, microwave environment Drying, less than 5%, obtains pizzle dry powder to moisture content.

10 parts of fructus lycii, 8 parts of ginseng, 7 parts of cordyceps sinensis, 6 parts of ganoderma lucidum, 2 parts of actinolite, 3 parts of sheep fire leaf, 3 parts of nutmeg, party Join 3 parts, 4 parts of the root of Dahurain angelica, 4 parts of longan, 9 parts of jujube, 15 parts of Herba Epimedii, 5 parts of Radix Glycyrrhizae, 15 parts of Schisandra chinensis, 20 parts of rhizoma polygonati, deer bone 20 Part, 5 parts of mulberry fruit, 15 parts of raspberry, 5 parts of cortex cinnamomi, black 10 parts of snake, 10 parts of hippocampus, 5 parts of Radix Angelicae Sinensis, 15 parts of Chinese yam, deionized water 200 Part；Above-mentioned solid material is crushed, is ground, 200 meshes is crossed, takes minus mesh, be mixed evenly with deionized water, is heated to 50 DEG C, then constant temperature 40min is down to room temperature, filtering, and taking filtrate is to impregnate slurry.

Wherein, the step 7 packaging specifically:

Pizzle dry powder obtained in step 13) is measured and is packed, carries out pasteurize 15 minutes to get finished product.

Embodiment 3

Step 1: pretreatment of raw material；

Step 2: ultrasonic vacuum impregnates；

Step 3: freezing；

Step 4: low-temperature vacuum microwave is dry；

Step 5: crushing；

Step 6: hot wind-it is infrared-microwave drying；

Step 7: packaging.

Wherein, the step 1 includes the following steps:

Pizzle once purged in step 1) is put into container by step 2), is separately added into citric acid 10ml/kg, white wine 15ml/kg and ice water 2kg/kg impregnates 4 hours, and cleaning, draining are spare；

Step 3), the pizzle for obtaining step 2) are put into another container, then are separately added into sodium bicarbonate 1g/kg, salt 1g/ Kg and pure water 2kg/kg impregnates 3 hours under the conditions of water temperature is 25 DEG C, and cleaning, draining are spare；

Step 4), the pizzle for obtaining step 3) carry out 10 seconds in far infrared sterilizer, then carry out high temperature again and go out Bacterium sets sterilising temp range as 120-130 DEG C, when temperature is 120-130 DEG C, and pressure sets sterilizing under the conditions of being 0.2MPa Long range is 30-40 minutes, and the pizzle after sterilizing is quickly cooled down；

Step 5), the pizzle for obtaining step 4), which are placed in water, impregnate 1 hour, its water content is made to reach 30%；

Step 6), the pizzle for obtaining step 5) are cut into the disk of 5mm thickness.

Wherein, the step 2 includes the following steps:

Step 7), the pizzle slice that step 6) is obtained and dipping slurry, are sliced: dipping slurry=30:100 according to pizzle Weight ratio be put into closed container；

The vacuum pump that step 8), opening are connect with closed container, extracts the gas in closed container out, in closed container Pizzle slice carries out vacuumizing dipping；Keep container inner pressure constant, 30 minutes, meanwhile, in vacuum-pumping container, form ultrasound Wave vibration；Ultrasonic power is 500W, ultrasonic time 5min；

Wherein, the step 3 includes the following steps:

The pizzle drained slice sealing is placed in constant temperature 1h in -15 DEG C of refrigerator by step 10), is then taken out, is placed in vacuum In freeze drier, -40 DEG C first are refrigerated to the cooling rate of 5 DEG C/min, keeps 2h, being then placed on library temperature again is -32 DEG C Freezer in cryostat 3h.

Wherein, the step 4 includes the following steps:

The pizzle piece that step 10) obtains is placed in vacuum microwave dryer and is dried by step 11), drying temperature 5 DEG C, drying time 10min, for vacuum degree control in 5.0kPa, microwave power is 200W, obtains dried bull penis piece.

Wherein, the step 5 includes the following steps:

Pizzle after vacuum drying is crushed to 400 mesh or more in super-micro wall-broken grinder by step 12)；Again to smashed In pizzle powder, 1.1 times of pizzle powder weight of ethyl alcohol is added, the concentration of the ethyl alcohol is 40%, then connects by ultrasonic wave Afterflow biomixer, supersonic frequency 15KHz, power 1000W, flow is 15Kg to suspension per hour, and what is obtained is broken Pizzle powder suspension, it is dry, pizzle fine powder is obtained, it is spare.

Wherein, the step 6 includes the following steps:

Step 13), the pizzle fine powder for obtaining step 12), in drying chamber carry out hot wind-it is infrared-microwave drying, hot wind Temperature 60 C, far infrared radiation intensity 0.10W/cm², microwave heating first stage power is 200W, and second stage power is 300W, phase III power are 200W, conveyor belt speed 1m/min, are recycled 5 times；By pizzle fine powder under infrared, microwave environment Drying, less than 5%, obtains pizzle dry powder to moisture content.

5 parts of fructus lycii, 5 parts of ginseng, 5 parts of cordyceps sinensis, 3 parts of ganoderma lucidum, 1 part of actinolite, 2 parts of sheep fire leaf, 1 part of nutmeg, party Join 2 parts, 2 parts of the root of Dahurain angelica, 3 parts of longan, 4 parts of jujube, 10 parts of Herba Epimedii, 2 parts of Radix Glycyrrhizae, 10 parts of Schisandra chinensis, 10 parts of rhizoma polygonati, deer bone 10 Part, 1 part of mulberry fruit, 10 parts of raspberry, 1 part of cortex cinnamomi, black 5 parts of snake, 5 parts of hippocampus, 1 part of Radix Angelicae Sinensis, 5 parts of Chinese yam, 100 parts of deionized water； Above-mentioned solid material is crushed, is ground, 200 meshes is crossed, takes minus mesh, be mixed evenly with deionized water, be heated to 40 DEG C, then constant temperature 30min is down to room temperature, filtering, and taking filtrate is to impregnate slurry.

Wherein, the step 7 packaging specifically:

Pizzle dry powder obtained in step 13) is measured and is packed, carries out pasteurize 10 minutes to get finished product.

Product testing:

One, the pizzle powder of distinct methods processing, which increases weight to mouse immune organ, tests

Male juvenile mouse 30 of weight 10-13g are taken, 3 groups, i.e. control group, example 1 group, natural air drying group are randomly divided into, Pizzle dry powder 0.5mL/10g is given in test group stomach-filling, and control group stomach-filling equal amount of distilled water, 1 time a day, successive administration 14 days in last After administration for 24 hours, animal is put to death, is weighed, and dissected and extract thymus gland and spleen respectively, weighed (mg), calculates organ index, internal organs Index (mg/g)=internal organs weight/weight.It the results are shown in Table 1.

The pizzle powder of 1 distinct methods of table processing is to mouse immune organ weight gain experimental result

	Control group	Example 1 group	Natural air drying group
				Thymus index	0.239±0.074	0.385±0.053	0.267±0.085
Index and spleen index	0.421±0.115	0.680±0.083	0.496±0.103

The result shows that the application pizzle powder has the function of significantly enhancing mouse immune organ weight, and effect is good In air-dried pizzle.

Two, the pizzle Yang-strengthening effect of distinct methods processing, is shown in Table 2

The pizzle Yang-strengthening effect of 2 distinct methods of table processing

	It flutters and catches incubation period and (divide)	It flutters and catches number (secondary/30min)
			Control group	15.8±4.2	1.0±1.0
Air-dry group	8.5±5.1	6.2±6.4
			Example 1 group	8.7±4.1	9.8±8.2

The result shows that 1 pizzle yang invigorating functions of embodiment are better than air-dried pizzle.

Finally, it should be noted that obviously, above-described embodiment is only intended to clearly illustrate the application example, and simultaneously The non-restriction to embodiment.For those of ordinary skill in the art, it can also do on the basis of the above description Other various forms of variations or variation out.There is no necessity and possibility to exhaust all the enbodiments.And thus drawn Shen go out obvious changes or variations still in the protection scope of the application type among.

Claims

1. a kind of compound concocting method of pizzle, which is characterized in that described method includes following steps:

Step 1: pretreatment of raw material；

Step 2: ultrasonic vacuum impregnates；

Step 3: freezing；

Step 4: low-temperature vacuum microwave is dry；

Step 5: crushing；

Step 6: hot wind-it is infrared-microwave drying；

Step 7: packaging.

2. compound concocting method according to claim 1, which is characterized in that the step 1 pretreatment of raw material includes as follows Step:

Step 3), the pizzle for obtaining step 2) are put into another container, then are separately added into sodium bicarbonate 1-5g/kg, salt 1-5g/ 2~5kg/kg of kg and pure water impregnates 3-4 hours under the conditions of water temperature is 25-27 DEG C, and cleaning, draining are spare；

Step 4), the pizzle for obtaining step 3) carry out 10-30 seconds in far infrared sterilizer, then carry out high temperature again and go out Bacterium sets sterilising temp range as 120-130 DEG C, and pressure is 0.2~0.3MPa, and sterilizing duration range is 30-40 minutes, sterilizing Pizzle afterwards is cooled down；

Step 5), the pizzle for obtaining step 4), which are placed in water, impregnate 1-24 hours, its water content is made to reach 30-50%；

3. compound concocting method according to claim 1, which is characterized in that the step 3 freezing includes the following steps:

The pizzle drained slice sealing is placed in constant temperature 1-2h in -15 to -10 DEG C of refrigerator by step 10), is then taken out, is placed in In vacuum freeze drier, -40~-50 DEG C first are refrigerated to the cooling rate of 5-10 DEG C/min, 2-4h is kept, then places again The cryostat 3h in the freezer that library temperature is -32~-36 DEG C.

4. compound concocting method according to claim 1, which is characterized in that the dry packet of the step 4 low-temperature vacuum microwave Include following steps:

The pizzle piece that step 10) obtains is placed in vacuum microwave dryer and is dried by step 11), and drying temperature is 5 DEG C -15 DEG C, drying time 10-20min, for vacuum degree control in 5.0~10kPa, microwave power is 200-400W, obtains dried bull penis Piece.

5. compound concocting method according to claim 1, which is characterized in that the step 5 crushing includes the following steps:

Pizzle after vacuum drying is crushed to 400 mesh or more in super-micro wall-broken grinder by step 12)；Again to smashed pizzle In powder, the ethyl alcohol of 1.1-1.5 times of pizzle powder weight is added, the concentration of the ethyl alcohol is 40-50%, then connects by ultrasonic wave Afterflow biomixer, supersonic frequency 15-40KHz, power 1000-3000W, flow is 15Kg to suspension per hour, is obtained Broken pizzle powder suspension, it is dry, pizzle fine powder is obtained, it is spare.

6. compound concocting method according to claim 1, which is characterized in that the step 6 hot wind-is infrared-microwave drying Include the following steps:

Step 13), the pizzle fine powder for obtaining step 12), in drying chamber carry out hot wind-it is infrared-microwave drying, hot blast temperature 60~80 DEG C, 0.10~0.25W/cm of far infrared radiation intensity², microwave heating first stage power is 200~300W, second-order Section power is 300~400W, and phase III power is 200~300W, conveyor belt speed 1-2m/min, is recycled 5-8 times；By pizzle Fine powder is dried to moisture content under infrared, microwave environment less than 5%, and pizzle dry powder is obtained.

7. compound concocting method according to claim 1, which is characterized in that the step 7 packaging specifically: