CN106474348A - 一种治疗风湿筋骨疼痛的中药组合物 - Google Patents

一种治疗风湿筋骨疼痛的中药组合物 Download PDF

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CN106474348A
CN106474348A CN201611138251.1A CN201611138251A CN106474348A CN 106474348 A CN106474348 A CN 106474348A CN 201611138251 A CN201611138251 A CN 201611138251A CN 106474348 A CN106474348 A CN 106474348A
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radix
fructus
rhizoma
cortex
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吕灿利
李岚岚
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Jinxiang County Jin Yi Tang Health Food Co Ltd
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Abstract

本发明涉及一种治疗风湿筋骨疼痛的中药组合物，是由以下原料药制成的：威灵仙、补骨脂、骨碎补、五加皮、黄精、何首乌、熟地黄、鸡血藤、独活、伸筋草、白芍、怀牛膝、木瓜、酒当归、石斛、人参、炒白术、茯苓、山茱萸、肉桂、川芎、菟丝子、枸杞子、杜仲、鹿角胶、龟板胶、炙附片、炙甘草。本发明的制剂在进行内服药物后，其会有先祛风除湿、散寒，再舒筋活络，消炎镇痛的过程，祛风除湿、散寒过程主要是为了排除患者体内湿寒毒造成肢体的变形，再将这些湿寒毒排除体内后，其将会开始舒筋活络，消炎镇痛的功能，进而达到对患者完全治愈。

Description

一种治疗风湿筋骨疼痛的中药组合物
技术领域
本发明涉及中药技术领域，尤其涉及一种治疗风湿筋骨疼痛的中药组合物。
背景技术
风湿、类风湿、关节炎及筋骨疼痛是常见的侵犯关节、骨骼、肌肉、血管及有关软组织或结缔组织为主的疾病，其中多数为自身免疫性疾病。发病多较隐蔽而缓慢，病程较长，且大多具有遗传倾向。患者不仅遭受痛苦，而且还失去了劳动能力，甚至导致生活也不能自理。数千年来我国在治疗风湿、类风湿、关节炎及筋骨疼痛方面，积累了丰富的经验。
但尽管如此，其对各种治疗风湿、类风湿、关节炎及筋骨疼痛的中药成分配比各有不同，并且其所能达到的治疗效果也是不相同的，并且，对于风湿、类风湿、关节炎及筋骨疼痛等疾病的用药量较大，并且中药材原料由于其自身的副作用小、治疗效果较优的特点，使得对中药材原料继续开发应用成为了必然的发展方向。
发明内容
本发明所要解决的技术问题是：为解决上述技术问题，提供了一种用于治疗风湿筋骨疼痛的中药组合物。
一种治疗风湿筋骨疼痛的中药组合物，是由以下原料药制成的：威灵仙15-25、补骨脂10-20、骨碎补10-20、五加皮15-25、黄精12-18、何首乌12-18、熟地黄20-25、鸡血藤10-20、独活8-15、伸筋草18-25、白芍23-30、怀牛膝18-25、木瓜18-25、酒当归18-25、石斛18-25、人参8-15、炒白术12-18、茯苓8-15、山茱萸10-15、肉桂5-8、川芎8-15、菟丝子8-15、枸杞子12-18、杜仲8-15、鹿角胶12-18、龟板胶12-18、炙附片8-15、炙甘草8-15。
优选的，是由以下原料药制成的：威灵仙20、补骨脂15、骨碎补15、五加皮20、黄精15、何首乌15、熟地黄24、鸡血藤15、独活10、伸筋草20、白芍25、怀牛膝20、木瓜20、酒当归20、石斛20、人参10、炒白术15、茯苓10、山茱萸12、肉桂6、川芎10、菟丝子10、枸杞子15、杜仲10、鹿角胶15、龟板胶15、炙附片10、炙甘草10。
可以将上述药物制成药剂学上任何一种剂型如片剂、丸剂、散剂、胶囊，本发明优选的是口服液。
将上述各组份制成本发明所述口服液的具体制备方法是 ：
将上述重量份的药物混合均匀，加水煎煮 2-4 次，每次 0.5-1 小时，合并煎液，过滤，将滤液浓缩成 70℃相对密度 1.15 ～ 1.18 的清膏，冷藏静置，取上清液滤过，滤液中加入常规辅料，混匀，加纯化水至含生药量为 1g/ml，灌封、灭菌制成口服液制剂。
本发明所用中药的药性如下：
威灵仙：【性味】辛、咸，温。【归经】归膀胱经。【功能主治】祛风除湿，通络止痛。用于风湿痹痛，肢体麻木，筋脉拘挛，屈伸不利，骨哽咽喉。
补骨脂：【性味】辛、苦，温。【归经】归肾、脾经。【功能主治】温肾助阳，纳气，止泻。用于阳痿遗精，遗尿尿频，腰膝冷痛，肾虚作喘，五更泄泻；外用治白癜风，斑秃。
骨碎补：【性味】苦，温。【归经】归肾、肝经。【功能主治】补肾强骨，续伤止痛。用于肾虚腰痛，耳鸣耳聋，牙齿松动，跌扑闪挫，筋骨折伤；外治斑秃，白癜风。
五加皮：【性味】辛、苦，温。【归经】归肝、肾经。【功能主治】祛风湿，补肝肾，强筋骨。用于风湿痹痛，筋骨痿软，小儿行迟，体虚乏力，水肿，脚气。
黄精：【性味】甘，平。【归经】归脾、肺、肾经。【功能主治】补气养阴，健脾，润肺，益肾。用于脾胃虚弱，体倦乏力，口干食少，肺虚燥咳，精血不足，内热消渴。
何首乌：【性味】苦、甘、涩，温。【归经】归肝、心、肾经。【功能主治】解毒，消痈，润肠通便。用于瘰疠疮痈，风疹瘙痒，肠燥便秘；高血脂。
熟地黄：【性味】甘，微温。【归经】归肝、肾经。【功能主治】滋阴补血，益精填髓。用于肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴，血虚萎黄，心悸怔忡，月经不调，崩漏下血，眩晕，耳鸣，须发早白。
鸡血藤：【性味】苦、甘，温。【归经】归肝、肾经。【功能主治】补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。
独活：【性味】辛、苦，微温。【归经】归肾、膀胱经。【功能主治】祛风除湿，通痹止痛。用于风寒湿痹，腰膝疼痛，少阴伏风头痛。
伸筋草：【性味】微苦、辛，温。【归经】归肝、脾、肾经。【功能主治】祛风除湿，舒筋活络。用于关节酸痛，屈伸不利。
白芍：【性味】苦、酸，微寒。【归经】归肝、脾经。【功能主治】平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
怀牛膝：【性味】苦、酸，平。【归经】归肝、肾经。【功能主治】补肝肾，强筋骨，逐瘀通经，引血下行。用于腰膝酸痛，筋骨无力，经闭症瘕，肝阳眩晕。
木瓜：【性味】酸，温。【归经】归肝、脾经。【功能主治】平肝舒筋，和胃化湿。用于湿痹拘挛，腰膝关节酸重疼痛，吐泻转筋，脚气水肿。
酒当归：取净当归片，照酒炙法炒干。本品为类圆形或不规则薄片，切面有浅棕色环纹，质柔韧，深黄色，略有焦斑。味甘、微苦，香气浓厚，有酒香气。【性味】甘、辛，温。【归经】归肝、心、脾经。【功能主治】补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。酒当归活血通经。用于经闭痛经，风湿痹痛，跌扑损伤。
石斛：【性能】味甘，性微寒。能养阴清热，益胃生津。
人参：【性味】甘、微苦，平。【归经】归脾、肺、心经。【功能主治】大补元气，复脉固脱，补脾益肺，生津，安神。用于体虚欲脱，肢冷脉微，脾虚食少，肺虚喘咳，津伤口渴，内热消渴，久病虚羸，惊悸失眠，阳痿宫冷；心力衰竭，心原性休克。
炒白术：将蜜炙麸皮撒入热锅内，待冒烟时加入白术片，炒至焦黄色、逸出焦香气，取出，筛去蜜炙麸皮。每 100kg白术片，用蜜炙麸皮10kg。【性味】苦、甘，温。【归经】归脾、胃经。【功能主治】健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。土白术健脾，和胃，安胎。用于脾虚食少，泄泻便溏，胎动不安。
茯苓：【性味】甘、淡，平。【归经】归心、肺、脾、肾经。【功能主治】利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
山茱萸：【性味】酸、涩，微温。【归经】归肝、肾经。【功能主治】补益肝肾，涩精固脱。用于眩晕耳鸣，腰膝酸痛，阳痿遗精，遗尿尿频，崩漏带下，大汗虚脱。内热消渴。
肉桂：【性味】辛、甘，大热。【归经】归肾、脾、心、肝经。【功能主治】补火助阳，引火归源，散寒止痛，活血通经。用于阳痿，宫冷，腰膝冷痛，肾虚作喘，阳虚眩晕，目赤咽痛，心腹冷痛，虚寒吐泻，寒疝，奔豚，经闭，痛经。
川芎：【性味】辛，温。【归经】入肝、胆经。【功能主治】行气开郁，法风燥湿，活血止痛。治风冷头痛旋晕，胁痛腹疼，寒痹筋挛，经闭，难产，产后瘀阻块痛，痈疽疮疡。用于月经不调，经闭痛经，瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛。
菟丝子：【性味】甘，温。【归经】归肝、肾、脾经。【功能主治】滋补肝肾，固精缩尿，安胎，明目，止泻。用于阳痿遗精，尿有余沥，遗尿尿频，腰膝酸软，目昏耳鸣，肾虚胎漏，胎动不安，脾肾虚泻；外治白癜风。
枸杞子：【性味】甘，平。【归经】归肝、肾经。【功能主治】滋补肝肾，益精明目。用于虚劳精亏，腰膝酸痛，眩晕耳鸣，内热消渴，血虚萎黄，目昏不明。
杜仲：【性味】甘，温。【归经】归肝、肾经。【功能主治】补肝肾，强筋骨，安胎。用于肾虚腰痛，筋骨无力，妊娠漏血，胎动不安；高血压。
鹿角胶：【性味】甘、咸，温。【归经】归肾、肝经。【功能主治】温补肝肾，益精养血。用于阳痿滑精，腰膝酸冷，虚劳羸瘦，崩漏下血，便血尿血，阴疽肿痛。
龟板胶：【性味】咸、甘，凉。【归经】归肝、肾、心经。【功能主治】滋阴，养血，止血。用于阴虚潮热，骨蒸盗汗，腰膝酸软，血虚萎黄，崩漏带下。
炙附片：附片，属温里药，性味大辛、大热，有毒。有回阳救逆，温补脾肾，散寒止痛；大辛大热，温阳逐寒之功效。
炙甘草：【性味】甘，平。【归经】归心、肺、脾、胃经 。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
本发明的制剂在进行内服药物后，其会有先祛风除湿、散寒，再舒筋活络，消炎镇痛的过程，祛风除湿、散寒过程主要是为了排除患者体内湿寒毒造成肢体的变形，再将这些湿寒毒排除体内后，其将会开始舒筋活络，消炎镇痛的功能，进而达到对患者完全治愈。
具体实施方式
下面结合实施例对本发明作进一步的说明。
实施例1 制备治疗风湿筋骨疼痛的中药组合物
配方为：威灵仙20、补骨脂15、骨碎补15、五加皮20、黄精15、何首乌15、熟地黄24、鸡血藤15、独活10、伸筋草20、白芍25、怀牛膝20、木瓜20、酒当归20、石斛20、人参10、炒白术15、茯苓10、山茱萸12、肉桂6、川芎10、菟丝子10、枸杞子15、杜仲10、鹿角胶15、龟板胶15、炙附片10、炙甘草10。
制备方法为：将上述重量份的药物混合均匀，加水煎煮 2 ～ 4 次，每次 0.5 ～1 小时，合并煎液，过滤，将滤液浓缩成 70℃相对密度 1.15 ～ 1.18 的清膏，冷藏静置，取上清液滤过，滤液中加入常规辅料，混匀，加纯化水至含生药量为 1g/ml，灌封、灭菌制成口服液制剂。
使用方法 ：口服，每次 1 袋，每袋 500ml，每日三次。
实施例2 制备治疗风湿筋骨疼痛的中药组合物
配方为：威灵仙20.45、补骨脂15.35、骨碎补15.28、五加皮20.66、黄精15.23、何首乌15.51、熟地黄24.98、鸡血藤15.85、独活10.36、伸筋草20.25、白芍25.63、怀牛膝20.05、木瓜20.27、酒当归20.26、石斛20.33、人参10.05、炒白术15.45、茯苓10.23、山茱萸12.55、肉桂6.34、川芎10.94、菟丝子10.36、枸杞子15.48、杜仲10.55、鹿角胶15.05、龟板胶15.07、炙附片10.28、炙甘草10.36。
制备方法同实施例1。
本发明的具体实施例不构成对本发明的限制，凡是采用本发明的相似结构及变化，均在本发明的保护范围内。

Claims (3)

1.一种治疗风湿筋骨疼痛的中药组合物，其特征在于：是由以下原料药制成的：威灵仙15-25、补骨脂10-20、骨碎补10-20、五加皮15-25、黄精12-18、何首乌12-18、熟地黄20-25、鸡血藤10-20、独活8-15、伸筋草18-25、白芍23-30、怀牛膝18-25、木瓜18-25、酒当归18-25、石斛18-25、人参8-15、炒白术12-18、茯苓8-15、山茱萸10-15、肉桂5-8、川芎8-15、菟丝子8-15、枸杞子12-18、杜仲8-15、鹿角胶12-18、龟板胶12-18、炙附片8-15、炙甘草8-15。
2.根据权利要求1所述的一种治疗风湿筋骨疼痛的中药组合物，其特征在于：是由以下原料药制成的：威灵仙20、补骨脂15、骨碎补15、五加皮20、黄精15、何首乌15、熟地黄24、鸡血藤15、独活10、伸筋草20、白芍25、怀牛膝20、木瓜20、酒当归20、石斛20、人参10、炒白术15、茯苓10、山茱萸12、肉桂6、川芎10、菟丝子10、枸杞子15、杜仲10、鹿角胶15、龟板胶15、炙附片10、炙甘草10。
3.根据权利要求1～2中任一项所述的一种治疗风湿筋骨疼痛的中药组合物的制备方法，其特征在于：将上述药物制成药剂学上任何一种剂型如片剂、丸剂、散剂、胶囊。
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Application publication date: 20170308