CN106474262A - A kind of preparation method treating sciatica Chinese medicine composition - Google Patents
A kind of preparation method treating sciatica Chinese medicine composition Download PDFInfo
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- CN106474262A CN106474262A CN201510527096.1A CN201510527096A CN106474262A CN 106474262 A CN106474262 A CN 106474262A CN 201510527096 A CN201510527096 A CN 201510527096A CN 106474262 A CN106474262 A CN 106474262A
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Abstract
The invention provides a kind of preparation method treating sciatica Chinese medicine composition, comprise the following steps：(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis, the 60-80% alcohol reflux of 6-10 times of body of addition 2 times, each 1-3 hour, united extraction liquid in proportion, reclaim ethanol to no alcohol taste, obtain extracting solution A；(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, after the alcohol extraction with step (1) gained, residue merges, the water reflux, extract, of 8-12 times of volume of addition 2 times, each 1-3 hour, united extraction liquid, obtain extracting solution B；(3) merge said extracted liquid A and extracting solution B, 80-90 DEG C of heating 2-4h, be rapidly cooled to 1-5 DEG C, place 48-72h at a temperature of this, obtain aftertreatment fluid；(4) above-mentioned aftertreatment fluid is filtered, be condensed into total extractum that relative density is 1.10-1.16, obtain final product.Preparation method of the present invention, low cost, process is simple, gained Chinese medicine composition being capable of effectively treatment sciatica.
Description
Technical field
The present invention relates to a kind of preparation method treating sciatica Chinese medicine composition, belong to technical field of traditional Chinese medicine preparation.
Background technology
Sciatica is the syndrome based on sciatic nerve pathway and distributed areas pain.Sciatica most absolutely
Number case be secondary to sciatic nerve local and surrounding structure pathological changes to sciatic stimulate compressing with infringement, referred to as continue
Send out sciatica；Minority system constitutional, i.e. sciatic neuritiss.General symptom includes：(1) pain is limited primarily to ischium
Nerve distribution area, outside and foot after back of thighs, shank, the patient of sharp ache can be in distinctive posture；Waist is bent
Bent, go down on one's knees, tiptoe lands.When being located at nerve root as pathological changes, when intraspinal tube pressure increases (coughing, firmly), pain adds
Weight.(2) degree that muscular strength goes down can be widely different because of the degree difference of the cause of disease, diseased region, infringement, can have ischium god
Through domination muscle all or part power weak or paralysis.(3) can be with or without the tenderness of sciatic nerve-trunk at incisura ischiadica.(4)
Sciatic nerve tractive is had to levy, Lasegue levies and its equipotential levies the positive, the presence that this levies is often equal with the order of severity of pain
OK.Local anaesthesia sciatic nerve root or nerve trunk this levy and can disappear.(5) Achilles tendon reflex goes down or disappears, and quadriceps reflex can be because stimulating
And increase.(6) sciatic nerve can be had to arrange going down or disappearing of the various sensations in region, including the pallhypesthesia of external malleolus,
Also can there is extremely light sensory disturbance.
At present, the preparation technology of existing treatment sciatica medicine, its complex process, raw material availability is low, is obtained
Chinese medicine composition effect poor.
Content of the invention
Goal of the invention：In order to overcome the deficiencies in the prior art, the present invention provides one kind to treat sciatica Chinese medicine
The preparation method of compositionss.
Technical scheme：For achieving the above object, the invention provides a kind of preparation treating sciatica Chinese medicine composition
Method, comprises the following steps：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 6-10 times
The 60-80% alcohol reflux of body 2 times, each 1-3 hour, united extraction liquid, reclaims ethanol to no alcohol taste, must carry
Take liquid A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 8-12 times of volume of addition 2 times, each 1-3 hour, and united extraction liquid obtains
Extracting solution B；
(3) merge said extracted liquid A and extracting solution B, 80-90 DEG C of heating 2-4h, be rapidly cooled to 1-5 DEG C, this temperature
Degree is lower to place 48-72h, obtains aftertreatment fluid；
(4) above-mentioned aftertreatment fluid is filtered, be condensed into total extractum that relative density is 1.10-1.16, obtain final product
Preferably, the weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, Squama Maniss 10-30 part, Radix Paeoniae Rubra 15-35 part, Rhizoma Polygoni Cuspidati 15-25 part, Ramulus Cinnamomi 10-20 part,
Radix Rehmanniae Preparata 10-20 part, Cortex Eucommiae 5-25 part, Rhizoma Atractylodis 5-25 part, Semen Persicae 12-24 part, Radix Cyathulae 15-25 part,
Fructus Rubi 10-30 part, Radix Angelicae Pubescentiss 15-35 part, Fructus Lycii 5-15 part.
As another kind preferably, the weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, Squama Maniss 15-25 part, Radix Paeoniae Rubra 20-30 part, Rhizoma Polygoni Cuspidati 18-22 part, Ramulus Cinnamomi 12-18 part,
Radix Rehmanniae Preparata 12-18 part, Cortex Eucommiae 10-20 part, Rhizoma Atractylodis 10-20 part, Semen Persicae 16-20 part, Radix Cyathulae 18-22 part,
Fructus Rubi 15-25 part, Radix Angelicae Pubescentiss 20-30 part, Fructus Lycii 8-12 part.
As another kind preferably, the weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, 20 parts of Squama Maniss, 25 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Polygoni Cuspidati, 15 parts of Ramulus Cinnamomi,
15 parts of Radix Rehmanniae Preparata, 15 parts of the Cortex Eucommiae, 15 parts of Rhizoma Atractylodis, 18 parts of Semen Persicae, 20 parts of Radix Cyathulae,
20 parts of Fructus Rubi, 25 parts of Radix Angelicae Pubescentiss, 10 parts of Fructus Lycii.
As another kind preferably, described total extractum conventionally makes liquid preparation or solid preparation.
As further preferred, described liquid preparation is decoction or oral liquid.
As further preferred, described solid preparation is granule, powder, tablet, pill or capsule.
Beneficial effect：With respect to prior art, preparation method of the present invention, low cost, process is simple, gained Chinese medicine composition
Thing being capable of effectively treatment sciatica.
Specific embodiment
With reference to embodiment, the present invention is further described.
Embodiment 1
Prescription：
10 parts of Scolopendra, 10 parts of Squama Maniss, 15 parts of Radix Paeoniae Rubra, 15 parts of Rhizoma Polygoni Cuspidati, 10 parts of Ramulus Cinnamomi,
10 parts of Radix Rehmanniae Preparata, 5 parts of the Cortex Eucommiae, 5 parts of Rhizoma Atractylodis, 12 parts of Semen Persicae, 15 parts of Radix Cyathulae,
10 parts of Fructus Rubi, 15 parts of Radix Angelicae Pubescentiss, 5 parts of Fructus Lycii.
Preparation technology：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 6 times of bodies
60% long-pending alcohol reflux 1 time, 1 hour every time, united extraction liquid, reclaims ethanol to no alcohol taste, obtains extracting solution
A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 8 times of volumes of addition 1 time, 1 hour every time, and united extraction liquid obtains extraction
Liquid B；
(3) merge said extracted liquid A and extracting solution B, be condensed into total extractum that relative density is 1.10, obtain final product.
According to conventional formulation technique, make tablet.
Embodiment 2
Prescription：
10 parts of Scolopendra, 30 parts of Squama Maniss, 35 parts of Radix Paeoniae Rubra, 25 parts of Rhizoma Polygoni Cuspidati, 20 parts of Ramulus Cinnamomi,
20 parts of Radix Rehmanniae Preparata, 25 parts of the Cortex Eucommiae, 25 parts of Rhizoma Atractylodis, 24 parts of Semen Persicae, 25 parts of Radix Cyathulae,
30 parts of Fructus Rubi, 35 parts of Radix Angelicae Pubescentiss, 15 parts of Fructus Lycii.
Preparation technology：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 10 times of bodies
80% long-pending alcohol reflux 3 times, 3 hours every time, united extraction liquid, reclaims ethanol to no alcohol taste, obtains extracting solution
A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 12 times of volumes of addition 3 times, 3 hours every time, and united extraction liquid must carry
Take liquid B；
(3) merge said extracted liquid A and extracting solution B, be condensed into total extractum that relative density is 1.16, obtain final product.
According to conventional formulation technique, make capsule.
Embodiment 3
Prescription：
10 parts of Scolopendra, 20 parts of Squama Maniss, 25 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Polygoni Cuspidati, 15 parts of Ramulus Cinnamomi,
15 parts of Radix Rehmanniae Preparata, 15 parts of the Cortex Eucommiae, 15 parts of Rhizoma Atractylodis, 18 parts of Semen Persicae, 20 parts of Radix Cyathulae,
20 parts of Fructus Rubi, 25 parts of Radix Angelicae Pubescentiss, 10 parts of Fructus Lycii.
Preparation technology：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 8 times of bodies
70% long-pending alcohol reflux 2 times, 2 hours every time, united extraction liquid, reclaims ethanol to no alcohol taste, obtains extracting solution
A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 10 times of volumes of addition 2 times, 2 hours every time, and united extraction liquid must carry
Take liquid B；
(3) merge said extracted liquid A and extracting solution B, be condensed into total extractum that relative density is 1.13, obtain final product.
According to conventional formulation technique, make pill.
Embodiment 4
Prescription：
10 parts of Scolopendra, 15 parts of Squama Maniss, 20 parts of Radix Paeoniae Rubra, 18 parts of Rhizoma Polygoni Cuspidati, 12 parts of Ramulus Cinnamomi,
12 parts of Radix Rehmanniae Preparata, 10 parts of the Cortex Eucommiae, 10 parts of Rhizoma Atractylodis, 16 parts of Semen Persicae, 18 parts of Radix Cyathulae,
15 parts of Fructus Rubi, 20 parts of Radix Angelicae Pubescentiss, 8 parts of Fructus Lycii.
Preparation technology：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 7 times of bodies
65% long-pending alcohol reflux 2 times, 2 hours every time, united extraction liquid, reclaims ethanol to no alcohol taste, obtains extracting solution
A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 9 times of volumes of addition 2 times, 2 hours every time, and united extraction liquid obtains extraction
Liquid B；
(3) merge said extracted liquid A and extracting solution B, be condensed into total extractum that relative density is 1.12, obtain final product.
According to conventional formulation technique, make granule.
Embodiment 5
Prescription：
10 parts of Scolopendra, 25 parts of Squama Maniss, 30 parts of Radix Paeoniae Rubra, 22 parts of Rhizoma Polygoni Cuspidati, 18 parts of Ramulus Cinnamomi,
18 parts of Radix Rehmanniae Preparata, 20 parts of the Cortex Eucommiae, 20 parts of Rhizoma Atractylodis, 20 parts of Semen Persicae, 22 parts of Radix Cyathulae,
25 parts of Fructus Rubi, 30 parts of Radix Angelicae Pubescentiss, 12 parts of Fructus Lycii.
Preparation technology：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 9 times of bodies
75% long-pending alcohol reflux 1 time, 2 hours every time, united extraction liquid, reclaims ethanol to no alcohol taste, obtains extracting solution
A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 11 times of volumes of addition 2 times, 1 hour every time, and united extraction liquid must carry
Take liquid B；
(3) merge said extracted liquid A and extracting solution B, be condensed into total extractum that relative density is 1.14, obtain final product.
According to conventional formulation technique, make powder.
The test of experimental example preparation method of the present invention gained traditional Chinese medicine composition for treating sciatica
Select 155 sciatica clinical patients, the use of the present invention is embodiment 3,4 and 5 products obtained therefrom, three
After the course for the treatment of, effective percentage up to 95% about, effect is significant.
Claims (7)
1. a kind of preparation method treating sciatica Chinese medicine composition is it is characterised in that comprise the following steps：
(1) weigh Scolopendra, Squama Maniss, Rhizoma Polygoni Cuspidati, Radix Rehmanniae Preparata, the Cortex Eucommiae, Radix Cyathulae and Rhizoma Atractylodis in proportion, add 6-10 times
The 60-80% alcohol reflux of body 2 times, each 1-3 hour, united extraction liquid, reclaims ethanol to no alcohol taste, must carry
Take liquid A；
(2) Radix Paeoniae Rubra, Ramulus Cinnamomi, Semen Persicae, Fructus Rubi, Radix Angelicae Pubescentiss and Fructus Lycii are weighed in proportion, with step (1) gained
After alcohol extraction, residue merges, the water reflux, extract, of 8-12 times of volume of addition 2 times, each 1-3 hour, and united extraction liquid obtains
Extracting solution B；
(3) merge said extracted liquid A and extracting solution B, 80-90 DEG C of heating 2-4h, be rapidly cooled to 1-5 DEG C, this temperature
Degree is lower to place 48-72h, obtains aftertreatment fluid；
(4) above-mentioned aftertreatment fluid is filtered, be condensed into total extractum that relative density is 1.10-1.16, obtain final product.
2. according to claim 1 treatment sciatica Chinese medicine composition preparation method it is characterised in that
The weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, Squama Maniss 10-30 part, Radix Paeoniae Rubra 15-35 part, Rhizoma Polygoni Cuspidati 15-25 part, Ramulus Cinnamomi 10-20 part,
Radix Rehmanniae Preparata 10-20 part, Cortex Eucommiae 5-25 part, Rhizoma Atractylodis 5-25 part, Semen Persicae 12-24 part, Radix Cyathulae 15-25 part,
Fructus Rubi 10-30 part, Radix Angelicae Pubescentiss 15-35 part, Fructus Lycii 5-15 part.
3. according to claim 1 treatment sciatica Chinese medicine composition preparation method it is characterised in that
The weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, Squama Maniss 15-25 part, Radix Paeoniae Rubra 20-30 part, Rhizoma Polygoni Cuspidati 18-22 part, Ramulus Cinnamomi 12-18 part,
Radix Rehmanniae Preparata 12-18 part, Cortex Eucommiae 10-20 part, Rhizoma Atractylodis 10-20 part, Semen Persicae 16-20 part, Radix Cyathulae 18-22 part,
Fructus Rubi 15-25 part, Radix Angelicae Pubescentiss 20-30 part, Fructus Lycii 8-12 part.
4. according to claim 1 treatment sciatica Chinese medicine composition preparation method it is characterised in that
The weight ratio of wherein raw material of Chinese medicine is as follows：
10 parts of Scolopendra, 20 parts of Squama Maniss, 25 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Polygoni Cuspidati, 15 parts of Ramulus Cinnamomi,
15 parts of Radix Rehmanniae Preparata, 15 parts of the Cortex Eucommiae, 15 parts of Rhizoma Atractylodis, 18 parts of Semen Persicae, 20 parts of Radix Cyathulae,
20 parts of Fructus Rubi, 25 parts of Radix Angelicae Pubescentiss, 10 parts of Fructus Lycii.
5. according to claim 1 treatment sciatica Chinese medicine composition preparation method it is characterised in that
Described total extractum conventionally makes liquid preparation or solid preparation.
6. according to claim 5 treatment sciatica Chinese medicine composition preparation method it is characterised in that
Described liquid preparation is decoction or oral liquid.
7. according to claim 5 treatment sciatica Chinese medicine composition preparation method it is characterised in that
Described solid preparation is granule, powder, tablet, pill or capsule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876859A (en) * | 2021-11-16 | 2022-01-04 | 河南省人民医院 | Traditional Chinese medicine composition for treating bone joint movement disorder |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876859A (en) * | 2021-11-16 | 2022-01-04 | 河南省人民医院 | Traditional Chinese medicine composition for treating bone joint movement disorder |
| CN113876859B (en) * | 2021-11-16 | 2023-03-14 | 河南省人民医院 | A topical Chinese medicinal composition for the treatment of bone joint movement disorder |
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Application publication date: 20170308 |