CN106473755A - A kind of optical sound head for blood sugar monitoring - Google Patents
A kind of optical sound head for blood sugar monitoring Download PDFInfo
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- CN106473755A CN106473755A CN201611076201.5A CN201611076201A CN106473755A CN 106473755 A CN106473755 A CN 106473755A CN 201611076201 A CN201611076201 A CN 201611076201A CN 106473755 A CN106473755 A CN 106473755A
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- sound head
- light source
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- 230000003287 optical effect Effects 0.000 title claims abstract description 27
- 239000008280 blood Substances 0.000 title claims abstract description 22
- 210000004369 blood Anatomy 0.000 title claims abstract description 22
- 238000012544 monitoring process Methods 0.000 title claims abstract description 16
- 210000003128 head Anatomy 0.000 claims abstract description 34
- 229910052710 silicon Inorganic materials 0.000 claims abstract description 26
- 239000010703 silicon Substances 0.000 claims abstract description 26
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims abstract description 21
- 241000219739 Lens Species 0.000 claims abstract description 18
- 210000000695 crystalline len Anatomy 0.000 claims abstract description 18
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 6
- 238000002604 ultrasonography Methods 0.000 claims description 5
- 230000005540 biological transmission Effects 0.000 claims description 3
- 230000004446 light reflex Effects 0.000 claims description 3
- 230000002459 sustained effect Effects 0.000 claims description 2
- 230000002463 transducing effect Effects 0.000 claims 2
- 230000003760 hair shine Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000003384 imaging method Methods 0.000 abstract description 3
- 238000005538 encapsulation Methods 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 description 9
- 238000012360 testing method Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000005622 photoelectricity Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 238000010408 sweeping Methods 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0238—Optical sensor arrangements for performing transmission measurements on body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
- A61B8/085—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
Abstract
The present invention discloses a kind of optical sound head for blood sugar monitoring, this detecting head includes LD light source, spectroscope, prism, silicon cell, display lamp, cable, micromachine, arrayed ultrasonic transducer, DOE and convex lenss, can achieve the optoacoustic vascular scan in a panel region.The present invention, using encapsulation integral structure, realizes that excitation apparatus are integrated with scanning means, miniature property and practical, can be widely applied to the fields such as medical science blood vessel imaging, identification, noninvasive dynamics monitoring.
Description
Technical field
The present invention relates to a kind of detection device, more particularly, to a kind of optoacoustic vessel detector, it is suitable for and blood sugar test, doctor
Treat the fields such as imaging, identification detection.
Background technology
Photoacoustic technique be a kind of developed rapidly in recent years, the heart skill based on biological tissue's internal opticses absorption difference
Art, in medical domain, is studied for from the light beam irradiating and detecting body of laser instrument and based on the light of the detection body internal information obtaining
As equipment is always in positive research.Opto-acoustic imaging devices are by bombardment with laser beams to biology.Absorb the biology of laser energy
Tissue occurs volumetric expansion to generate ultrasound wave by the heat that it causes.Ultrasound probe receives the ultrasonic letter of Autonomous test body
Number, rebuild the visualization within biological tissue based on just obtaining photoacoustic signal.
Using the lossless blood sugar detecting method of the ultrasonic non-invasive type as medium, it replaces detection scattering using detection ultrasound wave
Photon, avoids the shortcomings of high optical scattering as methods such as near infrared spectrums, muting sensitivity, low investigation depth from principle,
It is a kind of new blood sugar test technology effectively combining photonic propulsion and ultrasonics.
Content of the invention
It is an object of the invention to for the deficiency making up existing optoacoustic detection technology, there is provided a kind of miniaturization, convenient
Detecting head, by seeming the scanning that device is capable of for a panel region, compared with traditional detection device, do not changing
More beneficial data are obtained in the case of detecting environment.
The technical scheme is that：A kind of optical sound head for blood sugar monitoring, this detecting head includes LD light source, divides
Light microscopic, prism, silicon cell, display lamp, cable, micromachine, miniature array transducer, DOE（Diffraction optical device）
And convex lenss；Detecting head generally cylinder, cylindrical top is embedded with a fixed pan, and LD light source is placed as light source
On fixed pan；Immediately below LD light source, cylinder inwall is provided with annular groove, clamps convex lenss in annular groove；Under convex lenss
Side is prism and micromachine, being interspersed in circular hole by rotary shaft level of prism, and prism another side is external
Micromachine, micromachine is positioned in the inner horizontal direction cylindrical groove of sustained height；In the lower section of prism, cylinder
Inwall is provided with four angle grooves, places tilting spectroscope between four angle grooves, with spectroscope same level in cylinder body
Position is provided with a silicon cell, and four angles of silicon cell embed cylindrical inwall；In spectroscopical position directly below, put
Put a hemispheric diffraction optical device；Miniature array transducer is distributed on cylinder bottom surface；Bottom in total body
Miniature array transducer is embedded in the form of inside groove on face.
The light beam of light source outgoing, through school convex lens collimation, obtains deflecting light, deflect light is irradiated to down after prism
On the spectroscope of side, it is irradiated on DOE through spectroscope in a part of light of spectroscopical effect, another part passes through silicon photoelectricity
Display lamp is accessed in pond, observes light source stability.Deflect light converges through DOE and acts on body surface formation focus point, positioned at spy
The miniature array sensor of gauge head bottom, receives ultrasonic signal；Prism is external to connect micromachine, realizes the micro- of prism
Dynamic, then deflection light can occur micro- change, scan function in feasible region
The emergent light of described LD light source adopts the light beam of near infrared band.
Described convex lenss are used for the emergent light of LD light source is calibrated.
Described prism is connected with micromachine, and minitype motor driving prism rotates, and collimated light irradiation passes through three
There is fine motion after prism, realize the scanning to a zonule.
Described spectroscope adopts semi-transparent semi-reflecting structure, penetrates into following from a deflection light part for prism
On DOE, a part reflexes on the silicon cell facing.
Described silicon cell, positioned at the top of whole optical sound head, receives the light sent out from dichroic mirror, by light
Electric energy can be converted into.Silicon cell and display lamp connect into closed-loop path by transmission cable simultaneously, observe light by display lamp
Source stability.
Described DOE is positioned over the bottom of total using dome-type structure, is derived from spectroscopical light beam for converging.
Described arrayed ultrasonic transducer be located at detecting head bottom surface surrounding, ultrasonic transducer preferably should be less with size
（About 5mm × 5mm）.Ultrasonic the strongest along skin vertical direction energy, the quantity optimizing ultrasonic transducer is carried out with spatial distribution, obtains
Obtain big compared with strong ultrasound intensity and time signal.
The use of this detecting head, comprises the following steps that：The first step：Start micromachine, LD light source sends wave band closely red
The emergent light of wave section；Second step；Because light beam has the angle of divergence, through convex lenss, obtain directional light, directional light is radiated at three
On prism, deflect；Deflection light is radiated on the spectroscope of lower section, and a part of deflect light reflexes to the silicon photoelectricity facing
Chi Shang, a part converges at focus through spectroscope on the DOE of lower section, irradiates and body surface blood vessel；Silicon cell is external
Display lamp, observes stability；On the other hand, motor rotates and drives prism fine motion, realizes the fine motion of light beam, obtains a little section
The purpose of domain scanning；3rd step：Positioned at the miniature transducer of detecting head bottom, receive ultrasonic signal.
It is an advantage of the current invention that：Using miniature entire column type transducer, reduce the volume size of whole device, be easy to
Follow up device realizes integrative packaging effect；This patent adopts micromachine fine motion light path, and simple mechanism achieves a panel region
Surface sweeping, greatly reduce the time of related experiment, the project being conducive to, can be used for later stage blood sugar test and blood vessel positioning, carry
The accuracy of hyperglycemia detection.
Brief description
Fig. 1 is a kind of optical sound head structural representation for blood sugar monitoring of the present invention；
Fig. 2 is a kind of optical sound head side view for blood sugar monitoring of the present invention.
In figure：
1-LD light source, 2- supporting surface, 3- calibration lens, 4- shell, 5- prism, 6- micromachine, 7- spectroscope, 8- silicon photoelectricity
Pond, 9- diffraction optical device, 10- arrayed ultrasonic transducer.
Specific embodiment
It is described further with example below in conjunction with the accompanying drawings.
Fig. 1 is a kind of structure chart of the optical sound head for blood sugar test, and this structure is by LD light source 1, spectroscope 7, folding
Penetrate prism 5, silicon cell 8, display lamp, cable, micromachine 6, miniature array transducer 10, DOE (diffraction optics device
Part) 9 and calibration lens 3 form.LD light source 1 is positioned on embedded supporting surface 2, and convex lenss are fixed by two fixed layer.
The quasi-parallel light of LD light source 1 outgoing, collimates through calibration lens 3, obtains deflecting light, deflection after prism 5
Illumination is mapped on the spectroscope 7 of lower section, is irradiated on DOE 9 through spectroscope 7 in a part of light of effect of spectroscope 7, separately
A part accesses display lamp through silicon cell 8, observes light source stability.Deflect light acts on object through the convergence of DOE 9
Surface forms focus point, positioned at the miniature array sensor 10 of detecting head bottom, receives ultrasonic signal；Prism 5 is followed by micro-
Type motor 6, realizes the rotation of prism 6, then deflection light can change, and realizes scan function；Can get ultrasonic signal.
The emergent light of described LD light source 1 adopts the light beam of wave band near infrared band；
Described convex lenss are used for the emergent light of LD light source is calibrated.
Described prism 5 is connected with micromachine 6, and collimated light irradiation occurs fine motion on prism, realizes to one
The scanning of zonule.
Described spectroscope 7 adopts semi-transparent semi-reflecting structure, penetrates into following from a deflection light part for prism 5
On DOE 9, a part reflexes on the silicon cell 8 facing.
Described silicon cell 8, positioned at the top of whole optical sound head, receives the light from spectroscope 7 reflection, by light
Electric energy can be converted into.Silicon cell and display lamp connect into closed-loop path by transmission cable simultaneously, observe light by display lamp
Source stability.
Described DOE9 is positioned over the bottom of detecting head using dome-type structure, is derived from spectroscopical light beam for converging.
Described arrayed ultrasonic transducer 10 be located at detecting head bottom surface surrounding, ultrasonic transducer preferably should be relatively with size
Little.Ultrasonic the strongest along skin vertical direction energy, the quantity optimizing ultrasonic transducer is carried out with spatial distribution, obtains more ultrasonic
Intensity and time signal.
Using said method, comprise the following steps that：The first step：Start micromachine 6, LD light source 1 sends near infrared band
Quasi-parallel light.Second step；Because light beam has the angle of divergence, through convex lenss 3, obtain directional light, directional light is radiated at Rhizoma Sparganii
On mirror 5, deflect；Deflection light is radiated on the spectroscope 7 of lower section, and a part of deflect light reflexes to the silicon photoelectricity facing
On pond 8, a part converges at focus through spectroscope on the DOE 9 of lower section, irradiates and body surface blood vessel；Silicon cell 8
External display lamp, observes stability；On the other hand, micromachine 6 rotates and drives prism 5 fine motion, realizes the fine motion of light beam, obtains
Purpose to a small region scanning.3rd step：Positioned at the miniature transducer 11 of detecting head bottom, receive ultrasonic signal.
Compared with prior art, using such scheme, benefit of the invention is that：Using miniature entire column type transducer, subtract
The little volume size of whole device, is easy to realize integrative packaging effect with follow up device, can be effectively realized structure
Miniaturization and raising practicality；Feasible region scanning is come using prism.So that light beam is gathered in using DOE subcutaneous, be greatly improved
The launching efficiency of photoacoustic signal；This patent adopts micromachine fine motion light path, and simple mechanism achieves the surface sweeping of a panel region,
Greatly reduce the time of related experiment, the project being conducive to, can be used for the blood vessel positioning of later stage blood sugar test, improve blood glucose
The accuracy of detection.
The present invention is not limited to above-mentioned specific embodiment, those of ordinary skill in the art from above-mentioned design,
Without performing creative labour, a variety of conversion made, it is within the scope of the present invention.
Claims (9)
1. a kind of optical sound head for blood sugar monitoring it is characterised in that：This detecting head includes LD light source（1）, spectroscope
（7）, prism（5）, silicon cell（8）, display lamp, cable, micromachine（6）, miniature array transducer（10）, diffraction light
Learn device（9）And convex lenss（3）；
Detecting head generally cylinder, cylindrical top is embedded with a fixed pan, LD light source（1）It is positioned over solid as light source
Allocate on face；LD light source（1）Underface cylinder inwall is provided with annular groove, clamps convex lenss in annular groove（3）；Convex lenss
Lower section is prism（5）And micromachine（6）, prism（5）While being interspersed in circular hole by rotary shaft level, prism
（5）The external micromachine of another side（6）, micromachine is positioned in the inner horizontal direction cylindrical groove of sustained height；Three
Prism（5）Lower section, cylinder inwall is provided with four angle grooves, places tilting spectroscope between four angle grooves（7）, circle
In cylinder and spectroscope（7）Same level position is provided with a silicon cell（8）, silicon cell（8）Four angles embed cylinder
The inwall of body；In spectroscopical position directly below, place a hemispheric diffraction optical device（9）；Miniature array transducer
（10）It is distributed on cylinder bottom surface；Miniature array transducing is embedded in the form of inside groove on the bottom surface of total body
Device（10）.
2. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：The emergent light of described LD light source
Light beam using near infrared band.
3. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：Described convex lenss are used for LD
The emergent light of light source is calibrated.
4. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：Described prism and micro electric
Machine is connected, and minitype motor driving prism rotates.
5. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：Described spectroscope adopts semi-transparent
Half anti-structure, the deflection light part from prism penetrates into following diffraction optical device（9）On, part reflection
To on the silicon cell facing.
6. it is used for the optical sound head of blood sugar monitoring according to claim 1 it is characterised in that described silicon cell, positioned at whole
The top of individual optical sound head, receives the light sent out from dichroic mirror, converts light energy into electric energy；Simultaneously silicon cell and
Display lamp connects into closed-loop path by transmission cable, observes light source stability by display lamp.
7. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：Described diffraction optical device
（9）It is positioned over the bottom of total using dome-type structure, be derived from spectroscopical light beam for converging.
8. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：Described arrayed ultrasonic transducing
Device is located at the surrounding of detecting head bottom surface, the size 5mm × 5mm of ultrasonic transducer；Ultrasonic the strongest along skin vertical direction energy, excellent
The quantity changing ultrasonic transducer is carried out with spatial distribution, obtains big compared with strong ultrasound intensity and time signal.
9. according to claim 1 be used for blood sugar monitoring optical sound head it is characterised in that：The use of this detecting head, tool
Body step is as follows：The first step：Start micromachine, LD light source sends the emergent light near infrared band for the wave band；Second step；Due to
There is the angle of divergence in light beam, through convex lenss, obtain directional light, directional light is radiated on prism, deflects；Deflection light shines
Penetrate on the spectroscope of lower section, a part of deflect light reflexes on the silicon cell facing, a part arrives down through spectroscope
Focus is converged on the diffraction optical device 9 of side, irradiates and body surface blood vessel；The external display lamp of silicon cell, observes stable
Property；On the other hand, motor rotates and drives prism fine motion, realizes the fine motion of light beam, obtains the purpose of a small region scanning；The
Three steps：Positioned at the miniature transducer of detecting head bottom, receive ultrasonic signal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611076201.5A CN106473755A (en) | 2016-11-30 | 2016-11-30 | A kind of optical sound head for blood sugar monitoring |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611076201.5A CN106473755A (en) | 2016-11-30 | 2016-11-30 | A kind of optical sound head for blood sugar monitoring |
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| Publication Number | Publication Date |
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| CN106473755A true CN106473755A (en) | 2017-03-08 |
Family
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| CN201611076201.5A Pending CN106473755A (en) | 2016-11-30 | 2016-11-30 | A kind of optical sound head for blood sugar monitoring |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107157491A (en) * | 2017-07-21 | 2017-09-15 | 江西科技师范大学 | Light sound blood sugar detection means and method that a kind of blood vessel is automatically positioned |
| CN107228904A (en) * | 2017-07-21 | 2017-10-03 | 江西科技师范大学 | A kind of photic ultrasonic non-invasive glucose monitoring device and method |
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| CN107228904A (en) * | 2017-07-21 | 2017-10-03 | 江西科技师范大学 | A kind of photic ultrasonic non-invasive glucose monitoring device and method |
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