CN106470724A - 鼻腔给药 - Google Patents

鼻腔给药 Download PDF

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Publication number
CN106470724A
CN106470724A CN201580034749.0A CN201580034749A CN106470724A CN 106470724 A CN106470724 A CN 106470724A CN 201580034749 A CN201580034749 A CN 201580034749A CN 106470724 A CN106470724 A CN 106470724A
Authority
CN
China
Prior art keywords
devices
alternatively
nasal
delivery
sumatriptan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580034749.0A
Other languages
English (en)
Chinese (zh)
Inventor
佩尔·吉泽尔·尤佩斯兰
拉米·A·穆罕默德
约翰·穆西纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptinos Co ltd
Original Assignee
Optinose AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/315,132 external-priority patent/US11554229B2/en
Application filed by Optinose AS filed Critical Optinose AS
Publication of CN106470724A publication Critical patent/CN106470724A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0098—Activated by exhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580034749.0A 2014-06-25 2015-06-25 鼻腔给药 Pending CN106470724A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/315,132 2014-06-25
US14/315,132 US11554229B2 (en) 2013-03-26 2014-06-25 Nasal administration
PCT/EP2015/064463 WO2015197798A1 (en) 2014-06-25 2015-06-25 Nasal administration

Publications (1)

Publication Number Publication Date
CN106470724A true CN106470724A (zh) 2017-03-01

Family

ID=53489954

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580034749.0A Pending CN106470724A (zh) 2014-06-25 2015-06-25 鼻腔给药

Country Status (14)

Country Link
EP (2) EP3160556A1 (enExample)
JP (2) JP6785227B2 (enExample)
KR (1) KR102458964B1 (enExample)
CN (1) CN106470724A (enExample)
AU (3) AU2015279154A1 (enExample)
BR (1) BR112016029926A2 (enExample)
CA (1) CA2953207A1 (enExample)
ES (1) ES3034743T3 (enExample)
IL (1) IL249585B (enExample)
MX (1) MX390453B (enExample)
RU (1) RU2016152090A (enExample)
SG (1) SG11201610685XA (enExample)
WO (1) WO2015197798A1 (enExample)
ZA (1) ZA201608785B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108421138A (zh) * 2017-12-25 2018-08-21 宫本海 一种鼻腔雾化吸药器
CN111182934A (zh) * 2017-08-30 2020-05-19 因多西斯有限公司 多剂量药物输送装置
CN111386137A (zh) * 2017-09-26 2020-07-07 株式会社新日本科学 鼻内递送装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11259717B2 (en) * 2018-05-16 2022-03-01 Massachusetts Institute Of Technology Methods and apparatus for passive, proportional, valveless gas sampling and delivery
US12478292B2 (en) 2019-10-28 2025-11-25 The Research Foundation For The State University Of New York Devices, systems, and methods of monitoring arterial carbon dioxide

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1805730A (zh) * 2003-04-16 2006-07-19 默克专利股份有限公司 鼻用药物制剂和使用方法
US20070125371A1 (en) * 2003-08-28 2007-06-07 Optinose As Delivery devices
US20090304802A1 (en) * 2006-03-03 2009-12-10 Optinose As Nasal delivery
US20100242959A1 (en) * 2006-07-25 2010-09-30 Per Gisle Djupesland Delivery of gases to the nasal airway
CN101918061A (zh) * 2007-10-03 2010-12-15 奥普蒂诺斯公司 鼻腔递送装置
US20120073571A1 (en) * 1999-03-03 2012-03-29 Optinose As Nasal delivery device
WO2012163501A1 (de) * 2011-05-27 2012-12-06 Meda Pharma Gmbh & Co. Kg Nasale pharmazeutische formulierung enthaltend fluticason
US8398580B2 (en) * 1999-11-08 2013-03-19 Capnia, Inc. Methods and apparatus for treating rhinitis
CN103463716A (zh) * 2005-02-23 2013-12-25 奥普蒂诺斯公司 粉末传送装置
WO2014155192A2 (en) * 2013-03-26 2014-10-02 Optinose As Nasal administration

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416884D0 (en) * 1994-08-20 1994-10-12 Danbiosyst Uk Drug delivery compositions
KR100692422B1 (ko) 1999-03-03 2007-03-09 옵티노즈 에이에스 코 내부로 물질을 전달하는 장치
CA2375679C (en) 1999-07-12 2008-09-23 Capnia, Incorporated Methods and apparatus for relieving headaches, rhinitis and other common ailments
AU2206801A (en) * 1999-12-24 2001-07-09 Alan Leslie Cripps Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
EP1259282A4 (en) 2000-02-28 2007-05-23 Capnia Inc METHOD AND DEVICE FOR THE TRANSCUTANEOUS INFUSION OF CARBON DIOXIDE FOR LOCAL PAIN TREATMENT AND THE TREATMENT OF OTHERS
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
GB2403154B (en) * 2002-04-04 2007-01-24 Optinose As Nasal devices
MXPA06002075A (es) * 2003-08-29 2006-05-19 Glaxo Group Ltd Inhalador de dosis farmaceutica medida y metodos relacionados.
CA2575932A1 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
GB0602980D0 (en) * 2006-02-14 2006-03-29 Optinose As Delivery device and method
US8337817B2 (en) 2006-12-26 2012-12-25 Shin Nippon Biomedical Laboratories, Ltd. Preparation for transnasal application
GB2448193A (en) * 2007-04-05 2008-10-08 Optinose As Nasal delivery device
WO2009095684A1 (en) 2008-02-01 2009-08-06 Vectura Limited Pulmonary formulations of triptans
US20100196483A1 (en) * 2009-02-04 2010-08-05 Activaero Gmbh Research & Development Method for treatmentof severe and uncontrollable asthma
MX2014009898A (es) 2012-02-16 2015-07-06 Capnia Inc Dispensador de gas con boquilla de difusion.

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120073571A1 (en) * 1999-03-03 2012-03-29 Optinose As Nasal delivery device
US8398580B2 (en) * 1999-11-08 2013-03-19 Capnia, Inc. Methods and apparatus for treating rhinitis
CN1805730A (zh) * 2003-04-16 2006-07-19 默克专利股份有限公司 鼻用药物制剂和使用方法
US20070125371A1 (en) * 2003-08-28 2007-06-07 Optinose As Delivery devices
CN103463716A (zh) * 2005-02-23 2013-12-25 奥普蒂诺斯公司 粉末传送装置
US20090304802A1 (en) * 2006-03-03 2009-12-10 Optinose As Nasal delivery
US20100242959A1 (en) * 2006-07-25 2010-09-30 Per Gisle Djupesland Delivery of gases to the nasal airway
CN101918061A (zh) * 2007-10-03 2010-12-15 奥普蒂诺斯公司 鼻腔递送装置
WO2012163501A1 (de) * 2011-05-27 2012-12-06 Meda Pharma Gmbh & Co. Kg Nasale pharmazeutische formulierung enthaltend fluticason
WO2014155192A2 (en) * 2013-03-26 2014-10-02 Optinose As Nasal administration

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111182934A (zh) * 2017-08-30 2020-05-19 因多西斯有限公司 多剂量药物输送装置
CN111386137A (zh) * 2017-09-26 2020-07-07 株式会社新日本科学 鼻内递送装置
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US12102754B2 (en) 2017-09-26 2024-10-01 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN108421138A (zh) * 2017-12-25 2018-08-21 宫本海 一种鼻腔雾化吸药器

Also Published As

Publication number Publication date
CA2953207A1 (en) 2015-12-30
JP6785227B2 (ja) 2020-11-18
MX2016017038A (es) 2017-05-01
AU2020202029A1 (en) 2020-04-09
SG11201610685XA (en) 2017-01-27
WO2015197798A1 (en) 2015-12-30
ES3034743T3 (en) 2025-08-22
JP2020179191A (ja) 2020-11-05
JP7090124B2 (ja) 2022-06-23
AU2015279154A1 (en) 2017-01-12
RU2016152090A (ru) 2018-07-27
EP4233950A1 (en) 2023-08-30
JP2017520364A (ja) 2017-07-27
AU2021215246A1 (en) 2021-09-09
ZA201608785B (en) 2019-10-30
IL249585A0 (en) 2017-02-28
KR102458964B1 (ko) 2022-10-25
MX390453B (es) 2025-03-19
RU2016152090A3 (enExample) 2019-02-15
EP4233950B1 (en) 2025-06-25
IL249585B (en) 2021-04-29
EP3160556A1 (en) 2017-05-03
BR112016029926A2 (pt) 2017-08-22
KR20170035919A (ko) 2017-03-31
EP4233950C0 (en) 2025-06-25

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Legal Events

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PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20221107

Address after: Pennsylvania, America

Applicant after: Aptinos Co.,Ltd.

Address before: Oslo, Norway

Applicant before: OptiNose A/S