CN106421102A - 一种土元补肾除湿酒及其制备方法 - Google Patents
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Abstract
本发明涉及一种土元补肾除湿酒及其制备方法。该补肾除湿酒是由以下中药材泡酒后制备而成：土元、独活、上山虎、龙眼树寄生、太子参、鸡血藤、刺五加、熟地。具有补肾除湿除湿，活血通络止痛的功效。
Description
技术领域
本发明涉及饮料酒领域，具体涉及一种土元补肾除湿酒及其制备方法。
背景技术
土元，又叫地鳖虫、土鳖虫等，是传统的名贵中药，已有两千多年历史，是理血伤科中药。药用价值高，应用广泛，常用于跌打损伤，消肿止痛，通络理伤，接筋续骨有明显疗效。目前市场上的跌打丸、治伤散、消肿膏、云香精、黑鬼油等百余种中成药，其中土元是不可缺少的组成部分。近年来，许多高级宾馆、饭店还常用土元做高级菜肴，接待贵宾，食之可口，营养价值更是身价百倍，其用量逐年增长，供不应求。
地鳖虫类中药使用历史悠久，几乎所有著名药典对其都有明确的记载，如汉代的我国第一部药物著作《神农本草经》、东汉著名医学家张仲景的《金匮要略》以及明代李时珍的《本草纲目》等。其功能主治也得到了研究应用及发展，具有逐瘀、破积、通络、理伤等功能，主治瘕即包块、肿块、肿瘤之意]积聚、经闭，产后瘀血腹痛，跌打损伤等。
其主要成分为谷氨酸等17种氨基酸和砷等28种多种微量元素以及甾醇和直链脂肪族化合物。有抗血栓形成和溶解血栓的作用；提取物可抑制血小板聚集和粘附率，减少聚集数；总生物碱可提高心肌和脑对缺血的耐受力，并降低心、脑组织的耗氧量；水煎液具有调脂作用，能延缓动脉粥样硬化的形成；提取物可抑制D-半乳糖所致的肝损害而有保肝作用。临床研究表明，可治疗高血压，冠心病、骨折、急性腰扭伤、坐骨神经痛、劳伤性胸痛以及晚期肿瘤等。
酒性温而味辛，温者能祛寒，辛者能发散，所以酒能疏通经脉、行气和血、蠲痹散结、温阳祛寒，能疏肝解郁、宣情畅意。又因为酒为谷物酿造之精华，故还能补益肠胃。《博物志》载：王肃、张衡、马均三人冒雾晨行。一人饮酒，一人饮食，一人空腹。空腹者死，饱食者病，饮酒者健。这表明“酒势辟恶，胜于作食之效也。”酒与药物的结合是饮酒养生的一大进步。中国的历代医药著作中几乎无一例外地有药酒治疾健身的记载。人类最初的饮酒行为虽然还不能称之为饮酒养生，但却与补肾除湿养生有着密切的联系。最初的酒是人类采集的野生水果在剩余的时候得到适宜条件自然发酵而成的，由于许多野生水果本身就具有药用价值，所以最初的酒可以称得上是天然的“补肾除湿酒”，它对人体健康有一定的保护和促进作用。今天随着科学技术的进步，从中药浸酒的传统工艺的基础上已发展到利用萃取、浸提和生物工程等现代化手段，提取中药中的有效成份制成高含量的功能药酒。
发明内容
本发明的目的是提供一种土元补肾除湿酒；
本发明的另一目的是提供一种土元补肾除湿酒的制备方法。
本发明的目的是通过下列的技术方案实现的：
本发明所述的土元补肾除湿酒，是由包括以下重量份的原料制备而成：
土元3-10份、独活10-30份、上山虎1-3份、龙眼树寄生10-30份、太子参10-30份、鸡血藤10-30份、刺五加10-30份、熟地10-30份。
优选地，是由以下重量份的原料制备而成：
土元5份、独活20份、上山虎1份、龙眼树寄生20份、太子参20份、鸡血藤20份、刺五加20份、熟地20份。
以下是本发明土元补肾除湿酒的药材来源：
土元（ground beetle )别名： 可泡虫、地鳖虫、土鳖、过街、地乌龟、节节虫、臭虫母、地鳖。属于昆虫，身体扁，棕黑色，雄的有翅膀，雌的无翅。咸，寒。活血散瘀，通经止痛。主治：跌打损伤，淤血肿痛，闭经，产后瘀血腹痛。
本发明的另一方面是提供了本发明土元补肾除湿酒的制备方法：
（1）取全部8味药材，净选、灭菌、干燥、切碎；
（2）切碎后的药材加冰糖和酒基浸泡30-40天；
（3）将浸泡所得药酒液过滤，得滤液；
（4）滤液加水和米酒调配成800-1500份，酒度为25-45%；
（5）调配好的药酒液自然澄清后过滤；
（6）过滤后的酒液储存7天，即得所述补肾除湿酒。
本发明土元补肾除湿酒的制备方法优选如下：
（1）取全部8味药材，净选、灭菌、干燥、切碎；
（2）切碎后的药材加入冰糖和酒基浸泡35天；
（3）将浸泡所得药酒液过滤，得滤液；
（4）滤液加水和米酒调配成1000份，酒度为32%；
（5）调配好的药酒液自然澄清后过滤；
（6）过滤后的酒液储存7天，即得所述补肾除湿酒。
本发明采用多种补肾除湿除湿、活血通络的中药进行合理配制，治疗各种痛风顽痹、风湿痹痛，肢体麻痹，腰膝冷痛。方中土元活血散瘀，通经止痛；独活补肾除湿活血，解毒止痛；上山虎祛湿止痛；龙眼树寄生活络活血；太子参补肝肾，强筋骨；鸡血藤活血通络；刺五加补肾安神；熟地滋阴补肾除湿，并“以酒为使”，引导诸药迅速奏效。具有补肾除湿除湿，活血通络止痛的功效。
本发明提供的一种土元补肾除湿酒具有以下优点：
1、本发明提供的土元补肾除湿酒具有补肾除湿除湿，活血通络止痛的功效。
2、临床观察表明，本发明土元补肾除湿酒对痹症的常见症状关节及肌肉疼痛、麻木，晨僵，关节肿胀，屈伸不利，血沉等均有较好的改善作用，改善情况优于对照组；总有效率为96.2%，疗效显著高于对照组。
3、本发明风味独特、口感佳，改变了土元食用方法单一的现状，增加了土元的产品附加值。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。
实施例1
土元5kg、独活20kg、上山虎1kg、龙眼树寄生20kg、太子参20kg、鸡血藤20kg、刺五加20kg、熟地20kg、冰糖40kg。取全部8味药材，净选、灭菌、干燥、切碎，用酒精度为60%酒基400kg浸泡30天，浸泡所得药酒液过滤，取滤液加水和米酒调配成800kg，调酒度为25%，调配好的药酒液打入半成品缸，自然澄清后过滤，过滤后的酒液储存5天，即得所述补肾除湿酒，检验后灌装。
实施例2
土元3kg、独活10kg、上山虎1kg、龙眼树寄生10kg、太子参10kg、鸡血藤10kg、刺五加10kg、熟地10kg。取全部8味药材，净选、灭菌、干燥、切碎，加入冰糖40kg，用酒精度为70%酒基500kg浸泡35天，浸泡所得药酒液过滤，取滤液加水和米酒调配成1000kg，调酒度为32%，调配好的药酒液打入半成品缸，自然澄清后过滤，过滤后的酒液储存7天，即得所述补肾除湿酒，检验后灌装。
实施例3
土元10kg、独活30kg、上山虎3kg、龙眼树寄生30kg、太子参30kg、鸡血藤30kg、刺五加30kg、熟地30kg。取全部8味药材，精选、清洗、灭菌、干燥、切碎，用酒精度为80%酒基600kg浸泡40天，浸泡所得药酒液过滤，取滤液加水和米酒调配成1500kg，调酒度为45%，调配好的药酒液打入半成品缸，自然澄清后过滤，过滤后的酒液储存10天，即得所述补肾除湿酒，检验后进行灌装。
实施例4
土元8kg、独活15kg、上山虎2kg、龙眼树寄生25kg、太子参15kg、鸡血藤3kg、刺五加25kg、熟地15kg。取全部8味药材，精选、清洗、灭菌、干燥、切碎，加入冰糖60kg，用酒精度为80%酒基450kg浸泡32天，浸泡所得药酒液过滤，取滤液加水和米酒调配成900kg，调酒度为28%，调配好的药酒液打入半成品缸，自然澄清后过滤，过滤后的酒液储存8天，即得所述补肾除湿酒，检验后灌装。
实施例5
土元5kg、独活20kg、上山虎2kg、龙眼树寄生15kg、太子参30kg、鸡血藤25kg、刺五加10kg、熟地25kg。取全部8味药材，精选、清洗、灭菌、干燥、切碎，加入冰糖50kg，用酒精度为65%酒基550kg浸泡37天，浸泡所得药酒液过滤，取滤液加水和米酒调配成900kg，调酒度为40%，调配好的药酒液打入半成品缸，自然澄清后过滤，过滤后的酒液储存6天，即得所述补肾除湿酒，检验后灌装。
临床试验
1 基本资料
本组案例共120例，其中男性36人, 女性84人, 平均年龄48岁(30岁～63岁)。随机分成实验组78人及对照组42人。全部病例按中医诊断标准和西医诊断标准确诊。
2 方法
实验组:服用本发明实施例1制得的补肾除湿酒, 每次15ml～25ml, 每日1～ 2次,15d为一疗程, 共治疗2～3疗程；
对照组:服用非甾体类药物消炎痛或氨糖类辛片, 25mg至50mg/次, 每日1～ 2次, 饭后温开关送服, 疗程仍以15d为一疗程, 治疗2～3疗程。
3 疗效判断标准
完全缓解:症状全部缓解,功能活动恢复正常，主要医学理化检查指标正常；
显效:全部症状消除或主要症状消除,关节功能基本恢复,能参加正常工作或劳动，理化指标基本正常；
有效:主要症状基本消除,主要关节功能基本恢复或有明显进步, 生活不能自理转为能够自理, 或者失去工作和劳动能力转为能力有所恢复，主要理化指标有所改善；
无效:和治疗前相比较各方面均无进步。
4结果
4.1 临床症状改善比较，见表1。
表1 临床症状改善比较
4.2 疗效比较，见表2.
注：*表示与对照组相比，P＜0.5。
临床结果显示：本发明土元补肾除湿酒对痹症的常见症状关节及肌肉疼痛、麻木，晨僵，关节肿胀，屈伸不利，血沉等均有较好的改善作用，改善情况优于对照组；总有效率为96.2%，疗效显著高于对照组。
虽然，上文中已经用一般性说明、具体实施方式及试验，对本发明作了详尽的描述，但在本发明基础上，可以对之作一些修改或改进，这对本领域技术人员而言是显而易见的。因此，在不偏离本发明精神的基础上所做的这些修改或改进，均属于本发明要求保护的范围。
Claims (4)
1.一种土元补肾除湿酒及其制备方法，其特征在于是由以下重量份的原料制备而成：土元3-10份、独活10-30份、上山虎1-3份、龙眼树寄生10-30份、太子参10-30份、鸡血藤10-30份、刺五加10-30份、熟地10-30份。
2.如权利要求1所述的土元补肾除湿酒，其特征在于是由以下重量份的原料制备而成：土元5份、独活20份、上山虎1份、龙眼树寄生20份、太子参20份、鸡血藤20份、刺五加20份、熟地20份。
3.如权利要求1或2所述的土元补肾除湿酒，其特征在于，它是通过以下方法制备而成的：
取全部8味药材，净选、灭菌、干燥、切碎；
切碎后的药材加冰糖和酒基浸泡30-40天；
将浸泡所得药酒液过滤，得滤液；
滤液加水和米酒调配成800-1500份，酒度为25-45%；
调配好的药酒液自然澄清后过滤；
过滤后的酒液储存5-10天，即得所述补肾除湿酒。
4.如权利要求1或2所述的土元补肾除湿酒，其特征在于，它是通过以下方法制备而成的：
取全部10味药材，净选、灭菌、干燥、切碎；
切碎后的药材加入冰糖和酒基浸泡35天；
将浸泡所得药酒液过滤，得滤液；
滤液加水和米酒调配成1000份，酒度为32%；
调配好的药酒液自然澄清后过滤；
过滤后的酒液储存7天，即得所述补肾除湿酒。
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