CN106420930A - Traditional Chinese medicine unguent for treating psoriasis and preparing method thereof - Google Patents

Traditional Chinese medicine unguent for treating psoriasis and preparing method thereof Download PDF

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CN106420930A
CN106420930A CN201611008917.1A CN201611008917A CN106420930A CN 106420930 A CN106420930 A CN 106420930A CN 201611008917 A CN201611008917 A CN 201611008917A CN 106420930 A CN106420930 A CN 106420930A
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chinese medicine
semen sojae
sojae atricolor
fructus kochiae
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赵群鑫
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses traditional Chinese medicine unguent for treating psoriasis. The unguent comprises 10-14 parts of paper mulberry sap, 10-15 parts of pine tar, 10-15 parts of fructus Kochiae Scopariae, 15-20 parts of lithospermum erthrorhizon, 10-15 parts of indigo pulverata levis, 5-8 parts of black soybean extracts and 3-8 parts of borneol. The invention has the advantages that the traditional Chinese medicine materials are adopted as the materials for treating the psoriasis; meanwhile, starting with the quick effects of supporting the healthy energy and consolidating the body, clearing away heat and toxic materials, clearing heat and drying dampness, dispelling wind and reliving internal heat or fever, dispelling wind and arresting itching, the medicine conducts treatment according to comprehensive diagnosis of the patients, so that factors causing the psoriasis can be eliminated, and area parts of the psoriasis can be comprehensively adjusted. The medicine has no hormone, no toxic and side effects, thus guaranteeing that the patient can feel relived and safe during using process.

Description

One kind treats psoriasic Chinese medicine ointment and preparation method thereof
Technical field
The present invention relates to externally applied agent for treating psoriasis cream treatment field, more particularly to one kind treat psoriasic in Medicine ointment and preparation method thereof.
Background technology
It is commonly called as psoriasiss, be a kind of common chronic inflammatory dermatoses being easy to recur with characteristic skin lesion.Just Rising is inflammatory red papules, and about to Semen phaseoli radiati size, gradually expanding later or merging becomes brownish red speckle to foxtail millet grain, clear border, Surrounding has inflammatory blush, and substantially, surface covers canescence or the silvery white squama that multilamellar is dried for substrate infiltration.Gently scraper surface Squama, gradually exposes one layer of shinny semitransparent thin film of pale red, claims film phenomenon.Strike off thin film again, then little petechia occur, Claim petechial hemorrhage phenomenon.White squama, shinny thin film and petechial hemorrhage are to diagnose psoriatic key character, and referred to as three levy. Psoriasis vulgaris are broadly divided into three periods from generation to finally disappearing：Enter the departure date, resting stage, catagen.
Antipsoriatics product curative effect is not up to expectations on the market at present, and has many side effect and untoward reaction.Hormone Class medicine, instant effect, but easily recur after being discontinued, such as local hydrocortisone class medicine can lead to thinning of skin, produces skin The side effect such as drying, atrophy, telangiectasis, pigmentation, even more serious person may produce hypothalamic-pituitary-adrenal Unsuitable heavy dose of, the large area life-time service of the suppression of axle.Therefore effective, no hormone, the treatment having no toxic side effect is developed in urgent clinical needs Psoriasic medicine.
Content of the invention
It is an object of the invention to invent a kind of antipsoriatics thing, the present invention no hormone, nontoxic, have no side effect, Effect substantially, large area can use, trusts safely.
For solving above-mentioned technical problem, the present invention employs the following technical solutions：
One kind treats psoriasic Chinese medicine ointment, and it is to be configured to by the raw material of Chinese medicine of following weight parts：Broussonetia papyrifera juice 10- 14 parts, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preferably, described ointment is to be configured to by the raw material of Chinese medicine of following weight parts：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preferably, described ointment is to be configured to by the raw material of Chinese medicine of following weight parts：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preferably, described ointment is to be configured to by the raw material of Chinese medicine of following weight parts：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
A kind of preparation method treating psoriasic Chinese medicine ointment it is characterised in that：Comprise the following steps,
1) weigh following weight parts raw material：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part；
2) take Radix Arnebiae (Radix Lithospermi) decontamination to clean, be placed in container, add the distilled water immersion 4-6 hour of 8 times amount, then heating is boiled Boiling 2-3 hour, extracts, and gained extracting solution is concentrated under the conditions of 60 DEG C the thick paste for 1.12-1.26 times, standby；
3) take Indigo Naturaliss to clean to mash, add the distilled water of 4-5 times amount, stir, filter, obtain filtrate standby；
4) take the Fructus Kochiae to go the removal of impurity, be placed in mortar and grind into powder, obtain the fine powder of 200 mesh, standby；
5) Semen sojae atricolor extract：Semen sojae atricolor active compound add in water or the ethanol of 8-10 times of quality, 80-120 DEG C of backflow or super Sound extracts 0.2-6h, collects 3-12 times that extracting solution is concentrated into material quantity, collects extracting solution again, obtains Semen sojae atricolor extract；
6) by above-mentioned steps 2) -5) obtained by thick paste, filtrate and fine powder, Semen sojae atricolor extract mixing, add Broussonetia papyrifera juice, Pine tar and Borneolum Syntheticum, stir, and make finished product and prop up for 12g-20g/, measure, pack, dispatch from the factory.
Using method：1. first clean affected part with warm water, take the Chinese medicine ointment of the appropriate present invention gently to spread, daily 2-3 time, Softly massage to help absorption.Psoriasiss are difficult to clean every time, and the available wet towel wrung out gently wipes；If incrustation is excessive, Can use the vegetable oil after first spreading sterilization, gently wiped with wet towel again within second day, crust is just easier to be removed, afterwards again Chinese medicine ointment using the present invention；General psoriasiss can be cured using 20-30 days, and severe psoriasiss 30-40 days can be cured.
Compared with prior art, the invention has the beneficial effects as follows：
The present invention has selected Chinese crude drug as treating psoriasic raw material, simultaneously dry from strengthening the body resistance, heat-clearing and toxic substances removing, heat clearing away The fast efficacy such as wet, wind-dispelling removing toxic substances, dispelling wind for relieving itching are started with, and comprehensive determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, thus eliminate the factor that psoriasiss cause, comprehensively Adjust psorasis area position.No hormone, nontoxic, have no side effect, trusted using safety.
Specific embodiment
With reference to embodiment, the present invention is further illustrated.Embodiments of the present invention are including but not limited to following Embodiment.
[embodiment 1]
Raw material：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 Part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preparation：
1) weigh following weight parts raw material：10 parts of Broussonetia papyrifera juice, 10 parts of pine tar, 10 parts of the Fructus Kochiae, 15 parts of Radix Arnebiae (Radix Lithospermi), Indigo Naturaliss 10 Part, 5 parts of Semen sojae atricolor extract, 3 parts of Borneolum Syntheticum；
2) take Radix Arnebiae (Radix Lithospermi) decontamination to clean, be placed in container, add the distilled water immersion 4-6 hour of 8 times amount, then heating is boiled Boiling 2-3 hour, extracts, and gained extracting solution is concentrated under the conditions of 60 DEG C the thick paste for 1.12-1.26 times, standby；
3) take Indigo Naturaliss to clean to mash, add the distilled water of 4-5 times amount, stir, filter, obtain filtrate standby；
4) take the Fructus Kochiae to go the removal of impurity, be placed in mortar and grind into powder, obtain the fine powder of 200 mesh, standby；
5) Semen sojae atricolor extract：Semen sojae atricolor active compound add in water or the ethanol of 8-10 times of quality, 80-120 DEG C of backflow or super Sound extracts 0.2-6h, collects 3-12 times that extracting solution is concentrated into material quantity, collects extracting solution again, obtains Semen sojae atricolor extract；
6) by above-mentioned steps 2) -5) obtained by thick paste, filtrate and fine powder, Semen sojae atricolor extract mixing, add Broussonetia papyrifera juice, Pine tar and Borneolum Syntheticum, stir, and make finished product and prop up for 12g-20g/, measure, pack, dispatch from the factory.
[embodiment 2]
Raw material：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 Part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preparation：
1) weigh following weight parts raw material：14 parts of Broussonetia papyrifera juice, 15 parts of pine tar, 15 parts of the Fructus Kochiae, 20 parts of Radix Arnebiae (Radix Lithospermi), Indigo Naturaliss 15 Part, 8 parts of Semen sojae atricolor extract, 8 parts of Borneolum Syntheticum；
2) take Radix Arnebiae (Radix Lithospermi) decontamination to clean, be placed in container, add the distilled water immersion 4-6 hour of 8 times amount, then heating is boiled Boiling 2-3 hour, extracts, and gained extracting solution is concentrated under the conditions of 60 DEG C the thick paste for 1.12-1.26 times, standby；
3) take Indigo Naturaliss to clean to mash, add the distilled water of 4-5 times amount, stir, filter, obtain filtrate standby；
4) take the Fructus Kochiae to go the removal of impurity, be placed in mortar and grind into powder, obtain the fine powder of 200 mesh, standby；
5) Semen sojae atricolor extract：Semen sojae atricolor active compound add in water or the ethanol of 8-10 times of quality, 80-120 DEG C of backflow or super Sound extracts 0.2-6h, collects 3-12 times that extracting solution is concentrated into material quantity, collects extracting solution again, obtains Semen sojae atricolor extract；
6) by above-mentioned steps 2) -5) obtained by thick paste, filtrate and fine powder, Semen sojae atricolor extract mixing, add Broussonetia papyrifera juice, Pine tar and Borneolum Syntheticum, stir, and make finished product and prop up for 12g-20g/, measure, pack, dispatch from the factory.
[embodiment 3]
Raw material：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 Part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
Preparation：
1) weigh following weight parts raw material：12 parts of Broussonetia papyrifera juice, 12 parts of pine tar, 12 parts of the Fructus Kochiae, 17 parts of Radix Arnebiae (Radix Lithospermi), Indigo Naturaliss 12 Part, 6 parts of Semen sojae atricolor extract, 5 parts of Borneolum Syntheticum；
2) take Radix Arnebiae (Radix Lithospermi) decontamination to clean, be placed in container, add the distilled water immersion 4-6 hour of 8 times amount, then heating is boiled Boiling 2-3 hour, extracts, and gained extracting solution is concentrated under the conditions of 60 DEG C the thick paste for 1.12-1.26 times, standby；
3) take Indigo Naturaliss to clean to mash, add the distilled water of 4-5 times amount, stir, filter, obtain filtrate standby；
4) take the Fructus Kochiae to go the removal of impurity, be placed in mortar and grind into powder, obtain the fine powder of 200 mesh, standby；
5) Semen sojae atricolor extract：Semen sojae atricolor active compound add in water or the ethanol of 8-10 times of quality, 80-120 DEG C of backflow or super Sound extracts 0.2-6h, collects 3-12 times that extracting solution is concentrated into material quantity, collects extracting solution again, obtains Semen sojae atricolor extract；
6) by above-mentioned steps 2) -5) obtained by thick paste, filtrate and fine powder, Semen sojae atricolor extract mixing, add Broussonetia papyrifera juice, Pine tar and Borneolum Syntheticum, stir, and make finished product and prop up for 12g-20g/, measure, pack, dispatch from the factory.
Model case
Case 1：Man, 40 years old.According to description：Ill 1 year about, erythema, pimple, vesicle, rotten to the corn, knot in face trunk The skin lesion such as crust occur repeatedly.Do not show through multi-treatment effect.Finally select the Chinese medicine ointment of the present invention, after 10 days, erythema Decorporate, white squama comes off, cure completely after the 20th day.
Case 2：Female, 30 years old, begins to use 5 days, daily 2-3 time, erythema redness is decorporated, starts incrustation, white squama takes off Fall；When the 10th day, fresh skin and drops out in the incrustation psoriasiss part that comes off, and cures completely using to the 15th day psoriasiss.
It is embodiments of the invention as mentioned above.The present invention is not limited to above-mentioned embodiment, and anyone should learn The structure change made under the enlightenment of the present invention, every have same or like technical scheme with the present invention, each falls within this Within the protection domain of invention.

Claims (5)

1. one kind treat psoriasic Chinese medicine ointment it is characterised in that：It is to be configured to by the raw material of Chinese medicine of following weight parts： Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part.
2. one kind according to claim 1 treat psoriasic Chinese medicine ointment it is characterised in that：It is by following weight parts Raw material of Chinese medicine be configured to：10 parts of Broussonetia papyrifera juice, 10 parts of pine tar, 10 parts of the Fructus Kochiae, 15 parts of Radix Arnebiae (Radix Lithospermi), 10 parts of Indigo Naturaliss, Semen sojae atricolor carry Take 5 parts of thing, 3 parts of Borneolum Syntheticum.
3. one kind according to claim 1 treat psoriasic Chinese medicine ointment it is characterised in that：It is by following weight parts Raw material of Chinese medicine be configured to：14 parts of Broussonetia papyrifera juice, 15 parts of pine tar, 15 parts of the Fructus Kochiae, 20 parts of Radix Arnebiae (Radix Lithospermi), 15 parts of Indigo Naturaliss, Semen sojae atricolor carry Take 8 parts of thing, 8 parts of Borneolum Syntheticum.
4. one kind according to claim 1 treat psoriasic Chinese medicine ointment it is characterised in that：It is by following weight parts Raw material of Chinese medicine be configured to：12 parts of Broussonetia papyrifera juice, 12 parts of pine tar, 12 parts of the Fructus Kochiae, 17 parts of Radix Arnebiae (Radix Lithospermi), 12 parts of Indigo Naturaliss, Semen sojae atricolor carry Take 6 parts of thing, 5 parts of Borneolum Syntheticum.
5. a kind of preparation method treating psoriasic Chinese medicine ointment according to claim 1-4 it is characterised in that：Including Following steps,
1) weigh following weight parts raw material：Broussonetia papyrifera juice 10-14 part, pine tar 10-15 part, Fructus Kochiae 10-15 part, Radix Arnebiae (Radix Lithospermi) 15-20 Part, Indigo Naturaliss 10-15 part, Semen sojae atricolor extract 5-8 part, Borneolum Syntheticum 3-8 part；
2) take Radix Arnebiae (Radix Lithospermi) decontamination to clean, be placed in container, add the distilled water immersion 4-6 hour of 8 times amount, then heated and boiled 2- 3 hours, extract, and gained extracting solution is concentrated under the conditions of 60 DEG C the thick paste for 1.12-1.26 times, standby；
3) take Indigo Naturaliss to clean to mash, add the distilled water of 4-5 times amount, stir, filter, obtain filtrate standby；
4) take the Fructus Kochiae to go the removal of impurity, be placed in mortar and grind into powder, obtain the fine powder of 200 mesh, standby；
5) Semen sojae atricolor extract：Semen sojae atricolor active compound adds in the water of 8-10 times of quality or ethanol, 80-120 DEG C of backflow or ultrasonic carry Take 0.2-6h, collect 3-12 times that extracting solution is concentrated into material quantity, collect extracting solution again, obtain Semen sojae atricolor extract；
6) by above-mentioned steps 2) -5) obtained by thick paste, filtrate and fine powder, Semen sojae atricolor extract mixing, add Broussonetia papyrifera juice, pine to evaporate Oil and Borneolum Syntheticum, stir, make finished product and prop up for 12g-20g/, measure, pack, dispatch from the factory.
CN201611008917.1A 2016-11-16 2016-11-16 Traditional Chinese medicine unguent for treating psoriasis and preparing method thereof Pending CN106420930A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102233085A (en) * 2010-10-01 2011-11-09 刘叙光 External application drug for treating skin diseases
CN104096010A (en) * 2014-04-14 2014-10-15 四川金堂海纳生物医药技术研究所 Ointment medicine for treatment of dermatopathy and preparation method thereof
CN104800346A (en) * 2015-04-27 2015-07-29 奚济孝 Traditional Chinese medicine ointment for treating infantile eczema

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102233085A (en) * 2010-10-01 2011-11-09 刘叙光 External application drug for treating skin diseases
CN104096010A (en) * 2014-04-14 2014-10-15 四川金堂海纳生物医药技术研究所 Ointment medicine for treatment of dermatopathy and preparation method thereof
CN104800346A (en) * 2015-04-27 2015-07-29 奚济孝 Traditional Chinese medicine ointment for treating infantile eczema

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