CN106418069A - Beverage having efficacies of neutralizing effect of alcoholic drinks and protecting liver - Google Patents

Beverage having efficacies of neutralizing effect of alcoholic drinks and protecting liver Download PDF

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Publication number
CN106418069A
CN106418069A CN201610816175.9A CN201610816175A CN106418069A CN 106418069 A CN106418069 A CN 106418069A CN 201610816175 A CN201610816175 A CN 201610816175A CN 106418069 A CN106418069 A CN 106418069A
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CN
China
Prior art keywords
parts
beverage
liver
polysaccharide
malic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610816175.9A
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Chinese (zh)
Inventor
张培红
张可池
Original Assignee
Fujian Trillion Ecommerce Co Ltd Of Shop-Within-A-Shop
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Application filed by Fujian Trillion Ecommerce Co Ltd Of Shop-Within-A-Shop filed Critical Fujian Trillion Ecommerce Co Ltd Of Shop-Within-A-Shop
Priority to CN201610816175.9A priority Critical patent/CN106418069A/en
Publication of CN106418069A publication Critical patent/CN106418069A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention provides a beverage having efficacies of neutralizing the effect of alcoholic drinks and protecting the liver. The beverage is made from the main raw materials in parts by weight: 10-15 parts of Yulangsan polysaccharides, 8-15 parts of astragalus polysaccharide, 8-15 parts of lentinan, 8-13 parts of cypress mushroom polysaccharide, 8-12 parts of glossy ganoderma polysaccharides, 5-10 parts of Chinese wolfberry fruit polysaccharides, 10-18 parts of malic acid, 10-15 parts of honey, 1-3 parts of vitamin E, 0.1-0.2 part of lactic acid and 100-150 parts of pure water. The beverage produced according to a formula of the beverage disclosed by the invention can quickly reduce ethanol concentration in serum, can improve the alcohol dehydrogenase activity of liver tissue and stomach tissue, can significantly reduce AST activity and ALT activity in the serum, can have the effect of protecting the liver, can significantly improve the SOD vitality and the CAT vitality in liver tissue, and can have the effects of restraining a lipid peroxidation reaction and antioxidation, so that the oxidative damage of acute alcoholism can be alleviated through regulating and improving free radical metabolism.

Description

A kind of beverage with Antialcoholic liver-protecting effect
Technical field
The invention belongs to food technology field is and in particular to a kind of beverage with Antialcoholic liver-protecting effect.
Background technology
Ethanol quickly enters blood from gastrointestinal absorption, can 100% be absorbed in two hours.Liver is metabolism ethanol Major organs, ethanol dehydrogenase in liver for the ethanol(ADH)It is catalyzed and generates acetaldehyde, acetaldehyde is through the second in liver mitochondrion Aldehyde dehydrogenase(ALDH)It is further oxidized to nontoxic acetic acid, ultimately generate carbon dioxide and energy.
The commonly used decomposing alcohol of current antialcoholic drug plays the effect relieved the effect of alcohol, and dispelling effects of alcohol is slow, can only alleviate human body The symptom that interior alcohol concentration is too high and leads to human body discomfort, but there is no health-care effect to the lesions of liver and kidney that ethanol causes.Ethanol After liver metabolism, unwanted metabolic products such as acetaldehyde can be produced, if do not accelerated metabolism, the excretion of acetaldehyde, can lead to more serious Kidney injury, simultaneously in order to improve dispelling effects of alcohol, existing antialcoholic drug usually adds chemical addition agent to improve the solution of antialcoholic drug Wine effect, chemical addition agent, typically through liver metabolism, through renal excretion, is eaten for a long time a large amount of food adding chemical addition agent, Become the hidden danger of health.Additionally, antialcoholic drug almost cannot alleviate the dizzy, weak, absent minded etc. of generation of drinking Symptom, so need to focus on hepatoprotective resisting fatigue when modern white collar is drunk, could not affect just in the liver protecting afterwards drunk and Normal work and study.
Dry root of Millettia pulchra(Dunn)Kurz var.laxior(Dunn)Z.Wei, Yulangsan polysaccharide can postpone the drunk time, also can reduce AST in drunk mouse liver, The activity of ALT, MDA, increases ADH and SOD activity, illustrates that Yulangsan polysaccharide has liver protection to be attenuated, acute alcoholism is had substantially Effects of relieving alcoholism and protecting liver.
Experimentation shows, edible fungi polysaccharide mycelium has the function that minimizing Alcoholic injures, edible fungi polysaccharide to liver Though macromolecular substances, remain to enter blood by mucosa, since blood circulation can be entered just can reach cell.
The resisting fatigue of malic acid, hepatoprotective, kidney, key role, L MALIC ACID can promote ammonia metabolism, reduces ammonia concentration, There is protective effect to liver.
Content of the invention
It is an object of the invention to provide a kind of beverage with Antialcoholic liver-protecting effect, the formula according to the present invention is produced The beverage coming can quickly reduce concentration of ethanol in serum, improve liver, gastric tissue alcohol dehydrogenase activity, and can significantly reduce serum Middle AST, ALT activity, has protective effect to liver, can significantly improve SOD, CAT vigor in hepatic tissue, has suppression lipid mistake Oxidation reaction, antioxidation, thus by adjusting and improving Radical Metabolism, mitigating the oxidative damage of acute alcoholism, The symptoms such as drunk rear gastrointestinal upset, dizziness, headache can be alleviated simultaneously, and liver is served with certain protective effect.
For achieving the above object, the present invention adopts the following technical scheme that:
A kind of beverage with Antialcoholic liver-protecting effect, the primary raw material of described beverage includes by weight:Yulangsan polysaccharide 10- 15 parts, astragalus polysaccharidess 8-15 part, lentinan 8-15 part, cypress granulose 8-13 part, ganoderan 8-12 part, lycium barbarum polysaccharide 5- 10 parts, malic acid 10-18 part, Mel 10-15 part, Vitamin E 1-3 part, lactic acid 0.1-0.2 part, pure water 100-150 part.
Preferably, the primary raw material of described beverage includes by weight:Yulangsan polysaccharide 10-13 part, astragalus polysaccharidess 10- 13 parts, lentinan 10-12 part, cypress granulose 8-10 part, ganoderan 8-10 part, lycium barbarum polysaccharide 8-10 part, malic acid 10- 15 parts, Mel 10-12 part, Vitamin E 1-3 part, lactic acid 0.1-0.2 part, pure water 100-150 part.
Preferably, the primary raw material of described beverage includes by weight:13 parts of Yulangsan polysaccharide, 10 parts of astragalus polysaccharidess, 10 parts of lentinan, 9 parts of cypress granulose, 9 parts of ganoderan, 8 parts of lycium barbarum polysaccharide, 15 parts of malic acid, 12 parts of Mel, vitamin 2 parts of E, 0.2 part of lactic acid, 100 parts of pure water.
Described malic acid is L MALIC ACID.
The remarkable advantage of the present invention:
Yulangsan polysaccharide can postpone to occur the drunk time, also can reduce the activity of AST, ALT, MDA in drunk mouse liver, Increase ADH and SOD activity, illustrate that Yulangsan polysaccharide has liver protection to be attenuated, have obvious effects of relieving alcoholism and protecting liver to acute alcoholism.
Lentinan, cypress granulose, ganoderan, can enter blood by mucosa, reached thin by blood circulation Born of the same parents, can play the effect quickly relieved the effect of alcohol.AST, ALT activity in serum can be significantly reduced, to liver, there is protective effect, can show Write and improve SOD, CAT vigor in hepatic tissue, there is anti-lipid peroxidation reaction, antioxidation, thus by regulation and changing Kind Radical Metabolism, mitigates the oxidative damage of acute alcoholism.
Vitamin E can promote cell metabolism, promote lipid metabolism, reduction blood fat, suppression cholesterol generation and Arteriosclerosis.
L MALIC ACID can promote ammonia metabolism, reduce ammonia concentration, have protective effect to liver, also have the work(of resisting fatigue Effect.
Astragalus polysaccharidess have expansion of blood vessels and Dilation of coronary artery, have obvious anti-fatigue effect, astragalus polysaccharidess are to experiment Property hepatic injury have a significant protective effect, improve superoxide dismutase(SOD)Active and hepatocellular vigor.
The beverage with Antialcoholic liver-protecting effect of the present invention can quickly reduce concentration of ethanol in serum, improves liver, gastric tissue Alcohol dehydrogenase activity, and AST, ALT activity in serum can be significantly reduced, to liver, there is protective effect, liver can be significantly improved SOD, CAT vigor in tissue, has anti-lipid peroxidation reaction, antioxidation, thus by regulation and improving free radical Metabolism, mitigates the oxidative damage of acute alcoholism, can alleviate the symptoms such as drunk rear gastrointestinal upset, dizziness, headache simultaneously, and Liver is served with certain protective effect.
Present invention lycium barbarum polysaccharide coordinate Yulangsan polysaccharide, astragalus polysaccharidess, lentinan, cypress granulose, ganoderan, Malic acid, Mel and Vitamin E, have significant Antialcoholic liver-protecting effect.
Specific embodiment
In order that content of the present invention easily facilitates understanding, with reference to specific embodiment to of the present invention Technical scheme is described further, but the present invention is not limited only to this.
Embodiment 1
A kind of beverage with Antialcoholic liver-protecting effect is it is preferred that the primary raw material of described beverage includes by weight:Dry root of Millettia pulchra(Dunn)Kurz var.laxior(Dunn)Z.Wei 13 parts of polysaccharide, 10 parts of astragalus polysaccharidess, 10 parts of lentinan, 9 parts of cypress granulose, 9 parts of ganoderan, 8 parts of lycium barbarum polysaccharide, Fructus Mali pumilae 15 parts of acid, 12 parts of Mel, 2 parts of Vitamin E, 0.2 part of lactic acid, 100 parts of pure water.
Described malic acid is L MALIC ACID.
Routinely technique makes beverage.
Embodiment 2
A kind of beverage with Antialcoholic liver-protecting effect, the primary raw material of described beverage includes by weight:Yulangsan polysaccharide 10 Part, 8 parts of astragalus polysaccharidess, 8 parts of lentinan, 8 parts of cypress granulose, 8 parts of ganoderan, 5 parts of lycium barbarum polysaccharide, 10 parts of malic acid, 10 parts of Mel, 1 part of Vitamin E, 0.1 part of lactic acid, 100 parts of pure water.
Described malic acid is L MALIC ACID.
Routinely technique makes beverage.
Embodiment 3
A kind of beverage with Antialcoholic liver-protecting effect, the primary raw material of described beverage includes by weight:Yulangsan polysaccharide 15 Part, 15 parts of astragalus polysaccharidess, 15 parts of lentinan, 13 parts of cypress granulose, 12 parts of ganoderan, 10 parts of lycium barbarum polysaccharide, malic acid 18 parts, 15 parts of Mel, 3 parts of Vitamin E, 0.2 part of lactic acid, 150 parts of pure water.
Described malic acid is L MALIC ACID.
Routinely technique makes beverage.
Drunk experiment
Mice is divided three groups, every group 10, gavages normal saline respectively(Matched group), common beverage for dispelling alcoholic intoxication(No. 1 group), according to this The beverage (No. 2 groups) that embodiment 1 is obtained, gavaging metering is 0.3ml/10g, gavages Chinese liquor in mice, gavage metering after 30min For 0.15ml/10g, record mice righting reflex loss(Drunk)To recovery(Relieving alcoholic intoxication)Required time, separately continuous with same operation After 7d, after gavaging Chinese liquor 1h, use biochemical colorimetric method for determining concentration of ethanol in serum regulating liver-QI, gastric tissue alcohol dehydrogenase enzyme activity respectively Property.
Table 1 mice drunk is tested
Table 2 concentration of ethanol in serum and liver, gastric tissue ADH measurement result
Result:In drunk experiment, No. 2 group mices are from drinking to righting reflex loss compared with matched group(Drunk)Time bright Aobvious prolongation, the relieving alcoholic intoxication time substantially shortens, and serum ethanol content substantially reduces, and liver stomach function regulating ADH is higher than matched group;And No. 2 groups Effect is better than and No. 1 group.Illustrate that this product has good sober-up function.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent with Modify, all should belong to the covering scope of the present invention.

Claims (4)

1. a kind of beverage with Antialcoholic liver-protecting effect is it is characterised in that the primary raw material of described beverage includes by weight: Yulangsan polysaccharide 10-15 part, astragalus polysaccharidess 8-15 part, lentinan 8-15 part, cypress granulose 8-13 part, ganoderan 8-12 Part, lycium barbarum polysaccharide 5-10 part, malic acid 10-18 part, Mel 10-15 part, Vitamin E 1-3 part, lactic acid 0.1-0.2 part, pure Water 100-150 part.
2. a kind of beverage with Antialcoholic liver-protecting effect according to claim 1 it is characterised in that described beverage main Raw material includes by weight:Yulangsan polysaccharide 10-13 part, astragalus polysaccharidess 10-13 part, lentinan 10-12 part, Cupressaceae bacterium are many Sugared 8-10 part, ganoderan 8-10 part, lycium barbarum polysaccharide 8-10 part, malic acid 10-15 part, Mel 10-12 part, Vitamin E 1-3 Part, lactic acid 0.1-0.2 part, pure water 100-150 part.
3. a kind of beverage with Antialcoholic liver-protecting effect according to claim 1 it is characterised in that described beverage main Raw material includes by weight:13 parts of Yulangsan polysaccharide, 10 parts of astragalus polysaccharidess, 10 parts of lentinan, 9 parts of cypress granulose, spirit 9 parts of sesame polysaccharide, 8 parts of lycium barbarum polysaccharide, 15 parts of malic acid, 12 parts of Mel, 2 parts of Vitamin E, 0.2 part of lactic acid, 100 parts of pure water.
4. a kind of beverage with Antialcoholic liver-protecting effect according to claim 1 or 2 or 3 is it is characterised in that described Fructus Mali pumilae Acid is L MALIC ACID.
CN201610816175.9A 2016-09-12 2016-09-12 Beverage having efficacies of neutralizing effect of alcoholic drinks and protecting liver Pending CN106418069A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110200076A (en) * 2019-07-10 2019-09-06 吉林农业大学 A kind of drink with stomach invigorating antialcoholism function with three kinds of roadside edible wild herbs and fungi polysaccharide mixture
CN110522028A (en) * 2019-09-29 2019-12-03 承德润雨科技有限公司 A kind of composition that protect liver is antifatigue and its application

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874612A (en) * 2009-04-29 2010-11-03 郝帅 Beverage used for dispelling effect of alcohol and protecting liver, and preparation method thereof
CN102309047A (en) * 2010-07-06 2012-01-11 湖南敬和堂制药有限公司 Formula of mung bean-traditional Chinese medicine compound beverage capable of cleansing and protecting liver and preparation technique
CN102309045A (en) * 2011-08-26 2012-01-11 徐州工程学院 Sanluhui drink and manufacture method thereof
CN102894447A (en) * 2012-11-02 2013-01-30 尹新波 Ganoderma lucidum polysaccharide health-care drink and production method thereof
CN103750450A (en) * 2013-12-27 2014-04-30 秦燕 Sargassum fusiforme polysaccharide beverage and preparation method thereof
CN103859514A (en) * 2014-03-24 2014-06-18 浙江宇翔生物科技有限公司 Seaweed polysaccharide beverage
CN103960731A (en) * 2013-01-30 2014-08-06 王玮 Drink containing ornithine aspartate and preparation method thereof
CN105030812A (en) * 2015-06-24 2015-11-11 潘秀娟 Compound fungal polysaccharide capsule
CN105395702A (en) * 2015-12-09 2016-03-16 江苏神华药业有限公司 Composition with hangover alleviating, liver protecting and anti-fatigue efficacy and application thereof

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874612A (en) * 2009-04-29 2010-11-03 郝帅 Beverage used for dispelling effect of alcohol and protecting liver, and preparation method thereof
CN102309047A (en) * 2010-07-06 2012-01-11 湖南敬和堂制药有限公司 Formula of mung bean-traditional Chinese medicine compound beverage capable of cleansing and protecting liver and preparation technique
CN102309045A (en) * 2011-08-26 2012-01-11 徐州工程学院 Sanluhui drink and manufacture method thereof
CN102894447A (en) * 2012-11-02 2013-01-30 尹新波 Ganoderma lucidum polysaccharide health-care drink and production method thereof
CN103960731A (en) * 2013-01-30 2014-08-06 王玮 Drink containing ornithine aspartate and preparation method thereof
CN103750450A (en) * 2013-12-27 2014-04-30 秦燕 Sargassum fusiforme polysaccharide beverage and preparation method thereof
CN103859514A (en) * 2014-03-24 2014-06-18 浙江宇翔生物科技有限公司 Seaweed polysaccharide beverage
CN105030812A (en) * 2015-06-24 2015-11-11 潘秀娟 Compound fungal polysaccharide capsule
CN105395702A (en) * 2015-12-09 2016-03-16 江苏神华药业有限公司 Composition with hangover alleviating, liver protecting and anti-fatigue efficacy and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110200076A (en) * 2019-07-10 2019-09-06 吉林农业大学 A kind of drink with stomach invigorating antialcoholism function with three kinds of roadside edible wild herbs and fungi polysaccharide mixture
CN110522028A (en) * 2019-09-29 2019-12-03 承德润雨科技有限公司 A kind of composition that protect liver is antifatigue and its application

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