CN106417312A - Bactericidal composition containing amisulbrom and metalaxyl-m - Google Patents
Bactericidal composition containing amisulbrom and metalaxyl-m Download PDFInfo
- Publication number
- CN106417312A CN106417312A CN201610818516.6A CN201610818516A CN106417312A CN 106417312 A CN106417312 A CN 106417312A CN 201610818516 A CN201610818516 A CN 201610818516A CN 106417312 A CN106417312 A CN 106417312A
- Authority
- CN
- China
- Prior art keywords
- metalaxyl
- amisulbrom
- bactericidal composition
- agent
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to bactericidal composition. The bactericidal composition comprises active ingredients of amisulbrom and metalaxyl-m in a mass ratio of 100:1-1:100, preferably 15:1-1:15, and the total content of the active ingredients is 10%-80% by mass. The bactericidal composition of can be prepared in forms of wettable powder, water dispersible granules, a suspending agent and a water emulsion. The bactericidal composition has an obvious synergistic effect after being compounded and particularly has a quite good control effect on tobacco black shank and phytophthora infestans.
Description
Technical field
The present invention relates to a kind of bactericidal composition, especially contain the bactericidal composition of amisulbrom and Metalaxyl-M, belong to
In technical field of pesticide.
Background technology
Amisulbrom（Amisulbrom）, it is that a kind of triazolylsulfonamide class of the Nissan Chemical research and development nineties in last century is killed
Microbial inoculum.Chemical name is 3- (the bromo- 6- of 3- fluoro- 2 methyl indole -1- sulfonyl)-N, N- dimethyl -1,2,4- triazole -1- sulphonyl
Amine, molecular formula is C13H13BrFN5O4S2.
This medicament is contact killing type bactericide, and the mechanism of action is bonded to the Qi site on cytochromes compound c1, thus
Suppression fungi breathing and the sprouting of spore.This bactericide has higher work to the vegetable plague being caused by Oomycete and downy mildew
Property.Amisulbrom has certain permeability and good resistance of rainwater washing against ability, and investigation finds, chemicals treatment had after 1 day
50% is impregnated with epidermis, has 80% to be impregnated with epidermis after 8 days.Current research, it is also shown that spraying amisulbrom after bacteria infection, can make
Sick blade cannot form and perfect spore, thus suppressing other positions to cause a disease, it is to avoid crop superinfection germ.
Metalaxyl-M belongs to phenylamide compound, is a kind of efficient, wide spectrum systemic fungicide of low toxicity, low-residual,
English name：Metalaxyl-m, Chinese nickname：N- (2- Methoxyacetyl)-N- (2,6- xylyl)-D-alanine first
Ester, N- (2,6- xylyl)-N- (Methoxyacetyl)-D- alanine methyl esters, No. CAS：70630-17-0, molecular formula：
C15H211NO4, molecular weight：279.3315.
Metalaxyl-M is to the vegetables caused by Pseudoperonospora cubensis, phytophthora germ, rotten mildew fungus, fruit tree, tobacco, oil plant, cotton, grain
Food etc. crop pest have efficiently, the prevention effect of lasting period length.
In the real process of agricultural production, controlling disease is easiest to generate the problem that the generation of disease drug resistance.No
Compounded with active ingredient, be to prevent and treat one of very common method of resistance disease.Pass through a large amount of indoor biometricses through inventor
With the research of field control effectiveness test, find that amisulbrom and Metalaxyl-M are combined applying, have obvious synergistic effect, and
Related with Metalaxyl-M compounding about amisulbrom, at present at home and abroad there is not yet relevant report.
Content of the invention
It is an object of the invention to, propose one kind have synergistic function, can delaying drug resistance, reduce usage amount, anti-
The bactericidal composition imitated.
A kind of bactericidal composition containing amisulbrom and Metalaxyl-M proposed by the present invention it is characterised in that：Described
Bactericidal composition contains active ingredient amisulbrom and active ingredient Metalaxyl-M, and both mass ratioes are 100:1~1:100；
Both mass ratioes are preferably 15:1~1:15.
In the bactericidal composition of the present invention, the content of active ingredient depends on the activity to target disease for this active ingredient,
Compound proportion depending on two kinds of active ingredients and synergistic effect degree.Total matter of active ingredient generally in this bactericidal composition
Amount percentage composition is 2% ~ 90%, preferably 10% ~ 80%.
The bactericidal composition of the present invention, can be processed into any formulation agriculturally allowing, wherein more preferably formulation have can
WP, water dispersible granules, suspending agent, aqueous emulsion.
When bactericidal composition is wettable powder, each constituent mass percentage consists of：Amisulbrom 0.1% ~ 80%, essence
Metalaxyl 0.1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 8%, filler supplement surplus.
For wettable powder, spendable auxiliary agent has：Dispersant be selected from lignosulfonates, alkyl benzene sulfonate calcium salt,
Alkylnaphthalene sulfonate, to one of methoxyl group fatty acyl anilinesulfonic acid, APES, ester APEO or
Multiple；Wetting agent is selected from one or more of silkworm excrement, spaonin powder, pull open powder X；Filler is selected from diatomite, kaolin, swelling
One or more of soil, starch.
When bactericidal composition is water dispersible granules, each constituent mass percentage consists of：Amisulbrom 0.1% ~ 80%, essence
Metalaxyl 0.1% ~ 80%, dispersant 3% ~ 9%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, filler supplement surplus.
For water dispersible granules, spendable auxiliary agent has：Dispersant is selected from polyoxyethylene carboxylate, alkyl phenol polyoxy second
Alkene ether formaldehyde condensation products sulfate, naphthalene sulfonic acid-formaldehyde condensation product, double（Alkyl）Naphthalenesulfonate formaldehyde condensation compound, aryl phenol polyoxy second
One or more of alkene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate；Wetting agent is selected from dodecyl sulphur
One or more of sour sodium, silkworm excrement, neopelex；Disintegrant be selected from citric acid, urea, ammonium sulfate, bentonite,
One or more of aluminium chloride, succinic acid, sodium acid carbonate；Filler is selected from white carbon, attapulgite, precipitated calcium carbonate, kaolinite
One or more of soil, starch.
When bactericidal composition is suspending agent, each constituent mass percentage consists of：Amisulbrom 0.1% ~ 50%, smart first frost
Spirit 0.1% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.1% ~ 1%, thickener 0.1% ~ 2%, antifreezing agent 0.1% ~
8%th, deionized water adds to 100%.
For suspending agent, spendable auxiliary agent has：Dispersant is selected from polycarboxylate, aliphatic amine polyoxyethylene ether, naphthalene sulfonic acids
One or more of formaldehyde condensation products sodium salt；Wetting agent be selected from one of wetting and penetrating agent F, spaonin powder, spaonin powder or
Multiple；Defoamer is selected from C8~10Aliphatic alcohols, organosilicon ketone, C10~20Saturated fat acids（As capric acid）And acid amides, compound
One or more of；Thickener is selected from one of xanthans, aluminium-magnesium silicate, hydroxyethyl cellulose, methylcellulose or many
Kind；Antifreezing agent is selected from one or more of glycerine, propane diols, ethylene glycol；Water is deionized water.
When bactericidal composition is aqueous emulsion, each constituent mass percentage consists of：Amisulbrom 0.1% ~ 50%, smart first frost
Spirit 0.1% ~ 50%, solvent 1% ~ 30%, emulsifying agent 1% ~ 15%, antifreezing agent 0.1% ~ 10%, thickener 0.1% ~ 2%, defoamer 0.01% ~
2%th, deionized water adds to 100%.
For aqueous emulsion, spendable auxiliary agent has：Solvent be selected from DMF, cyclohexanone, methyl alcohol, ethanol,
3-methyl cyclohexanol ketenes, NOP, N- pyrrolidones, propyl alcohol, butanol, ethylene glycol, diethylene glycol, ethylene glycol first
One or more of ether, butyl ether, ethyl acetate, vegetable oil, acetonitrile；Emulsifying agent is selected from alkyl benzene sulfonate calcium salt, styrene gathers
Oxygen vinethene ammonium sulfate, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#,
One of 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80,602#
Or it is multiple；Antifreezing agent is selected from one or more of polyethylene glycol, ethylene glycol, propane diols；Thickener is selected from aluminium-magnesium silicate, hydroxyl first
One or more of base cellulose, xanthans, polyvinyl alcohol；Defoamer is selected from silicone oil, organosilicon ketone, C10~20Saturated fat
Acids（As capric acid）And one or more of acid amides, compound；Water is deionized water.
The bactericidal composition of the present invention, has good prevention effect to black shank, tomato late blight.
Compared with prior art, what the present invention produced has the beneficial effect that：（1）Its activity and bactericidal effect are not that each component is lived
Property simple superposition, compared with existing unitary agent, in addition to having significant bactericidal effect, and have significant synergy to make
With；（2）In bactericidal composition, the mechanism of action of active ingredient is different, is conducive to avoiding developing immunity to drugs, widens simultaneously
Antimicrobial spectrum；（3）Field usage amount reduces, and effectively reduces environmental pollution, reduces residues of pesticides, reduces and produces and use cost.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, present invention specific examples below
Illustrate, but the present invention is limited to absolutely not this.Percentage in embodiment is mass percent.
Implementation of an application example one：The Toxicity Determination test that amisulbrom and Metalaxyl-M compound
The Toxicity Determination to black shank for the toxicity test embodiment 1
Subjects：Black shank( Phytophtora parasitica var.nicotianae Tucker)
Pastille culture medium method：Survey standard method NY/T 1156.2-2006 with reference to raw.
Take the liquid 3mL of each single dose and mixture series concentration, add in the PDA culture medium of 27mL being cooled to 45 DEG C, system
The pastille culture medium flat board of final concentration required for one-tenth.Then, produce 6mm from the culture tobacco black shank bacterium colony edge of 7 days straight
Footpath mycelia block, moves in each series pastille culture medium, mycelia faces down, and each process is repeated 4 times.It is disposed, be placed in 25 DEG C
Constant temperature biochemical cultivation case in cultivate, after 4 days measure colony diameter, calculate growth inhibition ratio.
By the linear regression analysis between the probit value of inhibiting rate and the logarithm value of series concentration, obtain each medicament
EC50Value, calculates the co-toxicity coefficient of mixture with the abundant method of Sun Yun（CTC）, the activity to germ for the reagent agent is evaluated with this.
[blank bacterium colony increases diameter (D to growth inhibition ratio (I) %=0)-chemicals treatment bacterium colony increases diameter (D1)]/empty
White comparison bacterium colony increases diameter (D0)×100
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) × 100
Mixture theoretical toxicity index (the TTI)=medicament A toxicity index × shared percentage in mixture of A medicament (%)+medicament B
The toxicity index × shared percentage in mixture of B medicament (%)
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
Co-toxicity coefficient CTC >=120 of complex preparation show as synergistic effect, and 80 ＜ CTC ＜ 120 show as summation action, and CTC≤
80 show as antagonism.Toxicity Determination result of the test, refers to table 1.
Table 1 amisulbrom and Metalaxyl-M compound the toxicity test result to black shank
Above result of the test shows, amisulbrom and Metalaxyl-M compound preventing and treating black shank, and proportioning is 100:1~1:100
Between when, co-toxicity coefficient, all more than 120, has synergistic effect；And 15:1~1:When between 15, co-toxicity coefficient is above
180, synergistic effect becomes apparent from.
The Toxicity Determination to tomato late blight for the toxicity test embodiment 2
Subjects：Phytophthora infestans germ（Phytophthora infestans(Mont.)de Bary）
Pastille culture medium method：Survey standard method NY/T 1156.2-2006 with reference to raw.
Take the liquid 3mL of each single dose and mixture series concentration, add in the PDA culture medium of 27mL being cooled to 45 DEG C, system
The pastille culture medium flat board of final concentration required for one-tenth.Then, produce 6mm from the culture Phytophthora infestans germ colony edge of 7 days straight
Footpath mycelia block, moves in each series pastille culture medium, mycelia faces down, and each process is repeated 4 times.It is disposed, be placed in 25 DEG C
Constant temperature biochemical cultivation case in cultivate, after 4 days measure colony diameter, calculate growth inhibition ratio.
By the linear regression analysis between the probit value of inhibiting rate and the logarithm value of series concentration, obtain each medicament
EC50Value, calculates the co-toxicity coefficient of mixture with the abundant method of Sun Yun（CTC）, the activity to germ for the reagent agent is evaluated with this.
[blank bacterium colony increases diameter (D to growth inhibition ratio (I) %=0)-chemicals treatment bacterium colony increases diameter (D1)]/empty
White comparison bacterium colony increases diameter (D0)×100
Actual measurement toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) × 100
Mixture theoretical toxicity index (the TTI)=medicament A toxicity index × shared percentage in mixture of A medicament (%)+medicament B
The toxicity index × shared percentage in mixture of B medicament (%)
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
Co-toxicity coefficient CTC >=120 of complex preparation show as synergistic effect, and 80 ＜ CTC ＜ 120 show as summation action, and CTC≤
80 show as antagonism.Toxicity Determination result of the test, refers to table 2.
Table 2 amisulbrom and Metalaxyl-M compound the toxicity test result to tomato late blight
Above result of the test shows, amisulbrom and Metalaxyl-M compound preventing and treating tomato late blight, and proportioning is 100:1~1:100
Between when, co-toxicity coefficient, all more than 120, has synergistic effect；And 15:1~1:When between 15, co-toxicity coefficient is above
180, synergistic effect becomes apparent from.
Implementation of an application example two：Amisulbrom and Metalaxyl-M compound product example of formulations（Following content is folding hundred
Percentage composition）, but the present invention is not limited to the proportion in following examples.
Wettable powder（Example of formulations 1 ~ 3）
This concrete procedure of processing of bactericidal composition wettable powder is：According to above-mentioned formula by active ingredient amisulbrom, essence
Metalaxyl, dispersant, wetting agent, filler mixing, mix in mixed cylinder, remix all after pulverizing through airslide disintegrating mill
Even, you can to make wettable powder of the present invention.
Example of formulations 1 80% amisulbrom Metalaxyl-M wettable powder
Amisulbrom 40%, Metalaxyl-M 40%, lignosulfonates（Dispersant）6%th, silkworm excrement（Wetting agent）6%th, diatomite adds
To 100%, 80% amisulbrom Metalaxyl-M wettable powder is obtained.
Example of formulations 2 64% amisulbrom Metalaxyl-M wettable powder
Amisulbrom 4%, Metalaxyl-M 60%, alkyl benzene sulfonate calcium salt（Dispersant）5%th, spaonin powder（Wetting agent）5%th, kaolinite
Soil adds to 100%, and 64% amisulbrom Metalaxyl-M wettable powder is obtained.
Example of formulations 3 44% amisulbrom Metalaxyl-M wettable powder
Amisulbrom 40%, Metalaxyl-M 4%, alkylnaphthalene sulfonate（Dispersant）5%th, pull open powder X（Wetting agent）4%th, bentonite
Add to 100%, 44% amisulbrom Metalaxyl-M wettable powder is obtained.
Water dispersible granules（Example of formulations 4 ~ 6）
This concrete procedure of processing of bactericidal composition water dispersible granules is：According to above-mentioned formula by active ingredient amisulbrom, essence
Metalaxyl, dispersant, wetting agent, disintegrant, filler mix, and are pulverized with micro jet, through mediating, are subsequently adding
After carrying out in fluidized-bed granulation dryer granulating, be dried, sieving, you can make water dispersible granules of the present invention.
Example of formulations 4 80% amisulbrom Metalaxyl-M water dispersible granules
Amisulbrom 75%, Metalaxyl-M 5%, polyoxyethylene carboxylate（Dispersant）6%th, lauryl sodium sulfate（Wetting
Agent）6%th, citric acid（Disintegrant）5%th, white carbon adds to 100%, and 80% amisulbrom Metalaxyl-M water dispersible granules are obtained.
Example of formulations 5 60% amisulbrom Metalaxyl-M water dispersible granules
Amisulbrom 30%, Metalaxyl-M 30%, APES formaldehyde condensation products sulfat（Dispersant）6%th, silkworm excrement
（Wetting agent）6%th, urea（Disintegrant）5%th, attapulgite adds to 100%, and 60% amisulbrom Metalaxyl-M water-dispersible grain is obtained
Agent.
Example of formulations 6 22% amisulbrom Metalaxyl-M water dispersible granules
Amisulbrom 2%, Metalaxyl-M 20%, naphthalene sulfonic acid-formaldehyde condensation product（Dispersant）5%th, neopelex（Wetting
Agent）5%th, ammonium sulfate（Disintegrant）5%th, precipitated calcium carbonate adds to 100%, and 22% amisulbrom Metalaxyl-M water-dispersible grain is obtained
Agent.
Suspending agent（Example of formulations 7 ~ 9）
This concrete procedure of processing of bactericidal composition suspending agent is：According to above-mentioned formula by dispersant, wetting agent, defoamer, thickening
Agent, antifreezing agent mix through high speed shear, add active ingredient amisulbrom, Metalaxyl-M, ball in ball mill
Mill 2 ~ 3 hours, makes diameter of particle all below 5 μm, you can to make suspending agent of the present invention.
Example of formulations 7 25.5% amisulbrom Metalaxyl-M suspending agent
Amisulbrom 25%, Metalaxyl-M 0.5%, polycarboxylate（Dispersant）4%th, wetting and penetrating agent F（Wetting agent）4%、C8~10
Aliphatic alcohols（Defoamer）0.5%th, xanthans（Thickener）0.1%th, glycerine（Antifreezing agent）4%th, deionized water adds to 100%, system
Obtain 25.5% amisulbrom Metalaxyl-M suspending agent.
Example of formulations 8 22% amisulbrom Metalaxyl-M suspending agent
Amisulbrom 20%, Metalaxyl-M 2%, aliphatic amine polyoxyethylene ether（Dispersant）4%th, spaonin powder（Wetting agent）3%、C8~10
Aliphatic alcohols（Defoamer）0.4%th, aluminium-magnesium silicate（Thickener）0.3%th, propane diols（Antifreezing agent）5%th, deionized water adds to 100%,
22% amisulbrom Metalaxyl-M suspending agent is obtained.
Example of formulations 9 10.1% amisulbrom Metalaxyl-M suspending agent
Amisulbrom 0.1%, Metalaxyl-M 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt（Dispersant）3%th, spaonin powder（Wetting
Agent）3%th, organosilicon ketone（Defoamer）0.5%th, hydroxyethyl cellulose（Thickener）0.4%th, ethylene glycol（Antifreezing agent）6%th, deionization
Water adds to 100%, and 10.1% amisulbrom Metalaxyl-M suspending agent is obtained.
Aqueous emulsion（Example of formulations 10 ~ 12）
This concrete procedure of processing of bactericidal composition aqueous emulsion is：Will be white to active ingredient amisulbrom, smart first according to above-mentioned formula
Spirit, solvent, emulsifying agent are added together, and make to be dissolved into homogeneous oil phase；Part water, antifreezing agent, defoamer are mixed into equal
Even aqueous phase；While high-speed stirred, oil phase being added aqueous phase in a kettle., add thickener, slowly adding water until reaching specially
Phase point, opens cutter and carries out high speed shear, and add remaining water, shearing about half an hour, forms the aqueous emulsion of oil-in-water type.
It is aqueous emulsion of the present invention.
Example of formulations 10 32% amisulbrom Metalaxyl-M aqueous emulsion
Amisulbrom 2%, Metalaxyl-M 30%, EGME（Solvent）15%、600#（Emulsifying agent）10%th, polyethylene glycol（Anti-
Freeze agent）0.5%th, aluminium-magnesium silicate（Thickener）0.3%th, silicone oil（Defoamer）0.5%th, deionized water adds to 100%, and 32 % indazoles are obtained
Flusulfamide Metalaxyl-M aqueous emulsion.
Example of formulations 11 20.2% amisulbrom Metalaxyl-M aqueous emulsion
Amisulbrom 20%, Metalaxyl-M 0.2%, DMF（Solvent）10%th, alkyl benzene sulfonate calcium salt（Emulsification
Agent）6%th, ethylene glycol（Antifreezing agent）0.3%th, hydroxymethyl cellulose（Thickener）0.3%th, organosilicon ketone（Defoamer）0.2%th, go from
Sub- water adds to 100%, and 20.2% amisulbrom Metalaxyl-M aqueous emulsion is obtained.
Example of formulations 12 10.2% amisulbrom Metalaxyl-M aqueous emulsion
Amisulbrom 0.2%, Metalaxyl-M 10%, ethyl acetate（Solvent）5%th, castor oil polyoxyethylene ether（Emulsifying agent）4%th, third
Glycol（Antifreezing agent）0.5%th, xanthans（Thickener）0.3%、C10~20Saturated fat acids（Defoamer）0.2%th, deionized water adds to
100%, 10.2% amisulbrom Metalaxyl-M aqueous emulsion is obtained.
Implementation of an application example three：The field control effectiveness test that amisulbrom is compounded with Metalaxyl-M
Field information embodiment 1 prevents and treats the field control effectiveness test of black shank
This test arrangement, in Yueyang Junshan District, chooses the black shank heavier plot of morbidity throughout the year.Reference《Agricultural chemicals field medicine
Effect test rule（Two）Bactericidal agent for preventing and treating black shank GB/T17980.90-2004》, test medicine, the cell of blank
Process adopts random alignment, plot area 40m2, often process 4 repetitions, processed as blank using equivalent clear water.Administration side
Method is pouring root, starts dispenser in black shank early stage, whole breeding time dispenser 3 times, 7 ~ 10 days dispenser intervals.
Investigation and statistical method：Every cell adopts five point sampling to investigate, and every takes 5 plants ~ 10 plants, record investigation total strain number
And diseased plant number at different levels.Investigate state of an illness radix before dispenser, 7d ~ 14d investigation prevention effect before next dispenser and after last dispenser.
Stage division：
0 grade：Complete stool is anosis；
1 grade：Stem's scab is less than 1/3rd of stem girth, and indivedual blades are wilted；
3 grades：Stem's scab is less than 1/2nd of stem girth, or half is slightly wilting with lower blade, or bottom minority blade goes out
Existing scab；
5 grades：Stem's scab exceedes 1/2nd of stem girth, or blade more than half is slightly wilting；
7 grades：Stem's scab is around stem girth, or 2/3rds is wilting with blade；
9 grades：The whole blade of diseased plant is wilting or withered.
Drug effect metering method：
Disease index=Σ（The disease numbers of sheets at different levels × relative value of series）/（Investigation total number of sheets × 9）×100
Prevention effect（%）=[1-（After disease index/blank district medicine after disease index × treatment region medicine before blank district medicine
Disease index before disease index × treatment region medicine）]×100
Result of the test shows, amisulbrom and Metalaxyl-M preventive effect on preventing and treating black shank are notable, and preventive effect is above
94%；Comparison medicament amisulbrom single dose preventive effect is 74.75%, and Metalaxyl-M single dose preventive effect is 65.61%；It is substantially better than comparison
The preventive effect to black shank for the single dose.In the range of this test dosage, to tobacco safety, have no adverse effects.
Field information embodiment 2 prevents and treats the field control effectiveness test of tomato late blight
This test arrangement, in Yueyang Yueyang County, chooses the tomato late blight heavier plot of morbidity throughout the year.
Reference《Pesticide field efficacy medicine test criterion（One）Bactericidal agent for preventing and treating tomato late blight GB/T17980.31-2000》,
Test medicine, the cell of blank process and adopt random alignment, plot area 30m2, often process 4 repetitions, with equivalent clear water
Process as blank.Application process is spraying, until the positive and negative of blade uniformly squirts.In tomato late blight early stage
Start dispenser, whole breeding time dispenser 2 times, 7 ~ 10 days dispenser intervals.
Investigation and statistical method：Often the random 5 points of samplings of cell, often click two plants, and every plant point of upper, middle and lower investigate 10
Leaf, to be classified with the percentage that the lesion area on often a piece of leaf accounts for whole leaf area.State of an illness radix is investigated before dispenser, last
Secondary investigation is carried out for 7 ~ 10 days after last dispenser.
Stage division：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of whole leaf area；
3 grades：Lesion area accounts for the 6% ~ 10% of whole leaf area；
5 grades：Lesion area accounts for the 11% ~ 20% of whole leaf area；
7 grades：Lesion area accounts for the 21% ~ 50% of whole leaf area；
9 grades：Lesion area accounts for more than the 50% of whole leaf area.
Drug effect metering method：
Disease index=Σ（The disease numbers of sheets at different levels × relative value of series）/（Investigation total number of sheets × 9）×100
Prevention effect（%）=[1-（After disease index/blank district medicine after disease index × treatment region medicine before blank district medicine
Disease index before disease index × treatment region medicine）]×100
Result of the test shows, amisulbrom and Metalaxyl-M preventive effect on preventing and treating tomato late blight are notable, and preventive effect is above
96%；Comparison medicament amisulbrom single dose preventive effect is 72.47%, Metalaxyl-M single dose preventive effect is 67.02%；It is substantially better than comparison
The preventive effect to tomato late blight for the single dose.In the range of this test dosage, to tomato safety, have no adverse effects.
Bright through the table of field test results of different places throughout the country afterwards, bactericidal composition indazole of the present invention
Flusulfamide and Metalaxyl-M compound, and not only have significant synergistic effect to black shank, tomato late blight, simultaneously to cucumber cream
Mildew, capsicum epidemic disease, the late blight of potato, downy mildew of garpe, celery cabbage clubroot etc. also have preferable prevention effect, and preventive effect
All more than 90%, better than single dose preventive effect, synergy is obvious.
Claims (5)
1. a kind of bactericidal composition containing amisulbrom and Metalaxyl-M it is characterised in that：Described bactericidal composition contains
Active ingredient amisulbrom and active ingredient Metalaxyl-M, both mass ratioes are 100:1~1:100.
2. bactericidal composition according to claim 1 it is characterised in that：Active ingredient amisulbrom and active ingredient essence
Metalaxyl, both mass ratioes are preferably 15:1~1:15.
3. bactericidal composition according to any one of claim 1 to 2 it is characterised in that：Effectively become in bactericidal composition
The gross mass percentage composition dividing is 10% ~ 80%.
4. bactericidal composition according to claim 3 it is characterised in that：Composition can be made into wettable powder, moisture dissipates
Granula, suspending agent, aqueous emulsion.
5. bactericidal composition according to claim 4 has good prevention effect to black shank, tomato late blight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818516.6A CN106417312A (en) | 2016-09-13 | 2016-09-13 | Bactericidal composition containing amisulbrom and metalaxyl-m |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818516.6A CN106417312A (en) | 2016-09-13 | 2016-09-13 | Bactericidal composition containing amisulbrom and metalaxyl-m |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106417312A true CN106417312A (en) | 2017-02-22 |
Family
ID=58168644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610818516.6A Pending CN106417312A (en) | 2016-09-13 | 2016-09-13 | Bactericidal composition containing amisulbrom and metalaxyl-m |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106417312A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007308375A (en) * | 2005-06-01 | 2007-11-29 | Nissan Chem Ind Ltd | Labor saving method for application of agrochemical |
| JP2010150230A (en) * | 2008-05-09 | 2010-07-08 | Nissan Chem Ind Ltd | Germicidal composition |
| CN104738066A (en) * | 2013-12-26 | 2015-07-01 | 山东康乔生物科技有限公司 | Sterilization composition |
| EP2893808A1 (en) * | 2012-09-06 | 2015-07-15 | Nippon Soda Co., Ltd. | Plant growth accelerator |
-
2016
- 2016-09-13 CN CN201610818516.6A patent/CN106417312A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007308375A (en) * | 2005-06-01 | 2007-11-29 | Nissan Chem Ind Ltd | Labor saving method for application of agrochemical |
| JP2010150230A (en) * | 2008-05-09 | 2010-07-08 | Nissan Chem Ind Ltd | Germicidal composition |
| EP2893808A1 (en) * | 2012-09-06 | 2015-07-15 | Nippon Soda Co., Ltd. | Plant growth accelerator |
| CN104738066A (en) * | 2013-12-26 | 2015-07-01 | 山东康乔生物科技有限公司 | Sterilization composition |
Non-Patent Citations (1)
| Title |
|---|
| 徐映明: "《新世纪农药新品种应用手册》", 31 January 2016 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102318627A (en) | A kind of innovative efficient bactericidal composite | |
| CN102318607A (en) | Complexly-formulated high-efficient germicidal composition | |
| CN102349514A (en) | Bupirimate-containing antibacterial composition | |
| CN102239865A (en) | Sterilization composite containing pyraclostrobin and propiconazole | |
| CN102308825A (en) | Germicide composition in combination with bupirimate | |
| CN103081933A (en) | Bactericidal composition containing pyraclostrobin and fluxapyroxad | |
| CN104738066A (en) | Sterilization composition | |
| CN103168780A (en) | Bactericidal composition containing fluopicolide and metrafenone | |
| CN102239864A (en) | Bactericidal composition containing pyraclostrobin and dimethomorph | |
| CN107114370A (en) | A kind of composition pesticide containing S-Ethyl ethylthio sulfonate and bromothalonil | |
| CN107439551A (en) | Bactericidal composition containing kasugarnycin and copper rosinate | |
| CN103125508A (en) | Bactericidal composition containing fluopicolide and benthiavalicarb-isopropyl | |
| CN104054712B (en) | Sterilization composition containing boscalid | |
| CN105475317A (en) | Sterilization combination containing efficient metalaxyl-M and cymoxanil | |
| CN102308804A (en) | Sterilization composition | |
| CN103329904B (en) | Sterilization composition containing bupirimate and ningnanmycin as well as application of sterilization composition | |
| CN102246760A (en) | Bactericidal composition containing fluopicolide and metalaxyl | |
| CN102293200B (en) | Sterilization composition containing zoxamide and copper pimaric acid | |
| CN102007929B (en) | Thifluzamide-containing bactericidal composition | |
| CN104886122B (en) | Compound composition containing dufulin and pyrazole amide bactericide and bactericide | |
| CN102273475A (en) | High efficiency germicide composition | |
| CN102077831A (en) | Sterilizing composition containing thifluzamide and ethylenebisdithiocarbomate | |
| CN106577680A (en) | Bactericide and application thereof | |
| CN102349523A (en) | High-efficient sterilization composition containing bupirimate | |
| CN106417312A (en) | Bactericidal composition containing amisulbrom and metalaxyl-m |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |
|
| RJ01 | Rejection of invention patent application after publication |