CN106415274A - 基于代谢物组的血液样本质量的测定方法和手段 - Google Patents

基于代谢物组的血液样本质量的测定方法和手段 Download PDF

Info

Publication number
CN106415274A
CN106415274A CN201580027673.9A CN201580027673A CN106415274A CN 106415274 A CN106415274 A CN 106415274A CN 201580027673 A CN201580027673 A CN 201580027673A CN 106415274 A CN106415274 A CN 106415274A
Authority
CN
China
Prior art keywords
sample
quality
value
blood
label
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580027673.9A
Other languages
English (en)
Chinese (zh)
Inventor
B·卡姆朗格
O·施米茨
B·贝唐
P·沙茨
E·彼得
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metanomics Health GmbH
Original Assignee
Metanomics Health GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metanomics Health GmbH filed Critical Metanomics Health GmbH
Publication of CN106415274A publication Critical patent/CN106415274A/zh
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30Data warehousing; Computing architectures
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201580027673.9A 2014-03-26 2015-03-26 基于代谢物组的血液样本质量的测定方法和手段 Pending CN106415274A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14161766 2014-03-26
EP14161766.2 2014-03-26
PCT/IB2015/052243 WO2015145387A1 (en) 2014-03-26 2015-03-26 Means and methods for determination of quality of blood samples based on metabolite panel

Publications (1)

Publication Number Publication Date
CN106415274A true CN106415274A (zh) 2017-02-15

Family

ID=50433941

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580027673.9A Pending CN106415274A (zh) 2014-03-26 2015-03-26 基于代谢物组的血液样本质量的测定方法和手段

Country Status (9)

Country Link
US (1) US20180217125A1 (https=)
EP (1) EP3123174A4 (https=)
JP (1) JP2017512996A (https=)
KR (1) KR20160146727A (https=)
CN (1) CN106415274A (https=)
AU (1) AU2015237804A1 (https=)
BR (1) BR112016021929A2 (https=)
CA (1) CA2941979A1 (https=)
WO (1) WO2015145387A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107782825A (zh) * 2017-12-01 2018-03-09 武汉迈特维尔生物科技有限公司 一种基于液相色谱检测动物体中小分子代谢物的方法
CN107818329A (zh) * 2017-08-09 2018-03-20 上海交通大学 一种质谱数据分析方法
CN110609139A (zh) * 2018-06-14 2019-12-24 深圳市理邦精密仪器股份有限公司 抗原浓度过量检测方法、装置及存储介质

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017079384A1 (en) 2015-11-04 2017-05-11 Metabolon, Inc. Automated sample quality assessment
EP3628068A4 (en) * 2017-05-02 2020-12-30 Liquid Biosciences, Inc. SYSTEMS AND METHODS FOR DETERMINING THE ATTRIBUTES OF BIOLOGICAL SAMPLES
US20200182862A1 (en) * 2017-06-16 2020-06-11 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Method and apparatus for single tube blood donor screening
JP7192976B2 (ja) * 2019-05-09 2022-12-20 株式会社島津製作所 試料の評価方法、分析方法、劣化試料の検出方法、劣化血漿試料検出用マーカーおよび劣化血清試料検出用マーカー
US12606858B2 (en) * 2019-09-20 2026-04-21 Charité—Universitäetsmedizin Berlin Methods, kits and devices for measuring extracellular pyridine nucleotide
CN110890130B (zh) * 2019-12-03 2022-09-20 大连理工大学 基于多类型关系的生物网络模块标志物识别方法
CN111239283A (zh) * 2020-02-18 2020-06-05 深圳脉图精准技术有限公司 焦谷氨酸作为判断代谢组学血液样本质量的质检指示物的应用
WO2022008802A1 (en) * 2020-07-09 2022-01-13 Helsingin Yliopisto Method for determining amounts of nad metabolites from sample and methods and uses related thereto
JP7600875B2 (ja) * 2021-06-01 2024-12-17 株式会社島津製作所 試料分析装置、試料分析方法、医薬分析装置および医薬分析方法
EP4390378A4 (en) * 2021-08-17 2025-08-13 Riken DEVICE AND METHOD FOR ANALYZING COMPONENTS
CN120142679B (zh) * 2025-05-06 2026-02-17 南方医科大学珠江医院 生物标志物组合物及其在mgmt启动子甲基化检测中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102483416A (zh) * 2009-06-04 2012-05-30 梅坦诺米克斯保健有限公司 诊断前列腺癌的工具和方法
CN103512972A (zh) * 2013-07-29 2014-01-15 上海交通大学 精神分裂症的生物标志物及其使用方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8849577B2 (en) * 2006-09-15 2014-09-30 Metabolon, Inc. Methods of identifying biochemical pathways
WO2010101564A1 (en) * 2009-03-04 2010-09-10 John Wan Collection and assay device for biological fluid
EP2336784B1 (en) * 2009-12-18 2017-08-16 Roche Diagnostics GmbH GDF-15 and/or Troponin T for predicting kidney failure in heart surgery patients
DE112014000822T5 (de) * 2013-02-14 2015-10-29 Metanomics Health Gmbh Mittel und Verfahren zur Beurteilung der Qualität einer biologischen Probe
AU2014368412A1 (en) * 2013-12-20 2016-07-07 Metanomics Health Gmbh Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102483416A (zh) * 2009-06-04 2012-05-30 梅坦诺米克斯保健有限公司 诊断前列腺癌的工具和方法
CN103512972A (zh) * 2013-07-29 2014-01-15 上海交通大学 精神分裂症的生物标志物及其使用方法和应用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHRISTIANE ODDOZE ET AL.: "Stability study of 81 analytes in human whole blood, in serum and in plasma", 《CLINICAL BIOCHEMISTRY》 *
LINSHENG LIU ET AL.: "Differences in metabolite profile between blood plasma and serum", 《ANALYTICAL BIOCHEMISTRY》 *
N. LIAPPIS ET AL.: "Veranderung der Aminosaure-Konzentration im Plasma von ACD-Blutkonserven wahrend der Lagerung // Alteration of Amino Acid Concentrations in Plasma of ACD-Blood during Storage", 《BLUT》 *
PATRIZIA BERNINI ET AL.: "Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks", 《JOURNAL OF BIOMOLECULAR NMR》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107818329A (zh) * 2017-08-09 2018-03-20 上海交通大学 一种质谱数据分析方法
CN107818329B (zh) * 2017-08-09 2023-04-18 亿纳谱(浙江)生物科技有限公司 一种质谱数据分析方法
CN107782825A (zh) * 2017-12-01 2018-03-09 武汉迈特维尔生物科技有限公司 一种基于液相色谱检测动物体中小分子代谢物的方法
CN110609139A (zh) * 2018-06-14 2019-12-24 深圳市理邦精密仪器股份有限公司 抗原浓度过量检测方法、装置及存储介质

Also Published As

Publication number Publication date
BR112016021929A2 (pt) 2017-08-15
WO2015145387A1 (en) 2015-10-01
EP3123174A1 (en) 2017-02-01
JP2017512996A (ja) 2017-05-25
KR20160146727A (ko) 2016-12-21
US20180217125A1 (en) 2018-08-02
AU2015237804A1 (en) 2016-09-22
CA2941979A1 (en) 2015-10-01
EP3123174A4 (en) 2017-12-06

Similar Documents

Publication Publication Date Title
CN106415274A (zh) 基于代谢物组的血液样本质量的测定方法和手段
Picotti et al. Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions
JP6388606B2 (ja) 生物学的サンプルの質を評価するための手段及び方法
CN101438168B (zh) 预测糖尿病的工具和方法
KR101894111B1 (ko) 대상체에서 췌장암을 진단하기 위한 수단 및 방법
CN101443663A (zh) 诊断糖尿病的工具和方法
JP6921132B2 (ja) 肺高血圧症(ph)の診断のためのバイオマーカー
JP2013512444A (ja) 多発性硬化症を診断するための手段及び方法
Dowling et al. Metabolomic and proteomic analysis of breast cancer patient samples suggests that glutamate and 12-HETE in combination with CA15-3 may be useful biomarkers reflecting tumour burden
Asicioglu et al. Development of an ID-LC–MS/MS method using targeted proteomics for quantifying cardiac troponin I in human serum
JP6389184B2 (ja) サンプルにおいて代謝産物疾患バイオマーカーのクリアランス正規化量を決定するための手段及び方法
Plubell et al. Development of highly multiplex targeted proteomics assays in biofluids using the Stellar mass spectrometer
Mann et al. A quantitative investigation of fucosylated serum glycoproteins with application to esophageal adenocarcinoma
JP6421118B2 (ja) 前立腺摘出術後の前立腺癌の再発の診断のための手段および方法
Asicioglu et al. Comparative evaluation of peptide vs. protein-based calibration for quantification of cardiac troponin I using ID-LC-MS/MS
Velstra et al. Detection of pancreatic cancer using serum protein profiling
Kiseleva et al. Plasma preparation to measure FDA-approved protein markers by selected reaction monitoring
EP3175379A1 (en) Means and methods for assessing a quality of a biological sample
Twigg et al. Evaluation of Serum Proteome Sample Preparation Methods to Support Clinical Proteomics Applications
JP2019039915A (ja) 生物学的サンプルの質を評価するための手段及び方法
Hincapie et al. Multi-lectin Affinity Chromatography (M-LAC) Combined with Abundant Protein Depletion for Analysis of Human Plasma in Clinical Proteomics Applications
Liu et al. Use of universal stable isotope labeling by amino acids in cell culture (SILAC)-based selected reaction monitoring (SRM) approach for verification of breast cancer-related protein markers
KR20140060523A (ko) 생식선 독성을 평가하기 위한 수단 및 방법

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170215