CN106414770A - 用于分析体细胞可动因子的方法及其用途 - Google Patents

用于分析体细胞可动因子的方法及其用途 Download PDF

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CN106414770A
CN106414770A CN201580022555.9A CN201580022555A CN106414770A CN 106414770 A CN106414770 A CN 106414770A CN 201580022555 A CN201580022555 A CN 201580022555A CN 106414770 A CN106414770 A CN 106414770A
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nucleic acid
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acid samples
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基斯·布朗
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Capcod Genomics
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iGenomx International Genomics Corp
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CN201580022555.9A 2014-02-27 2015-02-27 用于分析体细胞可动因子的方法及其用途 Pending CN106414770A (zh)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107245529A (zh) * 2017-08-08 2017-10-13 杭州千麦医学检验所有限公司 血液病融合基因筛查方法
CN108384846A (zh) * 2018-02-28 2018-08-10 北京泱深生物信息技术有限公司 C11orf95基因及其表达产物在诊治类风湿性关节炎和骨关节炎方面的应用
CN108588050A (zh) * 2018-05-14 2018-09-28 北京艾克伦医疗科技有限公司 Dna聚合酶以及核酸检测方法和试剂盒
CN114555815A (zh) * 2019-07-30 2022-05-27 大学健康网络 T细胞受体及其使用方法
WO2023179766A1 (zh) * 2022-03-24 2023-09-28 南京传奇生物科技有限公司 制备dna文库和检测逆转录病毒整合位点的方法

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6261500B2 (ja) 2011-07-22 2018-01-17 プレジデント アンド フェローズ オブ ハーバード カレッジ ヌクレアーゼ切断特異性の評価および改善
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA3216609C (en) 2012-08-14 2024-05-14 10X Genomics, Inc. Microcapsule compositions and methods
US10584381B2 (en) 2012-08-14 2020-03-10 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014093676A1 (en) 2012-12-14 2014-06-19 10X Technologies, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
AU2014214682B2 (en) 2013-02-08 2018-07-26 10X Genomics, Inc. Polynucleotide barcode generation
EP4321628B1 (en) 2013-05-23 2025-09-03 The Board of Trustees of the Leland Stanford Junior University Transposition into native chromatin for personal epigenomics
US20180113137A1 (en) * 2013-10-18 2018-04-26 Tcm Biotech International Corp. Method for detecting the quantity of biomarker and identifying disease status
PL3102722T3 (pl) 2014-02-04 2021-03-08 Jumpcode Genomics, Inc. Frakcjonowanie genomu
WO2015157567A1 (en) 2014-04-10 2015-10-15 10X Genomics, Inc. Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
MX2016016904A (es) 2014-06-26 2017-03-27 10X Genomics Inc Analisis de secuencias de acidos nucleicos.
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
CN113249435B (zh) 2014-06-26 2024-09-03 10X基因组学有限公司 分析来自单个细胞或细胞群体的核酸的方法
MX2017005267A (es) 2014-10-29 2017-07-26 10X Genomics Inc Metodos y composiciones para la secuenciacion de acidos nucleicos seleccionados como diana.
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
SG11201705615UA (en) 2015-01-12 2017-08-30 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
BR112017018054A2 (pt) 2015-02-24 2018-07-24 10X Genomics Inc métodos para a cobertura de sequências de ácidos nucleicos direcionadas
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
WO2016138292A1 (en) 2015-02-25 2016-09-01 Igenomx International Genomics Corporation Methods and compositions for in silico long read sequencing
SG11201804086VA (en) 2015-12-04 2018-06-28 10X Genomics Inc Methods and compositions for nucleic acid analysis
US11339427B2 (en) 2016-02-12 2022-05-24 Jumpcode Genomics, Inc. Method for target specific RNA transcription of DNA sequences
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
CN105886645A (zh) * 2016-05-27 2016-08-24 福建爱我健康生物科技有限公司 一种用于评估皮肤抗皱情况的引物和探针及试剂盒
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN110214186B (zh) 2017-01-30 2023-11-24 10X基因组学有限公司 用于基于微滴的单细胞条形编码的方法和系统
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
US10844372B2 (en) 2017-05-26 2020-11-24 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN109526228B (zh) 2017-05-26 2022-11-25 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
EP3954782A1 (en) 2017-11-15 2022-02-16 10X Genomics, Inc. Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
EA202091673A1 (ru) 2018-01-29 2021-02-03 Ст. Джуд Чилдрен'С Рисерч Хоспитал, Инк. Способ амплификации нуклеиновых кислот
CN112004920B (zh) 2018-02-05 2024-08-02 斯坦福大学托管董事会 用于单细胞和集合细胞的多重测量的系统和方法
CN112262218B (zh) 2018-04-06 2024-11-08 10X基因组学有限公司 用于单细胞处理中的质量控制的系统和方法
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
KR102102107B1 (ko) * 2019-05-30 2020-04-20 단국대학교 천안캠퍼스 산학협력단 이동성 유전인자 SINE 선택적 발굴을 위한 HiSeq 시퀀서 기반의 DNA 라이브러리 제작 방법
WO2021042066A1 (en) * 2019-08-30 2021-03-04 Foundation Medicine, Inc. Kmt2a-maml2 fusion molecules and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008134596A2 (en) * 2007-04-25 2008-11-06 John Wayne Cancer Institute Use of methylated or unmethylated line-i dna as a cancer marker
CN102439177A (zh) * 2009-04-02 2012-05-02 弗卢伊蒂格姆公司 用于对目标核酸进行条形码化的多引物扩增方法
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9596098A (en) * 1997-09-29 1999-04-23 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Display technique for identifying line-1 insertion site polymorphisms
CZ20013532A3 (cs) * 1999-04-01 2002-03-13 Mcgill University Nový typ genetického markeru na bázi transpozonu
NZ517641A (en) 1999-09-07 2004-02-27 Decode Genetics Ehf Detection of alterations in a gene by long range PCR using human mobile elements
GB2387173A (en) * 2002-03-05 2003-10-08 Arrow Therapeutics Ltd Transposon
US20060035245A1 (en) * 2004-04-20 2006-02-16 Ason Brandon L Modulators of enzymatic nucleic acid elements mobilization
EP1960541B1 (en) * 2005-11-14 2013-04-24 Keygene N.V. Method for high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites
US9028561B2 (en) * 2009-05-05 2015-05-12 Milliken & Company Bluing composition and method for treating textile articles using the same
US20130315886A1 (en) * 2009-08-05 2013-11-28 Salk Institute For Biological Studies Retroelements and mental disorders and methods of measuring l1 retrotransposition
US20140031250A1 (en) * 2010-10-07 2014-01-30 David Tsai Ting Biomarkers of Cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008134596A2 (en) * 2007-04-25 2008-11-06 John Wayne Cancer Institute Use of methylated or unmethylated line-i dna as a cancer marker
CN102439177A (zh) * 2009-04-02 2012-05-02 弗卢伊蒂格姆公司 用于对目标核酸进行条形码化的多引物扩增方法
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107245529A (zh) * 2017-08-08 2017-10-13 杭州千麦医学检验所有限公司 血液病融合基因筛查方法
CN108384846A (zh) * 2018-02-28 2018-08-10 北京泱深生物信息技术有限公司 C11orf95基因及其表达产物在诊治类风湿性关节炎和骨关节炎方面的应用
CN108384846B (zh) * 2018-02-28 2020-06-16 固安博健生物技术有限公司 C11orf95基因及其表达产物在诊治类风湿性关节炎和骨关节炎方面的应用
CN108588050A (zh) * 2018-05-14 2018-09-28 北京艾克伦医疗科技有限公司 Dna聚合酶以及核酸检测方法和试剂盒
CN114555815A (zh) * 2019-07-30 2022-05-27 大学健康网络 T细胞受体及其使用方法
WO2023179766A1 (zh) * 2022-03-24 2023-09-28 南京传奇生物科技有限公司 制备dna文库和检测逆转录病毒整合位点的方法

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