CN106404982A - Glycosylated hemoglobin analyzer - Google Patents
Glycosylated hemoglobin analyzer Download PDFInfo
- Publication number
- CN106404982A CN106404982A CN201611189085.8A CN201611189085A CN106404982A CN 106404982 A CN106404982 A CN 106404982A CN 201611189085 A CN201611189085 A CN 201611189085A CN 106404982 A CN106404982 A CN 106404982A
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- specimen
- liquid
- pipe
- cavity
- measuring device
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
Abstract
The invention discloses a glycosylated hemoglobin analyzer, which comprises a body, a specimen heating constant-temperature device, a peristaltic pump, an ion-exchange chromatographic column, a pressure intensifier, a colorimetric measuring device and a liquid storage box, wherein two ends of the specimen heating constant-temperature device are provided with end caps; the middles of the end caps are provided with circular grooves; a round through pipe is arranged inside a cylindrical shell of the specimen heating constant-temperature device; a temperature sensor is arranged in the round through pipe; an annular cavity is formed between the round through pipe and the specimen heating constant-temperature device; a spiral heating pipe is arranged in the annular cavity. In a use process of the glycosylated hemoglobin analyzer, heated liquid enters the annular cavity from a second liquid inlet pipe, and afterwards, is subjected to heat exchange with the spiral heating pipe in the annular cavity, so as to heat a specimen in the spiral heating pipe; hot liquid enters the liquid storage box from a liquid return pipe, so as to form a cycle; the spiral heating pipe can be uniformly heated in the annular cavity.
Description
Technical field
The present invention relates to hemoglobin detecting instrument field, specifically a kind of glycolated hemoglobin analysis.
Background technology
At present, the medical analysis instrument of glycolated hemoglobin ion exchange chromatography is including peristaltic pump, ion exchange
Chromatographic column, colorimetric measuring device, it is arranged on drain line end supercharger, waste liquid bottle, when measuring clinical sample, due to sample
Microscopic grains and floccule can be contained with eluent, though after ion exchange column chromatography, still having a small amount of crystallization or wadding
The impurity such as shape thing pass through colorimetric measuring device, drain line and supercharger.
In glycolated hemoglobin analysis, its specimen heating constant-temperature equipment is one of highly important part, marks at present
The spiral-shaped stainless steel tube of this heating constant-temperature equipment, is placed in metal soaking block and lower metal soaking block, thin film electrical heating
Piece is located at below lower metal soaking block, and insulation material is located at the lower section of thin film electric heating sheets, constitutes specimen heating constant-temperature equipment.
Although it can heat to specimen, its thin film electric heating sheets be located at stainless steel tube below (or side), heat energy from
To another side transmission, stainless steel tube non-uniform temperature, asynchronous can be caused, that is, cannot be carried out uniformly heating.
Content of the invention
It is an object of the invention to provide a kind of glycolated hemoglobin analysis, to solve proposition in above-mentioned background technology
Problem.
For achieving the above object, the present invention provides following technical scheme：
A kind of glycolated hemoglobin analysis, including body, specimen heating constant-temperature equipment, peristaltic pump, ion-exchange chromatography
Post, supercharger, colorimetric measuring device and reserving liquid tank, the bottom of described body is laid with multiple supporting legs, on the right side of the upper end of body
It is provided with rack, rack can be placed specimen bag, the upper end of specimen bag is provided with feed tube, feed tube connects to specimen heating
Thermostat, specimen heating constant-temperature equipment connects to peristaltic pump, and peristaltic pump connects ion exchange column by pipeline, and ion is handed over
Change the upper left side that chromatographic column is located at body, the bottom of ion exchange column is provided with colorimetric measuring device, and colorimetric measuring device sets
Left side in body bottom portion；The top of described colorimetric measuring device is connected with discharging tube, and discharging tube connects to supercharger, supercharger
Lower section be provided with waste liquid bottle, the discharging tube between colorimetric measuring device and supercharger is provided with filter, additionally, also setting on discharge opeing official
There is pressure transducer, the transducing signal of pressure transducer is connected to display, and display is located at the outside of body；Described body
Inside is additionally provided with reserving liquid tank, and the inside of reserving liquid tank is provided with electric heater unit, and the upper end of reserving liquid tank is connected with liquid back pipe, reserving liquid tank
Right-hand member is connected with Miniature liquid pump, and Miniature liquid pump is connected with the second feed tube；The two ends of described specimen heating constant-temperature equipment are provided with
End cap, the middle part of end cap is provided with circular groove, is provided with a circular siphunculus inside the cylindrical housings of specimen heating constant-temperature equipment,
It is provided with temperature sensor in circular siphunculus, between circular siphunculus and specimen heating constant-temperature equipment, be formed with the cavity of ring-type, ring-type
Cavity in be provided with helical form heating tube, one end of helical form heating tube connects feed tube, and the left upper portion of the cavity of ring-type sets
There is liquid outlet, liquid outlet is connected with liquid back pipe, the lower right side of the cavity of ring-type is provided with inlet.
As the further scheme of the present invention：The bottom of described supporting leg is provided with rubber blanket.
As the further scheme of the present invention：Second feed tube is connected with the inlet of the cavity of described ring-type.
As the further scheme of the present invention：The outside of described specimen heating constant-temperature equipment is provided with cylindrical housings.
As the present invention further scheme：The two ends of described circle siphunculus are stuck in the circular groove of end cap.
Compared with prior art, the structure of the present invention is simple, easy to use, and during use, heated liquid is from
Two feed tubes enter in the cavity of ring-type, and then the cavity in ring-type carries out heat exchange with helical form heating tube, thus heating
Specimen in helical form heating tube, hydrothermal solution enters in reserving liquid tank from liquid back pipe, thus forming circulation, helical form heating tube is in ring
Can be cooled uniformly in the cavity of shape.
Brief description
Fig. 1 is a kind of structural representation of glycolated hemoglobin analysis.
Fig. 2 is a kind of structural representation of specimen heating constant-temperature equipment in glycolated hemoglobin analysis.
Specific embodiment
With reference to specific embodiment, the technical scheme of this patent is described in more detail.
Refer to Fig. 1-2, a kind of glycolated hemoglobin analysis, including body 1, specimen heating constant-temperature equipment 7, peristaltic pump
10th, ion exchange column 11, supercharger 3, colorimetric measuring device 12 and reserving liquid tank 16, the bottom of described body 1 is laid with
Multiple supporting legs 19, the height of supporting leg 19 can be adjusted, and the bottom of supporting leg 19 is provided with rubber blanket, is provided with the right side of the upper end of body 1
Rack 4, rack 4 can be placed specimen bag 5, and the upper end of specimen bag 5 is provided with feed tube 6, feed tube 6 connect to specimen plus
Hot thermostat 7, specimen heating constant-temperature equipment 7 connects to peristaltic pump 10, and peristaltic pump 10 connects ion-exchange chromatography by pipeline
Post 11, ion exchange column 11 is located at the upper left side of body 1, and the bottom of ion exchange column 11 is provided with colorimetric measuring device
12, colorimetric measuring device 12 is located at the left side of body 1 bottom；The top of described colorimetric measuring device 12 is connected with discharging tube, row
Liquid pipe connects to supercharger 3, and the lower section of supercharger 3 is provided with waste liquid bottle 2, the discharge opeing between colorimetric measuring device 12 and supercharger 3
Pipe is provided with filter 13, additionally, being additionally provided with pressure transducer 15 on discharge opeing official, the transducing signal of pressure transducer 15 is connected to aobvious
Show device 14, display 14 is located at the outside of body 1, pressure transducer 15 and display 14 are prior art, its annexation
Also there are a lot of applications in real life, admittedly will not be described here；The inside of described body 1 is additionally provided with reserving liquid tank 16, liquid storage
The inside of case 16 is provided with electric heater unit, and electric heater unit can heat to the liquid in reserving liquid tank 16 so that quilt
The liquid of heating can provide heat energy for specimen heating constant-temperature equipment 7, and the upper end of reserving liquid tank 16 is connected with liquid back pipe 8, reserving liquid tank
16 right-hand member is connected with Miniature liquid pump 17, just the liquid in reserving liquid tank 16 can be pumped into specimen heating by Miniature liquid pump 17
In thermostat 7, Miniature liquid pump 17 is connected with the second feed tube 18；The outside of described specimen heating constant-temperature equipment 7 is provided with circle
Cylindrical shell, the two ends of specimen heating constant-temperature equipment 7 are provided with end cap 23, and the middle part of end cap 23 is provided with circular groove, and specimen heats
It is provided with a circular siphunculus 21 inside the cylindrical housings of thermostat 7, in circular siphunculus 21, be provided with temperature sensor 9, circular
It is formed with the cavity 22 of ring-type, the two ends of circular siphunculus 21 are stuck in end cap 23 between siphunculus 21 and specimen heating constant-temperature equipment 7
In circular groove, in the cavity 22 of ring-type, it is provided with helical form heating tube 20, one end of helical form heating tube 20 connects feed tube 6,
Specimen is heated in helical form heating tube 20, and the left upper portion of the cavity 22 of ring-type is provided with liquid outlet, and liquid outlet is connected with
Liquid back pipe 8, the lower right side of the cavity 22 of ring-type is provided with inlet, and inlet is connected with the second feed tube 18；Using process
In, heated liquid in the cavity 22 that the second feed tube 18 enters into ring-type, then in cavity 22 and the helical form of ring-type
Heating tube 20 carries out heat exchange, thus the specimen in heating coil shape heating tube 20, hydrothermal solution enters into reserving liquid tank 16 from liquid back pipe 8
Interior, thus forming circulation, helical form heating tube 20 can be cooled uniformly in the cavity 22 of ring-type.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment party
Formula, in the ken that one skilled in the relevant art possesses, can also be on the premise of without departing from this patent objective
Make a variety of changes.
Claims (5)
1. a kind of glycolated hemoglobin analysis, including body (1), specimen heating constant-temperature equipment (7), peristaltic pump (10), ion
Displacement chromatography post (11), supercharger (3), colorimetric measuring device (12) and reserving liquid tank (16) are it is characterised in that described body (1)
Bottom be laid with multiple supporting legs (19), be provided with rack (4) on the right side of the upper end of body (1), rack can be placed on (4)
Specimen bag (5), the upper end of specimen bag (5) is provided with feed tube (6), and feed tube (6) connects to specimen heating constant-temperature equipment (7), marks
This heating constant-temperature equipment (7) connects to peristaltic pump (10), and peristaltic pump (10) connects ion exchange column (11) by pipeline, from
Sub- displacement chromatography post (11) is located at the upper left side of body (1), and the bottom of ion exchange column (11) is provided with colorimetric measuring device
(12), colorimetric measuring device (12) is located at the left side of body (1) bottom；The top of described colorimetric measuring device (12) is connected with row
Liquid pipe, discharging tube connects to supercharger (3), and the lower section of supercharger (3) is provided with waste liquid bottle (2), colorimetric measuring device (12) and increasing
Discharging tube between depressor (3) is provided with filter (13), additionally, being additionally provided with pressure transducer (15), pressure sensing on discharge opeing official
The transducing signal of device (15) is connected to display (14), and display (14) is located at the outside of body (1)；Described body (1) interior
Portion is additionally provided with reserving liquid tank (16), and the inside of reserving liquid tank (16) is provided with electric heater unit, and the upper end of reserving liquid tank (16) is connected with back liquid
Pipe (8), the right-hand member of reserving liquid tank (16) is connected with Miniature liquid pump (17), Miniature liquid pump (17) is connected with the second feed tube (18)；
The two ends of described specimen heating constant-temperature equipment (7) are provided with end cap (23), and the middle part of end cap (23) is provided with circular groove, and specimen heats
It is provided with a circular siphunculus (21) inside the cylindrical housings of thermostat (7), in circular siphunculus (21), be provided with temperature sensor
(9), it is formed with the cavity (22) of ring-type, the cavity (22) of ring-type between circular siphunculus (21) and specimen heating constant-temperature equipment (7)
Inside it is provided with helical form heating tube (20), one end of helical form heating tube (20) connects feed tube (6), a left side for the cavity (22) of ring-type
Upper lateral part is provided with liquid outlet, and liquid outlet is connected with liquid back pipe (8), and the lower right side of the cavity (22) of ring-type is provided with inlet.
2. a kind of glycolated hemoglobin analysis according to claim 1 are it is characterised in that the bottom of described supporting leg (19)
It is provided with rubber blanket.
3. a kind of glycolated hemoglobin analysis according to claim 1 are it is characterised in that the cavity (22) of described ring-type
Inlet on be connected with the second feed tube (18).
4. a kind of glycolated hemoglobin analysis according to claim 1 are it is characterised in that described specimen heated constant temperature fills
The outside putting (7) is provided with cylindrical housings.
5. a kind of glycolated hemoglobin analysis according to claim 1 are it is characterised in that described circle siphunculus (21)
Two ends are stuck in the circular groove of end cap (23).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611189085.8A CN106404982A (en) | 2016-12-21 | 2016-12-21 | Glycosylated hemoglobin analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611189085.8A CN106404982A (en) | 2016-12-21 | 2016-12-21 | Glycosylated hemoglobin analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106404982A true CN106404982A (en) | 2017-02-15 |
Family
ID=58087939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611189085.8A Pending CN106404982A (en) | 2016-12-21 | 2016-12-21 | Glycosylated hemoglobin analyzer |
Country Status (1)
| Country | Link |
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| CN (1) | CN106404982A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107192588A (en) * | 2017-03-24 | 2017-09-22 | 江苏奥迪康医学科技股份有限公司 | Glycolated hemoglobin analysis pressurizing filter system and method |
| CN113049796A (en) * | 2021-03-17 | 2021-06-29 | 王奔 | POCT glycated hemoglobin analyzer |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4416450A1 (en) * | 1994-05-10 | 1995-11-23 | Mptec Ges Fuer Mobile Probenen | Heating system for samples for analysis |
| JP2001194294A (en) * | 2000-01-12 | 2001-07-19 | Shimadzu Corp | Spectrophotometer |
| JP2006226780A (en) * | 2005-02-16 | 2006-08-31 | Fuji Photo Film Co Ltd | Measuring device using total reflection attenuation, and its measuring method |
| CN103245791A (en) * | 2013-05-02 | 2013-08-14 | 深圳市凯特生物医疗电子科技有限公司 | Integral low-pressure ion exchange glycosylated hemoglobin analyzer |
| CN203965971U (en) * | 2014-06-24 | 2014-11-26 | 蓝星有机硅（上海）有限公司 | Sample temperature regulating device |
| CN205808164U (en) * | 2016-06-28 | 2016-12-14 | 浙江泰康药业集团有限公司 | A kind of spiral tube heat exchanger |
-
2016
- 2016-12-21 CN CN201611189085.8A patent/CN106404982A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4416450A1 (en) * | 1994-05-10 | 1995-11-23 | Mptec Ges Fuer Mobile Probenen | Heating system for samples for analysis |
| JP2001194294A (en) * | 2000-01-12 | 2001-07-19 | Shimadzu Corp | Spectrophotometer |
| JP2006226780A (en) * | 2005-02-16 | 2006-08-31 | Fuji Photo Film Co Ltd | Measuring device using total reflection attenuation, and its measuring method |
| CN103245791A (en) * | 2013-05-02 | 2013-08-14 | 深圳市凯特生物医疗电子科技有限公司 | Integral low-pressure ion exchange glycosylated hemoglobin analyzer |
| CN203965971U (en) * | 2014-06-24 | 2014-11-26 | 蓝星有机硅（上海）有限公司 | Sample temperature regulating device |
| CN205808164U (en) * | 2016-06-28 | 2016-12-14 | 浙江泰康药业集团有限公司 | A kind of spiral tube heat exchanger |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107192588A (en) * | 2017-03-24 | 2017-09-22 | 江苏奥迪康医学科技股份有限公司 | Glycolated hemoglobin analysis pressurizing filter system and method |
| CN113049796A (en) * | 2021-03-17 | 2021-06-29 | 王奔 | POCT glycated hemoglobin analyzer |
| CN113640255A (en) * | 2021-03-17 | 2021-11-12 | 王奔 | Accurate instant detection POCT glycated hemoglobin analyzer |
| CN113640255B (en) * | 2021-03-17 | 2022-07-22 | 南京鸿瑞杰生物医疗科技有限公司 | Accurate instant detection POCT glycated hemoglobin analyzer |
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Application publication date: 20170215 |
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| RJ01 | Rejection of invention patent application after publication |