CN106389607A - Preparation method of blood circulation promoting and stasis removing traditional Chinese medicine formula for back pain - Google Patents
Preparation method of blood circulation promoting and stasis removing traditional Chinese medicine formula for back pain Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
Abstract
The invention discloses a preparation method of a blood circulation promoting and stasis removing traditional Chinese medicine formula for back pain. The method comprises specific steps as follows: (1) traditional Chinese medicinal materials are weighed and prepared in parts by weight; (2) the prepared raw materials are disinfected together; (3) the disinfected traditional Chinese medicinal materials are subjected to high-temperature and high-pressure extraction, and an extraction liquid is prepared; (4) the prepared extraction liquid is eluted with an ethanol solution, and obtained ethanol eluents are mixed; (5) the mixed ethanol eluent is concentrated, a concentrated liquid is dried, and dry extract powder is obtained; (6) the dry extract powder is freeze-dried, packaged and placed in a dry place for storage. The traditional Chinese medicine composition has no adverse effect during usage, has an obvious treatment effect on back pain, can be used by patients suffering from slight and severe back pain and is wide in application range, the preparation process of the traditional Chinese medicine composition is simple and standard, the medicine extraction efficiency is high, the property of the medicine can be well kept, and the prepared medicine is convenient to carry.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling.
Background technology
Lumbago, Chinese medical disease name.Refer to because of diseases caused by exogenous pathogenic factor, internal injury or frustrate sudden strain of a muscle and lead to waist QI-blood circulation not smooth, or lose foster in moistening,
Spinal column or the other tract pain of ridge is caused to be a kind of disease of cardinal symptom.Often with kidney asthenia as the principal aspect, being invaded by exogenous pathogen, tumbling down are frustrated for its morbidity
Dodge for mark.During treatment, excess syndrome focuses on eliminating evil and promotes blood circulation active, and deficiency syndrome focus on righting, and invigorating the liver and kidney, strong waist and knee, spleen invigorating gas are conventional controlling
Method.Lumbago with the passing of time, simulataneous insufficiency and excessive, treatment should grasp specimen deficiency and excess, from the method for eliminating evil and reinforcing.
Treatment pain in the lumbar region uses the Chinese crude drug effect of Chinese tradition more preferably, but the chemical analysis of Chinese medicine are sufficiently complex, existing contains
There are multiple active ingredients, have invalid element again, also comprise toxic substance, how to select raw material of Chinese medicine to be combined formula and become controlling
Treating the important step of pain in the lumbar region, and the compound method for Chinese medicine composition, using more preferable technology, can improve
The drug effect of medicine.
Content of the invention
It is an object of the invention to provide one kind can significantly slow pain in the lumbar region symptom, preparation flow specification, extract drugs efficiency
A kind of preparation method of the pain in the lumbar region Chinese medicine formula of high blood circulation promoting and blood stasis dispelling.
The present invention is achieved through the following technical solutions：A kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling, including
Following steps：
（1）By weight, weigh Radix Gentianae Macrophyllae 4-16 part, Radix Astragali 3-21 part, Rhizoma Atractylodis Macrocephalae 3-22 part, Radix Angelicae Sinensis 2-18 part, Pericarpium Citri Reticulatae 5-18 part,
Radix Bupleuri 4-16 part, Rhizoma Cimicifugae 3-23 part, Semen Persicae 5-25 part, Oletum Trogopterori 3-15 part, eupolyphage sece steleophaga 5-15 part, configure traditional Chinese medicinal material raw materials；
（2）The traditional Chinese medicinal material raw materials unification that configuration is finished carries out disinfection；
（3）The traditional Chinese medicinal material raw materials that sterilization is completed carry out High Temperature High Pressure extraction, prepared extract；
（4）Ethanol solution using 95% is to step（3）In be obtained extract carry out eluting, and will obtain alcohol eluen mixing；
（5）Concentrate mixed ethanol elution further, obtain the concentrated solution that proportion is 0.6 ~ 0.8, concentrated solution is sprayed
Mist is dried to obtain extract dry powder；
（6）Lyophilization, encapsulation, it is placed in the place of drying and preserves, obtain final product.
A kind of crude drug pharmacology of the preparation method of pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling of the present invention：
Radix Gentianae Macrophyllae：Mild-natured, bitter in the mouth, pungent.Return stomach, Liver Channel, gallbladder meridian, wind-damp dispelling, reducing the asthenic fever, relaxing muscles and tendons relieve the pain, be that treatment rheumatism is closed
One of principal agents of disease such as arthralgia.
The Radix Astragali：Sweet in the mouth, slightly warm in nature, return lung, spleen, liver and kidney channel, it has enhancing human body immunity function, liver protection, diuresis, anti-ageing
Always, anti-stress, blood pressure lowering and wide antibacterial action.
The Rhizoma Atractylodis Macrocephalae：Bitter in the mouth, sweet, warm in nature, returns spleen, stomach, the Rhizoma Atractylodis Macrocephalae has an invigorating the spleen and benefiting QI, eliminate dampness and have diuretic effect, hidroschesis, antiabortive work(
Effect.
Radix Angelicae Sinensis：Sweet in the mouth, pungent, warm in nature, Return liver, the heart, spleen channel, have a benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, anticancer, anti-
The effect of always prevent old, immune.
Pericarpium Citri Reticulatae：Bitter in the mouth, pungent, warm in nature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.
Radix Bupleuri：Acrid in the mouth, hardship, cold nature, Return liver, gallbladder, lung meridian, there is reconciling superficies and interior, the effect of soothing the liver yang invigorating.
Rhizoma Cimicifugae：Cold nature, acrid in the mouth, micro-sweet.Return lung warp, spleen channel, stomach, large intestine channel, have deliver rash, heat-clearing and toxic substances removing,
Rise the effect lifting yang-energy.
Semen Persicae：Mild-natured, bitter in the mouth, sweet.Thoughts of returning home warp, Liver Channel, large intestine channel, have functions that activating blood circulation and dissipating phlegm, loosening bowel to relieve constipation.
For optimizing the effect of drugs of medicine, further, 11 parts of described Radix Gentianae Macrophyllae, 15 parts of the Radix Astragali, 18 parts of the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis 14
Part, 11 parts of Pericarpium Citri Reticulatae, 15 parts of Radix Bupleuri, 20 parts of Rhizoma Cimicifugae, 10 parts of Semen Persicae.
Further, described step（2）Middle disinfection way adopts high-temperature steam sterilization.
Further, described step（4）The concentration of middle ethanol solution is 95%.
Further, described step（5）Using the concentrate bottle of ceramic material in middle concentration process.
Further, described step（5）Middle drying mode is using spray drying.
The Chinese medicine composition of the present invention does not have untoward reaction in use, and the treatment to pain in the lumbar region has obvious effect
Really, slight and severe pain in the lumbar region patient can use, applied widely, the preparation flow simple specification of Chinese medicine composition, medicine
Extraction efficiency is high, can keep the property of medicine of medicine well, the medicine after preparation is easy to carry.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, but embodiments of the present invention not limited to this,
Without departing from the idea case in the present invention described above, according to ordinary skill knowledge and customary means, make various replacing
Change and change, all should be included within the scope of the invention.
Embodiment 1：
A kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling described in the present embodiment, comprises the following steps：
（1）By weight, weigh Radix Gentianae Macrophyllae 4-16 part, Radix Astragali 3-21 part, Rhizoma Atractylodis Macrocephalae 3-22 part, Radix Angelicae Sinensis 2-18 part, Pericarpium Citri Reticulatae 5-18 part,
Radix Bupleuri 4-16 part, Rhizoma Cimicifugae 3-23 part, Semen Persicae 5-25 part, Oletum Trogopterori 3-15 part, eupolyphage sece steleophaga 5-15 part, configure traditional Chinese medicinal material raw materials；
（2）The traditional Chinese medicinal material raw materials unification that configuration is finished carries out disinfection；
（3）The traditional Chinese medicinal material raw materials that sterilization is completed carry out High Temperature High Pressure extraction, prepared extract；
（4）Ethanol solution using 95% is to step（3）In be obtained extract carry out eluting, and will obtain alcohol eluen mixing；
（5）Concentrate mixed ethanol elution further, obtain the concentrated solution that proportion is 0.6 ~ 0.8, concentrated solution is sprayed
Mist is dried to obtain extract dry powder；
（6）Lyophilization, encapsulation, it is placed in the place of drying and preserves, obtain final product.
Wherein, described step（2）Middle disinfection way adopts high-temperature steam sterilization；Described step（4）Middle ethanol solution dense
Spend for 95%；Described step（5）Using the concentrate bottle of ceramic material in middle concentration process；Described step（5）Middle drying mode adopts
It is spray-dried.
Embodiment 2：
The pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling described in the present embodiment, by weight, including：11 parts of Radix Gentianae Macrophyllae, 15 parts of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae
18 parts, 14 parts of Radix Angelicae Sinensis, 11 parts of Pericarpium Citri Reticulatae, 15 parts of Radix Bupleuri, 20 parts of Rhizoma Cimicifugae, 10 parts of Semen Persicae.
Embodiment 3：
The present embodiment, on the basis of above-described embodiment, further, also includes Oletum Trogopterori 3-15 part, eupolyphage sece steleophaga 5-15 part.I.e.
The pain in the lumbar region Chinese medicine formula of this blood circulation promoting and blood stasis dispelling, by weight, including：11 parts of oxtail Radix Gentianae Macrophyllae, 15 parts of the Radix Astragali, 18 parts of the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis
14 parts, 11 parts of Pericarpium Citri Reticulatae, 15 parts of Radix Bupleuri, 20 parts of Rhizoma Cimicifugae, 10 parts of Semen Persicae, 12 parts of Oletum Trogopterori, 10 parts of eupolyphage sece steleophaga.
The other parts of the present embodiment are same as the previously described embodiments, repeat no more.
Embodiment 4：
The present embodiment provides the pain in the lumbar region Chinese medicine formula toxicology test of this blood circulation promoting and blood stasis dispelling, specific as follows：
Acute toxicity test：
Experimental observation, because measuring LD50, therefore has carried out the mensure of maximum dosage-feeding.Chinese medicine composition prepared by embodiment 1
Thing is dissolved in sterile saline, is configured to solution gavage mice, and result shows, raw with medicine maximum administration concentration 9.65
Medicine/ml, maximum administered volume 50ml/kg was administered twice to mouse stomach in 24 hours, and mice maximum dosage-feeding is 763.25g
Crude drug/kg, untoward reaction and death in animal, anatomic observation each internal organs no abnormality seen.
Long term toxicity test
SD rat 80 is applied in this test, and Chinese medicine composition prepared by embodiment 1 is dissolved in sterile saline, is configured to
Solution gavage, if matched group and 24g, 35g, 49g crude drug/kg dosage group, continuous gavage is administered 12 weeks, observes the Chinese medicine of the present invention
The impact to animal indices for the compositionss.Result of the test shows, successive administration 12 weeks, and the Chinese medicine composition of the present invention is to rat
Body weight, food ration, peripheral hemogram, clotting time, electrocardiogram, organ index etc. all have no significant effect；Blood biochemical ten binomial
Index determining result, 12 weeks low dose group BiLi values of administration are higher than matched group（P<0.05)；Low dose group, middle dose group TP value are high
In matched group（P<0.05), but all within normal physiologic range, other indexs compare no significant difference with matched group.Convalescent period
Each administration group indices measured value compares equal no significant difference with matched group.Each group each internal organs gross examination of skeletal muscle no abnormality seen.
The using method of medicine of the present invention：Directly take orally.
Pain in the lumbar region diagnostic criteria：
Slight pain in the lumbar region：It is unable to strenuous exercise at ordinary times, having heavy burden sense through long-time work back lumbar part, with paroxysmal pain, rest
Have after a period of time and taken a turn for the better.
Moderate pain in the lumbar region：Stand up after sitting to have pain, can take a favorable turn after movable waist, but waist can muscle after suffering from cold
Spasm, has fixing obvious pressure pain point.
Severe pain in the lumbar region：Sitting or lying on bed for a long time back lumbar part muscle rigidity, stand up to have pain it is impossible to normal activity is it is impossible to curved
Waist and turning round, night cannot fall asleep, and lower back has neuropathic pain, waist muscle atrophy.
Recovery from illness standard：Waist no longer has pain, can perform physical exercises, overcast and rainy will not with pain in the lumbar region situation.
Effectively standard：Flank pain sense substantially mitigates, and can carry out appropriate sports, can freely rise after sitting
Body.
Null criterion：Flank pain sense still exists, and sombre sky waist also can pain, sitting back lumbar part muscle is stiff
Firmly, the effect of pain no mitigation.
It is directed to the clinical statisticses data of various pain in the lumbar region patients using medicine of the present invention：
Through the Clinical practice of 200 patients, wherein male patient 127, female patient 73, medication age object 20 ~ 60 years old.Wherein
Minimum 21 years old, maximum 59 years old, 38 years old mean age；Slight pain in the lumbar region 42, moderate pain in the lumbar region 72, severe pain in the lumbar region 36.
Model case：
1st, Lee, man, 51 years old, severe pain in the lumbar region patient, due to a long-term northeastward band job at an early age, lead to back catching cold, and
And never pay close attention to waist health, and carry out motion drastically in the state of suffering from cold, led to be in a bad way now, lower back
The change of the blood circulation aspect such as vasoconstriction, ischemia, congestion, edema and make patient produce lumbago, and can be because of Changes in weather
And lumbago occurring or lumbago increases, lumbago symptom can be accurate as weather forecast, can the state of an illness add on rainy day and cold snap
Weight, is usually unable to leave the bed, action is inconvenient.Prescription using the embodiment of the present invention 3 takes 8 courses for the treatment of orally, and pain in the lumbar region symptom is notable
Mitigate, stable can sleep, can independently get up in the evening, daily routines also very freely, have reached the degree taken care of oneself.
2nd, Sun, man, 34 years old, slight pain in the lumbar region patient, situation pain in the lumbar region is led to due to the long-term sitting of working principle,
The portion that may feel that after getting up in the morning powerless situation of flaccid muscles.Simultaneously although there is no rheumatism or wound, but often feel
The myalgia uncomfortable to back, chest has constriction and delocalization.Prescription using the embodiment of the present invention 3 takes 4 courses for the treatment of orally,
Enrich strong in back lumbar part of getting up, paroxysmal pain and constriction no longer in muscle of back.
3rd, week certain, man, 52 years old, severe pain in the lumbar region patient, with advancing age, the false vertebra that causes because of degeneration
Post slips, lumbar spinal stenosises, oppresses spinal cord and nerve root, leads to lumbago and lower limb rediating pain, simultaneously also with persistence lumbago.
Take orally after 10 courses for the treatment of using the prescription of the embodiment of the present invention 3, the pain in activity for the waist has obvious mitigation, and holds
Continuous pain disappears, can be voluntarily movable, and waist no longer has heavy burden sense.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not
Multiple changes, modification, replacement and modification can be carried out to these embodiments under the principle of the disengaging present invention and objective, the present invention's
Scope is limited by claim and its equivalent.
Claims (5)
1. a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling is it is characterised in that comprise the following steps：
（1）By weight, weigh Radix Gentianae Macrophyllae 4-16 part, Radix Astragali 3-21 part, Rhizoma Atractylodis Macrocephalae 3-22 part, Radix Angelicae Sinensis 2-18 part, Pericarpium Citri Reticulatae 5-18 part,
Radix Bupleuri 4-16 part, Rhizoma Cimicifugae 3-23 part, Semen Persicae 5-25 part, Oletum Trogopterori 3-15 part, eupolyphage sece steleophaga 5-15 part, configure traditional Chinese medicinal material raw materials；
（2）The traditional Chinese medicinal material raw materials unification that configuration is finished carries out disinfection；
（3）The traditional Chinese medicinal material raw materials that sterilization is completed carry out High Temperature High Pressure extraction, prepared extract；
（4）Ethanol solution using 95% is to step（3）In be obtained extract carry out eluting, and will obtain alcohol eluen mixing；
（5）Concentrate mixed ethanol elution further, obtain the concentrated solution that proportion is 0.6 ~ 0.8, concentrated solution is sprayed
Mist is dried to obtain extract dry powder；
（6）Lyophilization, encapsulation, it is placed in the place of drying and preserves, obtain final product.
2. a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling according to claim 1 is it is characterised in that described
Step（2）Middle disinfection way adopts high-temperature steam sterilization.
3. a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling according to claim 1 is it is characterised in that described
Step（4）The concentration of middle ethanol solution is 95%.
4. a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling according to claim 1 is it is characterised in that described
Step（5）Using the concentrate bottle of ceramic material in middle concentration process.
5. a kind of preparation method of the pain in the lumbar region Chinese medicine formula of blood circulation promoting and blood stasis dispelling according to claim 1 is it is characterised in that described
Step（5）Middle drying mode is using spray drying.
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| CN201610974813.XA CN106389607A (en) | 2016-11-07 | 2016-11-07 | Preparation method of blood circulation promoting and stasis removing traditional Chinese medicine formula for back pain |
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| CN201610974813.XA CN106389607A (en) | 2016-11-07 | 2016-11-07 | Preparation method of blood circulation promoting and stasis removing traditional Chinese medicine formula for back pain |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101259201A (en) * | 2008-04-21 | 2008-09-10 | 全光彪 | Antirheumatic pain relieving medicaments |
| CN104147264A (en) * | 2014-07-14 | 2014-11-19 | 贾富平 | Pharmaceutical formula for treating lumbago and preparation method thereof |
-
2016
- 2016-11-07 CN CN201610974813.XA patent/CN106389607A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101259201A (en) * | 2008-04-21 | 2008-09-10 | 全光彪 | Antirheumatic pain relieving medicaments |
| CN104147264A (en) * | 2014-07-14 | 2014-11-19 | 贾富平 | Pharmaceutical formula for treating lumbago and preparation method thereof |
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Application publication date: 20170215 |