CN106389573A - Rheumatism liquid for curing gonitis - Google Patents
Rheumatism liquid for curing gonitis Download PDFInfo
- Publication number
- CN106389573A CN106389573A CN201611008082.XA CN201611008082A CN106389573A CN 106389573 A CN106389573 A CN 106389573A CN 201611008082 A CN201611008082 A CN 201611008082A CN 106389573 A CN106389573 A CN 106389573A
- Authority
- CN
- China
- Prior art keywords
- radix
- fengshi
- rhizoma
- colla
- radix angelicae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010003246 arthritis Diseases 0.000 title claims abstract description 15
- 239000007788 liquid Substances 0.000 title abstract description 26
- 241001421185 Anomis Species 0.000 title abstract 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 13
- 241001550206 Colla Species 0.000 claims description 23
- 241000209020 Cornus Species 0.000 claims description 12
- 241000628997 Flos Species 0.000 claims description 12
- 235000002322 Monascus purpureus Nutrition 0.000 claims description 12
- 244000113306 Monascus purpureus Species 0.000 claims description 12
- 229940057059 monascus purpureus Drugs 0.000 claims description 12
- 230000003071 parasitic effect Effects 0.000 claims description 11
- 239000003814 drug Substances 0.000 abstract description 22
- 239000008280 blood Substances 0.000 abstract description 21
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 21
- 210000004185 liver Anatomy 0.000 abstract description 20
- 210000004369 blood Anatomy 0.000 abstract description 19
- 230000000694 effects Effects 0.000 abstract description 19
- 210000003734 kidney Anatomy 0.000 abstract description 19
- 208000006820 Arthralgia Diseases 0.000 abstract description 18
- 201000010099 disease Diseases 0.000 abstract description 12
- 230000007812 deficiency Effects 0.000 abstract description 10
- 208000025747 Rheumatic disease Diseases 0.000 abstract description 8
- 208000034783 hypoesthesia Diseases 0.000 abstract description 8
- 230000000552 rheumatic effect Effects 0.000 abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 230000024241 parasitism Effects 0.000 abstract description 2
- 239000003292 glue Substances 0.000 abstract 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 244000189799 Asimina triloba Species 0.000 abstract 1
- 235000006264 Asimina triloba Nutrition 0.000 abstract 1
- 235000009467 Carica papaya Nutrition 0.000 abstract 1
- 241000501743 Gentiana macrophylla Species 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 210000000629 knee joint Anatomy 0.000 description 20
- 201000008482 osteoarthritis Diseases 0.000 description 18
- 208000003947 Knee Osteoarthritis Diseases 0.000 description 11
- 230000006378 damage Effects 0.000 description 10
- 230000008961 swelling Effects 0.000 description 9
- 206010061218 Inflammation Diseases 0.000 description 8
- 230000000202 analgesic effect Effects 0.000 description 8
- 210000000845 cartilage Anatomy 0.000 description 8
- 230000004054 inflammatory process Effects 0.000 description 8
- 102100027995 Collagenase 3 Human genes 0.000 description 7
- 108050005238 Collagenase 3 Proteins 0.000 description 7
- 208000004044 Hypesthesia Diseases 0.000 description 7
- 102000000380 Matrix Metalloproteinase 1 Human genes 0.000 description 7
- 108010016113 Matrix Metalloproteinase 1 Proteins 0.000 description 7
- 230000003110 anti-inflammatory effect Effects 0.000 description 7
- 210000003414 extremity Anatomy 0.000 description 7
- 231100000862 numbness Toxicity 0.000 description 7
- 210000001258 synovial membrane Anatomy 0.000 description 7
- 210000002435 tendon Anatomy 0.000 description 7
- 230000001256 tonic effect Effects 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 5
- 238000003304 gavage Methods 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 206010025482 malaise Diseases 0.000 description 3
- 208000037920 primary disease Diseases 0.000 description 3
- FEJKLNWAOXSSNR-UHFFFAOYSA-N benorilate Chemical compound C1=CC(NC(=O)C)=CC=C1OC(=O)C1=CC=CC=C1OC(C)=O FEJKLNWAOXSSNR-UHFFFAOYSA-N 0.000 description 2
- 229960004277 benorilate Drugs 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- ZKRFOXLVOKTUTA-KQYNXXCUSA-N 9-(5-phosphoribofuranosyl)-6-mercaptopurine Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NC=NC2=S)=C2N=C1 ZKRFOXLVOKTUTA-KQYNXXCUSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 101000669513 Homo sapiens Metalloproteinase inhibitor 1 Proteins 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241000406668 Loxodonta cyclotis Species 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 102100039364 Metalloproteinase inhibitor 1 Human genes 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 241000736919 Pelodiscus sinensis Species 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002917 arthritic effect Effects 0.000 description 1
- 210000001188 articular cartilage Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003042 chondroprotective agent Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000005786 degenerative changes Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000001969 hypertrophic effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000008407 joint function Effects 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000005065 subchondral bone plate Anatomy 0.000 description 1
- 201000004595 synovitis Diseases 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a rheumatism liquid for curing gonitis, wherein the rheumatism liquid is characterized by comprising 5-15g of radix angelicae pubescentis, 5-10g of parasitism, 5-10g of notopterygium roots, 10-15g of radix saposhnikoviae, 5-10g of largeleaf gentian roots, 5-10g of pawpaws, 8-15g of deer-horn glue, 1-9g of turtle shell glue, 1-9g of radix achyranthis bidentatae, 10-15g of ligusticum wallichii, 5-15g of angelica sinensis and 10-15g of radix paeoniae alba. The rheumatism liquid is taken one time each day, and is decocted with water to prepare a solution of 600-800ml according to the convention, and the solution is taken twice respectively on the morning and the evening each day. The traditional Chinese medicine has the effects of tonifying liver and kidney, dispelling wind, eliminating dampness, nourishing blood and dredging collaterals, has achieved an excellent curative effect on clinically curing the arthralgia disease, and has an excellent curative effect on joint pain and numbness of limbs, caused by deficiency of blood of liver and kidney and wind cold damp impediment, as well as rheumatic and rheumatoid diseases.
Description
Technical field
The present invention relates to a kind of FENGSHI YE treating gonarthritis.
Background technology
Osteoarthritis (OA) are a kind of common chronic degenerative joint disease, with articular cartilage degenerative change as core,
With Subchondral bone sclerosis, the Hypertrophic change of osseous tissue and joint synovitis disease etc., by wound, strain, obesity, wait for a long time in year multiple
Factor should be sent out, and clinic often shows as arthralgia, swelling, stiff, limitation of activity, joint deformity, different degrees of local inflammation,
Occasionally joint fluid is had to ooze out.Primary disease is multiple after the middle age, and with advancing age, its sickness rate significantly increases.According to statistics, 50 years old
In above people, the sickness rate of osteoarthritis reaches 50%, in the people of over-65s, and the sickness rate of osteoarthritis reaches
80%.Knee joint heavy burden is many, quantity of motion is big, is to be easiest to occur arthritic osteoarthrosis, knee osteoarthritis (KOA) are person in middle and old age
One of modal disease in crowd, badly influences normal walking and the activity of middle-aged and elderly people, endangers their healthy,
And bring white elephant to family and society, WH0 is classified as knee osteoarthritis, cancer, cardiovascular disease jointly within 1999
Three big killers of harm human health.Therefore knee osteoarthritis are increasingly subject to people's attention, its prevention and treatment become each
One big problem of the common concern of state's medical circle.The concrete Therapeutic Method of knee osteoarthritis should select according to the degree of patient disease
Select, the early stage of knee osteoarthritis should adopt noninvasive Therapeutic Method as far as possible, and the knee osteoarthritis late period that internal medicine is failed to respond to any medical treatment can
Using operative treatment.In early stage Drug therapy, conventional Western medicine is divided into and improves symptom medicine and symptom management medicine two class.Improve disease
The medicine of shape includes analgesic, nonsteroidal antiinflammatory drug, glucocorticoid etc., and these medicines can mitigate the pain of patient, swelling, deadlock
The symptom such as hard, but more using rear untoward reaction, it is also easy to produce gastrointestinal complication, causes liver, renal damage, patient compliance is relatively
Difference；The medicine of symptom management has Chondroprotective agents, TIMP etc., and these medicines can reduce the destruction of cartilage,
Delay the development of knee osteoarthritis pathological process, but limit popularization because expensive.Clinical report shows, Chinese medicine is to knee joint
The prevention and treatment of osteoarthritis have accumulated much square medicine and experience for many years, with organic conception, dialectical treatmert as principle, from knee joint
Local joint medication and whole body integrally set out, and release the symptom of knee osteoarthritis, improve knee joint function, protection knee joint knot
Structure.Relatively for Western medicine, Chinese medicine is not only evident in efficacy to knee joint osseous arthritiies early stage patient, and safety preferably,
Inexpensive, suitable life-time service, this makes it clinically have certain treatment advantage.Therefrom medical angle analysis, knee osteoarthritis
Belong to " arthromyodynia ", " rheumatism involving the bone " category.Its cause of disease main with caused by liver and kidney deficiency, qi-blood disharmony, affection of exogenous wind-cold damp, traumatic injury etc. have
Close, ultimately result in local stagnation of QI and blood, run not smooth, obstruction of meridians and collaterals is obstructed.Theory of Chinese medical science thinks that the basic pathogenesis of primary disease are these
Empty mark is real, is the basic of pathological changes when caused by liver and kidney deficiency, insufficiency of vital energy and blood, and anemofrigid-damp arthralgia resistance meridians, stagnation of QI-blood are mark.Specimen is simultaneous
Gu, strengthening vital QI to eliminate pathogenic factors are the basic rule for the treatment of of knee osteoarthritis, so the treatment of primary disease it is critical only that the liver and the kidney tonifying, dehumidifying cold expelling, work
Blood dredging collateral.
Content of the invention
The present invention proposes a kind of FENGSHI YE treating gonarthritis.
A kind of FENGSHI YE treating gonarthritis, take Radix Angelicae Pubescentiss 5-15g, parasitic 5-10g, Rhizoma Et Radix Notopterygii 5-10g, Radix Saposhnikoviae 10-15g,
Radix Gentianae Macrophyllae 5-10g, Fructus Chaenomeliss 5-10g, Colla cornus cervi 8-15g, Colla carapax Trionyciss 1-9g, Radix Achyranthis Bidentatae 1-9g, Rhizoma Chuanxiong 10-15g, Radix Angelicae Sinensis 5-15g, the Radix Paeoniae Alba
10-15g, daily 1 dose, routinely decocting one-tenth about 600～800ml solution, point 2 sub-services sooner or later.
Preferably, Radix Angelicae Pubescentiss 10g, parasitic 8g, Rhizoma Et Radix Notopterygii 8g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 8g, Fructus Chaenomeliss 8g, Colla cornus cervi 8g, Colla carapax Trionyciss are taken
3g, Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 4g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 12g.
Preferably, Radix Angelicae Pubescentiss 5g, parasitic 5g, Rhizoma Et Radix Notopterygii 5g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 5g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Colla carapax Trionyciss are taken
3g, Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 10g.
Preferably, Radix Angelicae Pubescentiss 15g, parasitic 10g, Rhizoma Et Radix Notopterygii 10g, Radix Saposhnikoviae 15g, Radix Gentianae Macrophyllae 10g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Trionyx sinensis Wiegmann are taken
Nail gelatin 6g, Radix Achyranthis Bidentatae 5g, Rhizoma Chuanxiong 15g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g.
It is further preferred that also including Flos Carthami 10-15g, Rhizoma Atractylodis Macrocephalae 15-20g, Radix Glycyrrhizae 15-20g, Monas cuspurpureus Went 3-5g.
It is further preferred that also including Flos Carthami 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 15g, Monas cuspurpureus Went 3g.
It is further preferred that also including Flos Carthami 15g, Rhizoma Atractylodis Macrocephalae 20g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
It is further preferred that also including Flos Carthami 12g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
Chinese medicine of the present invention, has tonic liver.Kidney, the effects such as expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treatment numbness disease
Oneself obtains preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, rheumatoid
Property disease has good efficacy.
Specific embodiment
Embodiment 1
A kind of FENGSHI YE treating gonarthritis, takes Radix Angelicae Pubescentiss 5-15g, parasitic 5-10g, Rhizoma Et Radix Notopterygii 5-10g, Radix Saposhnikoviae 10-15g, Radix Gentianae Macrophyllae
5-10g, Fructus Chaenomeliss 5-10g, Colla cornus cervi 8-15g, Colla carapax Trionyciss 1-9g, Radix Achyranthis Bidentatae 1-9g, Rhizoma Chuanxiong 10-15g, Radix Angelicae Sinensis 5-15g, Radix Paeoniae Alba 10-
15g, daily 1 dose, routinely decocting one-tenth about 600～800ml solution, point 2 sub-services sooner or later.Preferably, Radix Angelicae Pubescentiss 10g, parasitism are taken
8g, Rhizoma Et Radix Notopterygii 8g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 8g, Fructus Chaenomeliss 8g, Colla cornus cervi 8g, Colla carapax Trionyciss 3g, Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 4g, Radix Angelicae Sinensis 5g, the Radix Paeoniae Alba
12g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.
Take KM mice 72, SPF level, male, 18 229, it is randomly divided into 6 groups by body weight, every group 12.If distilled water mould
Type group, 40% wine solution model group, positive (benorilate tablet) matched group, dosage is 0.59 (benorylate)/kg, is equivalent to clinical day
20 times of recommended dose, original liquid of the present invention divides high, medium and low dosage group, and dosage is respectively 0.709,0.359,0.179/
Kg, is equivalent to 20,10,5 times of clinical day recommended dose.Distilled water model group gavage gives distilled water, 40% wine solution model
Group gives 40% wine solution, and other each group gavages give corresponding medicine, and continuous gavage is administered 5 days, once a day, gavage volume
For 0.15ml/109.Find after observation that medicinal liquid sufficient pawl swelling degree of the present invention substantially reduces.
Embodiment 2
The present embodiment take Radix Angelicae Pubescentiss 5g, parasitic 5g, Rhizoma Et Radix Notopterygii 5g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 5g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Colla carapax Trionyciss 3g,
Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 10g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Embodiment 3
Preferably, Radix Angelicae Pubescentiss 15g, parasitic 10g, Rhizoma Et Radix Notopterygii 10g, Radix Saposhnikoviae 15g, Radix Gentianae Macrophyllae 10g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Colla carapax Trionyciss are taken
6g, Radix Achyranthis Bidentatae 5g, Rhizoma Chuanxiong 15g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Embodiment 4
It is further preferred that also including Flos Carthami 10-15g, Rhizoma Atractylodis Macrocephalae 15-20g, Radix Glycyrrhizae 15-20g, Monas cuspurpureus Went 3-5g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Embodiment 5
It is further preferred that also including Flos Carthami 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 15g, Monas cuspurpureus Went 3g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Embodiment 6
It is further preferred that also including Flos Carthami 15g, Rhizoma Atractylodis Macrocephalae 20g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Embodiment 7
It is further preferred that also including Flos Carthami 12g, Rhizoma Atractylodis Macrocephalae 15g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
Medicinal liquid of the present invention has antiinflammatory, analgesic activity, it is possible to decrease in knee joint endoprosthesis liquid, MMP-1, MMP-13's contains
Amount, thus mitigate the damage of knee joint endoprosthesis synovial membrane inflammation and cartilage.Medicinal liquid sufficient pawl swelling degree of the present invention is found after observation
Substantially reduce.Chinese medicine described in the present embodiment has the effects such as tonic liver, kidney, expelling wind and removing dampness, blood nourishing acupuncture-stimulating, clinically treats numbness
Disease is own to obtain preferable curative effect, the arthralgia that Liver and kidney blood deficiency, anemofrigid-damp arthralgia are caused, numb limbs and tense tendons, and rheumatic, class wind
Moist disease has good efficacy.
Claims (8)
1. a kind of FENGSHI YE treating gonarthritis it is characterised in that：Take Radix Angelicae Pubescentiss 5-15g, parasitic 5-10g, Rhizoma Et Radix Notopterygii 5-10g, prevent
Wind 10-15g, Radix Gentianae Macrophyllae 5-10g, Fructus Chaenomeliss 5-10g, Colla cornus cervi 8-15g, Colla carapax Trionyciss 1-9g, Radix Achyranthis Bidentatae 1-9g, Rhizoma Chuanxiong 10-15g, Radix Angelicae Sinensis
5-15g, Radix Paeoniae Alba 10-15g, daily 1 dose, routinely decocting one-tenth about 600～800ml solution, point 2 sub-services sooner or later.
2. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Take Radix Angelicae Pubescentiss 10g, parasitic 8g, Qiang
Live 8g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 8g, Fructus Chaenomeliss 8g, Colla cornus cervi 8g, Colla carapax Trionyciss 3g, Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 4g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 12g.
3. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that taking Radix Angelicae Pubescentiss 5g, parasitic 5g, Rhizoma Et Radix Notopterygii
5g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 5g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Colla carapax Trionyciss 3g, Radix Achyranthis Bidentatae 3g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 5g, Radix Paeoniae Alba 10g.
4. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Take Radix Angelicae Pubescentiss 15g, parasitic 10g, Qiang
Live 10g, Radix Saposhnikoviae 15g, Radix Gentianae Macrophyllae 10g, Fructus Chaenomeliss 10g, Colla cornus cervi 8g, Colla carapax Trionyciss 6g, Radix Achyranthis Bidentatae 5g, Rhizoma Chuanxiong 15g, Radix Angelicae Sinensis 15g, the Radix Paeoniae Alba
15g.
5. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Also include Flos Carthami 10-15g, white
Art 15-20g, Radix Glycyrrhizae 15-20g, Monas cuspurpureus Went 3-5g.
6. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Also include Flos Carthami 10g, the Rhizoma Atractylodis Macrocephalae
15g, Radix Glycyrrhizae 15g, Monas cuspurpureus Went 3g.
7. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Also include Flos Carthami 15g, the Rhizoma Atractylodis Macrocephalae
20g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
8. as claimed in claim 1 a kind of FENGSHI YE treating gonarthritis it is characterised in that：Also include Flos Carthami 12g, the Rhizoma Atractylodis Macrocephalae
15g, Radix Glycyrrhizae 20g, Monas cuspurpureus Went 5g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611008082.XA CN106389573A (en) | 2016-11-16 | 2016-11-16 | Rheumatism liquid for curing gonitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611008082.XA CN106389573A (en) | 2016-11-16 | 2016-11-16 | Rheumatism liquid for curing gonitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106389573A true CN106389573A (en) | 2017-02-15 |
Family
ID=59230500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611008082.XA Pending CN106389573A (en) | 2016-11-16 | 2016-11-16 | Rheumatism liquid for curing gonitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106389573A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108703993A (en) * | 2018-08-08 | 2018-10-26 | 福建中医药大学 | Flourish muscle picks up the preparation process of pain side |
-
2016
- 2016-11-16 CN CN201611008082.XA patent/CN106389573A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108703993A (en) * | 2018-08-08 | 2018-10-26 | 福建中医药大学 | Flourish muscle picks up the preparation process of pain side |
| CN108703993B (en) * | 2018-08-08 | 2021-08-13 | 福建中医药大学 | Preparation process of RongjinNiantong prescription |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100376229C (en) | A medicinal wine for treating rheumatic and rheumatoid disease | |
| CN103784887A (en) | Traditional Chinese medicinal composition for treating kidney deficiency lumbago | |
| CN101181568B (en) | Traditional chinese medicine preparation for curing osteoproliferation as well as arthrosis ache | |
| CN103505659A (en) | Chinese proprietary medicine for treating rheumatoid arthritis | |
| CN104161868A (en) | Drug for treating rheumatoid arthritis | |
| CN103330806A (en) | Drug for treatment of rheumatoid arthritis | |
| CN102872301B (en) | Anti-rheumatism medicinal liquor and using method thereof | |
| CN108295128B (en) | Traditional Chinese medicine compound preparation for treating rheumatoid arthritis and preparation method thereof | |
| CN103316296B (en) | Traditional Chinese medicine composition for treating hyperostosis | |
| CN106389573A (en) | Rheumatism liquid for curing gonitis | |
| CN102406870B (en) | Medicament for treating rheumatic arthralgia | |
| CN103830672A (en) | Traditional Chinese medicine for treating scapulohumeral periarthritis | |
| CN103127458A (en) | Drug for treating osteoarticular myalgia | |
| CN103877239B (en) | A kind of Chinese medicine composition and its preparation method and application being used for the treatment of rheumatism, rheumatoid arthritis | |
| CN102366602A (en) | Traditional Chinese medicine formula used for treating rheumatism | |
| CN105770294A (en) | Traditional Chinese medicine composition for treating hysteromyoma | |
| CN103316133B (en) | Medicine for treating lame impediment | |
| CN103349767B (en) | Inula nervosa Wall oil capsule preparation and preparation method thereof | |
| CN101361934B (en) | Traditional Chinese medicine preparation for treating arthritis and various osteonosus | |
| CN102512566A (en) | Chinese medicine composition for treating kidney deficiency and lumbago | |
| CN103251852B (en) | A kind of medicine coordinating super micro knife to treat osteoarthritis | |
| CN105816613A (en) | Traditional Chinese medicine composition for treating headache caused by liver-yang hyperactivity | |
| CN106266409A (en) | A kind of promoting the flow of QI in the collateral by warming the meridian Chinese medicine external patch and preparation method thereof | |
| CN104524475A (en) | Pharmaceutical preparation for rheumatoid arthritis | |
| CN104606181B (en) | The Isobutyric Acid Thyme separated in Inula nervosa is used for the purposes of Bi condition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170215 |