CN103330806A - Drug for treatment of rheumatoid arthritis - Google Patents

Drug for treatment of rheumatoid arthritis Download PDF

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Publication number
CN103330806A
CN103330806A CN2013102789953A CN201310278995A CN103330806A CN 103330806 A CN103330806 A CN 103330806A CN 2013102789953 A CN2013102789953 A CN 2013102789953A CN 201310278995 A CN201310278995 A CN 201310278995A CN 103330806 A CN103330806 A CN 103330806A
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parts
rhizoma
radix
herba
rheumatoid arthritis
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CN2013102789953A
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CN103330806B (en
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虞攀峰
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Abstract

The invention relates to a drug for treatment of rheumatoid arthritis. The drug is characterized in that it is made of the following raw medicinal materials by weight: 1-3 parts of peach kernels, 2-4 parts of Eucommia ulmoides, 1-5 parts of rhizoma curculiginis, 3-6 parts of long-noded pit viper, 2-5 parts of papayas, 1-6 parts of rhizoma drynariae, 5-8 parts of Radix Astragali, 1-4 parts of spina date seeds, 2-5 parts of Rhodiola rosea, 2-6 parts of asarum, 1-3 parts of myrrh, 3-5 parts of donkey-hide gelatin, 1-4 parts of safflower, 2-5 parts of radix angelicae, 1-6 parts of pyrola, 2-5 parts of black sesame seeds, 1-9 parts of Chinese yam, 1-4 parts of Poria cocos, 1-3 parts of radix sileris, 2-5 parts of notopterygium roots, 2-4 parts of honeysuckle, 1-6 parts of Ligusticum wallichii, 1-3 parts of Salvia miltiorrhiza, 3-5 parts of Lycopodium clavatum, and 1-5 parts of Polygonum cuspidatum. The drug provided in the invention can effectively treat arthralgia and inconvenient flexion and extension caused by rheumatoid arthritis, and also can treat lumbar disc herniation, hyperosteogeny, sciatica and other diseases at the same time.

Description

A kind of medicine that is used for the treatment of rheumatoid arthritis
Technical field
The present invention relates to a kind of medicine for the treatment of rheumatoid arthritis.
 
Background technology
At present, rheumatoid arthritis is a great problem of current rheumatism subject, the morbidity of rheumatoid arthritis is main relevant with factors such as infection, immunity, metabolism, endocrine, environment, heredity, clinical arthralgia, swelling, the moving obstacle of mainly showing as, severe patient the joint can occur and disable and viscera function depletion.Rheumatoid arthritis influences that wrist, the palm refer to, little joint such as proximal interphalangeal joint more, is a plurality of symmetrical distributions, cuts sharp ache, and stiff phenomenon in morning is often arranged.This sick types of drugs of clinical treatment is various, though antiinflammatory action, antiallergic action, calmness, analgesic activity are arranged, improve microcirculation, side effect is big, is not suitable for patient and takes for a long time.
?
Summary of the invention
The objective of the invention is to solve above-mentioned the deficiencies in the prior art, the compound Chinese medicinal preparation of the treatment rheumatoid arthritis of a kind of evident in efficacy, safe, inexpensive, dispelling wind and removing obstruction in the collateral, expelling wind and removing dampness, dispersing cold for relieving pain, nourshing blood and promoting blood circulation, stasis-dispelling and pain-killing, removing dampness circulation of qi promoting is provided.
The present invention relates to a kind of Chinese medicine preparation for the treatment of rheumatoid arthritis, it is characterized in that it being to be made by following parts by weight of traditional Chinese medicines raw material: Semen Persicae 1-3 part, Cortex Eucommiae 2-4 part, Rhizoma Curculiginis 1-5 part, Agkistrodon 3-6 part, Fructus Chaenomelis 2-5 part, Rhizoma Drynariae 1-6 part, Radix Astragali 5-8 part, Semen Ziziphi Spinosae 1-4 part, Radix Rhodiolae 2-5 part, Herba Asari 2-6 part, Myrrha 1-3 part, Colla Corii Asini 3-5 part, Flos Carthami 1-4 part, Radix Angelicae Dahuricae 2-5 part, Herba Pyrolae 1-6 part, Semen Sesami Nigrum 2-5 part, Rhizoma Dioscoreae 1-9 part, Poria 1-4 part, Radix Saposhnikoviae 1-3 part, Rhizoma Et Radix Notopterygii 2-5 part, Flos Lonicerae 2-4 part, Rhizoma Chuanxiong 1-6 part, Radix Salviae Miltiorrhizae 1-3 part, Herba Lycopodii 3-5 part, Rhizoma Polygoni Cuspidati 1-5 part; Preferred especially: 2 parts in Semen Persicae, 2 parts of the Cortexs Eucommiae, 1 part of Rhizoma Curculiginis, 3 parts of Agkistrodons, 2 parts of Fructus Chaenomeliss, 1 part of Rhizoma Drynariae, 5 parts of the Radixs Astragali, 2 parts of Semen Ziziphi Spinosaes, 2 parts of Radix Rhodiolaes, 3 parts of Herba Asaris, 1 part of Myrrha, 3 parts in Colla Corii Asini, 2 parts on Flos Carthami, 3 parts of the Radixs Angelicae Dahuricae, 1 part of Herba Pyrolae, 3 parts of Semen Sesami Nigrums, 2 parts of Rhizoma Dioscoreaes, 2 parts in Poria, 1 part of Radix Saposhnikoviae, 2 parts of Rhizoma Et Radix Notopterygiis, 2 parts of Flos Loniceraes, 4 parts of Rhizoma Chuanxiongs, 2 parts of Radix Salviae Miltiorrhizaes, 3 parts of Herba Lycopodiis, 1 part of Rhizoma Polygoni Cuspidati.
Manufacture method of the present invention: with Semen Persicae, the Cortex Eucommiae, Rhizoma Curculiginis, Agkistrodon, Fructus Chaenomelis, Rhizoma Drynariae, the Radix Astragali, Semen Ziziphi Spinosae, Radix Rhodiolae, Herba Asari, Myrrha, Colla Corii Asini, Flos Carthami, the Radix Angelicae Dahuricae, Herba Pyrolae, Semen Sesami Nigrum, Rhizoma Dioscoreae, Poria, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Flos Lonicerae, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Herba Lycopodii, Rhizoma Polygoni Cuspidati by the proportioning mix homogeneously of getting it filled, pulverized the 60-100 mesh sieve, can be made into powder routinely, or add adjuvant routinely and make honeyed pill, water pill, the present invention is preferably powder, after being ground into the Chinese medicine powder sterilization of smalls, incapsulate every capsules 0.45 gram.
Instructions of taking: every day oral drug dose be 4.05 the gram, divide every day early, middle and late three times oral, each 3.
Medicine of the present invention has the effect of expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, can treat arthralgia and joint stuffiness that rheumatoid joint causes effectively, simultaneously, can also treat diseases such as prolapse of lumbar intervertebral disc, hyperosteogeny, sciatica, have advantages such as evident in efficacy, safe, inexpensive, dispelling wind and removing obstruction in the collateral, expelling wind and removing dampness, dispersing cold for relieving pain, nourshing blood and promoting blood circulation, stasis-dispelling and pain-killing, removing dampness circulation of qi promoting.
The clinical efficacy for the treatment of rheumatism atrophic arthritis is summed up:
One, physical data
Through 7900 routine clinical treatments, rheumatic sufferers 6937 examples wherein, rheumatoid patient 963 examples are simultaneously with 816 examples that have of prolapse of lumbar intervertebral disc, with 1197 examples that have of hyperosteogeny.
Two, diagnostic criteria
Arthralgia, swelling, the severe patient ankylosis, deformity and dysfunction, lab testing, erythrocyte sedimentation rate, rheumatoid factor, X ray examination etc. can be made a definite diagnosis.
Three, instructions of taking
Take compound preparation of the present invention, divide every day early, middle and late three times, each 3, one month is a course for the treatment of.
Four, efficacy assessment standard:
Cure arthralgia, swelling disappears, and recovers all activities.
The improvement arthralgia, swelling alleviates, and joint movement function improves.
More symptom and sign does not have improvement.
Five, therapeutic effect
A month course for the treatment of, course for the treatment of of the lighter, weight person can take a turn for the better or cure two to three courses for the treatment of.
Among the 7900 routine patients, cure 6356 examples, 1544 examples that take a turn for the better, cure rate 80.5%, improvement rate 19.5%, effective percentage 100%.
Six, model case
1. patient Wang Xue, the woman, 38 years old, the Gu Mo of Weihai City people from village, main suit's both hands arthralgia, swelling is surplus March, is diagnosed as rheumatic arthritis through municipal hospital, once medicines such as oral diclofenac sodium, indometacin, pain recurs again after the drug withdrawal, take course for the treatment of of the present invention, not recurrence in a year is followed up a case by regular visits in the symptom complete obiteration.
2. patient Liu Lichen, man, 48 years old, grass mausoleum, Weihai City Ziren, main suit's finger-joint pain 3 years, with prolapse of lumbar intervertebral disc more than a year simultaneously, various big hospital was all once treated in Weihai, at last still taking analgesic, after the drug withdrawal lumbago and joints of hand again pain unbearably, upon somebody's introduction, beginning to take a this product symptom course for the treatment of obviously improves, after continue to take two courses for the treatment of, the symptom complete obiteration is recurrence existing half a year.
3. patient Miao Fengji, the man, 56 years old, people from urban district, Weihai, main suit's joints of hand, the gonalgia are many half a year, knee joint swelling simultaneously, from obeying indometacin, effect is general at ordinary times, come my treatment upon somebody's introduction, take course for the treatment of of the present invention, again from having obeyed a course for the treatment of, do not recur so far after the symptom complete obiteration.
The specific embodiment
Embodiment 1: get Semen Persicae 2g, Cortex Eucommiae 2g, Rhizoma Curculiginis 1g, Agkistrodon 3g, Fructus Chaenomelis 2g, Rhizoma Drynariae 1g, Radix Astragali 5g, Semen Ziziphi Spinosae 2g, Radix Rhodiolae 2g, Herba Asari 3g, Myrrha 1g, Colla Corii Asini 3g, Flos Carthami 2g, Radix Angelicae Dahuricae 3g, Herba Pyrolae 1g, Semen Sesami Nigrum 3g, Rhizoma Dioscoreae 2g, Poria 2g, Radix Saposhnikoviae 1g, Rhizoma Et Radix Notopterygii 2g, Flos Lonicerae 2g, Rhizoma Chuanxiong 4g, Radix Salviae Miltiorrhizae 2g, Herba Lycopodii 3g, Rhizoma Polygoni Cuspidati 1g, behind these Chinese medicine mix homogeneously, pulverized the 60-100 mesh sieve, can be made into powder routinely, or add adjuvant routinely and make honeyed pill, water pill, every day, oral drug dose was 4.05 grams, divide every day early, in, the evening three times oral, each 1.35 grams, one after each meal, the present invention preferably makes powder with medicine, incapsulate after the sterilization, every 0.45 gram divides early every day, in, the evening three times oral, each 3, one after each meal.

Claims (2)

1. a medicine for the treatment of rheumatoid arthritis is characterized in that it being to be made by following parts by weight of traditional Chinese medicines raw material: Semen Persicae 1-3 part, Cortex Eucommiae 2-4 part, Rhizoma Curculiginis 1-5 part, Agkistrodon 3-6 part, Fructus Chaenomelis 2-5 part, Rhizoma Drynariae 1-6 part, Radix Astragali 5-8 part, Semen Ziziphi Spinosae 1-4 part, Radix Rhodiolae 2-5 part, Herba Asari 2-6 part, Myrrha 1-3 part, Colla Corii Asini 3-5 part, Flos Carthami 1-4 part, Radix Angelicae Dahuricae 2-5 part, Herba Pyrolae 1-6 part, Semen Sesami Nigrum 2-5 part, Rhizoma Dioscoreae 1-9 part, Poria 1-4 part, Radix Saposhnikoviae 1-3 part, Rhizoma Et Radix Notopterygii 2-5 part, Flos Lonicerae 2-4 part, Rhizoma Chuanxiong 1-6 part, Radix Salviae Miltiorrhizae 1-3 part, Herba Lycopodii 3-5 part, Rhizoma Polygoni Cuspidati 1-5 part.
2. medicine as claimed in claim 1 is characterized in that it being to be made by following parts by weight of traditional Chinese medicines raw material: 2 parts in Semen Persicae, 2 parts of the Cortexs Eucommiae, 1 part of Rhizoma Curculiginis, 3 parts of Agkistrodons, 2 parts of Fructus Chaenomeliss, 1 part of Rhizoma Drynariae, 5 parts of the Radixs Astragali, 2 parts of Semen Ziziphi Spinosaes, 2 parts of Radix Rhodiolaes, 3 parts of Herba Asaris, 1 part of Myrrha, 3 parts in Colla Corii Asini, 2 parts on Flos Carthami, 3 parts of the Radixs Angelicae Dahuricae, 1 part of Herba Pyrolae, 3 parts of Semen Sesami Nigrums, 2 parts of Rhizoma Dioscoreaes, 2 parts in Poria, 1 part of Radix Saposhnikoviae, 2 parts of Rhizoma Et Radix Notopterygiis, 2 parts of Flos Loniceraes, 4 parts of Rhizoma Chuanxiongs, 2 parts of Radix Salviae Miltiorrhizaes, 3 parts of Herba Lycopodiis, 1 part of Rhizoma Polygoni Cuspidati.
CN201310278995.3A 2013-07-04 2013-07-04 Drug for treatment of rheumatoid arthritis Expired - Fee Related CN103330806B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550741A (en) * 2013-10-31 2014-02-05 谢坤 Traditional Chinese medicinal preparation for treating rheumatism
CN103735848A (en) * 2014-01-24 2014-04-23 袁延光 Traditional Chinese medicine preparation for treating osteoproliferation and preparation method of traditional Chinese medicine preparation
CN104189357A (en) * 2014-08-18 2014-12-10 杨海林 Traditional Chinese medicine ointment for treating rheumatoid arthritis
CN104524077A (en) * 2014-12-22 2015-04-22 蒋亚静 Traditional Chinese medicine capsule for treating sciatica and preparation method of traditional Chinese medicine capsule
CN104840624A (en) * 2015-05-27 2015-08-19 石汝花 Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof
CN107184648A (en) * 2017-06-02 2017-09-22 广州智润生物制药科技有限公司 It is a kind of to treat patch of protrusion of lumber intervertebral disc and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450184A (en) * 2007-12-06 2009-06-10 陈振山 Plaster for treating rheumatism bone disease
CN101632745A (en) * 2009-09-08 2010-01-27 方建超 Traditional Chinese medical compound preparation for treating rheumatism and rheumatoid arthritis
CN102366602A (en) * 2011-10-21 2012-03-07 铜仁市舒心科技有限责任公司 Traditional Chinese medicine formula used for treating rheumatism

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450184A (en) * 2007-12-06 2009-06-10 陈振山 Plaster for treating rheumatism bone disease
CN101632745A (en) * 2009-09-08 2010-01-27 方建超 Traditional Chinese medical compound preparation for treating rheumatism and rheumatoid arthritis
CN102366602A (en) * 2011-10-21 2012-03-07 铜仁市舒心科技有限责任公司 Traditional Chinese medicine formula used for treating rheumatism

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
安莉萍等: "补益肝肾法为主治疗类风湿性关节炎近况", 《中国康复理论与实践》, no. 2, 28 February 2008 (2008-02-28) *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550741A (en) * 2013-10-31 2014-02-05 谢坤 Traditional Chinese medicinal preparation for treating rheumatism
CN103735848A (en) * 2014-01-24 2014-04-23 袁延光 Traditional Chinese medicine preparation for treating osteoproliferation and preparation method of traditional Chinese medicine preparation
CN104189357A (en) * 2014-08-18 2014-12-10 杨海林 Traditional Chinese medicine ointment for treating rheumatoid arthritis
CN104524077A (en) * 2014-12-22 2015-04-22 蒋亚静 Traditional Chinese medicine capsule for treating sciatica and preparation method of traditional Chinese medicine capsule
CN104840624A (en) * 2015-05-27 2015-08-19 石汝花 Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof
CN107184648A (en) * 2017-06-02 2017-09-22 广州智润生物制药科技有限公司 It is a kind of to treat patch of protrusion of lumber intervertebral disc and preparation method thereof

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