CN104161868A - Drug for treating rheumatoid arthritis - Google Patents
Drug for treating rheumatoid arthritis Download PDFInfo
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- CN104161868A CN104161868A CN201410345420.3A CN201410345420A CN104161868A CN 104161868 A CN104161868 A CN 104161868A CN 201410345420 A CN201410345420 A CN 201410345420A CN 104161868 A CN104161868 A CN 104161868A
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, aims to treat rheumatoid arthritis, and provides a drug for treating rheumatoid arthritis. The drug is composed of the following raw materials according to a certain ratio: radix codonopsis, radix astragali, poria cocos, bighead atractylodes rhizome, cassia twig, Chinese angelica, achyranthes root, stephania terandra, spatholobus stem, Chinese starjasmine stem, clematis root, rhizoma atractylodis, golden cypress, peach seed, safflower, angelicae pubescentis, and earthworm. The application method comprises the following steps: adding 700 mL of water into a first decoction comprising the raw materials mentioned above, decocting until 200 mL of water is left; adding 500 mL of water into a second decoction, decocting until 200 mL of water is left; and orally taking the decoction twice a day on an empty stomach, one in the morning, and the other in the evening. In the traditional Chinese medicine preparation, the radix codonopsis, radix astragali, poria cocos, and bighead atractylodes rhizome has the functions of invigorating the spleen and boosting qi; cassia twig, and Chinese angelica has the functions of warming the meridian and dispelling cold; achyranthes root, stephania terandra, spatholobus stem, Chinese starjasmine stem, clematis root, rhizoma atractylodis, golden cypress, peach seed, safflower, angelicae pubescentis, and earthworm has the functions of dispelling wind, draining dampness, activating blood, and freeing the collaterals; the raw materials mentioned above are scientifically compounded to generate a synergetic effect, and the drug has a very good effect on treating rheumatoid arthritis.
Description
technical field:
the present invention relates to a kind of Chinese medicine (belonging to technical field of Chinese medicines), particularly relate to a kind of medicine that is used for the treatment of rheumatoid arthritis.
background technology:
rheumatoid arthritis is a kind of autoimmune disease that symmetry polyarthritis is main manifestations of take, and it is principal character that the carrying out property in synovitis and joint of take is destroyed.This disease is apt to occur in the little joints such as hands, wrist, foot, and outbreak, is symmetric repeatedly.Have in early days joint red and swollen heat pain and dysfunction, can there is stiff deformity in various degree in joint late period, and with the atrophy of bone and bones flesh, very easily disable.The general performance of rheumatoid arthritis, except arthropathy, also has heating, fatigue and weak, pericarditis, subcutaneous nodule, pleuritis, arteritis, peripheral neuropathy etc.Primary disease belongs to the categories such as Chinese medicine " arthromyodynia ", " severe and migratory arthralgia ", " rheumatoid arthritis ".The pathogen such as wind, cold, wet, heat impatency meridians, affect QI-blood circulation, cause limbs muscle BJM etc. locate to occur pain, weighing, miserable, numb, or joint joint stuffiness, stiff, enlargement, distortion etc.
treat clinically rheumatoid arthritis comparatively thorny, general treatment oral promoting blood circulation and stopping pain class medicine or containing amcinonide, cures the symptoms, not the disease, and does not reach the object for the treatment of.
summary of the invention:
in order to solve the problem for the treatment of rheumatoid arthritis, provide a kind of medicine that is used for the treatment of rheumatoid arthritis.
technical solution of the present invention is that the Chinese medicine by following weight proportion is that raw material is prepared from:
radix Codonopsis 9-15 part, Radix Astragali 9-15 part, Poria 6-12 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Ramulus Cinnamomi 6-12 part, Radix Angelicae Sinensis 9-15 part, Radix Achyranthis Bidentatae 6-12 part, Radix Stephaniae Tetrandrae 6-12 part, Caulis Spatholobi 12-18 part, Caulis Trachelospermi 6-12 part, Radix Clematidis 6-12 part, Rhizoma Atractylodis 6-12 Fen, Yellow cypress 6-12 part, Semen Persicae 3-9 part, Flos Carthami 3-9 part, Radix Angelicae Pubescentis 6-12 part, Pheretima 6-12 part, above-mentioned every part are 1 gram.
medicine optimum weight proportioning of the present invention is:
12 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 9 parts, Poria, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Ramulus Cinnamomi, 12 parts of Radix Angelicae Sinensis, 9 parts of Radix Achyranthis Bidentataes, 9 parts of Radixs Stephaniae Tetrandrae, 15 parts of Caulis Spatholobis, 9 parts of Caulis Trachelospermis, 9 parts of Radix Clematidis, Rhizoma Atractylodis 99 parts of Fen, Yellow cypresses, 6 parts, Semen Persicae, 6 parts, Flos Carthami, 9 parts of Radix Angelicae Pubescentiss, 9 parts of Pheretimas, above-mentioned every part are 1 gram.
said medicine can be made to the dosage form any for oral administration on pharmaceutics, the preferred dosage form of the present invention is decoction.
the concrete preparation method of medicine of the present invention is first dose of said medicine to be added to 700 milliliters, water decoct to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters.
using method is by the decoction oral of decocting, every day twice, sooner or later empty clothes.
the traditional Chinese medical science is thought: it is Therapeutic Principle that rheumatoid arthritis should be take invigorating the spleen and benefiting QI, dispelling cold by warming the meridian, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Radix Codonopsis, the Radix Astragali, Poria, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI in side; Ramulus Cinnamomi, Radix Angelicae Sinensis dispelling cold by warming the meridian; Radix Achyranthis Bidentatae, Radix Stephaniae Tetrandrae, Caulis Spatholobi, Caulis Trachelospermi, Radix Clematidis, Rhizoma Atractylodis, Yellow cypress, Semen Persicae, Flos Carthami, Radix Angelicae Pubescentis, Pheretima expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral; Said medicine compatibility is used, synergism, thus reach the object for the treatment of.
curative effect of medication of the present invention is good, instant effect, taking convenience, have no side effect, and rheumatoid arthritis is had to good therapeutic effect.
for further clinical efficacy and the safety of proof medicine of the present invention.Select 200 routine patients to carry out clinical observation to medicine of the present invention.
example patient in, within 15 days, be a course for the treatment of, one the course for the treatment of cured person 100 examples, two the course for the treatment of cured person 60 examples, two the course for the treatment of above cured person 36 examples, invalid 4 examples.All use the present invention to treat, every day potion, every day twice, sooner or later empty clothes.
criterion of therapeutical effect: effective: arthralgia, joint joint stuffiness, stiff, enlargement transference cure; Effective: arthralgia, joint joint stuffiness, stiff, enlargement symptom are extenuated or disappear; Invalid: treatment front and back are without significant change.
statistical result after table 1 treatment
| Patient | Number of cases | Effective (%) | Effectively (%) | Invalid (%) | Total effective rate (%) |
| One the course for the treatment of cured person | 100 | 80（80） | 20(20) | 0(0) | 100（100） |
| Two the course for the treatment of cured person | 60 | 52（86.6） | 8(13.4) | 0(0) | 60（100） |
| Two the course for the treatment of above cured person | 40 | 16（40） | 20(50) | 4(10) | 36（90） |
| Amount to | 200 | 148（74） | 48（24） | 4(2) | 196（98） |
the specific embodiment:
embodiment 1:
a medicine that is used for the treatment of rheumatoid arthritis is that the Chinese medicine by following weight proportion is that raw material is prepared from:
15 parts of Radix Codonopsis, 15 parts of the Radixs Astragali, 12 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Ramulus Cinnamomi, 15 parts of Radix Angelicae Sinensis, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radixs Stephaniae Tetrandrae, 18 parts of Caulis Spatholobis, 12 parts of Caulis Trachelospermis, 12 parts of Radix Clematidis, Rhizoma Atractylodis 12 12 parts of Fen, Yellow cypresses, 9 parts, Semen Persicae, 9 parts, Flos Carthami, 12 parts of Radix Angelicae Pubescentiss, 12 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
case 1.
wang, man, 38 years old,, there is arthralgia after readme cause half a year is affected by the cold in first visit on March 28 in 2011, over the past half year whenever YIN-cold weather pain increase the weight of, two knee joint pain is obviously with biped swelling recently.Medical history, healthy.
indagation: double knee joint pain, hands and feet being not warm or biped swelling, easily sweating, pale tongue with thin fur is white.Be diagnosed as " rheumatoid arthritis ".
prescription: 15 parts of Radix Codonopsis, 15 parts of the Radixs Astragali, 12 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Ramulus Cinnamomi, 15 parts of Radix Angelicae Sinensis, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radixs Stephaniae Tetrandrae, 18 parts of Caulis Spatholobis, 12 parts of Caulis Trachelospermis, 12 parts of Radix Clematidis, Rhizoma Atractylodis 12 12 parts of Fen, Yellow cypresses, 9 parts, Semen Persicae, 9 parts, Flos Carthami, 12 parts of Radix Angelicae Pubescentiss, 12 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
two examine: take medicine of the present invention after the course for the treatment of, arthralgia significantly alleviates, but feel lassitude of the limbs and weakness.
prescription: 15 parts of Radix Codonopsis, 15 parts of the Radixs Astragali, 12 parts, Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Ramulus Cinnamomi, 15 parts of Radix Angelicae Sinensis, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radixs Stephaniae Tetrandrae, 18 parts of Caulis Spatholobis, 12 parts of Caulis Trachelospermis, 12 parts of Radix Clematidis, Rhizoma Atractylodis 12 12 parts of Fen, Yellow cypresses, 9 parts, Semen Persicae, 9 parts, Flos Carthami, 12 parts of Radix Angelicae Pubescentiss, 12 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
three examine: joint not bitterly, continues to strengthen and takes a course for the treatment of of medicine of the present invention, after half a year, visit, and joint is pain mistake not again, clinical recovery.
embodiment 2:
a medicine that is used for the treatment of rheumatoid arthritis is that the Chinese medicine by following weight proportion is that raw material is prepared from:
12 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 9 parts, Poria, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Ramulus Cinnamomi, 12 parts of Radix Angelicae Sinensis, 9 parts of Radix Achyranthis Bidentataes, 9 parts of Radixs Stephaniae Tetrandrae, 15 parts of Caulis Spatholobis, 9 parts of Caulis Trachelospermis, 9 parts of Radix Clematidis, Rhizoma Atractylodis 99 parts of Fen, Yellow cypresses, 6 parts, Semen Persicae, 6 parts, Flos Carthami, 9 parts of Radix Angelicae Pubescentiss, 9 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
case 2.
garden, female, 58 years old, JIUYUE in 2012 first visit on the 8th, rheumatoid arthritis history 3 years,
indagation: arthralgia is obvious, joints of hand swelling distortion, extremities joint swells and ache, and with lower limb ankle, for very, pale tongue with thin fur is white.
prescription: 12 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 9 parts, Poria, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Ramulus Cinnamomi, 12 parts of Radix Angelicae Sinensis, 9 parts of Radix Achyranthis Bidentataes, 9 parts of Radixs Stephaniae Tetrandrae, 15 parts of Caulis Spatholobis, 9 parts of Caulis Trachelospermis, 9 parts of Radix Clematidis, Rhizoma Atractylodis 99 parts of Fen, Yellow cypresses, 6 parts, Semen Persicae, 6 parts, Flos Carthami, 9 parts of Radix Angelicae Pubescentiss, 9 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
two examine: take medicine of the present invention after the course for the treatment of, joint of the lower extremity pain and swelling alleviates, and diet two is just as usual, and pale tongue with thin fur is white.
prescription: 12 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 9 parts, Poria, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Ramulus Cinnamomi, 12 parts of Radix Angelicae Sinensis, 9 parts of Radix Achyranthis Bidentataes, 9 parts of Radixs Stephaniae Tetrandrae, 15 parts of Caulis Spatholobis, 9 parts of Caulis Trachelospermis, 9 parts of Radix Clematidis, Rhizoma Atractylodis 99 parts of Fen, Yellow cypresses, 6 parts, Semen Persicae, 6 parts, Flos Carthami, 9 parts of Radix Angelicae Pubescentiss, 9 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
three examine: take medicine of the present invention after two courses for the treatment of, all diseases subtract greatly, after half a year, visit, and symptom is not sent out.
embodiment 3:
a medicine that is used for the treatment of rheumatoid arthritis is that the Chinese medicine by following weight proportion is that raw material is prepared from:
9 parts of Radix Codonopsis, 9 parts of the Radixs Astragali, 6 parts, Poria, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Ramulus Cinnamomi, 9 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 6 parts of Radixs Stephaniae Tetrandrae, 12 parts of Caulis Spatholobis, 6 parts of Caulis Trachelospermis, 6 parts of Radix Clematidis, Rhizoma Atractylodis 66 parts of Fen, Yellow cypresses, 3 parts, Semen Persicae, 3 parts, Flos Carthami, 6 parts of Radix Angelicae Pubescentiss, 6 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
case 3.
season, female, 73 years old, first visit on August 28 in 2011, double knee joint pain and swelling, meets cold play, get Re Zeshu, diet two is just as usual, and Western medicine diagnose is " rheumatoid arthritis ".
prescription: 9 parts of Radix Codonopsis, 9 parts of the Radixs Astragali, 6 parts, Poria, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Ramulus Cinnamomi, 9 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 6 parts of Radixs Stephaniae Tetrandrae, 12 parts of Caulis Spatholobis, 6 parts of Caulis Trachelospermis, 6 parts of Radix Clematidis, Rhizoma Atractylodis 66 parts of Fen, Yellow cypresses, 3 parts, Semen Persicae, 3 parts, Flos Carthami, 6 parts of Radix Angelicae Pubescentiss, 6 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
two examine: take medicine of the present invention after the course for the treatment of, lower extremity swelling and distension significantly alleviates, but feel that limb is soft, fear of cold, and diet two is just as usual.
prescription: 9 parts of Radix Codonopsis, 9 parts of the Radixs Astragali, 6 parts, Poria, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Ramulus Cinnamomi, 9 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 6 parts of Radixs Stephaniae Tetrandrae, 12 parts of Caulis Spatholobis, 6 parts of Caulis Trachelospermis, 6 parts of Radix Clematidis, Rhizoma Atractylodis 66 parts of Fen, Yellow cypresses, 3 parts, Semen Persicae, 3 parts, Flos Carthami, 6 parts of Radix Angelicae Pubescentiss, 6 parts of Pheretimas, above-mentioned every part are 1 gram.
after will said medicine mixing, decoct into decoction, first dose adds 700 milliliters, water and decocts to 200 milliliters, and second dose adds 500 milliliters, water and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
three examine: take medicine of the present invention after the course for the treatment of, symptom disappears entirely, after half a year, visits, and symptom is not sent out.
Claims (3)
1. a medicine that is used for the treatment of rheumatoid arthritis, is characterized in that, by the medicine of following weight proportion, is made:
Radix Codonopsis 9-15 part, Radix Astragali 9-15 part, Poria 6-12 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Ramulus Cinnamomi 6-12 part, Radix Angelicae Sinensis 9-15 part, Radix Achyranthis Bidentatae 6-12 part, Radix Stephaniae Tetrandrae 6-12 part, Caulis Spatholobi 12-18 part, Caulis Trachelospermi 6-12 part, Radix Clematidis 6-12 part, Rhizoma Atractylodis 6-12 Fen, Yellow cypress 6-12 part, Semen Persicae 3-9 part, Flos Carthami 3-9 part, Radix Angelicae Pubescentis 6-12 part, Pheretima 6-12 part, above-mentioned every part are 1 gram.
2. a kind of medicine that is used for the treatment of rheumatoid arthritis according to claim 1, is characterized in that, by the medicine of following weight proportion, is made:
12 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 9 parts, Poria, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Ramulus Cinnamomi, 12 parts of Radix Angelicae Sinensis, 9 parts of Radix Achyranthis Bidentataes, 9 parts of Radixs Stephaniae Tetrandrae, 15 parts of Caulis Spatholobis, 9 parts of Caulis Trachelospermis, 9 parts of Radix Clematidis, Rhizoma Atractylodis 99 parts of Fen, Yellow cypresses, 6 parts, Semen Persicae, 6 parts, Flos Carthami, 9 parts of Radix Angelicae Pubescentiss, 9 parts of Pheretimas, above-mentioned every part are 1 gram.
3. according to a kind of medicine that is used for the treatment of rheumatoid arthritis described in claim 1,2, it is characterized in that described medicine with being decocted in water for oral dose into decoction oral.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410345420.3A CN104161868A (en) | 2014-07-21 | 2014-07-21 | Drug for treating rheumatoid arthritis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410345420.3A CN104161868A (en) | 2014-07-21 | 2014-07-21 | Drug for treating rheumatoid arthritis |
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| CN104161868A true CN104161868A (en) | 2014-11-26 |
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| CN201410345420.3A Pending CN104161868A (en) | 2014-07-21 | 2014-07-21 | Drug for treating rheumatoid arthritis |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547740A (en) * | 2014-12-29 | 2015-04-29 | 丁鸿磊 | Traditional Chinese medicine for treating rheumatism and preparation method of traditional Chinese medicine |
| CN105213589A (en) * | 2015-11-11 | 2016-01-06 | 洪思滨 | A kind of Chinese medicine formula for the treatment of rheumatoid arthritis |
| CN105748543A (en) * | 2016-04-29 | 2016-07-13 | 重庆市中药研究院 | Traditional Chinese medicine composition for treating rheumatic disease and preparing method of traditional Chinese medicine composition |
| CN106214952A (en) * | 2016-08-24 | 2016-12-14 | 沈友良 | A kind of pharmaceutical composition treating rheumatoid arthritis |
| CN108619464A (en) * | 2018-08-17 | 2018-10-09 | 陈楚翁 | A kind of Chinese medicine composition and preparation method and application for treating rheumatoid arthritis |
| IT201800020053A1 (en) * | 2018-12-18 | 2020-06-18 | Shanghai Boling Man Cosmetic Co Ltd | Drug for the treatment of shoulder periarthritis and method for its preparation |
-
2014
- 2014-07-21 CN CN201410345420.3A patent/CN104161868A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547740A (en) * | 2014-12-29 | 2015-04-29 | 丁鸿磊 | Traditional Chinese medicine for treating rheumatism and preparation method of traditional Chinese medicine |
| CN104547740B (en) * | 2014-12-29 | 2018-05-29 | 丁鸿磊 | It is a kind of to be used to treat Chinese medicine of rheumatism and preparation method thereof |
| CN105213589A (en) * | 2015-11-11 | 2016-01-06 | 洪思滨 | A kind of Chinese medicine formula for the treatment of rheumatoid arthritis |
| CN105748543A (en) * | 2016-04-29 | 2016-07-13 | 重庆市中药研究院 | Traditional Chinese medicine composition for treating rheumatic disease and preparing method of traditional Chinese medicine composition |
| CN106214952A (en) * | 2016-08-24 | 2016-12-14 | 沈友良 | A kind of pharmaceutical composition treating rheumatoid arthritis |
| CN108619464A (en) * | 2018-08-17 | 2018-10-09 | 陈楚翁 | A kind of Chinese medicine composition and preparation method and application for treating rheumatoid arthritis |
| CN108619464B (en) * | 2018-08-17 | 2021-03-16 | 陈楚翁 | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method and application thereof |
| IT201800020053A1 (en) * | 2018-12-18 | 2020-06-18 | Shanghai Boling Man Cosmetic Co Ltd | Drug for the treatment of shoulder periarthritis and method for its preparation |
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Application publication date: 20141126 |