CN106377741A - Traditional Chinese medicine for treating infertility and preparation method thereof - Google Patents

Traditional Chinese medicine for treating infertility and preparation method thereof Download PDF

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CN106377741A
CN106377741A CN201610854501.5A CN201610854501A CN106377741A CN 106377741 A CN106377741 A CN 106377741A CN 201610854501 A CN201610854501 A CN 201610854501A CN 106377741 A CN106377741 A CN 106377741A
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infertility
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魏庆
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Abstract

The invention relates to a traditional Chinese medicine for treating infertility and a preparation method thereof. The traditional Chinese medicine for treating infertility is a traditional Chinese medicine composition which is prepared from cassia twigs, radix paeoniae alba, roasted radix codonopsis, fructus evodiae, rhizoma chuanxiong, radix angelicae sinensis, root barks of tree peony, ginger, rhizoma pinellinae praeparata, radix ophiopogonis and the like through boiling, auxiliary material addition, spray-drying and the like. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicines selected in the formula of the invention have effects of circulating qi and activating blood, have specific effects on infertility caused by disorder qi and blood of females, and also have effects of boosting and enriching essence, inducing dieresis, tonifying kidney yang and nourishing kidneys of males. On the basis of traditional Chinese medicines, the traditional Chinese medicine is capable of regulating qi and blood of human bodies, improving the immunity of the human bodies and enriching the vitality of bodies, so that a patient has a good fertilization internal environment, and the probability of fertilization can be increased; and as the immunity of the bodies is improved, the body recovery property can be improved, and the function state of prostate tissue can be improved.

Description

Chinese medicine for the treatment of sterility and infertility and preparation method thereof
Technical field
The invention belongs to a kind of field of pharmaceutical technology is and in particular to a kind of Chinese medicine treating sterility and infertility and its preparation side Method.
Background technology
Infertility and infertility are referred to as sterility and infertility.Couple normally have sexual intercourse more than 1 year, and do not adopt artificial hand Section contraception is it is impossible to the situation of successful pregnancies just belongs to infertility.Typically, if the problem on the wife's side and could not pregnancy just by Referred to as infertility is although become pregnant in the wife's side, but last or miscarriage, not if the lower baby of success birth, thus referred to as sterile Disease.
The investigation of World Health Organization (WHO) confirms:Infertility has become as continue in the world at present tumor and cardiovascular and cerebrovascular disease The third-largest disease afterwards.At present, there is the couple at child-bearing age about 2.3 hundred million people in the whole nation, sterility and infertility incidence rate probably 15% to 20%, That is at least 10,000,000 families are perplexed by a fertility difficult problem.Expect the 40%-50% of the year two thousand fifty women of child-bearing age and incite somebody to action The nearly male of more than half will be the victim of sterility and infertility.
Many medicines are used for treating infertility, and wherein the overwhelming majority is by setting up normal ovulation, increase follicle quantity, control Ovulation period, preparation plantation inner membrance and embryo support are developed and are promoted pregnancy, but large side effects, generation are concurrent for women Disease, such as ovarian hyperstimulation syndrome, serious clinical manifestation is exactly that abdominal distention, stomachache, dyspnea and ovary increase.Mesh The medicine of front most for the treatment of male infertility has a lot, but big multi objective does not effect a permanent cure, or price is higher, and patient can not hold It is subject to, or side effect is larger, patient is impatient at.
Content of the invention
In order to solve the problems referred to above of prior art presence, the invention provides a kind of Chinese medicine treating sterility and infertility and its Preparation method, according to traditional Chinese medicine theory, makes in conjunction with modern pharmaceutical technology, has preferable treatment to curing " sterility and infertility " Effect, and have no toxic side effect.
The technical solution adopted in the present invention is:A kind of Chinese medicine treating sterility and infertility, including the raw material of following weight portion: Ramulus Cinnamomi 3-7 part, Radix Paeoniae Alba 3-7 part, process Radix Codonopsis 3-7 part, Radix Glycyrrhizae Preparata 0.5-1.5 part, Fructus Evodiae 1-3 part, Rhizoma Chuanxiong 1-3 part, Radix Angelicae Sinensis 2-4 Part, Cortex Moutan 3-5 part, Rhizoma Zingiberis Recenss 3-7 part, Rhizoma Pinelliae Preparatum 3-7 part, 3-7 part Radix Ophiopogonis, Radix Dipsaci 3-5 part, Fructus Leonuri 3-5 part, Semen Cuscutae 3-7 Part, Cornu Cervi 1-3 part.
Further, including the raw material of following weight portion:5 parts of Ramulus Cinnamomi, 5 parts of the Radix Paeoniae Alba, process 5 parts of Radix Codonopsis, 1 part of Radix Glycyrrhizae Preparata, Wu 2 parts of the Fructus Evodiae, 2 parts of Rhizoma Chuanxiong, 3 parts of Radix Angelicae Sinensis, 4 parts of Cortex Moutan, 5 parts of Rhizoma Zingiberis Recenss, 5 parts of Rhizoma Pinelliae Preparatum, 5 parts of Radix Ophiopogonis, 4 parts of Radix Dipsaci, 4 parts of Fructus Leonuri, 5 parts of Semen Cuscutae, 2 parts of Cornu Cervi.
A kind of preparation method of the described Chinese medicine for the treatment of sterility and infertility, comprises the following steps:
(1) pre-treatment:By Ramulus Cinnamomi, the Radix Paeoniae Alba, process Radix Codonopsis, Fructus Evodiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Cortex Moutan, Rhizoma Zingiberis Recenss, Rhizoma Pinelliae Preparatum, Radix Ophiopogonis, Radix Dipsaci and Cornu Cervi are pulverized, and form Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss Block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block;
(2) mix:By described Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, life Rhizoma Zingiberis Recens block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are mixed with Radix Glycyrrhizae Preparata, Fructus Leonuri, Semen Cuscutae, mix homogeneously shape Become compound;
(3) cook:With 8-10 times of the weight of described compound of water, described compound is first soaked, then boiled 2-5 hour processed, first uses slow fire infusion with after big fire decoction in boiling process, is finally concentrated with moderate heat again, filter after precipitation, Discard material residue and obtain feed liquid;
(4) add adjuvant:Add in the described feed liquid obtaining in step (3) described feed liquid 5-8% weight starch and The xylitol of described feed liquid 1-3% weight, mix homogeneously makes mixed liquor;
(5) it is spray-dried:Mixed liquor is spray-dried, is obtained hybrid particles, i.e. finished product.
Further, Ramulus Cinnamomi block, Radix Paeoniae Alba block described in step (1), process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are length and width, the thick side being less than 0.5 centimetre Block.
Further, soaking described in step (3) is immersion 5-8 hour at 35-60 DEG C.
Further, the temperature of big fire described in step (3) is 85-93 DEG C, and the time of described decoction is 1-2 hour;Institute The temperature stating slow fire is 60-70 DEG C, and the time of described infusion is 1-2 hour;The temperature of described moderate heat is 75-80 DEG C, described dense The time of contracting is 40-60 minute.
Further, the brew time described in step (3) is 3 hours, and the time of wherein said decoction is little for 1.5 When, the time of described infusion is 1.5 hours;The time of described concentration is 50 minutes.
Further, the addition of starch described in step (4) is the 6% of described feed liquid weight, the adding of described xylitol Dosage is the 2% of described feed liquid weight.
Further, the temperature being spray-dried described in step (5) is 65-80 DEG C, and the particle diameter of described hybrid particles is 500-900μm.
Major part in Chinese medicine raw material used when producing of the treatment sterility and infertility of the present invention be process through specification plus " prepared slices of Chinese crude drugs " after work.Hereinafter, raw materials used property in the present invention etc. is slightly explained:
Ramulus Cinnamomi, the dry twig of canella Cortex Cinnamomi, acrid, sweet, warm;GUIXIN, lung, bladder warp;There is sweating expelling pathogenic factors from muscles and skin, Wen Tong Passages through which vital energy circulates, helps yang transforming qi, effect of flat gas that spins;Be usually used in anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, Edema, cardiopalmus.
The Radix Paeoniae Alba, is the dry root of ranunculaceae plant Radix Paeoniae Paeonia tacti lora Pall.;There is nourishing blood for regulating menstruation, hold back The effect of cloudy hidroschesis, easing the affected liver to relieve pain, suppressing liver-YANG;Be usually used in blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, four Limb spasm and pain, dizziness of having a headache.The Radix Paeoniae Alba, Ramulus Cinnamomi and Radix Angelicae Sinensis synergism, enhance effect of blood-nourishing blood-generating.
Radix Glycyrrhizae Preparata, is the Radix Glycyrrhizae baked with honey, Radix Glycyrrhizae Preparata has benefiting qi and nourishing yin, activate yang multiple arteries and veins therapeutic efficiency.
Process Radix Codonopsis, also known as processed with honey Radix Codonopsis, after taking the dilution of refined honey certain amount of boiling water, mix thoroughly with Radix Codonopsis piece, vexed, put and propagandize medicine hotly In pot, with slow fire heating, constantly stir-fry to yellowish-brown, take out when tack-free, cool.Typically every 100g Radix Codonopsis piece, uses refined honey 20g, processs Radix Codonopsis and has lung moistening tonifying YIN, effect of invigorating the spleen and replenishing QI.
Fructus Evodiae, be rutaceae Fructus Evodiae, stone tiger or thin hair Fructus Evodiae almost ripe fruit is dried;Pungent, bitter, heat; Slightly poisonous;Return liver, spleen, stomach, kidney channel;Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, cold hernia stomachache, cold-damp Tinea pedis, abdominal pain during menstruation, abdominal distention, vomit acid regurgitation, Diarrhoea.
Rhizoma Chuanxiong:This product is the dry rhizome of samphire Rhizoma Chuanxiong LigusticumchuanxiongHort.;Acrid in the mouth, property Temperature;Return liver, gallbladder, pericardium channel;Blood-activating and qi-promoting, wind-expelling pain-stopping;For obstruction of qi in the chest and cardialgia, chest side of body shouting pain, tumbling and swelling, menoxenia, Closed dysmenorrhea, abdominal mass abdominal mass is suffered from abdominal pain, headache, rheumatic arthralgia.
Radix Angelicae Sinensis, are the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels;There is work of enriching blood The effect of blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation;It is usually used in blood deficiency and yellow complexion, dizziness palpitaition, menoxenia, closed dysmenorrhea, deficiency and coldness abdomen Bitterly, rheumatic arthralgia, injury from falling down, ulcer sores, dry constipation of intestines.
Cortex Moutan:Also known as Cortex Moutan, this product is the dry root of ranunculaceae peony PaeoniasuffruticosaAndr. Skin;Bitter in the mouth, pungent, cold nature;GUIXIN, liver and kidney channel;Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For thermal man's nutrient blood, maculae caused by violent heat pathogen, nosebleed of spitting blood Blood, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, closed dysmenorrhea, the pain of injury caused by falling and tumbling, carbuncle sore tumefacting virus.Cortex Moutan and Fructus Leonuri synergism enhance work Effect of blood blood stasis dispelling.
Rhizoma Zingiberis Recenss, are the new fresh quench stem of zingiber ZingiberofficinaleRosc., acrid in the mouth, slightly warm in nature;Return lung, Spleen, stomach;Relieving exterior syndrome and dispelling cold, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing, solving toxin of fish and crab;For anemofrigid cold, gastrofrigid vomiting, cold-phlegm is coughed, fish Eriocheir sinensiss are poisoned.
Rhizoma Pinelliae Preparatum, is the Preparation process product of the Rhizoma Pinelliae;Acrid in the mouth, warm in nature;Returns spleen, stomach, lung meridian;Drying dampness to eliminate phlegm;Cough for abundant expectoration Breathe heavily, phlegm retention anti-dazzle nervous, dizziness due to wind-phlegm, phlegm and headache.
Radix Ophiopogonis, is the dried root of liliaceous plant Ophiopogonjaponicus Radix Ophiopogonis (L.f) Ker-Gawl.;Taste Sweet, slight bitter, cold nature;GUIXIN, lung, stomach;YIN nourishing and the production of body fluid promoting, moistening lung clears away heart-fire.For dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, Injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.
Radix Dipsaci, is the dry root of Dipsacaceae plant Radix Dipsaci DipsacusasperWall.exHenry;Bitter in the mouth, pungent, property Tepor;Return liver and kidney channel;Invigorating the liver and kidney, bone and muscle strengthening, continuous injured, only metrorrhagia;For deficiency of the liver and kindey, soreness of the waist and knees, rheumatic arthralgia, fall Flutter damage, injury of tendon and muscle fracture, metrorrhagia, vaginal bleeding during pregnancy.
Fructus Leonuri, this product is the dry mature fruit of labiate Herba Leonuri LeonurusjaponicaHoutt.;Pungent, Hardship, is slightly cold;Thoughts of returning home bag, Liver Channel;Promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.For menoxenia, closed dysmenorrhea, cataract, dizziness is swollen Bitterly.
Semen Cuscutae, this product is convolvulaceous plant Cuscuta australis CuscutaaustralisR.Br. or Semen Cuscutae CuscutachinensisLam. dry mature seed;Acrid in the mouth, sweet, mild-natured;Return liver, kidney, spleen channel;Liver and kidney tonifying, controlling nocturnal emission with astringent drugs contracts Urine, antiabortive, improving eyesight, antidiarrheal;External pathogenic wind expelling speckle dispelling.For deficiency of the liver and kindey, soreness of the waist and knees, impotence and seminal emission, enuresis frequent micturition.Kidney deficiency tire Leakage, frequent fetal movement, blurred vision tinnitus, spleen kidney deficiency is rushed down;Externally treating leucoderma.
Cornu Cervi, is the angle base that spring in next year comes off after animal in deer family Cervus elaphus linnaeuss or the ossified angle of Cervus nippon Temminck or saw young pilose antler, salty in the mouth, Warm in nature;Return kidney, Liver Channel;The kidney warming sun, bone and muscle strengthening, promoting the circulation of blood is subsided a swelling.For insufficiency of kidney-YANG, impotence and seminal emission, spinal column cold type of pain, carbuncle of yin nature skin ulcer Infectionss, acute mastitis is from the beginning of swelling and pain due to blood stasis.Cornu Cervi, Fructus Leonuri and Rhizoma Chuanxiong synergism, enhance promoting the circulation of blood, effect of promoting blood circulation.
Raw material adds starch to play the effect of thickening after making feed liquid, is that next step carries out spray drying and prepares, xylose Alcohol can improve the mouthfeel of the Chinese medicine for the treatment of sterility and infertility so as to preferably drink.
To being divided into twice to the cooking of raw material in preparation method, slow fire after first big fire, not only decreased brew time but also will be former Nutrient substance in material to greatest extent dissolution in feed liquid, concentrated after the feed liquid that obtains add starch and xylitol makes The Chinese medicine that finished product treats sterility and infertility not only has functions that treatment sterility and infertility and building body also have preferable mouthfeel.
Beneficial effects of the present invention are:The Chinese crude drug that the prescription of the present invention is selected all has circulation of qi promoting, promoting blood circulation effect, to women The infertility that qi and blood disorder causes has effect to the ill, and medical material has simultaneously fills out marrow, diuresis, kidney-replenishing, nourishing kidney to male's benefit essence Effect.The present invention adopts the theory of the traditional Chinese medical science, by the conditioning to people's QI and blood, strengthens human body immunity, improves the unit of body Gas, treatment salpingemphraxis, uterine hypoplasia, ovulation failure, inadequate luteal function, endometriosis, hysteromyoma, ovum The infertilities such as nest cyst, make patient be in good interior environment of becoming pregnant, increase the probability become pregnant;By improving exempting from of body Epidemic disease power, the repair ability of enhancing body, the functional statuss of strengthening prostata tissue, especially to fatigue and weakness, soreness of the waist and knees, frequent micturition The sub-health state such as urgent micturition and hypoimmunity has preferable improvement.
Infertile couples both sides take jointly, if disabling immediately after becoming pregnant, treatment sterility and infertility effect substantially, can strengthen people Body immunocompetence, the sterility and infertility especially the subhealth state reason such as uncomfortable being led to has effective.
Specific embodiment
Embodiment 1
A kind of Chinese medicine treating sterility and infertility, is made up of following raw material:Ramulus Cinnamomi 7g, Radix Paeoniae Alba 3g, process Radix Codonopsis 7g, Radix Glycyrrhizae Preparata 0.5g, Fructus Evodiae 3g, Rhizoma Chuanxiong 1g, Radix Angelicae Sinensis 4g, Cortex Moutan 3g, Rhizoma Zingiberis Recenss 7g, Rhizoma Pinelliae Preparatum 3g, 7g Radix Ophiopogonis, Radix Dipsaci 3g, Fructus Leonuri 5g, Tu SIZI 3g, Cornu Cervi 3g.
Preparation method, comprises the following steps:
(1) pre-treatment:By Ramulus Cinnamomi, the Radix Paeoniae Alba, process Radix Codonopsis, Fructus Evodiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Cortex Moutan, Rhizoma Zingiberis Recenss, Rhizoma Pinelliae Preparatum, Radix Ophiopogonis, Radix Dipsaci and Cornu Cervi are pulverized, form length and width, thickness be less than 0.5 centimetre Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block;
(2) mix:By Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss Block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are mixed with Radix Glycyrrhizae Preparata, Fructus Leonuri, Semen Cuscutae, and mix homogeneously is formed Compound;
(3) cook:With 9 times of the weight of compound of water, compound is first soaked 7 hours at 45 DEG C, then carry out cooking 4 Hour, with 65 DEG C of slow fire infusions 1.5 hours after first being decocted 1.5 hours with 90 DEG C of big fire in boiling process, finally again with 78 DEG C Fire carries out concentrating 50 minutes, filters, discard material residue and obtain feed liquid after precipitation;
(4) add adjuvant:Starch and the feed liquid weight 2% of feed liquid weight 6% is added in the feed liquid obtaining in step (3) Xylitol, mix homogeneously makes mixed liquor;
(5) it is spray-dried:Mixed liquor is spray-dried at 78 DEG C, obtaining particle diameter is 500-900 μm of hybrid particles, I.e. finished product.
Embodiment 2
A kind of Chinese medicine treating sterility and infertility, is made up of following raw material:
Ramulus Cinnamomi 3g, Radix Paeoniae Alba 7g, process Radix Codonopsis 3g, Radix Glycyrrhizae Preparata 1.5g, Fructus Evodiae 1g, Rhizoma Chuanxiong 3g, Radix Angelicae Sinensis 2g, Cortex Moutan 5g, Rhizoma Zingiberis Recenss 3g, Rhizoma Pinelliae Preparatum 7g, 3g Radix Ophiopogonis, Radix Dipsaci 5g, Fructus Leonuri 3g, Semen Cuscutae 7g, Cornu Cervi 1g.
Preparation method, comprises the following steps:
(1) pre-treatment:By Ramulus Cinnamomi, the Radix Paeoniae Alba, process Radix Codonopsis, Fructus Evodiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Cortex Moutan, Rhizoma Zingiberis Recenss, Rhizoma Pinelliae Preparatum, Radix Ophiopogonis, Radix Dipsaci and Cornu Cervi are pulverized, form length and width, thickness be less than 0.5 centimetre Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block;
(2) mix:By Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss Block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are mixed with Radix Glycyrrhizae Preparata, Fructus Leonuri, Semen Cuscutae, and mix homogeneously is formed Compound;
(3) cook:With 8 times of the weight of compound of water, compound is first soaked 5 hours at 60 DEG C, then carry out cooking 5 Hour, with 60 DEG C of slow fire infusions 2 hours after first being decocted 2 hours with 85 DEG C of big fire in boiling process, finally entered with 75 DEG C of moderate heats again Row concentrates 40 minutes, filters, discard material residue and obtain feed liquid after precipitation;
(4) add adjuvant:Starch and feed liquid 1% weight of feed liquid 8% weight is added in the feed liquid obtaining in step (3) Xylitol, mix homogeneously makes mixed liquor;
(5) it is spray-dried:Mixed liquor is spray-dried at 80 DEG C, obtaining particle diameter is 500-900 μm of hybrid particles, I.e. finished product.
Embodiment 3
A kind of Chinese medicine treating sterility and infertility, is made up of following raw material:
Ramulus Cinnamomi 5g, Radix Paeoniae Alba 5g, process Radix Codonopsis 5g, Radix Glycyrrhizae Preparata 1g, Fructus Evodiae 2g, Rhizoma Chuanxiong 2g, Radix Angelicae Sinensis 3g, Cortex Moutan 4g, Rhizoma Zingiberis Recenss 5g, Rhizoma Pinelliae Preparatum 5g, 5g Radix Ophiopogonis, Radix Dipsaci 4g, Fructus Leonuri 4g, Semen Cuscutae 5g, Cornu Cervi 2g.
Preparation method, comprises the following steps:
(1) pre-treatment:By Ramulus Cinnamomi, the Radix Paeoniae Alba, process Radix Codonopsis, Fructus Evodiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Cortex Moutan, Rhizoma Zingiberis Recenss, Rhizoma Pinelliae Preparatum, Radix Ophiopogonis, Radix Dipsaci and Cornu Cervi are pulverized, form length and width, thickness be less than 0.5 centimetre Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block;
(2) mix:By Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss Block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are mixed with Radix Glycyrrhizae Preparata, Fructus Leonuri, Semen Cuscutae, and mix homogeneously is formed Compound;
(3) cook:With 10 times of the weight of compound of water, compound is first soaked 8 hours at 35 DEG C, then carry out cooking 2 Hour, with 70 DEG C of slow fire infusions 1 hour after first being decocted 1 hour with 93 DEG C of big fire in boiling process, finally entered with 80 DEG C of moderate heats again Row concentrates 60 minutes, filters, discard material residue and obtain feed liquid after precipitation;
(4) add adjuvant:Starch and feed liquid 3% weight of feed liquid 5% weight is added in the feed liquid obtaining in step (3) Xylitol, mix homogeneously makes mixed liquor;
(5) it is spray-dried:Mixed liquor is spray-dried at 65 DEG C, obtaining particle diameter is 500-900 μm of hybrid particles, I.e. finished product.
Above-described embodiment formula is the result through test of many times research for the inventor, can play preferable treatment through on probation The effect of sterility and infertility and the effect of enhancing human body immunity power.Taking Clinical practice 50 as a example, female acyesis person 30 people, takes reality Apply the Chinese medicine of the treatment sterility and infertility that example 1 obtains, after patient takes, recover normal ovulation function;Male sterility person 20 people, Take the Chinese medicine of the treatment sterility and infertility that embodiment 3 obtains, after patient takes, spermatogenesis effect is preferable, and nontoxic pair of effect;With In upper 50, total cure rate (having become pregnant and raw son) is 92%, effective percentage (ovulation is normal or sperm quality has been lifted) 96%, no activity ratio 4%.
Concrete case:
Case 1
Zhao, female, 32 years old, two tires, when examining, ovarian cyst, take the embodiment of the present invention 1 be obtained Chinese medicine, 26 days Afterwards, pregnancy, gives birth to a girl afterwards.
Case 2
Pungent certain, female, 28 years old, the unpregnancy for many years of marrying, take the Chinese medicine that the embodiment of the present invention 1 is obtained, after 82 days, pregnancy, after A raw girl.
Case 3
Zhang, man, 38 years old, few smart and premature ejaculation, take the Chinese medicine that the embodiment of the present invention 3 is obtained, after 15 days, semen volume is earlier above Increasing by 25%, sperm concentration all increases by 50% earlier above.
The present invention is not limited to above-mentioned preferred forms, and anyone can show that under the enlightenment of the present invention other are various The product of form, however, making any change in its shape or structure, every have skill identical or similar to the present application Art scheme, is within the scope of the present invention.

Claims (9)

1. a kind of Chinese medicine treating sterility and infertility it is characterised in that:Raw material including following weight portion:Ramulus Cinnamomi 3-7 part, Radix Paeoniae Alba 3- 7 parts, process Radix Codonopsis 3-7 part, Radix Glycyrrhizae Preparata 0.5-1.5 part, Fructus Evodiae 1-3 part, Rhizoma Chuanxiong 1-3 part, Radix Angelicae Sinensis 2-4 part, Cortex Moutan 3-5 part, life Rhizoma Zingiberis Recens 3-7 part, Rhizoma Pinelliae Preparatum 3-7 part, 3-7 part Radix Ophiopogonis, Radix Dipsaci 3-5 part, Fructus Leonuri 3-5 part, Semen Cuscutae 3-7 part, Cornu Cervi 1-3 part.
2. according to claim 1 treatment sterility and infertility Chinese medicine it is characterised in that:Raw material including following weight portion: 5 parts of Ramulus Cinnamomi, 5 parts of the Radix Paeoniae Alba, process 5 parts of Radix Codonopsis, 1 part of Radix Glycyrrhizae Preparata, 2 parts of Fructus Evodiae, 2 parts of Rhizoma Chuanxiong, 3 parts of Radix Angelicae Sinensis, 4 parts of Cortex Moutan, Rhizoma Zingiberis Recenss 5 Part, 5 parts of Rhizoma Pinelliae Preparatum, 5 parts of Radix Ophiopogonis, 4 parts of Radix Dipsaci, 4 parts of Fructus Leonuri, 5 parts of Semen Cuscutae, 2 parts of Cornu Cervi.
3. a kind of as claimed in claim 1 or 2 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Including with Lower step:
(1) pre-treatment:By Ramulus Cinnamomi, the Radix Paeoniae Alba, process Radix Codonopsis, Fructus Evodiae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Cortex Moutan, Rhizoma Zingiberis Recenss, Rhizoma Pinelliae Preparatum, Radix Ophiopogonis, Radix Dipsaci Pulverize with Cornu Cervi, form Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, method Rhizoma Pinelliae block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block;
(2) mix:By described Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss Block, Rhizoma Pinelliae Preparatum block, block Radix Ophiopogonis, Radix Dipsaci block and Cornu Cervi block are mixed with Radix Glycyrrhizae Preparata, Fructus Leonuri, Semen Cuscutae, and mix homogeneously is formed Compound;
(3) cook:With 8-10 times of the weight of described compound of water, described compound is first soaked, then carry out cooking 2- 5 hours, first use slow fire infusion with after big fire decoction in boiling process, finally concentrated with moderate heat again, filter after precipitation, discard Material residue obtains feed liquid;
(4) add adjuvant:The starch of described feed liquid 5-8% weight and described is added in the described feed liquid obtaining in step (3) The xylitol of feed liquid 1-3% weight, mix homogeneously makes mixed liquor;
(5) it is spray-dried:Mixed liquor is spray-dried, is obtained hybrid particles, i.e. finished product.
4. according to claim 3 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Institute in step (1) State Ramulus Cinnamomi block, Radix Paeoniae Alba block, process Radix Codonopsis block, Fructus Evodiae block, Rhizoma Chuanxiong block, Radix Angelicae Sinensis block, Cortex Moutan block, Rhizoma Zingiberis Recenss block, Rhizoma Pinelliae Preparatum block, Radix Ophiopogonis Block, Radix Dipsaci block and Cornu Cervi block are length and width, the thick square being less than 0.5 centimetre.
5. according to claim 3 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Institute in step (3) Stating immersion is immersion 5-8 hour at 35-60 DEG C.
6. according to claim 3 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Institute in step (3) The temperature stating big fire is 85-93 DEG C, and the time of described decoction is 1-2 hour;The temperature of described slow fire is 60-70 DEG C, described endures The time boiled is 1-2 hour;The temperature of described moderate heat is 75-80 DEG C, and the time of described concentration is 40-60 minute.
7. according to claim 6 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Institute in step (3) The brew time stated is 3 hours, and the time of wherein said decoction is 1.5 hours, and the time of described infusion is 1.5 hours;Described The time concentrating is 50 minutes.
8. according to claim 3 treatment sterility and infertility Chinese medicine preparation method it is characterised in that:Institute in step (4) The addition stating starch is the 6% of described feed liquid weight, and the addition of described xylitol is the 2% of described feed liquid weight.
9. a kind of Chinese medicine treating sterility and infertility according to claim 3 preparation method it is characterised in that:Step (5) Described in the temperature that is spray-dried be 65-80 DEG C, the particle diameter of described hybrid particles is 500-900 μm.
CN201610854501.5A 2016-09-27 2016-09-27 Traditional Chinese medicine for treating infertility and preparation method thereof Pending CN106377741A (en)

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Application publication date: 20170208