CN106361903A - Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat - Google Patents
Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat Download PDFInfo
- Publication number
- CN106361903A CN106361903A CN201610995274.8A CN201610995274A CN106361903A CN 106361903 A CN106361903 A CN 106361903A CN 201610995274 A CN201610995274 A CN 201610995274A CN 106361903 A CN106361903 A CN 106361903A
- Authority
- CN
- China
- Prior art keywords
- preparation
- chinese medicine
- liquid
- medicine composition
- herb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a preparation method of a traditional Chinese medicine composition capable of relieving swollen sore throat. The preparation method comprises the following steps of (1) weighing folium sauropi, radix aconiti carmichaeli, flos osmanthi fragrantis, folium eriobotryae, fiveleaf gynostemma herb, purple flower holly leaf, goldenrod herb, creeping woodsorrel herb, folium viticis negundo, and poria cocos in parts by weight; (2) soaking the weighed raw materials of traditional Chinese medicine, and adding water to decoct; (3) after decocting, filtering, heating and concentrating filtering liquid to form a gel-shaped matter, adding ethanol to stir, and refrigerating the stirred liquid at low temperature; (4) filtering the refrigerated liquid, and recycling the ethanol by a distilling method; (5) adding a food preservative into the distilled liquid, packaging into a finished product, and sterilizing and disinfecting by a pasteurization method, so as to obtain oral liquid. The preparation method has the advantages that the active ingredients in the raw materials of traditional Chinese medicine are effectively utilized, and the content of effective ingredients in the oral liquid is increased by the high-efficiency concentration and extraction.
Description
Technical field
The present invention relates to tcm field, specifically refer to a kind of preparation method of the Chinese medicine composition alleviating laryngopharynx swelling and pain.
Background technology
Upper respiratory tract infection has 70%～80% to be caused by virus.Including rhinovirus, coronavirus, adenoviruss, influenza and pair
Influenza virus, respiratory syncytial virus, echovirus, Coxsackie viruss etc..The upper sense separately having 20%～30% is caused by antibacterial.Carefully
Bacterium infection can direct infection or after being secondary to virus infection, secondly be most common with Hemolytic streptococcuss, be the bloodthirsty bar of influenza
Bacterium, streptococcus pneumoniae, staphylococcuses etc., occasionally for gram-negative bacteria.Various lead to whole body or respiratory tract local defense function fall
Low the reason, such as suffer from cold, drench with rain, abrupt change of climate, fatigue etc. can make former being present in upper respiratory tract or invade from extraneous
Virus or antibacterial breed rapidly, thus inducing primary disease.Old germling is weak, immunologic hypofunction or with chronic respiratory tract disease
Patient susceptible.Treatment upper respiratory tract infection should distinguish inflammatory type, using Western medicine, Chinese medicine all can, and Chinese medicine be used for treatment
Respiratory tract infection medicine, due to having Small side effects, eutherapeutic feature, therefore is favored by people very much.
Content of the invention
It is an object of the invention to provide a kind of can fundamentally effectively alleviate in respiratory tract laryngopharynx swelling and pain from inside to outside
The preparation method of drug composition.
The present invention is achieved through the following technical solutions: a kind of system of the preparation method of Chinese medicine composition alleviating laryngopharynx swelling and pain
Preparation Method, comprises the following steps:
(1) represented with weight portion, weigh imperial leaf 7-13 part, Radix Aconiti Lateralis Preparata 2-6 part, Flos Osmanthi Fragrantis 5-9 part, Folium Eriobotryae 4-11 part first, twist
The blue 6-12 part of stock, Ilex purpurea Hassk.[I.chinensis Sims 3-8 part, Herba Solidaginiss 3-11 part, Herba Oxalidis Corniculatae 4-9 part, Folium Viticis Negundo 6-12 part, Poria 4-13 part；
(2) Chinese herb weighing is soaked 20-25 minute, then start to add water to cook；
(3) carry out being filtrated to get filtrate after decocting, then carry out heating the glue concentrating formation relative density for 0.8-1.1 by filtrate
Shape thing, 92% ethanol being subsequently adding 2-4 times amount is sufficiently stirred for, and the liquid after stirring is carried out the low temperature cold of 30 hours
Hide；
(4) solution after cold preservation is filtered precipitate, then ethanol is reclaimed by the way of distillation；
(5) add food preservative in the liquid after distillation, finally encapsulation finished product sterilization is carried out using pasteurization disappear
Poison, obtains final product oral administration solution.
Further, soak in described step (2) and concretely comprising the following steps of decocting:
A, first the Chinese herb after weighing is cleaned up, after cleaning put into Chinese herb in clear water or pure water and soak
20 ~ 25 minutes, soaking institute's water requirement was 2 ~ 3l；
B then by soak after Chinese herb and its soak transfer to together in medicine decocting tank, add a cover and decocted；
When c, decoction, before not boiling with high heat first, after the solution boiling in medicine decocting tank, lid is taken off, and use slow fire instead and decoct again
Endure 30 ~ 60 minutes, need to stir 5 ~ 6 times during entirely boiling medicine；
D, second decoct need to add water not Chinese herb 2 ~ 5cm, then or first boil with high heat, then with boiling by slow fire
15 ~ 23 minutes.
Further, in described step (3), deepfreeze is that liquid after adding ethanol is transferred in freezer, 274 ~
Low-temperature precipitation 30 hours at a temperature of 276k.
Further, in described step (3), concentration process uses vacuum decompressioning and concentrating tank.
Further, described step (5) has been also added with aspartame and sucrose, and he is mould in order to receive for described food additive preservative
Element.
A kind of crude drug pharmacology of Chinese medicine composition for treating hypertrophic gastritis of the present invention:
Long Ye: mild-natured, sweet in the mouth, light.Return lung warp, stomach.Nourishing the lung to arrest cough, relieving constipation.Under genus expectorants, antitussives and anti-asthmatics medicine, classification stops
Cough anti-asthmatic.
Radix Aconiti Lateralis Preparata: warm in nature, acrid in the mouth.Poisonous.Return stomach, Liver Channel.Wind-dispelling expectorant, arresting convulsion jerk, detoxify, eliminating stagnation, pain relieving.Belong to resolving sputum to stop
Cough the medicine for warming and resolving cold-phlegm of anti-asthmatic subordinate classification.
Flos Osmanthi Fragrantis: warm in nature, acrid in the mouth.Return lung warp, spleen channel, kidney channel.Warming the lung to resolve fluid-retention, dispersing cold for relieving pain.Belong under expectorants, antitussives and anti-asthmatics medicine
Belong to the medicine for warming and resolving cold-phlegm of classification.
Folium Eriobotryae: bitter in the mouth, cold nature.Return lung warp, stomach.Clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Belong to expectorants, antitussives and anti-asthmatics medicine subordinate
In medicine for the treatment of cough and asthma.
Herb Gynostemmae Pentaphylli: cold in nature, bitter in the mouth.Return lung warp, spleen channel, kidney channel.Heat-clearing and toxic substances removing, eliminating phlegm and stopping cough, and have the strong of similar Radix Ginseng
Strong benefiting action.Belong to the Qi-tonifying drug of classification under qi-restoratives medicine.
Ilex purpurea Hassk.[I.chinensis Sims: cool in nature, bitter in the mouth, puckery.Return lung warp, large intestine channel, bladder warp.Heat-clearing and toxic substances removing, subsiding swelling and resolving stagnation.Belong under antipyretic
Belong to the heat and toxic materials clearing away medicine of classification.
Herba Solidaginiss: cool in nature, acrid in the mouth, hardship.Return lung warp, Liver Channel.Dispelling wind, heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Belong to diaphoretic medicine subordinate
The pungent and cold medicine for relieving the exterior syndrome of classification.
Herba Oxalidis Corniculatae: cold in nature, sour in the mouth.Return liver warp, lung meridian, bladder warp.Clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis, removing toxic substances and promoting subsidence of swelling.Belong to heat clearing away
The heat clearing and dampness removing medicine of medicine subordinate classification.
Folium Viticis Negundo: mild-natured, mildly bitter flavor, pungent.Return lung warp.Induce sweat, eliminating the phlegm, cough-relieving, relieving asthma.Belong to expectorants, antitussives and anti-asthmatics medicine subordinate
The medicine for the treatment of cough and asthma of classification.
Poria: mild-natured, sweet in the mouth, light.Thoughts of returning home warp, lung meridian, spleen channel, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Belong to promoting diuresis to eliminate damp pathogen
The edema-alleviating diuretic of medicine subordinate classification.
The present invention compared with prior art, has advantages below and a beneficial effect:
The present invention, by the symptom of the respiratory tract disease that studies for a long period of time and the cause of disease, then fundamentally goes to solve using Chinese medicine formula
The problem of respiratory inflammation, compared to Western medicine, Chinese medicine formula can not only be alleviated the cough that inflammation brings, laryngopharynx swelling and pain, swallow
The symptoms such as pain, and can solve the problem that old complaint, prevent disease recurrent exerbation；Compared with existing Chinese medicine formula, inventive formulation
Constitute clearly, the effect of preparation is substantially it is adaptable to the upper respiratory disease that causes of Different types of etiopathogenises.And the preparation method energy invented
Enough action components effectively utilizing Chinese herb, by efficiently concentrating and extracting, to improve the effective one-tenth in oral liquid
Divide content；Then effect of extracting can be improved further by low-temperature precipitation technique.
Specific embodiment
Embodiments of the invention are described below in detail.
Embodiment 1:
A kind of Chinese medicine composition of alleviation laryngopharynx swelling and pain of the present embodiment, described pharmaceutical compositions include imperial leaf 7-13
Part, Radix Aconiti Lateralis Preparata 2-6 part, Flos Osmanthi Fragrantis 5-9 part, Folium Eriobotryae 4-11 part, Herb Gynostemmae Pentaphylli 6-12 part, Ilex purpurea Hassk.[I.chinensis Sims 3-8 part, Herba Solidaginiss 3-11 part,
Herba Oxalidis Corniculatae 4-9 part, Folium Viticis Negundo 6-12 part, Poria 4-13 part.
The preparation method of medicine of the present invention, comprises the following steps:
(1) represented with weight portion, weigh imperial leaf 7-13 part, Radix Aconiti Lateralis Preparata 2-6 part, Flos Osmanthi Fragrantis 5-9 part, Folium Eriobotryae 4-11 part first, twist
The blue 6-12 part of stock, Ilex purpurea Hassk.[I.chinensis Sims 3-8 part, Herba Solidaginiss 3-11 part, Herba Oxalidis Corniculatae 4-9 part, Folium Viticis Negundo 6-12 part, Poria 4-13 part；
(2) Chinese herb weighing is soaked 20-25 minute, then start to add water to cook；
(3) carry out being filtrated to get filtrate after decocting, then carry out heating the glue concentrating formation relative density for 0.8-1.1 by filtrate
Shape thing, 92% ethanol being subsequently adding 2-4 times amount is sufficiently stirred for, and the liquid after stirring is carried out the low temperature cold of 30 hours
Hide；
(4) solution after cold preservation is filtered precipitate, then ethanol is reclaimed by the way of distillation；
(5) add food preservative in the liquid after distillation, finally encapsulation finished product sterilization is carried out using pasteurization disappear
Poison, obtains final product oral administration solution.
Embodiment 2:
A kind of Chinese medicine composition alleviating laryngopharynx swelling and pain of the present embodiment, is represented with weight portion, described 9 parts of leaf of dragon, 3 parts of Radix Aconiti Lateralis Preparata,
8 parts of Flos Osmanthi Fragrantis, 10 parts of Folium Eriobotryae, 6 parts of Herb Gynostemmae Pentaphylli, 4 parts of Ilex purpurea Hassk.[I.chinensis Sims, 5 parts of Herba Solidaginiss, 4 parts of Herba Oxalidis Corniculatae, 7 parts of Folium Viticis Negundo, Poria 6
Part.
Embodiment 3:
A kind of Chinese medicine composition alleviating laryngopharynx swelling and pain of the present embodiment, is represented with weight portion, described 8 parts of leaf of dragon, 6 parts of Radix Aconiti Lateralis Preparata,
6 parts of Flos Osmanthi Fragrantis, 9 parts of Folium Eriobotryae, 11 parts of Herb Gynostemmae Pentaphylli, 7 parts of Ilex purpurea Hassk.[I.chinensis Sims, 9 parts of Herba Solidaginiss, 8 parts of Herba Oxalidis Corniculatae, 11 parts of Folium Viticis Negundo, Poria 5
Part.
Embodiment 4:
A kind of Chinese medicine composition alleviating laryngopharynx swelling and pain of the present embodiment, is represented with weight portion, described 12 parts of leaf of dragon, 5 parts of Radix Aconiti Lateralis Preparata,
8 parts of Flos Osmanthi Fragrantis, 5 parts of Folium Eriobotryae, 8 parts of Herb Gynostemmae Pentaphylli, 8 parts of Ilex purpurea Hassk.[I.chinensis Sims, 6 parts of Herba Solidaginiss, 5 parts of Herba Oxalidis Corniculatae, 9 parts of Folium Viticis Negundo, Poria 11
Part.
Using medicine of the present invention be directed to various upper respiratory tract infection patients clinical statisticses data:
Through the Clinical practice of 250 patients, wherein male patient 137, female patient 113, medication age object 15 ~ 45 years old.Its
Middle minimum 17 years old, maximum 45 years old, 23 years old mean age；Mild upper respiratory inflammation case 103, moderate upper-respiratory inflammation disease
Example 84, severe upper respiratory tract infection case 63.
Wherein mild upper respiratory infection patient's symptom is: patient feels pharyngeal sense of discomfort, and feels that throat is dry and itch,
Discontinuity cough occurs, often more frequent with early morning cough at dusk；
Moderate upper-respiratory infection patient's symptom be: patient often have pharyngalgia, shed tears, the disease such as hypogeusia, hypopnea, hoarseness
Shape, and it is also accompanied by cough, dry pharynx, itching throat or burning sensation, there are water clock sense, headache, heating, fear of cold after nose, or even fever occurs
Symptom；
Severe upper respiratory tract infection patient's symptom is: patient has sore throat unbearably, swallows liquid or saliva also occurs play
Strong pain, and the situation of dysphagia occurs；And cough constantly, and sputum mixed with blood, fever, general weakness, nose, pharynx, larynx are bright
Aobvious congested, edema, submandibular lymph nodes enlargement, tenderness.
Model case:
1st, Wang, female, 22 years old, cough in the obvious inducement of January Yu Qianwu, is that monophone is coughed, no expectorant, with low grade fever, body temperature highest
37.8 DEG C, with fear of cold, abdominal distention, acid regurgitation, stomach poor appetite, no with diarrhoea stomachache, go to a doctor to hospital outpatient, diagnose " upper respiratory tract sense
Dye ", gives western medicine, remission.Traveled with household before 3 weeks, period occurs generating heat again, and up to 42 DEG C of body temperature, with fear
Cold, shiver with cold, and vomit once, it is gastric content, with cough and expectoration, be that monophone is coughed, expectorant is few, be yellow purulent sputum, outpatient service is given and being brought down a fever
Deng treatment after still repeatedly generate heat；And treated using the Chinese medicine formula in the present invention, after three courses for the treatment of, body low grade fever symptom disappears
Move back, the symptom such as fear of cold, abdominal distention has been alleviated, and cough symptom is clearly better；After five courses for the treatment of, cough symptom substantially to disappear,
Appetite is recovered, and sleep quality improves.
2nd, Lee, man, 31 years old, overtime work of often staying up late at ordinary times, the daily schedule is irregular, and before 2 years, no substantially inducement occurs
Dry pharynx, cough, cough is in ictal, each last for several minutes, and compared with daytime frequently, impact sleep, with white on a small quantity for night-time attack
Frothy sputum, no heating, shiver with cold, night sweat, no spitting of blood, chest pain, breathing are tired, repeatedly go to a doctor in local hospital, give anti-infective therapy
(specifically unknown) take " Radix Glycyrrhizae tabellae, ketotifen, clarityne, Bricanyl " etc. and all can not alleviate.Near hear over the past half year and oil smoke,
Coating has coughing fit, and nocturnal cough gradually increases, and in persistence it is impossible to prostration, need to take seat, with chest pain, asthma
Occur etc. symptom, and treated using the Chinese medicine formula of the present invention, the symptom such as dry pharynx cough is clearly better, and no longer occurs continuing
Property cough symptom, and night chest pain and dyspneic symptom also gradually disappear, the mental status takes an evident turn for the better.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not
Multiple changes, modification, replacement and modification can be carried out to these embodiments under the principle of the disengaging present invention and objective, the present invention's
Scope is limited by claim and its equivalent.
Claims (5)
1. a kind of preparation method of the Chinese medicine composition alleviating laryngopharynx swelling and pain, it is characterized by being, comprises the following steps:
(1) represented with weight portion, weigh imperial leaf 7-13 part, Radix Aconiti Lateralis Preparata 2-6 part, Flos Osmanthi Fragrantis 5-9 part, Folium Eriobotryae 4-11 part first, twist
The blue 6-12 part of stock, Ilex purpurea Hassk.[I.chinensis Sims 3-8 part, Herba Solidaginiss 3-11 part, Herba Oxalidis Corniculatae 4-9 part, Folium Viticis Negundo 6-12 part, Poria 4-13 part；
(2) Chinese herb weighing is soaked 20-25 minute, then start to add water to cook；
(3) carry out being filtrated to get filtrate after decocting, then carry out heating the glue concentrating formation relative density for 0.8-1.1 by filtrate
Shape thing, 92% ethanol being subsequently adding 2-4 times amount is sufficiently stirred for, and the liquid after stirring is carried out the low temperature cold of 30 hours
Hide；
(4) solution after cold preservation is filtered precipitate, then ethanol is reclaimed by the way of distillation；
(5) add food preservative in the liquid after distillation, finally encapsulation finished product sterilization is carried out using pasteurization disappear
Poison, obtains final product oral administration solution.
2. the preparation method of a kind of Chinese medicine composition alleviating laryngopharynx swelling and pain according to claim 1, it is characterized by being,
That soaks in described step (2) and decoct concretely comprises the following steps:
A, first the Chinese herb after weighing is cleaned up, after cleaning put into Chinese herb in clear water or pure water and soak
20 ~ 25 minutes, soaking institute's water requirement was 2 ~ 3l；
B then by soak after Chinese herb and its soak transfer to together in medicine decocting tank, add a cover and decocted；
When c, decoction, before not boiling with high heat first, after the solution boiling in medicine decocting tank, lid is taken off, and use slow fire instead and decoct again
Endure 30 ~ 60 minutes, need to stir 5 ~ 6 times during entirely boiling medicine；
D, second decoct need to add water not Chinese herb 2 ~ 5cm, then or first boil with high heat, then with boiling by slow fire
15 ~ 23 minutes.
3. the preparation method of a kind of Chinese medicine composition alleviating laryngopharynx swelling and pain according to claim 1 and 2, its feature exists
In: in described step (3), deepfreeze is the liquid after ethanol will to be added to transfer in freezer, low temperature at a temperature of 274 ~ 276k
Precipitation 30 hours.
4. the preparation method of a kind of Chinese medicine composition alleviating laryngopharynx swelling and pain according to claim 1 and 2, its feature exists
In: in described step (3), concentration process uses vacuum decompressioning and concentrating tank.
5. the preparation method of a kind of Chinese medicine composition alleviating laryngopharynx swelling and pain according to claim 1 and 2, its feature exists
In: described step (5) has been also added with aspartame and sucrose, and described food additive preservative is natamycin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610995274.8A CN106361903A (en) | 2016-11-11 | 2016-11-11 | Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610995274.8A CN106361903A (en) | 2016-11-11 | 2016-11-11 | Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106361903A true CN106361903A (en) | 2017-02-01 |
Family
ID=57893363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610995274.8A Withdrawn CN106361903A (en) | 2016-11-11 | 2016-11-11 | Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106361903A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142430A (en) * | 2021-03-25 | 2021-07-23 | 大洲新燕(厦门)生物科技有限公司 | Sodium hyaluronate composite beverage and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147151A (en) * | 2014-08-06 | 2014-11-19 | 韦振良 | Traditional Chinese medicinal composition for treating sore throat and preparation method thereof |
| CN105641534A (en) * | 2016-03-30 | 2016-06-08 | 滕钜海 | Chinese herbal medicine composition for treating sore throat and its preparation and preparation method |
-
2016
- 2016-11-11 CN CN201610995274.8A patent/CN106361903A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147151A (en) * | 2014-08-06 | 2014-11-19 | 韦振良 | Traditional Chinese medicinal composition for treating sore throat and preparation method thereof |
| CN105641534A (en) * | 2016-03-30 | 2016-06-08 | 滕钜海 | Chinese herbal medicine composition for treating sore throat and its preparation and preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142430A (en) * | 2021-03-25 | 2021-07-23 | 大洲新燕(厦门)生物科技有限公司 | Sodium hyaluronate composite beverage and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101273778A (en) | Honeysuckle cold tea and method for preparing the same | |
| CN107372943B (en) | Health tea for promoting digestion and preventing halitosis as well as preparation method and application thereof | |
| CN103816253A (en) | Traditional Chinese medicine prescription for treating chronic gastritis and gastric ulcer | |
| CN103798476A (en) | Health-care tea and preparation method thereof | |
| CN104096076A (en) | Traditional Chinese medicine composition for treating ozostomia | |
| CN105079445A (en) | Traditional Chinese medicine composition for treating pharyngitis | |
| CN111701006A (en) | Preparation method of plant water extract for preventing and treating cold | |
| CN106361903A (en) | Preparation method of traditional Chinese medicine composition capable of relieving swollen sore throat | |
| CN105079464A (en) | Traditional Chinese medicine for treating sore throat | |
| CN104547048A (en) | Chinese herbal medicine compound preparation for preventing and treating infantile hand-foot-mouth disease and preparation method thereof | |
| CN105106565A (en) | Traditional Chinese medicine composition capable of clearing heat, relieving sore throat and detoxifying | |
| CN101584827A (en) | Traditional Chinese medicine for treating cold in children | |
| CN104721669A (en) | Decoction medicine for treating pertussis encephalopathy and preparation method thereof | |
| CN103893488A (en) | Chinese medicine preparation for treating migraine and preparation method thereof | |
| CN106389570A (en) | Preparation method of traditional Chinese medicine composition for treating upper respiratory inflammation | |
| CN106344721A (en) | Traditional Chinese medicine composition for relieving swollen sore throat | |
| CN103893657B (en) | A kind of Traditional Chinese medicine lozenge and preparation method for the treatment of halitosis | |
| CN105617321A (en) | Decoction medicine for treating phlegm heat cough and preparation method thereof | |
| CN102688354B (en) | Traditional Chinese medicine decoction of schizonepeta for treating cough and preparation method thereof | |
| CN107361186A (en) | A kind of sunstroke prevention tea | |
| CN106389569A (en) | Traditional Chinese medicine composition for treating upper respiratory inflammation | |
| CN105106564A (en) | Traditional Chinese medicine composition for treating swollen sore throat | |
| CN106389915A (en) | Preparation method of traditional Chinese medicine composition for treating bronchitis | |
| CN113262289A (en) | Traditional Chinese medicine composition and preparation for treating nasal sinusitis and preparation method thereof | |
| CN117899162A (en) | Traditional Chinese medicine composition and preparation for treating chronic pharyngitis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170201 |
|
| WW01 | Invention patent application withdrawn after publication |