CN106361381B - Left ventricle capacity-reduction device - Google Patents
Left ventricle capacity-reduction device Download PDFInfo
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- CN106361381B CN106361381B CN201510431437.5A CN201510431437A CN106361381B CN 106361381 B CN106361381 B CN 106361381B CN 201510431437 A CN201510431437 A CN 201510431437A CN 106361381 B CN106361381 B CN 106361381B
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- main body
- left ventricle
- reduction device
- outer layer
- internal layer
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- 210000005240 left ventricle Anatomy 0.000 title claims abstract description 131
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- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 claims abstract description 20
- 229910001000 nickel titanium Inorganic materials 0.000 claims abstract description 20
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 claims abstract description 14
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- 238000004064 recycling Methods 0.000 description 6
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- 238000002955 isolation Methods 0.000 description 4
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- 238000004873 anchoring Methods 0.000 description 3
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12122—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
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- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12177—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
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- A—HUMAN NECESSITIES
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- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
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- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00597—Implements comprising a membrane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00632—Occluding a cavity, i.e. closing a blind opening
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
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- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
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Abstract
The invention discloses a kind of left ventricle capacity-reduction devices, comprising: main body and pedestal, the main body include main body outer layer and main body internal layer, and the main body outer layer is cut by laser using Nitinol pipe, are heat-treated, are polished to cup-shaped；The lower end of the main body outer layer is the structure of closed loop, be conducive to release expansion, the upper end of the main body outer layer is several support rods, the end of the support rod is equipped with a hole, for connecting the main body internal layer, and the main body internal layer is woven using titanium-nickel wire, titanium-nickel wire used passes through the hole and is attached, collect after the both ends of titanium-nickel wire are woven in the bottom of the main body internal layer, and one steel bushing is set in the bottom of the main body internal layer, the steel bushing is used to connect the bolt head of conveying lever, grid below the main body outer layer pools tubular structure, the tubular structure is connect with the pedestal.The present invention be it is a kind of it is repeatable positioning, fixing-stable left ventricle capacity-reduction device.
Description
Technical field
The present invention relates to left ventricle volume reduction technical field more particularly to the left ventricles of a kind of repeatable positioning, fixing-stable
Capacity-reduction device.
Background technique
Heart failure be it is a kind of it is common make one weak, and be possible to lethal disease, the heart of patient can not provide foot
Enough blood flow meets the needs of body.The symptom of heart failure has negative effect to quality of life, including short of breath, lasting
It coughs or wheezes, excessive hydrops (oedema), tired, appetite stimulator or nausea, thought slowness, increased heart rate in body tissue.Closely
The illness rate of heart failure increases year by year over year, becomes serious public health problem, it was reported that there are 17,000,000 people in the annual whole world
Cardiovascular disease is died of, wherein more than half dies of acute myocardial infarction AMI, and it is the chronic heart that development is easy after patient's survival
Force failure.The disease incidence of Chinese acute myocardial infarction AMI is about 450,000~550,000 according to estimates, still in rising trend at present, heart failure
Illness rate is 0.9%, in the cause of disease coronary heart disease by 1980 36.8% rise to 2000 45.6%, occupy the various causes of disease it
It is first.About 20%~50% patient can develop as heart failure, especially Anterior wall myocardial infarction, the heart after acute myocardial infarction AMI
Force failure is various cardiopathic severe stages, and disease incidence is high, and 5 annual survival rates and malignant tumour are similar.
After myocardial infarction, the left room cardiac muscle in part necroses, and cardiac enlargement then occurs, cardiac pumping function reduces, the heart
Output quantity is reduced, and leads to the heart failure symptoms such as expiratory dyspnea.Currently, U.S. ischemic heart failure patient is there are about 1,500,000,
Newly-increased patient about 120,000 every year.For ischemic heart failure, although drug therapy can be used by clinician and heart is same again
The mechanotherapies such as step treatment (CRT), but since the cause of disease fails to be corrected, the state of an illness of most of patient can not still be alleviated, even
May deteriorate, more after it is also not satisfactory.
Studies have shown that there is left ventricle dilation in many patients, and heart stroke is caused to reduce, and then cause after heart attack
It the heart failure symptoms such as is short of breath.Left ventricle capacity-reduction device instrument is one for the catheter-based micro- of damaged myocardium to be isolated
Treatment technology is created, non-functional cardiac component and health, functional part are kept apart, to reduce the total of left ventricle
Volume restores its form and function.The technology is carried out under conditions of limited calm in conduit loading test room.Clinical data
It has been shown that, after patient receives left ventricle capacity-reduction device mechanotherapy, there is overall improve in heart function and quality of life.
So far, unique left ventricle capacity-reduction device has the Cardiokinetix company in the U.S. to invent Parachute in the world
Left ventricle capacity-reduction device, such as patent of invention US7887477B2, US2014/0179993 A1, US2014/0296624 A1 and
Described in US2014/0343356 A1, which is related to an inverted umbrella-shaped structure, is covered by expanded PTFE (ePTFE)
Film is fixed on NiTi (NiTi) shape memory metal skeleton of an expansion.There is a petal plastic bottom in base portion
Seat.The left ventricle capacity-reduction device of suitable size is selected according to Preoperative ultrasound kinetocardiography when placing.First by scabbard
Along arteries channel, through femoral artery, aorta, scabbard is put into left ventricle apex of the heart position by aorta petal.Then in body
After assembling outside with conveying lever, left ventricle capacity-reduction device is pushed into left ventricle apex along scabbard.Fixed conveying lever, is returned
Scabbard is removed in the pedestal of left ventricle apex of the heart position release left ventricle capacity-reduction device, continues to withdraw scabbard until left ventricle
Capacity-reduction device goes out long sheath.The sacculus for expanding conveying lever distal end, makes expanded PTFE overlay film passively be anchored on endocardium
On.Or aneurysm uncoordinated for ventricular wall motion after myocardial infarction forms patient, and the ventricular chamber where isolation inactivation cardiac muscle can change
Kind left ventricle geometric configuration reduces left ventricular volume, prevents Heart enlargement, reduces wall tension, so as to prevent left ventricle into
One step reconstructs.If but the position that the instrument is once placed is bad, can not recycle and carry out repeating adjustment.Cause to doctor
Operation require relatively high, prevent the position that instrument is placed is from reaching optimum position, and success rate of operation is lower.
Therefore, a kind of recyclable, the left ventricle capacity-reduction device of repeatable positioning is needed.
Summary of the invention
It is recyclable that the object of the present invention is to provide one kind, repeats the left ventricle capacity-reduction device of positioning.
To achieve the goals above, technical solution provided by the invention are as follows: a kind of left ventricle capacity-reduction device is provided, comprising:
Main body and pedestal, the main body include main body outer layer and main body internal layer, and the main body outer layer is cut using Nitinol pipe through laser
It cuts, is heat-treated, is polished to cup-shaped；The lower end of the main body outer layer is the structure of closed loop, is conducive to release and is unfolded, outside the main body
The upper end of layer is several support rods, and the end of the support rod is equipped with a hole, for connecting the main body internal layer, and the main body
Internal layer is woven using titanium-nickel wire, and titanium-nickel wire used passes through the hole and is attached, in institute after the both ends of titanium-nickel wire are woven
The bottom for stating main body internal layer is collected, and a steel bushing is arranged in the bottom of the main body internal layer, and the steel bushing is for connecting conveying lever
Bolt head, the grid below the main body outer layer pools tubular structure, and the tubular structure is connect with the pedestal.
The pedestal is to be woven into woven mesh structure, the thermally treated plate-like at bottom end indent, the bottom with titanium-nickel wire
Seat is internal to be sewed with PFTE or PET choked flow film.
Support rod end also sets up the thorn of buckle, can be pierced into cardiac muscle, and position of the device in heart is stablized in help.
The length of the anchor thorn is 0.5-4 millimeters.
The quantity for the titanium-nickel wire that the main body internal layer uses can be 6-72 root.
The main body outer layer is covered with ePTFE or PET film.
The steel bushing is equipped with internal screw thread, and connect with the bolt head thread.
The pedestal is cut by laser with NiTi pipe, thermally treated at bending, is polymerized to by a plurality of Nitinol manifold
One end is connect with the main body.
Compared with prior art, left ventricle capacity-reduction device of the present invention can be recycled and repeat positioning, simplifies surgical procedure,
Reduce operation risk；
Design according to the present invention is suitable for the left ventricle cavity of various forms and size；
It is firm that the present invention can be provided simultaneously with anchoring, and effectively completely cuts off left ventricle, achievees the purpose that volume reduction；
The repeatable positioning of the present invention.In some cases if placement is ineffective, the case where not freeing conveying lever,
The present invention can be withdrawn in sheath, resetting and placement substantially reduce hand until achieving the effect that satisfied anchoring and volume reduction
Art risk.
Lesser transportation system can be used in the present invention, further decreases damage of the surgical procedure conveying device to blood vessel.
Left ventricle capacity-reduction device of the invention can enter left ventricle through aorta vessel, can also transatrial septal puncture enter a left side
Ventricle, doctor can select suitable modus operandi according to the situation of patient, lower operation risk and complication to patient.
Through the following description and in conjunction with the attached drawings, the present invention will become more fully apparent, these attached drawings are used to explain the present invention
Embodiment.
Detailed description of the invention
The stereogram of Fig. 1 left ventricle capacity-reduction device first embodiment of the present invention.
The front view of Fig. 2 left ventricle capacity-reduction device first embodiment of the present invention.
The sectional front view of Fig. 3 left ventricle capacity-reduction device first embodiment of the present invention.
The upper pseudosection of Fig. 4 left ventricle capacity-reduction device first embodiment of the present invention.
Fig. 5 is the partial enlarged view of Fig. 4.
The front view of Fig. 6 left ventricle capacity-reduction device second embodiment of the present invention.
The sectional front view of Fig. 7 left ventricle capacity-reduction device second embodiment of the present invention.
The stereogram of Fig. 8 left ventricle capacity-reduction device second embodiment of the present invention.
Fig. 9 is partial enlarged view shown in Fig. 8.
The front view of Figure 10 left ventricle capacity-reduction device 3rd embodiment of the present invention.
The sectional front view of Figure 11 left ventricle capacity-reduction device 3rd embodiment of the present invention.
The front view of Figure 12 left ventricle capacity-reduction device fourth embodiment of the present invention.
The sectional front view of Figure 13 left ventricle capacity-reduction device fourth embodiment of the present invention.
The front view of Figure 14 the 5th embodiment of left ventricle capacity-reduction device of the present invention.
The sectional front view of Figure 15 the 5th embodiment of left ventricle capacity-reduction device of the present invention.
The front view of Figure 16 left ventricle capacity-reduction device sixth embodiment of the present invention.
The sectional front view of Figure 17 left ventricle capacity-reduction device sixth embodiment of the present invention.
Specific embodiment
The embodiment of the present invention described referring now to the drawings, similar element numbers represent similar element in attached drawing.Such as
It is upper described:
Embodiment 1:
As shown in Figs. 1-5, left ventricle capacity-reduction device of the invention use two-piece design, respectively based on and pedestal 14.
The main body is divided into main body outer layer 13 and main body internal layer 12, and main body outer layer is integrally cut by laser molding using Nitinol pipe,
Its used Nitinol pipe has diamagnetism, does not influence Magnetic resonance imaging.The structure of main body has fabulous machinery steady
It is qualitative, it is unlikely to deform, is broken and falls apart, keep its structural intergrity.Left ventricle capacity-reduction device according to the present invention can pass through
Aorta or method through the apex of the heart are placed in left ventricle, and pedestal 14 is located at the bottom position of the left apex of the heart, and main body againsts the left heart
The outer wall and interventricular septum of room are placed on above pedestal, and the cardiac muscle inactivated below isolation left ventricle reduces left ventricular volume, places the heart
Dirty further expansion reduces the tension of locular wall.Main body outer layer uses the design of multilayer closed loop grid 16, and the grid is closed loop
Formula design, closed loop design can help agent be unfolded in left ventricle.The top of grid 16 is the support rod 15 having obliquely, branch
The end of strut is provided with hole 17 and anchor thorn 18, and when placing, anchor thorn can be pierced into the cardiac muscle of locular wall, plays anchoring left ventricle and subtracts
The effect of capacitance device places the device in ventricular beats shift.13 upper opening of main body outer layer is cup-shaped, inside and outside to superscribe
PTFE film or other plastic films completely cut off above and below main body outer layer 13, effectively reduce the volume of left ventricle.Main body internal layer
12 are woven using nitinol alloy wire, and titanium-nickel wire passes through hole 17, the position setting steel bushing 20 converged after silk is woven, the steel bushing
20 can connect with the bolt head thread of conveying lever (not showing on figure).The grid of 13 lower section of main body outer layer pools tubulose 19, tubulose 19
It is connect with pedestal 14.The pedestal 14 is to be woven into woven mesh structure with titanium-nickel wire, the thermally treated plate-like at bottom end indent,
The pedestal both ends use steel bushing 21 and steel bushing 22 fixed respectively, and steel bushing 21 connect with main body 19, can be sewed with inside pedestal 14
PFTE or PET choked flow film.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, pulling force effect that steel bushing is connect with the bolt head of conveying lever in main body internal layer 12,
By in the conduit of main body internal layer income conveying lever, the pulling force of the wire of main body internal layer acts on outside main body in the position in hole 17
Layer, main body outer layer is also taken in conduit.Due to there is the threaded connection of the bolt head of steel bushing 20 and conveying lever, so that left ventricle volume reduction
Device and conveying lever secure connection, will not fall off.Left ventricle volume reduction can be filled when left ventricle capacity-reduction device placement location is bad
It sets and withdraws in conduit, release and place again, until success.After left ventricle capacity-reduction device is placed into correct position, rotation
Turn conveying lever, free the threaded connection between the bolt head of conveying lever and steel bushing 20, so that conveying lever and left ventricle capacity-reduction device are de-
From.
Embodiment 2:
As Figure 6-9, left ventricle capacity-reduction device of the invention use two-piece design, respectively based on and pedestal 14.
The main body is divided into main body outer layer 13 and main body internal layer 12, and main body outer layer is integrally cut by laser molding using Nitinol pipe,
Its used Nitinol pipe has diamagnetism, does not influence Magnetic resonance imaging.Main body cage structure has fabulous machinery
Stability is unlikely to deform, is broken and falls apart, and keeps its structural intergrity.Left ventricle capacity-reduction device according to the present invention can be through
It crosses aorta or the method through the apex of the heart is placed in left ventricle, pedestal 14 is located at the position of the left apex of the heart, and main body againsts left ventricle
Outer wall and interventricular septum be placed on above pedestal, the cardiac muscle inactivated below isolation left ventricle reduces left ventricular volume, places heart
Further expansion reduces the tension of locular wall.Main body outer layer uses the design of multilayer closed loop grid 16, and the grid is closed loop
Design, closed loop design can help agent be unfolded in left ventricle.The top of grid 16 is the bar having obliquely, the setting of bar end
There is hole 17, when placing, bar can be pierced into the cardiac muscle of locular wall, played the role of being anchored left ventricle capacity-reduction device, placed the device
In ventricular beats shift.13 upper opening of main body outer layer is cup-shaped, inside and outside to superscribe PTFE film or other plastic films, every
Above and below exhausted main body outer layer 13, the volume of left ventricle is effectively reduced.Main body internal layer is woven using nitinol alloy wire.It is existing
Titanium-nickel wire is passed through to the hole 17 of outer layer, the position of the steel bushing 20 converged after silk is woven, which can be with the bolt head spiral shell of conveying lever
Line connection.The grid of 13 lower section of main body outer layer pools tubulose 19, and tubulose 19 is connect with pedestal 14.The pedestal 14 is to use nickel
Titanium silk is woven into woven mesh structure, and the bottom end of the thermally treated plate-like at bottom end indent, the pedestal 14 also forms column knot
Structure, 14 both ends of pedestal use steel bushing 21 and steel bushing 22 fixed respectively, and steel bushing 21 connect with main body 19, can suture inside pedestal 14
There is PFTE or PET choked flow film.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, the pulling force effect of the connection of the bolt head of 20 conveying lever of steel bushing in main body internal layer 12,
By in the conduit of main body internal layer income conveying lever, the pulling force of the wire of main body internal layer acts on outside main body in the position in hole 17
Layer, main body outer layer is also taken in conduit.Due to there is steel bushing 20 to connect with the bolt head thread of conveying lever, so that left ventricle volume reduction fills
Set with conveying lever secure connection, will not fall off.It can be by left ventricle capacity-reduction device when left ventricle capacity-reduction device placement location is bad
It withdraws in conduit, releases and place again, until success.After left ventricle capacity-reduction device is placed into correct position, rotation
Conveying lever frees the threaded connection between the bolt head of conveying lever and steel bushing 20, so that conveying lever and left ventricle capacity-reduction device are detached from.
Embodiment 3:
As shown in Figure 10,11, left ventricle capacity-reduction device of the invention is on the basis of embodiment 2, main body outer layer 13 and bottom
Seat 14 connects.The pedestal 14 is cut by laser with NiTi pipe, thermally treated at bending, by a plurality of bar or interconnection
Bar pools one end and connect with main body, PFTE or PET choked flow film can be sewed under pedestal 14.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, the pulling force effect of the connection of the bolt head of 20 conveying lever of steel bushing in main body internal layer 12,
Main body internal layer is taken in conduit, the pulling force of the wire of main body internal layer acts on main body outer layer in the position in hole 17, by main body
Outer layer is also taken in conduit.Due to there is steel bushing 20 to connect with the bolt head thread of conveying lever, so that left ventricle capacity-reduction device and conveying
Bar secure connection, will not fall off.Left ventricle capacity-reduction device can be withdrawn conduit when left ventricle capacity-reduction device placement location is bad
It is interior, it releases and places again, until success.After left ventricle capacity-reduction device is placed into correct position, conveying lever, solution are rotated
Threaded connection between the bolt head and steel bushing 20 of de- conveying lever, so that conveying lever and left ventricle capacity-reduction device are detached from.
Embodiment 4:
As shown in Figure 12,13, left ventricle capacity-reduction device of the invention on the basis of example 2, main body outer layer 13 and bottom
Seat 14 connects.The pedestal 14 is to be woven into woven mesh structure with titanium-nickel wire, and the thermally treated column at bottom end indent is described
With being fixed respectively with steel bushing 21 and steel bushing 22, steel bushing 21 is connect with main body 19, and PFTE can be sewed with inside pedestal 14 at pedestal both ends
Or PET choked flow film.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, the pulling force effect of the connection of the bolt head of 20 conveying lever of steel bushing in main body internal layer 12,
Main body internal layer is taken in conduit, the pulling force of the wire of main body internal layer acts on main body outer layer in the position in hole 17, by main body
Outer layer is also taken in conduit.Due to there is the threaded connection of steel bushing 20 and conveying lever, so that left ventricle capacity-reduction device and conveying lever are pacified
Full connection, will not fall off.Left ventricle capacity-reduction device can be withdrawn in conduit when left ventricle capacity-reduction device placement location is bad, weight
New release is placed, until success.After left ventricle capacity-reduction device is placed into correct position, conveying lever is rotated, is freed defeated
The threaded connection between the bolt head of bar and steel bushing 20 is sent, so that conveying lever and left ventricle capacity-reduction device are detached from.
Embodiment 5:
As shown in Figure 14,15, left ventricle capacity-reduction device of the invention use two-piece design, respectively based on and pedestal
14.The main body is divided into main body outer layer 13 and main body internal layer 12, and main body outer layer is integrally laser-cut into using Nitinol pipe
Type, used Nitinol pipe have diamagnetism, do not influence Magnetic resonance imaging.Its rod-like structure has fabulous machinery
Stability is unlikely to deform, is broken and falls apart, and keeps its structural intergrity.Left ventricle capacity-reduction device according to the present invention can be through
It crosses aorta or the method through the apex of the heart is placed in left ventricle, pedestal 14 is located at the position of the left apex of the heart, and main body againsts left ventricle
Outer wall and interventricular septum be placed on above pedestal, the cardiac muscle inactivated below isolation left ventricle reduces left ventricular volume, places heart
Further expansion reduces the tension of locular wall.Main body outer layer uses the design of more support rods 13.The end of support rod 13 is provided with
Hole 17 and anchor thorn 18, when placing, anchor thorn can be pierced into the cardiac muscle of locular wall, played the role of being anchored left ventricle capacity-reduction device, be put
The device is set in ventricular beats shift.13 upper opening of main body outer layer is cup-shaped, inside and outside to superscribe PTFE film or other modelings
Expect film, completely cuts off above and below main body outer layer 13, effectively reduce the volume of left ventricle.Main body internal layer is compiled using nitinol alloy wire
It knits.Titanium-nickel wire is now passed through to the hole 17 of outer layer, the position of the steel bushing 20 converged after silk is woven, which can be with conveying lever
Bolt head thread connection.The grid of 13 lower section of main body outer layer pools tubulose 19, and tubulose 19 is connect with pedestal 14.The pedestal
14 be to be woven into woven mesh structure with titanium-nickel wire, and the thermally treated plate-like at bottom end indent, both ends are fixed with steel bushing 21,22, steel
Set 21 is connect with main body 19, PFTE or PET choked flow film can be sewed with inside pedestal 14.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, the pulling force effect of the connection of the bolt head of 20 conveying lever of steel bushing in main body internal layer 12,
Main body internal layer is taken in conduit, the pulling force of the wire of main body internal layer acts on main body outer layer in the position in hole 17, by main body
Outer layer is also taken in conduit.Due to there is the threaded connection of steel bushing 20 and conveying lever, so that left ventricle capacity-reduction device and conveying lever are pacified
Full connection, will not fall off.Left ventricle capacity-reduction device can be withdrawn in conduit when left ventricle capacity-reduction device placement location is bad, weight
New release is placed, until success.After left ventricle capacity-reduction device is placed into correct position, conveying lever is rotated, is freed defeated
The threaded connection between the bolt head of bar and steel bushing 20 is sent, so that conveying lever and left ventricle capacity-reduction device are detached from.
Embodiment 6:
As shown in Figure 16,17, left ventricle capacity-reduction device of the invention use two-piece design, respectively based on and pedestal
14.The main body is divided into main body outer layer 13 and main body internal layer 12, inside and outside of the main body layer 12 and 13 woven using nitinol alloy wire and
At.The position of the steel bushing 19 and 20 converged after silk is woven, the steel bushing can be connect with the bolt head thread of conveying lever.Main body outer layer 13
The grid of lower section converges to steel bushing 19, and steel bushing 19 is connect with pedestal 14.The pedestal 14 is to be woven into mesh grid with titanium-nickel wire
Structure, the thermally treated plate-like at bottom end indent, both ends are fixed with steel bushing 21,22, and steel bushing 21 is connect with main body 19, in pedestal 14
Portion can be sewed with PFTE or PET choked flow film.
Left ventricle capacity-reduction device of the invention can be connect by steel bushing 20 with the bolt head of conveying lever.In conveying lever push,
Conveying lever applies active force in the main body internal layer of left ventricle capacity-reduction device, is pushed to left ventricle capacity-reduction device through the apex of the heart through conduit
Suitable position inside left ventricle.In recycling, the pulling force effect of the connection of the bolt head of 20 conveying lever of steel bushing in main body internal layer 12,
Main body internal layer is taken in conduit, the pulling force of the wire of main body internal layer acts on main body outer layer in the position in hole 17, by main body
Outer layer is also taken in conduit.Due to there is the threaded connection of steel bushing 20 and conveying lever, so that left ventricle capacity-reduction device and conveying lever are pacified
Full connection, will not fall off.Left ventricle capacity-reduction device can be withdrawn in conduit when left ventricle capacity-reduction device placement location is bad, weight
New release is placed, until success.After left ventricle capacity-reduction device is placed into correct position, conveying lever is rotated, is freed defeated
The threaded connection between the bolt head of bar and steel bushing 20 is sent, so that conveying lever and left ventricle capacity-reduction device are detached from.
The above disclosure is only a preferred embodiment of the invention, cannot limit the right of the present invention with this certainly
Range, therefore according to equivalent variations made by scope of the present invention patent, it is still within the scope of the present invention.
Claims (7)
1. a kind of left ventricle capacity-reduction device characterized by comprising main body and pedestal, the main body include main body outer layer and master
Internal layer, the main body outer layer are Nitinol pipe through cup-shaped made of laser cutting, heat treatment, polishing；The main body outer layer
Lower end be closed loop structure, the upper end of the main body outer layer is several support rods, and the end of the support rod is equipped with a hole, uses
In connecting the main body internal layer, and the main body internal layer is titanium-nickel wire braiding structure, titanium-nickel wire used pass through the hole with it is described
Support rod connection, collects after the both ends of titanium-nickel wire are woven in the bottom of the main body internal layer, and at the bottom of the main body internal layer
A steel bushing is arranged in portion, and the steel bushing is used to connect the bolt head of conveying lever, and the grid below the main body outer layer pools tubulose knot
Structure, the tubular structure are connect with the pedestal；The main body outer layer is covered with the modeling that can completely cut off above and below main body outer layer
Expect film, the plastic film is between the main body internal layer and main body outer layer.
2. left ventricle capacity-reduction device as described in claim 1, it is characterised in that: the pedestal is the volume that titanium-nickel wire is woven into
Web structure, the thermally treated plate-like at bottom end indent, the chassis interior are sewed with PFTE or PET choked flow film.
3. left ventricle capacity-reduction device as described in claim 1, it is characterised in that: support rod end also sets up the thorn of buckle, uses
In being pierced into cardiac muscle, to stablize position of the left ventricle capacity-reduction device in heart.
4. left ventricle capacity-reduction device as claimed in claim 3, it is characterised in that: the length of the thorn is 0.5-4 millimeters.
5. left ventricle capacity-reduction device as described in claim 1, it is characterised in that: the number for the titanium-nickel wire that the main body internal layer uses
Amount is 6-72 root.
6. left ventricle capacity-reduction device as described in claim 1, it is characterised in that: the steel bushing is equipped with internal screw thread, is used for and institute
State the connection of bolt head thread.
7. left ventricle capacity-reduction device as described in claim 1, it is characterised in that: the pedestal is cut with NiTi pipe laser
It cuts, it is thermally treated at bending, one end is pooled by a plurality of bar and is connect with the main body.
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| CN106214289A (en) * | 2016-09-05 | 2016-12-14 | 广东脉搏医疗科技有限公司 | A kind of heart volume reduction implant |
| CN111513773B (en) * | 2020-03-30 | 2022-01-14 | 北京大学深圳研究生院 | Recoverable ventricular isolation device, recovery device and system |
| EP4029477A4 (en) * | 2020-11-23 | 2022-11-02 | Jiangsu Trulive Medtech Co., Ltd | Mitral valve device implanted via atrial septum, and implantation method |
| CN112807047A (en) * | 2021-01-11 | 2021-05-18 | 上海傲流医疗科技有限公司 | Recoverable left ventricle isolating device |
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| CN104287804A (en) * | 2014-10-27 | 2015-01-21 | 梁巧英 | Biological cavity blocking device |
| CN104706444A (en) * | 2015-03-03 | 2015-06-17 | 上海形状记忆合金材料有限公司 | Volume reduction device for left ventricle |
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| US7044134B2 (en) * | 1999-11-08 | 2006-05-16 | Ev3 Sunnyvale, Inc | Method of implanting a device in the left atrial appendage |
| JP5875986B2 (en) * | 2009-10-26 | 2016-03-02 | カーディオキネティックス・インコーポレイテッドＣａｒｄｉｏｋｉｎｅｔｉｘ， Ｉｎｃ． | Ventricular volume reduction |
| US10123805B2 (en) * | 2013-06-26 | 2018-11-13 | W. L. Gore & Associates, Inc. | Space filling devices |
| CN104352261B (en) * | 2014-10-13 | 2017-11-03 | 深圳市科奕顿生物医疗科技有限公司 | Occluder for left auricle |
| CN104739460B (en) * | 2015-01-28 | 2018-04-10 | 深圳市科奕顿生物医疗科技有限公司 | Left ventricle capacity-reduction device |
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| CN104287804A (en) * | 2014-10-27 | 2015-01-21 | 梁巧英 | Biological cavity blocking device |
| CN104706444A (en) * | 2015-03-03 | 2015-06-17 | 上海形状记忆合金材料有限公司 | Volume reduction device for left ventricle |
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Address after: 518118 Guangdong province Shenzhen City Ping mountain Pingshan Street industrial zone planning five road No. 1 Applicant after: Biological medical science and technology company limited of grand of section of Shenzhen Address before: 1301-1, Silver Star Science and technology building in C District of Longhua District Guanlan Street sightseeing road 518000 Guangdong city of Shenzhen province 806 Applicant before: Biological medical science and technology company limited of grand of section of Shenzhen |
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