CN104352261B - Occluder for left auricle - Google Patents
Occluder for left auricle Download PDFInfo
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- CN104352261B CN104352261B CN201410537627.0A CN201410537627A CN104352261B CN 104352261 B CN104352261 B CN 104352261B CN 201410537627 A CN201410537627 A CN 201410537627A CN 104352261 B CN104352261 B CN 104352261B
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- disk
- left auricle
- support bar
- occluder
- grappling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12122—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12177—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
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- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
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- Reproductive Health (AREA)
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- Cardiology (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
Abstract
The invention discloses a kind of occluder for left auricle, including：Block disk, terminal pad and anchor disk, the closure disk and terminal pad are woven using nitinol alloy wire, it is thermally treated to be shaped as disk-like structure, the diameter of the terminal pad is close to the diameter of the anchor disk, and during the terminal pad expansion, the terminal pad provides support to anchor disk, to stablize fixation of the anchor disk in left auricle of heart, described anchor disk includes the support bar that central end and Duo Gen are connected with the central end being connected with the terminal pad.The present invention is a kind of inaccessible left auricle of heart, blocks thrombus outflow effect in left auricle of heart good, repeatable positioning, fixing-stable, fatigue proof occluder for left auricle.
Description
Technical field
The present invention relates to a kind of inaccessible left auricle of heart, block thrombus outflow effect in left auricle of heart good, repeatable positioning is fixed stably
Fixed, fatigue proof occluder for left auricle.
Background technology
At present, with the development of intervention apparatus, what many surgical operations can not be treated, which cure the disease, is cured.These are cured the disease
Treatment method of the treatment relative to surgical operation, the wound of intervenient cure is small, recovers fast, curative effect is good.By nearly half
The development in century, intervenient cure has obtained swift and violent development, also generates various interventional medical device products.So that
Increasing cure the disease obtains medical treatment with patient.
Auricular fibrillation (atrial fibrillation) is one of most common arrhythmia cordis, except the discomfort that palpitaition symptom is brought, thromboembolism
It is the topmost harm of atrial fibrillation etc. complication.In non-valvular and non-nonrheumatic atrial fibrillation patient, about 90% thrombus source
From left auricle of heart.Thromboembolic events and cerebral apoplexy occur for annual 5% patients with atrial fibrillation that there are about.And fatal rate is up to caused by cerebral apoplexy
50%.Therefore, how to prevent and treat atrial fibrillation thrombus caused by cerebral apoplexy there is important clinical meaning.Prevention and treatment at present
The method of atrial fibrillation thrombus has surgical operation, drug therapy and interventional therapy method.The wherein inaccessible left auricle of heart of surgical method, due to
Its wound is big, risk is high etc., and reason is not widely used.At present, what the method for fibrillation patient prevention headstroke had is most universal
Method be Long-term Oral anticoagulation medicine, but anticoagulation medicine has the risk for causing bleeding, there are about 14%~44% patient
It can not receive long-term agents anticoagulant therapy because there is contraindication.Recent domestic has developed a kind of state-of-the-art PCI
Special occluder for left auricle, is implanted in left auricle of heart by method by tiny conduit, inaccessible left auricle of heart, prevents and treats atrial fibrillation
Cardioversion and cerebral apoplexy occur for patient.This treatment method wound is small, and risk is low, recovers fast, curative effect is good, so that as prevention
The preferred treatment method with cerebral apoplexy caused by treatment atrial fibrillation.
Such current apparatus can be broadly divided into Weaving type, cutting-type and mixed type from the point of view of structure.The left heart of these types
Ear plugging device can be sent into plugging device in left auricle of heart by the method for intubation intervention, realize left atrial appendage occlusion.But all deposit
In suitable limitation.Everyone left auricle of heart anatomical structure is complicated, different, there is ellipticity, peanut shape etc..Left auricle of heart
Inwall is uneven, in irregular shape, and left auricle of heart wall is thin.So being difficult to neither piercing through heart wall, the left heart can be firmly anchored on again
Do not fallen off in ear, be finally reached preferable plugging effect.
Weaving type occluder for left auricle as designed by patent of invention CN200610037789 and CN200580002183.He
Using the rough structure of the fixation panel surface of plugging device come grappling plugging device, closure disk is blocked in left auricle of heart mouthful, is reached
To the effect of occlusion.The design advantage of this structure is simple in construction, and difficulty of processing is small, and cost is low.But the fixation of braiding
The grappling dynamics of disk is relatively low, it is difficult to adapt to different left auricle of heart form.Grappling hook is sutured on fixed disk, in fixation
Disk is difficult still to be pierced into left auricle of heart wall in the case of being squeezed deformation, realizes stable fix.And fixed disk is in left auricle of heart
The shape for blocking disk can be influenceed by being inside squeezed after deformation, cause plugging effect not good.
Cutting-type occluder for left auricle as involved by patent of invention CN200410059976 and CN99815453.They will
Nickel-titanium metal pipe is cut, heat-treating profiled into designed shape.It is designed with and outwards sticks up at the position contacted with left auricle of heart inwall
The grappling thorn risen, is pierced into left auricle of heart inwall, realizes stable fix.Choked flow film is generally sewed with the grid framework of cutting-type,
Realize the effect of left atrial appendage occlusion.The advantage of this structure design is that whole plugging device is integrally formed, and rigidity is stronger, easily
Fixed in left auricle of heart inwall, designed grappling thorn is easily pierced into left auricle of heart inwall, stable to fix, and prevents plugging device from coming off.
But deformability is limited in shape for cutting-type occluder for left auricle, it is impossible to adapt to different left auricle of heart form so that
Its use is very restricted.Cutting-type occluder for left auricle is after plug such as left auricle of heart, and the part in atrium sinistrum is usual
Depression can be formed with atrial wall ratio, new " left auricle of heart " region, the new thrombotic risk of increase is formed.Cutting-type left auricle of heart
The grappling thorn of plugging device is typically to stab atrium sinistrum, plays stable plugging device, prevents plugging device from coming off.But stab atrium sinistrum
Grappling thorn can be stuck in sheath tube wall edge so that plugging device can not be reclaimed in resetting when reclaiming plugging device, carry out repeating fixed
Position.
Mixed type occluder for left auricle as involved by patent of invention CN201110146287 and CN103099652A.At this
Closure disk is generally sewed with choked flow film, for inaccessible left auricle of heart using the pattern of braiding in closure disk in a little designs.And fix
Disk has the cutting of nickel-titanium metal pipe, heat-treating profiled into designed shape.It is oriented in the position design contacted with left auricle of heart inwall
The grappling thorn of outer tilting, is pierced into left auricle of heart inwall, realizes stable fix.Mixed type occluder for left auricle effectively solves cutting
Most of problem of type occluder for left auricle.But the grappling thorn of fixed disk is typically to stab such as in CN103099652A
Atrium sinistrum, plays stable plugging device, prevents plugging device from coming off.But the grappling thorn for stabbing atrium sinistrum reclaims envelope in resetting
Sheath tube wall edge can be stuck in during stifled device so that plugging device can not be reclaimed, carry out resetting.And this mixed type left atrial appendage occlusion
The usual deformation of fixed disk of device is larger, to overturn the direction of grappling thorn, causes the tension force and deformation quantity of fixed disk to reach material
Limiting value.Fatigue strength of this apparatus in Permanent implantation is poor, is easily broken, and punctures its hetero-organization such as heart, jeopardizes
Life.
Therefore, the advantage and disadvantage of comprehensive various occluder for left auricle, develop it is a kind of can effectively inaccessible left auricle of heart, repeat and determine
Position, it is stable fixed, can Permanent implantation occluder for left auricle.
Therefore, need a kind of inaccessible left auricle of heart badly, block thrombus outflow effect in left auricle of heart good, repeatable positioning is fixed stably
Fixed, fatigue proof occluder for left auricle.
The content of the invention
It is an object of the invention to provide a kind of occluder for left auricle, block thrombus outflow effect in left auricle of heart good, it is repeatable
Positioning, fixing-stable, fatigue proof occluder for left auricle.
To achieve these goals, the technical scheme that provides of the present invention is：A kind of occluder for left auricle is provided, its feature exists
In, including：Disk, terminal pad and anchor disk are blocked, the closure disk and terminal pad are woven using nitinol alloy wire, thermally treated
Disk-like structure is shaped as, to play the effect of closure, PTFE or PET choked flow films can be sutured on closure disk.For reduction choked flow film
Surface thrombus originality, accelerates closure panel surface endothelialization.Such choked flow film can using electrostatic spinning spinning, and through low temperature etc. from
Sub- surface active is formed.PTFE or PET choked flow films can be sutured in terminal pad, the outflow of thrombus in left auricle of heart is prevented.The company
The diameter of disk is connect close to the diameter of the anchor disk, during the terminal pad expansion, the terminal pad provides support to anchor disk, with
Stablize fixation of the anchor disk in left auricle of heart, described anchor disk includes the central end being connected with the terminal pad and many
The support bar that root is connected with the central end.
The cavity for suturing PTFE or PET choked flow films in anchor disk is additionally provided with the support bar, the left heart is prevented
The outflow of thrombus in ear.To stablize the cross-fire shape arrangement of support bar, the support bar has crossover sites, the cross part
Position sets limiting component.Not only ensure that support bar is arranged into cross-fire, support bar can also be avoided to be tangled in placement process
Together.
The support bar can be in shaft-like, branch-like or latticed, and the end of the support bar can be in interior bending, flexible pellet
Spring shape is spherical, and the side of the support bar from central end circle is sent, across the center of the central end to the circle
Offside, many support bars in radial arrangement is intersected, set at least one on piece support bar of wherein at least together
Individual grappling thorn, the grappling is pierced towards the closure disk.
The number of the support bar should be odd number.
The length of the anchor disk thorn is 0.5-4 millimeters.
Also include push rod, the threaded one end of the closure disk connects the push rod, and one end of the closure disk is equipped with
Multiple wires, the wire has the larger end of volume, and the end can be stuck between the connector of push rod, the envelope
Stifled disk and the push rod are flexible connection.
Described anchor disk is cut by NiTi pipe, and heat-treating profiled mode is made.
Described anchor disk is woven by titanium-nickel wire, and heat-treating profiled mode is made.
Support bar is passed through in the stopper slot of the limiting component one by one after intersecting, and the limiting component is welded or punching press is solid
It is scheduled in the anchor disk.
The support bar finalizes the angle of grappling thorn using die ＆ mold treatment using grappling thorn is cut by laser out, described
Grappling thorn is flared out, and towards the direction of the closure disk, and the root that the grappling is pierced is on the support bar, the grappling
Thorn is flared out automatically in the case where not being stressed, and the grappling thorn can be recycled on the support bar during compression, the branch
The end of strut is in the shape that curves inwardly.
The closure disk is woven into woven mesh structure by titanium-nickel wire, thermally treated discoid, and two ends are solid by steel bushing
Fixed, one end of the closure disk and terminal pad are connected with steel bushing；The terminal pad is also to be woven into mesh grid by titanium-nickel wire, warp
Plate-like is heat-treated to, and two ends are fixed by steel bushing.
Compared with prior art：
Occluder for left auricle of the present invention, the anchor disk structural deformation is soft, stable, the fatigue performance pole of Permanent implantation
It is good, it is suitable for the left auricle of heart cavity of various forms and size；
The present invention designs for three-stage, is suitable for the left auricle of heart cavity of various forms and size；
The present invention can be provided simultaneously with grappling and consolidate, and effectively inaccessible left auricle of heart；
The repeatable positioning of the present invention.If it is not good to place effect in some cases, the situation of push rod is not being freed,
The present invention can be withdrawn in sheath, resetting and placement, until reaching the effect of satisfied grappling and occlusion, substantially reduce hand
Art risk.
Less induction system can be used in the present invention, further reduces damage of the surgical procedure conveying device to blood vessel.
It is flexibly connected between occluder for left auricle and push rod of the present invention, greatly reduces in surgical procedure push rod to this hair
The tension force of bright application so that the position that the present invention is placed is more accurate.
By following description and with reference to accompanying drawing, the present invention will become more fully apparent, and these accompanying drawings are used to explain the present invention
Embodiment.
Brief description of the drawings
Fig. 1 is the schematic diagram of one embodiment of left auricle of heart fixator of the present invention.
Fig. 2 is the schematic diagram of occluder for left auricle as shown in Figure 1.
Fig. 3 is the block schematic illustration of another form of expression of occluder for left auricle as shown in Figure 1.
Fig. 4 is the block schematic illustration of the second embodiment of occluder for left auricle of the present invention.
Fig. 5 is the schematic diagram of three embodiments of left auricle of heart fixator of the present invention.
Fig. 6 a are the top view of one embodiment of the closure disk of occluder for left auricle of the present invention.
Fig. 6 b are the front view of one embodiment of the closure disk of occluder for left auricle of the present invention.
Fig. 7 a are the top view of one embodiment of the terminal pad of occluder for left auricle of the present invention.
Fig. 7 b are the front view of one embodiment of the terminal pad of occluder for left auricle of the present invention.
Fig. 8 a are the front view of one embodiment of the anchor disk of occluder for left auricle of the present invention.
Fig. 8 b are the stereogram of one embodiment of the anchor disk of occluder for left auricle of the present invention.
The anchor disk of Fig. 9 a present invention occluder for left auricle as shown in Figure 1 has just gone out the view of sheath.
The half of the anchor disk of Fig. 9 b present invention occluder for left auricle as shown in Figure 1 goes out the view of sheath.
The anchor disk of Fig. 9 c present invention occluder for left auricle as shown in Figure 1 goes out the view of sheath completely.
The limiting component solid signal of the anchor disk crossover sites of Figure 10 present invention occluder for left auricle as shown in Figure 1
Figure.
The limiting component of the anchor disk crossover sites of the occluder for left auricle of Figure 11 present invention and the assembling of anchor disk are amplified
Schematic diagram.
Position view of the occluder for left auricle of Figure 12 present invention in left auricle of heart anatomical structure.
Figure 13 a are the occluder for left auricle of the present invention and the connection diagram of push rod.
Figure 13 b free schematic diagram for occluder for left auricle and push rod of the invention.
The connector three-dimensional view of the push rod of the occluder for left auricle of Figure 14 present invention.
Embodiment
Element numbers similar in embodiments of the invention, accompanying drawing, which are described, with reference now to accompanying drawing represents similar element.
Embodiment 1：
As shown in Fig. 1, Fig. 2 and Fig. 3, occluder for left auricle involved in the present invention includes closure disk 11, with closure disk 11
The terminal pad 22 of connection and the anchor disk 33 being connected with terminal pad 22, wherein as shown in fig. 6, closure disk 11 is woven into titanium-nickel wire
Woven mesh structure, thermally treated discoid, two ends steel bushing 111 is fixed, and blocks one end and the steel bushing 111 of terminal pad 22 of disk 11
Connection, the other end, which is provided with screw thread or one end as shown in Figure 13 a, 13b, has the wire 121 of bulb a plurality of, with conveying device
Push rod 122 connect, as shown in figure 14, there is depression 124 end of connector 123 for the connector 123 of push rod 122, even
One end male cooperation with closure disk 11 when blocking disk 11 is connect, there are multiple rectangular recess 125 and spherical female in the outer of connector 123
Groove 126, and rectangular recess 125 connected with ball recess 126, and the wire 121 for having bulb is pressed into the groove of connector 123
Afterwards, blocked with a matched sleeve pipe 127, play a part of connection, when freeing, sleeve pipe 127 is dropped back, wire
121 ejection rectangular recess 125 are freed with push rod 122；As shown in Fig. 7 a and Fig. 7 b, likewise, terminal pad 22 is also to use NiTi
Silk is woven into woven mesh structure, and thermally treated discoid, two ends steel bushing 221 is fixed, diameter and the anchor disk 33 of terminal pad 22
Quite, the inside in anchor disk 33, the outer 222 of terminal pad 22 can play a supporting role to the support bar 331 of anchor disk 33,
PFTE or PET choked flow films are sewed with respectively inside closure disk 11 and terminal pad 22.As shown in Fig. 8 a, Fig. 8 b, anchor disk 33 is to use
Many support bars 331 of a piece NiTi pipe cutting, use the thermally treated shape into shown in figure of mould.Anchor disk 33
Central end 332 is welded to be connected with terminal pad 22.
In embodiment 1, although support bar 331 has 9, but it be able to can be changed according to the requirement of actual mechanical property and specification
Become the quantity of support bar 331.The side of this nine support bars 331 from the circle of central end 332 is sent, across central end 332
Center to the offside of the circle, and in bending, many support bars 331 are together in radial arrangement is intersected, in support bar 331
On be also provided with cavity 333 be used in anchor disk 33 suture PTFE or PET choked flow films, prevent left auricle of heart in thrombus streams
Go out.As shown in Figure 10 and Figure 11, arranged to stablize the cross-fire shape of support bar 331, crossover sites can be provided with limiting section
Part 334, not only ensures that support bar 331 is arranged into cross-fire, support bar 331 can also be avoided to be tangled in placement process one
Rise, support bar 331 passes through the stopper slot 335 of limiting component 334 one by one after intersecting, limiting component 334 is welded or punching press is fixed
In anchor disk 33, on support bar 331,336 shapes are pierced using grappling is cut by laser out, anchor is finalized using die ＆ mold treatment
Surely the angle of thorn 336, grappling thorn 336 is flared out, and towards the direction of closure disk 11, the root of grappling thorn 336 is in support bar
On 331, grappling thorn 336 is flared out automatically in the case where not being stressed, and grappling thorn 336 can be recycled to support bar during compression
On 331, the end 337 of support bar 331 curves inwardly shape.
As shown in Fig. 9 a, 9b, 9c, anchor disk 33 has following spy in the process for entering sheath 44 and being come out in sheath 44
Point：In order to be able to which clear explanation anchor disk 33 is passed in and out the support bar of anchor disk 33 in the process of sheath, Fig. 9 a, Fig. 9 b and Fig. 9 c
331 are reduced to two, and support bar 331 is straightened and cross-shaped in sheath, towards central end 332 at grappling thorn 336
Opposite oblique inner side direction.Will not scratch sheath inside pipe wall during being pushed in sheath 44.As illustrated in fig. 9, in push rod 122
Thrust under, the elbow 337 of the end of support bar 331 slowly releases sheath 44, along direction A deploy.As shown in figure 9b, after
Continuous to push push rod 122, support bar 331 continues along direction A deployed conditions.Now, about 90 degree of the upset of grappling thorn 336, close to hang down
Directly in push rod 122.Push rod 122 continues to push power, and by the completely out sheath 44 of anchor disk 33, support bar 331 continues
It is in such as Fig. 9 c states along direction A expansion, now, anchor disk 33 is fully deployed, grappling thorn 336 overturns about 90 degree again, in grappling
The outside of disk 33, towards the oblique lateral direction of central end 332, stabs left auricle of heart inwall, is fixed on left auricle of heart intracavitary, hereafter, even
Connect disk 22 in the lower section of anchor disk 33 to deploy, not only provide the flexible connection of closure disk 11 and anchor disk 33 to adapt to various shapes
The left auricle of heart cavity of state, can also give the support force of support bar 331, further fixation of the stable anchor disk 33 in left auricle of heart.Returning
Process when receiving anchor disk 33 releases each stage of process of sheath 44 on the contrary, anchor disk 33 is pushed bar 122 with anchor disk 33
Sheath 44 is pulled in, outstanding feature is that oblique lateral direction when grappling thorn 336 is by deploying towards central end 332 overturns direction
The opposite oblique inner side direction of central end 332, this process ensures that grappling thorn 336 scratch left auricle of heart wall and can will not smoothly enter
Enter sheath 44.The occluder for left auricle of the present embodiment not only can guarantee that repeatable positioning function of the anchor disk 33 in left auricle of heart,
Also greatly reduce damage of the apparatus to left auricle of heart wall, reduce the risk and complication of operation.
Embodiment 2：
As shown in figure 4, occluder for left auricle of the present invention includes closure disk 11, with the terminal pad 22 that is connected of closure disk 11 and with
The anchor disk 33 that terminal pad 22 is connected, closure disk 11 and the terminal pad 22 being connected with blocking disk 11 use unitary design, use
Titanium-nickel wire is woven into woven mesh structure, and two ends steel bushing 111 is fixed, thermally treated into double disk structure, in closure disk 11 and connection
There is relatively fine waist 128 between disk 22, one end connection anchor disk 33 of terminal pad 22 as shown in Figure 13 a and 13b, blocks disk
11 other end is provided with screw thread, and one end has the wire 121 of bulb a plurality of, is connected with the push rod 122 of conveying device, closure
PFTE or PET choked flow films are sewed with inside disk 11 and terminal pad 22 respectively, anchor disk 33 is formed with a NiTi pipe cutting
Many support bars 331, use the thermally treated shape into shown in figure of mould.The support bar 331 of anchor disk 33 is from central end
The side of 332 circles is sent, across the center of central end 332 to the offside of the circle, and in bending, many support bars
331 together in intersection radial arrangement.Cavity 333 is also provided with support bar 331 to be used to suture in anchor disk 33
PTFE or PET choked flow films, prevent the outflow of thrombus in left auricle of heart.As shown in Figure 10 and Figure 11, to stablize the intersection of support bar 331
Radial arrangement, can be provided with limiting component 334 in crossover sites.Not only ensure that support bar 331 is arranged into cross-fire, may be used also
To avoid support bar 331 from being tangled together in placement process.Support bar 331 passes through the limit of limiting component 334 one by one after intersecting
In the groove 335 of position, limiting component 334 is welded or punching press is fixed in anchor disk 33.On support bar 331, laser cutting is utilized
Go out grappling and pierce 336 shapes, the angle of grappling thorn 336 is finalized using die ＆ mold treatment.Grappling thorn 336 is flared out, direction
The direction of disk 11 is blocked, the root of grappling thorn 336 is on support bar 331, and grappling thorn 336 is not in the case where being stressed from trend
Open outside, grappling thorn 336 can be recycled on support bar 331 during compression.The end 337 of support bar 331 curves inwardly shape.
Embodiment 3：
As shown in Fig. 5,6a and 6b, occluder for left auricle involved in the present invention includes closure disk 11, connects with closure disk 11
The terminal pad 22 connect and the anchor disk 33 being connected with terminal pad 22, closure disk 11 and the terminal pad 22 being connected with blocking disk 11 are used
Unitary design, woven mesh structure is woven into using titanium-nickel wire, and two ends steel bushing 111 is fixed, thermally treated into T-shaped dish structure,
Two ends are recessed flexible and retractility elastomer, and one end connection anchor disk 33 of terminal pad 22 blocks the another of disk 11
One end, which is provided with screw thread or one end as shown in Figure 13 a, 13b, has the wire 121 of bulb a plurality of, the push with conveying device
Bar 122 is connected, and is sewed with PFTE or PET choked flow films respectively inside closure disk 11 and terminal pad 22, anchor disk 33 is with a nickel
Many support bars 331 of titanium tube cutting, use the thermally treated shape into shown in figure of mould.The support bar of anchor disk 33
331 send from the side of the circle of central end 332, across the center of central end 332 to the offside of the circle, and in bending
Shape, many support bars 331 are together in intersection radial arrangement.Cavity 333 is also provided with support bar 331 to be used in anchor
PTFE or PET choked flow films are sutured on price fixing, the outflow of thrombus in left auricle of heart is prevented.As shown in Figure 10 and Figure 11, it is stable support
The cross-fire shape arrangement of bar 331, can set the part of limited location 334 in crossover sites.Not only ensure that support bar 331 is put into intersection
Arrangement is penetrated, support bar 331 can also be avoided to be tangled together in placement process.Support bar 331 passes through spacing one by one after intersecting
In the stopper slot 335 of part 334, limiting component 334 is welded or punching press is fixed in anchor disk 33.On support bar 331, profit
336 shapes are pierced with grappling is cut by laser out, the angle of grappling thorn 336 is finalized using die ＆ mold treatment, grappling thorn 336 is outside
Open, towards the direction of closure disk 11, the root of grappling thorn 336 is on support bar 331, and grappling thorn 336 is in the feelings not being stressed
It is flared out automatically under condition, grappling thorn 336 can be recycled on support bar 331 during compression.The end of support bar 331 is after hot melt
Bulb 338 is formed, to reduce the risk for stabbing tissue.
As shown in figure 12, placement schematic diagram of the occluder for left auricle of the present invention in atrium sinistrum LA left auricle of heart LAA.This hair
Flexible and retractility the terminal pad 22 of bright occluder for left auricle so that anchor disk 33 can be placed on deeper according to clinic needs
Or shallower position.
In summary, occluder for left auricle of the present invention includes closure disk, terminal pad and anchor disk, with good elasticity
With inaccessible performance, the plugging device overall structure stability is good, repeats positioning, and grappling is consolidated, and is suitable for various left auricle of heart forms,
Operating difficulty and the damage to tissue are reduced, the plugging device includes having favorable elasticity and the interior closure disk for being sewed with choked flow film,
It blocks disk by one or segmentation one flexible terminal pad of connection, and the terminal pad has good deformability, made
Obtain the occluder for left auricle and adapt to various left auricle of heart forms, the anchor disk being connected with terminal pad is overall to tie with multiple support bars
The stability of structure is good.There is grappling thorn on the support bar of the anchor disk, to offside can do 180 degree upset with support bar, increase
The anchoring ability of strong anchoring thorn, reduces damage of the grappling thorn to tissue so that the plugging device has the function of resetting.It is this
Structure design of the support bar across center curvature to offside, the deformation of support bar is small, and stress is small, and reduction Permanent implantation is broken
Risk, also cause the present invention occluder for left auricle use less induction system.
Therefore, the present invention has advantages below：
Occluder for left auricle of the present invention, the anchor disk structural deformation is soft, stable, the fatigue performance pole of Permanent implantation
It is good, it is suitable for the left auricle of heart cavity of various forms and size；
The present invention designs for three-stage, is suitable for the left auricle of heart cavity of various forms and size；
The present invention can be provided simultaneously with grappling and consolidate, and effectively inaccessible left auricle of heart；
The repeatable positioning of the present invention.If it is not good to place effect in some cases, the feelings of conveying push rod are not being freed
Condition, can withdraw the present invention in sheath, and resetting and placement, until reaching the effect of satisfied grappling and occlusion, are dropped significantly
Low operation risk.
Less induction system can be used in the present invention, further reduces damage of the surgical procedure conveying device to blood vessel.
It is flexibly connected between occluder for left auricle and push rod of the present invention, greatly reduces in surgical procedure push rod to this hair
The tension force of bright application so that the position that the present invention is placed is more accurate.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modification, equivalent substitute and improvement made within refreshing and principle etc., should be included in the scope of the protection.With
Upper disclosed only the preferred embodiments of the present invention, can not limit the interest field of the present invention, therefore with this certainly
The equivalent variations made according to scope of the present invention patent, still belong to the scope that the present invention is covered.
Claims (10)
1. a kind of occluder for left auricle, it is characterised in that including：Block disk, terminal pad and anchor disk, the closure disk and connection
Disk is woven using nitinol alloy wire, thermally treated to be shaped as disk-like structure, and the diameter of the terminal pad is close to the anchor disk
Diameter, during terminal pad expansion, the terminal pad gives anchor disk to provide support, to stablize the anchor disk in left auricle of heart
Fixation, described anchor disk includes the branch that central end and Duo Gen are connected with the central end being connected with the terminal pad
Strut；The support bar has crossover sites, and the crossover sites set limiting component；The support bar can be in shaft-like or branch
Shape, the end of the support bar can be in interior bending, flexure spring shape or spherical, the support bar from central end circle one
Side is sent, across the center of the central end to the offside of the circle, and many support bars are together in the radial row of intersection
At least one grappling is set to pierce on row, piece support bar of wherein at least, the grappling is pierced towards the closure disk.
2. occluder for left auricle as claimed in claim 1, it is characterised in that：It is additionally provided with the support bar in grappling
The cavity of PTFE or PET choked flow films is sutured on disk.
3. occluder for left auricle as claimed in claim 1, it is characterised in that：The number of the support bar should be odd number.
4. occluder for left auricle as claimed in claim 1, it is characterised in that：The length of the anchor disk thorn is 0.5-4 millimeters.
5. occluder for left auricle as claimed in claim 2, it is characterised in that：Also include push rod, one end of the closure disk
The push rod is threadedly coupled, one end of the closure disk is equipped with multiple wires, and the wire has the larger end of volume,
The end can be stuck between the connector of push rod, and the closure disk and the push rod are flexible connection.
6. the occluder for left auricle as described in claim 1 or 4, it is characterised in that：Described anchor disk is cut by NiTi pipe,
Heat-treating profiled mode is made.
7. the occluder for left auricle as described in claim 1 or 4, it is characterised in that：Described anchor disk is woven by titanium-nickel wire,
Heat-treating profiled mode is made.
8. the occluder for left auricle as described in claim 1 or 4, it is characterised in that：Support bar passes through the limit one by one after intersecting
In the stopper slot of position part, the limiting component is welded or punching press is fixed in the anchor disk.
9. occluder for left auricle as claimed in claim 3, it is characterised in that：The support bar is using being cut by laser out grappling
Thorn, the angle of grappling thorn is finalized using die ＆ mold treatment, and the grappling thorn is flared out, towards the direction of the closure disk,
And the root of the grappling thorn, on the support bar, the grappling thorn is flared out automatically in the case where not being stressed, and is pressed
The grappling thorn can be recycled on the support bar during contracting, and the end of the support bar is in the shape that curves inwardly.
10. occluder for left auricle as claimed in claim 4, it is characterised in that：The closure disk is woven into by titanium-nickel wire
Web structure, it is thermally treated discoid, and two ends are fixed by steel bushing, block one end and the connection of terminal pad steel bushing of disk；It is described
Terminal pad is also to be woven into mesh grid by titanium-nickel wire, thermally treated discoid, and two ends are fixed by steel bushing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410537627.0A CN104352261B (en) | 2014-10-13 | 2014-10-13 | Occluder for left auricle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410537627.0A CN104352261B (en) | 2014-10-13 | 2014-10-13 | Occluder for left auricle |
Publications (2)
| Publication Number | Publication Date |
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| CN104352261A CN104352261A (en) | 2015-02-18 |
| CN104352261B true CN104352261B (en) | 2017-11-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410537627.0A Active CN104352261B (en) | 2014-10-13 | 2014-10-13 | Occluder for left auricle |
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| CN104958087B (en) | 2015-07-28 | 2018-09-25 | 杭州诺茂医疗科技有限公司 | A kind of occluder for left auricle |
| CN106618659B (en) * | 2015-10-28 | 2019-04-26 | 先健科技(深圳)有限公司 | Occluder for left auricle |
| CN114711872B (en) * | 2015-12-29 | 2025-01-03 | 深圳市科奕顿生物医疗科技有限公司 | Left Atrial Appendage Occluder |
| CN106901792B (en) | 2015-12-29 | 2019-11-01 | 深圳市科奕顿生物医疗科技有限公司 | Occluder for left auricle |
| CN106923884B (en) * | 2015-12-31 | 2018-12-21 | 先健科技(深圳)有限公司 | Occluder for left auricle |
| CN106923883B (en) * | 2015-12-31 | 2019-09-03 | 先健科技(深圳)有限公司 | Occluder for left auricle |
| CN106994030B (en) * | 2016-06-15 | 2020-03-10 | 先健科技(深圳)有限公司 | Left auricle plugging device |
| CN106510788A (en) * | 2016-12-12 | 2017-03-22 | 上海心玮医疗科技有限公司 | Left atrial appendage occlusion device |
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