CN106349145B - 一种制备促智药物(s)-奥拉西坦的方法 - Google Patents
一种制备促智药物(s)-奥拉西坦的方法 Download PDFInfo
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- CN106349145B CN106349145B CN201610875256.6A CN201610875256A CN106349145B CN 106349145 B CN106349145 B CN 106349145B CN 201610875256 A CN201610875256 A CN 201610875256A CN 106349145 B CN106349145 B CN 106349145B
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- 0 C[C@@](CC1)CN(C*)C1=O Chemical compound C[C@@](CC1)CN(C*)C1=O 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N O=C1NCCC1 Chemical compound O=C1NCCC1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610875256.6A CN106349145B (zh) | 2016-09-30 | 2016-09-30 | 一种制备促智药物(s)-奥拉西坦的方法 |
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CN201610875256.6A CN106349145B (zh) | 2016-09-30 | 2016-09-30 | 一种制备促智药物(s)-奥拉西坦的方法 |
Publications (2)
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CN106349145A CN106349145A (zh) | 2017-01-25 |
CN106349145B true CN106349145B (zh) | 2018-11-20 |
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Families Citing this family (2)
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CN108147987A (zh) * | 2017-12-24 | 2018-06-12 | 中山市小榄企业服务有限公司 | 一种合成α-吡咯烷酮乙酰胺的方法 |
CN110563711A (zh) * | 2019-09-17 | 2019-12-13 | 北京振东光明药物研究院有限公司 | 阿法替尼降解杂质化合物、其制备方法及应用 |
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CN102603604B (zh) * | 2011-01-21 | 2014-01-22 | 重庆润泽医药有限公司 | (s)-4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法 |
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2016
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C06 | Publication | ||
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SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Xu Min Inventor after: Fu Cheng Inventor after: Wang Chuanxiu Inventor before: Wang Chuanxiu |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20181015 Address after: 261500 Gaomi City people's Hospital, 77 Fu Street West, Gaomi City Town, Weifang, Shandong Applicant after: Xu Min Applicant after: Fu Cheng Address before: 266109 office 825, building 1, 205 Zhengyang Road, Chengyang District, Qingdao, Shandong. Applicant before: QINGDAO YUNTIAN BIOTECHNOLOGY Co.,Ltd. |
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GR01 | Patent grant | ||
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20221214 Address after: No. 302, Unit 3, Building 13, Second Wolong Garden, Shizhong District, Jinan, Shandong 250000 Patentee after: Wang Zhengqiang Address before: 261500 Gaomi City people's Hospital, 77 Fu Street West, Gaomi City Town, Weifang, Shandong Patentee before: Xu Min Patentee before: Fu Cheng |