CN106344849A - External stone-resolving formula for treating gout - Google Patents
External stone-resolving formula for treating gout Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention relates to an external stone-resolving formula for treating gout. An external preparation in the external stone-resolving formula is made of, by weight, 5-20 parts of raw rhubarb, 20-35 parts of natrii sulfas, 5-15 parts of olibanum, 5-15 parts of myrrh, 5-15 parts of herba siegesbeckiae, 5-15 parts of spina gleditsiae and 5-15 parts of rhizoma smilacis glabrae. The external stone-resolving formula has the advantages that the external preparation for treating gouty arthritis comprises scientific components, Chinese herbal medicines are externally used, the gouty arthritis can be treated under combined synergistic effects of the various medicines, the external preparation is nontoxic and harmless to human bodies, free of decoction, easy and convenient to use and low in cost and can directly act on lesions, the internal disease can be treated externally, and obvious curative effects can be realized.
Description
Technical field
The invention belongs to the field of Chinese medicines, the gout lithodialysis side of more particularly, to a kind of external.
Background technology
The traditional Chinese medical science thinks, gout " arthromyodynia " category, similar with the disease such as " severe and migratory arthralgia ", " severe and migratory arthralgia " time.The traditional Chinese medical science " gout "
Name start from " Further Discourses on the Properties of Things gout ".The traditional Chinese medical science sees " Ling Shu Miraculous Pivot or Divine Axis harmful wind " piece earliest to the understanding of gout etiology and pathogenesis: " this all
Taste and hindered in dampness, be hidden among blood vessels, between boundary between muscles, stay for a long time and do not go, if falling down, stagnant blood is interior and do not go；Finally
So intemperance of emotions, diet is uncomfortable, and frequently, space between skin and muscles closes and obstructed cold temperature.It is opened and trembles with fear to the wind, then vim and vigour condense, and attack with old pathogen phase,
It is then arthralgia due to cold.It has heat then sweating, sweating then wind-engaging.Though not meeting harmful wind pathogen, here must there is disease on the basis of latent pathogen induced by a new affection." "Nei Jing" points out again
" so-called numbness person, respectively so that at that time, reinfection is in the wet gas of wind and cold ".ZHU Dan-xi point out in " Further Discourses on the Properties of Things gout " " gout person,
Extremity hundred section walks pain, and in book, the severe and migratory arthralgia wind card of meaning is ..., and greatly rate is heated because of blood, self-boiling, thereafter or relate to cold water,
Or vertical wetland, or pectinid takes and works as wind coolly or sleeping, cold and cool outer fight, warm blood must be trembled with fear, dirty solidifying puckery so having a pain, night then pain very, OK
In the moon." also indicate that " this is by blood for oncotic arthralgia of limbs, hesitant pulse number person ", " cloudy point of cold-damp heresy numbness is then changed heat long and attacked pain " etc., its
Afterwards doctor all ancestors its say.Bright Zhang Jingyue is sayed in " Jing Yue's complete work migratory arthralgia " again: " migratory arthralgia one is demonstrate,proved, i.e. the so-called gout of moderns
"；It thinks in " Jing Yue's complete work tinea pedis " " be outward that YIN-cold water is wet, modern damp attacks people's flesh tendon, interior by delicious food mistake usually
Degree, burnt under moist chamber, cold strongly fragrant with damp phase knot and change heat, stop the red and swollen hectic fever of skin ... diseased region, long then osteomyelitis ".Zhang Jing
Gout is classified as migratory arthralgia by high mountain, and think its onset because interior by lower Jiao of excessive, the wet plug of delicious food usually, outward people's skin and flesh muscle is attacked by damp
Caused by arteries and veins.Stupid more the explicitly pointing out in " the logical gout of Zhang Shi doctor " of a stone clearly " is demonstrate,proved by gout one.The power and prestige of " spirit is scratched " meaning, " element
Ask " numbness of meaning, the severe and migratory arthralgia of " goldsmith " name, later age is renamed and is said severe and migratory arthralgia, how to be attacked in an opponent's defence in meridians, coagulation of QI-blood by wind and cold dampness
Caused ".Clear YU Jia-yan is said in " Principle and Prohibition for Medical profession ": " one severe and migratory arthralgia wind of gout, arthralgia aggravated by cold actually ".Clear Lin Peiqin
" class disease controls sanction " then says " gout, arthralgia aggravated by cold one disease ... ... is just divided, and then changes heat long to pain, to Night Watch play " because wind and cold damp-stagnancy numbness is cloudy.
" Elementary Medicine " is said: " many endogenous causes of ill blood deficiency has fire for gout, the timid thin person of shape；Shape fertilizer brave person, many exopathogenic factors rheumatism gives birth to expectorant；Followed with it and go through time
Body, day severe and migratory arthralgia, very sting as tiger, bitterly must night notably, blood is in the moon ".Gong Tingxian points out " an acute pain in " ten thousand cause of disease spring " again
Wind limb pain person, pain belongs to fire, swollen belongs to wet ... thus people's polyphagia of fat meat and fine grain decoct fry, process fight, wine meat, hot thing steams internal organs, so suffering from
Gout, malignant boil carbuncle person is most ".Can be seen that the etiology and pathogenesis to gout for the ancient medicine from above-mentioned enumerating document, with the modern times
Medical science viewpoint has necessarily approximate part.
Clinically generally to alleviate acute arthritises outbreak, prevent arthritis from recurring, correct hyperuricemia, prevent because of urine
The complication that hydrochlorate is deposited on caused by kidney, joint etc. is main purpose.During acute arthritises outbreak, mainly eliminate urate
The inflammation of induction, using Colchicine, nonsteroidal anti-inflammatory drug, and with sodium bicarbonate alkalized urine, promotes uric acid to dissolve.In disease
Disease alleviation and prevent gout recurrence aspect, with uric acid resistings such as allopurinol, Narcaricin Mite, Probenecid, have certain curative effect.To the greatest extent
Pipe western medical treatment can relief of symptoms, but toxic and side effects are larger.Because disease condition has gradually ascendant trend in recent years, cause many
Scholar increasingly payes attention to the Therapy study of gout.
Its primary treatments has medicine to take orally and diseased region operative treatment at present.
1st, endo-medicine treatment: the general oral medicine adopting such as: indometacin, Colchicine, allopurinol, Narcaricin Mite
Deng.Endo-medicine treatment is more convenient, 3～7 days can quick symptom relief.But there is the therapeutic effect to focus in endo-medicine
Not notable, easily human body is had side effects, cause the problem of the functional lesions such as liver, kidney, stomach.
2nd, operative treatment: be primarily directed to the patient of joint deformity, tophuses, fistulization, take and carry out in affected area
The method of excision, but operative treatment can not thoroughly be eradicated to gouty arthritises.This kind of Therapeutic Method patient is painful big, operation disease
Become position and often delay difficult healing, there is certain risk, and medical expense is high, easily recur.
Content of the invention
In order to mitigate patient with gout clinical symptoms and reduce recurrence, reduce serum uric acid level, the purpose of the present invention is basis
Tcm theory, provides a kind of gout lithodialysis side of external, the mesh realized alleviating pain using the compatibility of Chinese medicine and reduce recurrence
's.
A kind of gout lithodialysis side of external, according to deal meter, is made up of following raw material medicaments: Radix Et Rhizoma Rhei 5 to 20, Natrii Sulfas 20 to
35, Olibanum 5 to 15, Myrrha 5 to 15, Herba Siegesbeckiae 5 to 15, Spina Gleditsiae 5 to 15, Rhizoma Smilacis Glabrae 5 to 15.
A kind of gout lithodialysis side of external, according to deal meter, is made up of following raw material medicaments: Radix Et Rhizoma Rhei 10, Natrii Sulfas 30, Olibanum
10, Myrrha 10, Herba Siegesbeckiae 10, Spina Gleditsiae 10, Rhizoma Smilacis Glabrae 10.
The present invention can make multiple dosage forms, such as tincture, liniment, spray or patch etc.；For affected part outside directly, one day 3
～5 times, affected part is put in appropriate painting every time on the skin, suitably massages, and 10 days is 1 course for the treatment of, can suitably increase and decrease the course for the treatment of according to the state of an illness.The present invention is outer
With agent, forbid to take orally.
The pharmacological property of medical material of the present invention and effect:
Radix Et Rhizoma Rhei: cold in nature, bitter in the mouth；Return stomach, large intestine, liver, spleen channel；Major function is stasis removing, relieving constipation by purgation, real for gastrointestinal
Heat is stagnant, constipation；
Natrii Sulfas: salty in the mouth, hardship, cold in nature；Return stomach, large intestine channel；Effect is relieving constipation by purgation, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat；Cure mainly for reality
Heat is stagnant, abdominal distention distending pain, constipation due to dry stool, and acute appendicitis swells and ache；External treatment acute mastitis, swelling and pain of hemorrhoid；
Olibanum: warm in nature, acrid in the mouth, hardship；GUIXIN, liver, spleen channel；There is blood-activating and qi-promoting pain relieving and the effect of detumescence and promoting granulation；
Myrrha: acrid in the mouth, hardship, mild-natured；GUIXIN, liver, spleen channel；There is scattered stasis pain and the effect of detumescence and promoting granulation；
Herba Siegesbeckiae: property is pungent, bitter, cold in nature；Return liver and kidney channel；There is wind-damp dispelling, pain relieving, for treating Liver and kidney pathogenic wind, extremity
Paralysis, osteodynia knee joint are weak, all skin ulcers of rheumatism；
Spina Gleditsiae: acrid in the mouth, warm in nature；Return liver, stomach；Effect is detumescence poison holding, evacuation of pus, parasite killing；Cure mainly for carbuncle from the beginning of or pus
Become not burst, external treatment scabies leprosy；
Rhizoma Smilacis Glabrae: sweet in the mouth, light, mild-natured；Return liver, stomach；Effect is removing toxic substances, dehumidifying, easing joint movement；Cure mainly syphilis and mercurialism institute
The limbs contracture causing, bones and muscles pain；Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies.
Radix Et Rhizoma Rhei bitter cold in prescription of the present invention, main attack dissipates excess pathogen and stagnates, and is apt to walk and alters and power is violent, can blood circulation promoting and blood stasis dispelling,
Removing obstruction in the collateral to relieve pain, again can clearing heat, releasing toxin, removing swelling, for monarch drug in side.Natrii Sulfas are salty-cold, with heat-clearing and toxic substances removing, reducing swelling and alleviating pain, hard masses softening and resolving
For main effect, this is ministerial drug.Olibanum pungent-warm, blood-activating and qi-promoting, reducing swelling and alleviating pain power strong, do not have the property of medicine to work hard, be good at promoting blood circulation and detumescence and stop
Bitterly, two medicine synergism, reducing swelling and alleviating pain is higher；Rhizoma Smilacis Glabrae is sweet flat, and with removing dampness and detoxicating for effect, effectively clear away the dampness and heat poison heresy, and
Easing joint movement, the only pain at podomere pass；Herba Siegesbeckiae work hard cold, can heat-clearing and toxic substances removing wind-damp dispelling, kind swell and ache numbness except limbs, on
Stating four tastes is adjuvant drug altogether.Spina Gleditsiae pungent-warm, kind dredging collateral is walked to alter, Tuoli eliminating evil, for making medicine.Side amounts to heat-clearing and toxic substances removing, detumescence entirely
The effect of pain relieving.
The pharmacology of prescription of the present invention and effect are: this compositions is mutually coordinated, collective effect, are removed with reaching heat clearing away
Wet, blood circulation promoting and blood stasis dispelling, the effect of mass dissipating and swelling eliminating pain relieving.
Specific embodiment
The external preparation that gouty arthritises treated by prescription of the present invention passes through scientific composition, using Chinese herbal medicine outside
With, using the comprehensive co-action for treating gout arthritis of various medicines, nontoxic to human body, need not decoct, interior disease is outer
Control, through lesion, feature easy to use, cheap, evident in efficacy.
Specific embodiment is as follows:
Embodiment 1
According to deal meter, weigh Radix Et Rhizoma Rhei 10, Natrii Sulfas 30, Olibanum 10, Myrrha 10, Herba Siegesbeckiae 10, Spina Gleditsiae 10, Rhizoma Smilacis Glabrae 10,
By above-mentioned raw materials medicine, routinely preparation technology makes tincture, liniment, spray or patch, is then directly used for affected part.
The concrete preparation process of such as liniment is: said herbal medicine is ground into the smalls of 100 mesh, the second directly Jia 60%
Alcohol dissolves, and stirs, and filters and obtains final product, every 100 grams of medical materials can be made into 1000 milliliters about of solution after soaking one week about.
Usage and dosage: 3～5 times on the one, affected part is put in appropriate painting every time on the skin, suitably massages, and 10 days is 1 course for the treatment of, can according to the state of an illness
The suitably increase and decrease course for the treatment of.
It is to be that therefore, inventor is not to tincture, spray or patch using existing conventional fabrication process due to pharmacy procedure
Preparation method is described in detail.
Points for attention: a, alcohol intolerance person use with caution, forbid to take orally.B, anemia of pregnant woman use with caution, and skin injury person disables.If c has heavy
Shallow lake please use after shaking up.
Embodiment 2
According to deal meter, according to deal meter, Radix Et Rhizoma Rhei 15, Natrii Sulfas 35, Olibanum 15, Myrrha 15, Herba Siegesbeckiae 15, Spina Gleditsiae 15, soil
Poria 15, by above-mentioned raw materials medicine, routinely preparation technology makes tincture, liniment, spray or patch, is then directly used for affected part and is
Can.
Embodiment 3
According to deal meter, it is made up of following raw material medicaments: Radix Et Rhizoma Rhei 5, Natrii Sulfas 20, Olibanum 5, Myrrha 5, Herba Siegesbeckiae 5, Spina Gleditsiae 5, soil
Poria 5, by above-mentioned raw materials medicine, routinely preparation technology makes tincture, liniment, spray or patch, is then directly used for affected part and is
Can.
Embodiment 4
According to deal meter, it is made up of following raw material medicaments: Radix Et Rhizoma Rhei 10, Natrii Sulfas 30, Olibanum 10, Myrrha 10, Herba Siegesbeckiae 10, Spina Gleditsiae
10, Rhizoma Smilacis Glabrae 10, by above-mentioned raw materials medicine, routinely preparation technology makes tincture, liniment, spray or patch, is then directly used for suffering from
Locate.
Model case one
Lee, man, 65 years old, repeatedly right sufficient Metatarsophalangeal joint, right ankle swell and ache the several years, closely gout in periarticular over the past half year
Stone, is gout in hospital diagnosis, and it is ineffective to take the Western medicine a few days, upon somebody's introduction using this medicament January after, arthralgia symptom
Disappear, after March, tophuses reduce.
Model case two
Huang, man, 71 years old, in double knee joint discontinuity more than 10 years of pain, engender tophuses over nearly 2 years, nearly first quarter moon both legs can not be stretched
Directly, activity has obstacle.Once sought medical advice everywhere diagnosis and treatment, double knee joints are not but felt any better all the time, are diagnosed as gouty arthritises.
Treat five courses for the treatment of through patch of the present invention, patient's double knee joint swelling, pain substantially mitigate, and bend and stretch function relatively
Before be obviously improved.After the medicine of eight courses for the treatment of, double knee joint swells and ache disappearance, and tophuses are gradually reduced, and patient activity is freely.Follow-up
So far there is not recurrence sign.
Model case three
Jiang, man, 45 years old, ictal biped Metatarsophalangeal joint pain 2 years, locally engender tophuses, in hospital's doctor trained in Western medicine
Diagnosis and treatment take Western medicine several weeks ineffective fruit, and after being introduced using medicament of the present invention more than March, symptom disappears.
Model case four
Wang, man, 66 years old, gouty arthritises patient for many years, biped Metatarsophalangeal joint pain occurred, gradually double knee joints before 10 years
Arthralgia, recurrent exerbation.There is joint red and swollen heat pain early stage, and late period double gonatagra stones and formed, with dysfunction.Through
Patch of the present invention treats April, and patient's double knee joint swells and ache disappearances, tophuses minimizing, clinical recovery, and patient activity is freely.Follow-up
So far there is not recurrence sign.
Claims (3)
1. a kind of gout lithodialysis side of external it is characterised in that: according to deal meter, be made up of following raw material medicaments: Radix Et Rhizoma Rhei 5 to
20, Natrii Sulfas 20 to 35, Olibanum 5 to 15, Myrrha 5 to 15, Herba Siegesbeckiae 5 to 15, Spina Gleditsiae 5 to 15, Rhizoma Smilacis Glabrae 5 to 15.
2. as claimed in claim 1 a kind of gout lithodialysis side of external it is characterised in that according to deal meter, by following raw materials
Medicine is made: Radix Et Rhizoma Rhei 10, Natrii Sulfas 30, Olibanum 10, Myrrha 10, Herba Siegesbeckiae 10, Spina Gleditsiae 10, Rhizoma Smilacis Glabrae 10.
3. as claimed in claim 1 a kind of gout lithodialysis side of external it is characterised in that described gout lithodialysis side is using conventional
Technique makes tincture, liniment, spray or patch.
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| CN201610827668.2A CN106344849A (en) | 2016-09-18 | 2016-09-18 | External stone-resolving formula for treating gout |
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| CN201610827668.2A CN106344849A (en) | 2016-09-18 | 2016-09-18 | External stone-resolving formula for treating gout |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113384656A (en) * | 2021-06-17 | 2021-09-14 | 云南省中医医院(云南中医药大学第一附属医院) | Traditional Chinese medicine external fossil cream for treating subcutaneous tophus and preparation method thereof |
| CN111491625B (en) * | 2017-12-15 | 2023-12-01 | 贺亮 | Dissolving monosodium urate for treating gout |
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| CN101474359A (en) * | 2009-01-20 | 2009-07-08 | 贵州苗康堂生物科技有限公司 | Miao medicine plaster for treating gout |
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2016
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101474359A (en) * | 2009-01-20 | 2009-07-08 | 贵州苗康堂生物科技有限公司 | Miao medicine plaster for treating gout |
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| Title |
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| 虞佩兰等主编: "《实用中医儿科手册》", 31 August 1980, 湖南科学技术出版社 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111491625B (en) * | 2017-12-15 | 2023-12-01 | 贺亮 | Dissolving monosodium urate for treating gout |
| CN113384656A (en) * | 2021-06-17 | 2021-09-14 | 云南省中医医院(云南中医药大学第一附属医院) | Traditional Chinese medicine external fossil cream for treating subcutaneous tophus and preparation method thereof |
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Application publication date: 20170125 |