CN106344748A - Rhinitis powder and preparation method thereof - Google Patents

Rhinitis powder and preparation method thereof Download PDF

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Publication number
CN106344748A
CN106344748A CN201610971155.9A CN201610971155A CN106344748A CN 106344748 A CN106344748 A CN 106344748A CN 201610971155 A CN201610971155 A CN 201610971155A CN 106344748 A CN106344748 A CN 106344748A
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rhinitis
powder
preparation
nasal
nasal cavity
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胡德法
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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Abstract

The invention relates to rhinitis powder and belongs to the technical field of traditional Chinese medicine preparations. Sole horn powder, musk, borneol, camphor, magnolia flower, litsea cubeba, rhizoma arisaematis, astragalus membranaceus, areca-nut and ligusticum chuanxiong hort at a certain ratio are prepared into an external application powder agent. The drug powder can be easily blown into nasal cavity, can reach nasion and fully adhere to the inner wall of the nasal cavity, so that the treatment for various nasal cavity diseases, including, nasosinusitis, prosopantritis, nasal polyp, atrophic rhinitis nasal mucosa, acute rhinitis, chronic rhinitis, anaphylactic rhinitis, and the like, can be realized, the effect is obvious and the cure rate is higher.

Description

Rhinitis powder and preparation method thereof
Technical field
The invention belongs to Chinese medicine technical field, it is specifically related to a kind of rhinitis powder；Meanwhile, the invention still further relates to a kind of The preparation method of rhinitis powder.
Background technology
Rhinitis is nasal cavity inflammatory disease, is virus, antibacterial, allergen, various physical and chemical factor and some systemic diseases The inflammation of the bronchia mucosal causing.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hypertrophy, atrophy or bad Wait indefinitely.Failing to obtaining timely and preferable treatment, easily cause that sb.'s illness took a turn for the worse, and cause a series of serious complication (for example: sinusitis, acute pharyngitises, otitis media, nasal polyp, tracheitiies and bronchitis etc.).
The general symptom of rhinitis is as follows: the scorching hot pain of rhinorrhea, nasal obstruction, rhinocnesmus, ozena, sneeze, nasal cavity, snores, easily Flu, headache and local pain, hyposmia, dyspnea, dizzy feeling of fullness in the head dim eyesight, it is difficult to sleep, night dreaminess, Yi Xing, is remembered Recall power to go down.During cleaning face, touching the bridge of the nose has pain, and severe patient even aches cause and sheds tears.
At present, treat this sick medicine and mostly can only control symptom temporarily, cure rate is low, and treatment time is long, treatment cost With height.
Content of the invention
The present invention provides a kind of rhinitis powder, and to rhinitis and other disease effect substantially, curative effect is fast, short treating period, and cure rate is higher.
For achieving the above object, the rhinitis powder of the present invention, is formed by the preparation of raw material of following components by weight percent:
Further, this rhinitis powder, is formed by the preparation of raw material of following components by weight percent:
Present invention simultaneously relates to a kind of preparation method of rhinitis powder, the method comprises the steps:
A, each raw material is mixed by weight ratio after, be placed on old china device interior sealing store；
B, by after sealed storage raw material take out, process Powdered medicated powder；
C, will medicated powder load air-tight bottle in standby.
Further, the storage temperature in step a is 15 degree～35 degree, and storage time is 2.5 months -3.5 months.
Further, the granularity of step b Chinese medicine powder is 800---1200 mesh.
Further, the granularity of step b Chinese medicine powder is 1100 mesh.
Further, in step c, every bottle of weight is 2.9-3.1g.
In technical scheme:
Solely horn powder namely Cornu rhinocerotis powder, are to be made with Cornu rhinocerotis, Cornu rhinocerotis, i.e. Cornu rhinocerotiss, be Rhinocerotidae animal Rhinoceros unicornis, The angle of rhinoceros sondaicuses, rhinoceros sumatrensis etc., its nature and flavor acid is salty, trembles with fear, is antipyretic, heat removing and blood cooling medicine, function heat clearing away, removing heat from blood, arresting convulsion, solution Poison.
Moschus has removing blood stasis to become silted up effect.
Borneolum Syntheticum, also known as piece brain, Fructus Citri tangerinae piece, Blumeae preparatum Tabellae, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing Deng, be by Compositae Herba Blumeae Balsamiferae stem and leaf or canella Borneolum Syntheticum Camphor tree branch and leaf through steam distillation and recrystallization and obtain, also useful Lignum Pini Nodi Oil obtains through a series of chemical method techniques.
Camphora have functions that orifice opening, qi stagnation removing, ward off foul, killing parasites for relieving itching, reducing swelling and alleviating pain its can be used for excess syndrome of stroke coma, For conjunctival congestion and swelling pain, sore throat aphtha, it is used for sore swell and ache curative, do not hold back after bursting.
The pungent scattered temperature of Flos Magnoliae is led to, fragrance is walked to alter, up head, kind clearing the nasal passage, because controlling nasosinusitis headache key medicine, as long as simultaneously suitable When compatibility, its partially cold partial heat all can be applied
Grey son, collection, from herbaceous plant Fructus Xanthii fruit, has the effects such as alleviate pain.
Rhizoma Arisaematiss, with spherical tuber hyoscine, have the function of expelling wind for relieving convulsion, dissipating phlegm and resolving masses.
The Radix Astragali has enhancing human body immunity function, liver protection, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial and makees With.
Semen Arecae has the effect of " sending down the abnormal ascending QI row is stagnant for parasite killing, removing mass, row water dampness ".
The pungent scattered temperature of Rhizoma Chuanxiong is led to, energy dispelling wind and removing obstruction in the collateral pain relieving, again can dispelling the wind and dampness pathogens arthralgia pain.
As above ingredient, complements each other, so that the medicine made, when being blown into nasal cavity or sucking nasal cavity, allows medicine Powder reaches at the nasion, fully sticks to nasal cavity inwall, and nose has the sensations such as certain fiber crops are swollen, cry, after five minutes again medicated powder even Blow out together with nasal mucus, nose can be made penetrating.Typically early, late and breakfast, lunch and dinner are each once, continuous three days, can substantially recover after ten days Normally, normal are recovered to allergic rhinitises and color sinusitis about two months.Its using method is simple, and short treating period, curative effect are fast, healing Rate is high.
Specific embodiment
With reference to specific embodiment, embodiment, present invention is described in detail:
Embodiment 1
The rhinitis powder that the present embodiment is related to, including the ingredient of following weight proportion:
Solely 1 part of horn powder, 1 part of Moschus, 10 parts of Borneolum Syntheticum, 10 parts of Camphora, 30 parts of Flos Magnoliae, grey sub 25 parts, 25 parts of Rhizoma Arisaematiss, 50 parts of the Radix Astragali, 30 parts of Semen Arecae, 25 parts of Rhizoma Chuanxiong.
By the ingredient of as above parts by weight, after mix homogeneously, it is placed in porcelain container, after sealing 3 months, take out, It is processed into powder, after becoming rhinitis powder, load standby in air-tight bottle.
When using, rhinitis powder is sucked nasal cavity by patient, allows medicated powder reach at the nasion, fully sticks to nasal cavity inwall, Again medicated powder is blown out together with nasal mucus after five minutes.Typically early, late and breakfast, lunch and dinner are each once, continuous three days, can base after ten days This recovery is normal, recovers normal to allergic rhinitises and color sinusitis about two months.
Embodiment 2
The rhinitis powder that the present embodiment is related to, it is substantially the same manner as Example 1, and difference is that rhinitis powder includes weighing as follows The ingredient of amount proportioning: solely 1 part of horn powder, 1 part of Moschus, 8 parts of Borneolum Syntheticum, 8 parts of Camphora, 25 parts of Flos Magnoliae, grey sub 20 part, day south 29 parts of star, 45 parts of the Radix Astragali, 40 parts of Semen Arecae, 30 parts of Rhizoma Chuanxiong.
Embodiment 3
The rhinitis powder that the present embodiment is related to, it is substantially the same manner as Example 1, and difference is that compositionss include weighing as follows The ingredient of amount proportioning: solely 1.5 parts of horn powder, 1.5 parts of Moschus, 12 parts of Borneolum Syntheticum, 12 parts of Camphora, 35 parts of Flos Magnoliae, grey sub 30 Part, 20 parts of Rhizoma Arisaematiss, 45 parts of the Radix Astragali, 30 parts of Semen Arecae, 20 parts of Rhizoma Chuanxiong.
Using rhinitis powder of the present invention, clinical 80 patients with rhinitis are tried out, wherein man 45, female 35, age 4- 78 years old, average 37 years old, the course of disease was the shortest 3 days, the longest 23 years.Symptom is mainly sinusitis, frontal sinusitis, nasal polyp, Atrophic nasal mucosas Property rhinitis, the nasal cavity class disease such as acute rhinitises, chronic rhinitiss, allergic rhinitises, such as sudden rhinocnesmus, nasal obstruction, sneeze, stream Clearly, yellow, white tears, anosmia (Wei Bu road taste), nasal obstruction because playing headache (forehead pain, headache, rear headache), can not directly inhale cool by nose The onsets such as gas are anxious, disappear fast, recurrent exerbation, and the course of disease is longer, are in pale asphyxia, substantially, nasal meatus is more for swelling inspection intranasal mucosa more Thin nasal discharge.
Patient was taken effect using five minutes, and general five days just back to normal, was within 10 days a course for the treatment of, three courses for the treatment of of severe one.Control Treating result is: cure 98, effective 1, and invalid 1, effective percentage 98%.
Criterion of therapeutical effect is as follows:
Cure: sneeze, clear nasal discharge, rhinocnesmus, nasal obstruction, sneeze, flow clear, yellow, white tears, anosmia (Wei Bu road taste), nasal obstruction Because playing headache (forehead pain, headache, rear headache) (doctor trained in Western medicine be before, during and after sinus frontalis and color hole), nose can not directly inhale cold air etc. Symptom disappears { doctor trained in Western medicine is Atrophic nasal mucosas }, and General Symptomies disappear substantially, no recur within 2 years.
Effective: Rhinitis Symptoms and General Symptomies partial disappearance or mitigation, or symptom disappear latter 1 year in recur.
Invalid: Rhinitis Symptoms and General Symptomies no change.
Treatment example 1:
Jiang keeps off, man, address: Ningjin County Xiao Wang village village Sun Jia village phoenix town, phone: 15930495443, occupation: and purchasing agent, Age 25.
Symptom: nose can't smell taste.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 3 days, no recurs for 3 years.
Treatment example 2:
Ge Runqing, man, address: Xingtai City south battalion, phone: 13231946488, occupation: student, age 13.
Symptom: rhinitis is had a headache from the crown to the back side of head, once goes examination in hospital mistake, before, during and after sinus frontalis and color hole have, Repeatedly puncture.
Treatment: rhinitis powder is sucked nasal cavity by patient, and 1 day five times, 3 courses for the treatment of are cured, and no recur for 5 years.
Treatment example 3:
Adopt bright, female, address: Xingtai City Dong Tang village, phone: 18733993996, occupation: student, age 15.
Symptom: rhinitis.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 5 days, no recurs for 3 years.
Treatment example 4:
Liu Chaoshi, man, address: Xingtai City north Soviet Union, phone: 15075920319, the age: 52 years old.
Symptom: right sinusitis, 5-6 year.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 10 days, no recurs for 3 years.
Treatment example 5:
Li Houshun, man, address: Xingtai City north battalion, age 45.
Symptom: allergic rhinitises.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 45 days, no recurs for 3 years.
Treatment example 6:
Ma Huiru, female, address: Xingtai City Dong Cun, phone: 13784906224, occupation: student, age: 14.
Symptom: sinusitis.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 15 days, no recurs for 3 years.
Treatment example 7:
Wang Ruichi, man, phone: 13131947976, occupation: student, age: 12.
Symptom: rhinitis, nasal polyp, small one and large one.
Treatment: rhinitis powder is sucked nasal cavity by patient, 1 day five times, cures for 7 days, no recurs for 3 years.

Claims (7)

1. a kind of rhinitis powder is it is characterised in that formed by the preparation of raw material of following components by weight percent:
2. rhinitis powder according to claim 1 is it is characterised in that formed by the preparation of raw material of following components by weight percent:
3. a kind of preparation method of rhinitis powder is it is characterised in that the method comprises the steps:
A, each raw material is mixed by weight ratio after, be placed on porcelain container interior sealing store；
B, by after sealed storage raw material take out, process Powdered medicated powder；
C, will medicated powder load air-tight bottle in standby.
4. rhinitis powder according to claim 3 preparation method it is characterised in that:
Storage temperature in step a is 15--35 degree, and storage time is 2.5 months -3.5 months.
5. rhinitis powder according to claim 3 preparation method it is characterised in that: the granularity of step b Chinese medicine powder is 800---1200 mesh.
6. rhinitis powder according to claim 5 preparation method it is characterised in that: the granularity of step b Chinese medicine powder be 1100 Mesh.
7. rhinitis powder according to claim 3 preparation method it is characterised in that: in step c, every bottle of weight is 2.9- 3.1g.
CN201610971155.9A 2016-11-07 2016-11-07 Rhinitis powder and preparation method thereof Pending CN106344748A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111358835A (en) * 2020-03-16 2020-07-03 宋雅慧 Formula and preparation method of rhinitis powder
CN115300555A (en) * 2022-09-20 2022-11-08 赖建文 Formula of pharmaceutical composition for treating rhinitis and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103623098A (en) * 2013-08-08 2014-03-12 马建 Externally-applied medicine for treating rhinitis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103623098A (en) * 2013-08-08 2014-03-12 马建 Externally-applied medicine for treating rhinitis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111358835A (en) * 2020-03-16 2020-07-03 宋雅慧 Formula and preparation method of rhinitis powder
CN115300555A (en) * 2022-09-20 2022-11-08 赖建文 Formula of pharmaceutical composition for treating rhinitis and preparation method thereof

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Application publication date: 20170125