CN103623267B

CN103623267B - Medication for treating allergic rhinitis

Info

Publication number: CN103623267B
Application number: CN201310645017.8A
Authority: CN
Inventors: 孙正令; 武倩
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-05
Filing date: 2013-12-05
Publication date: 2015-06-10
Anticipated expiration: 2033-12-05
Also published as: CN103623267A

Abstract

The invention discloses medication for treating allergic rhinitis. The medication is made of watermelon root and leaf, luffa root, perilla leaf, mallow root, fish otoliths, cistanche deserticola, hispid arthraxon, semen brassicae, centipede minima, folium eriobotryae, and radix angelicae. The medication can be clinically used for treating the allergic rhinitis.

Description

A kind of medicine for the treatment of of allergic rhinitis

Technical field

The invention belongs to technical field of pharmaceuticals, especially relate to a kind of medicine for the treatment of of allergic rhinitis.

Background technology

Allergic rhinitis is also known as allergic rhinitis, it is a kind of nasal mucosa chronic inflammatory disease caused by susceptible individual contact allergen, for department of otorhinolaryngology commonly encountered diseases, primary disease have pollinosis and allergic rhinitis point, show as sudden rhinocnesmus, continuously sneeze, nasal obstruction watery nasal discharge, very then hyposmia, and the course of disease is longer, fall ill irregular, bring very large misery to minimal invasive treatment and work.Treatment of allergic rhinitis commonly used single western medicine therapy in the past, but effect is not satisfactory, and the long-term practice through inventor draws, Chinese medicine is controlled allergic rhinitis and had better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, medicine to the treatment of allergic rhinitis of human non-toxic's side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of medicine uniqueness, adopt Radix et Folium Citrulli, Radix Luffae, Folium Perillae, Radix Malvae, Asteriscus Pseudosciaenae, Herba Cistanches, Herba Arthraxonis Hispidi, Semen Sinapis Albae, Herba Centipedae, Folium Eriobotryae, the Radix Angelicae Dahuricae according to certain compatibility requirement, through being processed into.

Prepare medicine of the present invention and make Radix et Folium Citrulli 40-50 part, Radix Luffae 30-40 part, Folium Perillae 20-30 part, Radix Malvae 20-30 part, Asteriscus Pseudosciaenae 10-25 part, Herba Cistanches 10-25 part, Herba Arthraxonis Hispidi 10-25 part, Semen Sinapis Albae 10-20 part, Herba Centipedae 10-20 part, Folium Eriobotryae 8-15 part, Radix Angelicae Dahuricae 8-15 part by following raw material medicaments.

Optimum weight part of medicine material medicine of the present invention is: Radix et Folium Citrulli 45 parts, Radix Luffae 35 parts, Folium Perillae 25 parts, Radix Malvae 25 parts, Asteriscus Pseudosciaenae 20 parts, Herba Cistanches 18 parts, Herba Arthraxonis Hispidi 18 parts, Semen Sinapis Albae 15 parts, Herba Centipedae 15 parts, Folium Eriobotryae 12 parts, the Radix Angelicae Dahuricae 10 parts.

The pharmacological action of medicine of the present invention is as follows:

Radix et Folium Citrulli: light, micro-hardship, cool in nature.Return large intestine channel.Clearing away heat-damp and promoting diuresis.Clinical in watery diarrhea, dysentery, scalds, the diseases such as atrophic rhinitis.

Radix Luffae: sweet, micro-hardship, cold.Promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing.Clinical in migraine, lumbago, arthromyodynia, mastitis, rhinitis, sinusitis, laryngopharynx swelling and pain, intestinal blood leeward, the diseases such as anal fistula.

Folium Perillae: acrid in the mouth, warm in nature.Return lung, spleen, stomach warp.Expelling cold and relieving exterior syndrome, dispersing lung-QI and dissipating phlegm, circulation of qi promoting and in, antiabortive, solving toxin of fish and crab.Clinical in cough with copious phlegm, nausea and vomiting, stomachache is vomited and diarrhoea, and nausea is got along well, and gestation is disliked cloudy, and ichthyophagy Eriocheir sinensis poison waits disease.

Radix Malvae: sweet, cold.Return spleen, urinary bladder channel.Clearing away heat and promoting diuresis, removing toxic substances.Clinical in edema, pyretic stranguria, leukorrhagia, acute mastitis, snake bite and insect sting etc.Heat-clearing and toxic substances removing, awaking drug.

Asteriscus Pseudosciaenae: sweet, salty, cold in nature.Return urinary bladder channel.Inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing.Clinical in stranguria caused by urinary stone, dribbling urination is not smooth, rhinitis, the diseases such as suppurative otitis media.

Herba Cistanches: sweet, salty, warm.Return kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, intestine moistening road.Cure mainly kidney yang deficiency, the sexual impotence of asthenia of essence and blood, seminal emission, nebulousurine, lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation etc.

Herba Arthraxonis Hispidi: bitter, flat.Relieving cough and relieving asthma, parasite killing detoxifies.For chronic cough asthma, hepatitis, pharyngolaryngitis, stomatitis, rhinitis, lymphadenitis, the diseases such as mastitis.

Semen Sinapis Albae: pungent, warm.Return lung, liver, spleen, stomach, heart channel.Reduce phlegm by drink, mass dissipating and swelling eliminating.Clinical in cough with asthma abundant expectoration, fullness in the chest and hypochondriac pain, numb limbs and tense tendons, arthralgia, the diseases such as multiple abscess caused by damp-phlegm.

Herba Centipedae: pungent, warm.Return lung, Liver Channel.Expelling pathogenic wind and restoring the functions of orifices in face, removing toxic substances and promoting subsidence of swelling.For rheumatic arthralgia, traumatic injury, toxic swelling, scabies.

Folium Eriobotryae: bitter, acrid, cold, nontoxic.Return lung, the heart, stomach warp.Clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, quenches the thirst.Clinical in cough due to lung-heat, deficiency of YIN consumptive disease is coughed, hemoptysis, gastric heat vomit dirty wait disease.

The Radix Angelicae Dahuricae: pungent, warm.Return lung, spleen, stomach warp.Expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, toothache, nasal obstruction, nasal sinusitis, domination of damp pathogen chronic diarrhea, women leucorrhea, ulcer sores, venom etc.

Allergic rhinitis belongs to the traditional Chinese medical science " allergic rhinitis " category, mostly shows YANG QI deficiency, often because climate change, greedy cool drink are cold or it is not enough to have a rest, excess of sexual intercourse and bringing out.Think that its cause of disease is body YANG QI deficiency, defensive enginery is low, causes exopathogen to be easy to invasion and attack.Radix et Folium Citrulli clearing away heat-damp and promoting diuresis in the present invention is monarch drug, Radix Luffae promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, Folium Perillae expelling cold and relieving exterior syndrome, dispersing lung-QI and dissipating phlegm, Radix Malvae clearing away heat and promoting diuresis, removing toxic substances, for ministerial drug, Asteriscus Pseudosciaenae inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, Herba Cistanches kidney-replenishing, benefiting essence-blood, Herba Arthraxonis Hispidi relieving cough and relieving asthma, removing toxic substances, Semen Sinapis Albae reduces phlegm by drink, mass dissipating and swelling eliminating, Herba Centipedae expelling pathogenic wind and restoring the functions of orifices in face, Folium Eriobotryae lung heat clearing, stomach function regulating, the Radix Angelicae Dahuricae dispels the wind, sensible.Find to allergic rhinitis, to there is unique curative effect, reach the object for the treatment of of allergic rhinitis through clinical practice.

Medicine of the present invention was in 2008 to 2013 the routine patients of clinical observation allergic rhinitis 85, and clinical report is as follows:

1, physical data

In 85 routine patients, in age 18-63 year, the course of disease is many at 1 month to 5 years, 35 years old mean age.

2, diagnostic criteria

" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:

With paroxysmal rhinocnesmus, continuous sneeze, nasal obstruction, the clear rare amount of nasal mucus mostly is cardinal symptom, the disease such as to itch with anodimia, ophthalmic pruritus, throat;

Onset is rapid, and the general last for several minutes of symptom is to several tens minutes, and the intermission, can the disease such as concurrent urticaria, asthma without sneeze and nasal obstruction; Often fall ill because of sensitizers such as contact pollen, flue dust, chemical gas, variation of ambient temperature also can be brought out sometimes.

3, Therapeutic Method

3.1 prescriptions: Radix et Folium Citrulli 45g, Radix Luffae 35g, Folium Perillae 25g, Radix Malvae 25g, Asteriscus Pseudosciaenae 20g, Herba Cistanches 18g, Herba Arthraxonis Hispidi 18g, Semen Sinapis Albae 15g, Herba Centipedae 15g, Folium Eriobotryae 12g, Radix Angelicae Dahuricae 10g.

3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 10 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Recovery from illness: symptom after taking medicine disappears, more than 3 months without recurrence;

Effective: during outbreak, symptom, sign alleviate, number of times reduces, but does not all disappear;

Invalid: symptom, sign slightly alleviate or the person of not being any change.

4.2 results: in 85 routine patients, clinical cure 55 example (64.7%), effective 25 examples (29.4%), invalid 5 examples (5.9%), total effective rate is 94.1%.

5, model case

5.1 Liu, man, 43 years old, over 3 years, namely cold wind flowed clear water sample nasal mucus whenever, then have a stuffy nose obstructed, sneeze is more than, hyposmia, companion fear of cold, headache and dizziness are allergic rhinitis at hospital diagnosis, once do not heal eventually with a large amount of antibiotic and the Chinese patent drugs for treatment such as BIYANKANG, ' Biyanwan ' for treating rhinitis.Pale complexion is slightly thin, micro-swollen, the mental weariness of eye born of the same parents.Concha nasalis mucosa edema, pale moistening.Tongue fur is in vain light, and deep pulse is thin and delicate.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after half a year.

5.2 Zhangs, female, 33 years old.Suffer from allergic rhinitis 2 years, often increase the weight of because of contact cold air and penetrating odor.Time medical, disease sees nasal obstruction, sneeze, a large amount of clear water nasal mucus, rhinocnesmus, lazy speech of breathing hard, time have anemophobia to be afraid of cold, check and see that tunica mucosa nasi swelling is Fructus Mori samples, color is pale purple, pale tongue, thin fur, and Sublingual venation is purple dark, weak pulse.Take medicine of the present invention, every day 1 dose, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.

Embodiment 1, a medicine for treatment of allergic rhinitis is made up of Radix et Folium Citrulli 40g, Radix Luffae 30g, Folium Perillae 20g, Radix Malvae 20g, Asteriscus Pseudosciaenae 10g, Herba Cistanches 10g, Herba Arthraxonis Hispidi 10g, Semen Sinapis Albae 10g, Herba Centipedae 10g, Folium Eriobotryae 8g, Radix Angelicae Dahuricae 8g.

Embodiment 2, a medicine for treatment of allergic rhinitis is made up of Radix et Folium Citrulli 45g, Radix Luffae 35g, Folium Perillae 25g, Radix Malvae 25g, Asteriscus Pseudosciaenae 20g, Herba Cistanches 18g, Herba Arthraxonis Hispidi 18g, Semen Sinapis Albae 15g, Herba Centipedae 15g, Folium Eriobotryae 12g, Radix Angelicae Dahuricae 10g.

Embodiment 3, a medicine for treatment of allergic rhinitis is made up of Radix et Folium Citrulli 50g, Radix Luffae 40g, Folium Perillae 30g, Radix Malvae 30g, Asteriscus Pseudosciaenae 25g, Herba Cistanches 25g, Herba Arthraxonis Hispidi 25g, Semen Sinapis Albae 20g, Herba Centipedae 20g, Folium Eriobotryae 15g, Radix Angelicae Dahuricae 15g.

Claims

1. a medicine for treatment of allergic rhinitis, is characterized in that it is made up of following raw material medicaments:

Radix et Folium Citrulli 40-50 part, Radix Luffae 30-40 part, Folium Perillae 20-30 part, Radix Malvae 20-30 part, Asteriscus Pseudosciaenae 10-25 part, Herba Cistanches 10-25 part, Herba Arthraxonis Hispidi 10-25 part, Semen Sinapis Albae 10-20 part, Herba Centipedae 10-20 part, Folium Eriobotryae 8-15 part, Radix Angelicae Dahuricae 8-15 part.

2. medicine according to claim 1, is characterized in that it is made up of following raw material medicaments:

Radix et Folium Citrulli 45 parts, Radix Luffae 35 parts, Folium Perillae 25 parts, Radix Malvae 25 parts, Asteriscus Pseudosciaenae 20 parts, Herba Cistanches 18 parts, Herba Arthraxonis Hispidi 18 parts, Semen Sinapis Albae 15 parts, Herba Centipedae 15 parts, Folium Eriobotryae 12 parts, the Radix Angelicae Dahuricae 10 parts.