CN106318687A - 一种医用多酶清洗包 - Google Patents

一种医用多酶清洗包 Download PDF

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CN106318687A
CN106318687A CN201610694649.7A CN201610694649A CN106318687A CN 106318687 A CN106318687 A CN 106318687A CN 201610694649 A CN201610694649 A CN 201610694649A CN 106318687 A CN106318687 A CN 106318687A
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王卫
周平乐
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Nanjing Jusha Display Technology Co Ltd
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Abstract

本发明公开了一种医用多酶清洗包，包括清洗剂和用于包裹清洗剂的多层清洗包，医用多酶清洗包为液态清洗包、固态清洗包或者液固混合态清洗包；清洗包的材质为水溶性膜材料，所述清洗包为单层、双层或三层水溶性薄膜的结构。且每一层薄膜遇水溶解的时间不同。本发明清洗效果好，使用方便，能去除常见医疗器械上的污物，如血渍、脂肪、蛋白等，且清洗包结构新颖，充分考虑到了临床手工清洗的实际情况。

Description

一种医用多酶清洗包
技术领域
本发明涉及一种医用多酶清洗包，属于洗涤剂领域。
背景技术
目前国内医院供应室手工清洗器械时所用的清洗剂均为液体型，一经稀释后，酶开始发挥效力，一小时内酶活已降低至原来的一半。根据国内相关规范要求，建议每四小时更换一次，此时的酶活已经大大降低。然而在实际操作中由于受到器械处理量大，器械周转快，升温速度慢等的限制，绝大多数医院还做不到四小时一换，这样一方面随着清洗剂成分的消耗使清洗力大为下降，一方面器械所带的污物易引起交差感染，使器械清洗质量得不到保障。
为了解决这一问题，本发明提供了一种医用多酶清洗包，该医用多酶清洗包不仅能有效去除、分解医疗器械上的血渍、污物，同时由于其多层的结构特点，可以在不用更换或添加清洗液的基础上提高清洗效力，省时省力；同时其中含有杀菌成分，提高清洗力的同时，有效杀灭微生物，避免二次污染。
发明内容
目的：为了克服现有技术中存在的不足，本发明提供一种医用多酶清洗包。
技术方案：为解决上述技术问题，本发明采用的技术方案为：
一种清洗剂，包括以下组分及各组分的质量份数别为：
所述低泡表面活性剂为烷醇聚醚化合物、烷基糖苷、季铵盐及其衍生物、烷基咪唑啉盐中的一种或几种。优选为烷醇聚醚化合物和季铵盐及其衍生物的混合物。
所述多酶为蛋白酶、脂肪酶、纤维素酶、淀粉酶中的一种或几种。
所述溶剂为丙二醇、丙二醇丁醚、丙二醇甲醚、乙二醇丁醚、丙二醇苯醚、甘油、水、甲氧基甲基丁醇中的一种或几种。优选为丙二醇、丙二醇丁醚、甘油和水中的一种或几种。
所述稳定剂为柠檬酸、柠檬酸钠、硼砂、硼酸、氯化镁、氯化钙、三乙醇胺、EDTA及其钠盐、碳酸氢钠、碳酸钠和亚氨基二琥珀酸四钠中的一种或几种。优选为柠檬酸、柠檬酸钠、硼砂、氯化钙、EDTA-2Na中的一种或几种。
所述清洗剂为液态或固态。
一种医用多酶清洗包，包括上述的清洗剂和用于包裹清洗剂的多层清洗包，所述医用多酶清洗包为液态清洗包、固态清洗包或者液固混合态清洗包；
所述清洗包的材质为水溶性膜材料，所述清洗包为单层、双层或三层水溶性薄膜的结构。
所述水溶性膜材料为聚乙烯醇、明胶、纤维素、淀粉、壳聚糖及其衍生物中的一种或几种。优选为聚乙烯醇及其衍生物。
所述清洗包的水溶性薄膜的水溶时间为5秒至4小时。
当清洗包为三层水溶性薄膜的结构，外层水溶性薄膜的水溶时间优选为5秒至30秒，中间层水溶性薄膜的水溶时间优选为1小时至2小时，内层水溶性薄膜的水溶时间优选为1小时至4小时。水溶性薄膜材料的水溶时间可根据薄膜厚度进行调节。
有益效果：本发明提供的医用多酶清洗包，清洗剂置于水溶性包装薄膜内，清洗包可做成含有单层、双层或三层水溶性薄膜的结构，且每一层薄膜遇水溶解的时间不同。本发明清洗效果好，使用方便，能去除常见医疗器械上的污物，如血渍、脂肪、蛋白等，且清洗包结构新颖，充分考虑到了临床手工清洗的实际情况。具有以下优点：(1)多层水溶性薄膜结构，可以在不用更换或添加清洗液的基础上提高清洗效力；(2)省时省力；(3)含杀菌成分，有效杀灭微生物，避免交叉污染；(4)结构新颖，运输、储存条件简单；(5)清洗效果佳，低温下仍保持较高清洗效果。
具体实施方式
下面结合实施例对本发明作更进一步的说明。
实施例1：
实施例1中所述的TRITONTM DF-12为美国陶氏公司的产品；TRITON BG-10是烷基糖苷类化合物，为美国陶氏的产品。
实施例1制备的医用多酶清洗包内容物为固体粉末状，可做成三层结构。外层的水溶性薄膜在40℃时溶解时间≤30秒，中间层和内层水溶性薄膜在40℃时溶解时间≤600秒。此清洗包清洗效果佳，低泡易漂洗，储存方便，同时具有较好的杀菌作用，且对304不锈钢片无任何腐蚀。
实施例2：
实施例2中所述的Pluronic PE 6200是EO、PO嵌段聚醚，为美国巴斯夫公司的产品；TRITON BG-10是烷基糖苷类化合物，为美国陶氏的产品。
实施例2制备的医用多酶清洗包内容物为液状，可做成三层结构。外层的水溶性薄膜在40℃时溶解时间15秒，中间层和内层水溶性薄膜在40℃时溶解时间2小时。此清洗包清洗效果佳，低泡易漂洗，储存方便，同时具有较好的杀菌作用，且对304不锈钢片无任何腐蚀。
以上所述仅是本发明的优选实施方式，应当指出：对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以做出若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。

Claims (10)

1.一种清洗剂，包括以下组分及各组分的质量份数别为：
低泡表面活性剂 1-20份
多酶 0.1-20份
溶剂 1-90份
稳定剂 1-80份。
2.根据权利要求1所述的清洗剂，其特征在于：所述低泡表面活性剂为烷醇聚醚化合物、烷基糖苷、季铵盐及其衍生物、烷基咪唑啉盐中的一种或几种。
3.根据权利要求1所述的清洗剂，其特征在于：所述多酶为蛋白酶、脂肪酶、纤维素酶、淀粉酶中的一种或几种。
4.根据权利要求1所述的清洗剂，其特征在于：所述溶剂为丙二醇、丙二醇丁醚、丙二醇甲醚、乙二醇丁醚、丙二醇苯醚、甘油、水、甲氧基甲基丁醇中的一种或几种。
5.根据权利要求1所述的清洗剂，其特征在于：所述稳定剂为柠檬酸、柠檬酸钠、硼砂、硼酸、氯化镁、氯化钙、三乙醇胺、EDTA及其钠盐、碳酸氢钠、碳酸钠和亚氨基二琥珀酸四钠中的一种或几种。
6.根据权利要求1所述的清洗剂，其特征在于：所述清洗剂为液态或固态。
7.一种医用多酶清洗包，其特征在于：包括权利要求1-6任一项所述的清洗剂和用于包裹清洗剂的多层清洗包，所述医用多酶清洗包为液态清洗包、固态清洗包或者液固混合态清洗包；
所述清洗包的材质为水溶性膜材料，所述清洗包为单层、双层或三层水溶性薄膜的结构。
8.根据权利要求7所述的医用多酶清洗包，其特征在于：所述水溶性膜材料为聚乙烯醇、明胶、纤维素、淀粉、壳聚糖及其衍生物中的一种或几种。
9.根据权利要求7所述的医用多酶清洗包，其特征在于：所述清洗包的水溶性薄膜的水溶时间为5秒至4小时。
10.根据权利要求7所述的医用多酶清洗包，其特征在于：当清洗包为三层水溶性薄膜的结构，外层水溶性薄膜的水溶时间为5秒至30秒，中间层水溶性薄膜的水溶时间为1小时至2小时，内层水溶性薄膜的水溶时间为1小时至4小时。
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107937156A (zh) * 2017-12-25 2018-04-20 三达奥克化学股份有限公司 医疗器械高效多酶清洗剂及其制备方法
CN108192771A (zh) * 2018-02-23 2018-06-22 南京巨鲨显示科技有限公司 一种手术器械两腔多酶凝珠及其制备方法
CN109971562A (zh) * 2019-04-23 2019-07-05 南京巨鲨显示科技有限公司 一种缓释型医用手工多酶清洗片及其制备方法
CN111567553A (zh) * 2020-06-05 2020-08-25 沈小燕 一种医疗器械用杀菌剂
CN112442425A (zh) * 2020-11-28 2021-03-05 河南省科学院化学研究所有限公司 一种低泡多酶清洗剂及其制备方法

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