CN106309914A - Traditional Chinese medicine oral liquid for treating anemia - Google Patents

Traditional Chinese medicine oral liquid for treating anemia Download PDF

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CN106309914A
CN106309914A CN201610818898.2A CN201610818898A CN106309914A CN 106309914 A CN106309914 A CN 106309914A CN 201610818898 A CN201610818898 A CN 201610818898A CN 106309914 A CN106309914 A CN 106309914A
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radix
parts
fructus
chinese medicine
oral liquid
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陈方
高志宏
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    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
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Abstract

The invention discloses a traditional Chinese medicine oral liquid for treating anemia, made from, by weight, 18-26 parts of Radix Astragali, 14-22 parts of Radix Rumicis Nepalensis, 10-15 parts of Flos Leonuri, 16-24 parts of Caulis Spatholobi, 11-17 parts of Radix Salviae Miltiorrhizae, 9-16 parts of Herba Agrimoniae, 8-14 parts of Radix Polygoni Multiflori Preparata, 5-10 parts of Fructus Ligustri Lucidi, 7-13 parts of Cordyceps, 13-21 parts of Flos Cucurbitae, 17-23 parts of Fructus Lycii, 16-24 parts of Folium Agastaches, 15-25 parts of Radix Angelicae Sinensis, 12-18 parts of Fructus Mori, 10-15 parts of Herba Ecliptae, 20-30 parts of Radix Paeoniae Alba, 17-28 parts of Fructus Jujubae, 14-22 parts of Rhizoma Polygonati, 13-19 parts of Radix Potentillae Anserinae, and 16-24 parts of Radix Rehmanniae Preparata. Discrimination composing is carried out by using essence boosting and marrow replenishing, qi benefiting and yin nourishing, and blood enriching and nourishing as therapeutic principles in allusion to the pathogenesis of anemia according to the differentiation theory in traditional Chinese medicine, such that treating both symptoms and root causes is achieved, the therapeutic effect is significant, acting speed is high, the treatment course is short, it is possible to effectively promote the blood-producing function of marrow and stimulate a blood-producing system to increase human erythrocyte and hemoglobin level, and the traditional Chinese medicine oral liquid is effective in treating and preventing anemia and has significant clinical application value.

Description

A kind of Chinese medicine oral liquid treating anemia
Technical field
The present invention relates to a kind of Chinese medicine oral liquid treating anemia, belong to technical field of Chinese medicines.
Background technology
Anemia refers to erythrocyte, hemoglobin and the packed cell volume a kind of clinical common sympton less than normal value.China The erythrocyte normal value male of health adult is 400-550 ten thousand/cubic millimeter, and women is 350-500 ten thousand/cubic millimeter, blood red Albumen male is 12-16 gram of %, and women is 11-15 gram of %；Packed cell volume male is 40-50 volume %, and women is that 37-48 holds Long-pending %.Anemia person often may occur in which the tired Mental fatigue of body, dizziness and blurred vision tinnitus, pale complexion, palpitation and insomnia, numb limbs and tense tendons, and menstruation is disorderly Unrest and amenorrhea, severe patient such as even can be fainted at the sign.Clinic is generally divided into iron deficiency anemia, megaloblastic anemia, again Raw aplastic anemia and hemolytic anemia.The reason causing anemia is a lot, predominantly loses blood, erythropoiesis reduces and haemolysis etc. Three major types.At present, western medical treatment anemia, to cure the symptoms, not the disease, side effect is very big, and easily forms dependency, and Chinese traditional treatment is lean Blood, therapeutic effect is poor, takes effect slow, and the course for the treatment of is long.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, it is provided that controlling of a kind of evident in efficacy, instant effect, short treating period, treating both the principal and secondary aspects of a disease Treat the Chinese medicine oral liquid of anemia.
For achieving the above object, the technical solution used in the present invention is as follows:
A kind of Chinese medicine oral liquid treating anemia, is made up of the raw material of following weight portion: Radix Astragali 18-26, Radix Rumicis 14- 22, Flos leonuri 10-15, Caulis Spatholobi 16-24, Radix Salviae Miltiorrhizae 11-17, Herba Agrimoniae 9-16, Radix Polygoni Multiflori Preparata 8-14, Fructus Ligustri Lucidi 5-10, winter worm Summer grass 7-13, Flos Cucurbitae 13-21, Fructus Lycii 17-23, Radix agastaches 16-24, Radix Angelicae Sinensis 15-25, Fructus Mori 12-18, Herba Ecliptae 10-15, Radix Paeoniae Alba 20-30, Fructus Jujubae 17-28, Rhizoma Polygonati 14-22, Radix potentillae anserinae 13-19, Radix Rehmanniae Preparata 16-24.
Preferably, a kind of Chinese medicine oral liquid treating anemia, it is made up of the raw material of following weight portion: the Radix Astragali 22, Radix Rumicis 18, Flos leonuri 12, Caulis Spatholobi 20, Radix Salviae Miltiorrhizae 14, Herba Agrimoniae 12, Radix Polygoni Multiflori Preparata 10, Fructus Ligustri Lucidi 8, Cordyceps 11, Flos Cucurbitae 17, Fructus Lycii 19, Radix agastaches 21, Radix Angelicae Sinensis 20, Fructus Mori 16, Herba Ecliptae 13, the Radix Paeoniae Alba 25, Fructus Jujubae 24, Rhizoma Polygonati 19, Radix potentillae anserinae 17, Radix Rehmanniae Preparata 20。
The preparation method of a kind of Chinese medicine oral liquid treating anemia, comprises the following steps: in weighing by above-mentioned formulation ratio Medical material, pulverizes, and pulverized 50-80 mesh sieve, then mix homogeneously, boiling 2 times respectively, and added the water of 10-15 times amount for the first time, Decocting and extract 2-3h, second time adds the water of 5-10 times amount, decocts and extracts 1-2h, and collecting decoction filters, and being concentrated into relative density is The clear paste of 1.22-1.26, then adds 40% sodium hydroxide solution regulation pH to 8-8.5,8000-10000r/min high speed centrifugation 15-25min, takes clear liquid, and then adding 80% ethanol to clear liquid alcohol content is 50-55%, microwave treatment 20-30min, microwave power For 300-400W, ultrasonic vibration 20-30min, concussion frequency is 30-40kHZ, stands 12-24h, filters, after decompression recycling ethanol Adding appropriate syrup and Mel, add water constant volume, then with structure rubber acid-conditioning solution pH to 4.5-5, stirs evenly, and filters, fill, goes out Bacterium, gets product.
Beneficial effects of the present invention:
The present invention is theoretical according to differential diagnosis in tcm, for the pathogeny of anemia, fills out marrow with benefit essence, benefiting qi and nourishing yin, enrich blood foster Blood is the rule for the treatment of, carries out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease, and evident in efficacy, instant effect, short treating period, permissible Effectively facilitate hemopoietic function of bone marrow, stimulate hemopoietic system to improve human erythrocyte, the level of hemoglobin, to treating and preventing anemia There is good effect, there is significant clinical generalization value.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine oral liquid treating anemia, is made up of the raw material of following weight (g): the Radix Astragali 18, Radix Rumicis 14, Herba Leonuri Showy flowers of herbaceous plants 10, Caulis Spatholobi 16, Radix Salviae Miltiorrhizae 11, Herba Agrimoniae 9, Radix Polygoni Multiflori Preparata 8, Fructus Ligustri Lucidi 5, Cordyceps 7, Flos Cucurbitae 13, Fructus Lycii 17, Herba Pogostemonis Leaf 16, Radix Angelicae Sinensis 15, Fructus Mori 12, Herba Ecliptae 10, the Radix Paeoniae Alba 20, Fructus Jujubae 17, Rhizoma Polygonati 14, Radix potentillae anserinae 13, Radix Rehmanniae Preparata 16.
The preparation method of a kind of Chinese medicine oral liquid treating anemia, comprises the following steps: in weighing by above-mentioned formulation ratio Medical material, pulverizes, and pulverized 50-80 mesh sieve, then mix homogeneously, boiling 2 times respectively, and added the water of 10-15 times amount for the first time, Decocting and extract 2-3h, second time adds the water of 5-10 times amount, decocts and extracts 1-2h, and collecting decoction filters, and being concentrated into relative density is The clear paste of 1.22-1.26, then adds 40% sodium hydroxide solution regulation pH to 8-8.5,8000-10000r/min high speed centrifugation 15-25min, takes clear liquid, and then adding 80% ethanol to clear liquid alcohol content is 50-55%, microwave treatment 20-30min, microwave power For 300-400W, ultrasonic vibration 20-30min, concussion frequency is 30-40kHZ, stands 12-24h, filters, after decompression recycling ethanol Adding appropriate syrup and Mel, add water constant volume, then with structure rubber acid-conditioning solution pH to 4.5-5, stirs evenly, and filters, fill, goes out Bacterium, gets product.
Embodiment 2
A kind of Chinese medicine oral liquid treating anemia, is made up of the raw material of following weight (g): the Radix Astragali 22, Radix Rumicis 18, Herba Leonuri Showy flowers of herbaceous plants 12, Caulis Spatholobi 20, Radix Salviae Miltiorrhizae 14, Herba Agrimoniae 12, Radix Polygoni Multiflori Preparata 10, Fructus Ligustri Lucidi 8, Cordyceps 11, Flos Cucurbitae 17, Fructus Lycii 19, Radix agastaches 21, Radix Angelicae Sinensis 20, Fructus Mori 16, Herba Ecliptae 13, the Radix Paeoniae Alba 25, Fructus Jujubae 24, Rhizoma Polygonati 19, Radix potentillae anserinae 17, Radix Rehmanniae Preparata 20.
Preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine oral liquid treating anemia, is made up of the raw material of following weight (g): the Radix Astragali 26, Radix Rumicis 22, Herba Leonuri Showy flowers of herbaceous plants 15, Caulis Spatholobi 24, Radix Salviae Miltiorrhizae 17, Herba Agrimoniae 16, Radix Polygoni Multiflori Preparata 14, Fructus Ligustri Lucidi 10, Cordyceps 13, Flos Cucurbitae 21, Fructus Lycii 23, Radix agastaches 24, Radix Angelicae Sinensis 25, Fructus Mori 18, Herba Ecliptae 15, the Radix Paeoniae Alba 30, Fructus Jujubae 28, Rhizoma Polygonati 22, Radix potentillae anserinae 19, Radix Rehmanniae Preparata 24.
Preparation method is with embodiment 1.
Model case
Case 1, money, female, 33 years old, first visit on February 18 in 2014.Dizziness, weak was started without inducement before main suit half a year, Disconnected skin of lower extremity petechia, brushes teeth hemorrhage, took 20 multi-agent Chinese medicines and do not feel any better, and within 1 week, increased the weight of.After being ill without epistaxis and black Just, two is just normal, take food, without particular about food and monophagia, without color of soy sauce urine, sleep can, body weight is unchanged.Previously body is good for, without radiation Line and toxicant exposure history, without susceptibility history.Have a medical check-up: T36 DEG C, P100 beat/min, R20 beat/min, BP120/70mmHg, anemia looks, double Lower limb are dispersed in petechia, and superficial lymph knot does not touches, and sclera is the most yellow, and papillae of tongue is normal, and breastbone is without tenderness, and cardiopulmonary are without exception, liver Spleen does not touches, lower limb pneumonedema.Chemical examination: Hb 45g/L, RBC 1.5 × 1012/L, reticulocyte 0.1%, WBC 3.0 × 109/ L, classification: neutral leaflet 30%, lymph 65%, monokaryon 5%, plt 35 × 109/ L, neutrophil alkaline phosphatase (NAP) Positive rate 80%, integration 200 points, serum ferritin 210 μ g/L, serum levels of iron 170 μ g/dl, total iron binding capacity 280 μ g/dl, urine is often Rule (-), urinate Rous negative, be diagnosed as chronic aplastic anemia.Then oral liquid of the present invention is taken, after January of taking medicine, Subjective symptoms is clearly better, and complexion is moistened gradually, and after February of continuing to take medicine, malaise symptoms disappears, and physical recovery is normal.Follow up a case by regular visits to 2 Year, gun-ho.
Case 2, Liu, man, 29 years old, first visit on August 9 in 22013.Main suit is weak, pale complexion two weeks, two weeks without Reason Progressive symmetric erythrokeratodermia pale complexion, weak, it is impossible to competent, slightly dynamic then to have palpitation, breathe hard, urinate color such as strong tea, chemical examination has anemia (to have Body is not quite clear), without heating, arthralgia, alopecia, photosensitivity since morbidity, to take food and slept and be slightly worse, stool is normal.Previously body is good for, nothing The heart, liver, kidney, tuberculosis medical history, non-poisonous material contact history, medicine-less allergy history, without monophagia and habits of smoking and alcohol drinking, the eumenorrhea, in family Without similar patient.Have a medical check-up: T36.5 DEG C, P96 beat/min, R16 beat/min, Bp110/70mmHg, typically can, anemia looks, without erythra and Petechia, whole body superficial lymph knot does not touches, sclera is slight xanthochromia, and papillae of tongue is normal, thyroid (-), cardiopulmonary are without exception, and abdomen is put down Soft, liver not and, 1cm under spleen rib, sign of ascites (-), double lower limb pneumonedema.Chemical examination: blood Hb68g/L, WBC6.4 × 109/ L, N72%, L24%, M4%, it is seen that 2 normoblasts, it is seen that basophilic stippling erythrocyte, plt140 × 109/ L, reticulocyte 18%, routine urinalysis (-), urine bilirubin (-), urobilinogen strong positive, stool routine examination (-), occult blood (-), blood total bilirubin 41 μm ol/ L, bilirubin direct 5 μm ol/L, Coombs test (+).It is diagnosed as autoimmune hemolytic anemia, is then taken mouth of the present invention Taking liquid, after taking medicine 3 weeks, weak significantly alleviate, complexion is the most ruddy, and after January of continuing to take medicine, all diseases disappear entirely, and physical recovery is normal, Can normally work.Follow up a case by regular visits to 3 years, gun-ho.
Case 3, Lee, female, 31 years old, first visit on November 22 in 2013.Because of dizzy, weak 1 year, nearly February increased the weight of.Morbidity Front without any discomfort, do not take any specific drugs yet.Conscious poor physical capacity, and feel tired, unable, just there are skin and oral mucosa Hemorrhage, gum blood, easy catching a cold, urine color is normal, and nearly February adopts and substantially increases the weight of and examine.Having a medical check-up: palor, two skin of lower extremity have scattered At hemorrhage point, lymph node not enlargement all over the body, without breastbone tenderness, border of cardiac dullness expands the most to the left, has pareordia systolic murmur, Abdomen is soft, liver spleen not and, lower limb swell.Chemical examination: hemoglobin 54g/L, erythrocyte 1.54 × 1011/ L, leukocyte 1.3 × 109/ L, blood is little Plate 21 × 109/ L, net knits 0.9%.Classification: neutral dry shape 4%, leaflet 36%, lymph 52%, monokaryon 8%, counts 100 in vain Red 1 of children in evening seen from cell, after left ilium, bone marrow cell proliferation severe lowers, grain system 12%, and red is 16%, and grain is red=and 0.7: 1, grain System reduces, and with neutrality, leaflet is main, accounts for 8%, and red system is based on normoblast, and lymphocyte 70%, monokaryon 2%, full sheet is not Seeing bone marrow granule, have no megalokaryocyte, platelet is rare.It is diagnosed as aplastic anemia.Then oral liquid of the present invention is taken, Taking medicine after February, dizzy, weak be clearly better, after January of continuing to take medicine, malaise symptoms disappears, and leather is ruddy, and blood testing is normal. Follow up a case by regular visits to 2 years, gun-ho.

Claims (3)

1. the Chinese medicine oral liquid treating anemia, it is characterised in that be made up of the raw material of following weight portion: Radix Astragali 18-26, soil Radix Et Rhizoma Rhei 14-22, Flos leonuri 10-15, Caulis Spatholobi 16-24, Radix Salviae Miltiorrhizae 11-17, Herba Agrimoniae 9-16, Radix Polygoni Multiflori Preparata 8-14, Fructus Ligustri Lucidi 5- 10, Cordyceps 7-13, Flos Cucurbitae 13-21, Fructus Lycii 17-23, Radix agastaches 16-24, Radix Angelicae Sinensis 15-25, Fructus Mori 12-18, ink drought Lotus 10-15, Radix Paeoniae Alba 20-30, Fructus Jujubae 17-28, Rhizoma Polygonati 14-22, Radix potentillae anserinae 13-19, Radix Rehmanniae Preparata 16-24.
A kind of Chinese medicine oral liquid treating anemia the most according to claim 1, it is characterised in that former by following weight portion Material is made: the Radix Astragali 22, Radix Rumicis 18, Flos leonuri 12, Caulis Spatholobi 20, Radix Salviae Miltiorrhizae 14, Herba Agrimoniae 12, Radix Polygoni Multiflori Preparata 10, Fructus Ligustri Lucidi 8, Cordyceps 11, Flos Cucurbitae 17, Fructus Lycii 19, Radix agastaches 21, Radix Angelicae Sinensis 20, Fructus Mori 16, Herba Ecliptae 13, the Radix Paeoniae Alba 25, Fructus Jujubae 24, Huang Essence 19, Radix potentillae anserinae 17, Radix Rehmanniae Preparata 20.
A kind of Chinese medicine oral liquid treating anemia the most according to claim 1 and 2, it is characterised in that its preparation method bag Include following steps: weigh Chinese crude drug by above-mentioned formulation ratio, pulverize, pulverized 50-80 mesh sieve, then mix homogeneously respectively, and added Soak by water 2 times, adds the water of 10-15 times amount for the first time, decocts and extracts 2-3h, and second time adds the water of 5-10 times amount, decocts and extracts 1- 2h, collecting decoction, filters, is concentrated into the clear paste that relative density is 1.22-1.26, then add 40% sodium hydroxide solution regulation pH To 8-8.5,8000-10000r/min high speed centrifugation 15-25min, taking clear liquid, then adding 80% ethanol to clear liquid alcohol content is 50-55%, microwave treatment 20-30min, microwave power is 300-400W, ultrasonic vibration 20-30min, and concussion frequency is 30- 40kHZ, stands 12-24h, filters, adds appropriate syrup and Mel after decompression recycling ethanol, and add water constant volume, sourer with structure rubber Regulation pH value of solution, to 4.5-5, stirs evenly, and filters, fill, sterilizing, gets product.
CN201610818898.2A 2016-08-25 2016-08-25 Traditional Chinese medicine oral liquid for treating anemia Pending CN106309914A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259190A (en) * 2008-05-04 2008-09-10 北京中科仁和科技有限公司 Chinese medicine assembly for warming kidney, compensating spleen, benefitting qi and nourishing blood and preparation thereof
CN101940740A (en) * 2010-09-19 2011-01-12 张小红 Chinese medicinal preparation for treating anemia and preparation method thereof
CN105663684A (en) * 2016-02-29 2016-06-15 张坚斌 Medicine for treating aplastic anemia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101259190A (en) * 2008-05-04 2008-09-10 北京中科仁和科技有限公司 Chinese medicine assembly for warming kidney, compensating spleen, benefitting qi and nourishing blood and preparation thereof
CN101940740A (en) * 2010-09-19 2011-01-12 张小红 Chinese medicinal preparation for treating anemia and preparation method thereof
CN105663684A (en) * 2016-02-29 2016-06-15 张坚斌 Medicine for treating aplastic anemia

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Application publication date: 20170111