CN106266535A - A kind of formula for phlegm-dampness constitution and lung-moistening and throat-clearing and preparation method thereof - Google Patents

A kind of formula for phlegm-dampness constitution and lung-moistening and throat-clearing and preparation method thereof Download PDF

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Publication number
CN106266535A
CN106266535A CN201610686171.3A CN201610686171A CN106266535A CN 106266535 A CN106266535 A CN 106266535A CN 201610686171 A CN201610686171 A CN 201610686171A CN 106266535 A CN106266535 A CN 106266535A
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parts
extract
phlegm
lung
throat
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杨国清
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Shaanxi Nianqingbao Pharmaceutical Co Ltd
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Shaanxi Nianqingbao Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention discloses a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: Radix Ophiopogonis extract 26 parts, Fructus Canarii extract 15 parts, Radix Platycodonis extract 14 parts, American ginseng total saponins 13 parts, menthol 13 parts, Green Tea Polyphenols 5 10 parts.The present invention have prepare simple, with low cost, therapeutic effect is notable, cure rate is high, without poisonous side effect of medicine, use safety advantage.

Description

A kind of formula for phlegm-dampness constitution and lung-moistening and throat-clearing and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of for phlegm-dampness constitution and the formula of lung-moistening and throat-clearing and system Preparation Method.
Background technology
Chronic pharyngitis is the chronic inflammatory disease of pharyngeal mucosa, is hals,Nasen und Ohrenheilkunde commonly encountered diseases, frequently-occurring disease, has course of disease length, disease Shape stubbornness, recurrent exerbation, be difficult to cure feature, it mainly shows as pharyngeal just like foreign body sensation, gargalesthesia, burning sensation, dry sensation Or hypodynia sense, play zest hypodynia morning, or dry cough or have graininess Amylum Nelumbinis Rhizomatis sample secretions expectoration, it is intended to when feeling sick or brush teeth Vomit, pharyngeal chronic congestion during inspection, vasodilation, color kermesinus or pachymucosa, retropharyneal folliculosis.Phlegm-damp body The people of matter lacks of proper care due to qi-blood-body fluid transporting, and wet stopping gathers water, and the most poly-wet one-tenth expectorant, symptom is particularly evident seriously.
Summary of the invention
For above-mentioned, it is an object of the invention to provide a kind of for phlegm-dampness constitution and the formula of lung-moistening and throat-clearing and preparation side Method.
The present invention adopts the technical scheme that:
It is a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: Radix Ophiopogonis extract 2-6 part, Fructus Canarii extract 1-5 part, Radix Platycodonis extract 1-4 part, American ginseng total saponins 1-3 part, menthol 1-3 Part, Green Tea Polyphenols 5-10 part.
It is preferably, a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its active ingredient raw materials medicine group The optimum proportioning is become to be: Radix Ophiopogonis extract 6 parts, Fructus Canarii extract 5 parts, Radix Platycodonis extract 3.5 parts, American ginseng total saponins 2.5 parts, thin Lotus alcohol 2.5 parts, Green Tea Polyphenols 10 parts.
It is above-mentioned for phlegm-dampness constitution with the preparation method of the formula of lung-moistening and throat-clearing, it is characterised in that: take and extract above-mentioned Radix Ophiopogonis Thing, Fructus Canarii extract, Radix Platycodonis extract, American ginseng total saponins, menthol, Green Tea Polyphenols, mixing, soft by 80% ethanol system Material, 12 mesh sieves granulations, 55~60 DEG C are dried, 10 mesh sieve granulate, subpackage, packaging, and inspection gets product.
The pharmacological action of above-mentioned each effective ingredient is as follows:
Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and for dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat disappears Yearningly, dryness of the intestine constipation, pharyngeal diphtheria;
Fructus Canarii is put down, and sweet in the mouth, acid have heat-clearing and toxic substances removing, sore-throat relieving to reduce phlegm, the effect of YIN nourishing and the production of body fluid promoting;
Radix Platycodonis is put down;Bitter in the mouth, pungent, have and eliminate the phlegm, sore-throat relieving, lung qi dispersing, evacuation of pus, profit the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility Effect, cures mainly laryngopharynx swelling and pain, lung abscess vomiting pus, cough with copious phlegm, dysentery stomachache, the full hypochondriac pain of born of the same parents, aphtha of the mouth and tongue, Akamu swell and ache, urine The diseases such as the difficulty in urination;
Radix Panacis Quinquefolii has another name called Radix Panacis Quinquefolii, Radix Panacis Quinquefolii, and its main pharmacological components is total saponins, has boosting qi and nourishing yin, clearing away heat and promoting production of body fluid merit Effect, for deficiency of vital energy yin deficiency, interior-heat, cough with asthma expectorant blood, deficiency-heat be tired of tired, quench one's thirst, dryness of the mouth and throat;
Menthol have antipruritic, pain relieving, anticorrosion, stimulate, anaesthetize, refrigerant and antiinflammatory action, headache, neuralgia, pharynx, larynx can be controlled Inflammation etc.;
Green Tea Polyphenols is catechin in green tea, flavonoid, phenolic acids and the general name of anthocyan compound, and it has Stronger astriction, has significantly suppression and killing action to pathogen, virus, antiinflammatory antidiarrheal is had positive effect.
The invention have the advantage that the present invention have prepare simple, with low cost, therapeutic effect is notable, cure rate is high, without medicine Thing toxic and side effects, the advantage using safety.
Detailed description of the invention
Below embodiments of the invention are described in detail, so that advantages and features of the invention can be easier to by ability Field technique personnel understand, thus protection scope of the present invention is made apparent clear and definite defining.
Embodiment 1
It is a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: Radix Ophiopogonis extract 2 parts, Fructus Canarii extract 1 part, Radix Platycodonis extract 1 part, American ginseng total saponins 1 part, menthol 1 part, green tea tea are many 5 parts of phenol.
It is above-mentioned for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: take above-mentioned Radix Ophiopogonis extract, Fructus Canarii extracts Thing, Radix Platycodonis extract, American ginseng total saponins, menthol, Green Tea Polyphenols, mixing, by 80% ethanol soft material, 12 mesh sieve systems Grain, 55~60 DEG C are dried, 10 mesh sieve granulate, subpackage, packaging, and inspection gets product.
Embodiment 2
It is a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: Radix Ophiopogonis extract 4 parts, Fructus Canarii extract 3 parts, Radix Platycodonis extract 2.5 parts, American ginseng total saponins 2 parts, menthol 2 parts, green tea tea Polyphenol 7.5 parts.
It is above-mentioned for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: take above-mentioned Radix Ophiopogonis extract, Fructus Canarii extracts Thing, Radix Platycodonis extract, American ginseng total saponins, menthol, Green Tea Polyphenols, mixing, by 80% ethanol soft material, 12 mesh sieve systems Grain, 55~60 DEG C are dried, 10 mesh sieve granulate, subpackage, packaging, and inspection gets product.
Embodiment 3
It is a kind of for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: Radix Ophiopogonis extract 6 parts, Fructus Canarii extract 5 parts, Radix Platycodonis extract 4 parts, American ginseng total saponins 3 parts, menthol 3 parts, green tea tea are many 10 parts of phenol.
It is above-mentioned for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: take above-mentioned Radix Ophiopogonis extract, Fructus Canarii extracts Thing, Radix Platycodonis extract, American ginseng total saponins, menthol, Green Tea Polyphenols, mixing, by 80% ethanol soft material, 12 mesh sieve systems Grain, 55~60 DEG C are dried, 10 mesh sieve granulate, subpackage, packaging, and inspection gets product.
For checking the therapeutic effect of inventive formulation, spy carries out tests below method, and test method uses random packet, right According to test method(s).
Choose 100 example patients with chronic pharyngitis, and use table of random number method to be randomly divided into two groups this 100 example patient, Male 32 example in matched group 50 example, women 18 example, age 30-55 year, 38 years old mean age;In test group 50 example, male 30 example, Women 20 example, age 32-56 year, 40 years old mean age.
Diagnostic criteria is:
Cure: transference cure, pharyngeal contrafluxion is gone down, person disappears substantially folliculus;
Effective: clinical symptoms is improved, and pharyngeal mucosa hyperemia alleviates, pharynx rear wall lymph follicle reduces;
Invalid: after treatment, symptom, sign are without improving.
Give Herba Pileae Scriptae Tabellae for matched group patients with chronic pharyngitis to be treated;Give the present invention for test group to join Side's treatment, takes 3 grams day, each 1.5 grams, every day 2 times.
Observe one month, therapeutic outcome such as following table:
The effect of inventive formulation treatment chronic pharyngitis is more preferable as can be seen here.
Should be understood that this embodiment is merely to illustrate the present invention rather than limits the scope of the present invention.Furthermore, it is to be understood that After having read the content that the present invention lectures, the present invention can be made various changes or modifications by those skilled in the art, these Within the equivalent form of value falls within the protection domain that the application appended claims is limited equally.

Claims (3)

1. one kind is used for phlegm-dampness constitution and the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is made up of following ratio: wheat Winter extract 2-6 part, Fructus Canarii extract 1-5 part, Radix Platycodonis extract 1-4 part, American ginseng total saponins 1-3 part, menthol 1-3 part, Green Tea Polyphenols 5-10 part.
It is the most according to claim 1 for phlegm-dampness constitution with the formula of lung-moistening and throat-clearing, it is characterised in that: its effective ingredient is former Material medicine composition optimum proportioning is: Radix Ophiopogonis extract 6 parts, Fructus Canarii extract 5 parts, Radix Platycodonis extract 3.5 parts, American ginseng total saponins 2.5 parts, menthol 2.5 parts, Green Tea Polyphenols 10 parts.
The most according to claim 1 and 2 for phlegm-dampness constitution with the preparation method of the formula of lung-moistening and throat-clearing, its feature exists In: take above-mentioned Radix Ophiopogonis extract, Fructus Canarii extract, Radix Platycodonis extract, American ginseng total saponins, menthol, Green Tea Polyphenols, mixed Even, with 80% ethanol soft material, 12 mesh sieves granulations, 55~60 DEG C are dried, 10 mesh sieve granulate, subpackage, packaging, and inspection must become Product.
CN201610686171.3A 2016-08-18 2016-08-18 A kind of formula for phlegm-dampness constitution and lung-moistening and throat-clearing and preparation method thereof Pending CN106266535A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112274543A (en) * 2020-10-13 2021-01-29 江汉大学 Saponin polyphenol compound and preparation method and application thereof
CN114699481A (en) * 2022-04-07 2022-07-05 广州中医药大学第三附属医院(广州中医药大学第三临床医学院、广州中医药大学附属骨伤科医院、广东省中医骨伤研究院) Traditional Chinese medicine for treating swollen sore throat and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168848A (en) * 2015-09-06 2015-12-23 威海御膳坊生物科技有限公司 Compound buccal tablets prepared from lonicera japonica, Chinese olive, radix platycodi and other traditional Chinese medicines and used for clearing heat from throat
CN105770449A (en) * 2016-04-21 2016-07-20 邱林 Medicament for treating chronic pharyngitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168848A (en) * 2015-09-06 2015-12-23 威海御膳坊生物科技有限公司 Compound buccal tablets prepared from lonicera japonica, Chinese olive, radix platycodi and other traditional Chinese medicines and used for clearing heat from throat
CN105770449A (en) * 2016-04-21 2016-07-20 邱林 Medicament for treating chronic pharyngitis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112274543A (en) * 2020-10-13 2021-01-29 江汉大学 Saponin polyphenol compound and preparation method and application thereof
CN112274543B (en) * 2020-10-13 2022-04-26 江汉大学 Saponin polyphenol compound and preparation method and application thereof
CN114699481A (en) * 2022-04-07 2022-07-05 广州中医药大学第三附属医院(广州中医药大学第三临床医学院、广州中医药大学附属骨伤科医院、广东省中医骨伤研究院) Traditional Chinese medicine for treating swollen sore throat and preparation method thereof
CN114699481B (en) * 2022-04-07 2023-06-02 广州中医药大学第三附属医院(广州中医药大学第三临床医学院、广州中医药大学附属骨伤科医院、广东省中医骨伤研究院) Traditional Chinese medicine for treating sore throat and preparation method thereof

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Application publication date: 20170104