CN106266381A - A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof - Google Patents
A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof Download PDFInfo
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- CN106266381A CN106266381A CN201610664380.8A CN201610664380A CN106266381A CN 106266381 A CN106266381 A CN 106266381A CN 201610664380 A CN201610664380 A CN 201610664380A CN 106266381 A CN106266381 A CN 106266381A
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- 241000238557 Decapoda Species 0.000 title claims abstract description 80
- 238000002360 preparation method Methods 0.000 title claims abstract description 42
- 150000001875 compounds Chemical class 0.000 title claims abstract description 39
- 235000015250 liver sausages Nutrition 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title claims abstract description 10
- 239000000284 extract Substances 0.000 claims abstract description 14
- 210000000582 semen Anatomy 0.000 claims abstract description 14
- 239000000463 material Substances 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960002669 albendazole Drugs 0.000 claims abstract description 6
- 229920002261 Corn starch Polymers 0.000 claims abstract description 3
- 239000008120 corn starch Substances 0.000 claims abstract description 3
- 229940099112 cornstarch Drugs 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 3
- 230000003203 everyday effect Effects 0.000 claims description 7
- 230000037396 body weight Effects 0.000 claims description 6
- 238000012258 culturing Methods 0.000 abstract description 7
- 241001465754 Metazoa Species 0.000 abstract description 2
- 238000005070 sampling Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 239000000843 powder Substances 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 4
- 241000238631 Hexapoda Species 0.000 description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 3
- 244000046052 Phaseolus vulgaris Species 0.000 description 3
- 238000009360 aquaculture Methods 0.000 description 3
- 244000144974 aquaculture Species 0.000 description 3
- -1 compound vitamin Chemical class 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 235000013360 fish flour Nutrition 0.000 description 3
- 235000021323 fish oil Nutrition 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 241000238553 Litopenaeus vannamei Species 0.000 description 2
- 239000013049 sediment Substances 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 208000009663 Acute Necrotizing Pancreatitis Diseases 0.000 description 1
- 241000238421 Arthropoda Species 0.000 description 1
- 241001126836 Enterocytozoon Species 0.000 description 1
- 241001539217 Enterocytozoon hepatopenaei Species 0.000 description 1
- 208000000185 Localized scleroderma Diseases 0.000 description 1
- 241000243190 Microsporidia Species 0.000 description 1
- 206010027982 Morphoea Diseases 0.000 description 1
- 206010058096 Pancreatic necrosis Diseases 0.000 description 1
- 241000238550 Penaeidae Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 230000003394 haemopoietic effect Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 210000000514 hepatopancreas Anatomy 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000024241 parasitism Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Alternative & Traditional Medicine (AREA)
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Abstract
The invention discloses a kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof, by mass percentage, the raw material of described compound preparation consists of: albendazole 4.5 6.0%, Semen Arecae extract 5.0 8.0%, Cornstarch as Auxiliary Materials 86.0 90.5%.Described Semen Arecae extract is that laboratory extracts voluntarily, and through decocting in water, concentration and lyophilizing gained, 1kg Semen Arecae prepares extract 100g.The method have the advantages that the present invention to target animals safety, this compound preparation of scientifical use can kill prawn shrimp liver sausage born of the same parents worm effectively, meets the needs preventing and treating shrimp liver sausage born of the same parents worm during prawn culturing；Preparation technology is simple, easy to use, has a good application prospect.
Description
Technical field
The present invention relates to a kind of compound preparation, a kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm, with
And the using method of this compound preparation.
Background technology
Prawn belongs to Arthropoda, Crustachia, Decapoda, Penaeidae, because its delicious meat, albumen enrich, has high
Nutritive value, be the delicious food being loved by the people.Prawn in China's cultivation mainly has Litopenaeus vannamei, speckle joint right
Shrimp, Chinese prawn and japonicus etc..Litopenaeus vannamei is adaptable to salinity etc., and sea water and fresh water all can cultivate, to feedstuff egg
Require relatively low in vain, be scale and the kind of yield maximum in current China prawn culturing, account for domestic prawn culturing total amount
More than 70%.China's prawn culturing yield was at about 1,500,000 tons in recent years, cultured area about 240,000 hectares, and prawn culturing produces
Already became the pillar of the economy industry that China's aquaculture is important.
Along with developing rapidly of prawn intensive culture, the harm influence that current China prawn culturing faces is on the rise,
As guttate morphea syndrome, infectious subcutaneous and hematopoietic tissue necrosis, Fructus Persicae draw sick, the most dead disease of syndrome, Acute Hepatic pancreatic necrosis etc..Closely
Several years newfound shrimps liver sausage born of the same parents worm (Enterocytozoon hepatopenaei) in prawn, the most gradually threaten prawn
The sound development of aquaculture industry.Infecting the prawn decreased growth of shrimp liver sausage born of the same parents worm, morbidity pond occurs that Individual Size differs, seriously
Affect the cycle of forming of prawn, feedstuff return rate and market price, cause bigger economic loss to aquaculture industry.
Shrimp liver Enterocytozoon is in microsporidian, Individual Size 1 microns, and main parasitic is thin in the hepatopancrease pipe epithelium of shrimp
In born of the same parents.Its parasitism is not result in muscle nebulousurine, is also not result in the mortality of prawn, mainly causes prawn growth slow
Slowly.Detecting the prawn in morbidity pond, a certain area, individual prawn shrimp liver sausage born of the same parents' worm recall rate less than normal is almost
100%.Therefore, effectively prevention and the generation of control shrimp liver sausage born of the same parents worm and propagation have been natural trend.
Summary of the invention
The present invention purpose be to provide a kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm, and this compound recipe
The using method of preparation.
It is an object of the invention to be achieved through the following technical solutions.
A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm, by mass percentage, described compound preparation
Raw material consists of: albendazole 4.5-6.0%, Semen Arecae extract (10:1, w/w) 5.0-8.0%, Cornstarch as Auxiliary Materials 86.0-
90.5%.
Described Semen Arecae extract is that laboratory extracts voluntarily, and through decocting in water, concentration and lyophilizing gained, 1kg Semen Arecae is prepared into
To extract 100g.
The preparation method of the above-mentioned compound preparation for killing prawn shrimp liver sausage born of the same parents worm, weighs in proportion by above-mentioned raw materials,
It is sufficiently mixed uniformly, packs, put and preserve at cool place, standby.
The above-mentioned compound preparation for killing prawn shrimp liver sausage born of the same parents worm, uses for adding in prawn feed；In feedstuff
Above-mentioned compound preparation addition is 1.5-2.5%, throws something and feeds every day 2 times, and each feedstuff feeding amount is the 1.5-2.5% of shrimp body weight,
Use 6-8 days continuously.
Closer, in feedstuff, above-mentioned compound preparation addition is 2%, throws something and feeds every day 2 times, and each feeding volume is shrimp body
The 2% of weight, uses 7d continuously.
The method have the advantages that the present invention to target animals safety, this compound preparation of scientifical use can be effective
Kill prawn shrimp liver sausage born of the same parents worm, meet the needs preventing and treating shrimp liver sausage born of the same parents worm during prawn culturing；Preparation technology is simple, uses
Convenient, have a good application prospect.
Detailed description of the invention
Below in conjunction with specific embodiment, explain the present invention further.Should be understood that these embodiments are merely to illustrate the present invention
Rather than restriction the scope of the present invention.In addition, it is to be understood that after having read the content that the present invention lectures, people in the art
The present invention can be made various changes or modifications by member, and these equivalent form of values fall within the application appended claims equally and limited
Scope.
Embodiment 1
(1) being weighed by mass percentage by raw material, albendazole 6%, Semen Arecae extract (10:1, w/w) 8%, Semen Maydis form sediment
Powder 86%；It is sufficiently mixed uniformly；
(2) prawn that the compound preparation of the present invention adds to containing fish flour, bean cake powder, fish oil and compound vitamin etc. is raised
In material, addition is the 2% of prawn feed quality；
(3) from ill cultivating pool, poky prawn is selected, the long 3.5-5.0cm of body, stochastic sampling 20 tail detects,
It is defined as shrimp liver sausage born of the same parents' insect infection；
(4) with compound preparation feedstuff feeding ill prawn 75 tail (being divided into 3 parallel group) of the interpolation present invention, every day throws something and feeds
2 times, each feedstuff feeding amount is about the 2% of shrimp body weight, and throw something and feed 7d continuously；Set the compound preparation thrown something and fed without the present invention simultaneously
Feedstuff does matched group；
(5) throwing something and feeding after the compound preparation feedstuff 2d containing the present invention, ill prawn starts shelling, 7d pharmaceutical chemistry of throwing something and feeding continuously, 7d
After throw something and feed without pharmaceutical chemistry feedstuff, prawn husking yield 62.0% after 12d, and the compound preparation feedstuff always thrown something and fed without the present invention
Matched group husking yield is only 27.8%；12d stochastical sampling test group and each 20 tail prawn detection shrimp liver sausage born of the same parents worms of matched group, examination
Testing group shrimp liver sausage born of the same parents' worm positive rate is 35%, and matched group is 100%.
Embodiment 2
(1) being weighed by mass percentage by raw material, albendazole 5%, Semen Arecae extract (10:1, w/w) 6%, Semen Maydis form sediment
Powder 89%；It is sufficiently mixed uniformly；
(2) prawn that the compound preparation of the present invention adds to containing fish flour, bean cake powder, fish oil and compound vitamin etc. is raised
In material, addition is the 2% of prawn feed quality；
(3) from ill cultivating pool, poky prawn is selected, the long 3.5-5.0cm of body, stochastic sampling 20 tail detects,
It is defined as shrimp liver sausage born of the same parents' insect infection；
(4) with compound preparation feedstuff feeding ill prawn 75 tail (being divided into 3 parallel group) of the interpolation present invention, every day throws something and feeds
2 times, each feedstuff feeding amount is about the 2% of shrimp body weight, and throw something and feed 7d continuously；Set the compound preparation thrown something and fed without the present invention simultaneously
Feedstuff does matched group；
(5) throwing something and feeding after the compound preparation feedstuff 2d containing the present invention, ill prawn starts shelling, 7d pharmaceutical chemistry of throwing something and feeding continuously, 7d
After throw something and feed without pharmaceutical chemistry feedstuff, prawn husking yield 58.7% after 12d, and the compound preparation feedstuff always thrown something and fed without the present invention
Matched group husking yield is only 27.8%；12d stochastical sampling test group and each 20 tail prawn detection shrimp liver sausage born of the same parents worms of matched group, examination
Testing group shrimp liver sausage born of the same parents' worm positive rate low is 35%, and matched group is 100%.
Embodiment 3
(1) raw material is weighed by mass percentage, albendazole 4.5%, Semen Arecae extract (10:1, w/w) 5.5%, jade
Rice starch 90%；It is sufficiently mixed uniformly；
(2) prawn that the compound preparation of the present invention adds to containing fish flour, bean cake powder, fish oil and compound vitamin etc. is raised
In material, addition is the 2% of prawn feed quality；
(3) from ill cultivating pool, poky prawn is selected, the long 3.5-5.0cm of body, stochastic sampling 20 tail detects,
It is defined as shrimp liver sausage born of the same parents' insect infection；
(4) with compound preparation feedstuff feeding ill prawn 75 tail (being divided into 3 parallel group) of the interpolation present invention, every day throws something and feeds
2 times, each feedstuff feeding amount is about the 2% of shrimp body weight, and throw something and feed 7d continuously；Set the compound preparation thrown something and fed without the present invention simultaneously
Feedstuff does matched group；
(5) the compound preparation feedstuff thrown something and fed containing the present invention is after 2 days, and ill prawn starts shelling, 7d pharmaceutical chemistry of throwing something and feeding continuously, 7d
After throw something and feed without pharmaceutical chemistry feedstuff, prawn husking yield 45.7% after 12d, and the compound preparation feedstuff always thrown something and fed without the present invention
Matched group husking yield is only 27.8%；12d stochastical sampling test group and each 20 tail prawn detection shrimp liver sausage born of the same parents worms of matched group, examination
Testing group shrimp liver sausage born of the same parents' worm positive rate is 55%, and matched group is 100%.
Claims (4)
1. for killing a compound preparation for prawn shrimp liver sausage born of the same parents worm, by mass percentage, described compound preparation is former
Material consists of: albendazole 4.5-6.0%, Semen Arecae extract 5.0-8.0%, Cornstarch as Auxiliary Materials 86.0-90.5%；Described
Semen Arecae extract is that laboratory extracts voluntarily, and through decocting in water, concentration and lyophilizing gained, 1kg Semen Arecae prepares extract 100g.
2. prepare described in claim 1 for the method killing the compound preparation of prawn shrimp liver sausage born of the same parents worm for one kind, it is characterised in that:
Above-mentioned raw materials is weighed in proportion, is sufficiently mixed uniformly, packs, put and preserve at cool place, standby.
The using method of the compound preparation for killing prawn shrimp liver sausage born of the same parents worm the most according to claim 1, its feature exists
In: in feedstuff, above-mentioned compound preparation addition is 1.5-2.5%, throws something and feeds every day 2 times, and each feedstuff feeding amount is shrimp body weight
1.5-2.5%, uses 6-8 days continuously.
The using method of the compound preparation for killing prawn shrimp liver sausage born of the same parents worm the most according to claim 3, its feature exists
In: in feedstuff, above-mentioned compound preparation addition is 2%, throws something and feeds every day 2 times, and each feeding volume is the 2% of shrimp body weight, uses continuously
7d。
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610664380.8A CN106266381A (en) | 2016-08-12 | 2016-08-12 | A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610664380.8A CN106266381A (en) | 2016-08-12 | 2016-08-12 | A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof |
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| Publication Number | Publication Date |
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| CN106266381A true CN106266381A (en) | 2017-01-04 |
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| CN201610664380.8A Pending CN106266381A (en) | 2016-08-12 | 2016-08-12 | A kind of compound preparation for killing prawn shrimp liver sausage born of the same parents worm and using method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109568464A (en) * | 2019-01-17 | 2019-04-05 | 中国水产科学研究院黄海水产研究所 | It is a kind of prevent and treat shrimp crab sporidiosis composition and its application |
| CN110178973A (en) * | 2019-05-07 | 2019-08-30 | 中国科学院南海海洋研究所 | A kind of pharmaceutical chemistry additive for preventing and treating litopenaeus vannamei liver sausage born of the same parents worm |
| CN111110718A (en) * | 2020-01-03 | 2020-05-08 | 中国科学院南海海洋研究所 | A kind of prawn Enteroplasma hepatis specific killing drug and its preparation method and application |
| CN111616089A (en) * | 2020-07-13 | 2020-09-04 | 珠海市海盟水产养殖应用研发有限公司 | Method for killing EHP of penaeus vannamei boone |
| CN112957392A (en) * | 2021-03-04 | 2021-06-15 | 上海彰显渔业专业合作社 | Preparation for preventing and treating liver enterocytozoosis of prawns and shrimps as well as preparation method and application thereof |
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| CN101010075A (en) * | 2004-06-30 | 2007-08-01 | 奥加生物药业(I.P.1)有限公司 | Substances and methods for improving the health, immunity and growth of shellfish |
| CN105561099A (en) * | 2016-02-18 | 2016-05-11 | 荣成市渔业技术推广站 | Traditional Chinese medicine composition for controlling litopenaeus-vannamei enterohepatic sporozoosis and control method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109568464A (en) * | 2019-01-17 | 2019-04-05 | 中国水产科学研究院黄海水产研究所 | It is a kind of prevent and treat shrimp crab sporidiosis composition and its application |
| CN109568464B (en) * | 2019-01-17 | 2023-12-19 | 中国水产科学研究院黄海水产研究所 | Composition for preventing and treating shrimp and crab sporozoosis and application thereof |
| CN110178973A (en) * | 2019-05-07 | 2019-08-30 | 中国科学院南海海洋研究所 | A kind of pharmaceutical chemistry additive for preventing and treating litopenaeus vannamei liver sausage born of the same parents worm |
| CN111110718A (en) * | 2020-01-03 | 2020-05-08 | 中国科学院南海海洋研究所 | A kind of prawn Enteroplasma hepatis specific killing drug and its preparation method and application |
| CN111616089A (en) * | 2020-07-13 | 2020-09-04 | 珠海市海盟水产养殖应用研发有限公司 | Method for killing EHP of penaeus vannamei boone |
| CN112957392A (en) * | 2021-03-04 | 2021-06-15 | 上海彰显渔业专业合作社 | Preparation for preventing and treating liver enterocytozoosis of prawns and shrimps as well as preparation method and application thereof |
| CN112957392B (en) * | 2021-03-04 | 2022-03-08 | 上海联旺水产科技有限公司 | Preparation for preventing and treating liver enterocytozoosis of prawns and shrimps as well as preparation method and application thereof |
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Application publication date: 20170104 |