CN106266195A - Medicine for treating suppurative dactylitis by oral administration and external use - Google Patents
Medicine for treating suppurative dactylitis by oral administration and external use Download PDFInfo
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- CN106266195A CN106266195A CN201610816010.1A CN201610816010A CN106266195A CN 106266195 A CN106266195 A CN 106266195A CN 201610816010 A CN201610816010 A CN 201610816010A CN 106266195 A CN106266195 A CN 106266195A
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- 239000003814 drug Substances 0.000 title claims abstract description 44
- 229940079593 drug Drugs 0.000 title abstract description 7
- 206010064769 Dactylitis Diseases 0.000 title abstract description 4
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 7
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 7
- PLHJDBGFXBMTGZ-WEVVVXLNSA-N furazolidone Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)OCC1 PLHJDBGFXBMTGZ-WEVVVXLNSA-N 0.000 claims abstract description 7
- 229960001625 furazolidone Drugs 0.000 claims abstract description 7
- 239000011593 sulfur Substances 0.000 claims abstract description 6
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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Abstract
An oral and external medicine for treating purulent dactylitis, which belongs to the technical field of medicines and aims to solve the treatment problem of the purulent dactylitis and is characterized by being prepared by combining the following traditional Chinese medicines in parts by mass: firstly, externally applied medicine: 1 part of furazolidone tablet, 1 part of alum, 1 part of sulfur and 1 part of camphor; secondly, taking the medicine orally: 15 parts of radix rehmanniae, 12 parts of honeysuckle, 12 parts of fructus forsythiae, 12 parts of spina gleditsiae, 12 parts of radix achyranthis bidentatae and 7 parts of liquorice.
Description
Technical field
The present invention relates to the composition of medicine of a kind of therapeutic felon, particularly to the treatment combined with plurality of Chinese
Medicine, belongs to pharmaceutical technology field.
Background technology
Whitlow is to occur at referring to the subcutaneous pyogenic infection of minor details.During because infecting, whole finger abdomen height swelling
Just as snakehead, therefore named " snakehead furuncle " or " scrofula cellulitis ", because referring to that Pericarpium Arecae undertissue arranges very closely therefore in initial infection, is organized the most very
Swelling, intracavity tension force substantially increases simultaneously, sharp ache, and the blood supply of phalangette is hindered.Disease local symptom in early days is relatively
Weight;Abscess is difficult to the fluctuation of detection infected area after being formed, be the key character of this disease.
Whitlow pathogenesis: the skin of digital tip facies palmaris is intermembranous with phalanx bone many vertical shape fiber ropes,
Soft tissue is divided into many airtight loculuses, containing fatty tissue and abundant teleneuron net in chamber.When occurring to infect, pus
It is difficult to spread to surrounding, therefore swelling is the most notable.But pus cavity pressure is the highest, it is possible not only to cause the most violent pain, also
The vasa vasorum of phalangette can be oppressed, cause phalanges ischemia, downright bad healthy search.Additionally, pus is directly invaded and phalanges, also can
Cause osteomyelitis.
Whitlow clinical manifestation: at the beginning of morbidity, finger mild swelling, rubescent, twinge.Then finger swelling increases the weight of,
Skin tension substantially becomes big, and patient often feels violent jumping pain, it is difficult to sleeping.And have the symptom such as fever with aversion to cold, general malaise.Abscess
Phase, thrombosis in blood capillary, local organization tends to downright bad, whole finger abdomen can height swelling, just as snakehead.Abscess is formed
After, finger pain alleviates on the contrary, and color of the leather is white by red turn, but difficulty finds fluctuation.Skin ulceration pyorrhea, gradually heals.
The treatment of whitlow.Can give hot compress in early days, potassium permanganate soaks, 3% iodine tincture is embrocated, positive infection
Treatment can make inflammatory resolution.Before abscess is formed, available ruyi jinhuang powder, ruyi jinhuang san trouble of applying ointment or plaster refers to, but should incision and drainage as early as possible, because of infected area
It is difficult to find fluctuation, therefore according to the time infected, the incision and drainage at once when jumping pain occurs or impact is slept, it is impossible to wait.
Even if not having many puss after Qie Kaiing, to relief of symptoms, controlling inflammation, to develop in depth also be useful.Referring to nerve block fiber crops
Under liquor-saturated, referring to that stringer otch is made in side in minor details, otch far-end is less than nail groove 1/2, and near-end, less than referring to joint band, leads to for drain
Freely change dressings facility, a fusiformis leather strap can be excised in incision.Art is removed slough, thoroughly opens the fiber occurring to infect
Every, but the complete of deep layer periosteum and sheath pipe should be protected, in order to avoid inflammation diffusion.Insert photoplate drain.Art should be avoided row both sides
Aboral drainage, does not more make the lymphogranuloma inguinale shape drain otch of finger tip.The former often leaves bigger cicatrix under referring to abdomen, makes to hold thing, pinch thing
Time pain sensitivity, affect function.The latter's Ze Yin cicatrix retraction makes finger tip health search injustice, affects function and profile.Operation is
The method of relief of symptoms.
Western medicine mainly uses antibiotic therapy, and first-selected penicillin medicine intramuscular injection, allergy sufferers preferably uses cephalosporins.
Often make antibiotic can cause people's hypoimmunity.
Summary of the invention
Owing to dactylitis occurs in fingernail affected part, there is space with the junction of the human body in fingernail, these spaces become finger
Corner or spot as yet untouched by a clean-up campaign, it is easy to breed bacteria, virus cause inflammation, suppuration.Chinese medicine is thought: whitlow belongs to diseases caused by exogenous pathogenic factor
Heresy poison, the rotten bone of erosion wound, pyretic toxicity pent up, and treatment should be drawn out pus by applying a plaster to the affected part with Pesticidal and sterilizing, heat clearing away, the cooperation of the medicine oral administration and externally of dissipating blood stasis of subsiding a swelling is controlled
Treat.
According to medical analysis above, the medicine of the therapeutic felon of oral administration and externally solve the scheme that problem taked be by
The most each Chinese medicine quality part ratio combines: one, external used medicine: Furazolidone tablet 1 part, Alumen 1 part, sulfur 1 part, Camphora 1 part;
Two, endo-medicine: 15 parts of the Radix Rehmanniae, Flos Lonicerae 12 parts, Fructus Forsythiae 12 parts, Spina Gleditsiae 12 parts, Radix Achyranthis Bidentatae 12 parts, 7 parts of Radix Glycyrrhizae.
Each property of medicine effect forming Chinese medicine in the medicine of the lower therapeutic felon of surface analysis oral administration and externally.Furazolidone
Sheet is in western liquid, medicine, yellow powder mixing starch compressed tablets, has antibacterial, effect of parasite killing, and the property of medicine relatively relaxes, and is applied to wound
Mouth can be dissolved in blood or the transudate of wound in time, wound is not had zest, is mainly used in the antibacterial caused by sensitive organism
Property dysentery, enteritis, cholera, it is also possible to for typhoid fever, paratyphoid fever, giardiasis, trichomoniasis etc..Alumen sour-puckery flavor cold in nature,
Having stronger astriction, the traditional Chinese medical science is thought, has removing toxic substances parasite killing, quick-fried wet antipruritic, antidiarrheal of stopping blooding, effect of heat clearing away expectorant.In
Effect of medicine sulfur: external counteracting toxic substances, parasite killing, removing dampness, antipruritic;Three effects below have certain effect, counteracting toxic substances for sulfur
To sore, carbuncle and painful swelling, how alone compound recipe is embrocates all effectively, but effect is the strongest.Effect of Chinese medicine Camphora: sensible refreshment, wards off dirty promoting the circulation of QI,
Reducing swelling and alleviating pain, killing parasites for relieving itching.Natural camphor ball is usually the organic compound having fragranced extracted from Lignum cinnamomi camphorae branch and leaf, can
As a kind of moth-proof and mould-proof product, toxicity is relatively small.Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.The Radix Rehmanniae is used for consumption of YIN caused by febrile disease, crimson tongue
Excessive thirst, sends out speckle dermexanthesis, spits blood, epistaxis, laryngopharynx swelling and pain.Flos Lonicerae can dispelling wind-heat, be also apt to removing summer-heat blood poison, for various hot
Disease, such as fever of the body, dermexanthesis, sends out the cards such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, and equal effect is notable.Effect of Fructus Forsythiae and effect: heat clearing away solution
Poison;Dispersing swelling and dissipating binds anemopyretic cold;Main anemopyretic cold;Epidemic febrile disease;Pyretic stranguria urine retention;Carbuncle;Toxic swelling;Scrofula;Goiter;Sore throat.Spina Gleditsiae
Being the Spina jujubae of a kind of plant Fructus Gleditsia, be a herb, be considered pungent by the traditional Chinese medical science, Wen De, main effect is to draw out pus by applying a plaster to the affected part to dispel the wind, detumescence
Evacuation of pus, is mainly used on the dermatosis of health.Radix Achyranthis Bidentatae energy nourishing and protecting liver, foster kidney the kidney invigorating, blood-supplementing blood-nourishing, invigorating vital QI, tune
Reason the intestines and stomach, memory reinforcing, YIN nourishing nourishing YIN, appetite-stimulating indigestion-relieving, elimination edema, raising metabolism, defying age.Radix Glycyrrhizae property is put down, and sweet in the mouth has
Detoxify, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer;In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grow and cough lung moistening, emergency solution
Poison, is in harmonious proportion hundred medicines;Radix Glycyrrhizae also has antiinflammatory, antiviral, protecting liver and detoxication and strengthens immune effect.
The medicine of the therapeutic felon of oral administration and externally provides the benefit that: the therapeutic felon of oral administration and externally
Medicine belongs to diseases caused by exogenous pathogenic factor heresy poison by analysis whitlow, rotten bone is hindered in erosion, pyretic toxicity pents up, and takes the medicine with Pesticidal and sterilizing
External;Draw out pus by applying a plaster to the affected part with heat clearing away, the medicine of dissipating blood stasis of subsiding a swelling takes orally and coordinates as medicine, and theory of medicine is correct, and therapeutic effect is obvious.
Detailed description of the invention
The medicine of the therapeutic felon of oral administration and externally is further illustrated below with embodiment.
The medicine of the therapeutic felon of oral administration and externally is suitable for the agent that a whitlow patient uses
Amount medication amount be to combine by following each drug quality: one, external used medicine: Furazolidone tablet 1, Alumen 1 gram, sulfur 1 gram,
Camphora 1 gram;Two, endo-medicine: 15 grams of the Radix Rehmanniae, Flos Lonicerae 12 grams, Fructus Forsythiae 12 grams, Spina Gleditsiae 12 grams, Radix Achyranthis Bidentatae 12 grams, 7 grams of Radix Glycyrrhizae.
Using method: by 1 crushed into powder of external used medicine furazolidone, by 1 gram of crushed into powder of Camphora, then by furazolidone
Powder, camphor powder, sofril, Alumen powder mix homogeneously become mixed powder, and mixed powder is applied to suppurative finger affected part;With
Time, by 15 grams of the Chinese medicine for oral administration Radix Rehmanniae, Flos Lonicerae 12 grams, Fructus Forsythiae 12 grams, Spina Gleditsiae 12 grams, Radix Achyranthis Bidentatae 12 grams, 7 grams of Radix Glycyrrhizae mixing with
More than 30 minutes water intaking decocting liquids of 1.5 liters of soak by water are taken.
The medicine of the therapeutic felon of oral administration and externally uses checking, effectively through 20 many cases whitlow patients
Rate 100%, cure rate 100%.The human body that medicine of the present invention is equally applicable to some bacillary infringements and traumatic injury causes other
Suppurative or the nonsuppurative inflammation at position, curative effect is the most notable.
Claims (1)
1. the medicine of the therapeutic felon of oral administration and externally, is characterized in that combining by following each Chinese medicine quality part ratio: one,
External used medicine: Furazolidone tablet 1 part, Alumen 1 part, sulfur 1 part, Camphora 1 part;Two, endo-medicine: 15 parts of the Radix Rehmanniae, Flos Lonicerae 12
Part, Fructus Forsythiae 12 parts, Spina Gleditsiae 12 parts, Radix Achyranthis Bidentatae 12 parts, 7 parts of Radix Glycyrrhizae.
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104623112A (en) * | 2013-11-08 | 2015-05-20 | 陈洪波 | Plaster for treating snake-head furuncle |
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2016
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Publication number | Priority date | Publication date | Assignee | Title |
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CN104623112A (en) * | 2013-11-08 | 2015-05-20 | 陈洪波 | Plaster for treating snake-head furuncle |
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