CN106236963A - A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof - Google Patents

A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof Download PDF

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CN106236963A
CN106236963A CN201610729395.8A CN201610729395A CN106236963A CN 106236963 A CN106236963 A CN 106236963A CN 201610729395 A CN201610729395 A CN 201610729395A CN 106236963 A CN106236963 A CN 106236963A
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温红卫
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The present invention discloses a kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, being made up of the crude drug that weight ratio is 1:5 15 and the ethanol that mass concentration is 75%, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 10 30 parts, Rhizoma Curculiginis 10 20 parts, Galla Chinensis 10 30 parts, Herba Cistanches 10 30 parts, Radix Morindae Officinalis 10 20 parts, Flos Caryophylli 10 20 parts, Herba Asari 10 30 parts and Fructus Cnidii 10 30 parts.The Traditional Chinese medicine tincture preparation yang-strengthening for the treatment of impotence and premature ejaculation, effect of essence strengthening and the kidney invigorating that the present invention provides are notable, it is possible to effectively treat impotence and premature ejaculation, night sweat due to weak body physique, the disease such as weakness of QI, sore waist and aching in the waist and the back of suffering from a deficiency of the kidney.

Description

A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof.
Background technology
Sexual impotence also known as erection disturbance (being called for short ED in the world), refer to sexual be intended to requirement time, penis anorthosis or Erect the hardest, although or have erection and have a certain degree of hardness, but the enough time of sexual intercourse can not be kept, thus obstruction property Hand over and maybe can not complete sexual intercourse.In most cases, sexual impotence is not serious disease, but to middle-young patients, pressure is the biggest, often Affecting conjugal relation and cultural life, patient is the most worried, seeks medical advice everywhere, is eager to cure, and the most anxious more flaccidity, more flaccidity are the most anxious, are formed Vicious cycle.Current high selectivity PDE5 inhibitor, sldenafil (viagra), he answer that non-(Xi Aili) and Vardenafil (Ai Lida) etc. take clinical effective rate before sexual life and reach 70-80%.The side effect of modal PDE5 inhibitor for headache, Flushing, dyspepsia and nasal obstruction, all played a role by nitric oxide-cycli phosphate bird acid anhydride (NO-cGMP) approach, and its contraindication is equal For taking the patient of long-acting or fugitive nitric acid lipid drug.Following patient's takes PDE5 inhibitor may be risky: activeness is preced with Cardiopathia, congenital heart disease companion's cardiac insufficiency, hypotension, heart substantially expand, use combination drug resisting hypertension, use and prolong The medicine of long PDE5 half-life.The benefit of western medicine is rapid-action, but side effect is obvious, and needs long-term clothes Medicine.
Summary of the invention
It is an object of the invention to provide a kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof, this Traditional Chinese medicine tincture preparation is strengthened Sun rise flaccidity, essence strengthening and the kidney invigorating effect notable, it is possible to effectively treat impotence and premature ejaculation, night sweat due to weak body physique, suffer from a deficiency of the kidney weakness of QI, sore waist and aching in the waist and the back etc. Disease.
The technical solution adopted in the present invention is: a kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, weight ratio be 1:5-15 Crude drug and the ethanol that mass concentration is 75% make, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 10-30 part, Rhizoma Curculiginis 10-20 part, Galla Chinensis 10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Fructus Cnidii 10-30 part.
The preparation method of the Traditional Chinese medicine tincture preparation of described treatment impotence and premature ejaculation, comprises the following steps:
Step one, the preparation of crude drug
According to parts by weight take raw material Herba Epimedii 10-30 part, Rhizoma Curculiginis 10-20 part, Galla Chinensis 10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Fructus Cnidii 10-30 part, mix homogeneously, obtain mixing raw material, Standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 20-30min that temperature is 100-110 DEG C, cooling To 80-90 DEG C, and being incubated 1-3h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, continues Mixing raw material in abrupt release steam kettle after 5min, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, Keep 10-20min, take out, i.e. obtain crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and the mass concentration adding crude drug weight 5-15 times is 75% Ethanol, seal soak more than 72h, filter, the filtrate obtained be treatment impotence and premature ejaculation Traditional Chinese medicine tincture preparation.
Compared with prior art, the present invention at least has and has the advantage that and beneficial effect:
In the present invention, Herba Epimedii, warming and recuperating the kidney-YANG, yang-strengthening, for monarch drug;Radix Morindae Officinalis, Fructus Cnidii, Herba Cistanches, Rhizoma Curculiginis, strong muscle Bone, cures mainly Ying Yang road and does not lifts, for ministerial drug;Galla Chinensis, arresting seminal emission, essence is closed not solid, for adjuvant drug;Flos Caryophylli, Herba Asari, Xin Wen, have Warming the kidney to activate YANG plays the merit of flaccidity, for making medicine.The formula of the present invention through scientific compatibility, synergism between various raw materials, make tonifying YANG Rise flaccidity, essence strengthening and the kidney invigorating effect notable, it is possible to effectively treat impotence and premature ejaculation, night sweat due to weak body physique, the disease such as weakness of QI, sore waist and aching in the waist and the back of suffering from a deficiency of the kidney.
The preparation method of the present invention is simple, effective, and mixing raw material is by abrupt release, on the one hand energy after high temperature high pressure process Enough making the active ingredient in raw material be easier to discharge, the Chinese medicine ingredients content making the present invention is higher;On the other hand medicine exists Mutually merging during release, make synergism more deep, drug effect is more significantly.
Detailed description of the invention
A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, is 75% by the crude drug that weight ratio is 1:5-15 and mass concentration Ethanol is made, and described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 10-30 part, Rhizoma Curculiginis 10-20 part, five times Sub-10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Fructus Cnidii 10-30 Part.
The preparation method of the Traditional Chinese medicine tincture preparation of described treatment impotence and premature ejaculation, comprises the following steps:
Step one, the preparation of crude drug
According to parts by weight take raw material Herba Epimedii 10-30 part, Rhizoma Curculiginis 10-20 part, Galla Chinensis 10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Fructus Cnidii 10-30 part, mix homogeneously, obtain mixing raw material, Standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 20-30min that temperature is 100-110 DEG C, cooling To 80-90 DEG C, and being incubated 1-3h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, continues Mixing raw material in abrupt release steam kettle after 5min, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, Keep 10-20min, take out, i.e. obtain crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and the mass concentration adding crude drug weight 5-15 times is 75% Ethanol, seal soak more than 72h, in immersion process every 6h stir once, after having soaked filtration, the filtrate obtained is to be controlled Treat the Traditional Chinese medicine tincture preparation of impotence and premature ejaculation.
For making present disclosure become apparent, below in conjunction with specific embodiment, describe the present invention.
Embodiment 1:
A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, by the crude drug that weight ratio is 1:5 and ethanol system that mass concentration is 75% Becoming, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 10 parts, Rhizoma Curculiginis 10 parts, Galla Chinensis 10 parts, Herba Cistanches 10 parts, Radix Morindae Officinalis 10 parts, Flos Caryophylli 10 parts, Herba Asari 10 parts and Fructus Cnidii 10 parts.
The preparation method of the Traditional Chinese medicine tincture preparation of described treatment impotence and premature ejaculation, comprises the following steps:
Step one, the preparation of crude drug
Raw material Herba Epimedii, Rhizoma Curculiginis, Galla Chinensis, Herba Cistanches, Radix Morindae Officinalis, Flos Caryophylli, Herba Asari and cnidium monnieri is taken according to above-mentioned parts by weight Son, mix homogeneously, obtain mixing raw material, standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 20min that temperature is 100-110 DEG C, be cooled to 80-90 DEG C, and it is incubated 1h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, after continuing 5min Mixing raw material in abrupt release steam kettle, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, keep 10min, takes out, i.e. obtains crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and adds the second that mass concentration is 75% of crude drug weight 5 times Alcohol, seals and soaks more than 72h, filters, and the filtrate obtained is the Traditional Chinese medicine tincture preparation for the treatment of impotence and premature ejaculation.
Embodiment 2:
A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, by the crude drug that weight ratio is 1:15 and ethanol system that mass concentration is 75% Becoming, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 30 parts, Rhizoma Curculiginis 20 parts, Galla Chinensis 30 parts, Herba Cistanches 30 parts, Radix Morindae Officinalis 20 parts, Flos Caryophylli 20 parts, Herba Asari 30 parts and Fructus Cnidii 30 parts.
The preparation method of the Traditional Chinese medicine tincture preparation of described treatment impotence and premature ejaculation, comprises the following steps:
Step one, the preparation of crude drug
Raw material Herba Epimedii, Rhizoma Curculiginis, Galla Chinensis, Herba Cistanches, Radix Morindae Officinalis, Flos Caryophylli, Herba Asari and cnidium monnieri is taken according to above-mentioned parts by weight Son, mix homogeneously, obtain mixing raw material, standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 30min that temperature is 100-110 DEG C, be cooled to 80-90 DEG C, and it is incubated 3h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, after continuing 5min Mixing raw material in abrupt release steam kettle, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, keep 20min, takes out, i.e. obtains crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and the mass concentration adding crude drug weight 15 times is 75% Ethanol, seals and soaks more than 72h, filters, and the filtrate obtained is the Traditional Chinese medicine tincture preparation for the treatment of impotence and premature ejaculation.
Embodiment 3:
A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, by the crude drug that weight ratio is 1:10 and ethanol system that mass concentration is 75% Becoming, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 20 parts, Rhizoma Curculiginis 15 parts, Galla Chinensis 20 parts, Herba Cistanches 20 parts, Radix Morindae Officinalis 15 parts, Flos Caryophylli 15 parts, Herba Asari 20 parts and Fructus Cnidii 20 parts.
The preparation method of the Traditional Chinese medicine tincture preparation of described treatment impotence and premature ejaculation, comprises the following steps:
Step one, the preparation of crude drug
Raw material Herba Epimedii, Rhizoma Curculiginis, Galla Chinensis, Herba Cistanches, Radix Morindae Officinalis, Flos Caryophylli, Herba Asari and cnidium monnieri is taken according to above-mentioned parts by weight Son, mix homogeneously, obtain mixing raw material, standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 25min that temperature is 100-110 DEG C, be cooled to 80-90 DEG C, and it is incubated 2h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, after continuing 5min Mixing raw material in abrupt release steam kettle, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, keep 15min, takes out, i.e. obtains crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and the mass concentration adding crude drug weight 10 times is 75% Ethanol, seals and soaks more than 72h, filters, and the filtrate obtained is the Traditional Chinese medicine tincture preparation for the treatment of impotence and premature ejaculation.
Test data
The present invention is since developing, and heal the sick over thousands of example, and cure rate reaches more than 90%, and patient with severe symptoms uses about 2 months Recovery from illness.
Criterion of therapeutical effect:
Effective: impotence and premature ejaculation, night sweat due to weak body physique, the disease such as weakness of QI, sore waist and aching in the waist and the back of suffering from a deficiency of the kidney are wholly absent;
Effective: impotence and premature ejaculation, night sweat due to weak body physique, suffer from a deficiency of the kidney the disease such as weakness of QI, sore waist and aching in the waist and the back be improved significantly;
Invalid: impotence and premature ejaculation, night sweat due to weak body physique, the disease such as weakness of QI, sore waist and aching in the waist and the back of suffering from a deficiency of the kidney substantially are alleviated.
Result shows: use in the patient of Traditional Chinese medicine tincture preparation of the present invention, has the patient of 95% effective and effective, and symptom obtains Cure and be obviously improved.As can be seen here, yang-strengthening of the present invention, essence strengthening and the kidney invigorating effect notable, it is possible to effectively treatment sexual impotence is early Let out, night sweat due to weak body physique, the disease such as weakness of QI, sore waist and aching in the waist and the back of suffering from a deficiency of the kidney.
Model case:
Case 1: Zhang, man, 31 years old, suffers from sexual impotence half a year, uses Western medicine side effect big, and cure the symptoms, not the disease, use this later Bright 20 days, recovery from illness.
Case 2: Chen, man, 39 years old, suffer from sexual impotence 3 months, use the present invention 20 days, recovery from illness.
Case 3: Wu, man, 58 years old, suffers from sexual impotence 2 years, takes Western medicine side effect greatly, and cure the symptoms, not the disease, use this later Invent 2 months, recovery from illness.
Case 4: Lee, man, 35 years old, suffers from sexual impotence 1 year, takes Western medicine side effect greatly, and cure the symptoms, not the disease, use this later Invent 40 days, recovery from illness.
Case 5: time, man, 44 years old, suffers from sexual impotence 2 years, takes Western medicine side effect greatly, and cure the symptoms, not the disease, use this later Invent 3 months, recovery from illness.

Claims (2)

1. the Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, it is characterised in that crude drug and quality by weight ratio is 1:5-15 are dense Degree be 75% ethanol make, described crude drug is made up of following raw material according to parts by weight: Herba Epimedii 10-30 part, Rhizoma Curculiginis 10- 20 parts, Galla Chinensis 10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Serpentis Machine tool 10-30 part.
A kind of preparation method of the Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation, it is characterised in that include with Lower step:
Step one, the preparation of crude drug
According to parts by weight take raw material Herba Epimedii 10-30 part, Rhizoma Curculiginis 10-20 part, Galla Chinensis 10-30 part, Herba Cistanches 10-30 part, Radix Morindae Officinalis 10-20 part, Flos Caryophylli 10-20 part, Herba Asari 10-30 part and Fructus Cnidii 10-30 part, mix homogeneously, obtain mixing raw material, Standby;
First above-mentioned mixing raw material is put into steam kettle, after being passed through the steam insulation 20-30min that temperature is 100-110 DEG C, cooling To 80-90 DEG C, and being incubated 1-3h, insulation is warming up to 120 DEG C after terminating, and is passed through nitrogen and makes air pressure inside reach 2MPa, continues Mixing raw material in abrupt release steam kettle after 5min, then mixing raw material is transferred in the calorstat that temperature is not higher than 25 DEG C, Keep 10-20min, take out, i.e. obtain crude drug, standby;
Step 2, the preparation of Traditional Chinese medicine tincture preparation
Crude drug step one obtained is placed in sealing container, and the mass concentration adding crude drug weight 5-15 times is 75% Ethanol, seal soak more than 72h, filter, the filtrate obtained be treatment impotence and premature ejaculation Traditional Chinese medicine tincture preparation.
CN201610729395.8A 2016-08-26 2016-08-26 A kind of Traditional Chinese medicine tincture preparation treating impotence and premature ejaculation and preparation method thereof Pending CN106236963A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660218A (en) * 2004-12-13 2005-08-31 陈仁德 Chinese materia medica preparation for treating andropathy
CN103142700A (en) * 2013-03-27 2013-06-12 谢银芳 Externally applied liniment for treating premature ejaculation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1660218A (en) * 2004-12-13 2005-08-31 陈仁德 Chinese materia medica preparation for treating andropathy
CN103142700A (en) * 2013-03-27 2013-06-12 谢银芳 Externally applied liniment for treating premature ejaculation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
丁建等: "中药外用治疗勃起功能障碍概述", 《山东中医杂志》 *
董德河等: ""持久"系列药物治疗早泄60例", 《河南中医》 *

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