CN106236902A - A kind of medicine for treating urinary system calculus - Google Patents
A kind of medicine for treating urinary system calculus Download PDFInfo
- Publication number
- CN106236902A CN106236902A CN201610700097.6A CN201610700097A CN106236902A CN 106236902 A CN106236902 A CN 106236902A CN 201610700097 A CN201610700097 A CN 201610700097A CN 106236902 A CN106236902 A CN 106236902A
- Authority
- CN
- China
- Prior art keywords
- parts
- calculus
- semen
- medicine
- diuresis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 21
- 230000002485 urinary effect Effects 0.000 title claims abstract description 20
- 210000000582 semen Anatomy 0.000 claims abstract description 22
- 241000737263 Lygodium Species 0.000 claims abstract description 11
- 241001116755 Selliguea Species 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000002775 capsule Substances 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 3
- 241000282326 Felis catus Species 0.000 claims 1
- 208000004880 Polyuria Diseases 0.000 abstract description 15
- 230000035619 diuresis Effects 0.000 abstract description 15
- 230000001737 promoting effect Effects 0.000 abstract description 15
- 239000008280 blood Substances 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 11
- 229940079593 drug Drugs 0.000 abstract description 6
- 230000001105 regulatory effect Effects 0.000 abstract description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 4
- 208000026435 phlegm Diseases 0.000 abstract description 4
- 239000003440 toxic substance Substances 0.000 abstract description 4
- 210000004072 lung Anatomy 0.000 abstract description 3
- 230000001717 pathogenic effect Effects 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000004087 circulation Effects 0.000 abstract description 2
- 238000001816 cooling Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 230000023597 hemostasis Effects 0.000 abstract description 2
- 230000001939 inductive effect Effects 0.000 abstract description 2
- 231100000614 poison Toxicity 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 208000011580 syndromic disease Diseases 0.000 abstract description 2
- 231100000167 toxic agent Toxicity 0.000 abstract description 2
- 210000003734 kidney Anatomy 0.000 description 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 201000010099 disease Diseases 0.000 description 13
- 210000002700 urine Anatomy 0.000 description 13
- 210000003932 urinary bladder Anatomy 0.000 description 11
- 208000009911 Urinary Calculi Diseases 0.000 description 9
- 230000007812 deficiency Effects 0.000 description 7
- 208000006750 hematuria Diseases 0.000 description 6
- 208000037920 primary disease Diseases 0.000 description 6
- 239000004575 stone Substances 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 230000000994 depressogenic effect Effects 0.000 description 4
- 206010013990 dysuria Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 210000001635 urinary tract Anatomy 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 208000031868 Calculus ureteric Diseases 0.000 description 3
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 description 3
- 208000000014 Ureteral Calculi Diseases 0.000 description 3
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 239000011575 calcium Substances 0.000 description 3
- 229960003067 cystine Drugs 0.000 description 3
- 230000008451 emotion Effects 0.000 description 3
- 206010025482 malaise Diseases 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
- 210000003708 urethra Anatomy 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 229960003459 allopurinol Drugs 0.000 description 2
- OFCNXPDARWKPPY-UHFFFAOYSA-N allopurinol Chemical compound OC1=NC=NC2=C1C=NN2 OFCNXPDARWKPPY-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000002309 gasification Methods 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000001113 umbilicus Anatomy 0.000 description 2
- 210000000626 ureter Anatomy 0.000 description 2
- 208000008281 urolithiasis Diseases 0.000 description 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 description 1
- 206010007027 Calculus urinary Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012469 Cleome gynandra Nutrition 0.000 description 1
- 206010009866 Cold sweat Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 235000019082 Osmanthus Nutrition 0.000 description 1
- 241000333181 Osmanthus Species 0.000 description 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 208000008718 Pyuria Diseases 0.000 description 1
- 206010038419 Renal colic Diseases 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 240000007918 Tacca chantrieri Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- MXZRMHIULZDAKC-UHFFFAOYSA-L ammonium magnesium phosphate Chemical compound [NH4+].[Mg+2].[O-]P([O-])([O-])=O MXZRMHIULZDAKC-UHFFFAOYSA-L 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- QXDMQSPYEZFLGF-UHFFFAOYSA-L calcium oxalate Chemical compound [Ca+2].[O-]C(=O)C([O-])=O QXDMQSPYEZFLGF-UHFFFAOYSA-L 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000002574 cystoscopy Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000001524 infective effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 229940029329 intrinsic factor Drugs 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 150000003891 oxalate salts Chemical class 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000009527 percussion Methods 0.000 description 1
- 210000002640 perineum Anatomy 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 229950000688 phenothiazine Drugs 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 210000004706 scrotum Anatomy 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 229910052567 struvite Inorganic materials 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 150000007971 urates Chemical group 0.000 description 1
- 230000003202 urodynamic effect Effects 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of medicine for treating urinary system calculus, it is to be prepared from by the raw medicinal material of following weight proportion: Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, Herba clerodendranthi spicati 30 parts, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts.The present invention uses: Lygodium conforme C. Chr clearing away heat and promoting diuresis；Phymatopsis griffithiana (Hook.) J. Sm. relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, cooling blood for hemostasis；Semen Abutili relieving stranguria by diuresis；Radix Glycyrrhizae uralensis eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome；Radix Cudraniae dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling；Semen Mangiferae indicae reduces phlegm circulation of qi promoting；Herba clerodendranthi spicati clearing away heat-damp and promoting diuresis, Tonglin Paishi；Herba artemisiae lactiflorae promoting blood circulation to remove blood stasis, regulating QI to expel dampness；Triangle bubble clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.All medicines share, and play regulating qi to disperse stagnation, hard masses softening and resolving, clearing away heat-damp and promoting diuresis, effect that calculus is treating stranguria altogether.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine for treating urinary system calculus.
Background technology
Urinary calculi is the commonly encountered diseases of urinary system.Calculus is found in any position of kidney, bladder, ureter and urethra.But
It is common with kidney and ureteral calculus.Clinical manifestation has different because position, calculus place is different.Kidney and the typical case of ureteral calculus
Showing as renal colic and hematuria, before calculus causes angor outbreak, patient does not has any sensation, due to certain inducement, such as play
Strong motion, work, long-distance by bus etc., the angor that side waist is violent occurs suddenly, and radiates to lower abdomen and perineal position, with abdomen
Hematurias swollen, that Nausea and vomiting, degree are different；It is dysuria and urodynamic that vesical calculus mainly shows.Primary disease is China south
Area, side frequently-occurring disease, with Guangdong, osmanthus, Yunnan, Guizhou Province, river, Hunan, Jiangxi etc. save sickness rate as height, especially with the Delta of the Pearl River as district occurred frequently.The world
On, Britain, Holland, Thailand, Ye Doushi urolithiasis hotspot of India.Primary disease can occur at any age, but with between twenty and fifty man
Property is many, and sickness rate had and increased trend, especially with upper urinary stone showed increased nearly recent decades.Within 1976, once someone added up urinary calculi
Patient 2424 example, upper urinary stone accounts for 34%.Modern Western medicine, in addition to operative treatment, there is no specific short.
Primary disease is early recognized by the traditional Chinese medical science, the name of disease of existing " pouring " in Huangdi's Internal Classics, " Medical Treasures of the Golden Chamber " to the symptom of pouring,
Pathogenesis the most tentatively describes.Since the Tang Dynasty, having occurred specially controlling the square medicine of stranguria caused by urinary stone, so far, these theoretical and square medicines are to current urine
The determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of stone disease still has reference.
The cause of disease
Unclear urinary stone agnogenio, machine-processed is referred to as constitutional urinary calculi.
Metabolic urinary calculi, this kind of calculus is the most common, is to cause, such as thyroid merit due to internal or kidney intracellular metabolite disorder
Can hyperfunction, idiopathic urine calcium disease causes urine calcium to increase, the urate excretion of gout increases, renal tubule acidosis time phosphate increase in a large number
Add.The calculus that base is formed mostly is urate, carbonate, cystine xanthic calculus.
Secondary cases or Infective calculus.The predominantly antibacterial of urinary system infects, particularly can ureaclastic antibacterial and
Bacillus proteus can break down urea into free ammonia makes urine alkalize, and promotes phosphate, carbonate with cenobium or pus block as core
Form calculus.In addition the formation of calculus and race (Black people fall ill few), heredity (cystine stone inherited tendency), sex, the age,
Reason environment, dietary habit, nutriture and the illness of urinary tract narrow, the prostatic hyperplasia of such as urinary tract own etc. all have relation.
Clinical manifestation
For morbidity suddenly, violent lumbago, pain is many in persistence or intermittence, and along ureter in the clinical manifestation of urinary system calculus
Radiate to iliac fossa, perineum and scrotum etc.；Hematuria or pyuria, dysuria or uroflow interruption etc. occur.Calcium oxalate stone matter is hard,
Coarse, irregularly, often in Fructus Mori sample, sepia.Calcium phosphate, magnesium ammonium phosphate calculus are frangible, rough surface, irregularly, canescence,
Yellow or brown, visible delamination phenomenon in X-ray, it is commonly formed staghorn stone.Urate calculus matter is hard, smooth or irregular,
Being often multiple, yellow or rufous, pure urate calculus is not displayed in X-ray.Cystine stone is smooth, yellowish to yellowish-brown,
Waxy outward appearance.
Drug therapy
1. can be according to internal metabolism abnormal conditions, more oral medicines, such as phenothiazine drug, allopurinol, orthophosphate
Deng.
2. treatment by Chinese herbs is started with marrow, whole body therapeutic, makes disease start to take a turn for the better, and human body recovers normal physiological function.
Medical material involved in the present invention all seen from be recorded in " China book on Chinese herbal medicine ".
Summary of the invention
It is desirable to provide a kind of medicine for treating urinary system calculus, by selecting suitable medical material and joining
Ratio, reaches safely and effectively to cure the purpose of urinary system calculus.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine for treating urinary system calculus, it is characterised in that it is to be prepared by the raw medicinal material of following weight proportion
Form: Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, cat's whisker
Grass 30 parts, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts.
Illustrate the method have the benefit that below in conjunction with theories of Chinese materia medica
It has been recognised by the inventors that calculus is almost the epitome of concentrated urine.In the traditional Chinese medical science, its cause of disease has exopathogen people to invade, internal injury caused by excess of seven emotions,
The factors such as innate deficiency, its pathology mainly has the factor of damp-heat in lower-JIAO, deficiency of kidney-QI blood stasis three timid, depressed aspect.Damp-heat in lower-JIAO:
Damp and hot heresy, both can be by caused by the damp and hot invasion part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels in the external world, it is possible to caused by seven emotions pent-up fire-transformation, or because bladder water mansion is amassed wet
Accumulation of heat and cause to pent up and do not change.Penting up of damp-heat in lower-JIAO, not only hinders the gasification of kidney, and make kidney opens entire mistake department, and can make urine
Liquid tempers concentration, thus forms sandstone.Though so damp-heat in lower-JIAO can be interior raw, but for primary disease, being still pathogenic extrinsic factor.
Deficiency of kidney-QI is timid: the kidney being a water ZANG-organ, and opening of main water is entire, and bladder is the viscus likened to a pond, stores urine, holds the gasification of kidney and discharges.Suffer from a deficiency of the kidney then
Functioning of bladder is unfavorable, raw in deficiency and coldness, cold then solidify, and aqueous belongs to cold, and cold coagulation stagnation, water is wet cohesion, and because of deficiency of kidney-QI, loses in urine
Turbid can not drain therewith, Han Shui is harmonious with impurity in urine, and causes to be formed calculus, therefore suffering from a deficiency of the kidney is the intrinsic factor that formed of primary disease.
Depressed blood stasis: depressed blood stasis is the main pathogenesis of primary disease, it both can be the origin cause of formation of calculus, it is also possible to be the disease after calculus
Reason change.All waist injury of kidney, addicted to the red medicine of clothes, or the drinking water containing elements such as volume oxalates, calcium, magnesium, and depressed emotion
Etc. factor, all may result in qi depression to blood stasis.Strongly fragrant long heat-transformation, heat is moved the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, is made urine be decocted by it, with the passing of time become sandstone.Calculus shape
After one-tenth, illegally occupying in kidney, bladder, urine key etc., cause urinary tract catharsis not smooth, functioning of bladder is unfavorable, increases the weight of the stagnation of QI, water further
Road is jammed and is difficult to walk.Calculus both can increase, and can induce again incarceration, the hyperamization stasis of blood by the stagnation of QI, and sick position master then might be used in kidney and bladder, late period
Affect heart spleen, the most then involve whole body.Therefore regulating qi to disperse stagnation, hard masses softening and resolving, clearing away heat-damp and promoting diuresis are then taked in treatment, calculus is treating stranguria.
The present invention uses: Lygodium conforme C. Chr clearing away heat and promoting diuresis；Phymatopsis griffithiana (Hook.) J. Sm. relieving stranguria by diuresis, removing heat from the lung and dissipating phlegm, cooling blood for hemostasis；Semen Abutili
Relieving stranguria by diuresis；Radix Glycyrrhizae uralensis eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome；Radix Cudraniae dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling；Semen Mangiferae indicae reduces phlegm
Circulation of qi promoting；Herba clerodendranthi spicati clearing away heat-damp and promoting diuresis, Tonglin Paishi；Herba artemisiae lactiflorae promoting blood circulation to remove blood stasis, regulating QI to expel dampness；Triangle bubble clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.
All medicines share, and play regulating qi to disperse stagnation, hard masses softening and resolving, clearing away heat-damp and promoting diuresis, effect that calculus is treating stranguria altogether.
Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:
1, physical data
Inventor collects 90 example Patients with Urinary Stones between in February ,-2015 in April, 2012 altogether.It is randomly divided into: treatment group 45 example,
Matched group 45 example.Male 34 examples of wherein treatment group, female 11 example, age 27～58 years old, the course of disease 1～8 years；Matched group man 37 examples, female 8
Example, between age 26～60 years old, the course of disease 1～9 years.The data such as two groups of sexes, age, courses of disease there was no significant difference, and has comparability.
Diagnostic criteria
1. kidney, ureteral calculus
Waist or epigastrium continue dull pain or the violent angor of paroxysmal, are radiated to homonymy hypogastric region or pudendum, can during angor outbreak
With being in a cold sweat, vomit, feeling sick, bilateral has the person of blocking can have urine retention simultaneously；
Can there be naked eyes or microscopic hematuria, hematuria aggravation during angor outbreak；
Calculus shade seen from x-ray urinary system plain film great majority；
IVU can further determine that in plain abdominal radiograph, calcification shadow is the most relevant with urinary system, it may be determined that calculus place
Position, with or without blocking, and can show x-ray radioparent calculus；
ING, B ultrasonic, CT have certain help to diagnosis.
2. vesical calculus
Dysuria, uroflow are interrupted, are urinated end severe pain and hematuria.Occurring frequent micturition, urgent micturition during concurrent infection, pain increases the weight of；
Bladder area X-ray examination or take the photograph calculus shadow seen from sheet；
Metal urethral bougie enters bladder, has and calculus percussion or abrasive feel；
Calculus seen from cystoscopy；
B ultrasonic has certain help to diagnosis.
3. calculus of urethra
Dysuria, the uroflow sound of rain pattering or urine retention；
Along the accessible calculus of urethra or Rectal tonch, or touch calculus with metal bougie；
Calculus shade seen from x-ray plain film.
1. inclusive criteria meets diagnostic criteria；2. the age 18～70 years old；3. compliance is good；Sign informed consent the most voluntarily
Book.
Exclusion standard 1. gestation, women breast-feeding their children；2. suffer from severe cardiac, lung, liver, renal disease patient；3. spiritedness system
System disease, it is impossible to partner treatment person；4. through the patient of other drug treatment after morbidity.
2, Therapeutic Method
Treatment group is administered orally the capsule that the present invention prepares according to specific embodiment 3, three times a day.Treat 2 months.
Matched group is administered orally allopurinol tablet, each 50mg, three times a day.Treat 2 months.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
1. recovery from illness: after treatment, calculus is discharged, transference cure, and x-ray check urinary tract original radiopaque calculus shade disappears, or treatment
Though having no in that calculus is discharged, but clinical symptoms, sign disappear, x line check work time is above does not all find calculus shade；
The most effective: after treatment, there is calculus to discharge, but do not drain, or calculus shade checked by x line, and oneself does not substantially move down person；
The most invalid: after treatment, have no that calculus is discharged, x line etc. is checked, and calculus position is without substantially changing, or moves down less than 3 centimetres..
3.2 treatment statistical results are shown in Table 1.
1 liang of table group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) | Obvious adverse reaction example |
| Treatment group | 45 | 23 | 19 | 3 | 93% | 0 |
| Matched group | 45 | 3 | 12 | 30 | 33% | 0 |
Visible, urinary system calculus can safely and effectively be treated by the medicine that the present invention prepares, and cure rate is high.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: Lygodium conforme C. Chr 22 grams, Phymatopsis griffithiana (Hook.) J. Sm. 12 grams, Semen Abutili 10 grams, Radix Glycyrrhizae uralensis 3 grams, Radix Cudraniae 19 grams, Semen Mangiferae indicae 9 grams,
Herba clerodendranthi spicati 30 grams, Herba artemisiae lactiflorae 12 grams, triangle steep 12 grams；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts
Boil 1 hour, filter；Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of adult normal.
For treating urinary system calculus.Oral, the most once.
Embodiment 2
Weigh: Lygodium conforme C. Chr 22 grams, Phymatopsis griffithiana (Hook.) J. Sm. 12 grams, Semen Abutili 10 grams, Radix Glycyrrhizae uralensis 3 grams, Radix Cudraniae 19 grams, Semen Mangiferae indicae 9 grams,
Herba clerodendranthi spicati 30 grams, Herba artemisiae lactiflorae 12 grams, triangle steep 12 grams；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts
1.5 hours, filter；Merging filtrate, concentrates, and is dried, and packaging must meet the powder of one day consumption of adult normal.
For treating urinary system calculus.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Weigh: Lygodium conforme C. Chr 22 grams, Phymatopsis griffithiana (Hook.) J. Sm. 12 grams, Semen Abutili 10 grams, Radix Glycyrrhizae uralensis 3 grams, Radix Cudraniae 19 grams, Semen Mangiferae indicae 9 grams,
Herba clerodendranthi spicati 30 grams, Herba artemisiae lactiflorae 12 grams, triangle steep 12 grams；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor,
Concentrate, be dried, load capsule shells, the capsule of one day consumption of adult normal must be met.
For treating urinary system calculus.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. the medicine being used for treating urinary system calculus, it is characterised in that it is by the raw medicinal material system of following weight proportion
For forming: Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, cat
Moss 30 parts, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts.
2. the medicine for treating urinary system calculus as claimed in claim 1, it is characterised in that its preparation method is: weigh:
Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, Herba clerodendranthi spicati 30
Part, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour,
Filter；Merging filtrate, is concentrated into 120 parts, obtains decoct；Above-mentioned part each means weight portion.
3. the medicine for treating urinary system calculus as claimed in claim 1, it is characterised in that its preparation method is: weigh:
Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, Herba clerodendranthi spicati 30
Part, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts 1.5 hours,
Filter；Merging filtrate, concentrates, and is dried, and packaging obtains powder；Above-mentioned part each means weight portion.
4. the medicine for treating urinary system calculus as claimed in claim 1, it is characterised in that its preparation method is: weigh:
Lygodium conforme C. Chr 22 parts, Phymatopsis griffithiana (Hook.) J. Sm. 12 parts, Semen Abutili 10 parts, Radix Glycyrrhizae uralensis 3 parts, Radix Cudraniae 19 parts, Semen Mangiferae indicae 9 parts, Herba clerodendranthi spicati 30
Part, Herba artemisiae lactiflorae 12 parts, triangle steep 12 parts；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, dry
Dry, load capsule shells, obtain capsule；Above-mentioned part each means weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610700097.6A CN106236902A (en) | 2016-08-23 | 2016-08-23 | A kind of medicine for treating urinary system calculus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610700097.6A CN106236902A (en) | 2016-08-23 | 2016-08-23 | A kind of medicine for treating urinary system calculus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106236902A true CN106236902A (en) | 2016-12-21 |
Family
ID=57595749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610700097.6A Pending CN106236902A (en) | 2016-08-23 | 2016-08-23 | A kind of medicine for treating urinary system calculus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106236902A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117224637A (en) * | 2023-11-16 | 2023-12-15 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing sheep urinary stones |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920033A (en) * | 2014-04-10 | 2014-07-16 | 李恩东 | Traditional Chinese medicinal composition for treating calculi |
| CN104398998A (en) * | 2014-12-10 | 2015-03-11 | 李穆 | Traditional Chinese medicine composition for treating urinary calculi |
| CN104435341A (en) * | 2014-09-23 | 2015-03-25 | 陈伟 | Traditional Chinese medicine formula for treating calculus |
| CN105327180A (en) * | 2015-11-25 | 2016-02-17 | 董芳 | Traditional Chinese medicine preparation for treating kidney stones |
| CN105687375A (en) * | 2016-03-21 | 2016-06-22 | 刘琴兰 | Medicine for treating lithiasis in urinary system |
-
2016
- 2016-08-23 CN CN201610700097.6A patent/CN106236902A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920033A (en) * | 2014-04-10 | 2014-07-16 | 李恩东 | Traditional Chinese medicinal composition for treating calculi |
| CN104435341A (en) * | 2014-09-23 | 2015-03-25 | 陈伟 | Traditional Chinese medicine formula for treating calculus |
| CN104398998A (en) * | 2014-12-10 | 2015-03-11 | 李穆 | Traditional Chinese medicine composition for treating urinary calculi |
| CN105327180A (en) * | 2015-11-25 | 2016-02-17 | 董芳 | Traditional Chinese medicine preparation for treating kidney stones |
| CN105687375A (en) * | 2016-03-21 | 2016-06-22 | 刘琴兰 | Medicine for treating lithiasis in urinary system |
Non-Patent Citations (1)
| Title |
|---|
| 熊有明: "排石汤治疗泌尿系结石34例", 《河南中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117224637A (en) * | 2023-11-16 | 2023-12-15 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing sheep urinary stones |
| CN117224637B (en) * | 2023-11-16 | 2024-02-02 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing sheep urinary stones |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101884770B (en) | Chinese medicinal preparation for treating urolithiasis and preparation method thereof | |
| CN1325083C (en) | Medicinal composition for removing dampness to relieve itching and its preparation method and uses | |
| CN100531769C (en) | Chinese medicine composition for treating gout and preparing method thereof | |
| CN102423423B (en) | Traditional Chinese medicine for treating urinary tract infection | |
| CN100417402C (en) | Liposoluble traditional medicine bougie for treating acute and chronic prostatitis, and manufacturing technique thereof | |
| CN102266472B (en) | Chinese medicinal composition for preventing and/or treating diabetic nephropathy and preparation method thereof | |
| CN102210753B (en) | Traditional Chinese medicine composition for treating lithiasis in urinary system | |
| CN106236902A (en) | A kind of medicine for treating urinary system calculus | |
| CN109820943A (en) | A kind of strong medicine preparation and preparation method thereof for treating gout | |
| CN104784549A (en) | Traditional Chinese medicine for treating allergic rhinitis | |
| CN108619302A (en) | A kind of Chinese medicinal decoction for treating senile ulcer colitis | |
| CN100460001C (en) | Chinese medicinal composition for treating chronic prostate and its preparation | |
| CN102949613A (en) | Health-care product particle for treating urinary calculus and preparation method thereof | |
| CN103191399A (en) | Traditional Chinese medicine composition for treating bronchial asthma in acute-outbreak period | |
| CN102552767B (en) | Traditional Chinese medicine for treating kidney stone, preparation method and administration mode | |
| CN105687375A (en) | Medicine for treating lithiasis in urinary system | |
| CN100394976C (en) | Chinese medicine for withdrawal of drug dependence | |
| CN101129823B (en) | Orally taken traditional Chinese medicine composition for treating anaphylactoid purpura | |
| CN104800675A (en) | Medicament for treating active ulcerative colitis | |
| CN103920017B (en) | A kind of pharmaceutical composition treating cervicitis | |
| CN108524740A (en) | A kind of Chinese medicinal formulae for treating rheumatoid arthritis | |
| CN103432401A (en) | Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer | |
| CN103830646B (en) | A kind of preparation method of the pharmaceutical composition treating kidney or ureter stone | |
| CN1041603C (en) | Traditional Chinese medicine for treating prostatitis and urinary retention and production method thereof | |
| CN100512870C (en) | Medicine for treating psoriasis and method for preparing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161221 |
|
| WD01 | Invention patent application deemed withdrawn after publication |