CN106214920A - A kind of medicine treating syphilis and preparation method thereof - Google Patents

A kind of medicine treating syphilis and preparation method thereof Download PDF

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CN106214920A
CN106214920A CN201610702509.XA CN201610702509A CN106214920A CN 106214920 A CN106214920 A CN 106214920A CN 201610702509 A CN201610702509 A CN 201610702509A CN 106214920 A CN106214920 A CN 106214920A
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徐洪安
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a kind of medicine treating syphilis and preparation method thereof, it is mainly prepared from according to a certain weight ratio by Radix Angelicae Sinensis, Flos Lonicerae, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Zaocys, Periostracum Cicadae, Fructus Tribuli, Radix Trichosanthis, Cortex Dictamni, medicine of the present invention has heat-clearing and toxic substances removing, expelling wind and dampness, the function of benefiting essence-blood, for treating syphilis instant effect, good effect, do not recur.

Description

A kind of medicine treating syphilis and preparation method thereof
Technical field
The present invention relates to a kind of medicine treating syphilis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Syphilis is the sexually transmitted disease (STD) chronic, systemic caused by pale (syphilis) spirillum.The traditional Chinese medical science then think syphilis with Spleen lung is damp and hot, and phlegm-damp stream gathers, and pyretic toxicity pents up relevant.Owing to western medicine side effect is big, therefore people are to effectively treatment syphilis There is great demand in Chinese medicine, up to now, does not the most find the relevant report about the present invention.
Summary of the invention
The research of the present inventor's foundation theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found and effectively treat syphilis Medicine, thus complete the present invention.
It is an object of the invention to provide the Chinese medicine composition of a kind of effective treatment syphilis.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention be select Radix Angelicae Sinensis, Flos Lonicerae, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Zaocys, Periostracum Cicadae, Fructus Tribuli, Radix Trichosanthis, Cortex Dictamni, Semen Sesami Nigrum, Rhizoma Smilacis Glabrae medicine are combined preparation, and these drug regimens make each efficacy of drugs produce collaborative work With such that it is able to effectively treat syphilis.Wherein select Radix Angelicae Sinensis be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, enrich blood and Blood, menstruction regulating and pain relieving, to moisturize the function of laxation, control menoxenia, amenorrhea is suffered from abdominal pain, and abdominal mass knot is poly-, metrorrhagia, headache due to deficiency of blood, dizziness, flaccidity Numbness, dryness of the intestine difficulty just, weight after bloody dysentery, ulcer sores, incised wound, injury from falling down selects Flos Lonicerae, and to be because its nature and flavor sweet, cold, enter lung, Stomach warp, has heat clearing away, the function of removing toxic substances, controls epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Radix Glycyrrhizae is selected to be because Its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, and the function of coordinating the actions of various ingredients in a prescription is processed use, controlled weakness of the spleen and stomach, Lack of appetite, loose stool of suffering from abdominal pain, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened；Raw use, controls laryngopharynx swelling and pain, peptic ulcer, carbuncle skin ulcer Infections, solves poison of drug and alimentary toxicosis.The Radix Paeoniae Alba is selected to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, slow termination Bitterly, yin fluid astringing receives the function of antiperspirant, controls the chest and abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, band Under.Radix Saposhnikoviae is selected to be because its property acrid-sweet flavor, temperature, enter bladder, lung, spleen channel, deliver, dispel the wind, win wet, the function of pain relieving, control Affection of exogenous wind-cold, has a headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, and joint is ached, and extremity contraction is anxious, tetanus.Zaocys is selected to be because it Nature and flavor are sweet, flat, return Liver Channel, have dispelling, collateral-activating, spasmolytic, dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, tic spasm, skin pruritus, leprosy. Periostracum Cicadae is selected to be because its property sweet-salty, cool, enter lung, Liver Channel, have scattered wind heat, lung qi dispersing, determine the function of convulsion, control affection due to external wind and heat, cough Coughing hoarseness, measles without adequate eruption, rubella pruritus, children's shies, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Selection Fructus Tribuli is Because its nature and flavor toil, temperature, enter liver, lung meridian, have scattered wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood, control headache, itching over the body, conjunctival congestion swells nebula, Fullness in the chest, cough with dyspnea, abdominal mass, breast is difficult, carbuncle, scrofula.It is because its nature and flavor sweetness and bitterness acid with Radix Trichosanthis, cool, enter lung, stomach warp, have and promote the production of body fluid, Quench the thirst, pathogenic fire reducing, moisturize, evacuation of pus, the function of detumescence, control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula.Select white It is bitter that Cortex Dictamni is because its nature and flavor, salty, cold, enters spleen, stomach warp, dispels the wind, dampness, heat clearing away, and the function of removing toxic substances controls wind heat sore, scabies Tinea, itchy skin eruption, rheumatic arthralgia, jaundice.Selecting Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have Invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Choosing It is because its property slightly sweet flavor with Rhizoma Smilacis Glabrae, flat, enter liver, stomach warp, have removing toxic substances, dehumidifying, the function in profit joint, control syphilis, stranguria with turbid discharge, muscle Bone spasm and pain, tinea pedis, furuncle, carbuncle, scrofula.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, the consumption of each component under In stating weight range, all there is preferable curative effect
Radix Angelicae Sinensis 25-35 gram, Flos Lonicerae 25-35 gram, 25-35 gram of Radix Glycyrrhizae, Radix Paeoniae Alba 15-25 gram, Radix Saposhnikoviae 15-25 gram, Zaocys 15-20 Gram, Periostracum Cicadae 15-25 gram, Fructus Tribuli 10-15 gram, Radix Trichosanthis 10-20 gram, Cortex Dictamni 10-20 gram, Semen Sesami Nigrum 10-20 gram, Rhizoma Smilacis Glabrae 110-130 gram.
It is preferably
Radix Angelicae Sinensis 30 grams, Flos Lonicerae 30 grams, 30 grams of Radix Glycyrrhizae, the Radix Paeoniae Alba 20 grams, Radix Saposhnikoviae 20 grams, Zaocys 20 grams, Periostracum Cicadae 20 grams, Fructus Tribuli 12 grams, Radix Trichosanthis 15 grams, Cortex Dictamni 15 grams, Semen Sesami Nigrum 15 grams, Rhizoma Smilacis Glabrae 120 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, slightly dries in the air, and section is dried；
2, Flos Lonicerae: sieve removes silt, picks clean impurity；
3, Radix Glycyrrhizae: pick decontamination, cleans, be soaked in water to eighty per cant thoroughly time, pull out, run through, section, airing；
4, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, and solarization is dried in the air, and profit to inside and outside humidity is uniform, cuts Sheet, is dried；
5, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry；
6, Zaocys: take crude drug, brushes away ash bits, and the used time decaptitates, squama, cutting；
7, Periostracum Cicadae: pick decontamination, cleans and dries；
8, Fructus Tribuli: silt is removed in drift, the hard thorn of Ex-all residual；
9, Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening to inside and outside humidity is uniform, section, Dry, or wash, pull out, shine the most dry, be pounded fritter；
10, Cortex Dictamni: pick clean impurity, removes rough bark, cleans, slightly moistens, and section is dried；
11, Semen Sesami Nigrum: take crude drug, removes impurity, and sieve removes chip；
12, Rhizoma Smilacis Glabrae: floating with water logging, change water 1 time every day in summer, spring, every 2 days of autumn change water 1 time, and winter can change water 1 time on 3rd, anti- The most smelly, till soaking, pull section out, be dried in time.
Two, preparation
1, by the Radix Angelicae Sinensis cooked, Flos Lonicerae, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Zaocys, Periostracum Cicadae, Fructus Tribuli, Radix Trichosanthis, Cortex Dictamni, Semen Sesami Nigrum, Rhizoma Smilacis Glabrae put into decocting container, and add water 6 times amount for the first time, and after soaking 100 minutes, intense fire decocts boiling, then with civilian Fire decocts 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured in container；
2, the medicinal residues of filtration being added 4 times amount, intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor；
3, by twice decoction liquor mixing and stirring, it is divided into 2 doses to take.
In prescription, Flos Lonicerae has the function of heat-clearing and toxic substances removing to be monarch drug；Cortex Dictamni dispels the wind, dampness, heat clearing away, removing toxic substances；Rhizoma Smilacis Glabrae has Removing toxic substances, dehumidifying, the function in profit joint, the two is ministerial drug, and three taste medicines play heat-clearing and toxic substances removing jointly, dispel the wind, dampness, dehumidifying, Li Guan The effect of joint, treatment syphilis effect is comprehensive, and with heat-clearing and toxic substances removing, dispels the wind, and dehumidifying is that master can be effected a permanent cure, and Radix Saposhnikoviae is delivered, and dispels the wind, victory Wet, the function of pain relieving is adjuvant drug, and Semen Sesami Nigrum has an invigorating the liver and kidney, benefiting essence-blood, and the dry function of intestine moistening is for making medicine, and medicine all with remainder is to control Mark.
Medicine of the present invention has heat-clearing and toxic substances removing, expelling wind and dampness, the function of benefiting essence-blood, is used for treating syphilis, short treating period, takes effect Hurry up, non-relapse after healing.
The beneficial effect of of the present invention medicine is expanded on further below by way of test example, these test examples include this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Taking rabbit 30, male and female dual-purpose, body weight 2.0 2.5kg, divide two groups, often group 15, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is that administration by gavage is given Medicine, twice daily, serve on 7 days, observes every day and is administered reaction, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad Toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept syphilis out-patient totally 11 example for medical treatment.
2, diagnostic criteria
Classical symptom is that genital surface is slightly rotten to the corn or fester, a little secretions, in flesh pink or kermesinus, total lymphoid Knot enlargement, pudendum and crissum moist papule and flat condyloma etc..
3, Therapeutic Method
Selecting above-mentioned medicament, take to patient, each take 1 dose, every day is early, evening respectively takes 1 time, within 10 days, is a course for the treatment of, continuously Take 3 courses for the treatment of.
4, efficacy assessment standard
Effective: syphilis transference cure, body constitution recovers normal, recovery from illness；
Taking a turn for the better: the erosion of subjects reproductive's device surface, fester, have secretions, the phenomenon of lymphadenectasis alleviates, and syphilis symptom is obvious Taking a turn for the better, body constitution is progressively recovered；
Invalid: not reach improvement standard person.
5, therapeutic outcome (see table)
In above-mentioned treatment, by Drug therapy syphilitic 11 example of the present invention, effective 7 examples of result, obvious effective rate is 63.63%, takes a turn for the better 3 examples, improvement rate is 27.27%, invalid 1 example, and total effective rate is 90.9%.

Claims (3)

1. the medicine treating syphilis, it is characterised in that: it is made up of the crude drug in following weight range:
Radix Angelicae Sinensis 25-35 gram, Flos Lonicerae 25-35 gram, 25-35 gram of Radix Glycyrrhizae, Radix Paeoniae Alba 15-25 gram, Radix Saposhnikoviae 15-25 gram, Zaocys 15-20 Gram, Periostracum Cicadae 15-25 gram, Fructus Tribuli 10-15 gram, Radix Trichosanthis 10-20 gram, Cortex Dictamni 10-20 gram, Semen Sesami Nigrum 10-20 gram, Rhizoma Smilacis Glabrae 110-130 gram.
Medicine the most according to claim 1, the consumption of the most each crude drug is:
Radix Angelicae Sinensis 30 grams, Flos Lonicerae 30 grams, 30 grams of Radix Glycyrrhizae, the Radix Paeoniae Alba 20 grams, Radix Saposhnikoviae 20 grams, Zaocys 20 grams, Periostracum Cicadae 20 grams, Fructus Tribuli 12 grams, Radix Trichosanthis 15 grams, Cortex Dictamni 15 grams, Semen Sesami Nigrum 15 grams, Rhizoma Smilacis Glabrae 120 grams.
The preparation method of medicine the most according to claim 1 or claim 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Angelicae Sinensis: pick decontamination, cleans, moistening, slightly dries in the air, and section is dried；
(2) Flos Lonicerae: sieve removes silt, picks clean impurity；
(3) Radix Glycyrrhizae: pick decontamination, cleans, be soaked in water to eighty per cant thoroughly time, pull out, run through, section, airing；
(4) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, and solarization is dried in the air, and profit to inside and outside humidity is uniform, Section, is dried；
(5) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry；
(6) Zaocys: take crude drug, brushes away ash bits, and the used time decaptitates, squama, cutting；
(7) Periostracum Cicadae: pick decontamination, cleans and dries；
(8) Fructus Tribuli: silt is removed in drift, the hard thorn of Ex-all residual；
(9) Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening to inside and outside humidity is uniform, cuts Sheet, dries, or washes, and pulls out, shines the most dry, is pounded fritter；
(10) Cortex Dictamni: pick clean impurity, removes rough bark, cleans, slightly moistens, and section is dried；
(11) Semen Sesami Nigrum: take crude drug, removes impurity, and sieve removes chip；
(12) Rhizoma Smilacis Glabrae: floating with water logging, change water 1 time every day in summer, spring, every 2 days of autumn change water 1 time, and winter can change water 1 time on 3rd, anti- The most smelly, till soaking, pull section out, be dried in time；
(2) prepare
(1) by the Radix Angelicae Sinensis cooked, Flos Lonicerae, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Zaocys, Periostracum Cicadae, Fructus Tribuli, Radix Trichosanthis, Cortex Dictamni, Semen Sesami Nigrum, Rhizoma Smilacis Glabrae put into decocting container, and add water 6 times amount, and after soaking 100 minutes, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured in container；
(2) add water 4 times amount by the medicinal residues of filtration, and intense fire boils, then with slow fire boiling 20 minutes, filters to obtain second time decoction liquor；
(3) by twice decoction liquor mixing and stirring, it is divided into 2 doses to take.
CN201610702509.XA 2016-08-23 2016-08-23 A kind of medicine treating syphilis and preparation method thereof Withdrawn CN106214920A (en)

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Publication number Priority date Publication date Assignee Title
CN103182039A (en) * 2013-03-31 2013-07-03 张秀兰 Medicament for treating syphilis, and preparation method thereof
CN103816441A (en) * 2012-11-19 2014-05-28 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine for treating syphilis

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CN103816441A (en) * 2012-11-19 2014-05-28 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine for treating syphilis
CN103182039A (en) * 2013-03-31 2013-07-03 张秀兰 Medicament for treating syphilis, and preparation method thereof

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